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Hu Dou-Dou DD Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, P.R. China. - - 2014
Aim: Angiogenesis is considered an important pathophysiological feature of portal hypertension. We investigated the ability of angiogenesis, as CD34-positive microvessel density (MVD), to differentiate portal pressure in a CCl4-induced rat cirrhosis model. Methods: Cirrhosis was induced by intraperitoneal injection of carbon tetrachloride in 46 male adult Sprague-Dawley rats. A catheter ...
Saura Marta M Laboratory of Pathophysiology of the Vascular Wall, Physiology Unit, Department of Systems Biology, Laboratory of Renal Physiology and Experimental Nephrology, Cell Biology Unit, Department of Biomedicine and Biotechnology, and Department of Medicine and Medical Specialties, University of Alcalá, Alcalá de Henares, Spain; Laboratory of Pathophysiology of the Vascular Wall, Physiology Unit, Department of Systems Biology, Laboratory of Renal Physiology and Experimental Nephrology, Cell Biology Unit, Department of Biomedicine and Biotechnology, and Department of Medicine and Medical Specialties, University of Alcalá, Alcalá de Henares, - - 2014
Bisphenol A (BPA) is found in human urine and fat tissue. Higher urinary BPA concentrations are associated with arterial hypertension. To shed light on the underlying mechanism, we orally administered BPA (4 nM to 400 μM in drinking water) to 8-wk-old CD11 mice over 30 d. Mice developed dosage-dependent high ...
Olesen Jacob - - 2014
A noninvasive method for estimating 2-D pressure gradients from ultrasound vector velocity data is presented. It relies on vector velocity fields acquired using the transverse oscillation method during steady flow conditions. The pressure gradients are calculated from the velocity fields using the Navier-Stokes equations. Scans of a carotid bifurcation phantom ...
Spartano Nicole L NL Department of Exercise Science, Syracuse University, Syracuse, NY, USA. Electronic address: - - 2014
Brachial blood pressure (BP) reactivity to stress predicts large artery damage and future cardiovascular (CV) events. Central BP is an emerging risk factor associated with target organ damage (TOD). Currently, little is known about the central BP response to mental stress and its association to TOD. Twenty-five healthy, non-obese adults ...
Owolabi Mayowa O MO Department of Medicine, University of Ibadan, Ibadan, - - 2014
Stroke is the second-leading cause of death in low- and middle-income countries, but use of evidence-based therapies for stroke prevention in such countries, especially those in Africa, is extremely poor. This study is designed to enhance the implementation and sustainability of secondary stroke-preventive services following hospital discharge. The primary study ...
Alnima Teba T Maastricht University Medical Center, Department of Internal Medicine, P. Debyelaan 25, 6229 HX, Maastricht, The - - 2014
Uncontrolled or resistant hypertension is still a major problem facing many physicians daily in the clinic. Several new therapies are being developed to help those patients whose blood pressure does not respond sufficiently to regular antihypertensive medication. One of these promising therapies is electrical activation of the carotid sinus baroreflex. ...
- - 2014
High blood pressure is common in acute stroke and associated with a worse functional outcome. Many patients who present with acute stroke are taking prescribed antihypertensive therapy before their stroke. ENOS tested whether lowering blood pressure and continuing pre-stroke antihypertensive therapy are each safe and effective. This study is an ...
Parvinian Ahmad A University of Illinois Hospital and Health Sciences System, Department of Radiology. Chicago, IL, - - 2014
Purpose. To elucidate the impact of right atrial (RA) pressure on early mortality after transjugular intrahepatic portosystemic shunt (TIPS). Material and methods. In this single institution retrospective study, 125 patients (M:F = 75:50, mean age 55 years) who underwent TIPS with recorded intra-procedural RA pressures between 1999-2012 were studied. Demographic ...
Kent Marc M Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA - - 2014
Objective-To determine the prevalence of ischemic stroke in Greyhounds and determine whether affected dogs had coagulation abnormalities and hypertension. Design-Multi-institutional, retrospective study. Animals-21 dogs. Procedures-Medical records (including diagnostic testing results) and MRI images of the brain were reviewed for Greyhounds with ischemic stroke that had been evaluated at 4 institutions. ...
Sen Ayan A Henry Ford Hospital, Department of Emergency Medicine, Detroit, - - 2014
Non-invasive, continuous hemodynamic monitoring is entering the clinical arena. The primary objective of this study was to test the feasibility of such monitoring in a pilot sample of Emergency Department (ED) stroke patients. Secondary objectives included analysis of hemodynamic variability and correlation of continuous blood pressure measurements with standard measurements. ...
Feldstein Carlos A CA Department of Internal Medicine, Hypertension Program, Hospital de Clínicas José de San Martín, University of Buenos Aires, Buenos Aires, Argentina. Electronic address: - - 2014
Albeit hypertension is a leading risk factor for an initial stroke, the role of blood pressure (BP) lowering to prevent a subsequent stroke is controversial. The present systematic review searched randomized trials published from January 1990 to January 2014 with the aim to assess antihypertensive treatment effects on recurrent stroke ...
Zanchetti Alberto A aIstituto Auxologico Italiano bUniversità di Milano, Milan, Italy cFuWai Hospital and Cardiovascular Institute dBeijing Hypertension League Institute, Beijing, China eUniversità Milano-Bicocca fOspedale San Gerardo, Milan, Italy gOslo University Hospital, Oslo, Norway hUniversity of Valencia, Madrid, Spain iMedical University of Gdansk, Gdansk, Poland jUniversity of Glasgow, Glasgow, UK kLund University, Scania University Hospital, Malmö, Sweden lTallinn University of Technology, Tallinn, Estonia mEuropean Hospital Georges Pompidou, Paris, France nUniversità di Brescia, Spedali Civili, Brescia, Italy oBeijing Anzhen Hospital, Beijing pShanghai Hypertension Institute, China qComplutense University rHospital 12 de Octubre sHospital Clínico San Carlos, Madrid, Spain tCentro Hospitalar de Entre o Douro e Vouga, E.P.E., Portugal uNephrology and Hypertension, University Hospital, Erlangen, Germany vUniversity Hospital of Lausanne, Lausanne, Switzerland wMedical University of Lodz, Poland xCharles University Medical School I and Thomayer Hospital, Prague, Czech Republic ySt. Imre University Teaching Hospital, Budapest, Hungary zAlmazov Federal Heart, Blood and Endocrinology Center, St. Petersburg, Russia aaRSPC Cardiology, Minsk, Belarus abNSC 'Institute of Cardiology named after N.D. Strazhesko' of NAMS, Kiev, Ukraine acEmergency Hospital of Bucharest, Romania adUniversity Hospital Saint Anna, Sofia, Bulgaria aeDr Peter Drzai Hospital, Ljubljana, Slovenia afUniversity Hospital Center Zagreb, Croatia agClinic for Internal Medicine InterMedic, Nis, Serbia ahCardiology Department, Asklepeion General Hospital, Athens, Greece aiNicosia General Hospital, Nicosia, Cyprus ajIstanbul University Cerrahpa┼ča School of Medicine, Istanbul, Turkey akHasharon Hospital - Rabin Medical Center, Petach-Tikva, Israel alBeijing Xuanwu Hospital amSecond Affiliate Hospital, Beijing University anMilitary General Hospital, China aoHospital Clinic. University of Barcelona, Barcelona, Spain apUniversity of Cambridge, Cambridge aqOxford University Hospital NHS Trust, Oxford, United - - 2014
The SBP values to be achieved by antihypertensive therapy in order to maximize reduction of cardiovascular outcomes are unknown; neither is it clear whether in patients with a previous cardiovascular event, the optimal values are lower than in the low-to-moderate risk hypertensive patients, or a more cautious blood pressure (BP) ...
Zanchetti Alberto A aIstituto Auxologico Italiano bUniversità di Milano, Milan, Italy cFuWai Hospital and Cardiovascular Institute dBeijing Hypertension League Institute, Beijing, China eUniversità Milano-Bicocca fOspedale San Gerardo, Milan, Italy gOslo University Hospital, Oslo, Norway hUniversity of Valencia, Madrid, Spain iMedical University of Gdansk, Gdansk, Poland jUniversity of Glasgow, Glasgow, UK kLund University, Scania University Hospital, Malmo, Sweden lTallinn University of Technology, Tallinn, Estonia mEuropean Hospital Georges Pompidou, Paris, France nUniversità di Brescia, Spedali Civili, Brescia, Italy oBeijing Anzhen Hospital, Beijing pShanghai Hypertension Institute, Shanghai, China qComplutense University rHospital 12 de Octubre sHospital Clínico San Carlos, Madrid, Spain tCentro Hospitalar de Entre o Douro e Vouga, E.P.E., Portugal uNephrology and Hypertension, University Hospital, Erlangen, Germany vUniversity Hospital of Lausanne, Lausanne, Switzerland wMedical University of Lodz, Lodz, Poland xCharles University Medical School I and Thomayer Hospital, Prague, Czech Republic ySt. Imre University Teaching Hospital, Budapest, Hungary zAlmazov Federal Heart, Blood and Endocrinology Center, St. Petersburg, Russia aaRSPC Cardiology, Minsk, Belarus abNSC 'Institute of Cardiology named after N.D. Strazhesko' of NAMS, Kiev, Ukraine acEmergency Hospital of Bucharest, Bucharest, Romania adUniversity Hospital Saint Anna, Sofia, Bulgaria aeDr Peter Drzai Hospital, Ljubljana, Slovenia afUniversity Hospital Center Zagreb, Zagreb, Croatia agClinic for Internal Medicine InterMedic, Nis, Serbia ahCardiology Department, Asklepeion General Hospital, Athens, Greece aiNicosia General Hospital, Nicosia, Cyprus ajIstanbul University Cerrahpa┼ča School of Medicine, Istanbul, Turkey akHasharon Hospital - Rabin Medical Center, Petach-Tikva, Israel alBeijing Xuanwu Hospital amSecond Affiliate Hospital, Beijing University anMilitary General Hospital, Beijing, China aoHospital Clinic, University of Barcelona, Barcelona, Spain apUniversity of Cambridge, Cambridge aqOxford University Hospital NHS Trust, Oxford, - - 2014
It is well established by a large number of randomized controlled trials that lowering blood pressure (BP) and low-density lipoprotein cholesterol (LDL-C) by drugs are powerful means to reduce stroke incidence, but the optimal BP and LDL-C levels to be achieved are largely uncertain. Concerning BP targets, two hypotheses are ...
Fleury Camila A CA Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Alameda Octávio Pinheiro Brisolla, 9-75, Bauru, SP, 17012-901, - - 2014
Epinephrine is considered the gold standard vasoconstrictor for hypertensive patients, but few studies report felypressin's effects. The present study aimed to analyze and compare the effects of these two vasoconstrictors, injected by the intravenous route, on the arterial pressure of normotensive, hypertensive and atenolol-treated hypertensive rats. The hypertension model was ...
Farahmand Dan D Hydrocephalus Research Unit, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, - - 2014
The association between intracranial pressure (ICP) and different shunt valve opening pressures in relation to body positions is fundamental for understanding the physiological function of the shunt. To analyse the ICP and ICP wave amplitude (AMP) at different shunt settings and body positions in patients with hydrocephalus. In this prospective ...
Shahidi S S Department of Vascular Surgery, Regional Hospital Slagelse, Region Zealand, - - 2014
The aim of this study was to validate a Stump Pressure(SP) of 40 mmHg(mean) as the cut off threshold for shunting during carotid endarterectomy (CEA) . A prospective analysis of recently symptomatic carotid stenosis patients undergoing CEA (Fast Track) under GA. An arbitrary cut-offthreshold of 40 mm Hg (mean) was ...
Olszanecka Agnieszka A I Department of Cardiology, Invasive Electrocardiology and Hypertension, Jagiellonian University Medical College, University, Krakow, Poland. Electronic address: - - 2014
We investigated the association between metabolic syndrome (MS), its components and the presence of subclinical organ damage in hypertensive perimenopausal women. 152 women with newly diagnosed, untreated arterial hypertension (mean age 51.0±3.5 years) were included in the study. In all subjects anthropometrical measurements, 24-hr blood pressure monitoring, echocardiographic examination, and ...
Vongpatanasin Wanpen W Hypertension Section, Cardiology Division, University of Texas Southwestern Medical Center, - - 2014
Resistant hypertension-uncontrolled hypertension with 3 or more antihypertensive agents-is increasingly common in clinical practice. Clinicians should exclude pseudoresistant hypertension, which results from nonadherence to medications or from elevated blood pressure related to the white coat syndrome. In patients with truly resistant hypertension, thiazide diuretics, particularly chlorthalidone, should be considered as ...
Pereira Telmo T aPolytechnic Institute of Coimbra, ESTES, Department of Cardiopneumology bInstitute of Cardiovascular Research, Coimbra, - - 2014
Arteries are the target, the place, and the common denominator of cardiovascular diseases; hence, study of arterial function is of greatest importance in clinical practice. The aim of this study was to evaluate the accuracy of carotid pulse wave analysis using the new version of the Complior device - the ...
Werndle Melissa C MC Department of Neurosurgery, St. George's University of London, London, United - - 2014
Idiopathic intracranial hypertension is a difficult condition to manage. We present a novel treatment that substantially improved the headaches and reduced admissions and shunt revision surgery in a patient. We inserted a ventriculoperitoneal shunt, performed subtemporal craniectomies, and instructed our patient to apply different sized headbands to allow her to ...
Frishman William H WH Department of Medicine, New York Medical College, Valhalla, NY, 10595, USA, - - 2014
Resistant systemic hypertension in patients is defined as the inability to control blood pressure despite taking at least three antihypertensive drugs, one of which is a diuretic. Two nonpharmacologic approaches are being evaluated in resistant hypertensive patients. First, the Rheos® Baroreflex Hypertension Therapy system is an implantable device that activates ...
Taylor Chloe E CE School of Science and Health, University of Western Sydney, - - 2014
The arterial baroreflex is critical to both short and long-term regulation of blood pressure. However, human baroreflex research has been largely limited to the association between blood pressure and cardiac period (or heart rate) or indices of vascular sympathetic function. Over the past decade, emerging techniques based on carotid ultrasound ...
Yang Diya D Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing, - - 2014
Purpose. To examine the influence of experimentally reduced cerebrospinal fluid pressure (CSFP) on retinal nerve fiber layer (RNFL) thickness and neuroretinal rim area of the optic nerve head. Methods. The experimental study included 9 monkeys which underwent an implantation of a lumbar-peritoneal CSF shunt. In the study group (n= 4 ...
Gray Vicki L VL Department of Physical Therapy and Rehabilitation Sciences, University of Maryland, Baltimore, MD 21201, - - 2014
Knowing the reliability of the center of pressure (COP) is important for interpreting balance deficits post-stroke, especially when the balance deficits can necessitate the use of short duration trials. The novel aspect of this reliability study was to examine the center of pressure measures using two adjacent force platforms between ...
Kim Joong-Seok JS Department of Neurology, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 505, Banpo-dong, Seocho-gu, Seoul, 137-701, South Korea, - - 2014
Cognitive dysfunction constitutes a major non-motor manifestation of Parkinson disease (PD), but the mechanisms remain incompletely understood. Neurocirculatory abnormalities such as supine hypertension (SH) and orthostatic hypotension (OH), white matter hyperintensities upon magnetic resonance imaging, and dementia are inter-related in PD, even in patients with early, levodopa-untreated disease. These abnormalities ...
Mathis Keisa W KW Department of Physiology and Biophysics, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS, 39216-4505, - - 2014
One in every three adults in the United States has hypertension, and the underlying cause of most of these cases is unknown. Therefore, it is imperative to continue the study of mechanisms involved in the pathogenesis of hypertension. Decades ago, studies speculated that elements of an autoimmune response were associated ...
Prabhakaran Shyam - - 2014
This review focuses on the recommendations for management of hypertension, dyslipidemia, diabetes mellitus, diet, physical activity, and lifestyle choices commonly encountered in neurologic practice. Specific studies, including those relevant to lipid targets, blood pressure targets, and adherence to medications after stroke, are reviewed. In addition to traditional risk factors such ...
Kim Ju-Hyun JH Laboratory of Health Science and Nanophysiotherapy, Department of Physical Therapy, Graduate School, Yongin University, Republic of - - 2014
[Purpose] Brachial-ankle pulse wave velocity (BaPWV), which has been reported as an index of arterial stiffness, is very closely related to cardiovascular risk factors. A high BaPWV indicates high cardiovascular risk. However, BaPWV and pressure waveforms after stroke are not fully understood. [Methods] BaPWV was measured in thirty-two subjects (twenty-two ...
Godfrey G E P GE Department of Anaesthesia, Hillingdon Hospital, London, - - 2014
Current guidelines for intra-operative fluid management recommend the use of increments in stroke volume following intravenous fluid bolus administration as a guide to subsequent fluid therapy. To study the physiological premise of this paradigm, we tested the hypothesis that healthy, non-starved volunteers would develop an increment in their stroke volume ...
Sui Binbin B Radiology Department, Beijing Neurosurgical Institute, Affiliated Beijing Tiantan Hospital, Capital Medical University, Beijing, PR - - 2014
Histopathological studies have shown significant differences in plaque components and surface conditions between upstream and downstream of the stenosis. It can be deduced that the flow status near the plaques is different from the flow status at the upstream side, stenosis center, or downstream side of the plaque. To study ...
Swallow D M A DM University of Aberdeen, Aberdeen, - - 2014
Infusion tests are important tools to assess cerebrospinal fluid (CSF)dynamics used in the preoperative selection of patients for shunt surgery, or to predict the scope of improvement from shunt revision. The aim of this study was to assess the repeatability of the key quantitative parameters describing CSF dynamics that are ...
Niemuth Jennifer N JN College of Veterinary Medicine, North Carolina State University, Raleigh, NC, - - 2014
A 34-year-old western lowland gorilla presented with peracute blindness. Clinical evaluation, diagnostic imaging, laboratory analyses, blood pressure measurements, and necropsy were performed. The clinical and postmortem findings supported malignant hypertension. We describe a case of naturally occurring hypertensive encephalopathy and retinopathy in a gorilla.
Wang Ji-Hung JH Division of Cardiology, School of Medicine, Tzu Chi University, Hualien, Taiwan; Buddhist Tzu Chi General Hospital, School of Medicine, Tzu Chi University, Hualien, - - 2014
Osteoprotegerin (OPG) has been implicated in the process of vascular stiffness. The aim of this study was to evaluate the relationship between fasting serum OPG concentration and carotid-femoral pulse wave velocity (c-f PWV) in hypertensive patients. Fasting blood samples were obtained from 184 participants with or without hypertension. c-f PWV ...
Williams Michael A MA From The Sandra and Malcolm Berman Brain & Spine Institute, Adult Hydrocephalus Center, and Center for Gait and Mobility, Sinai Hospital of Baltimore, - - 2014
Idiopathic normal-pressure hydrocephalus (iNPH) is a reversible syndrome of gait impairment, dementia, and incontinence that affects persons over 65 years of age.(1) Currently, the only effective treatment is surgical implantation of a shunt(2); however, the need for pharmacologic adjunctive treatments was noted at the 2005 NIH workshop on hydrocephalus.(3.)
Yun Lin L Department of Cardiology, Qianfoshan Hospital of Shandong Province, Shandong - - 2014
The aim of this study was to evaluate the correlations between microalbuminuria (MAU) and endothelial function in hypertensive patients with carotid plaques (CP). A total of 71 hypertensive patients with CP (CP group) and 20 healthy people as normal controls (NC group) were enrolled in this study. The CP group ...
McClain Jonathon L JL Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI 48824, - - 2014
Hypertension causes cerebral artery remodeling and increases the risk of stroke. Renin angiotensin system blockade during the development of hypertension has therapeutic effects even after treatment withdrawal. Mineralocorticoid receptor (MR) activation has been implicated in artery remodeling and impaired endothelial function. The possibility that there is a critical therapeutic window ...
Pergola Pablo E PE Department of Medicine, University of Texas Health Sciences Center at San Antonio and Renal Associates PA, San Antonio, - - 2014
Lowering blood pressure (BP) after stroke remains a challenge, even in the context of clinical trials. The Secondary Prevention of Small Subcortical Strokes (SPS3) BP protocol, BP management during the study, and achieved BPs are described here. Patients with recent symptomatic lacunar stroke were randomized to 1 of 2 levels ...
Tibazarwa Kemi B KB The Hatter Institute for Cardiovascular Research, Department of Medicine, Faculty of Health Sciences, The University of Cape Town, Cape Town, South Africa; Department of Cardiovascular Medicine, Muhimbili National Hospital, - - 2014
The past 2 decades have seen a considerable global increase in cardiovascular disease, with hypertension remaining by far the most common. More than one-third of adults in Africa are hypertensive; as in the urban populations of most developing countries. Being a condition that occurs with relatively few symptoms, hypertension remains ...
Bath Philip M W PM Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, Nottingham, - - 2014
High blood pressure is common during the acute phase of stroke and is associated with a poor outcome. However, the management of high blood pressure remains unclear. The 'Efficacy of Nitric Oxide in Stroke' trial tested whether transdermal glyceryl trinitrate, a nitric oxide donor that lowers blood pressure, is safe ...
Byrd James Brian JB Division of Cardiovascular Medicine, Department of Medicine, University of Michigan, 20-209W, North Campus Research Complex 2800 Plymouth Road, Ann Arbor, MI, 48109-2800, USA, - - 2014
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) recommended a thiazide-like diuretic, alone or in combination with other antihypertensive drug classes, as initial therapy for hypertension. JNC 7, however, did not specify preferred combinations. The Avoiding Cardiovascular Events ...
Salma Asem A Department of Neurosurgery, Illinois Neurological Institute, University of Illinois College of Medicine at Peoria, 530 NE Glen Oak, Peoria, IL, 61637, USA, - - 2014
The theme of this paper is to outline that the genesis of normal pressure hydrocephalus (NPH) is governed by the intracranial pressure (ICP) homeostatic principle. The development of this new concept is based mainly on rethinking the well-known Monro-Kellie doctrine in the way that ICP homeostasis mechanism is not only ...
Fischer Urs U Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, - - 2014
It is often assumed that blood pressure increases acutely after major stroke, resulting in so-called post-stroke hypertension. In view of evidence that the risks and benefits of blood pressure-lowering treatment in acute stroke might differ between patients with major ischaemic stroke and those with primary intracerebral haemorrhage, we compared acute-phase ...
Tang Lingyan L aDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou bDepartment of Cardiology, the First Affiliated Hospital of China Medical University, Shenyang, Liaoning Province, China *L.T. and T.X. contributed equally to this - - 2014
The purpose of this study was to evaluate the effect of hypertension and alcohol drinking on stroke incidence and whether alcohol drinking would increase the risk of stroke in hypertension participants among Inner Mongolians. A prospective cohort study from June 2003 to July 2012 was conducted among 2535 people aged ...
Wohlfahrt Peter P aCenter for Cardiovascular Prevention of the First Faculty of Medicine, Charles University and Thomayer Hospital, Prague bInternational Clinical Research Center, St Ann's University Hospital, Brno cDepartment of Preventive Cardiology, Institute for Clinical and Experimental Medicine, Prague d2nd Department of Internal Medicine, Charles University, Center for Hypertension, Pilsen, Czech Republic eDepartment of Pharmacology, Georges Pompidou European Hospital, INSERM U970 and Paris University Descartes, Paris, France fDepartment of Cardiology and Angiology, First Faculty of Medicine, Charles University, Prague, Czech - - 2014
Aortic stiffness is increased in lacunar stroke. The precise mechanism linking aortic stiffness to symptomatic lacunar stroke is not well understood. The aim of this study was to compare the effects of aortic stiffness, carotid stiffness, central blood pressure, and cerebrovascular resistance on carotid flow pulsatility according to stroke subtype. ...
Johnson Rebecca C RC University of California, San - - 2014
Patients with pulmonary hypertension associated with congenital heart disease survive longer with preserved right ventricular (RV) function compared to those with primary pulmonary hypertension. The purpose of this study was to test the hypothesis that superior RV performance can be demonstrated, at baseline and when challenged with increased RV afterload, ...
Mandraffino G G Department of Clinical and Experimental Medicine, University of Messina, Messina, - - 2014
We investigated whether different degrees of hypertension-related cardiovascular involvement are associated with changes in circulating proangiogenic hematopoietic cell (PHC) numbers and/or phenotypes and/or in the PHC redox system in hypertensive individuals with isolated arterial stiffening (AS) hypertensives or with both carotid intima-media thickening and left ventricular hypertrophy (LVH) hypertensives. We ...
Buratti Laura L Neurological Clinic, Marche Polytechnic University, Ancona, - - 2014
The aim of this study was to evaluate the relationship between arterial blood pressure (BP) variability during the acute phase and the 3-month outcome in ischemic stroke patients with internal carotid artery (ICA) occlusion. At least 10 BP measurements during the first 48h after stroke onset were obtained in 89 ...
Powers William J WJ From the Department of Neurology (W.J.P.), University of North Carolina School of Medicine, Chapel Hill; Clinical Trials Statistics and Data Management Center (W.R.C.), University of Iowa College of Public Health, Iowa City; Departments of Neurological Surgery (R.L.G., C.P.D.), Radiology (R.L.G., T.O.V., C.P.D.), and Neurology (T.O.V., C.P.D.), Washington University School of Medicine, St. Louis, MO; and the Department of Neurology (H.P.A.), University of Iowa Carver School of Medicine, Iowa - - 2014
To determine whether strict blood pressure (BP) control is the best medical management for patients with symptomatic carotid artery occlusion and hemodynamic cerebral ischemia. In this prospective observational cohort study, we analyzed data from 91 participants in the nonsurgical group of the Carotid Occlusion Surgery Study (COSS) who had recent ...
Gottesman Rebecca F RF From the Department of Neurology (R.F.G.), Johns Hopkins University School of Medicine, Baltimore, MD; and The George Institute for Global Health (J.C.), Sydney, - - 2014
Classical neurologic teaching suggests that a higher cerebral systemic blood pressure (BP) be targeted for individuals with occlusive carotid disease, in order to improve cerebral perfusion through collaterals. This conflicts, however, with observational, population-based studies and clinical trials supporting better outcomes associated with lower BPs. In this issue of Neurology®, ...
Hart Michael Gavin MG Academic Division of Neurosurgery, Departments of Clinical Neurosciences and Neurosurgery, Addenbrooke's Hospital, Cambridge, - - 2014
Introduction: Slit ventricle syndrome remains a complex entity presenting a considerable challenge to treat successfully. This study aims to demonstrate the application of dual intracranial pressure (ICP) and infusion studies together with the novel shunt occlusion test in both a diagnostic and therapeutic role. Case Report: An 8-year-old child had ...
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