Search Results
Results 201 - 250 of 699
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Andersson K - - 2012
INTRODUCTION: Infusion tests are used to diagnose and select patients with idiopathic normal pressure hydrocephalus (INPH) for shunt surgery. The test characterizes cerebrospinal fluid dynamics and estimates parameters of the cerebrospinal fluid system, the pressure-volume index (PVI) and the outflow conductance (C(out) ). The Oscillating Pressure Infusion (OPI) method was ...
Bijker Jilles B - - 2012
PURPOSE: A stroke is an uncommon but potentially devastating complication after surgery. Although hypoperfusion is often mentioned as a possible cause of a perioperative stroke, a thorough investigation is needed into the role of intraoperative and/or postoperative hypotension in the occurrence and development of perioperative cerebral ischemia. In this review ...
Lackland Daniel T - - 2012
PURPOSE OF REVIEW: Hypertension has been recognized for decades as a major factor for stroke, with observational epidemiologic studies clearly identifying the increased stroke risks with blood pressure (BP) levels and randomized controlled clinical trials providing evidence of stroke risk reduction with lower BPs. Hypertension treatment and management guidelines, the ...
Hirata Kozo - - 2012
OBJECTIVES:: The aim of this study was to examine the utility of the generalized transfer function (GTF) and the late systolic shoulder of the radial pressure waveform (SBP2) for estimating seated central systolic blood pressure (c-SBP) and seated c-augmentation index (c-AIx). METHODS:: In 199 participants (182 cardiovascular disease patients and ...
Müller Jan - - 2013
Carotid to femoral pulse wave velocity (PWV) is associated with an increase in cardiovascular morbidity and all-cause mortality. Noninvasive approach has made this method applicable for the examination of larger populations. This study aimed to obtain reference values of PWV measured with the Vicorder device. PWV was obtained using the ...
Mattei Tobias A - - 2012
Object Although several improvements have been observed in the past few years in shunt technology, currently available systems still present several associated problems. Among these, overdrainage along with its complications remains one of the great challenges for new shunt designs. To address the so-called siphoning effect, the authors provide a ...
Czosnyka Zofia - - 2012
Object Independent testing of hydrocephalus shunts provides information about the quality of CSF drainage after shunt implantation. Moreover, hydrodynamic parameters of a valve assessed in the laboratory create a comparative pattern for testing of shunt performance in vivo. This study sought to assess the hydrodynamic parameters of the Certas valve, ...
Selwaness Mariana - - 2012
Intraplaque hemorrhage (IPH) is a characteristic of the vulnerable atherosclerotic plaque that has been associated with ischemic stroke. Not much is known about determinants of IPH. We studied whether blood pressure parameters are associated with presence of IPH. Within the framework of a prospective population-based cohort study, The Rotterdam Study, ...
Wang Ji-Guang - - 2012
According to the 4th National Nutrition and Health Survey in 2002, the prevalence of hypertension in China was 18.8%. Despite that, the treatment rate among hypertensive patients was 82%, the control rate remained low in persons with hypertension (6%), because of the low awareness in general (30%) and the low ...
Duivenvoorden Raphaël - - 2012
Cholesteryl ester transfer protein (CETP)-inhibiting drugs effectively raise HDL cholesterol. In 2007, the CETP inhibitor torcetrapib unexpectedly showed increased fatality and cardiovascular events, possibly related to increased blood pressure and aldosterone levels caused by torcetrapib. Since then, novel CETP inhibiting drugs have been investigated. This review will discuss the safety ...
Bragin Denis E DE Department of Neurosurgery, University of New Mexico School of Medicine, 1 University of New Mexico MSC10-5615, Albuquerque, NM 87131, USA. - - 2013
Recently, we showed that decreasing cerebral perfusion pressure (CPP) from 70 mm Hg to 50 mm Hg and 30 mm Hg by increasing intracranial pressure (ICP) with a fluid reservoir induces a transition from capillary (CAP) to microvascular shunt (MVS) flow in the uninjured rat brain. This transition was associated ...
Li Yue - - 2012
PURPOSE.: Wave intensity (WI) is a set of new hemodynamic indexes (W(1) , W(2) , and NA) based on the calculation of (dp/dt) × (dv/dt) on any artery. We assessed the value of carotid WI analysis for differentiating nonobstructive hypertrophic cardiomyopathy (NOHCM) from left ventricular hypertrophy secondary to hypertension (LVHSH). ...
Aihara Yasuo - - 2012
Object The CSF shunt valve is a medical device whose main function is to regulate intracranial pressure and drain excess CSF. The authors have developed a new therapeutic method for treating hydrocephalus, namely the tandem shunt valve system, which has the potential of flexibly controlling the CSF flow rate and ...
Kaliaperumal Chandrasekaran - - 2012
OBJECTIVE: We describe three cases of delayed development of intracranial hypertension post surgical treatment of intracranial arachnoid cyst. It is rare occurrence and the management may pose a challenge.The aetiopathogensis of this condition is described with a review of literature. METHODS: A retrospective and prospective analysis of three male patients, ...
Hadjiev Dimiter I - - 2012
A transient elevated arterial blood pressure is common in acute ischemic stroke and is often associated with a poor prognosis. The underlying mechanisms of blood pressure elevation are not well understood and its management is still unresolved. This article focuses on pathophysiology and management of elevated blood pressure in acute ...
Kerry Sally M SM Centre for Primary Care and Public Health, Barts and The London School of Medicine and Dentistry, Queen Mary, University of London, London, UK. - - 2013
Adequate control of blood pressure reduces the risk of recurrent stroke. We conducted a randomized controlled study to determine whether home blood pressure monitoring with nurse-led telephone support would reduce blood pressure in patients with hypertension and a history of stroke. We recruited 381 participants (mean age 72 years) from ...
Vaclavik Jan - - 2012
AIMS: There are currently limited data about whether the effect of spironolactone in patients with resistant arterial hypertension depends on baseline blood pressure and the presence of a secondary cause of hypertension. METHODS: Patients with office systolic blood pressure (BP) >140 mmHg or diastolic BP >90 mmHg, despite treatment with at ...
Yamamoto Yasumasa - - 2012
BACKGROUND: The optimal management of high blood pressure (BP) during the acute stage of stroke has yet to be established. To test the extent to which BP can be lowered without causing adverse effects and to determine the safety or efficacy of administration of antihypertensive agents in acute ischemic stroke, ...
Hasty Alyssa H - - 2012
Hypertension occurs in approximately 30% of individuals in Western populations and is known to be a major cause of stroke, heart failure, and myocardial infarction. Despite this, the molecular etiology of hypertension remains poorly understood. In this issue of the JCI, Young et al. show that endoplasmic reticulum (ER) stress ...
Park Eun-Hyoung - - 2012
Object The pathophysiology of normal pressure hydrocephalus (NPH), and the related problem of patient selection for treatment of this condition, have been of great interest since the description of this seemingly paradoxical condition nearly 50 years ago. Recently, Eide has reported that measurements of the amplitude of the intracranial pressure ...
Tsivgoulis Georgios - - 2012
Poststroke hypertension is a common complication of acute cerebral ischemia (ACI) occurring in up to 80% of acute ischemic stroke (AIS) patients.(1) Despite its high prevalence, the optimal management of arterial hypertension during the acute stroke stage has not been established and remains an issue of long-lasting debate and little ...
Cheng Kevin - - 2012
BACKGROUND:: Central blood pressure is a determinant of cardiovascular outcome; however, it can be described by parameters other than systolic and diastolic pressure with central augmentation index (AIx) often utilized. Although generally considered as determined by peripheral pressure wave reflection, not all data are consistent with this interpretation of AIx. ...
Chakor Rahul T - - 2012
Cerebral venous sinus thrombosis (CVT) is a rare cerebrovascular disease with variable presentation. CVT rarely causes hydrocephalus. Communicating hydrocephalus due to CVT is extremely rare. We describe a patient of CVT presenting with chronic headache and communicating hydrocephalus. The patient was successfully treated with ventriculoperitoneal (VP) shunt. A 40 year ...
Dave Jaydev K - - 2012
Effective animal models are needed to evaluate the feasibility of new techniques to assess portal hypertension (PH). Here we developed 2 canine models of acute PH by increasing intrasinusoidal resistance and by increasing the portal vein (PV) flow volume to test the efficacy of a noninvasive technique to evaluate PH. ...
Fiala Jens - - 2012
An implantable sensor system for long-term monitoring of blood pressure is realized by taking advantage of the correlation between pulse transit time and blood pressure. The highly integrated implantable sensor module, fabricated using MEMS technologies, uses 8 light emitting diodes (LEDs) and a photodetector on chip level. The sensor is ...
Kaddumukasa Martin M Makerere University, College of Health Sciences, Kampala, - - 2012
Little is known about the frequency of hypertension and related knowledge in Africans who have had a stroke. The objective of this study was to determine the frequency of hypertension, its control, and associated knowledge among patients with and without a history of stroke at Uganda's main referral hospital. Subjects ...
Ntaios G - - 2012
OBJECTIVE:Previous research suggested that proper blood pressure (BP) management in acute stroke may need to take into account the underlying etiology. METHODS:All patients with acute ischemic stroke registered in the ASTRAL registry between 2003 and 2009 were analyzed. Unfavorable outcome was defined as modified Rankin Scale score >2. A local ...
Carroll John L JL Division of Pediatric Pulmonary Medicine, Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, 1 Children's Way, Little Rock, AR 72202, United States. - - 2013
Carotid body (CB) chemoreceptors transduce low arterial O(2) tension into increased action potential activity on the carotid sinus nerves, which contributes to resting ventilatory drive, increased ventilatory drive in response to hypoxia, arousal responses to hypoxia during sleep, upper airway muscle activity, blood pressure control and sympathetic tone. Their sensitivity ...
Hayoz Daniel - - 2012
J Clin Hypertens (Greenwich). 2012;14:773-778. ©2012 Wiley Periodicals, Inc. Postmenopausal women are at greater risk for hypertension-related cardiovascular disease. Antihypertensive therapy may help alleviate arterial stiffness that represents a potential modifiable risk factor of hypertension. This randomized controlled study investigated the difference between an angiotensin receptor blocker and a calcium ...
Idzenga Tim - - 2012
To noninvasively estimate the blood pressure continuously in the common carotid artery (CCA), we obtained the distension waveform of the CCA from seven healthy volunteers and 20 hypertensive patients using radio-frequency ultrasound. Consequently, it was calibrated by the mean and diastolic pressure measured in the finger artery and compared with ...
Elistratova E I - - 2012
We studied the relationships between the blood serum levels of human leukemia differentiation factor HLDF, idiotypic and anti-idiotypic antibodies to HLDF, and clinical indicators of cardiovascular function in apparently healthy individuals and patients with essential hypertension and cerebral hypertensive crisis. Markedly reduced HLDF levels and anti-HLDF antibody titers were found ...
Pinto Fernando Campos Gomes - - 2012
Patients with hydrocephalus and risk factors for overdrainage may be submitted to ventricular shunt (VS) implant with antisiphon device. The objective of this study was to prospectively evaluate for two years the clinical and tomographic results of the implant of fixed-pressure valves with antisiphon device SPHERA® in 35 adult patients, ...
Jain Anil Kumar - - 2012
: The potential for fluid overload in large-volume liposuction is a source of serious concern. Fluid management in these patients is controversial and governed by various formulas that have been advanced by many authors. Basically, it is the ratio of what goes into the patient and what comes out. Central ...
Aksakal Devrim - - 2012
The impact of a capnoperitoneum on the known blood pressure (BP) difference of the upper and lower limb was studied in piglets. Eleven German Landrace piglets (body weight, 4.3-7.4 kg; mean body weight, 6.2 kg) were studied. Arterial lines were placed in the right carotid and right femoral artery for ...
Pieterse Chiné - - 2012
Hypertension and obesity are serious health burdens in sub-Saharan Africa. Urbanized Africans seem to be more susceptible to the development of these diseases than Caucasians. Current research suggests that leptin may be an important contributor to the development of hypertension and atherosclerosis. The aim of this study was to investigate ...
Kang Byeong-Teck - - 2012
Arterial hypertension is a major risk factor for ischemic stroke. However, the management of preexisting hypertension is still controversial in the treatment of acute stroke in hypertensive patients. The present study evaluates the influence of preserving hypertension during focal cerebral ischemia on stroke outcome in a rat model of chronic ...
Cyrous Alma - - 2012
Stroke is a common, potentially devastating disease with potential high morbidity and mortality. Recognition at the onset of acute ischemic stroke is pivotal to changing outcomes such as intravenous thrombolysis. Stroke monitoring is a burgeoning field with various methods described and newer devices that aid in detecting acute or worsening ...
Rademaker Miriam T - - 2012
BACKGROUND: -The (pro)renin receptor (P)RR is implicated in blood pressure regulation and the pathophysiology of heart failure. The effects of (P)RR blockade in heart failure have not previously been investigated. METHODS AND RESULTS: -Eight sheep received on two separate days a vehicle control and incremental intravenous boluses of a (P)RR ...
Johansen Nanna B - - 2012
Diabetes is associated with increased brachial and central blood pressure and aortic stiffness. We examined the effect of intensive multifactorial treatment in general practice on indices of peripheral and central hemodynamics among patients with screen-detected diabetes. As part of a population-based screening and intervention study in general practice, 1,533 Danes ...
Buchholz Stefan - - 2012
High transvalvular pressure gradients following aortic valve replacement can be caused by several possible mechanisms. We present the case of an elderly woman with an elevated pressure gradient across an aortic valve bioprosthesis in the setting of complete heart block. After consideration of the presence of complete heart block, the ...
Patarroyo Sully Xiomara Fuentes - - 2012
Persistent controversy exists as to whether there are worthwhile beneficial effects of early, rapid lowering of elevated blood pressure (BP) in acute stroke. Elevated BP or 'hypertension' (i.e. systolic >140 mmHg) is common in stroke, especially in patients with pre-existing hypertension and large strokes, due to variable 'autonomic stress' and ...
Shafei Mohammad Naser - - 2012
The cuneiform nucleus (CnF) is a sympathoexcitatory area involved in the central cardiovascular regulation. Its role in the maintaining vasomotor tone has, however, not yet been clarified. In the present study the effects of cobalt chloride (CoCl(2)) a nonselective synapse blocker and NMDA and non-NMDA glutamate receptors on resting mean ...
Garcia Anthony G - - 2012
Diastolic heart failure (HF) accounts for up to 50% of all HF admissions, with hypertension being the major cause of diastolic HF. Hypertension is characterized by left ventricular (LV) hypertrophy (LVH). Proinflammatory cytokines are increased in LVH and hypertension, but it is unknown if they mediate the progression of hypertension-induced ...
Garofalo F - - 2012
Using morphological and physiological approaches we provided, for the first time, a structural and functional characterization of Carassius auratus L. heart. Besides to the classical four chambers, i.e. sinus venosus, atrium, ventricle, bulbus, we described two distinct structures corresponding to the atrio-ventricular (AV) region and the conus arteriosus. The atrium ...
Kapp Suzanne - - 2012
Rationale  This paper reports an initiative which promoted evidence-based practice in pressure risk assessment and management among home nursing clients in Melbourne, Australia. Aim and objectives  The aim of this study was to evaluate the introduction and uptake of the Australian Wound Management Association Guidelines for the Prediction and Prevention ...
Fitzgerald Meshann - - 2012
To compare the diagnostic utility of Doppler echocardiography-derived tricuspid regurgitant jet velocity (TRV) ≥2.5 m/s to right heart catheterization (RHC) in defining pulmonary hypertension (PH) in adult patients with sickle cell disease (SCD). This is a retrospective chart review of adults with SCD who had a TRV ≥2.5 m/s and ...
Rafique Asim M - - 2012
Multiple echocardiographic criteria are routinely used for the estimation of left heart filling pressures. We assessed the predictive value of various echocardiographic parameters to estimate the left heart filling pressure and proposed a simplified approach for its evaluation. We collected the clinical, echocardiographic, and invasive hemodynamic data from 93 patients ...
Barnett Christopher F - - 2012
Pulmonary hypertension (PH) is characterized hemodynamically by significantly elevated pulmonary artery pressure, which if sustained can result in clinical deterioration due to progressive right-sided heart failure and death. Establishing the etiology of PH in a patient before treatment is imperative. Effective evidence-based therapeutic agents for treating PH have been developed. ...
Hannemann Anke - - 2012
Objective: The prevalence of primary aldosteronism in unselected hypertensive patients is currently unknown. We investigated the frequency of positive screening results for primary aldosteronism based on the aldosterone-to-renin ratio (ARR) in hypertensive subjects aged 30-79 years from two German epidemiological studies. We further examined the frequency of positive screening results ...
Kichukov Kostadin N - - 2012
Arterial hypertension is the most common chronic cardiovascular disease affecting about 25% of the adult population. Meta-analyses have demonstrated a linear relationship between blood pressure and the risk of cardiovascular events. Resistant hypertension defined as failure to reach blood pressure targets despite treatment with three antihypertensive drugs including a diuretic ...
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