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Results 51 - 100 of 1603
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Nishida Yasuhiro - - 2013
Sympathetic nerve activity in essential hypertension, which accounts for 90% of all hypertension cases, is in general thought to be elevated regardless of whether there is salt sensitivity or insensitivity. The cause is thought to be an abnormality in the sympathetic center. On the other hand, neuronal nitric oxide synthase-expressing ...
Freet Christopher S - - 2013
There is a large amount of evidence linking obstructive sleep apnea (OSA), and the associated intermittent hypoxia that accompanies it, with the development of hypertension. For example, cross-sectional studies demonstrate that the prevalence of hypertension increases with the severity of OSA (Bixler et al., 2000; Grote et al., 2001) and ...
Reineke Kai - - 2013
High pressure combined with elevated temperatures can produce low acid, commercially sterile and shelf-stable foods. Depending on the temperature and pressure levels applied, bacterial endospores pass through different pathways, which can lead to a pressure-induced germination or inactivation. Regardless of the pathway, Bacillus endospores first release pyridine-2,6-dicarboxylic acid (DPA), which ...
Ettinger Keren - - 2013
The effect of the venom of the Chactoid family of scorpions on blood pressure was scantly investigated and was addressed in the present study using the venom of the Israeli scorpion, Scorpio maurus palmatus. Blood pressure in rats was monitored via cannulated femoral artery, while venom and toxins were introduced ...
Jing Xiao-Kun - - 2013
Gable roof buildings are widely used in industrial buildings. Based on wind tunnel tests with rigid models, wind pressure distributions on gable roof buildings with different aspect ratios were measured simultaneously. Some characteristics of the measured wind pressure field on the surfaces of the models were analyzed, including mean wind ...
Mancia Giuseppe - - 2013
The sympathetic nervous system participates in the development and progression of the essential hypertensive state, as shown by increased circulating plasma levels of the adrenergic neurotransmitter norepinephrine, elevated norepinephrine spillover rate, and augmented sympathetic nerve traffic discharge detected in the high blood pressure state. In addition, the sympathetic overdrive participates ...
Yang Yuyou - - 2013
This paper focuses on the face stability analysis of Double-O-Tube shield tunnel. This kind of analysis is significant to ensure the safety of workers and reduce the influence on the surrounding environment. The key point of the stability analysis is to determine the supporting pressure applied to the face by ...
Harlan Shannon M SM Department of Pharmacology, University of Iowa Carver College of Medicine, Iowa City, IA, - - 2013
The adipocyte-derived hormone, leptin, is a master regulator of energy homeostasis. Leptin action in the central nervous system also contributes to arterial pressure regulation through its capacity to increase renal sympathetic outflow. The accumulating evidence pointing to a key role for leptin in the adverse sympathetic and cardiovascular consequences of ...
Marchi-Alves Leila Maria - - 2012
The objectives of this study were to identify and compare the prevalence of metabolic syndrome among hypertensive individuals and people with normal blood pressure measurements. The metabolic syndrome definition used in this study is that of the National Cholesterol Education Program/Adult Treatment Panel (NCEP-ATP III). The data referring to the ...
Diedrich André A Departments of Medicine and Physiology, Hunter Holmes McGuire Department of Veterans Affairs Medical Center, Medical College of Virginia at Virginia Commonwealth University, Richmond, Virginia, - - 2013
Because it is likely that, in healthy human subjects, baroreflex mechanisms operate continuously, independent of experimental interventions, we asked the question, In what ways might study of unprovoked, very infrequent muscle sympathetic bursts inform baroreflex physiology? We closely examined arterial pressure and R-R interval responses of 11 supine healthy young ...
Weber Thomas - - 2012
Increased activity of the sympathetic nervous system plays a major role in the pathophysiology of primary arterial hypertension. Interventional renal sympathetic denervation (RSD) is a novel percutaneous treatment, decreasing sympathetic activity and consecutively blood pressure by ablating sympathetic nervous fibers located in the adventitia of the renal arteries. The procedure ...
Kim Dong Hee DH Hand Research Laboratory, Departments of Biomedical Engineering and Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, - - 2013
We investigated morphological changes of a released carpal tunnel in response to variations of carpal tunnel pressure. Pressure within the carpal tunnel is known to be elevated in patients with carpal tunnel syndrome and dependent on wrist posture. Previously, increased carpal tunnel pressure was shown to affect the morphology of ...
Hering Dagmara - - 2012
Renal denervation (RDN) has been shown to reduce blood pressure (BP) and muscle sympathetic nerve activity (MSNA) in patients with resistant hypertension. The mechanisms underlying sympathetic neural inhibition are unknown. We examined whether RDN differentially influences the sympathetic discharge pattern of vasoconstrictor neurons in patients with resistant hypertension. Standardized office ...
Hofstetter Simmon - - 2013
The effects of high pressure, temperature, and antimicrobial compounds on endospores of Clostridium spp. were examined. Minimal inhibitory concentrations (MIC) of nisin and reutericyclin were determined for vegetative cells and endospores of Clostridium sporogenes ATCC 7955, Clostridium beijerinckii ATCC 8260, and Clostridium difficile 3195. Endospores of C. sporogenes ATCC 7955 and ...
Mizuno Masaki M Departments of Health Care Sciences, University of Texas Southwestern Medical Center, Dallas, TX, - - 2013
Small-for-gestational-age infants are known to develop hypertension in adulthood. This prenatal programming of hypertension (PPH) can result from several insults including maternal dietary protein deprivation, uteroplacental insufficiency, and prenatal administration of glucocorticoids. The mechanisms underlying the development of hypertension remain unclear although the sympathetic nervous system has been indirectly implicated. ...
Chen Siyuan - - 2012
Objective: The objective of this work was to prepare coenzyme Q10 loaded nanostructured lipid carriers (Q10-NLC) and evaluate its epidermal targeting effect. Methods: Q10-NLC was prepared by high-pressure microfluidics technique. Formulations and preparation parameters were optimized with response surface design. Q10-NLC was characterized by PCS, TEM, DSC and PXRD. The ...
Dietrich P - - 2012
BACKGROUND & AIMS: Splanchnic vasodilation is an essential disturbance in portal hypertension. Increased systemic sympathetic-nerve-activity is well-known, but potential corresponding vascular desensitization is characterized incompletely. Release of splanchnic sympathetic neurotransmitters noradrenaline [NA] and co-transmitter neuropeptide Y [NPY] remains to be elucidated. Finally, the effects of exogenous NPY on these mechanisms ...
Wang Yuexiang - - 2012
Although a close relationship between carpal tunnel pressure and median nerve dysfunction has been found, the current methods for pressure measurements are invasive, using a catheter in the carpal canal to monitor the pressure. A noninvasive method for quantifying carpal tunnel pressure would be useful as an alternative to the ...
Ng W-F WF Institute of Cellular Medicine, Newcastle University, NE2 4HH, - - 2012
Symptoms in keeping with autonomic dysfunction are commonly described by primary Sjögrens syndrome patients (pSS); whether objective abnormalities of autonomic function occur is unclear. This study set out to explore dynamic cardiovascular autonomic responses in pSS and their relationship with symptoms and quality of life. Twenty-one people from the UK ...
Bravo F I - - 2012
This paper describes a study on the influence of the high-pressure-release rate on the protein distribution between the soluble and colloidal fractions of milk. Skim milk, without or with sulfhydryl-blocking agents, was pressure treated at 250 and 350 MPa for 5 to 15 min at 25°C, applying different pressure-release rates ...
Prince Ethan A - - 2012
Transluminal ablation of renal artery sympathetic nerves has been shown to provide a significant and durable reduction in blood pressure with very low complication rates. Additional publications have documented improvement in insulin sensitivity, obstructive sleep apnea indices, and frequency and severity of congestive heart failure in subgroups undergoing the procedure. ...
Ramuz Marc - - 2012
Optical pressure sensors are highly responsive and are unaffected by surrounding parameters such as electronic noise, humidity, temperature etc. A new type of optical pressure sensor is described that demonstrates the stretchability and transparency of a polydimethylsiloxane waveguide, while also serving as a substrate. The pressure sensors are both robust ...
Allen Joshua W - - 2012
Sources of error in determining pressure-dependent rate coefficients are discussed in the context of automatic mechanism generation. Often the approximations made in converting the master equations into phenomenological rate coefficients are not the largest source of error. However, in some cases some of the methods are seriously inaccurate. Automation of ...
Henderson Lee W - - 2012
The unchanging rate of symptomatic hypotension that attends maintenance hemodialysis and its link to sodium/volume overload are explored. Correlations between interdialytic weight gain, ultrafiltration rate, hypertension, and mortality are found to be strong. Suggestions/opinions for correcting this unfortunate clinical reality are offered.
Tsuda Kazushi - - 2012
Many Studies suggest that changes in sympathetic nerve activity in the central nervous system might have a crucial role in blood pressure control. The present paper discusses evidence in support of the concept that the brain renin-angiotensin system (RAS) might be linked to sympathetic nerve activity in hypertension. The amount ...
Khalil Mona F - - 2011
Egypt includes many desert and rural areas. The small uptown fertile areas are placed under illegal enormous pressure of existing resources, where intensive agricultural practices are performed in combination with high population densities. The brown necked ravens (Corvus ruficollis) are attracted in huge numbers to such areas. The birds are ...
Vella Dominic - - 2012
Pressurized elastic capsules arise at scales ranging from the 10 m diameter pressure vessels used to store propane at oil refineries to the microscopic polymeric capsules that may be used in drug delivery. Nature also makes extensive use of pressurized elastic capsules: plant cells, bacteria and fungi have stiff walls, ...
Hann C E - - 2011
The cardiac muscle activation or driver function, is a major determinant of cardiovascular dynamics, and is often approximated by the ratio of the left ventricle pressure to the left ventricle volume. In an intensive care unit, the left ventricle pressure is usually never measured, and the left ventricle volume is ...
Anju Negi - - 2011
Seeds of 3 newly released moth bean (Phaselous aconitifolius Jacq.) varieties ('Jwala', 'RMO 225' and 'RMO 257') and 1 local variety of moth bean were pressure cooked and microwave oven cooked to find out the comparative effect of heating on total soluble solids (TSS), reducing sugars, non-reducing sugars and starch ...
Bjällmark Anna - - 2011
Cardiovascular disease is the leading cause of death in patients with end-stage renal disease (ESRD). The aim of this study was to investigate the changes in cardiovascular function induced by a single session of hemodialysis (HD) by the analysis of cardiovascular dynamics using wave intensity wall analysis (WIWA) and of ...
Singh Gautam K - - 2010
The heart is a complex and sophisticated pump that cycles between two phases: diastole, during which a compliant chamber (ventricle) allows the blood to fill from a reservoir chamber (atrium) of low pressure, and systole, during which a stiff chamber with rapidly rising pressure ejects the blood into an arterial ...
Warnick Stephen J SJ - - 2010
Our patient had the classic square root sign typical of constrictive pericarditis, but contrary to what we would have expected, his end-diastolic pressures did not equalize.
Yoshikawa Yoshiro - - 2010
We have previously shown that a newly developed calpain inhibitor, SNJ-1945 (SNJ), with good aqueous solubility prevents the heart from KCl arrest-reperfusion injury associated with the impairment of total Ca(2+) handling by inhibiting the proteolysis of alpha-fodrin as a cardioplegia. The aim of the present study was to investigate certain ...
Cohen Rose S - - 2010
A prospective, open-label, 3-month study was conducted to evaluate the feasibility and short-term clinical effect of subcutaneous erythropoietin injections in patients with anemia and heart failure with preserved ejection fraction (ejection fraction, 55%+/-2%). Using a dose-adjusted algorithm to effect a rate of rise in hemoglobin not to exceed 0.4 g/dL ...
Nahouraii Richard A - - 2010
This article focuses on static methods for determining preload, specifically pressure and volumetric indices measured at the bedside. The underlying ventricular function will determine where the patient is located on Frank-Starling ventricular function curve and the patient's response to a fluid challenge. The proper interpretation and use of such measures, ...
Takano Hiroshi - - 2010
OBJECTIVE: To assess differences in left ventricular contractile indices among dogs of 3 body sizes via 2-D speckle-tracking echocardiography (STE) and to determine body weight-independent systolic variables. ANIMALS: 37 clinically normal adult dogs. PROCEDURES: Dogs were allocated into 3 groups on the basis of body weight: small (<7kg), medium (7 ...
Kovács A - - 2010
The purpose of this study was to assess shortterm effects of transjugular intrahepatic shunt (TIPS) on cardiac function with cardiac magnetic resonance imaging (MRI) in patients with liver cirrhosis. Eleven patients (six males and five females) with intractable esophageal varices or refractory ascites were imaged with MRI at 1.5 T ...
Chaturvedi Rajiv R RR Division of Cardiology, Hospital for Sick Children, 555 University Ave, Toronto M5G 1X8, Canada. - - 2010
In ventricular dilatation or hypertrophy, an elevated end-diastolic pressure is often assumed to be secondary to increased myocardial stiffness, but stiffness is rarely measured in vivo because of difficulty. We measured in vitro passive stiffness of volume- or pressure-overloaded myocardium mainly from congenital heart disease. Endocardial ventricular biopsies were obtained ...
Lewinter Martin M - - 2010
The sarcomeric protein titin is a molecular spring responsible for passive tension and restoring forces of cardiomyocytes. Extension of titin as a function of sarcomere length (SL) has been studied in rodents, which predominantly express the smaller, stiffer N2B titin isoform. Large mammals coexpress roughly equal proportions of N2B and ...
Malbrain M L N G - - 2010
BACKGROUND: Volumetric monitoring with right ventricular end-diastolic volume indexed (RVEDVi) and global end-diastolic volume indexed (GEDVi) is increasingly being suggested as a superior preload indicator compared with the filling pressures central venous pressure (CVP) or the pulmonary capillary wedge pressure (PCWP). However, static monitoring of these volumetric parameters has not ...
Jhun Choon-Sik - - 2010
Passive constraint is used to prevent left ventricular dilation and subsequent remodeling. However, there has been concern about the effect of passive constraint on diastolic left ventricular chamber stiffness and pump function. This study determined the relationship between constraint, diastolic wall stress, chamber stiffness, and pump function. We tested the ...
Rozza Francesco - - 2009
Aim: To assess whether the association of a dietary supplement with a correct diet can decrease the incidence of metabolic syndrome. In particular, we studied the effect of a combination of Ortosiphon staminensis, which in rats exerts a diuretic effect, with policosanol, red yeast rice extract, berberine, folic acid and ...
Wachter Rolf - - 2009
We tested the hypothesis that, in heart failure with normal ejection fraction (HFNEF), diastolic dysfunction is accentuated at increasing heart rates, and this contributes to impaired frequency-dependent augmentation of cardiac output. In 17 patients with HFNEF (median age 69 years, 13 female) and seven age-matched control patients, systolic and diastolic ...
Schmitt Boris - - 2009
OBJECTIVES: This study sought to develop and validate a method for the integrated analysis of systolic and diastolic ventricular function. BACKGROUND: An integrated approach to assess ventricular pump function, myocontractility (end-systolic pressure-volume relationship [ESPVR]), and diastolic compliance (end-diastolic pressure-volume relation [EDPVR]) is of high clinical value. Cardiac magnetic resonance (CMR) ...
Ten Brinke Ellen A - - 2010
AIMS: To test a method to predict the end-diastolic pressure-volume relationship (EDPVR) from a single beat in patients with heart failure. METHODS AND RESULTS: Patients (New York Heart Association class III-IV) scheduled for mitral annuloplasty (n=9) or ventricular restoration (n=10) and patients with normal left ventricular function undergoing coronary artery ...
ten Brinke E A - - 2010
AIM: The end-systolic pressure-volume relationship (ESPVR) constructed from multiple pressure-volume (PV) loops acquired during load intervention is an established method to asses left ventricular (LV) contractility. We tested the accuracy of simplified single-beat (SB) ESPVR estimation in patients with severe heart failure. METHODS: Nineteen heart failure patients (NYHA III-IV) scheduled ...
Scheuren Karoline - - 2009
BACKGROUND AND OBJECTIVE: Central venous pressure, intrathoracic blood volume, and left ventricular end-diastolic area are reliable measures of cardiac preload under stable clinical conditions. The purpose of this study was to compare different preload parameters over 24 h under conditions of multiple, frequently changing treatments in early septic shock. METHODS: ...
Della Rocca Giorgio - - 2009
PURPOSE OF REVIEW: To highlight the recent developments in hemodynamic monitoring during liver and lung transplantation. RECENT FINDINGS: Even though a consensus on intraoperative hemodynamic monitoring is still lacking, the most frequently monitoring tool used is the pulmonary artery catheter (PAC). The filling pressures are widely accepted as not being ...
Goshka S L - - 2009
The duration of repolarization of subendocardial, intramural, and epicardial layers of dog ventricles was studied under conditions of volume overload of the heart in situ. Increased preload was modeled by rapid intravenous infusion of saline and rheopolygluquine. The activation-recovery interval was measured by flexible intramural electrodes inserted into the right ...
Yerebakan Can - - 2009
Pressure-volume loop measurements by cardiac catheterization constitute a highly reliable method for the direct beat-to-beat functional analysis of the heart. We aimed to prove its feasibility for the instantaneous evaluation of right ventricular performance in a novel experimental model of pulmonary regurgitation (PR). Four-month-old sheep (n=18, weighing 35-45 kg) were ...
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