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Mathew Paul G PG Brigham and Women's Hospital, Department of Neurology, John R. Graham Headache Center, Boston, MA, USA, - - 2014
Low intracranial pressure headaches can, at times, be refractory to treatment including multiple blood patches and preventative medications. Imaging studies are often unable to demonstrate a cerebrospinal fluid leak that is causing headache and other associated symptoms. Onabotulinum toxin A (BTX) injection is a treatment that has proven efficacy for ...
Wightman JoLynne D JD Central Michigan University, 106A Wightman Hall, Mt. Pleasant, MI, - - 2014
Cardiovascular disease is a leading cause of death globally. Many cardiovascular risk factors can be modified through lifestyle modification, including dietary patterns that emphasize daily consumption of a variety of fruits and vegetables. Recent observational and clinical studies suggest that flavonoids, especially those abundant in grapes and other berries, may ...
Bonilla Alvaro G AG Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, - - 2014
To determine ex vivo contact data on the equine medial tibial plateau loaded by an intact medial femoral condyle (MFC), by an MFC with an osteochondral defect, and with a screw inserted in lag fashion through the MFC defect. Ex vivo experiment. Stifles (n = 6). Horses (n = 4). Stifle joints were axially ...
Brothers R Matthew RM University of Texas at - - 2014
Volume loading normalizes tolerance to a simulated hemorrhagic challenge during heat stress, relative to thermoneutral conditions; however, the mechanism(s) are unknown. This project tested two unique hypotheses; the elevation of central blood volume via volume loading while heat stressed would: 1) increase left ventricular diastolic function, and 2) preserve left ...
Radstaak Mirjam M From the Behavioural Science Institute (M.R., S.A.E.G., M.A.J.K.), Radboud University Nijmegen, Nijmegen, the Netherlands; and Institute of Psychology (J.F.B.), Leiden University, Leiden, the - - 2014
This experimental study examined whether listening to self-chosen music after stress exposure improves mood, decreases subjective arousal and rumination, and facilitates cardiovascular recovery. Participants (N = 123) were exposed to a mental arithmetic task with harassment to induce stress. Afterward, participants were randomly assigned to one of four "recovery" conditions ...
Field Tiffany T Touch Research Institute, University of Miami Medical School, USA; Fielding Graduate University, USA. Electronic address: - - 2014
Moderate pressure massage has contributed to many positive effects including increased weight gain in preterm infants, reduced pain in different syndromes including fibromyalgia and rheumatoid arthritis, enhanced attentiveness, reduced depression and enhanced immune function (increased natural killer cells and natural killer cell activity).Surprisingly, these recent studies have not been reviewed, ...
Rolfes Melissa A MA Department of Medicine, Medical School, University of Minnesota, Minneapolis, MN, - - 2014
 Cryptococcal meningitis is the most common cause of adult meningitis in sub-Saharan Africa. Raised intracranial pressure (ICP) is common in cryptococcosis. Prior studies suggest elevated ICP is associated with mortality, and guidelines recommend frequent lumbar punctures (LPs) to control ICP. However, the magnitude of the impact of LPs on cryptococcal-related ...
Phillips Rob R The School of Medicine, The University of Queensland, Brisbane, Australia, - - 2014
Fluid infusion is one of the most common critical care interventions, yet approximately 50 % of all fluid interventions are unnecessary and potentially harmful. An improved approach to identification of fluid responsiveness is of clinical importance. Currently fluid responsiveness is most frequently identified by blood pressure (BP) measurements or a surrogate. ...
Seibel C C Experimental Thermodynamics, Ruhr-University Bochum, Universitätsstr. 150, D-44801 Bochum, - - 2014
Inline process control by measurement of velocity of sound of fluids is a direct and comprehensive technique [J. D. N. Cheeke and Z. Wang, "Acoustic wave gas sensors," Sens. Actuators B 59, 146-153 (1999); J. W. Grate, S. J. Martin, and R. M. White, "Acoustic wave microsensors," Anal. Chem. 65, ...
Krishnakumar Deepa D Department of Paediatric Neurology, Addenbrooke's Hospital, Cambridge, - - 2014
Idiopathic intracranial hypertension (IIH) is prone to misdiagnosis. Our aim was to identify the reasons for this in children in our region referred for suspected IIH. We reviewed the records of all children referred with symptoms and/or signs consistent with raised intracranial pressure (ICP) and normal magnetic resonance imaging of ...
Park Jai Y JY Department of Anesthesiology and Pain Medicine, The Armed Forces Capital Hospital, Seoul, Rep. of - - 2014
Objective: Differences in the cardiovascular and hypothalamic-pituitary-adrenal (HPA) axis functions at high altitudes (HAs) between visitors to and natives of HA were examined. Methods: The cardiovascular functions and peripheral oxygen saturation (SPO2) were monitored, and the cortisol awakening response (CAR) and nighttime cortisol concentration (NCC), as indices of the HPA ...
Portaluppi Francesco - - 2014
In normal conditions, the temporal organization of blood pressure (BP) is mainly controlled by neuroendocrine mechanisms. Above all, the monoaminergic systems (including variations in activity of the autonomous nervous system, and in secretion of biogenic amines) appear to integrate the major driving factors of temporal variability, but evidence is available ...
Drummond John C JC VA Medical Center, Anesthesia Service - 125, University of California, 3350 La Jolla Village Drive, San Diego, CA, 92161, USA, - - 2014
When positioning patients with meningocele and meningomyelocele, it is standard practice to avoid direct pressure on the lesions. That caution is intended to prevent injury to neural elements within the lesion and violation of the cerebrospinal fluid space. We herein report an additional hazard of direct intraoperative pressure on such ...
Johansson Staffan B SB Micro and Nanosystems, KTH Royal Institute of Technology, Osquldas Väg 10, 10044, Stockholm, Sweden, - - 2014
This paper reports a novel micro electro mechanical system (MEMS) valve with posture controlled flow characteristics for improved treatment of hydrocephalus, a disease that is characterized by elevated pressure in the cerebrospinal fluid (CSF) that surrounds the brain and spinal cord. In contrast to conventional differential pressure CSF valves, the ...
Kawai Hisashi - - 2014
Objectives: Watertight dural closure is imperative after neurosurgical procedures because inadequately treated leakage of cerebrospinal fluid (CSF) can have serious consequences. In this study, the authors test the use of a new gelatin glue as a dural sealant in in vitro and in vivo canine models of transdural CSF leakage. ...
Wakerley Benjamin R BR Division of Neurology, National University Health System, - - 2014
Transcranial Doppler (TCD) ultrasonography is a noninvasive bedside tool that can evaluate cerebral blood flow hemodynamics in major intracranial arteries. TCD-derived pulsatility index (PI) is believed to be influenced by intracranial pressure (ICP). To correlate TCD-PI with cerebrospinal fluid (CSF) pressure (representing ICP), measured by standard lumbar puncture (LP) manometry. ...
Capel Cyrille - - 2014
Objectives: We studied possible link between cerebrospinal fluid (CSF) compensation and indices describing pulsatile inflow of cerebral arterial blood. Methods: A total of 50 infusion tests performed in patients with symptoms of normal pressure hydrocephalus (NPH) were examined retrospectively. Waveforms of CSF pressure, noninvasive arterial blood pressure (ABP), and transcranial ...
Archambault-Léger Véronique V Dartmouth College, Hanover, NH 03755, United States; DOE BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831, United States. Electronic address: - - 2014
The present study investigates fluid mechanical properties of cellulosic feedstocks relevant to flow through (FT) pretreatment for biological conversion of cellulosic biomass. The results inform identifying conditions for which FT pretreatment can be implemented in a practical context. Measurements of pressure drop across packed beds, viscous compaction and water absorption ...
Tapolyai Mihály B MB Fresenius Medical Care, Semmelweis University, Budapest, Hungary; Department of Medicine, Division of Nephrology, WJB Dorn VA Medical Center, Columbia, South Carolina, - - 2014
Ultrafiltration (UF) is a common procedure performed during almost all dialysis sessions. During UF, several liters of fluid are removed; however, what proportion of this fluid is removed from which fluid space could not be clinically measured easily until now; we designed this study to evaluate the fluid spaces most ...
Sano Yuji Y Atmosphere and Ocean Research Institute, University of Tokyo, Kashiwa-noha, Chiba 277-8564, - - 2014
Geophysical evidence suggests that fluids along fault planes have an important role in generating earthquakes; however, the nature of these fluids has not been well defined. The 2011 magnitude 9.0 Tohoku-Oki earthquake ruptured the interface between the subducting Pacific plate and the overlying Okhotsk plate. Here we report a sharp ...
Graff-Radford Steven B SB Cedars-Sinai Medical Center, Los Angeles, CA, - - 2014
Headache resulting from idiopathic intracranial hypertension (IIH) in a population of moderately to obese women of childbearing age. The causes overall remain unclear. With this review, we provide an overview of clinical treatment and management strategies. IIH management is dependent on the signs and symptoms presented. Symptomatic treatment should attempt ...
Illing Elisa E Department of Surgery, Division of Otolaryngology, Medical University of South Carolina, Charleston, - - 2014
Spontaneous cerebrospinal fluid (CSF) leaks/encephaloceles are proven to be associated with intracranial hypertension by objective measurements of CSF pressure during or following endoscopic repair. A common area of involvement is a pneumatized lateral recess of the sphenoid (LRS) sinus, where prolonged intracranial pressures lead to arachnoid pits and subsequent development ...
Sharifi Guive G Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
Acquired non-traumatic transethmoidal encephaloceles are very infrequent lesions that are generally caused by a tumor or hydrocephalus. As far as we know, there is no reported case of encephalocele after CSF diversion in the literature. We present a 25-year-old woman with hydrocephalus due to aquiductal stenosis who was treated with ...
Klarica Marijan M Department of Pharmacology and Croatian Institute for Brain Research, School of Medicine University of Zagreb, Zagreb, - - 2014
Intracranial hypertension is a severe therapeutic problem, as there is insufficient knowledge about the physiology of cerebrospinal fluid (CSF) pressure. In this paper a new CSF pressure regulation hypothesis is proposed. According to this hypothesis, the CSF pressure depends on the laws of fluid mechanics and on the anatomical characteristics ...
Desmond Mary E ME Department of Biology, Villanova University, Villanova, PA, - - 2014
Expansion of the hollow fluid-filled embryonic brain occurs by an increase in intraluminal pressure created by accumulation of cerebrospinal fluid (CSF). Experiments have shown a direct correlation between cavity pressure and cell proliferation within the neuroepithelium. These findings lead us to ask how mechanistically this might come about. Are there ...
Mulargia Francesco F Università degli Studi di Bologna, Dipartimento di Fisica e Astronomia, Viale Carlo Berti Pichat, 6/2- 40127 Bologna - - - 2014
The physical mechanism of the anthropogenic triggering of large earthquakes on active faults is studied on the basis of experimental phenomenology, i.e., that earthquakes occur on active tectonic faults, that crustal stress values are those measured in situ and, on active faults, comply to the values of the stress drop ...
Beschorner Kurt E - - 2013
Previous research on slip and fall accidents has suggested that pressurized fluid between the shoe and floor is responsible for initiating slips yet this effect has not been verified experimentally. This study aimed to (1) measure hydrodynamic pressures during slipping for treaded and untreaded conditions; (2) determine the effects of ...
Dicpinigaitis Peter V - - 2013
Loss of consciousness following cough was first described in 1876 as "laryngeal vertigo" Since then, several hundred cases of what is now most commonly termed cough syncope have been reported, often in association with various medical conditions. Some early authors assumed this entity to be a form of epilepsy, but ...
van der Pas Rob - - 2013
Objective/MethodsCushing's disease (CD) is often accompanied by hypertension. CD can be treated surgically and, given the expression of somatostatin subtype 5 and dopamine 2 receptors by corticotroph pituitary adenomas, pharmacologically. Indeed, we recently observed that stepwise medical combination therapy with the somatostatin-analog pasireotide, the dopamine-agonist cabergoline and ketoconazole (which directly ...
Daouk Joël - - 2013
Normal-pressure hydrocephalus (NPH) and Alzheimer's disease (AD) have some similar clinical features and both involve white matter and cerebrospinal fluid (CSF) disorders. To compare putative relationships between ventricular morphology, CSF flow, and white matter diffusion in AD and NPH. Thirty patients (18 with AD and 12 with suspected NPH) were ...
Hassan Kaukab M KM Department of Internal Medicine, Division of Neurology, Command Hospital, West Bengal University of Health Sciences, Alipore, Kolkata, West Bengal, India ; Division of Neurology, Command Hospital, West Bengal University of Health Sciences, Alipore, Kolkata, West Bengal, - - 2013
The diagnosis of spontaneous intracranial hypotension or cerebrospinal fluid (CSF) hypovolemia syndrome requires a high index of suspicion and meticulous history taking, demonstration of low CSF pressure and/or neuroimaging features. A 31-year-old male, presented with subacute onset moderate occipital and sub-occipital headaches precipitated by upright posture and relieved on recumbency ...
Alkins Ryan R Physical Sciences Platform, Sunnybrook Research Institute, Toronto; - - 2013
Transcranial focused ultrasound is increasingly being investigated as a minimally invasive treatment for a range of intracranial pathologies. At higher peak rarefaction pressures than those used for thermal ablation, focused ultrasound can initiate inertial cavitation and create holes in the brain by fractionation of the tissue elements. The authors investigated ...
Stocker Sean D - - 2013
Excess dietary salt intake is a major contributing factor to the pathogenesis of salt-sensitive hypertension. Strong evidence suggests that salt-sensitive hypertension is attributed to renal dysfunction, vascular abnormalities, and activation of the sympathetic nervous system. Indeed, sympathetic nerve transections or interruption of neurotransmission in various brain centers lowers arterial blood ...
Geeraerts Thomas - - 2013
Optic nerve sheath diameter enlargement measured by ultrasound is known to be associated with raised intracranial pressure (ICP). Magnetic resonance imaging (MRI) of the cerebrospinal fluid (CSF) surrounding the optic nerve has been found, in an elegant study published in Critical Care, to correlate well with lumbar CSF opening pressure, ...
Zhang Zheng - - 2013
To assess whether a Valsalva manoeuver influences intra-ocular pressure (IOP), cerebrospinal fluid pressure (CSF-P) and, by a change in the trans-laminar cribrosa pressure difference, optic nerve head morphology. In the first part of the study, 20 neurological patients (study group 'A') underwent measurement of IOP and lumbar CSF-P measurement in ...
Kotake Yoshifumi - - 2013
This prospective observational study compared the volume effect between hydroxyethyl starch (HES) and crystalloid solution and its context dependency in intraoperative goal-directed fluid management. With institutional review board (IRB) approval, 35 patients undergoing major gastrointestinal surgery were enrolled. Fluid challenge consisting of 250 ml of either bicarbonate Ringer solution (BRS) or ...
- - 2013
A short-cut review was carried out to determine whether cerebrospinal fluid (CSF) opening pressure is significantly affected by the patient's leg position during the procedure. A total of 1410 papers was found using the reported search, of which five were considered relevant to the three-part question. The author, date and ...
Bono Francesco - - 2013
Riggeal et al.(1) found no correlation between the degree of transverse sinus stenosis (TSS) and the clinical course in idiopathic intracranial hypertension (IIH). There is no direct evidence of normalization of the CSF pressure in this series and this demonstration is needed to support their observation. The authors did not ...
Guo Yinghua - - 2013
Pulmonary arterial hypertension (PAH) is characterized by a progressive increase in pulmonary arterial pressure and vascular resistance. Despite advances in therapy for PAH, its treatment and prognosis remain poor. We aimed to investigate whether the transplantation of bone marrow mesenchymal stem cells (MSCs) overexpressing hepatocyte growth factor (HGF), alone or ...
Matsumae Mitsunori - - 2013
Object New approaches for understanding CSF motion in healthy individuals and patients with hydrocephalus and Chiari malformation are presented. The velocity and the pressure gradient of CSF motion were determined using phase contrast (PC) MRI. Methods The authors examined 11 healthy control subjects and 2 patients (1 with hydrocephalus and ...
Hardwick Lisa M - - 2013
A scientific rationale is proposed for establishment of acceptance criteria for leak rates in pharmaceutical freeze dryers. A method was developed to determine the quantity of air that could leak into any lyophilizer from the outside while still maintaining Class 100 / Grade A microbial conditions. A lyophilizing product is ...
Xie Xiaobin - - 2013
The orbital subarachnoid space surrounding the optic nerve is continuous with the circulation system for cerebrospinal fluid (CSF) and can be visualized using magnetic resonance imaging (MRI). We hypothesized that the orbital subarachnoid space width (OSASW) is correlated with and can serve as a surrogate for intracranial pressure (ICP). Our ...
Preuss M - - 2013
Hydrocephalus is still a not well-understood diagnostic and a therapeutic dilemma because of the lack of sufficient and comprehensive model of cerebrospinal fluid circulation and pathological alterations. Based on current studies, reviews, and knowledge of cerebrospinal fluid dynamics, brain water dynamics, intracranial pressure, and cerebral perfusion physiology, a new concept ...
Garcia Maria - - 2013
Hydrocephalus includes a range of disorders characterized by clinical symptoms, abnormal brain imaging and altered cerebrospinal fluid (CSF) dynamics. Infusion tests can be used to study CSF circulation in patients with hydrocephalus. In them, intracranial pressure (ICP) is deliberately raised and CSF circulation disorders evaluated through measurements of the resulting ...
Yatsushiro Satoshi - - 2013
This work was performed to indicate the usefulness of magnetic resonance (MR) 4-dimentional phase contrast (4D-PC) technique in assessing CerebroSpinal Fluid (CSF) motion in comparison with the time-Spatial Labeling Inversion Pulse (Time-SLIP) technique. 4D-velocity vector, their curl, and, pressure gradient were evaluated in both flow phantom, and normal volunteers and ...
Mokri Bahram - - 2013
Spontaneous intracranial hypotension typically results from spontaneous cerebrospinal fluid (CSF) leak, often at spine level and only rarely from skull base. Once considered rare, it is now diagnosed far more commonly than before and is recognized as an important cause of headaches. CSF leak leads to loss of CSF volume. ...
Klarica M - - 2013
Acute osmolar loading of cerebrospinal fluid within one lateral ventricle of dogs was examined as a cause of water extraction from the bloodstream and an increase in intracranial pressure. We have shown that a certain amount of (3)H2O from the bloodstream enters osmotically loaded cerebrospinal fluid significantly faster, hence causing ...
Clarke Elizabeth C - - 2013
The pathogenesis of syringomyelia in association with Chiari malformation (CM) is unclear. Studies of patients with CM have shown alterations in the CSF velocity profile and these could contribute to syrinx development or enlargement. Few studies have considered the fluid mechanics of CM patients with and without syringomyelia separately. Three ...
Chaaban Mohamad R - - 2013
BACKGROUND: Acetazolamide has become a standard treatment for cerebrospinal fluid (CSF) leaks associated with intracranial hypertension. The purpose of the current study was to evaluate the effectiveness of acetazolamide at decreasing elevated CSF pressure in this patient population. METHODS: Prospective evaluation and data collection of high intracranial pressure CSF leaks ...
Berdahl John P - - 2013
Low cerebrospinal fluid (CSF) pressure has recently been implicated in the pathogenesis of glaucoma. Although little data currently exists, various systemic parameters may affect CSF pressure. CSF pressure increases with increased body mass index (BMI), which corroborates recent studies that have demonstrated elevated BMI may be protective of glaucoma. CSF ...
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