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Okada Yoko Y From the Department of Geriatrics and Neurology, Ehime University Graduate School of Medicine, Toon-City, Ehime, Japan (Y.O., K.K., M.O., T.N., M.I., T.M.); and Department of Medical Genetics, Kyoto University Graduate School of Medicine, Kyoto, Japan - - 2014
Arterial stiffness, a risk factor of brain small vessel diseases (SVD), causes hemodynamic changes. Mechanical stresses, circumferential wall tension (WT), and shear stress (SS) may change with arterial stiffness and be related to SVD. We investigated the associations between mechanical stresses and arterial stiffness and SVD. A total of 1296 ...
Shaked Sivan S Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, 69978, Tel Aviv, - - 2014
Adenomyosis is a disease in which ectopic endometrial glands and stromal cells appear in the uterine myometrium. This pathology is common among women of reproductive age, and in addition to chronic pelvic pain and heavy periods it may also cause infertility. The 'tissue injury and repair' mechanism in response to ...
Queisser Nina N Institute of Pharmacology and Toxicology, University of Würzburg, Würzburg, - - 2014
Mineralocorticoid receptor blockers show antifibrotic potential in hepatic fibrosis. The mechanism of this protective effect is not known yet, although reactive oxygen species seem to play an important role. Here, we investigated the effects of elevated levels of aldosterone (Ald), the primary ligand of the mineralocorticoid receptor, on livers of ...
Tomiyama Hirofumi H Second Department of Internal Medicine, Tokyo Medical University, Japan; - - 2014
We determined whether any significant association exists between change in late systolic cardiac load with time, estimated by radial pressure waveform analysis, and development of cardiac hemodynamic stress in individuals with preserved cardiac function. Brachial-ankle pulse wave velocity, radial augmentation index (rAI), first peak of the radial pressure waveform (SP1), ...
Mathew Paul G PG Brigham and Women's Hospital, Department of Neurology, John R. Graham Headache Center, Boston, MA, USA, - - 2014
Low intracranial pressure headaches can, at times, be refractory to treatment including multiple blood patches and preventative medications. Imaging studies are often unable to demonstrate a cerebrospinal fluid leak that is causing headache and other associated symptoms. Onabotulinum toxin A (BTX) injection is a treatment that has proven efficacy for ...
Chang Ching-Min CM Institute of Environmental Engineering, National Chiao Tung University, Hsinchu, - - 2014
Fluid-filled granular soils experience changes in total stress because of earth and oceanic tides, earthquakes, erosion, sedimentation, and changes in atmospheric pressure. The pore volume may deform in response to the changes in stress and this may lead to changes in pore fluid pressure. The transient fluid flow can therefore ...
Cheng Jason J *Khoo Teck Puat Hospital, Singapore, Singapore †Mechanical and Industrial Engineering Department §Department of Ophthalmology, University of Toronto5and Department of Ophthalmology, Toronto Western Hospital, Toronto, ON, Canada ‡Institut Català de la Retina, Barcelona, - - 2014
To determine the pressure required to prime an Ahmed Glaucoma Valve (AGV) and determine whether the valve can be damaged by "over-priming pressure." Three AGVs, a syringe pump, and a manometer were used to assess priming pressure. Balanced salt solution was pumped through the AGV tube at increasing pressures until ...
Wightman JoLynne D JD Central Michigan University, 106A Wightman Hall, Mt. Pleasant, MI, - - 2014
Cardiovascular disease is a leading cause of death globally. Many cardiovascular risk factors can be modified through lifestyle modification, including dietary patterns that emphasize daily consumption of a variety of fruits and vegetables. Recent observational and clinical studies suggest that flavonoids, especially those abundant in grapes and other berries, may ...
Bonilla Alvaro G AG Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, - - 2014
To determine ex vivo contact data on the equine medial tibial plateau loaded by an intact medial femoral condyle (MFC), by an MFC with an osteochondral defect, and with a screw inserted in lag fashion through the MFC defect. Ex vivo experiment. Stifles (n = 6). Horses (n = 4). Stifle joints were axially ...
Brothers R Matthew RM University of Texas at - - 2014
Volume loading normalizes tolerance to a simulated hemorrhagic challenge during heat stress, relative to thermoneutral conditions; however, the mechanism(s) are unknown. This project tested two unique hypotheses; the elevation of central blood volume via volume loading while heat stressed would: 1) increase left ventricular diastolic function, and 2) preserve left ...
Radstaak Mirjam M From the Behavioural Science Institute (M.R., S.A.E.G., M.A.J.K.), Radboud University Nijmegen, Nijmegen, the Netherlands; and Institute of Psychology (J.F.B.), Leiden University, Leiden, the - - 2014
This experimental study examined whether listening to self-chosen music after stress exposure improves mood, decreases subjective arousal and rumination, and facilitates cardiovascular recovery. Participants (N = 123) were exposed to a mental arithmetic task with harassment to induce stress. Afterward, participants were randomly assigned to one of four "recovery" conditions ...
Sardarian Ahmadreza - - 2014
The ideal built-in tip and torque values of the straight wire appliance reduce the need for wire bending and hence reduce chair time. The vertical position of the bracket on the tooth surface can alter the torque exerted on the tooth. This is a result of the altered surface curvature ...
Field Tiffany T Touch Research Institute, University of Miami Medical School, USA; Fielding Graduate University, USA. Electronic address: - - 2014
Moderate pressure massage has contributed to many positive effects including increased weight gain in preterm infants, reduced pain in different syndromes including fibromyalgia and rheumatoid arthritis, enhanced attentiveness, reduced depression and enhanced immune function (increased natural killer cells and natural killer cell activity).Surprisingly, these recent studies have not been reviewed, ...
Rolfes Melissa A MA Department of Medicine, Medical School, University of Minnesota, Minneapolis, MN, - - 2014
 Cryptococcal meningitis is the most common cause of adult meningitis in sub-Saharan Africa. Raised intracranial pressure (ICP) is common in cryptococcosis. Prior studies suggest elevated ICP is associated with mortality, and guidelines recommend frequent lumbar punctures (LPs) to control ICP. However, the magnitude of the impact of LPs on cryptococcal-related ...
Phillips Rob R The School of Medicine, The University of Queensland, Brisbane, Australia, - - 2014
Fluid infusion is one of the most common critical care interventions, yet approximately 50 % of all fluid interventions are unnecessary and potentially harmful. An improved approach to identification of fluid responsiveness is of clinical importance. Currently fluid responsiveness is most frequently identified by blood pressure (BP) measurements or a surrogate. ...
Seibel C C Experimental Thermodynamics, Ruhr-University Bochum, Universitätsstr. 150, D-44801 Bochum, - - 2014
Inline process control by measurement of velocity of sound of fluids is a direct and comprehensive technique [J. D. N. Cheeke and Z. Wang, "Acoustic wave gas sensors," Sens. Actuators B 59, 146-153 (1999); J. W. Grate, S. J. Martin, and R. M. White, "Acoustic wave microsensors," Anal. Chem. 65, ...
Krishnakumar Deepa D Department of Paediatric Neurology, Addenbrooke's Hospital, Cambridge, - - 2014
Idiopathic intracranial hypertension (IIH) is prone to misdiagnosis. Our aim was to identify the reasons for this in children in our region referred for suspected IIH. We reviewed the records of all children referred with symptoms and/or signs consistent with raised intracranial pressure (ICP) and normal magnetic resonance imaging of ...
Park Jai Y JY Department of Anesthesiology and Pain Medicine, The Armed Forces Capital Hospital, Seoul, Rep. of - - 2014
Objective: Differences in the cardiovascular and hypothalamic-pituitary-adrenal (HPA) axis functions at high altitudes (HAs) between visitors to and natives of HA were examined. Methods: The cardiovascular functions and peripheral oxygen saturation (SPO2) were monitored, and the cortisol awakening response (CAR) and nighttime cortisol concentration (NCC), as indices of the HPA ...
Portaluppi Francesco - - 2014
In normal conditions, the temporal organization of blood pressure (BP) is mainly controlled by neuroendocrine mechanisms. Above all, the monoaminergic systems (including variations in activity of the autonomous nervous system, and in secretion of biogenic amines) appear to integrate the major driving factors of temporal variability, but evidence is available ...
Drummond John C JC VA Medical Center, Anesthesia Service - 125, University of California, 3350 La Jolla Village Drive, San Diego, CA, 92161, USA, - - 2014
When positioning patients with meningocele and meningomyelocele, it is standard practice to avoid direct pressure on the lesions. That caution is intended to prevent injury to neural elements within the lesion and violation of the cerebrospinal fluid space. We herein report an additional hazard of direct intraoperative pressure on such ...
Johansson Staffan B SB Micro and Nanosystems, KTH Royal Institute of Technology, Osquldas Väg 10, 10044, Stockholm, Sweden, - - 2014
This paper reports a novel micro electro mechanical system (MEMS) valve with posture controlled flow characteristics for improved treatment of hydrocephalus, a disease that is characterized by elevated pressure in the cerebrospinal fluid (CSF) that surrounds the brain and spinal cord. In contrast to conventional differential pressure CSF valves, the ...
Kawai Hisashi - - 2014
Objectives: Watertight dural closure is imperative after neurosurgical procedures because inadequately treated leakage of cerebrospinal fluid (CSF) can have serious consequences. In this study, the authors test the use of a new gelatin glue as a dural sealant in in vitro and in vivo canine models of transdural CSF leakage. ...
Wakerley Benjamin R BR Division of Neurology, National University Health System, - - 2014
Transcranial Doppler (TCD) ultrasonography is a noninvasive bedside tool that can evaluate cerebral blood flow hemodynamics in major intracranial arteries. TCD-derived pulsatility index (PI) is believed to be influenced by intracranial pressure (ICP). To correlate TCD-PI with cerebrospinal fluid (CSF) pressure (representing ICP), measured by standard lumbar puncture (LP) manometry. ...
Capel Cyrille - - 2014
Objectives: We studied possible link between cerebrospinal fluid (CSF) compensation and indices describing pulsatile inflow of cerebral arterial blood. Methods: A total of 50 infusion tests performed in patients with symptoms of normal pressure hydrocephalus (NPH) were examined retrospectively. Waveforms of CSF pressure, noninvasive arterial blood pressure (ABP), and transcranial ...
Archambault-Léger Véronique V Dartmouth College, Hanover, NH 03755, United States; DOE BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831, United States. Electronic address: - - 2014
The present study investigates fluid mechanical properties of cellulosic feedstocks relevant to flow through (FT) pretreatment for biological conversion of cellulosic biomass. The results inform identifying conditions for which FT pretreatment can be implemented in a practical context. Measurements of pressure drop across packed beds, viscous compaction and water absorption ...
Tapolyai Mihály B MB Fresenius Medical Care, Semmelweis University, Budapest, Hungary; Department of Medicine, Division of Nephrology, WJB Dorn VA Medical Center, Columbia, South Carolina, - - 2014
Ultrafiltration (UF) is a common procedure performed during almost all dialysis sessions. During UF, several liters of fluid are removed; however, what proportion of this fluid is removed from which fluid space could not be clinically measured easily until now; we designed this study to evaluate the fluid spaces most ...
Sano Yuji Y Atmosphere and Ocean Research Institute, University of Tokyo, Kashiwa-noha, Chiba 277-8564, - - 2014
Geophysical evidence suggests that fluids along fault planes have an important role in generating earthquakes; however, the nature of these fluids has not been well defined. The 2011 magnitude 9.0 Tohoku-Oki earthquake ruptured the interface between the subducting Pacific plate and the overlying Okhotsk plate. Here we report a sharp ...
Graff-Radford Steven B SB Cedars-Sinai Medical Center, Los Angeles, CA, - - 2014
Headache resulting from idiopathic intracranial hypertension (IIH) in a population of moderately to obese women of childbearing age. The causes overall remain unclear. With this review, we provide an overview of clinical treatment and management strategies. IIH management is dependent on the signs and symptoms presented. Symptomatic treatment should attempt ...
Illing Elisa E Department of Surgery, Division of Otolaryngology, Medical University of South Carolina, Charleston, - - 2014
Spontaneous cerebrospinal fluid (CSF) leaks/encephaloceles are proven to be associated with intracranial hypertension by objective measurements of CSF pressure during or following endoscopic repair. A common area of involvement is a pneumatized lateral recess of the sphenoid (LRS) sinus, where prolonged intracranial pressures lead to arachnoid pits and subsequent development ...
Sharifi Guive G Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
Acquired non-traumatic transethmoidal encephaloceles are very infrequent lesions that are generally caused by a tumor or hydrocephalus. As far as we know, there is no reported case of encephalocele after CSF diversion in the literature. We present a 25-year-old woman with hydrocephalus due to aquiductal stenosis who was treated with ...
Klarica Marijan M Department of Pharmacology and Croatian Institute for Brain Research, School of Medicine University of Zagreb, Zagreb, - - 2014
Intracranial hypertension is a severe therapeutic problem, as there is insufficient knowledge about the physiology of cerebrospinal fluid (CSF) pressure. In this paper a new CSF pressure regulation hypothesis is proposed. According to this hypothesis, the CSF pressure depends on the laws of fluid mechanics and on the anatomical characteristics ...
Desmond Mary E ME Department of Biology, Villanova University, Villanova, PA, - - 2014
Expansion of the hollow fluid-filled embryonic brain occurs by an increase in intraluminal pressure created by accumulation of cerebrospinal fluid (CSF). Experiments have shown a direct correlation between cavity pressure and cell proliferation within the neuroepithelium. These findings lead us to ask how mechanistically this might come about. Are there ...
Mulargia Francesco F Università degli Studi di Bologna, Dipartimento di Fisica e Astronomia, Viale Carlo Berti Pichat, 6/2- 40127 Bologna - - - 2014
The physical mechanism of the anthropogenic triggering of large earthquakes on active faults is studied on the basis of experimental phenomenology, i.e., that earthquakes occur on active tectonic faults, that crustal stress values are those measured in situ and, on active faults, comply to the values of the stress drop ...
Pirouzi Gh G Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, - - 2014
Socket is an important part of every prosthetic limb as an interface between the residual limb and prosthetic components. Biomechanics of socket-residual limb interface, especially the pressure and force distribution, have effect on patient satisfaction and function. This paper aimed to review and evaluate studies conducted in the last decades ...
Beschorner Kurt E - - 2013
Previous research on slip and fall accidents has suggested that pressurized fluid between the shoe and floor is responsible for initiating slips yet this effect has not been verified experimentally. This study aimed to (1) measure hydrodynamic pressures during slipping for treaded and untreaded conditions; (2) determine the effects of ...
Dicpinigaitis Peter V - - 2013
Loss of consciousness following cough was first described in 1876 as "laryngeal vertigo" Since then, several hundred cases of what is now most commonly termed cough syncope have been reported, often in association with various medical conditions. Some early authors assumed this entity to be a form of epilepsy, but ...
van der Pas Rob - - 2013
Objective/MethodsCushing's disease (CD) is often accompanied by hypertension. CD can be treated surgically and, given the expression of somatostatin subtype 5 and dopamine 2 receptors by corticotroph pituitary adenomas, pharmacologically. Indeed, we recently observed that stepwise medical combination therapy with the somatostatin-analog pasireotide, the dopamine-agonist cabergoline and ketoconazole (which directly ...
Daouk Joël - - 2013
Normal-pressure hydrocephalus (NPH) and Alzheimer's disease (AD) have some similar clinical features and both involve white matter and cerebrospinal fluid (CSF) disorders. To compare putative relationships between ventricular morphology, CSF flow, and white matter diffusion in AD and NPH. Thirty patients (18 with AD and 12 with suspected NPH) were ...
Hassan Kaukab M KM Department of Internal Medicine, Division of Neurology, Command Hospital, West Bengal University of Health Sciences, Alipore, Kolkata, West Bengal, India ; Division of Neurology, Command Hospital, West Bengal University of Health Sciences, Alipore, Kolkata, West Bengal, - - 2013
The diagnosis of spontaneous intracranial hypotension or cerebrospinal fluid (CSF) hypovolemia syndrome requires a high index of suspicion and meticulous history taking, demonstration of low CSF pressure and/or neuroimaging features. A 31-year-old male, presented with subacute onset moderate occipital and sub-occipital headaches precipitated by upright posture and relieved on recumbency ...
Alkins Ryan R Physical Sciences Platform, Sunnybrook Research Institute, Toronto; - - 2013
Transcranial focused ultrasound is increasingly being investigated as a minimally invasive treatment for a range of intracranial pathologies. At higher peak rarefaction pressures than those used for thermal ablation, focused ultrasound can initiate inertial cavitation and create holes in the brain by fractionation of the tissue elements. The authors investigated ...
Stocker Sean D - - 2013
Excess dietary salt intake is a major contributing factor to the pathogenesis of salt-sensitive hypertension. Strong evidence suggests that salt-sensitive hypertension is attributed to renal dysfunction, vascular abnormalities, and activation of the sympathetic nervous system. Indeed, sympathetic nerve transections or interruption of neurotransmission in various brain centers lowers arterial blood ...
Geeraerts Thomas - - 2013
Optic nerve sheath diameter enlargement measured by ultrasound is known to be associated with raised intracranial pressure (ICP). Magnetic resonance imaging (MRI) of the cerebrospinal fluid (CSF) surrounding the optic nerve has been found, in an elegant study published in Critical Care, to correlate well with lumbar CSF opening pressure, ...
Zhang Zheng - - 2013
To assess whether a Valsalva manoeuver influences intra-ocular pressure (IOP), cerebrospinal fluid pressure (CSF-P) and, by a change in the trans-laminar cribrosa pressure difference, optic nerve head morphology. In the first part of the study, 20 neurological patients (study group 'A') underwent measurement of IOP and lumbar CSF-P measurement in ...
Kotake Yoshifumi - - 2013
This prospective observational study compared the volume effect between hydroxyethyl starch (HES) and crystalloid solution and its context dependency in intraoperative goal-directed fluid management. With institutional review board (IRB) approval, 35 patients undergoing major gastrointestinal surgery were enrolled. Fluid challenge consisting of 250 ml of either bicarbonate Ringer solution (BRS) or ...
- - 2013
A short-cut review was carried out to determine whether cerebrospinal fluid (CSF) opening pressure is significantly affected by the patient's leg position during the procedure. A total of 1410 papers was found using the reported search, of which five were considered relevant to the three-part question. The author, date and ...
Bono Francesco - - 2013
Riggeal et al.(1) found no correlation between the degree of transverse sinus stenosis (TSS) and the clinical course in idiopathic intracranial hypertension (IIH). There is no direct evidence of normalization of the CSF pressure in this series and this demonstration is needed to support their observation. The authors did not ...
Guo Yinghua - - 2013
Pulmonary arterial hypertension (PAH) is characterized by a progressive increase in pulmonary arterial pressure and vascular resistance. Despite advances in therapy for PAH, its treatment and prognosis remain poor. We aimed to investigate whether the transplantation of bone marrow mesenchymal stem cells (MSCs) overexpressing hepatocyte growth factor (HGF), alone or ...
Matsumae Mitsunori - - 2013
Object New approaches for understanding CSF motion in healthy individuals and patients with hydrocephalus and Chiari malformation are presented. The velocity and the pressure gradient of CSF motion were determined using phase contrast (PC) MRI. Methods The authors examined 11 healthy control subjects and 2 patients (1 with hydrocephalus and ...
Hardwick Lisa M - - 2013
A scientific rationale is proposed for establishment of acceptance criteria for leak rates in pharmaceutical freeze dryers. A method was developed to determine the quantity of air that could leak into any lyophilizer from the outside while still maintaining Class 100 / Grade A microbial conditions. A lyophilizing product is ...
Xie Xiaobin - - 2013
The orbital subarachnoid space surrounding the optic nerve is continuous with the circulation system for cerebrospinal fluid (CSF) and can be visualized using magnetic resonance imaging (MRI). We hypothesized that the orbital subarachnoid space width (OSASW) is correlated with and can serve as a surrogate for intracranial pressure (ICP). Our ...
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