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Cohen P G - - 1986
Headaches may occur in as many as 25% of hypertensive patients and generally bears little relationship to level of diastolic blood pressure. Previous observations, in normotensive patients, suggested that abnormalities in both potassium and ammonia metabolism might be related to the pathogenesis of these headaches. The present study was undertaken ...
Trimarco B - - 1986
We studied the response of forearm vascular resistance to lower body negative pressure (LBNP) at -10 and -40 mmHg in seven established hypertensives with left ventricular hypertrophy (LVH) and seven age-matched normotensive controls. To evaluate the specific role of ventricular baroreceptors, we also investigated the effects of propranolol on the ...
Mehta S K - - 1986
Borderline hypertensives who demonstrate tachycardia have a tendency toward the development of essential hypertension. However, the documentation of tachycardia in previous studies has been generally based on brief periods of observation. In the present study, we measured heart rates through a 24-hour period in 16 ambulatory mildly hypertensive subjects (ages ...
Andrejak M - - 1986
The purpose of the study was to compare the renal effects of low doses of exogenous dopamine to assess the responsiveness of renal dopaminergic receptors in normotensive and hypertensive subjects. Eight hypertensive patients and seven normotensive volunteer subjects were studied. Inulin and para-aminohippuric (PAH) clearances, natriuresis, and fractional excretion of ...
Guazzi M D - - 1986
Pulmonary pressure and arteriolar resistance are elevated in uncomplicated primary systemic hypertension. This study was carried out in 16 men with this form of hypertension and in 9 healthy men to compare 1) their pulmonary vascular reactivity to endogenous catecholamines released during mental arithmetic and cold pressor tests, and 2) ...
Morgan D B - - 1986
Sodium-dependent lithium efflux was measured in erythrocytes from 399 factory workers and 125 patients attending a hypertension clinic. Thirty-two factory workers had unsuspected essential hypertension (diastolic blood pressure phase V greater than 90 mmHg). These subjects had the same average erythrocyte lithium efflux as those with normal blood pressure, whereas ...
Meyer F U - - 1986
Hypertensive patients are an important group in dental treatment. In a prospectively randomised study the influence of 4 ml lidocaine 2% plain or with epinephrine 1:100,000 or norepinephrine 1:20,000 on heart rate and blood pressure before, during and after a small surgical intervention (tooth extraction) was investigated in a normotensive ...
Ewart C K - - 1986
An exaggerated blood pressure response to mental stress is believed to characterize young adults with genetic risk of essential hypertension, suggesting that stress-induced changes might provide a useful index of pathogenetic processes. We explored this by studying pressor responsivity to competitive tasks in adolescents drawn from a large urban population. ...
Guazzi M D - - 1986
Among patients with primary systemic hypertension pressure and arteriolar resistance in the pulmonary circulation exceed normal values and are hyper-reactive to sympathetic stimulation. A study was therefore carried out in 16 patients with uncomplicated essential hypertension and nine healthy subjects to compare the pulmonary vascular reactivity to exogenous catecholamines. In ...
Cappuccio F P - - 1986
We studied the effect of plasma from 12 patients with essential hypertension and 12 normotensive subjects on the contractile response to norepinephrine in human isolated arterial spiral strips. Human mesenteric and uterine arteries were obtained during abdominal surgery; they were cut into spiral strips and set up in isolated organ ...
M'Buyamba-Kabangu J R - - 1986
Blood pressure and anthropometric characteristics were studied in a 10% random sample (n = 675) of Bantu, aged greater than or equal to 10 years and living in an urban quarter of Kinshasa, Zaïre. The prevalence and awareness of hypertension as well as the therapeutic situation in adult participants aged ...
Snell J - - 1986
The effects of sino-aortic denervation (SAD) on cardiac noradrenaline stores, turnover and neuronal re-uptake were examined in normotensive rabbits and rabbits with two-kidney, two wrapped hypertension. Ten to 12 days after SAD, left ventricular (LV) noradrenaline stores were reduced in renal hypertensives to 43% of that of the sham-operated rabbits, ...
Elias M F - - 1986
This study was designed to compare changes in performance on selected measures from the Halstead-Reitan neuropsychological test battery over a 5 to 6 year interval for normotensive and medically treated, uncomplicated essential hypertensive adults. Mean performance level was poorer for hypertensive than for normotensive groups on an average impairment index ...
King H E - - 1986
Systematic ratings were made on the Tulane Test-Behavior Scale of the global and integrated behaviors observable for hypertensive and normotensive subjects as they worked to complete a battery of neuropsychological tests--the degree of attention and effort displayed, for example, self-confidence and self-criticism. The results for 82 subjects (41 subject pairs ...
M'Buyamba-Kabangu J R - - 1986
Blood pressure and intraerythrocyte sodium and potassium concentration were investigated in 59 male inhabitants of an urban quarter of Kinshasa, aged 10 years and older. Two subjects were excluded because they were on antihypertensive treatment. Seventeen subjects were normotensive with both parents normotensive (group 1); 9 subjects were normotensive with ...
Aoki K - - 1986
Hemodynamic changes in the supine resting position were investigated in 70 male subjects, consisting of 15 healthy volunteers with normotension (blood pressure of 113 +/- 7/70 +/- 5 mmHg, M +/- SD), 25 patients with borderline essential hypertension (143 +/- 12/90 +/- 6 mmHg) and 30 patients with established essential ...
Bohlin G - - 1986
Cardiovascular and neuroendocrine reactivity during arithmetic task performance were studied in 24 patients with borderline hypertension and normotensive controls. Personal control (self-paced versus externally paced performance) resulted in an attenuated blood pressure (BP) response to task performance in normotensives but not in borderline hypertensives. In response to self-paced work, systolic ...
Svensson A - - 1986
Fifty-four children aged 10-15 years were studied. Twenty-two children had mothers who had sustained hypertension after a hypertensive pregnancy (HT) and 17 had normotensive mothers who had previously had a hypertensive pregnancy (NT). A control group consisted of 15 children with normotensive mothers (C). Blood pressure was significantly higher in ...
Bing R F - - 1986
The relationship between leukocyte ionized calcium concentration, sodium content, and blood pressure was studied in normotensive subjects with (n = 17) and without (n = 21) a family history of hypertension and in untreated patients with essential hypertension (n = 22). There was a highly significant correlation between intracellular ionized ...
Lindholm L - - 1986
The levels of N-acetoxy-2-acetylaminofluorene (NA-AAF)-induced unscheduled DNA synthesis (UDS) were determined in resting mononuclear leukocytes from males in a geographically defined population. The mutagen sensitivity, as determined by the NA-AAF method, was associated with the risk indicators of cerebrocardiovascular disease (CCVD) rather than with CCVD itself. Thus, high blood pressure, ...
Low J M - - 1986
Arterial pressure and plasma catecholamine concentrations were measured in 16 normotensive and 10 hypertensive patients undergoing elective vascular surgery. Following induction of anaesthesia, both arterial pressure and plasma noradrenaline concentrations decreased in both groups. Following laryngoscopy, there was a moderate increase in arterial pressure in both normotensive and hypertensive patients. ...
Sagnella G A - - 1986
The effect of plasma from normotensive and hypertensive subjects on the binding of [3H]ouabain on human erythrocytes was investigated. The binding of [3H]ouabain on human erythrocytes was saturable and highly specific; linear Scatchard plots indicated the presence of a single type of binding site. Human plasma decreased the binding of ...
Rahman M - - 1986
We measured ouabain-sensitive and ouabain-resistant Na-K-adenosine triphosphatase (ATPase) activity in the red cells of 25 normotensive (average mean blood pressure [BP] 90.2 +/- 1.27 mm Hg) and 29 hypertensive subjects (average mean BP 115.3 +/- 2.45 mm Hg). Intracellular Na and K content were measured in 13 of the normotensive ...
Schütz W - - 1986
The reactivity of the sympathetic nervous system was studied in 10 young, adult patients with labile hypertension and compared with a normotensive age-matched control group. Upon graded exercise on a constant speed bicycle ergometer, the hypertensive subjects reacted with an exaggerated blood pressure response and a significantly greater increase in ...
Littler W A - - 1986
Plethysmographic blood flow records made shortly after venous occlusion of the forearm showed a biphasic response, first vasodilator then vasoconstrictor, in both normotensive and hypertensive subjects. The vasodilator component of this response was significantly lower in hypertensive than in normotensive subjects, whereas the vasoconstrictor component was identical. The decreased vasodilator ...
Schmieder R E - - 1986
In this article, the most important risk factors that may predict the transition from borderline to established hypertension are reviewed. Primary prevention has to focus on identifying individuals who are at highest risk and delaying or reversing further elevation of arterial pressure levels. A review of the literature indicates that ...
Ito N - - 1986
Maximal vasodilator capacity of resistance vessels has been shown to be reduced in normotensive young men with a family history of hypertension. The present study attempted to examine whether venous distensibility is decreased in normotensive men with hypertensive relatives. The venous pressure-volume relationship was determined in the forearm with a ...
Novo S - - 1986
A significant reduction of maximal vasodilation capacity at the calf in relation to the severity of the hypertensive state has been demonstrated in essential hypertension. The aim of this study was to evaluate the behavior of calf blood flow and vascular resistance in borderline hypertensives (BH) in comparison with normotensive ...
Nami R - - 1986
Systolic and diastolic blood pressure, heart rate, and circulating levels of catecholamines and cyclic AMP were measured during the handgrip test in 18 borderline hypertensive patients, 22 stable hypertensive patients, and 20 normotensive control subjects. No difference was observed, at rest, for plasma levels of noradrenaline, adrenaline, dopamine, and cyclic ...
Perkins K A - - 1986
Cardiovascular reactivity to video game and mental arithmetic stressors was compared among three groups of men: aerobically trained mild hypertensives, untrained mild hypertensives, and a comparison group of untrained normotensives. Relative to the untrained hypertensives, the trained hypertensives reacted to the video game with marginally smaller systolic blood pressure and ...
Schulte W - - 1986
Cardiovascular reactivity to mental stress was studied in 41 male borderline hypertensives in comparison with 37 male normotensives of the same age. In addition to a higher near-basal blood pressure, the borderline hypertensive group showed stronger absolute and percentage increases of systolic and diastolic blood pressure during stress. The increases ...
Eisenberg B M - - 1986
The aim of the study was to test whether there are typical changes in haemodynamics and humoral regulation in untreated hypertensives compared to normotensives with acute lowering of blood pressure (and venous return) induced by nitroglycerin (NTG). 23 hypertensives were investigated by radiocardiography and microcatheterization of the pulmonary artery as ...
Ambrosioni E - - 1986
In this article, we review the data about Na+ and K+ lymphocyte content in young subjects with borderline hypertension. These data indicate that many borderline subjects have an abnormally high lymphocyte Na+ content (Nai) and that their pressor response to stress and exercise is directly related to Nai. Lymphocyte K+ ...
Borghi C - - 1986
Forty-four young subjects with borderline hypertension underwent a 5-year follow-up. At the first examination their intralymphocytic Na+ (Nai) was measured before and after 1 month of a low-salt diet. Blood pressure and heart rate were recorded at rest (baseline), during mental arithmetic, and after the test (recovery). After 5 years, ...
Morton J J - - 1986
The role of vasopressin in human hypertension was examined in a series of studies. In patients with primary hyperaldosteronism and benign essential hypertension, circulating vasopressin was generally lower than in normotensive subjects. In contrast, plasma vasopressin was increased (p less than 0.001) in patients with malignant-phase hypertension. However, compared to ...
Jern S - - 1986
Patients with borderline hypertension tend to suppress expression of anger and hostility. However, if anything, they are psychologically hyperresponsive. The blood pressure elevation is maintained neurogenically in many with borderline hypertension. Consequently, it is tempting to postulate that suppressed anger causes neurogenic increases in blood pressure. Available data are inadequate ...
Radice M - - 1986
It has been suggested that the heart plays an active role in the pathogenesis of arterial hypertension. If this is true, there must be early cardiac involvement in young normotensive subjects who develop hypertension later in life and differences in cardiac morphology or function may exist between young normotensive subjects ...
Hjemdahl P - - 1986
The effects of circulating adrenaline on cardiovascular function were studied in 14 subjects with borderline hypertension (BHT) and in 14 matched normotensive controls. Adrenaline was infused in stepwise increasing doses (0.1, 0.2, 0.4, and 0.8 nM/kg/min, i.v.). Noninvasive measurements of cardiac function (M-mode echocardiography) and blood pressure and blood sampling ...
Lund-Johansen P - - 1986
This paper gives a review of cross-sectional and long-term hemodynamic studies in mild and borderline hypertension at different ages. Since the term borderline and mild are frequently used rather loosely, the selection criteria and blood pressure during the hemodynamic study should be noted. For two decades it has been assumed ...
Saito K - - 1986
Red cell membrane sodium permeability was studied in 41 untreated patients with essential hypertension (20 borderline hypertensives and 21 established hypertensives) and 21 age matched normotensive subjects by means of the measurement of unidirectional passive influx of 22Na+ into ouabain-treated erythrocytes. The mean value (+/- SD) of 22Na+ influx was ...
Falkner B - - 1986
Borderline hypertension generally describes blood pressure levels at the margins of an established disease state. Prior to adulthood, this definition becomes less clear. Juveniles with blood pressure levels at the extremes of the normal distribution may be borderline hypertensive, hypertensive, or normal. Aberrant mechanisms that progress to essential hypertension have ...
Mancia G - - 1986
This article reviews observations made on reflex control of circulation in essential hypertension and in a few models of experimental hypertension. It is emphasized that a wide consensus exists on the fact that baroreceptor control of heart rate is impaired in essential hypertension and that this occurs not only in ...
Perini C - - 1986
The effect of suppressed aggression on the reactivity of the sympathetic nervous and cardiovascular systems has been investigated in two groups of 24 subjects each with either borderline hypertension or normal blood pressure and no family history of hypertension. Groups were matched for sex and age (18-24 years). Suppressed aggression ...
Kagamimori S - - 1986
In female adolescents with a normal blood pressure range, the correlation between urinary sodium excretion and Na-K ATPase activity of erythrocyte membrane was investigated. 34 subjects with a family history of hypertension showed a significantly positive correlation between body mass index and mean blood pressure (r = 0.64, p less ...
Zimmerman B G - - 1985
The effect of diltiazem administered as a sustained infusion (10 to 15 micrograms/kg/min) was studied in 3 groups of conscious instrumented dogs: 4 normotensive, 5 Goldblatt hypertensive (GH) and 4 deoxycorticosterone acetate salt treated Goldblatt hypertensive (DSGH) dogs. Mean arterial blood pressure, left renal blood flow and heart rate were ...
Cléroux J - - 1985
Several lines of investigation suggest an abnormal sympathetic nervous activity (SNA) in hypertension. In an attempt to better evaluate SNA in a subgroup of hypertensive patients, free and sulpho-conjugated (conjugated) catecholamines (CA) [norepine-phrine (NE) and epinephrine (E)] were measured in plasma and red blood cells (RBC) of 10 labile hypertensive ...
Hossmann V - - 1985
Fifty-three untreated borderline hypertensives and 73 normotensives were randomly selected from 1342 adolescents (age range 23-27 years) who were examined in 1975, 1976 and 1980 in an epidemiological study. Blood pressure was 127.2 +/- 1.0/79.0 +/- 0.8 mmHg in normotensives and 147.2 +/- 1.6/93.7 +/- 1.1 mmHg in hypertensives (P ...
Brown M J - - 1985
The 24-h excretion of adrenaline and noradrenaline was measured in 268 untreated essential hypertensives and in 268 age- and sex-matched controls. No significant difference was found between the groups. However, in the control group alone, a multiple regression analysis showed a highly significant correlation between systolic blood pressure and both ...
Julius S - - 1985
This review shows that there is ample evidence of a stress-related hypersympathetic state in the early phase (borderline, hyperkinetic) of essential hypertension. These patients have signs of excessive autonomic cardiovascular drive (e.g. large changes in cardiac output, heart rate and pre-ejection period). After autonomic blockade these patients were also prone ...
Lutas E M - - 1985
To analyze cardiovascular dynamics in essential hypertension, 81 subjects with untreated mild essential hypertension (mean blood pressure, 112 +/- 14 mm Hg) and 87 normotensive subjects from the same working population were studied by echocardiography and simultaneous blood pressure determination. Hypertensive subjects had significantly higher pulse pressure, stroke volume index, ...
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