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De Weerdt S - - 2010
Both nasal continuous positive airway pressure (nCPAP) therapy and nose blowing can generate high pressures in the nose and sinuses. Nose blowing generates higher pressures than nCPAP therapy, but the duration of nCPAP therapy is considerably longer than the duration of nose blowing. Therefore, nCPAP could cause bone deformation. The ...
Rao Mohan - - 2010
Obstructive sleep apnea-hypoapnea syndrome (OSA) is a disorder that results in repetitive occlusion of the airway and hypoxemia during sleep. Epidemiologic studies have associated this disorder with increased cardiovascular morbidity and mortality. Systemic hypertension is prevalent among patients with OSA and has been recognized as a common identifiable cause of ...
Sofi Khalid - - 2010
This study was undertaken to find out the effect of early tracheostomy on weaning from mechanical ventilation. Pulmonary mechanics and arterial blood gases were assessed before and after tracheostomy in patients with severe head injury (Glasgow coma score < 8) requiring prolonged mechanical ventilation. The study included 20 mechanically ventilated ...
Morgenstern C C Institut de Bioenginyeria de Catalunya (IBEC), Dept. ESAII, Universitat Politècnica de Catalunya (UPC), Baldiri i Reixach 4, 08028, Barcelona, Spain. - - 2010
The differentiation of obstructive and central respiratory events is a major challenge in the diagnosis of sleep disordered breathing. Esophageal pressure (Pes) measurement is the gold-standard method to identify these events but its invasiveness deters its usage in clinical routine. Flattening patterns appear in the airflow signal during episodes of ...
Guo Zhong-Liang ZL Department of Respiratory Medicine, East Hospital, Tongji University School of Medicine, Shanghai 200120, China (Guo ZL, Ren T, Liang YJ); Pediatric Department, Zhongshan Hospital, Fudan University, Shanghai 200032, China (Cai YY); Pediatric ICU, Pediatrics Hospital, Fudan University, Shanghai 200032, China (Lu GP, Gong - - 2010
Low tidal volume mechanical ventilation is difficult to correct hypoxemia, and prolonged inhalation of pure oxygen can lead to oxygen poisoning. We suggest that continuous tracheal gas insufflation (TGI) during protective mechanical ventilation could improve cardiopulmonary function in acute lung injury. Totally 12 healthy juvenile piglets were anesthetized and mechanically ...
Eikermann M M Dept of Anesthesia and Critical Care, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114-2696, USA. - - 2010
We hypothesised that pentobarbital would improve upper airway mechanics based on an increase in latency to arousal and amplitude of the phasic genioglossus electromyogram (EMG), and a decrease in the active upper airway critical closing pressure (P(crit)). 12 healthy subjects received pentobarbital (100 mg) or placebo in a double-blind, crossover ...
Barbé Ferran F Coordinating Center, Institut de Recerca Biomèdica Lleida, Lleida, Spain. - - 2010
Continuous positive airway pressure (CPAP) is the current treatment for patients with symptomatic obstructive sleep apnea (OSA). Its use for all subjects with sleep-disordered breathing, regardless of daytime symptoms, is unclear. This multicenter controlled trial assesses the effects of 1 year of CPAP treatment on blood pressure (BP) in nonsymptomatic, ...
Ali Achmet - - 2009
BACKGROUND AND OBJECTIVE: The laryngeal mask airway (LMA) is an important airway device that was developed in 1983. From the first classic LMA models up to now, LMA models have been developed that are easily and quickly inserted, provide ventilation at higher airway pressures, have lower cuff pressure, a reduced ...
Koombua Kittisak - - 2009
Without proper knowledge of mechanical ventilation effects, physicians can aggravate an existing lung injury. A better understanding of the interaction between airflow and airway tissue during mechanical ventilation will be helpful to physicians so that they can provide appropriate ventilator parameters for intubated patients. In this study, a computational model ...
Owens Robert L RL Sleep Disorders Research Program, Div. of Sleep Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. - - 2010
Changes in end-expiratory lung volume (EELV) affect upper airway stability. The passive pharyngeal critical pressure (Pcrit), a measure of upper airway collapsibility, is determined using airway pressure drops. The EELV change during these drops has not been quantified and may differ between obese obstructive sleep apnea (OSA) patients and controls. ...
Agostoni Piergiuseppe - - 2010
It is unknown whether subclinical high-altitude pulmonary oedema reduces spontaneously after prolonged altitude exposure. Continuous positive airway pressure (CPAP) removes extravascular lung fluids and improves haemoglobin oxygen saturation in acute cardiogenic oedema. We evaluated the presence of pulmonary extravascular fluid increase by assessing CPAP effects on haemoglobin oxygen saturation under ...
von Goedecke A - - 2009
Despite being a standard procedure during induction of anaesthesia, facemask ventilation can be a major challenge especially for inexperienced anaesthetists. We manufactured a Jaw-Thrust-Device designed to keep the patient's jaws in an optimised position, and thus to maintain the airway in a permanently patent state. Using a cross over design, ...
Fischer Hendrik S - - 2009
OBJECTIVE: To investigate tidal volume (VT) and leak measurements during continuous positive airway pressure (CPAP) in neonates using a commercial ventilatory device equipped with a flow sensor at the Y-piece. DESIGN: Randomized cross-over trial. SETTING: Neonatal intensive care unit level III. PATIENTS: Thirty-two infants, median (range) birth weight 1,435 (710-2,730) ...
Uppal V - - 2009
BACKGROUND: The i-gel differs from other supraglottic airway devices, in that it has a softer, non-inflatable cuff. This study was designed to compare the performance of the i-gel and the LMA-Unique (LMA-U) when used during anaesthesia in paralysed patients. METHODS: Both devices were studied in 39 anaesthetized, paralysed patients in ...
Parke R - - 2009
BACKGROUND: The aim of this prospective study was to determine whether a level of positive airway pressure was generated in participants receiving nasal high flow (NHF) delivered by the Optiflow system (Fisher and Paykel Healthcare Ltd, Auckland, New Zealand) in a cardiothoracic and vascular intensive care unit (ICU). METHODS: Nasopharyngeal ...
Hill Kylie - - 2010
Answers were sought to the following question: Are techniques, applied predominantly with the aim of clearing secretions from the airways, to patients during an acute exacerbation of chronic obstructive pulmonary disease (AECOPD), safe and effective? A systematic review was undertaken of studies that (i) were either randomized controlled or randomized ...
Bellone Andrea - - 2009
OBJECTIVE: The objective of the study was to compare the effect of continuous positive airway pressure (CPAP) in patients with acute cardiogenic pulmonary edema (ACPE) with preserved or impaired left ventricular systolic function with regard to resolution time. METHODS: In a prospective, preliminary observational cohort study, 18 patients with preserved ...
Shimada Yuichi J - - 2009
We report a case of hypertrophic cardiomyopathy with recurrent ventricular tachycardia that resolved after initiating continuous positive airway pressure therapy.
Ayuse Takao T Department of Clinical Physiology, Nagasaki University Graduate School of Biomedical Science, 1-7-1 sakamoto, Nagasaki-shi 852-8588, Japan. - - 2009
Upper airway patency may be compromised during sleep and anesthesia by either anatomical alterations (mechanical properties) or disturbances in the neural control (compensatory neuromuscular responses). The pathophysiology of upper airway obstruction during anesthesia may differ between men and women. Recently, we reported that the upper airway mechanical properties were comparable ...
Sinha Aparna A Dept. of Anesthesia, Pain and Perioperative Medicine, Sir Ganga Ram Hospital, New Delhi, India. - - 2009
ProSeal LMA (PLMA), one of the advanced supraglottic devices has been successfully used to provide both spontaneous and controlled ventilation in children with upper respiratory tract infection (URTI). URTI does not imply restriction of disease to upper respiratory tract; it has been shown to produce pulmonary dysfunction. PEEP has been ...
Jose Riya - - 2012
Background: Hypoxemia complicating care during ventilation is a common problem. Objective: To describe an unusual cause of hypoxemia with fluctuating airway pressures in an invasively ventilated, organophosphate-poisoned patient. Case Report: A 40-year-old man being treated for organophosphate poisoning developed episodes of high airway pressure during mechanical ventilation. These episodes initially ...
Majumdar Arnab - - 2009
Airways that collapse during deflation generate a crackle sound when they reopen during subsequent reinflation. Since each crackle is associated with the reopening of a collapsed airway, the likelihood of an airway to be a crackle source is identical to its vulnerability to collapse. To investigate this vulnerability of airways ...
Cavus Erol - - 2009
BACKGROUND AND OBJECTIVE: EasyTube (EZT), ProSeal laryngeal mask airway (PLMA), and Laryngeal tube S II (LTS II) have recently been introduced as supraglottic airway devices and have been proposed as emergency airway alternatives. The purpose of this study was to compare the performance of the three devices, if used by ...
Lee A K Y - - 2009
The Laryngeal Mask Airway Supreme (LMAS) is a new, single-use laryngeal mask airway with gastric access. We conducted a randomised controlled study comparing the LMAS with the reusable ProSeal Laryngeal Mask Airway (PLMA) in 70 patients undergoing general anaesthesia with paralysis for gynaecological laparoscopic surgery. Our primary outcome measure was ...
Hertegonne Katrien - - 2010
In moderate to severe obstructive sleep apnea syndrome (OSAS), the use of Continuous Positive Airway Pressure (CPAP) is the gold standard therapy. In the last decade, new technologies such as auto-adjustable CPAP (APAP) have been promoted as having an added advantage over CPAP, because of their ability to adapt the ...
Hiel Deline - - 2009
OBJECTIVE: Exposure in connection with cleaning piggeries induces airway inflammation. The aim of this study was to compare the health effects related to two different cleaning processes in a piggery. METHODS: In a cross-over study design, 12 subjects were randomly exposed for three hours during the cleaning of a piggery ...
Spentzas Thomas - - 2009
High-flow nasal cannula (HFNC) therapy is a treatment for respiratory distress in neonates and children. In the present study, we assessed its effectiveness, comfort, and possible mechanism of action. METHODS: We reviewed records of 46 patients treated with HFNC and estimated the modified COMFORT score (7 to 35 units), the ...
Torre-Bouscoulet Luis - - 2009
to analyze the agreement between effective CPAP-determined on the basis of a 7-night auto-adjusting positive airway pressure (APAP) trial at home with that obtained through 5 different predictive equations. Data were collected from consecutive CPAP-naive patients with OSA who underwent a 7-night non-attended home-setting APAP trial. The 95th percentile APAP ...
Ihra Gerald C - - 2009
BACKGROUND: High-frequency jet ventilation (HFJV) can lead to high-airway pressures under certain conditions. In this laboratory study, we evaluated the influence of the injector's position relative to a fixed airway obstruction on peak pressures in a tracheal-lung model. METHODS: We administered HFJV via a metal jet injector at varying distances ...
Ansell Thomas K - - 2009
BACKGROUND AND OBJECTIVE: In adults, respiratory movements, such as tidal and deep breaths, reduce airway smooth muscle force and cause bronchodilation. Evidence suggests that these beneficial effects of oscillatory strain do not occur in children, possibly because of reduced coupling of the airways to lung tissue or maturational differences in ...
Oliveira W - - 2009
Obstructive sleep apnoea (OSA) has been reported as a predictor of left ventricle (LV) diastolic dysfunction and left atrium (LA) remodelling. The aim of this study is to evaluate the impact of OSA treatment with a continuous positive airway pressure device (CPAP) on the LA volume and function, as well ...
Edwards Bradley A - - 2009
Continous positive airway pressure (CPAP) is used to treat infant respiratory distress syndrome and apnea of prematurity, but its mode of action is not fully understood. We hypothesised that CPAP increases lung volume and stabilises respiratory control by decreasing loop gain (LG). Experimentally induced periodic breathing (PB) in the lamb ...
Gray A J - - 2009
To determine whether non-invasive ventilation reduces mortality and whether there are important differences in outcome by treatment modality. Multicentre open prospective randomised controlled trial. Patients presenting with severe acute cardiogenic pulmonary oedema in 26 emergency departments in the UK. Inclusion criteria were age > 16 years, clinical diagnosis of acute ...
Hillman David R - - 2009
BACKGROUND: Upper airway collapsibility is known to increase under anesthesia. This study assessed how this increase in collapsibility evolves during slow Propofol induction and how it relates to anesthesia-induced changes in upper airway muscle activity and conscious state. METHODS: Nine healthy volunteers were studied. Anesthesia was induced with Propofol in ...
do Nascimento Renata Medeiros - - 2009
Continuous positive airway pressure (CPAP) with prongs is the ventilatory support most used in newborns. Nasal injuries are complications that may arise due to the prolonged use of this device. This study aimed to determine the frequency of nasal injuries in newborns through the use of continuous positive airway pressure ...
Murri Mora - - 2009
Sleep apnea-hypopnea syndrome (SAHS) is characterized by recurrent episodes of hypoxia/reoxygenation, which seems to promote oxidative stress. SAHS patients experience increases in hypertension, obesity, and dyslipidemia, and the oxidative state has been related to the genesis of these disorders. The purpose of this study was to examine the changes in ...
Craig Sonya - - 2009
Obstructive sleep apnoea (OSA) is associated with cardiovascular morbidity and may precipitate cardiac dysrhythmias. Uncontrolled reports suggest that continuous positive airway pressure (CPAP) may reduce dysrhythmia frequency and resting heart rate. We undertook a randomised controlled trial of therapeutic CPAP and compared with a subtherapeutic control which included an exploration ...
Sai Sunil Kishore M M Division of Neonatology, Department of Pediatrics, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, - - 2009
To determine whether early nasal intermittent positive pressure ventilation (NIPPV), in comparison to early continuous positive airway pressure (CPAP), can reduce the need for intubation and mechanical ventilation in preterm neonates with suspected respiratory distress syndrome (RDS). In this stratified open-label randomized controlled trial, neonates (28-34 weeks gestation) with respiratory ...
Das Aneesa M - - 2009
Obstructive sleep apnea (OSA) is a common form of sleep-disordered breathing that occurs due to recurrent collapse of the upper airway with inspiration. Large epidemiologic studies have established that OSA is a risk factor for developing hypertension. The pathophysiologic mechanism of this relationship is due to the distinctive pattern of ...
Herbstreit Frank - - 2009
BACKGROUND: Residual neuromuscular blockade increases the risk to develop postoperative complications. The authors hypothesized that minimal neuromuscular blockade (train-of-four [TOF] ratio 0.5-1) increases upper airway collapsibility and impairs upper airway dilator muscle compensatory responses to negative pharyngeal pressure challenges. METHODS: Epiglottic and nasal mask pressures, genioglossus electromyogram, respiratory timing, and ...
Agarwal R - - 2009
INTRODUCTION: Noninvasive ventilation (NIV) with continuous positive airway pressure (CPAP) has been shown to decrease endotracheal intubation and mortality in patients with acute cardiogenic pulmonary oedema (ACPE). The Three Interventions in Cardiogenic Pulmonary Oedema showed no advantage of NIV over standard medical therapy. This meta-analysis is an update on the ...
Garcia Guilherme J M - - 2009
BACKGROUND: Interindividual variability in nasal filtration is significant due to interindividual differences in nasal anatomy and breathing rate. Two important consequences arise from this variation among humans. First, devices for nasal drug delivery may furnish quite different doses in the nasal passages of different individuals, leading to different responses to ...
Singh Ishwar - - 2009
Sixty ASA grade I & II adult patients of either sex were randomly assigned into two groups. Group I (n=30) for I-gel and Group P (n=30) for LMA - ProSeal. We assessed the airway sealing pressure, ease of insertion, success rate of insertion, ease of gastric tube placement, airway trauma ...
Micaglio M - - 2009
BACKGROUND: When compared with the Classic laryngeal mask airway (cLMA), the recently introduced ProSeal laryngeal mask airway (PLMA) has modified features to produce higher airway seal pressures and enable ventilation in circumstances where the cLMA might fail. The first neonatal size 1 PLMA recently became available. This study was designed ...
Hosten T - - 2009
BACKGROUND AND OBJECTIVE: The LMA-Supreme() (S-LMA()) is a new supraglottic airway device that presents combined features of flexibility, curved structure and single use and a different cuff structure. The purpose of this study was to compare the oropharyngeal leak pressures (OLP) of LMA-Proseal() (P-LMA()) and S-LMA(). METHODS: Sixty adult patients ...
Herff Holger - - 2009
BACKGROUND: The Smart Bag MO(R) is an adult flow-limited bag-valve device designed to reduce the risk of stomach inflation in an unprotected airway. Its properties in severe airway obstruction are as yet unknown. METHODS: In a bench model, we evaluated respiratory mechanics and delivered tidal volumes although ventilating at airway ...
Wallace C J - - 2009
Hyperinflation of the laryngeal mask airway cuff may exert high pressure on pharyngeal and laryngeal structures. In vitro data show that high intra cuff pressures may occur when inflated to only 30% of the manufacturer's recommended maximum inflation volume. We prospectively assessed the pressure volume curves of paediatric sized laryngeal ...
Rieder Marcelo de Mello Mde - - 2009
To investigate the feasibility and the cardiorespiratory effects of using positive expiratory airway pressure, a physiotherapeutic tool, in comparison with a T-tube, to wean patients from mechanical ventilation. A prospective, randomized, cross-over study. Two intensive care units. We evaluated forty patients who met weaning criteria and had been mechanically-ventilated for ...
Hui David S DS David S. Hui, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong, People's Republic of China. - - 2009
As part of our influenza pandemic preparedness, we studied the exhaled air dispersion distances and directions through two different face masks (Respironics; Murrysville, PA) attached to a human-patient simulator (HPS) during noninvasive positive-pressure ventilation (NPPV) in an isolation room with pressure of -5 Pa. The HPS was positioned at 45 ...
DiMarco Anthony F AF Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH, USA. - - 2009
Evaluation of the capacity of lower thoracic spinal cord stimulation (SCS) to activate the expiratory muscles and generate large airway pressures and high peak airflows characteristic of cough, in subjects with tetraplegia. Clinical trial. Inpatient hospital setting for electrode insertion; outpatient setting for measurement of respiratory pressures; home setting for ...
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