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Loring Stephen H SH http://orcid.org/0000-0002-6277-3979 Beth Israel Deaconess Medical Center - - 2014
Pneumoperitoneum for laparoscopic surgery is known to stiffen the chest wall and respiratory system, but its effects on resting pleural pressure in humans are unknown. We hypothesized that pneumoperitoneum would raise abdominal pressure, push the diaphragm into the thorax, raise pleural pressure and squeeze the lung, which would become stiffer ...
Fremuth Jiri J Pediatric intensive care unit (PICU), Department of Pediatrics, Faculty of Medicine, Charles University of Prague in Pilsen, Pilsen, Czech Republic - - 2014
Background: The aim of this comparative study was to assess the impact of two different settings of tidal volume (Vt) on the function and morphology of the mechanically ventilated lungs during a 12-h period. Materials and Methods: A total of 32 animals were randomly divided into two groups. Group A ...
Retamal Jaime - - 2014
IntroductionWhen alveoli collapse the traction forces exerted on their walls by adjacent expanded units may increase and concentrate. These forces may promote its re-expansion at the expense of potentially injurious stresses at the interface between the collapsed and the expanded units. We developed an experimental model to test the hypothesis ...
Potkay Joseph A JA VA Ann Arbor Healthcare System, Ann Arbor, MI 48105, USA. - - 2014
Microfluidic or microchannel artificial lungs promise to enable a new class of truly portable, therapeutic artificial lungs through feature sizes and blood channel designs that closely mimic those found in their natural counterpart. These new artificial lungs could potentially: 1) have surface areas and priming volumes that are a fraction ...
Guler Hasan H Department of Electrical-Electronics Engineering, Faculty of Engineering, Firat University, Elaziğ, Turkey - - 2014
The aim of this article is to develop a knowledge-based therapy for management of rats with respiratory distress. A mechanical ventilator was designed to achieve this aim. The designed ventilator is called an intelligent mechanical ventilator since fuzzy logic was used to control the pneumatic equipment according to the rat's ...
Ziebart Alexander - - 2014
BackgroundIn moderate acute respiratory distress syndrome (ARDS) several studies support the usage of assisted spontaneous breathing modes. Only limited data, however, focus on the application in systemic sepsis and developing lung injury. The present study examines the effects of immediate initiation of pressure support ventilation (PSV) in a model of ...
Blakeman Thomas T University of Cincinnati Department of Surgery, Division of Trauma and Critical Care , Cincinnati, OH , - - 2014
Abstract Purpose: Early ambulation in the ventilated patient is gaining wider acceptance. We evaluated a new portable (1 lb), gas powered, volume ventilator designed for NIV via a proprietary nasal pillows interface (Breathe Technologies, CA). We developed a model to approximate a patient's nose, upper airway and trachea. The model ...
Carlson Jestin N - - 2014
ABSTRACTObjective:Pulmonary aspiration of gastric contents occurs 20 to 30% of the time during cardiopulmonary resuscitation (CPR) of cardiac arrest due to loss of protective airway reflexes, pressure changes generated during CPR, and positive pressure ventilation (PPV). Although the American Heart Association has recommended the laryngeal mask airway (LMA) as an ...
Ruberto Franco F F Dipartimento di Anestesia e Rianimazione, UOD Anestesia e Terapia Intensiva Trapianti d'Organo, Policlinico Umberto I, "Sapienza", Rome, - - 2014
Independent lung ventilation (ILV) is a ventilation strategy used in patients with significant differences in respiratory mechanics between the 2 lungs owing to asymmetric or unilateral lung diseases. We report the case of a 66-year-old patient treated with ILV for a primary graft dysfunction occurred early after single lung transplantation. ...
Vargas Maria M Department of Neuroscience and Reproductive and Odontostomatological Sciences, University of Naples "Federico II," Naples, Italy; - - 2014
Percutaneous dilational tracheostomy is normally a bronchoscope-guided procedure. The insertion of a bronchoscope into an endotracheal tube (ETT) affects resistance, flow, and alveolar pressure. To improve airway management and ventilation during percutaneous tracheostomy, we developed a double lumen endotracheal tube (DLET). The aim of this in vitro study was to ...
Carvalho Nadja C NC 1Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Dresden, Technische Universität Dresden, Dresden, Germany. 2Department of Electronic Engineering, Federal University of Minas Gerais, Belo Horizonte, Brazil. 3Institute for Medical Informatics and Biometry, Technische Universität Dresden, Dresden, Germany. 4Institute of Anatomy, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. 5Laboratory of Pulmonary Investigation, Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.. 6Department of Surgical Sciences and Integrated Diagnostics, IRCCS San Martino Hospital, University of Genoa, Genoa, - - 2014
To assess the effects of different levels of spontaneous breathing during biphasic positive airway pressure/airway pressure release ventilation on lung function and injury in an experimental model of moderate acute respiratory distress syndrome. Multiple-arm randomized experimental study. University hospital research facility. Thirty-six juvenile pigs. Pigs were anesthetized, intubated, and mechanically ...
Hong Sung Ok SO From the Departments of *Oral Maxillofacial Surgery and †Anesthesiology and Pain Medicine, School of Medicine, Kyung Hee University Dental Hospital at Gangdong, Kyung Hee University, Seoul, Republic of - - 2014
Perioperative pulmonary edema is a rare complication of maxillofacial surgery. However, this potentially fatal complication may arise during any maxillofacial surgery. Negative pressure pulmonary edema can be caused by upper airway obstruction after operation. When this phenomenon arises, if not treated properly, it progresses rapidly causing fatal outcomes. Because orthognathic ...
Wirth Steffen S Division of Experimental Anesthesiology, Department of Anesthesiology and Intensive Care Medicine, University Medical Center, Hugstetter Straße 55, Freiburg, Germany. Electronic address: - - 2014
Recently, we presented Flow Controlled Expiration (FLEX) as a new option for lung-protective ventilation. FLEX delays the expiratory volume decrease in the lungs without prolonging the duration of expiration. Most ventilated patients nowadays receive spontaneous breathing support. We investigated whether FLEX is tolerated by awake subjects. In 24 healthy subjects ...
Stanzi Alessia A Laboratory for Experimental Thoracic Surgery, Department of Clinical and Experimental Medicine, KU Leuven University, Leuven, Belgium; Department of Thoracic Surgery, Ospedale Maggiore Policlinico, University of Milan, Milan, - - 2014
After normothermic ex vivo lung perfusion (EVLP), pulmonary grafts are usually flush-cooled and stored on ice until implantation although evidence for this practice lacks. We compared outcomes between 2 post-EVLP preservation strategies in a porcine left single-lung transplantation model. After cold flush and 2-h EVLP, donor lungs were prepared and split. ...
Bakhshesh Morteza M Department of Physiology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. - - 2014
Nasal mucosa has an extraordinary nerve supply with unique geometry that encompasses complex physiology. Among these, side-specific predilections to the respiratory and autonomic centers are the interesting issues that have been raised about the consequences of the nasal irritations. The aim of the study was an evaluation of how intranasal ...
Hartland Benjamin L - - 2014
Awake, spontaneously breathing humans sigh on average 9 to 10 times per hour. The sigh is a normal homeostatic reflex proposed to maintain pulmonary compliance and decrease the formation of atelectasis by recruiting collapsed alveoli. The induction and maintenance of anesthesia with muscle paralysis and a fixed tidal volume abolish ...
Hubmayr Rolf D RD Department of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota. - - 2014
In the following perspective, we will highlight seemingly remote, downstream consequences of common ventilator management decisions. For example, a change in PEEP may alter venous return, blood pressure, cardiac output, arterial and venous blood gas tensions, metabolic rate, respiratory sensations, breathing pattern, and the work of breathing. If providers consider ...
Lavoisier Pierre P P. Lavoisier, PT, MD, Centre d'Etudes des Dysfonctions Sexuelles (CEDS), 153 Rue Pierre Corneille 69003, Lyon, - - 2014
In men, involuntary or voluntary ischiocavernosus muscle contractions after erection lead to intracavernous blood pressures far higher than the systolic pressure, which builds and maintains penile rigidity. Thus, erectile dysfunction may be partly due to ischiocavernosus muscle atrophy and treated by rehabilitation interventions. Determine whether pelvic floor muscle strengthening interventions ...
Smith Andrea L AL Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, - - 2014
Lung lobectomy is necessary in neonatal patients for the treatment of a variety of congenital bronchopulmonary malformations. The working space required for traditional stapling devices limits their use in pediatric video-assisted thoracoscopic (VATS) lung lobectomy. The use of Hem-o-lok clips (Teleflex Medical Inc. Research Triangle Park, NC) has been described ...
Izumi Hideaki H Department of Urology, Tohoku University Graduate School of Medicine, 1-1 Seiryomachi, Aoba-ku, Sendai, 980-8574, - - 2014
Effects of tadalafil, a phosphodiesterase type 5 inhibitor, on the urethral continence reflex induced by sneezing were investigated. The amplitude of urethral pressure responses during sneezing (A-URS) and urethral baseline pressure (UBP) were measured in female rats using a microtransducer-tipped catheter. Sneeze leak-point pressure (S-LPP), defined as the lowest amount ...
Titze Ingo R IR National Center for Voice and Speech, 136 South Main Street, Suite 320, Salt Lake City, Utah - - 2014
The origin of vocal registers has generally been attributed to differential activation of cricothyroid and thyroarytenoid muscles in the larynx. Register shifts, however, have also been shown to be affected by glottal pressures exerted on vocal fold surfaces, which can change with loudness, pitch, and vowel. Here it is shown ...
Ludolph Ingo I Department of Plastic and Hand Surgery and Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital of Erlangen, Friedrich-Alexander-University of Erlangen-Nuernberg, Erlangen, - - 2014
The aim of this article is to improve the treatment of patients with complete skin loss of the penile shaft after Fournier's gangrene or hidradenitis suppurativa using modern biomatrices and topical negative pressure therapy. From January 2010 to December 2011, three patients with Fournier's gangrene or hidradenitis suppurativa were treated. ...
Saaby Marie-Louise ML Sorgenfrigaardsvej 108b, 2800 Lyngby, Denmark. - - 2014
Stress urinary incontinence (SUI) occurs when the bladder pressure exceeds the urethral pressure in connection with physical effort or exertion or when sneezing or coughing and depends both on the strength of the urethral closure function and the abdominal pressure to which it is subjected. The urethral closure function in ...
Shi Yan Y School of Automation Science and Electrical Engineering, Beihang University, Beijing 100191, China ; The State Key Laboratory of Fluid Power Transmission and Control, Zhejiang University, Hangzhou 310058, China ; Department of Mechanical Engineering, University of Bath, Bath BA2 7AY, - - 2014
Mechanical ventilation is an important life support treatment of critically ill patients, and air pressure dynamics of human lung affect ventilation treatment effects. In this paper, in order to obtain the influences of seven key parameters of mechanical ventilation system on the pressure dynamics of human lung, firstly, mechanical ventilation ...
Goikoetxea Estibalitz E Research Unit for Experimental Neonatal Respiratory Physiology, Cruces University Hospital, Barakaldo, Bizkaia, Spain; Thermal and Fluids Engineering Division, Mechanical Engineering Department, TECNUN, University of Navarra, San Sebastian, Gipuzkoa, - - 2014
Aerosol delivery holds potential to release surfactant or perfluorocarbon (PFC) to the lungs of neonates with respiratory distress syndrome with minimal airway manipulation. Nevertheless, lung deposition in neonates tends to be very low due to extremely low lung volumes, narrow airways and high respiratory rates. In the present study, the ...
Beda Alessandro A Pulmonary Engineering Group, Clinic of Anaesthesiology and Intensive Care Therapy, University Hospital Dresden, Technische Universität Dresden, Dresden, Germany; Department of Electronic Engineering and Postgraduate Program of Electrical Engineering, Federal University of Minas Gerais, Pampulha, Belo Horizonte, - - 2014
Measuring esophageal pressure (Pes) using an air-filled balloon catheter (BC) is the common approach to estimate pleural pressure and related parameters. However, Pes is not routinely measured in mechanically ventilated patients, partly due to technical and practical limitations and difficulties. This study aimed at comparing the conventional BC with two ...
Suzuki Atsushi A Department of Respiratory Medicine and Allergy, Tosei General Hospital, Seto, Aichi, - - 2014
Lung-dominant connective tissue disease (LD-CTD) is a new concept for classifying the subset of patients with interstitial pneumonia who have clinical features suggesting an associated CTD, but whose features fall short of a clear diagnosis of CTD under the current rheumatologic classification systems. The impact of mean pulmonary arterial pressure ...
Machado Humberto S HS Serviço de Anestesiologia, Centro Hospitalar do Porto, Largo Abel Salazar, Porto, 4099-001 - - 2014
Mechanical ventilation is a well-known trigger for lung inflammation. Research focuses on tidal volume reduction to prevent ventilator-induced lung injury. Mechanical ventilation is usually applied with higher than physiological oxygen fractions. The purpose of this study was to investigate the after effect of oxygen supplementation during a spontaneous ventilation set ...
Ferrando Carlos C Anesthesiology and Critical Care Department, Hospital Clínico Universitario of Valencia, Av. Blasco Ibañez, 17, CP: 46010 Valencia, - - 2014
Historically, the elective ventilatory flow pattern for neonates has been decelerating flow (DF). Decelerating flow waveform has been suggested to improve gas exchange in the neonate when compared with square flow (SF) waveform by improving the ventilation perfusion. However, the superiority of DF compared with SF has not yet been ...
Camilo Luciana M LM Laboratory of Respiration Physiology, Carlos Chagas Filho Institute of Biophysics, Universidade Federal do Rio de Janeiro, Rio de Janeiro, - - 2014
Variable ventilation (VV) seems to improve respiratory function in acute lung injury and may be combined with positive end-expiratory pressure (PEEP) in order to protect the lungs even in healthy subjects. We hypothesized that VV in combination with moderate levels of PEEP reduce the deterioration of pulmonary function related to ...
Fahlman Andreas A Life Sciences, Texas A&M University-Corpus Christi Corpus Christi, TX, - - 2014
We examined structural properties of the marine mammal respiratory system, and tested Scholander's hypothesis that the chest is highly compliant by measuring the mechanical properties of the respiratory system in five species of pinniped under anesthesia (Pacific harbor seal, Phoca vitulina; northern elephant seal, Mirounga angustirostris; northern fur seal Callorhinus ...
- - 2014
[This corrects the article DOI: 10.1371/journal.pone.0107736.].
Tong Kim - - 2013
To describe (1) the radiographic appearance of intact hydraulic urethral sphincters (HUS) and (2) the success of leak detection using clinically feasible methods. Prospective, blinded in vitro study. Thirty HUS devices (10 each of 8, 10, and 12 mm diameter sizes). All devices were inflated with saline (0.9% NaCl) solution to ...
Lee J H - - 2013
A recording of the intracavernosal pressure (ICP) in conscious rats using telemetry has the advantage of being able to evaluate erection under physiological conditions. The aim of this study was to determine whether the radiotelemetric assessment of ICP in apomorphine-induced erection is appropriate for assessing erectile function in an animal ...
Corona-Quintanilla Dora L - - 2013
AIM: To evaluate the role of pelvic and perineal striated muscles on urethral function during micturition. METHODS: Pubococcygeus, or both bulbospongiosus and ischiocavernosus muscles were electrically stimulated during the voiding phase of micturition, and bladder and urethral pressure were simultaneously recorded in urethane anesthetized female rabbits. Bladder and urethral function ...
Schloss Brian B Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, Ohio, United - - 2013
To improve surgical visualization and facilitate the procedure, one-lung ventilation (OLV) is frequently used during thoracic surgery. Although generally well tolerated, the ventilation-perfusion inequality induced by OLV may lead to a decrease in oxygenation and, at times, hypoxemia. Effective treatment algorithms and strategies are necessary for the treatment of hypoxemia ...
Wang Zhihong - - 2013
We investigated the dependence of electromechanical coupling and the piezoelectric response of a micromachined Pb(Zr0.52Ti0.48)O3 (PZT) diaphragm on its curvature by observing the impedance spectrum and central deflection responses to a small AC voltage. The curvature of the diaphragm was controlled by applying air pressure to its back. We found ...
Carvell James J Paediatric Department, Heartlands Hospital, Birmingham, UK - - 2013
This report outlines the case of a 3-year-old boy whose initial presentation was that of asymptomatic hypertension (lowest recording 148/90), found at preoperative check prior to stage 2-correction surgery for distal hypospadias. Upon diagnosis of true hypertension, an ultrasound of the child's renal tract showed evidence of marked hydronephrosis and ...
Jesus L E - - 2012
OBJECTIVE: Abnormal uroflowmetries are common after tubularized incised plate urethroplasties (TIP), perhaps due to low compliance. We hypothesized that (1) abnormal uroflowmetries after TIP might be caused by segmental lower compliance; (2) by adding a graft to the raw area in the incised plate (TIPG), compliance might be improved by ...
Anusionwu Ifeanyi - - 2012
PURPOSE: We compared cuff sites and assessed anatomical and manometric differences between the transscrotal and perineal approaches to artificial urinary sphincter placement in fresh male cadavers. MATERIALS AND METHODS: Artificial urinary sphincter implantation using perineal and transscrotal incisions was performed in 15 fresh male cadavers. The artificial urinary sphincter cuffs ...
Ishimatsu Naoki - - 2012
Nano-polycrystalline diamond (NPD) [Irifune et al. (2003), Nature (London), 421, 599] has been used to obtain a glitch-free X-ray absorption spectrum under high pressure. In the case of conventional single-crystal diamond (SCD) anvils, glitches owing to Bragg diffraction from the anvils are superimposed on X-ray absorption spectra. The glitch has ...
Hannah Daniel C - - 2012
A lack of consensus persists regarding the origin of photoluminescence in silicon nanocrystals. Here we report pressure-dependences of x-ray diffraction and photoluminescence from alkane-terminated colloidal particles. We determine the diamond-phase bulk modulus, observe multiple phase transitions, and importantly find a systematic photoluminescence red-shift that matches the Xconduction-to-valence transition of bulk ...
Liu Yihong - - 2012
Pinned water films in a microfluidic channel act as elastic membranes under tension that increase capillary pressures while preserving the mechanical work dissipated around capillary pressure-saturation, P(c)-S(w), hysteresis cycles. High-resolution two-photon laser micromachining of SU-8 photoresist was used to fabricate wedge-shaped microfluidic channels that included sharp edge features to pin ...
Senbel Amira M - - 2012
Objectives  This study aims to further elucidate the role of adrenergic transmission in erection and to highlight whether adrenergic transmission in the penis modulates sildenafil's action. Methods  measurement of intracavernosal pressure in the anesthetized rat model. Key findings  Guanethidine (3 and 6 mg/kg) potentiated intracavernosal pressure/mean arterial pressure (ICP/MAP) rises in ...
Kadhim Muayad - - 2012
Planovalgus foot deformity is common in children with cerebral palsy. Several pathologies contribute to the deformity. It begins with the lateral displacement of the navicular and the talar head becomes uncovered and prominent in the medial side of the midfoot. The purpose of this study was to assess the correlation ...
Eshet Hagai H Department of Chemistry and Applied Biosciences, ETH Zürich, Zürich, Switzerland. - - 2012
X-ray diffraction experiments have shown that sodium exhibits a dramatic pressure-induced drop in melting temperature, which extends from 1000 K at ~30 GPa to as low as room temperature at ~120 GPa. Despite significant theoretical effort to understand the anomalous melting, its origins are still debated. In this work, we ...
Ryan Silke - - 2011
Side-effects directly due to the nasal mask are common in patients with obstructive sleep apnoea syndrome (OSAS) commencing continuous positive airway pressure (CPAP). Recently, nasal pillows have been designed to overcome these issues. Limited evidence exists of the benefits and effectiveness of these devices. Twenty-one patients (19 male, 49±10years) with ...
Zampieri Fernando Godinho FG Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, - - 2011
To evaluate the effects of hemodynamic, respiratory and metabolic changes on intracranial pressure in a model of acute lung injury and abdominal compartment syndrome. Eight Agroceres pigs were submitted to five different clinical scenarios after instrumentation: 1) a baseline condition with low intra-abdominal pressure and healthy lungs; 2) pneumoperitoneum with ...
Goldberg David S - - 2011
56-year-old man who had previously undergone Jones tube placement began nasal continuous positive airway pressure for obstructive sleep apnea. Continuous positive airway pressure was not tolerated due to air regurgitation. A novel and simple treatment was devised by taping a small piece of wet cotton over the external end of ...
Weingarten Toby N - - 2011
BACKGROUND: The purpose of this study was to determine if the routine use of postoperative continuous positive airway pressure (CPAP) in patients undergoing laparoscopic Roux-en-Y gastric bypass (RYGB) is associated with an increase in transmural gastric pouch pressure, which may create the risk for anastomotic leak. METHODS: Transmural gastric pressures ...
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