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Paleczny Bartłomiej B Department of Physiology, Wroclaw Medical University, ul. Chałubińskiego 10, 50-368, Wroclaw, Poland, - - 2014
The study aimed: (i) to characterize reflex responses from peripheral and central chemoreceptors in different age groups of healthy men (<50 years old vs ≥50 years old) and, (ii) to assess, within these groups, whether there is any relationship between ventilatory and hemodynamic responses from chemoreceptors and indices of autonomic nervous system ...
Itagaki Taiga T Department of Emergency and Critical Care Medicine, University of Tokushima Graduate School, Tokushima, - - 2014
Excessive supplemental oxygen causes injurious hyperoxemia. Before establishing the best PaO2 targets for mechanically ventilated patients, it is important to understand the incidence of hyperoxemia and related factors. We investigated oxygenation in mechanically ventilated subjects in our ICU and evaluated factors related to hyperoxemia (PaO2 > 120 mm Hg) at ...
Jeffers Barrett W BW Pfizer Inc, New York, - - 2014
Small reductions in blood pressure reduce the risk of cardiovascular events. Here, we report 2 post hoc pooled analyses assessing the antihypertensive effect of amlodipine in patients who had not responded to 5 mg and were uptitrated to 10 mg. The first analysis assessed subgroups of patients aged either younger ...
Kushiro Toshio T The Life Planning Center Foundation, Tokyo, - - 2014
Few large-scale studies have evaluated the effectiveness of angiotensin receptor blockers in patients with masked hypertension (MH) and white coat hypertension (WCH) based on age using real-world blood pressure (BP) data. We used data from the Home BP measurement with Olmesartan Naive patients to Establish Standard Target BP (HONEST) study ...
Laborda Alicia A Alicia Laborda, Sergio Sierre, Ignatios Ioakeim, Miguel Angel De Gregorio, Minimally Invasive Techniques Research Group, Universidad de Zaragoza, 50013 Zaragoza, - - 2014
To study changes produced within the inferior vena cava (IVC) during respiratory movements and identify their possible clinical implications. This study included 100 patients (46 women; 54 men) over 18 years of age who required an abdominal computed tomography (CT) and central venous access. IVC cross-sectional areas were measured on ...
Ramirez-Correa Genaro Antonio GA Johns Hopkins School of - - 2014
Aims: Troponin I variant Pro82Ser (cTnIP82S) was initially considered a disease-causing mutation, however, later studies suggested the contrary. We tested the hypothesis of whether a causal link exists between cTnIP82S and cardiac structural and functional remodeling, such as during aging or chronic pressure-overload. Methods and results: A cardiac specific transgenic ...
Nongnuch Arkom A Renal Unit, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, - - 2014
Introduction: Increased natriuretic peptides are associated with increased cardiovascular and all-cause mortality for haemodialysis (HD) patients. However, debate continues whether these biomarkers are increased by extracellular water (ECW) excess and can be used to aid clinical assessment of volume status and help determine target weight. Methods: We measured N terminal ...
Lambeck Kurt K Research School of Earth Sciences, The Australian National University, Canberra, ACT 0200, Australia; Laboratoire de Géologie de l'École Normale Supérieure, UMR 8538 du CNRS, 75231 Paris, France; and - - 2014
The major cause of sea-level change during ice ages is the exchange of water between ice and ocean and the planet's dynamic response to the changing surface load. Inversion of ∼1,000 observations for the past 35,000 y from localities far from former ice margins has provided new constraints on the ...
Li Jian J Department of Clinical Laboratory, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guanzhou, Guangdong Province, People's Republic of - - 2014
Neutrophil to lymphocyte ratio (NLR) was reported to be an independent easy-to-measure marker for many diseases, while the distribution of NLR in healthy population was not formally studied. So we investigated NLR in healthy people in this study. Data include NLR, systolic pressure, diastolic pressure, and body mass index (BMI), ...
Nakhshab Maryam M Department of Pediatrics, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Mazandaran, Iran. Electronic address: - - 2014
Studies on early surfactant administration during nasal continuous positive airway pressure (NCPAP) [intubate-surfactant-extubate (INSURE)] have used continuous positive airway pressure and INSURE in the first hours after birth, but in many centers patients are transported from far away hospitals, reaching the center at a later time. The aim of this ...
Ghosh Arjun K AK International Centre for Circulatory Health, National Heart and Lung Institute, Imperial College London, 59-61 North Wharf Road, London W2 1LA, UK Medical Research Council Unit for Lifelong Health and Ageing, University College London, London, UK - - 2014
Antecedent blood pressure (BP) may contribute to cardiovascular disease (CVD) independent of current BP. Blood pressure is associated with left ventricular mass index (LVMI) which independently predicts CVD. We investigated the relationship between midlife BP from age 36 to 64 and LVMI at 60-64 years. A total of 1653 participants ...
Mikolajczak Stefanie S *University of Cologne, Department of Otorhinolaryngology, Head and Neck Surgery; †University of Cologne, Institute of Medical Statistics, Informatics and Epidemiology; and ‡Hospital "Schwarzwald-Baar Klinikum," Department of Otorhinolaryngology, Villingen-Schwenningen, - - 2014
Active and passive opening of the Eustachian tube (ET) enables direct aeration of the middle ear and a pressure balance between middle ear and the ambient pressure. The aim of this study was to characterize standard values for the opening pressure (ETOP), the opening frequency (ETOF), and the opening duration ...
Pessoa Isabela M B S IM Departamento de Fisioterapia, Pontifíca Universidade Católica de Minas Gerais, Belo Horizonte, MG, - - 2014
Background: The maximum static respiratory pressures, namely the maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP), reflect the strength of the respiratory muscles. These measures are simple, non-invasive, and have established diagnostic and prognostic value. This study is the first to examine the maximum respiratory pressures within the Brazilian ...
Pessoa Isabela M B S IM Departamento de Fisioterapia, Pontifíca Universidade Católica de Minas Gerais, Belo Horizonte, MG, - - 2014
The maximum static respiratory pressures, namely the maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP), reflect the strength of the respiratory muscles. These measures are simple, non-invasive, and have established diagnostic and prognostic value. This study is the first to examine the maximum respiratory pressures within the Brazilian population ...
Wang Jing-Zhi JZ Department of Automation, University of Science and Technology of China, Hefei, China; Research Center for Information Technology of Sports and Health, Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei, - - 2014
Augmentation index (AIx) and subendocardial viability ratio (SEVR) are widely accepted indices of wave reflection and myocardial oxygen demand relative to supply. This study aimed to validate a new tonometric device (IIM-2010A) for obtaining AIx and SEVR from radial artery. A total of 68 outpatients (32 men and 36 women) ...
Kharbanda Elyse Olshen EO HealthPartners Institute for Education and Research, Minneapolis, MN. Electronic address: - - 2014
To describe changes in systolic blood pressure (SBP), diastolic blood pressure (DBP), and body mass index (BMI) associated with initiation and continued use of combined oral contraceptives (COCs) in healthy adolescents. This observational, matched cohort study was conducted in 2 large health systems. Utilizing claims and electronic medical records, we ...
Besanko Laura K LK Investigation and Procedures Unit, Repatriation General Hospital,Australia. - - 2014
Swallowing difficulties become increasingly prevalent in older age. Differences exist in lower esophageal sphincter (LES) function between older and younger patients with dysphagia, but the contribution of aging per se to these is unclear. Esophageal motor function was measured using high resolution manometry in older (aged 81+/-1.7 yrs) and younger ...
Araki Toshimitsu T Department of Gastrointestinal and Pediatric Surgery, Division of Reparative Medicine, Institute of Life Sciences, Mie University Graduate School of Medicine, Mie, - - 2014
Aim: To retrospectively analyze manometric findings in patients with ulcerative colitis who underwent redo-ileo anal anastomosis for pouch-related complications. Methods: Functional and anal manometric parameters were analyzed before, immediately after, and 6 months after the procedure in 17 patients who underwent redo-ileo anal anastomosis between 2001 and 2012. Results: Of ...
Rosano Caterina C Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania; - - 2014
We sought to determine which systolic blood pressure (SBP) characteristics are associated with reduced brain integrity and whether these associations are stronger for white or gray matter. We hypothesized that exposure to higher and variable SBP will be associated with lower structural integrity of both gray and white matter. Neuroimaging, ...
Patrick James L JL Department of Radiology, University of Wisconsin School of Medicine & Public Health, E3/311 Clinical Science Center, 600 Highland Ave., Madison, WI, 53792-3252, - - 2014
To objectively compare colonic distention at CT colonography (CTC) achieved with manual room air vs. automated low-pressure carbon dioxide (CO2) using a novel automated volumetric quality assessment tool. Volumetric analysis was retrospectively performed on CTC studies in 300 asymptomatic adults using an automated quality assessment tool (V3D Colon [beta version], ...
El-Chammas Khalil I KI *Medical College of Wisconsin, Department of Pediatrics, Division of Pediatric Gastroenterology, Milwaukee, WI †Children's Hospital of Wisconsin, Children's Research Institute, Section of Quantitative Health Sciences, Milwaukee, - - 2014
Colon manometry is usually performed using 8-pressure sensor water perfused manometry system. High resolution manometry (HRM), using closely spaced solid state pressure recording sensors, provides more detailed information of gut luminal pressure changes, and by displaying the HRM data as pressure topographic plot (PTP), helps with data interpretation. Our aim ...
Lee Tae Hoon TH Internal Medicine, Soon Chun Hyang University College of Medicine, Cheonan Hospital, Cheonan, South - - 2014
Recent reports have indicated several instances of successful treatment of bowel perforation by using endoscopic band ligation (EBL) when treatment with endoclipping is unsuccessful, but this salvage method has not been investigated in any prospective model. Herein we aimed to compare the technical feasibility and efficacy of EBL and endoclip ...
Worametrachanon Srivilai S Division of Food Science and Technology, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai, 50100, - - 2014
The objective of the study was to examine the influence of encapsulated Lactobacillus casei 01 combining with two types of pressurized-purple-rice drinks on colonizing the colon using a simulator of the human intestinal microbial ecosystem. Subsequently, the metabolic products of colon bacteria and various microflora were determined. The finding revealed ...
Witmer Matthew T MT Retinal Consultants of Arizona, Phoenix, Ariz., - - 2014
The Alcon Constellation® provides state-of-the-art technology for vitrectomy surgery. Its innovative features include utilization of high-speed and small-gauge vitrectomy systems, surgeon-controlled duty cycle, fine intraocular pressure control, and integrated laser and intraocular gas mixing capabilities. The goal of vitrectomy surgery is the safe and efficient removal of vitreous while avoiding ...
Wise Erika K EK Department of Geography, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, - - 2014
Changes in moisture delivery to western North America are largely controlled by interrelated, synoptic-scale atmospheric pressure patterns. Long-term records of upper-atmosphere pressure and related circulation patterns are needed to assess potential drivers of past severe droughts and evaluate how future climate changes may impact hydroclimatic systems. Here we develop a ...
Ganade de Araujo Carlos E CE 1] Geological Survey of Brazil, Avenida Pasteur 404, CEP 22290-240, Rio de Janeiro, Brazil [2] Instituto de Geociências, Universidade de São Paulo, Rua do Lago, 562, CEP 05508-080, São Paulo, - - 2014
The deeply eroded West Gondwana Orogen is a major continental collision zone that exposes numerous occurrences of deeply subducted rocks, such as eclogites. The position of these eclogites marks the suture zone between colliding cratons, and the age of metamorphism constrains the transition from subduction-dominated tectonics to continental collision and ...
Lercher Peter P Division of Social Medicine, Medical University Innsbruck, Sonnenburgstrasse 16, A-6020 Innsbruck, Austria. - - 2014
Up to now, traffic noise effect studies focused on hypertension as health outcome. Hypotension has not been considered as a potential health outcome although in experiments some people also responded to noise with decreases of blood pressure. Currently, the characteristics of these persons are not known and whether this down ...
Vuorinen Miika M Department of Neurology, School of Medicine, University of Eastern Finland, Kuopio, - - 2014
Coronary heart disease (CHD) has been linked with cognitive decline and dementia in several studies. CHD is strongly associated with blood pressure, but it is not clear how blood pressure levels or changes in blood pressure over time affect the relation between CHD and dementia-related pathology. The aim of this ...
Woodford Darragh J DJ South African Institute for Aquatic Biodiversity, Grahamstown, South Africa. - - 2013
Propagule pressure is recognized as a fundamental driver of freshwater fish invasions, though few studies have quantified its role. Natural experiments can be used to quantify the role of this factor relative to others in driving establishment success. An irrigation network in South Africa takes water from an inter-basin water ...
Kim Young Hoon - - 2013
Conscious sedation of patients with midazolam reduces anxiety and pain and improves colonoscopy success rates. However, it may lead to adverse effects such as hypoxia and hypotension. The present study investigated the effects of midazolam on cardiopulmonary function during colonoscopy with conscious sedation. Between January 2011 and September 2011, 126 ...
Ji Chengdong - - 2013
Many studies have been conducted on colorectal anastomotic leakage to reduce the incidence of anastomotic leakage. However, how to precisely determine if the bowel can withstand the pressure of a colorectal anastomosis experiment, which is called anastomotic bursting pressure, has not been determined. A task force developed the experimental animal ...
Beck Christopher - - 2013
The aim of this study was to evaluate a newly developed infrared side-stream capnograph with minimal sample volume for the continuous measurement of end-tidal carbon dioxide (CO2) concentrations in small rodents. Thirty-four male Wistar rats (weight 345 ± 70 g) were treated in accordance with the National Institutes of Health (NIH) guidelines for ...
Kemik O - - 2013
Surgical interventions on left colon lead to high morbidity. The problems in wound healing are the main cause of this morbidity. Hypoxia retards wound healing and hyperbaric oxygen treatment (HBOT) has an anti-hypoxic effect. In this experimental study we divided eighty Wistar albino rats into eight groups and numbered between ...
Gurdal Sibel O - - 2013
Previous experimental studies have repeatedly demonstrated the potential protective effect of remote ischemic preconditioning (IPC) on colon anastomosis. The purpose of this experimental study was to investigate the possible positive effects of IPC by interval insufflations in laparoscopic colon operations. Thirty Wistar-albino rats were randomized into 3 groups. Colonic transsection ...
Durães Leonardo de Castro Lde - - 2013
To investigate the correlation between bursting pressure and breaking strength on the 7th postoperative day following left colonic anastomosis in rats. Seventy rats were randomly divided into seven groups of ten animals each. All of the animals underwent segmental resection of the left colon and end-to-end anastomosis. The animals in ...
Nemecek Elena - - 2013
BACKGROUND: Leakage is one of the major complications in gastrointestinal surgery. This preliminary study compared a new barbed absorbable thread for gastrointestinal sutures with monofil suture material in a cadaver model. METHODS: In this study, mechanical experiments were performed in 20 recently deceased individuals. Incisions were made in the small ...
Durães Leonardo de Castro Lde - - 2013
To evaluate the feasibility and safety of a new technique for laparoscopic segmental colectomy and primary anastomosis in the left colon of rats. Thirty rats were randomly assigned to three groups of ten animals each. All animals underwent segmental resection of the left colon and end-to-end anastomosis. In Group I, ...
Nessim Carolyn - - 2013
BACKGROUND: Despite the beneficial effects of epidurals in intra-abdominal surgery, the incidence of anastomotic leak remains controversial when used. Moreover, studies have also shown that fluid overload may be deleterious to anastomoses. The purpose of this paper is to evaluate the effects of varying intraoperative fluid protocols, in the presence ...
Corsetti M - - 2013
BACKGROUND: Alterations of nitrergic innervation have been implicated in the pathophysiology of motor-sensory abnormalities of post infectious functional dyspepsia and could be involved in the pathophysiology of post infectious irritable bowel syndrome. The role of nitrergic neurons in the control of distal colonic sensorimotor function in man is not known. ...
Linke Georg R - - 2013
PURPOSE: Although several studies have demonstrated the feasibility of transrectal natural orifice translumenal endoscopic surgery (NOTES), its clinical application has been hindered by concerns regarding potential infectious complications. The aim of this study was to evaluate the feasibility of a newly developed device for endolumenal colon occlusion (ColoShield) in an ...
Caglayan Kasim - - 2013
OBJECTIVES: The authors aimed to investigate the effect of β-Glucan on healing of an experimental left-sided colon anastomosis model. MATERIAL AND METHODS: Twenty adult male Wistar albino rats were randomized into two groups which had colonic transection and end-to-end anastomosis. Group I (Control): anastomosis group, received no treatment (n = ...
Bertrand Pierre-Marie - - 2013
Patient-ventilator asynchrony is common during noninvasive ventilation (NIV) with pressure support ventilation (PSV). We examined the effect of neurally adjusted ventilatory assist (NAVA) delivered through a facemask on synchronization in patients with acute respiratory failure (ARF). This was a prospective, physiologic, crossover study of 13 patients with ARF (median Pa(O(2))/F(IO(2)), ...
DalBen Mirian Freitas MF Faculdade de Medicina da Universidade de São Paulo, Department of Infectious Diseases and LIM 54, São Paulo/SPSP, - - 2013
To determine factors associated with colonization by carbapenem-resistant Pseudomonas aeruginosa and multiresistant Acinetobacter spp. Surveillance cultures were collected from patients admitted to the intensive care unit at admission, on the third day after admission and weekly until discharge. The outcome was colonization by these pathogens. Two interventions were implemented: education ...
Arkwright J W JW CSIRO Materials Science and Engineering, Lindfield, NSW, Australia. - - 2013
Manometry is commonly used for diagnosis of esophageal and anorectal motility disorders. In the colon, manometry is a useful tool, but clinical application remains uncertain. This uncertainty is partly based on the belief that manometry cannot reliably detect non-occluding colonic contractions and, therefore, cannot identify reliable markers of dysmotility. This ...
Roubinian Nareg - - 2012
Limited data are available on the effects of air travel in patients with pulmonary hypertension (PH), despite their risk of physiologic compromise. We sought to quantify the incidence and severity of hypoxemia experienced by people with PH during commercial air travel. We recruited 34 participants for a prospective observational study ...
Linge S O - - 2012
BACKGROUND AND PURPOSE:CSF fluid dynamics in healthy subjects and patients with Chiari I have been characterized during rest with phase-contrast MR imaging and CFD. CSF flow velocities and pressures in the nonresting state have not been adequately characterized. We used computer simulations to study CSF dynamics during increased heart rates ...
Abicht Jan-Michael - - 2012
Background: Displacement of the heart to expose the posterior vessels during off-pump coronary artery bypass (OPCAB) may cause hemodynamic instability. Deep pericardial traction suture (DPTS) and vacuum-assisted apical suction (VAS) with the Starfish positioning device help to provide good exposure without relevant hemodynamic changes. Our aim was to compare these ...
Navarro Lais Helena Camacho - - 2012
Early trauma care is dependent on subjective assessments and sporadic vital sign assessments. We hypothesized that near-infrared spectroscopy-measured cerebral oxygenation (regional oxygen saturation [rSO₂]) would provide a tool to detect cardiovascular compromise during active hemorrhage. We compared rSO₂ with invasively measured mixed venous oxygen saturation (SvO₂), mean arterial pressure (MAP), ...
Steinback Craig D - - 2012
Evidence suggests that the autonomic nervous system may actively regulate the cerebral vasculature. In this study, central hemodynamics and brain oxy-hemoglobin, deoxy-hemoglobin and total hemoglobin changes (bO(2)Hb, bdHb and bTHb) were monitored during infusion of epinephrine (0.06μg/kg/min over 6min, and 0.12μg/kg/min for 3min) in 12 men. Epinephrine decreased mean arterial ...
Ringer Simone K - - 2012
The objective of this study was to compare the cardiopulmonary effects of a xylazine or romifidine loading-dose, followed by a constant rate infusion (CRI) of the same α(2)-agonist. Nine research horses were treated in a randomized, blinded, crossover design with xylazine or romifidine. After instrumentation, a loading dose of intravenous ...
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