Search Results
Results 401 - 450 of 1621
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Cesarone Maria R - - 2008
This study investigated the efficacy of isotonic bioflavonoid supplementation, OPC-3 on 61 individuals presenting with risk factors meeting the criteria for metabolic syndrome. Subjects were supplemented with a proprietary isotonic bioflavonoid OPC-3 or placebo over 2 months. Plasma oxidative stress status was significantly lowered by 10.1% with OPC-3. All major ...
Abe Toshikazu - - 2008
Previous studies have suggested a possible association between meteorological factors and the onset of subarachnoid hemorrhage (SAH). We aimed to investigate the relationship between the onset of SAH and meteorological factors based on an hourly time-series analysis. We collected hourly data on transportation of patients with SAH using the ambulance ...
Gasowski Jerzy J Department of Internal Medicine and Gerontology, Jagiellonian University, Kraków, - - 2008
The 24-h ambulatory blood pressure (ABP) is a stronger predictor of cardiovascular disease than conventional blood pressure (CBP), but it remains unclear how it compares with "usual" blood pressure (UBP), estimated after CBP has been corrected for regression dilution bias (RDB). We compared the associations of cardiovascular mortality (n = ...
Ilva Tuomo - - 2008
Elevated cardiac troponin (cTn) levels are relatively common in acute heart failure (AHF). To evaluate the prevalence and prognostic significance of elevated cTnI and cTnT in AHF. FINN-AKVA is a prospective, multicenter study in AHF. In this analysis, 364 non-ACS patients with measurements of cTnI and cTnT taken on admission ...
Ormezzano Olivier - - 2008
AIMS: The prognostic value of baroreflex sensitivity in hypertensive patients has not much been studied. METHOD: A cohort of 451 hypertensive patients without cardiovascular history was studied for an average of 6.2 +/- 2.8 years follow-up. Each patient had a baroreflex sensitivity measurement by the sequence method, which is represented ...
Conen David - - 2008
OBJECTIVE: We systematically assessed the evidence regarding the association between noninvasive 24-h systolic blood pressure and incident cardiovascular events. METHODS: We searched PubMed, EMBASE, and the Cochrane Library through April 2007. Studies that prospectively followed at least 100 individuals for at least 1 year, and that reported at least one ...
Eftimovska N - - 2008
INTRODUCTION: The risk factors for CKD include diabetes, hypertension, smoking, systemic inflammation, obesity, proteinuria, dislipidaemia and anaemia, as well as gender, age, ethnic minority status and positive family history. By screening and adequate treatment of modifiable risk factors we are able to prevent or delay the progression of the disease. ...
Huang Pinchia P Division of Biostatistics, Washington University School of Medicine, Saint Louis, MO 63110, - - 2008
Metabolic syndrome and its risk factors are predictors of cardiovascular events. Metabolic syndrome is also directly associated with echocardiographic phenotypes. The current study is the first to investigate the factors associated with both metabolic syndrome risk factors and echocardiographic phenotypes and assess their heritability. Multivariate factor analysis was performed on ...
Chalmers John - - 2008
OBJECTIVES: ADVANCE was planned to investigate the effects of routine blood pressure lowering with the fixed combination perindopril-indapamide on major vascular events in people with type 2 diabetes, irrespective of initial blood pressures or the use of other blood pressure-lowering drugs, including angiotensin-converting enzyme inhibitors. METHODS: A total of 11 ...
Viitasalo Katriina - - 2008
OBJECTIVES: A controlled intervention study was conducted to evaluate the effects of two changes in shift characteristics on alertness and cardiovascular risk factors: a change in shift rotation (direction and speed) and a change in the flexibility of the shift system. METHODS: Altogether 84 male workers currently working in a ...
Thomas Frédérique - - 2008
OBJECTIVES: This study determines the predictive value of brachial pulse pressure for cardiovascular stroke and coronary mortality in a large population categorized by blood pressure level. METHODS: The population was composed of 69,989 subjects aged more than 50 years and divided into 'optimal', 'normal' and 'normal high' normotensive subjects, and ...
Ohkubo Takayoshi - - 2008
The prognostic significance of morning surge in blood pressure (BP) remains obscure because the findings of the four prospective studies available [ambulatory BP monitoring (ABPM) substudy of the Syst-Eur trial, the Jichii Medical School ABPM-wave1 study, the Bordeaux hypertensive cohort study, and the Ohasama study] have generated conflicting results partly ...
Pannier Bruno - - 2008
OBJECTIVES: Few data are available on the impact of the metabolic syndrome on all-cause mortality risk according to the presence of hypertension. Our aim was to evaluate the 5-year impact of the metabolic syndrome, according to blood pressure status, on all-cause mortality risk in a large French population. METHODS: The ...
Li Jiajin - - 2008
OBJECTIVE: The objective of this study was to assess the prevalence and correlative risk factors of isolated untreated systolic hypertension and other hypertension subtypes among Mongolians and Han rural adults of China. METHODS AND RESULTS: The study was conducted in 2004-2006 and used a multistage cluster sampling method to select ...
Nilsson Peter M - - 2008
Early vascular ageing is common in patients with hypertension and increased burden of cardiovascular risk factors, often influenced by chronic inflammation. One aspect of this vascular ageing is arterial stiffening, as measured by increased pulse wave velocity or augmentation index and central pressure. Several studies have indicated that this process ...
Padwal Raj S - - 2008
To provide updated, evidence-based recommendations for the diagnosis and assessment of adults with hypertension. The diagnosis of hypertension is dependent on appropriate blood pressure measurement, the timely assessment of serially elevated readings, degree of blood pressure elevation, method of measurement (office, ambulatory, home) and associated comorbidities. The presence of cardiovascular ...
Wang Jie Jin - - 2008
The authors assessed associations between retinal vascular signs and incident severe hypertension in an older population-based cohort. At baseline (1992-1994), 3,654 residents aged 49-97 years living in the Blue Mountains area west of Sydney, Australia, were examined; respectively, 2,335 (75.1%) and 1,952 (76%) survivors were reexamined 5 and 10 years ...
Panoulas V F - - 2008
RA associates with an increased burden of cardiovascular disease, which is at least partially attributed to classical risk factors such as hypertension (HT) and dyslipidaemia. HT is highly prevalent, and seems to be under-diagnosed and under-treated among patients with RA. In this review, we discuss the mechanisms that may lead ...
Shah Sanjiv J - - 2008
BACKGROUND: Renal dysfunction predicts mortality in patients with cardiovascular disease. How renal dysfunction relates to hemodynamics and mortality in pulmonary arterial hypertension (PAH) remains unclear. METHODS AND RESULTS: We performed a cohort study of 500 patients with World Health Organization group I PAH from 1982 to 2006 with data on ...
Lawes Carlene M M - - 2008
BACKGROUND: Few studies have assessed the extent and distribution of the blood-pressure burden worldwide. The aim of this study was to quantify the global burden of disease related to high blood pressure. METHODS: Worldwide burden of disease attributable to high blood pressure (> or =115 mm Hg systolic) was estimated ...
Martini Ligia A - - 2008
Hypertension is an important risk factor for cardiovascular and kidney disease. High blood pressure is a growing public health problem that is expected to affect 1.6 billion people worldwide by the year 2025. In light of emerging evidence of a widespread global problem of vitamin D deficiency, there has been ...
Zaiem Ahmed - - 2008
Perindopril, a prodrug ester of perindoprilat, is an angiotensin-converting enzyme inhibitor that lowers angiotensin II and potentiates bradykinin. This agent has proven efficacy in a wide range of cardiovascular diseases. Its efficacy, safety and tolerability are well established in the treatment of hypertension. Beyond pharmacodynamic effects shown in lowering blood ...
Navas-Acien Ana - - 2008
BACKGROUND: Previous reviews have shown increases in blood pressure and hypertension associated with increases in lead levels in blood. We performed a meta-analysis of the association of bone lead levels with systolic blood pressure, diastolic blood pressure, and hypertension using published data. METHODS: We searched Medline, Embase, and Toxline for ...
Viazzi Francesca - - 2008
Sub-clinical organ damage is a strong independent predictor of cardiovascular mortality in primary hypertension, and its changes over time parallel those in risk of cardiovascular events. A better understanding of the pathogenetic mechanisms underlying the development of target organ damage may help us devise more effective therapeutic strategies. We therefore ...
Ayo-Yusuf Olalekan A OA Department of Community Dentistry, School of Dentistry, University of Pretoria. - - 2008
Hypertension may result from changes in dietary quality and nutrient intake. We therefore sought to determine the epidemiological association between tooth loss and hypertension in South African adults. This is a secondary data analysis of a cross-sectional survey of a nationally representative sample of adults aged 25 - 70 years ...
Murakami Yoshitaka - - 2008
Hypertension is a leading cause of death because of cardiovascular disease and predominantly affects total mortality. To reduce avoidable deaths from hypertension, we need to collect blood pressure data and assess their impact on total mortality. To examine this issue, a meta-analysis of 13 cohort studies was conducted in Japan. ...
Ang Dsc - - 2008
In hypertension, the presence of left ventricular hypertrophy (LVH) is associated with increased risk of both cardiovascular morbidity and mortality. To date, the electrocardiogram (ECG) remains the cornerstone of LVH diagnosis in clinical practice because it is universally available, technically easy to perform and highly specific. In the most recent ...
Holmes Elaine - - 2008
Metabolic phenotypes are the products of interactions among a variety of factors-dietary, other lifestyle/environmental, gut microbial and genetic. We use a large-scale exploratory analytical approach to investigate metabolic phenotype variation across and within four human populations, based on 1H NMR spectroscopy. Metabolites discriminating across populations are then linked to data ...
Hergens M-P - - 2008
BACKGROUND: The scientific evidence on whether long-term use of snuff is associated with high blood pressure is limited, inconsistent and based only on cross-sectional data. OBJECTIVE: We aimed at studying the risk of hypertension in relation to long-term use of snuff based on longitudinal data. DESIGN: Repeated health check-ups were ...
Singer D R J - - 2008
Cardiovascular disease and death are major life-threatening problems in patients with atheromatous peripheral arterial disease (PAD). This review focuses on management of hypertension in the context of cardiovascular risk in patients with PAD. PAD is underdiagnosed and hypertension in PAD is often poorly managed. Current evidence supports a low threshold ...
Chalmers John - - 2008
1. The epidemic of diabetes is accelerating and the World Health Organization estimates that the number of people affected worldwide will grow from 171 million in 2000 to 366 million by 2030. 2. The main causes of death and disability in individuals with type 2 diabetes are macrovascular and microvascular ...
Wen Chi Pang - - 2008
OBJECTIVE: To express the increased risk from smoking in terms of 'blood pressure' so that hypertensive smokers are motivated into quitting. METHODS: Mortality risks of smokers were compared with nonsmokers in a large worker cohort in Taiwan (n = 23755 with a 17-year follow-up) for all-cause and for cardiovascular diseases. ...
Spence Vance A - - 2008
Some of the symptoms reported by people with CFS (chronic fatigue syndrome) are associated with various cardiovascular phenomena. Markers of cardiovascular risk, including inflammation and oxidative stress, have been demonstrated in some patients with CFS, but little is known about the relationship between these and prognostic indicators of cardiovascular risk ...
Head Geoffrey A - - 2008
1. The morning period has been recognized as the highest risk period of the day for cardiovascular events, particularly stroke and is also associated with a rapid surge in blood pressure. 2. Evidence now exists to show that the morning surge in blood pressure is an independent risk factor in ...
Iwashima Yoshio - - 2008
OBJECTIVE: The prognostic significance of the pulmonary venous flow in essential hypertensive patients was investigated. METHODS AND RESULTS: Doppler transthoracic echocardiograms were analyzed in 705 essential hypertensive subjects with no prior cardiovascular disease. At baseline, most subjects had 'normal diastolic function' or 'mild diastolic dysfunction'. During follow-up (mean, 32 months), ...
Vlcek Marianne - - 2008
OBJECTIVE: To determine whether patients with hypertensive urgency have a higher risk for subsequent cardiovascular events compared with hypertensive patients without this event. METHODS: Overall, 384 patients with hypertensive urgency and 295 control patients were followed up for at least 2 years. Hypertensive urgency was defined as a systolic blood ...
Pavlopoulos Harry - - 2008
Hypertension should be regarded not as a simple elevation of blood pressure, but as a constellation of functional and structural abnormalities that create a phenotypic portrait of hypertensive disease. Recent research has expanded our knowledge related to hypertensive heart disease. Future assessment of hypertensive patients' global risk should probably incorporate ...
Christensen Cynthia - - 2008
Panama is a beautiful country with many disparities. It was estimated in 1995 that 40% of the population lived in poverty. Deaths from cardiovascular disease increased by 2% annually from 1990 to 1994, with hypertension being the leading cause of death for persons aged 60 years or more. I had ...
Henry R M A - - 2008
BACKGROUND: Type 2 diabetes (DM2) is associated with a greater risk of heart failure. The mechanisms underlying this association remain controversial and include diabetes-associated hypertension and obesity, impaired small and large artery function, and a distinct metabolic cardiomyopathy related to hyperglycaemia/ hyperinsulinaemia. The proximate causes of heart failure are left ...
Brooks Deborah - - 2008
The African American Study of Kidney Disease and Hypertension (AASK) was conducted over a 7-year period at 21 clinical centers across the United States to investigate whether one of two levels of blood pressure control and/or one of three classes of antihypertensive medications was more effective at slowing the rate ...
Firdaus Muhammad - - 2008
Hypertension in older adults is not well controlled in clinical practice. Isolated systolic hypertension is often more difficult to manage. A systematic PubMed search was conducted to look for evidence showing benefits of lowering blood pressure (BP) in older hypertensive adults. Lowering BP in these individuals significantly reduces the risk ...
Rao Anupama K AK Division of Cardiovascular Medicine and Section of Nephrology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, - - 2008
Left atrial volume (LAV) is an independent echocardiographic predictor of cardiovascular events in the general population. We evaluated predictors of LAV in patients with advanced chronic kidney disease (CKD). Increasing LAV identifies increased cardiovascular risk in patients with CKD. Transthoracic echocardiography was performed in CKD patients undergoing cardiovascular evaluation prior ...
Naschitz J E - - 2008
BACKGROUND: Post-traumatic lower limb amputees have an increased morbidity and mortality from cardiovascular disease. Risk factors for this amplified morbidity and the involved pathophysiologic mechanisms have not been comprehensively studied. METHODS: The MEDLINE database was reviewed, with case-controlled studies and nested in cohort studies eligible for inclusion in this analysis. ...
Hansen T - - 2008
The aim of this study was to create a scoring system for whole-body magnetic resonance angiography (WBMRA) that allows estimation of atherosclerotic induced luminal narrowing, and determine whether the traditional cardiovascular (CV) risk factors included in the Framingham risk score (FRS) were related to this total atherosclerotic score (TAS) in ...
Gu Qiuping - - 2008
PURPOSE: We sought to examine whether prehypertension is associated with increased cardiovascular disease (CVD) mortality risk and whether the association of blood pressure with CVD outcome is modified by social demographics or hypertension treatment and control. METHODS: Data from the Third National Health and Nutrition Examination Survey and mortality follow-up ...
Sutton-Tyrrell Kim - - 2008
BACKGROUND AND PURPOSE: Low values of ankle-arm systolic blood pressure ratio predict mortality and cardiovascular events. High values, associated with arterial calcification, also carry risk for mortality. We focus on the extent to which low and high ankle-arm index values as well as noncompressible arteries are associated with mortality and ...
Nakagawa Naoki - - 2008
Chronic kidney disease (CKD) is associated with an increased risk of cardiovascular disease, and thus is a major worldwide public health problem. Recently, an estimated glomerular filtration rate (eGFR) using the Modification of Diet in Renal Disease equation for Japanese patients was proposed by the Japanese Society of Nephrology. However, ...
Marant C - - 2008
AIMS: In type 2 diabetes (T2D), to describe treatments to prevent cardiovascular disease, to compare current practice to French guidelines, and to identify factors associated with recommended treatments. METHODS: In the Echantillon National Témoin Représentatif des Personnes Diabétiques (ENTRED) study, 10,000 adults treated for diabetes (any type) were randomly selected ...
Patel Priyesh V - - 2008
Adverse cardiovascular events such as myocardial infarction, stroke, arrhythmias, and sudden cardiac death are well known to follow a circadian pattern, peaking in the morning hours of 6 AM to 12 PM. Many physiologic factors have been shown to follow a circadian pattern and together may create an environment that ...
Kagiyama Shuntaro - - 2008
Hypertension is one of the greatest risk factors for cardiovascular disease, but the contribution of high blood pressure to cardiovascular morbidity and mortality is weakened with aging. In the present study, we examined whether high blood pressure would be a risk factor for total and cardiovascular mortality in a group ...
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