Search Results
Results 351 - 400 of 1595
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Paglieri Cristina - - 2008
Arterial hypertension, cerebrovascular disease, and dementia are related pathologies. This paper has reviewed comparatively the incidence of arterial hypertension and adult-onset dementia disorders. Hypertension is associated with cerebrovascular disease, which is in turn associated with dementia. It is the most important modifiable risk factor for stroke, which is a recognized ...
Mogensen Carl Erik - - 2008
In the last 30 years we have seen considerable progress in the management of patients with diabetes, in particular with diabetic renal disease. A number of paradigms have been broken down, namely the following, as a consequence, clinical care has improved dramatically. . Significant renal involvement and albuminuria is rare ...
Windak Adam - - 2009
OBJECTIVE: The aim of this study was to assess the advice about lifestyle changes that general practitioners (GPs) gave hypertensive patients with different levels of cardiovascular risk. DESIGN: and METHODS: A stratified sample of primary health care physicians in Poland completed a questionnaire consisting of 8 case vignettes that differed ...
Kales Stefanos N - - 2009
Elevated blood pressure is a major risk factor for cardiovascular morbidity and mortality. Increased risk begins in the prehypertensive range and increases further with higher pressures. The strenuous duties of emergency responders (firefighters, police officers, and emergency medical services (EMS) personnel) can interact with their personal risk profiles, including elevated ...
Minor Deborah - - 2008
Hypertension is a major cause of disease burden in all racial, ethnic, and socioeconomic groups in developing and developed regions and countries. Differences in blood pressure likely begin early in life and reflect a complex relationship of biologic, genetic, social, and environmental interactions. The relationship between socioeconomic status and hypertension ...
Egan Brent M - - 2008
Approximately 37% of US adults are prehypertensive; about 31 million have blood pressures in the range of 130-139/85-89 mm Hg. These stage 2 prehypertensives have threefold greater risk for developing hypertension and twofold higher risk for cardiovascular events than normotensives. Lifestyle changes only are recommended for most prehypertensives, but evidence ...
Holman Rury R - - 2008
BACKGROUND: Post-trial monitoring of patients in the United Kingdom Prospective Diabetes Study (UKPDS) examined whether risk reductions for microvascular and macrovascular disease, achieved with the use of improved blood-pressure control during the trial, would be sustained. METHODS: Among 5102 UKPDS patients with newly diagnosed type 2 diabetes mellitus, we randomly ...
Mitchell Gary F - - 2008
Over the past decade, numerous studies have shown that increased aortic stiffness is associated with major cardiovascular disease end points, including heart disease, stroke, and kidney disease. Cardiac abnormalities and enhanced atherogenesis in the setting of increased pulsatile load on heart and arteries have been well described. However, recent studies ...
Bass Cameron R - - 2008
BACKGROUND: Blast injuries are becoming more common in modern war and terrorist action. This increasing threat underscores the importance of understanding and evaluating blast effects. METHODS: For this study, data on more than 2,550 large animal experiments were collected from more than 50 experimental studies on blast. From this dataset, ...
Vlachopoulos Charalambos - - 2008
OBJECTIVE: Erectile dysfunction is a predictor of cardiovascular risk with high prevalence in hypertensive men. We investigated whether erectile dysfunction is related to arterial structure and function in hypertensive patients. METHODS: We evaluated arterial structural and functional characteristics and measured systemic endothelial/inflammatory markers in 52 hypertensive men with vasculogenic erectile ...
Guize Louis - - 2008
Metabolic syndrome is defined as an association of central obesity and several other cardiometabolic risk factors. Dysfunctional visceral adipose tissue and inflammatory status appear to be involved in its genesis. New definitions have decreased the threshold for glycaemia and one has lowered the threshold for waist circumference, leading to an ...
Ishimitsu Toshihiko - - 2008
We conducted a prospective study investigating the relationship between blood pressure values and the risk of cardiovascular disease in patients with end-stage renal diseases. Five hundred fifty-three patients on chronic hemodialysis were followed for 5 years, and the relationship between systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood ...
Papadopoulos Dimitris P - - 2008
Prehypertension, defined as blood pressure between 120-139/80-89 mmHg, is a major public health concern. The condition is very prevalent (30% of the adult population), is often associated with other cardiovascular risk factors and independently increases the risk of hypertension and subsequent cardiovascular events. The mechanism of elevated risk for cardiovascular ...
Katakam Radhika - - 2008
Because hypertension is common and many tests are available, an uncritical approach to laboratory and radiologic evaluation leads to unnecessary expenses. However, in most patients, accurate blood pressure measurement, a focused history and physical examination, and a handful of basic tests are enough. In this review we address the key ...
Brunelli Steven M - - 2008
BACKGROUND: Blood pressure variability (BPV) is one putative risk factor for cardiovascular disease and mortality in hemodialysis patients. The purposes of this study are to identify a suitable metric of long-term BPV in this population and determine whether an association between BPV and all-cause mortality exists. STUDY DESIGN: Retrospective cohort ...
Simkhovich Boris Z - - 2008
Recent epidemiologic studies show that increased levels of air pollutants are positively associated with cardiovascular morbidity and mortality. Inhalation of air pollutants affects heart rate, heart rate variability, blood pressure, vascular tone, blood coagulability, and the progression of atherosclerosis. Several categories within the general population (i.e., people with pre-existing cardiovascular ...
Kokubo Yoshihiro - - 2008
Few prospective studies have examined the association between high-normal blood pressure and cardiovascular disease (CVD) in Asia. We examined the impact of high-normal blood pressure on the incidence of CVD in a general urban population cohort in Japan. We studied 5494 Japanese individuals (ages 30 to 79 years without CVD ...
Scheffler A - - 2008
ETHNOPHARMACOLOGICAL RELEVANCE: In Southern Europe Olea europaea leafs are known as a folk remedy for hypertension. Cardiovascular diseases are still the leading causes of morbidity and mortality in industrialized countries with hypertension being one of the main risk factors. AIM OF THE STUDY: We investigated effects of a commercial Olea ...
Espinola-Klein Christine - - 2008
BACKGROUND: An ankle-brachial index (ABI; ratio of ankle and brachial systolic blood pressure) <0.9 indicates peripheral arterial disease (PAD) and is a strong predictor of cardiovascular events. The aim of the present study was to address the prognostic value of different methods of ABI calculation. METHODS AND RESULTS: In 831 ...
Kobayashi Mayumi - - 2009
The presence of silent brain infarction (SBI) increases the risk of symptomatic stroke and dementia. The association between SBI and chronic kidney disease (CKD) has not been clarified. Moreover, little is known about what factors are related to SBI in CKD patients and whether the prevalence of SBI differs in ...
Roland M - - 2008
Risk factors for new-onset diabetes after transplantation (NODAT) need to be assessed in large cohorts. We retrospectively evaluated the impact of early (3 and 6 months after transplantation) proteinuria, urinary albumin excretion (UAE) and arterial pressure on NODAT in 828 Caucasian renal transplant recipients (median follow-up: 5.3 years; 5832 patient-years). ...
Humphrey Robert - - 2008
OBJECTIVE: We conducted a retrospective cohort study to determine whether laparoscopic adrenalectomy (LA) is a safe and effective therapy for the management of pheochromocytoma, as compared with open adrenalectomy (OA). METHODS: We collected pertinent data on 47 pheochromocytoma resections from 44 patient charts. Perioperative outcomes of 30 LAs were compared ...
Gus M - - 2009
BACKGROUND AND AIMS: Central obesity is a key component in the definition of the metabolic syndrome, but the cut-off values proposed to define abnormal values vary among different guidelines and are mostly based on cross-sectional studies. In this study, we identify the best cut-off values for waist circumference (WC) associated ...
Raphael C E - - 2009
BACKGROUND: Although higher blood pressures are generally recognised to be an adverse prognostic marker in risk assessment of cardiology patients, its relationship to risk in chronic heart failure (CHF) may be different. OBJECTIVE: To examine systematically published reports on the relationship between blood pressure and mortality in CHF. METHODS: Medline ...
Cesarone Maria R - - 2008
This study investigated the efficacy of isotonic bioflavonoid supplementation, OPC-3 on 61 individuals presenting with risk factors meeting the criteria for metabolic syndrome. Subjects were supplemented with a proprietary isotonic bioflavonoid OPC-3 or placebo over 2 months. Plasma oxidative stress status was significantly lowered by 10.1% with OPC-3. All major ...
Abe Toshikazu - - 2008
Previous studies have suggested a possible association between meteorological factors and the onset of subarachnoid hemorrhage (SAH). We aimed to investigate the relationship between the onset of SAH and meteorological factors based on an hourly time-series analysis. We collected hourly data on transportation of patients with SAH using the ambulance ...
Gasowski Jerzy - - 2008
BACKGROUND: The 24-h ambulatory blood pressure (ABP) is a stronger predictor of cardiovascular disease than conventional blood pressure (CBP), but it remains unclear how it compares with "usual" blood pressure (UBP), estimated after CBP has been corrected for regression dilution bias (RDB). METHODS: We compared the associations of cardiovascular mortality ...
Ilva Tuomo - - 2008
Elevated cardiac troponin (cTn) levels are relatively common in acute heart failure (AHF). To evaluate the prevalence and prognostic significance of elevated cTnI and cTnT in AHF. FINN-AKVA is a prospective, multicenter study in AHF. In this analysis, 364 non-ACS patients with measurements of cTnI and cTnT taken on admission ...
Ormezzano Olivier - - 2008
AIMS: The prognostic value of baroreflex sensitivity in hypertensive patients has not much been studied. METHOD: A cohort of 451 hypertensive patients without cardiovascular history was studied for an average of 6.2 +/- 2.8 years follow-up. Each patient had a baroreflex sensitivity measurement by the sequence method, which is represented ...
Conen David - - 2008
OBJECTIVE: We systematically assessed the evidence regarding the association between noninvasive 24-h systolic blood pressure and incident cardiovascular events. METHODS: We searched PubMed, EMBASE, and the Cochrane Library through April 2007. Studies that prospectively followed at least 100 individuals for at least 1 year, and that reported at least one ...
Eftimovska N - - 2008
INTRODUCTION: The risk factors for CKD include diabetes, hypertension, smoking, systemic inflammation, obesity, proteinuria, dislipidaemia and anaemia, as well as gender, age, ethnic minority status and positive family history. By screening and adequate treatment of modifiable risk factors we are able to prevent or delay the progression of the disease. ...
Huang Pinchia - - 2008
Metabolic syndrome and its risk factors are predictors of cardiovascular events. Metabolic syndrome is also directly associated with echocardiographic phenotypes. The current study is the first to investigate the factors associated with both metabolic syndrome risk factors and echocardiographic phenotypes and assess their heritability. Multivariate factor analysis was performed on ...
Chalmers John - - 2008
OBJECTIVES: ADVANCE was planned to investigate the effects of routine blood pressure lowering with the fixed combination perindopril-indapamide on major vascular events in people with type 2 diabetes, irrespective of initial blood pressures or the use of other blood pressure-lowering drugs, including angiotensin-converting enzyme inhibitors. METHODS: A total of 11 ...
Viitasalo Katriina - - 2008
OBJECTIVES: A controlled intervention study was conducted to evaluate the effects of two changes in shift characteristics on alertness and cardiovascular risk factors: a change in shift rotation (direction and speed) and a change in the flexibility of the shift system. METHODS: Altogether 84 male workers currently working in a ...
Thomas Frédérique - - 2008
OBJECTIVES: This study determines the predictive value of brachial pulse pressure for cardiovascular stroke and coronary mortality in a large population categorized by blood pressure level. METHODS: The population was composed of 69,989 subjects aged more than 50 years and divided into 'optimal', 'normal' and 'normal high' normotensive subjects, and ...
Ohkubo Takayoshi - - 2008
The prognostic significance of morning surge in blood pressure (BP) remains obscure because the findings of the four prospective studies available [ambulatory BP monitoring (ABPM) substudy of the Syst-Eur trial, the Jichii Medical School ABPM-wave1 study, the Bordeaux hypertensive cohort study, and the Ohasama study] have generated conflicting results partly ...
Pannier Bruno - - 2008
OBJECTIVES: Few data are available on the impact of the metabolic syndrome on all-cause mortality risk according to the presence of hypertension. Our aim was to evaluate the 5-year impact of the metabolic syndrome, according to blood pressure status, on all-cause mortality risk in a large French population. METHODS: The ...
Li Jiajin - - 2008
OBJECTIVE: The objective of this study was to assess the prevalence and correlative risk factors of isolated untreated systolic hypertension and other hypertension subtypes among Mongolians and Han rural adults of China. METHODS AND RESULTS: The study was conducted in 2004-2006 and used a multistage cluster sampling method to select ...
Nilsson Peter M - - 2008
Early vascular ageing is common in patients with hypertension and increased burden of cardiovascular risk factors, often influenced by chronic inflammation. One aspect of this vascular ageing is arterial stiffening, as measured by increased pulse wave velocity or augmentation index and central pressure. Several studies have indicated that this process ...
Padwal Raj S - - 2008
To provide updated, evidence-based recommendations for the diagnosis and assessment of adults with hypertension. The diagnosis of hypertension is dependent on appropriate blood pressure measurement, the timely assessment of serially elevated readings, degree of blood pressure elevation, method of measurement (office, ambulatory, home) and associated comorbidities. The presence of cardiovascular ...
Wang Jie Jin - - 2008
The authors assessed associations between retinal vascular signs and incident severe hypertension in an older population-based cohort. At baseline (1992-1994), 3,654 residents aged 49-97 years living in the Blue Mountains area west of Sydney, Australia, were examined; respectively, 2,335 (75.1%) and 1,952 (76%) survivors were reexamined 5 and 10 years ...
Panoulas V F - - 2008
RA associates with an increased burden of cardiovascular disease, which is at least partially attributed to classical risk factors such as hypertension (HT) and dyslipidaemia. HT is highly prevalent, and seems to be under-diagnosed and under-treated among patients with RA. In this review, we discuss the mechanisms that may lead ...
Shah Sanjiv J - - 2008
BACKGROUND: Renal dysfunction predicts mortality in patients with cardiovascular disease. How renal dysfunction relates to hemodynamics and mortality in pulmonary arterial hypertension (PAH) remains unclear. METHODS AND RESULTS: We performed a cohort study of 500 patients with World Health Organization group I PAH from 1982 to 2006 with data on ...
Lawes Carlene M M - - 2008
BACKGROUND: Few studies have assessed the extent and distribution of the blood-pressure burden worldwide. The aim of this study was to quantify the global burden of disease related to high blood pressure. METHODS: Worldwide burden of disease attributable to high blood pressure (> or =115 mm Hg systolic) was estimated ...
Martini Ligia A - - 2008
Hypertension is an important risk factor for cardiovascular and kidney disease. High blood pressure is a growing public health problem that is expected to affect 1.6 billion people worldwide by the year 2025. In light of emerging evidence of a widespread global problem of vitamin D deficiency, there has been ...
Zaiem Ahmed - - 2008
Perindopril, a prodrug ester of perindoprilat, is an angiotensin-converting enzyme inhibitor that lowers angiotensin II and potentiates bradykinin. This agent has proven efficacy in a wide range of cardiovascular diseases. Its efficacy, safety and tolerability are well established in the treatment of hypertension. Beyond pharmacodynamic effects shown in lowering blood ...
Navas-Acien Ana - - 2008
BACKGROUND: Previous reviews have shown increases in blood pressure and hypertension associated with increases in lead levels in blood. We performed a meta-analysis of the association of bone lead levels with systolic blood pressure, diastolic blood pressure, and hypertension using published data. METHODS: We searched Medline, Embase, and Toxline for ...
Viazzi Francesca - - 2008
Sub-clinical organ damage is a strong independent predictor of cardiovascular mortality in primary hypertension, and its changes over time parallel those in risk of cardiovascular events. A better understanding of the pathogenetic mechanisms underlying the development of target organ damage may help us devise more effective therapeutic strategies. We therefore ...
Ayo-Yusuf Olalekan A OA Department of Community Dentistry, School of Dentistry, University of Pretoria. - - 2008
Hypertension may result from changes in dietary quality and nutrient intake. We therefore sought to determine the epidemiological association between tooth loss and hypertension in South African adults. This is a secondary data analysis of a cross-sectional survey of a nationally representative sample of adults aged 25 - 70 years ...
Murakami Yoshitaka - - 2008
Hypertension is a leading cause of death because of cardiovascular disease and predominantly affects total mortality. To reduce avoidable deaths from hypertension, we need to collect blood pressure data and assess their impact on total mortality. To examine this issue, a meta-analysis of 13 cohort studies was conducted in Japan. ...
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