Search Results
Results 301 - 350 of 1599
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Cuspidi Cesare - - 2009
The clinical value of left ventricular hypertrophy (LVH), a cardinal manifestation of hypertensive organ damage, in predicting cardiovascular (CV) events, independently of blood pressure (BP) and other accompanying risk factors, has been widely documented and its role in CV stratification indisputability recognized. Although the examination of the fundus oculi provides ...
Lam Carolyn S P - - 2009
In contrast to the wealth of data on isolated systolic hypertension involving the systemic circulation in the elderly, much less is known about age-related change in pulmonary artery systolic pressure (PASP) and its prognostic impact in the general population. We sought to define the relationship between PASP and age, to ...
Ruilope Luis M - - 2009
The need to prevent the development of renal damage and its associated increase in cardiovascular risk in patients with type 2 diabetes is well established. Early intervention to maintain strict blood pressure control and to prevent the development of microalbuminuria is mandatory and will constitute the primary aim of intervention ...
Safar Michel E - - 2009
This article discusses the following: (1) factors modulating central and peripheral SBP and PP in hypertensive subjects; (2) mechanisms enhancing PP variations in this population; (3) Analysis of pulsatile arterial hemodynamics as predictors of CV risk; and (4) Pulsatile hemodynamics and strategies lowering CV risk in the treatment of hypertension.
Chan Christopher T - - 2009
Cardiovascular mortality remains the leading cause of death in patients with end-stage renal disease. Frequent home hemodialysis in the form of short daily hemodialysis and nocturnal home hemodialysis has been suggested to correct multiple cardiovascular surrogate endpoints in observational and randomized controlled studies. This review discusses recent advances of intensive ...
Padwal Raj S - - 2009
OBJECTIVE: To provide updated, evidence-based recommendations for the diagnosis and assessment of adults with hypertension. OPTIONS AND OUTCOMES: The diagnosis of hypertension is dependent on appropriate blood pressure measurement, the timely assessment of serially elevated readings, the degree of blood pressure elevation, the method of measurement (office, ambulatory, home) and ...
Salles Gil F - - 2009
OBJECTIVE: The prognostic value of prolonged ventricular repolarization in patients with resistant hypertension is unknown. The aim of this prospective study was to investigate the usefulness of electrocardiographic QT-interval parameters as predictors of cardiovascular morbidity and mortality. METHODS: At baseline, 538 resistant hypertensive patients had five QT-interval components measured in ...
Poulter Neil R - - 2009
OBJECTIVES: To evaluate among individuals with diabetes whether major microvascular and macrovascular events are reduced by: (1) blood pressure lowering with a perindopril/indapamide combination compared with placebo; (2) intensive glucose control (targeting a haemoglobin A1c level of < or =6.5%) with a gliclazide MR-based regimen, compared with usual care. METHODS: ...
Mourad Jean-Jacques - - 2009
Cardiovascular disease is responsible for 70% of all mortality among patients with type 2 diabetes and is also a major contributor to diabetes-related healthcare costs. The ADVANCE trial clearly demonstrated that a simple and easily applicable pharmacological strategy based on perindopril/indapamide fixed combination could substantially reduce total and cardiovascular mortality ...
Paynter Nina P - - 2009
We examined whether a hypertension risk prediction model based on clinical characteristics and blood biomarkers might improve on risk prediction based on current blood pressure alone. A prospective cohort of 14,822 normotensive women aged 45 years and older were followed over 8 years beginning in 1992 for the development of ...
Kannel William B - - 2009
Framingham Heart Study cardiovascular disease prospective population epidemiologic research has played an important role in the evolution of modern cohort study design and the advancement of preventive cardiology. To date no single essential factor has been identified; multiple interrelated factors are promoting increased risk for development of CHD. Elevated blood ...
Addo J - - 2009
The association of socioeconomic position and cardiovascular disease risk factors in low- and middle-income countries has not been as consistent as that reported from high-income countries. A cross-sectional study of 1015 participants from seven civil service departments in Accra, Ghana, was conducted in 2006. Hypertension was diagnosed when the mean ...
Fallo Francesco - - 2009
Current evidence indicates a strong association between Cushing's syndrome, characterized by a cluster of systemic complications and increased cardiovascular risk. The biological link is cortisol overproduction, which influences various pathogenetic processes leading to cardiovascular damage, a main cause of increased mortality. Anthropometric and biochemical profile (including fasting glucose, lipids, potassium ...
Mulazzi Isabelle - - 2009
We designed a cross-sectional study to determine whether 6-item self-administered questionnaires addressing difficulties in taking treatment provide independent and relevant information on uncontrolled hypertension in high-risk cardiovascular patients seen in general practice. Patients with both treated hypertension and a history of vascular diseases-myocardial infarction, stroke, or peripheral artery disease-were included. ...
Ecder Tevfik - - 2009
Cardiovascular problems are a major cause of morbidity and mortality in patients with autosomal-dominant polycystic kidney disease (ADPKD). Hypertension is a common early symptom of ADPKD, and occurs in approximately 60% of patients before renal function has become impaired. Hypertension is associated with an increased rate of progression to end-stage ...
Knecht Stefan - - 2009
Vascular pathology impairs cognition and impaired cognition increases the risk of dementia. Hypertension is arguably the vascular risk factor that can be reverted best. Here we estimated the effect magnitude of hypertension by determining the variance in cognition explained by systolic blood pressure (sBP) in non-demented community-dwelling individuals. We recruited ...
Martins Maria João - - 2010
In their recent paper, Cheung et al [B.M. Cheung, K.L. Ong, L.Y. Wong, Elevated serum alkaline phosphatase and peripheral arterial disease in the United States National Health and Nutrition Examination Survey 1999-2004. Int J Cardiol 2008 (Electronic publication ahead of print)] described a significant association between serum alkaline phosphatase levels ...
M'Buyamba-Kabangu Jean-René - - 2009
As a consequence of hypertension, sub-Saharan Africa faces an epidemic of cardiovascular disease. We assessed in-hospital mortality among patients admitted for hypertension-related diseases to two city hospitals in Mbuji Mayi, Congo. On admission, we obtained anthropometric measurements, blood pressure, information on cardiovascular risk factors, and on the awareness and treatment ...
Dahle Cheryl L - - 2009
Advanced age is associated with decline in many areas of cognition as well as increased frequency of vascular disease. Well-described risk factors for vascular disease, such as diabetes and arterial hypertension, have been linked to cognitive deficits beyond those associated with aging. To examine whether vascular health indices such as ...
Li Fuzhong - - 2009
Few studies have examined interaction effects between person and environment, especially for cardiovascular disease (CVD) risk. The purpose of this study was to examine built environment characteristics and resident health behaviors as they relate to change in blood pressure, an important component of CVD. Participants (N=1145, aged 50-75 at baseline) ...
Heerspink Hiddo J Lambers - - 2009
Patients undergoing dialysis have a substantially increased risk of cardiovascular mortality and morbidity. Although several trials have shown the cardiovascular benefits of lowering blood pressure in the general population, there is uncertainty about the efficacy and tolerability of reducing blood pressure in patients on dialysis. We did a systematic review ...
May Ole - - 2009
AIM: The aim of this study was to assess risk factors for bleeding complications after elective coronary angiography (CA). METHODS AND RESULTS: We consecutively included 1,000 patients scheduled for elective diagnostic CA using the femoral approach. A bleeding complication was defined as formation of a hematoma >/=5 cm, severely oozing ...
Licht Carmilla M M - - 2009
The present study compared blood pressure levels between subjects with clinical anxiety and depressive disorders with healthy controls. Cross-sectional data were obtained in a large cohort study, the Netherlands Study of Depression and Anxiety (N=2981). Participants were classified as controls (N=590) or currently or remittedly depressed or anxious subjects (N=2028), ...
Sever Peter S - - 2009
BACKGROUND: We have reported the benefits of atorvastatin and of an amlodipine-based regimen on coronary heart disease (CHD) events in hypertensive patients in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). We report further analyses on the combined benefits of these interventions. METHODS: 19,342 hypertensive patients were randomised to either an amlodipine ...
Sandvei Marie Søfteland - - 2009
BACKGROUND AND PURPOSE: The morbidity and mortality of subarachnoid hemorrhage (SAH) are high, and established risk factors are scarce. We prospectively assessed the association of blood pressure, smoking, and body mass with the risk of aneurysmal SAH. METHODS: All residents >or=20 years were invited to the Nord-Trøndelag Health (HUNT) Study ...
Patten Scott B - - 2009
OBJECTIVE: To determine whether major depression (MD) leads to an increased risk of new-onset high blood pressure diagnoses. METHODS: The data source was the Canadian National Population Health Survey (NPHS). The NPHS included a short-form version of the Composite International Diagnostic Interview (CIDI-SF) to assess MD and collected self-report data ...
Dünser Martin W - - 2009
OBJECTIVE: To evaluate the association between arterial blood pressure (ABP) during the first 24 h and mortality in sepsis. DESIGN: Retrospective cohort study. SETTING: Multidisciplinary intensive care unit (ICU). PATIENTS AND PARTICIPANTS: A total of 274 septic patients. INTERVENTIONS: None. MEASUREMENTS AND RESULTS: Hemodynamic, and laboratory parameters were extracted from ...
Lachouri Mohand - - 2009
Analysis of changes in blood pressure with a two-year interval, and of factors associated with this change, in a large cohort of elderly individuals. Follow-up of a cohort of 9294 individuals aged 65 years and over recruited from the general population for Study 3C. Changes in blood pressure are defined ...
Mueck Alfred O - - 2009
Progestogens were mostly used in hormone replacement therapy (HRT) in the postmenopause. Therefore, our knowledge about cardiovascular effects mainly originates from studies using HRT, whereby the progestogen effects were assessed according to clinical endpoints, metabolic effects and influence on vascular markers in vitro or in vivo, respectively. Furthermore, the progestogens ...
Li Fuzhong - - 2009
OBJECTIVE: Few studies have examined interaction effects between person and environment, especially for cardiovascular disease (CVD) risk. The purpose of this study was to examine built environment characteristics and resident health behaviors as they relate to change in blood pressure, an important component of CVD. METHODS: Participants (N=1,145, aged 50-75 ...
Goldberg Ivan - - 2009
Glaucoma management aims to preserve patients' quality of life by halting progressive visual loss. Intraocular pressure reduction is the pivotal strategy: we establish a "target" pressure based on extent of visual damage, threat to visual performance, risk profile for further damage, pre-treatment pressure levels, family history and a patient's life ...
Bo Simona - - 2009
OBJECTIVE: A Few population-based studies have shown that high-normal blood pressure clusters with other cardiovascular risk factors. Increased inflammation, endothelial dysfunction, oxidative stress, and reduced adiponectin values have sporadically been reported in these patients. METHODS: We cross-sectionally compared blood pressure categories with cardiovascular risk factors in an adult population-based cohort ...
Mallamaci Francesca - - 2009
Establishing solutes that accumulate in body fluids in renal insufficiency as authentic uremic toxins is a process demanding in vitro and in vivo animal experiments as well as observational and interventional studies in humans. Asymmetric dimethylarginine (ADMA) is listed among the few uremic solutes close to the inference criteria for ...
Woo Young Sup - - 2009
BACKGROUND: Numerous reports have linked atypical antipsychotics, especially clozapine and olanzapine, to the development of cardiovascular risk factors. In this retrospective chart review study, we investigated the blood pressure changes in Korean schizophrenic inpatients treated with clozapine or olanzapine. METHOD: We reviewed the medical record of schizophrenic patients treated with ...
Newell Maxine - - 2009
In the United Kingdom, the morbidity and mortality associated with hypertension is much higher in Blacks than in Whites. We studied a convenience sample of 312 persons aged 25-79 years from 17 predominantly Black Seventh-Day Adventist churches across London by using the health belief model to examine their beliefs about ...
van Bruchem-Visser Rozemarijn L - - 2009
BACKGROUND: The prevalence of cardiovascular disease and Alzheimer's disease (AD) increases with age. A number of studies have demonstrated an association between AD and cardiovascular risk factors and disease. However, data are inconsistent. METHODS: Cross-sectional observational study in a geriatric outpatient population. Analysis of data from 327 patients diagnosed with ...
Royall Donald - - 2009
Forty percent of nondemented octogenarians have Braak stages consistent with insular involvement, and may be at risk for "age-related" autonomic dysfunction. The authors examined the association between insular resting cerebral blood flow (rCBF) and cardiovascular functions in 29 nondemented elderly subjects who were highly screened to exclude comorbid cardiovascular disease. ...
Palm-Meinders Inge H - - 2009
BACKGROUND AND PURPOSE: Wall shear stress (WSS) is the frictional force exerted by the circulating blood on the endothelium. Low systolic WSS is identified as an atherosclerotic risk factor. Recently, also the importance of diastolic WSS has been described. Still, it is unknown whether diastolic WSS carries similar cardiovascular risk ...
Kehoe Patrick G - - 2009
The pathology of Alzheimer's disease (AD) features amyloid beta peptide deposition, intracellular neurofibrillary tangles and deficits in the cholinergic pathway. Abnormal blood pressure is recognised as a risk factor for the development of AD, although the underlying mechanisms remain unproven. This review proposes angiotensins and associated enzymatic pathways as important ...
Patel Jeetesh V - - 2009
BACKGROUND: Abnormal adipocyte function is implicated in the coalition of multiple cardiovascular risk factors, where aberrant circulating levels of the adipose-derived hormones adiponectin, leptin, and tumour necrosis factor (TNF) alpha may provide the putative link between hypertension and increased cardiovascular risk. The pragmatic utility of these 'adipocytokines' in the clinical ...
Famodu A A - - 2009
BACKGROUND: Some epidemiological studies have found anthropometric indices to be related to cardiovascular disease risk factors. Fibrinogen--an acute phase reactant protein--is central in the haemostatic system. Its associations with cardiovascular diseases have been well documented. A possible association between measures of body fat and fibrinogen has been reported. AIMS: To ...
Qiu Chengxuan - - 2009
BACKGROUND/AIM: Midlife high blood pressure is linked to late-life dementia. We sought to investigate the temporal relation of blood pressure to the risk of dementia and Alzhei-mer's disease (AD) among older adults. METHODS: A dementia-free cohort (n = 422) aged > or =81 years was followed for 3 years to ...
Musini Vijaya M - - 2009
Elevated blood pressure (known as hypertension) increases with age, and most rapidly over age 60. Systolic hypertension is more strongly associated with cardiovascular disease than diastolic hypertension, and occurs more commonly in older people. It is important to know the benefits and harms of antihypertensive treatment of hypertension in this ...
Langrish Jeremy P JP Centre for Cardiovascular Sciences, Edinburgh University, Edinburgh, UK. - - 2009
Exposure to air pollution is an important risk factor for cardiovascular morbidity and mortality, and is associated with increased blood pressure, reduced heart rate variability, endothelial dysfunction and myocardial ischaemia. Our objectives were to assess the cardiovascular effects of reducing air pollution exposure by wearing a facemask. In an open-label ...
Gurusamy Kurinchi Selvan KS University Department of Surgery, Royal Free Hospital and University College School of Medicine, 9th Floor, Royal Free Hospital, Pond Street, London, UK, NW3 2QG. - - 2009
A pneumoperitoneum of 12 to 16 mmHg is used for laparoscopic cholecystectomy. Lower pressures are claimed to be safe and effective in decreasing cardiopulmonary complications and pain. To assess the benefits and harms of low pressure pneumoperitoneum compared with standard pressure pneumoperitoneum in patients undergoing laparoscopic cholecystectomy. We searched The ...
Bradley T Douglas - - 2009
Obstructive sleep apnoea (OSA) is a common disorder in which repetitive apnoeas expose the cardiovascular system to cycles of hypoxia, exaggerated negative intrathoracic pressure, and arousals. These noxious stimuli can, in turn, depress myocardial contractility, activate the sympathetic nervous system, raise blood pressure, heart rate, and myocardial wall stress, depress ...
Martínez Pérez Sebastián R - - 2009
OBJECTIVES: The aim of this study is to determine the influence that different risk factors (age, gender, obesity, smoking, inactivity, diabetes mellitus and previous diagnosis of arterial hypertension) have on arterial pressure, and to determine the prevalence of patients that have high blood pressure and hypertension but have not received ...
de Liefde Inge I - - 2008
OBJECTIVE: A decline in systolic blood pressure during exercise is thought to be a sign of severe coronary artery disease. However, no studies have yet examined this effect in patients with known or suspected peripheral arterial disease. Therefore, we investigated the prognostic value of hypotensive blood pressure response after single-stage ...
Hawkesworth Sophie - - 2009
Animal studies have demonstrated that altering the maternal diet during pregnancy affects offspring disease risk. Data from human subjects on the early-life determinants of disease have been derived primarily from birth-weight associations; studies of the impact of the maternal diet are scarce and inconsistent. Investigating CVD risk factors in the ...
Karakitsos Dimitrios - - 2009
AIM: We evaluated the utility of impedance cardiography (IC) in elderly hemodialysis (HD) patients with coronary artery disease (CAD). PATIENTS AND METHODS: Seventy-five HD patients (30 with CAD) participated. IC cardiac output (ICCO), systemic vascular resistance and pulse pressure (PP) were calculated at baseline, and 30 and 180 days after ...
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