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Pahlevan Niema M NM Medical Engineering, Division of Engineering and Applied Sciences, California Institute of Technology, 1200 East California Boulevard, MC 301-46, Pasadena, CA 91125, - - 2014
The reductionist approach has dominated the fields of biology and medicine for nearly a century. Here, we present a systems science approach to the analysis of physiological waveforms in the context of a specific case, cardiovascular physiology. Our goal in this study is to introduce a methodology that allows for ...
Guardiola Juan J Robley Rex VA Medical Center, University of Louisville, Louisville, Ky., - - 2014
Background: Positive end-expiratory pressure (PEEP) is commonly used in clinical settings. It is expected to affect the input from slowly adapting pulmonary stretch receptors (SARs), leading to altered cardiopulmonary functions. However, we know little about how SARs behave during PEEP application. Objectives: Our study aimed to characterize the behavior of ...
James Gary D GD Department of Anthropology, Binghamton University, Binghamton, New York, 13902; Decker School of Nursing, Department of Bioengineering, Binghamton University, Binghamton, New York, - - 2014
As daily environments change, behavior and activity also change and as blood pressure (BP) and heart rate (HR) are allostatically tied to these factors, one might expect that environments that elicit the greatest behavioral/activity variation should also evince the highest BP and HR variability [standard deviation (SD) or coefficient of ...
Abbas Amr E AE Department of Cardiovascular Medicine, Beaumont Health Systems, Royal Oak, - - 2014
In patients with aortic stenosis (AS) and eccentric transaortic flow, greater pressure loss occurs as the jet collides with the aortic wall together with delayed and diminished pressure recovery. This leads to the elevated transaortic valve pressure gradients noted on both Doppler and cardiac catheterization. Such situations may present a ...
Kim Hack-Lyoung HL Division of Cardiology, Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, - - 2014
Because of the invasive nature of catheterization, limited information is available on hemodynamic interaction between the left ventricle and aorta using invasive aortic pressure monitoring. Our aim was to investigate whether parameters of invasively measured central aortic pressure waveform were related with those of left ventricular (LV) diastolic function. A ...
Lacy Peter S PS University College London and the National Institute for Health Research University College London Hospitals Biomedical Research Centre, - - 2014
Brachial blood pressure increases with exercise and an excessive rise predicts increased cardiovascular risk. Measurement of brachial blood pressure alone may exaggerate the true blood pressure elevation due to exercise-induced change to pressure amplification. Whether blood pressure-lowering treatment modulates pressure amplification during exercise is unknown. Thirty-two participants with stage 1-2 ...
Kim Jeong Yeon JY Department of Neurology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, - - 2014
We investigated the relationship between transcranial Doppler (TCD) pulsatility index (PI) and central aortic pressure by measurement of the aortic augmentation index (AIx). We enrolled 148 consecutive patients with a diagnosis of acute ischemic stroke. Patients were eligible for the study if they experienced their first ischemic stroke within the ...
Hermans Hadewich H KULeuven - - 2014
Transverse aortic constriction (TAC) and Angiotensin II (AngII)subcutaneous osmotic pump infusion are frequently used murine models of pressure overload hypertrophy. The aim of this paper is to investigate time- and stressor dependent functional and structural changes using echocardiographic B-mode, M-mode and Doppler characterization. Ten weeks old male C57BL6/J wild-type mice ...
Ahn Hyo-Suk HS Division of Cardiology, Department of Internal Medicine, Cardiovascular Center, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, South - - 2014
Pulmonary hypertension (PHT) is not uncommon in patients with aortic stenosis (AS) and portends a dismal prognosis. We attempted to determine the prevalence of PHT and to identify contributors to its development in patients with moderate or severe AS. A total of 189 patients were enrolled. Patients were divided into ...
Mishima Akira A Department of Cardiovascular Surgery, Graduate School of Medical Sciences, Nagoya City University, Nagoya, - - 2014
The aim of this study was to evaluate the mid-term outcomes of a strategy for repair of coarctation of the aorta (CoA) and hypoplastic aortic arch (HAA) with a modified, extended end-to-end repair that preserves the lesser curvature of the aortic arch in neonates with intracardiac defects. We studied 21 ...
Rateri Debra L DL Saha Cardiovascular Research Center, University of Kentucky, Lexington, - - 2014
Angiotensin II (Ang II) promotes development of ascending aortic aneurysms (AAs), but progression of this pathology is undefined. We evaluated factors potentially involved in progression, and determined the temporal sequence of tissue changes during development of Ang II-induced ascending AAs. Ang II infusion into C57BL/6J mice promoted rapid expansion of the ascending aorta, ...
van Riel Annelieke C M J AC Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands; ICIN - Netherlands Heart Institute, Utrecht, The - - 2014
Chronic mitral regurgitation (MR) often leads to diminished right ventricular (RV) function due to long-standing pressure and volume overload. Surgical intervention often adds to the preexisting RV dysfunction. Percutaneous mitral valve (MV) repair can reduce MR, but to what extent this affects the right ventricle is unknown. Consecutive patients scheduled ...
Torjesen Alyssa A AA From the Cardiovascular Engineering, Inc, Norwood, MA (A.A.T., J.D.G., V.B.); Icelandic Heart Association, Kopavogur, Iceland (S.S., T.A., V.G.); Leiden University Medical Center, Leiden, The Netherlands (J.J.M.W., A.d.R.); University of Iceland, Reykjavik, Iceland (T.A., V.G.); and National Institute on Aging, National Institutes of Health, Bethesda, MD (L.J.L., - - 2014
High pulse pressure, a major cardiovascular risk factor, has been attributed to medial elastic fiber degeneration and aortic dilation, which transfers hemodynamic load to stiffer collagen. However, recent studies suggest higher pulse pressure is instead associated with smaller aortic diameter. Thus, we sought to elucidate relations of pulse pressure with ...
Benito-Lopez Fernando F CIC microGUNE, Arrasate-Mondragón, Spain. fbenito@cicmicrogune.es - - 2014
This paper reports for the first time the use of a cross-linked poly(N-isopropylacrylamide) ionogel encapsulating the ionic liquid 1-ethyl-3-methylimidazolium ethyl sulphate as a thermoresponsive and modular microfluidic valve. The ionogel presents superior actuation behaviour to its equivalent hydrogel. Ionogel swelling and shrinking mechanisms and kinetics are investigated as well as ...
Hua D M DM Guangzhou Institute of Respiratory Disease, State Key Laboratory of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, No. 151 Yanjiang Road, Guangzhou, - - 2014
Controlled twitch mouth pressure (Tw Pmo) via the use of a two-way non-rebreathing valve is a new method to assess diaphragm contractility. The optimal trigger threshold was confirmed. We sought to determine the optimal trigger threshold for 17 healthy subjects (29±4 years) and 17 COPD patients (64±10 years). The Tw ...
Protogerou Athanase D AD aHypertension Center and Cardiovascular Research Laboratory, 1st Department of Propaedeutic Medicine, 'Laiko' Hospital, Medical School bBiomedical Engineering Unit, 1st Department of Cardiology, 'Hippokration' Hospital, Medical School, National and Kapodistrian University of Athens cHypertension Center, 3rd University Department of Medicine, 'Sotiria' Hospital, Athens, Greece dParis Descartes University, AP-HP, Diagnosis and Therapeutic Center, Hôtel-Dieu, Paris, - - 2014
To test the hypothesis that left-ventricular hypertrophy (LVH) is better associated with aortic, than brachial, 24-h average blood pressure (BP) in individuals with hypertension. The office aortic BP is associated better with organ damage, such as LVH, than the office brachial BP; whether the 24-h average aortic BP associates better ...
Abid Leila L Cardiology Department, University Hedi Chaker Hospital, Medicine University of Sfax, - - 2014
Conventional echocardiographic (ECHO) parameters of systolic and diastolic func-tion of the left ventricular (LV) have been shown to be load dependent. However, the impact of pre-load reduction on tissue Doppler (TD) parameters of LV function is incompletely understood. To evaluate the effect of a single hemodialysis (HD) session on LV ...
Oyri Karl K The Intervention Centre, Oslo University Hospital, Oslo, Norway and Institute of Clinical Medicine, University of Oslo , Oslo , - - 2014
Abstract Objectives: To evaluate the level of agreement of simulated wired and Wi-Fi vital signs output from an intra-aortic balloon pump during exposure to electromagnetic interference from frequency overlapping ZigBee sensors. Material and methods: A series of experiments with interference from single and multiple ZigBee sensors were benchmarked with wired ...
Murakami Tomoaki T Department of Cardiology, Chiba Children's Hospital, Japan. Electronic address: - - 2014
Excessive aortic pressure wave reflection is one of the risk factors of cardiovascular diseases. In some clinical course of congenital heart diseases, the elevated pressure wave reflection has been reported. The purpose of this study is to elucidate the risk factors of the enhanced pressure wave reflection in adult patients ...
Covella Michele M aDivision of Internal Medicine and Hypertension Unit, Department of Medical Sciences, University of Torino bDepartment of Health Science, University of Milano-Bicocca and Istituto Auxologico Italiano, Italy *Michele Covella and Alberto Milan contributed equally to the writing of this - - 2014
The risk of thoracic aortic dissection is strictly related to the diameter of the ascending aorta. Arterial hypertension represents a major risk factor for the development of aortic dissection and is thought to be directly involved in the pathogenesis of aortic aneurysms. Recent studies have suggested a high prevalence of ...
Seibert Felix S FS Charité - Campus Benjamin Franklin, Dept. of Nephrology, Berlin, Germany; Universitätsklinik Marienhospital, Ruhr-University Bochum, Medizinische Klinik I, Herne, - - 2014
Calcineurin inhibitors (CNI) are potent vasoconstrictors and induce an acceleration of arteriosclerosis, thus contributing to the cardiovascular risk after renal transplantation. The present study compares the impact of belatacept and cyclosporine A (CsA) on arterial stiffness and central aortic blood pressure. We performed a case-control study in 46 patients (23 ...
Hachiya Kenta K Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, - - 2014
The present study tested the hypothesis that epicardial fat may be associated with augmented central aortic pressure and impaired left ventricular (LV) function. We studied 134 consecutive patients undergoing left-sided cardiac catheterization for coronary artery disease (CAD) and examined the relation of epicardial fat volume measured by multi-detector computed tomography ...
De Groote Katya K Division of Paediatric Cardiology, Department of Paediatrics, Ghent University Hospital, De Pintelaan 185, 3K12D, Administratie pediatrie, B-9000, Ghent, Belgium, - - 2014
Hypertension in Turner syndrome (TS) is a multifactorial, highly prevalent and significant problem that warrants timely diagnosis and rigorous treatment. The objective of this study was to investigate the association between abnormal aortic arch morphology and hypertension in adult TS patients. This was a single centre retrospective study in 74 ...
Roetker Nicholas S NS Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, - - 2014
Previous research suggests that elevated pulse pressure (PP) is a risk factor for atrial fibrillation (AF) independently of mean arterial pressure (MAP). PP may serve as an indirect measure of aortic stiffness (reduced distensibility), but whether directly measured aortic distensibility is related to risk for AF has not yet been ...
Hashimoto Junichiro J aDepartment of Blood Pressure Research bDivision of Nephrology, Endocrinology, and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, - - 2014
A pathological connection between the heart and kidney is well recognized as a cardiorenal syndrome, but the underlying mechanism remains undetermined. We hypothesized that this connection is attributable to central haemodynamic alterations. In 386 patients with hypertension, the radial, carotid and femoral pressure waveforms were recorded with applanation tonometry to ...
Mohammadi Mohammad Taghi MT Department of Physiology and Biophysics, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: - - 2014
The present study examined genes transcription of tight junction (TJs) proteins of the blood-brain barrier (BBB) and detrimental effects on the brain tissue after acute hypertension.The experiment was performed in two groups of rats, sham and hypertensive. Rats were made acutely hypertensive by aortic constriction above the renal arteries. After ...
Davis Margot K MK Divisions of *Cardiovascular Medicine and †Cardiovascular Surgery, Stanford University School of Medicine, Stanford, - - 2014
Microbubbles formed by cavitation have been frequently reported in patients with mechanical heart valves (MHVs), but have not previously been described in patients with continuous-flow left ventricular assist devices (LVADs). Obstruction of the LVAD circuit by thrombus, outflow graft kinking, or cannula malposition may cause high pressure gradients and turbulent ...
Burgoyne Steven - - 2014
We intended to determine if acute baroreflex activation therapy (BAT) increases venous capacitance and aortic conductance. BAT is effective in resistant hypertension but its effect on the systemic vasculature is poorly understood. Left ventricular (LV) and aortic pressures and sub-diaphragmatic aortic and caval flows (ultrasonic) were measured in 6 anesthetized ...
Schultz Martin G MG From the Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia (M.G.S., A.H., J.E.S.); International Centre for Circulatory Health, Imperial College London, London, United Kingdom (J.E.D., M.M, M.D.); Royal Hobart Hospital, Hobart, Tasmania, Australia (S.P.); and Institute of Cardiovascular Science, University College London, London, United Kingdom - - 2014
Aortic reservoir pressure indices independently predict cardiovascular events and mortality. Despite this, there has never been a study in humans to determine whether the theoretical principles of the mathematically derived aortic reservoir pressure (RPderived) and excess pressure (XPderived) model have a real physiological basis. This study aimed to directly measure ...
Vukicevic M M 1Mechanical and Bioengineering Engineering, Clemson University, Clemson, SC, USA 2Laboratory of Biological Structure Mechanics, Politecnico di Milano, Milan, Italy 3Cardiothoracic Surgery, Great Ormond Street Hospital for Children, London, United - - 2014
Respiration influences the subdiaphragmatic venous return in the total cavopulmonary connection (TCPC) of the Fontan circulation whereby both the inferior vena cava (IVC) and hepatic vein flows can experience retrograde motion. Controlling retrograde flows could improve patient outcomes. Using a patient-specific model within a Fontan mock circulatory system with respiration, ...
Wybraniec Maciej T MT First Department of Cardiology, Medical University of Silesia, Upper Silesia Medical Center, Katowice, Poland. Electronic address: - - 2014
The study aimed to evaluate plasma renalase level, a recently discovered kidney-derived catecholamine-metabolizing enzyme in patients after successful repair of aortic coarctation, with special consideration of arterial hypertension in the context of underlying process of arterial remodeling. This case-control study covered 50 consecutive patients after Dacron patch repair of aortic ...
Trudeau Luc L Cardiovascular Prevention Centre, Department of Internal Medicine, Jewish General Hospital, McGill University, Montreal, Québec, Canada. Electronic address: - - 2014
The measurement of central blood pressure has generated interest as a tool in predicting cardiovascular events. The purpose of this article is to review the meaning and measurement of the central blood pressure and consider its potential value as an index of the antihypertensive response. Indirect estimation of central aortic ...
Lennon-Edwards Shannon - - 2014
Increased potassium intake has been shown to lower blood pressure (BP) even in the presence of high sodium consumption however the role of dietary potassium on vascular function has received less attention. The aim of this study was to evaluate the relationship between habitual intake of sodium (Na) and potassium ...
Yu Danyang D School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, - - 2014
In previous research, time-delay (Δt) was a more important parameter than the reflection coefficient in the individual transfer function of central aortic pressure reconstruction. The Δt can be obtained by electrocardiography (ECG) or phonocardiography (PCG). Because the pre-ejection period remains an uncertain factor, the present study used ECG and PCG ...
Zhang Yongxue Y Division of Vascular Surgery, Changhai Hospital, Shanghai, PR - - 2014
Objective: This study sought to elucidate the underlying hemodynamic mechanisms involved in the longitudinal propagation of acute, type-B aortic dissections. Methods: Three-dimensional patient-specific aortic geometry was reconstructed from computed tomography images of 3 cases, followed by computational fluid dynamic analysis using finite-element analysis modeling. Three models were reconstructed; the normal-aortic ...
Narayanan Nithya N *Department of Physiology and Biophysics, University of Louisville School of Medicine, and †Department of Exercise Physiology, University of Louisville, Louisville, Kentucky, - - 2014
Hyperhomocysteinemia (HHcy) is prevalent in patients with hypertension and is an independent risk factor for aortic pathologies. HHcy is known to cause an imbalance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs), leading to the accumulation of collagen in the aorta and resulting in stiffness and development of ...
Pesek Matthew M 1Department of Pediatrics, Division of Pediatric Critical Care, Baylor College of Medicine, Texas Children's Hospital, Houston, TX 2Department of Anesthesiology, Division of Pediatric Anesthesiology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX 3College of Osteopathic Medicine, Touro University, Vallejo, CA 4Department of Pediatrics, Division of Neonatology, Baylor College of Medicine, Texas Children's Hospital, Houston, - - 2014
The upper limit of cerebrovascular pressure autoregulation (ULA) is inadequately characterized. To delineate the ULA in an infant swine model. Neonatal piglets with sham surgery (n=9), interventricular fluid infusion (INF; n=10), controlled cortical impact (CCI; n=10), or impact + infusion (CCI + INF; n=11) had intracranial pressure monitoring and bilateral ...
Morrison Jonathan J JJ The Academic Department of Military Surgery & Trauma, Royal Centre for Defence Medicine, Birmingham, United Kingdom; The United States Army Institute of Surgical Research, Fort Sam Houston, Texas; Academic Unit of Surgery, Glasgow Royal Infirmary, Glasgow, United - - 2014
Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a hemorrhage control and resuscitative adjunct that has been demonstrated to improve central perfusion during hemorrhagic shock. The aim of this study was to characterize the systemic inflammatory response associated and cardiopulmonary sequelae with 30, 60, and 90 min of balloon occlusion ...
Rengier Fabian F 1 University Hospital Heidelberg, Department of Diagnostic and Interventional Radiology, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany ; 2 German Cancer Research Center (dkfz) Heidelberg, Department of Radiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany ; 3 Karlsruhe Institute of Technology (KIT), Department of Informatics, Institute for Anthropomatics and Robotics, Adenauerring 2, 76131 Karlsruhe, Germany ; 4 University Hospital Heidelberg, Department of Paediatric Cardiology, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany ; 5 Inselspital, University Hospital Bern, Institute for Diagnostic, Interventional and Pediatric Radiology (DIPR), Freiburgstr. 10, 3010 Bern, - - 2014
To develop a method for computing and visualizing pressure differences derived from time-resolved velocity-encoded three-dimensional phase-contrast magnetic resonance imaging (4D flow MRI) and to compare pressure difference maps of patients with unrepaired and repaired aortic coarctation to young healthy volunteers. 4D flow MRI data of four patients with aortic coarctation ...
Ripley Toni L TL University of Oklahoma College of Pharmacy, Oklahoma City, OK, - - 2014
To review the pharmacology, pharmacokinetics, and pharmacodynamic properties of commonly used β-blockers (atenolol, carvedilol, metoprolol succinate, metoprolol tartrate, and nebivolol). A MEDLINE literature search (1966-May 2013) was performed using the following key terms: hypertension, β-blockers, atenolol, carvedilol, metoprolol tartrate, metoprolol succinate, nebivolol, pharmacology, pharmacodynamics, pharmacokinetics, blood pressure, metabolic, lipid, central ...
Ikeda Shohei S From the Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan (S.I., K.S., N.K., S.M., K.S., J.O., T.S., Y.F., Y.S., H.S.); and Department of Molecular Genetics, Institute of Biomedical Sciences, Fukushima Medical University School of Medicine, Fukushima, Japan (Ke. Kobayashi, Ka. - - 2014
Right ventricular (RV) failure is the leading cause of death in various cardiopulmonary diseases, including pulmonary hypertension. It is generally considered that the RV is vulnerable to pressure overload as compared with the left ventricle (LV). However, as compared with LV failure, the molecular mechanisms of RV failure are poorly ...
Thio M M Neonatal Services, The Royal Women's Hospital, , Melbourne, - - 2014
In neonatal resuscitation, the use of a sustained inflation (SI) may facilitate lung aeration. Previous studies comparing different resuscitation devices have shown that one model of self-inflating bag (SIB) could not deliver an SI. We aimed to compare the delivery of an SI using four SIBs with that of a ...
Juraszek Andrzej A Center for Medical Physics and Biomedical Engineering, Vienna, - - 2014
The aim of the study was to simulate the effect of different bicuspid aortic valve configurations on the dynamic pressure distribution in the ascending aorta. Aortic specimens were harvested from adult domestic pigs. In Group 1, bicuspidalization was created by a running suture between the left and the right coronary ...
Everett T R TR Fetal Medicine Department, Rosie Hospital, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 2QQ, - - 2014
To determine the effects of in vivo S-nitrosoglutathione infusion on cardiovascular, platelet function, proteinuria and biomarker parameters in early-onset pre-eclampsia. We performed an open-label dose-ranging study of S-nitrosoglutathione in early-onset pre-eclampsia. Six women with underwent S-nitrosoglutathione infusion whilst receiving standard therapy. S-nitrosoglutathione dose was incrementally increased to 100μg/min whilst maintaining ...
Theilade Simone S Diabetes Complication Research Department, Steno Diabetes Center, Gentofte, - - 2014
We sought to investigate associations between central hemodynamic parameters (estimated from radial pulse wave analyses (PWAs)), cardiovascular disease (CVD), and albuminuria in type 1 diabetes. We conducted an observational study of 636 type 1 diabetes patients. Central hemodynamics were measured by PWA as central aortic systolic pressure (CASP), central aortic ...
Corazza Ivan I Experimental, Diagnostic and Specialty Medicine Department, University of Bologna, Via Massarenti, 9, 40138 Bologna, Italy. Electronic address: - - 2014
Aortic counterpulsation (IABP) consists in an ECG-controlled forced deflation and inflation of a balloon positioned in the aorta. The device is designed to decrease the ventricular afterload during systole and to increase the coronary driving pressure during diastole. In biomechanical terms, the IABP improves the mechanical matching between the pump ...
Bargiotas Ioannis I Sorbonne Universités, UPMC Univ Paris 06, UMR 7371, UMR_S 1146, Laboratoire d'Imagerie Biomédicale, Paris, France; INSERM, UMR_S 1146, Laboratoire d'Imagerie Biomédicale, Paris, France; CNRS, UMR 7371, Laboratoire d'Imagerie Biomédicale, Paris, - - 2014
We sought to noninvasively estimate aortic impedance indices from MR and tonometric data. MR aortic velocity-encoded and carotid applanation tonometry pressure data of 70 healthy subjects (19-79 years) were used to calculate the following indices from impedance spectrum: (i) characteristic impedance (Zc) reflecting pulsatile component of left ventricular (LV) afterload, ...
Huang Feng F * The State Key Laboratory of Fluid Power Transmission and Control, Zhejiang University, Hangzhou, - - 2014
Sufficient pulsation is important for physiological perfusion if adequate flow is to be guaranteed. A fuzzy control method for rotary blood pumps using active speed modulation is proposed in this paper. It maintains the mean aortic pressure to provide sufficient perfusion while it simultaneously enhances the pulse pressure. The controller ...
Pabittei Dara R DR Department of Cardiothoracic Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The - - 2014
The low welding strength of laser-assisted vascular anastomosis (LAVA) has hampered the clinical application of LAVA as an alternative to suture anastomosis. To improve welding strength, LAVA in combination with solder and polymeric scaffolds (ssLAVA) has been optimized in vitro. Currently, ssLAVA requires proof-of-concept in a physiologically representative ex vivo model before ...
Bailly L L Aix Marseille Université, CNRS, Centrale Marseille, IRPHE UMR 7342, 13384 Marseille, France. Electronic address: - - 2014
This work proposes an in vitro tensile testing protocol that is able to characterize abdominal aortic (AA) analogues under physiologically inspired mechanical loadings. Kinematic parameters are defined in agreement with in vivo measurements of aortic dynamics. A specific focus is given to the choice of the applied loading rates, deriving ...
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