Search Results
Results 301 - 350 of 1828
< 2 3 4 5 6 7 8 9 10 11 12 >
Cihan Abdullah - - 2012
Carbon dioxide injection into deep saline formations may induce large-scale pressure increases and migration of native fluid. Local high-conductivity features, such as improperly abandoned wells or conductive faults, could act as conduits for focused leakage of brine into shallow groundwater resources. Pressurized brine can also be pushed into overlying/underlying formations ...
Tamegai Hideyuki - - 2012
It is known that the facultative piezophile Shewanella violacea DSS12 alters its respiratory components under the influence of hydrostatic pressure during growth. This can be considered one of the mechanisms of bacterial adaptation to high pressure. In this study, we investigated the respiratory system of another well-studied piezophile, Photobacterium profundum ...
Parichatikanond Warisara - - 2012
Overactivation of the renin-angiotensin system is one of the most important risk factors for the development of hypertension. The use of the crude extracts and/or active compounds, such as anthocyanins and quercetin, of herbal plants that have antihypertensive effects is beneficial for decreasing of blood pressure level. However, the molecular ...
Nepple Kenneth G KG Division of Urology, Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA. - - 2013
Previous experimental research has reported minimal differences in pressure maintenance between different versions of standard insufflators (SI). However, a recent report identified potential clinical benefits with a valveless pressure barrier insufflator (PBI). We sought to perform a benchtop objective evaluation of SI and PBI systems. A rigid box system with ...
de Oliveira Fabricio Ferreira - - 2012
Normal pressure hydrocephalus is an unusual manifestation of systemic lupus erythematosus and its pathogenesis is still unclear. We report the case of a 39-year-old white woman with systemic lupus erythematosus who developed magnetic gait, speech difficulties, progressive memory impairment, urinary incontinence and episodes of involuntary closure of the eyelids. Signs ...
Ji Xiaoyan - - 2012
For CO2 geological storage, permitting impurities, such as H2S, in CO2 streams can lead to a great potential for capital and energy savings for CO2 capture and separation, but it also increases costs and risk management for transportation and storage. To evaluate the cost - benefits, using a recently developed ...
Melamed Roman - - 2012
OBJECTIVES: Invasive blood pressure monitoring is the most reliable method in critically ill patients. Noninvasive oscillometric pressure monitoring is also widely used in the ICU, and discrepancies between the methods are common. Inclusion of a blood-conserving device may influence the fidelity of the system and reliability of the invasive pressure ...
Etemadi M - - 2012
Congenital pulmonary hypoplasia is a devastating condition affecting fetal and newborn pulmonary physiology, resulting in great morbidity and mortality. The fetal lung develops in a fluid-filled environment. In this work, we describe a novel, implantable pressure sensing and recording device which we use to study the pressures present in the ...
Toal Corey B - - 2012
Calcium-channel blockers (CCBs) constitute a diverse group of compounds but are often referred to as a single homogeneous class of drug and the clinical responses indiscriminately summarized. Even within the dihydropyridine subgroup, there are significant differences in formulations, pharmacokinetics, durations of action and their effects on blood pressure, heart rate, ...
Kalupahana Nishan S - - 2012
The renin-angiotensin system (RAS) is classically known for its role in regulation of blood pressure, fluid and electrolyte balance. In this system, angiotensinogen (Agt), the obligate precursor of all bioactive angiotensin peptides, undergoes two enzymatic cleavages by renin and angiotensin converting enzyme (ACE) to produce angiotensin I (Ang I) and ...
Henderson Sarah - - 2012
Health professionals can fail to identify and treat serious illness or acute deterioration in children because of a lack of relevant training, experience or supervision. In Argyll and Bute in Scotland a standardised, monitoring system was initiated measuring six physiological parameters: temperature, pulse rate, respiratory rate, systolic blood pressure, oxygen ...
Groenewald Berlizé - - 2012
Gas exchange dynamics in insects is of fundamental importance to understanding evolved variation in breathing patterns, such as discontinuous gas exchange cycles (DGCs). Most insects do not rely solely on diffusion for the exchange of respiratory gases but may also make use of respiratory movements (active ventilation) to supplement gas ...
Antfolk Christian C Department of Measurement Technology and Industrial Electrical Engineering, Lund University, Lund, - - 2012
Lack of sensory feedback is a drawback in today's hand prostheses. We present here a non-invasive simple sensory feedback system, which provides the user of a prosthetic hand with sensory feedback on the arm stump. It is mediated by air in a closed loop system connecting silicone pads on the ...
Lion Thomas W - - 2012
Computer simulations of inhomogeneous soft matter systems often require accurate methods for computing the local pressure. We present a simple derivation, based on the virial relation, of two equivalent expressions for the local (atomistic) pressure in a molecular dynamics simulation. One of these expressions, previously derived by other authors via ...
Park Taehyun - - 2012
A novel thermoplastic fusion bonding method using a pressure-assisted boiling point (PABP) control system was developed to apply precise temperatures and pressures during bonding. Hot embossed polymethyl methacrylate (PMMA) components containing microchannels were sealed using the PABP system. Very low aspect ratio structures (AR = 1/100, 10 μm in depth ...
Marc Yannick - - 2012
Brain renin-angiotensin system hyperactivity has been implicated in the development and maintenance of hypertension. We reported previously in the brain that aminopeptidase A and aminopeptidase N are involved in the metabolism of angiotensin II and angiotensin III, respectively. By using in vivo specific and selective aminopeptidase A and aminopeptidase N ...
Hyam Jonathan A - - 2012
Deep brain stimulation (DBS) is an expanding field in neurosurgery and has already provided important insights into the fundamental mechanisms underlying brain function. One of the most exciting emerging applications of DBS is modulation of blood pressure, respiration and micturition through its effects on the autonomic nervous system. DBS stimulation ...
Hoppe Uta C - - 2012
BACKGROUND: Previous trials have demonstrated clinically significant and durable reductions in arterial pressure from baroreflex activation therapy (BAT), resulting from electrical stimulation of the carotid sinus using a novel implantable device. A second-generation system for delivering BAT, the Barostim neo™ system, has been designed to deliver BAT with a simpler ...
Kaczka David W - - 2012
The dynamic mechanical properties of the respiratory system reflect the ensemble behavior of its constituent structural elements. This study assessed the appropriateness of constant-phase descriptions of respiratory tissue viscoelasticity at various distending pressures. We measured the mechanical input impedance (Z) of the lungs, chest wall and total respiratory system in ...
Kimura Toshihiro - - 2012
No pressure: A simple monomeric tungstate, [WO(4) ](2-) , serves as a highly efficient homogeneous catalyst for various transformations of CO(2) at atmospheric pressure. The tungsten-oxo moiety activates CO(2) and the substrate simultaneously. The catalyst system is high yielding and applicable to a wide range of substrates such as amines, ...
Szolnoky G - - 2012
Lipedema is a disproportional obesity due to unknown pathomechanism. Its major hallmark is frequent hematoma formation related to increased capillary fragility and reduced venoarterial reflex. Beyond microangiopathy, both venous and lymphatic dysfunction have also been documented. However, arterial circulation in lipedema has not been examined, and therefore we explored aortic ...
Williams Bryan - - 2012
Arterial aging is associated with a progressive increase in aortic stiffening, which results in a rise in central aortic pressures. Traditionally, blood pressure (BP)-lowering therapy has been directed at brachial rather than central pressures. However, a key contemporary question is whether this strategy is optimal in reducing aortic pressure and ...
Sarazan R Dustan - - 2012
Increasing or decreasing cardiac contractility is an undesirable property of drugs being developed for noncardiovascular indications. The International Conference on Harmonization (ICH) Topic S7A and S7B guidelines only require the assessment of heart rate, blood pressure and the electrocardiogram in nonclinical in vivo safety pharmacology studies. Assessment of drug effects ...
Giridharan Guruprasad A - - 2012
Ventricular assist devices (VADs) have been used successfully as a bridge to transplant in heart failure patients by unloading ventricular volume and restoring the circulation. An artificial vasculature device (AVD) is being developed that may better facilitate myocardial recovery than VAD by controlling the afterload experienced by the native heart ...
Rubini Alessandro - - 2012
Context: Angiotensin stimulates smooth-muscle contraction. Accordingly, angiotensin-converting enzyme (ACE) inhibition is expected to decrease airway resistance. Objectives: To measure the effects of ACE inhibition on respiratory mechanics in healthy mammals. Materials and methods: We measured respiratory mechanics before and after i.p. ACE inhibitor captopril (100 mg/kg) in normal anaesthetised rats. The ...
Li Tao - - 2012
This paper describes a valve-regulated architecture for intrathecal, insulin and other drug delivery systems that offers high performance and volume efficiency through the use of micromachined components. Multi-drug protocols can be accommodated by using a valve manifold to modulate and mix drug flows from individual reservoirs. A piezoelectrically-actuated silicon microvalve ...
McCracken M J - - 2012
Reasons for performing study: Subjective evaluation of mild lameness has been shown to have poor interobserver reliability. Traditional methods of objective lameness evaluation require specialised conditions and equipment. Wireless inertial sensor systems have been developed to allow for simple, rapid, objective lameness detection in horses trotted over ground. Objective: The ...
Sternberg Zohara - - 2012
Multiple sclerosis (MS) is a disease with multiple etiologies. The most recent theory of the vascular etiology of MS, Chronic Cerebrospinal Venous Insufficiency (CCSVI), suggests that cerebral venous obstruction could lead to cerebral venous reflux, promoting local inflammatory processes. This review article offers strong evidence that the route of the ...
Parati Gianfranco - - 2012
Evidence assembled in this review indicates that sympathetic nervous system dysfunction is crucial in the development of heart failure and essential hypertension. This takes the form of persistent and adverse activation of sympathetic outflows to the heart and kidneys in both conditions. An important goal for clinical scientists is translation ...
Ward Gemma - - 2012
INTRODUCTION: The objective of this study was to evaluate the ability of a non-invasive telemetry monitoring system to detect and quantify changes in blood pressure and electrocardiogram (ECG) parameters in response to vehicle, l-NAME or minoxidil administration to freely moving beagle dogs. Data from a non-invasive telemetry monitoring system were ...
Chalmers E - - 2012
Bracing is a common non-surgical treatment for scoliosis, but its effectiveness has been debated. Some clinical studies have shown efficacy of brace treatment is correlated to how the brace has been worn. The more often the patients wear their braces to the prescribed tightness as well as the prescribed length ...
Ryska Ondrej - - 2012
Objectives: Extracorporeal liver support (ELS) may play a role in bridging therapy in patients with acute liver failure (ALF). The aim of this study was to compare the influence of nonbiological and biological methods on intracranial pressure (ICP) in an animal model of ALF. Methods: A surgical devascularization model of ...
Mitchell Greg W - - 2012
1. Determining how events interact across stages of the annual cycle is critical for understanding the factors that affect individual fitness. However, there is currently little information detailing how breeding events influence migratory behaviour. 2. Using an automated digital telemetry array and an isolated island-breeding population of Savannah sparrows Passerculus sandwichensis, we ...
Wong I K Y - - 2012
Objective: To compare interface pressure (IP) and static stiffness index (SSI) of four different compression systems currently in use for the treatment of patients with venous leg ulcer. Method: Fifty-two ambulatory adults with healthy legs were recruited at random at a study centre after they had consented. The evaluated systems ...
Sayorwan Winai - - 2012
Investigate the effects of lavender oil on the central nervous system, autonomic nervous system, and mood responses in humans after inhalation. Twenty healthy volunteers participated in the experiments. The present study assessed autonomic parameters such as blood pressure, heart rate, respiratory rate, and skin temperature to determine the arousal level ...
Chen Jie - - 2012
The role of the cerebral venous system (CVS) in intracranial pressure (ICP) regulation remains largely unclear. In the present study, the interaction between ICP and the cerebral venous system and its possible mechanism were investigated with respect to the biological characteristics of the cerebral venous system and its hemodynamic response ...
Liang Yang-Min - - 2012
A pressurized activated sludge reactor with a sand layer installed at the bottom of the reactor for filtration purposes was employed for treating synthetic organic wastewater. The intermittent high-pressure sequential bioreactor (IHPSB) was pressurized to facilitate efficient oxygen transfer under elevated biomass conditions with pressure released periodically, i.e. aeration, for ...
Parasuraman Subramani S Department of Pharmacology, Jawaharlal Institute of Postgradute Medical Education and Research, Pondicherry, - - 2012
Blood pressure (BP) is one of the vital parameters used to assess the cardiovascular functions of a mammal. BP is commonly recorded using invasive, noninvasive, and radio telemetry methods, but invasive blood pressure (IBP) recording is considered the gold standard. IBP provides a direct indication of the effect of the ...
Hentschel Roland - - 2012
OBJECTIVE:: To study appropriateness of respiratory system compliance calculation using an inflation hold and compare it with ventilator readouts of pressure and tidal volume as well as with measurement of compliance of the respiratory system with the single-breath-single-occlusion technique gained with a standard lung function measurement. DESIGN:: Prospective clinical trial. ...
Morato José B - - 2012
PURPOSE: Automated weaning modes are available in some mechanical ventilators, but no studies compared them hitherto. We compared the performance of 3 automated modes under standard and challenging situations. METHODS: We used a lung simulator to compare 3 automated modes, adaptive support ventilation (ASV), mandatory rate ventilation (MRV), and Smartcare, ...
Lindman Brian R - - 2012
Pressure overload resulting from aortic stenosis causes maladaptive ventricular and vascular remodeling that can lead to pulmonary hypertension, heart failure symptoms, and adverse outcomes. Retarding or reversing this maladaptive remodeling and its unfavorable hemodynamic consequences has the potential to improve morbidity and mortality. Preclinical models of pressure overload have shown ...
Montezano Augusto C - - 2012
Many factors have been implicated in the pathophysiology of hypertension such as upregulation of the renin-angiotensin-aldosterone system, activation of the sympathetic nervous system, perturbed G protein-coupled receptor signalling, inflammation, and altered T-cell function. Common to these processes is increased bioavailability of reactive oxygen species (ROS) (termed oxidative stress) due to ...
Osgood Michael J MJ Department of Surgery, Vanderbilt University Medical Center, Nashville, TN 37232-0011, USA. - - 2012
The saphenous vein remains the most widely used conduit for peripheral and coronary revascularization despite a high rate of vein graft failure. The most common cause of vein graft failure is intimal hyperplasia. No agents have been proven to be successful for the prevention of intimal hyperplasia in human subjects. ...
Wu Jian - - 2012
Elevation of left ventricular end-systolic pressure (LVESP) and hypertrophic response in mice varies after transverse aorta constriction (TAC). Micromanometric catheterization, conventionally used to select mice with successful TAC, is invasive and nonreusable. We aimed to establish noninvasive imaging protocols for early estimation of successful TAC by ultrasound biomicroscopy (UBM). Out ...
Vorob'ev Vladimir Sergeevich - - 2012
We apply the new scaling relations and global isomorphism between continuous and discrete systems to find of saturation pressure. On this basis we obtain the expression for the saturation pressure containing the critical, Z line parameters and two fitting parameters. First we calculate the saturation pressure for a number of ...
Georgakarakos Efstratios - - 2012
The isolation of the aneurysm sac from systemic pressure and its consequent shrinkage are considered criteria of success after endovascular repair (EVAR). However, the process of shrinkage does not solely depend on the intrasac pressure, the predictive role of which remains ambiguous. This brief review summarizes the additional pathophysiological mechanisms ...
García Anmi - - 2012
We propose an experimental efficient optical pressure sensor based on a variable liquid lens and a modified point diffraction interferometer. The working principle of the sensor is based on the fact that a variation in pressure induces a change in lens curvature and hence in its focal length, which can ...
Martinewski Alexandre - - 2012
We performed the initial assessment of an alternative pressurized intraventilated (PIV) caging system for laboratory mice that uses direct-current microfans to achieve cage pressurization and ventilation. Twenty-nine pairs of female SPF BALB/c mice were used, with 19 experimental pairs kept in PIV cages and 10 control pairs kept in regular ...
Rey Markus - - 2012
Here we evaluated the ability of a new, dual blood-pressure telemetry transmitter to simultaneously measure pulmonary and systemic blood pressure and the electrocardiogram in rats. The transmitter was implanted in normotensive and monocrotaline-induced pulmonary hypertensive Wistar rats, with sensing catheters placed in the pulmonary artery (channel 1) and descending aorta ...
Kohsaka Akira - - 2012
Understanding how the 24-hour blood-pressure rhythm is programmed has been one of the most challenging questions in cardiovascular research. The 24-hour blood-pressure rhythm is primarily driven by the circadian clock system, in which the master circadian pacemaker within the suprachiasmatic nuclei of the hypothalamus is first entrained to the light/dark ...
< 2 3 4 5 6 7 8 9 10 11 12 >