Search Results
Results 151 - 200 of 1908
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Masuda Noriyuki - - 2008
AIMS: The role of I(h) channels at the spinal level in the control of bladder function was examined in urethane anesthetized female rats. METHODS: Bladder activity was recorded via a transurethral catheter under isovolumetric conditions or via an intravesical catheter during continuous infusion cystometry. ZD7288, a selective I(h) channel inhibitor, ...
Singh S K - - 2008
AIMS: Intrathecal and epidural administration of micro-agonist opioids is associated with urinary retention, a potentially serious adverse-event. In animal studies tramadol has been found not to affect voiding function. We evaluated urodynamic effects of epidural tramadol in humans. METHODS: Fifteen adults planned for cystoscopy under local-anesthesia underwent urodynamics (UDS) at ...
Serpytis Mindaugas - - 2008
OBJECTIVE: The objectives of this study were to determine the incidence of intra-abdominal hypertension in patients after major abdominal surgery and to evaluate the correlation of intra-abdominal pressure with fluid balance and systemic inflammatory response syndrome. MATERIAL AND METHODS: This is a prospective observational study. Patients, admitted to intensive care ...
Ichino Midori - - 2008
AIMS: To disclose the nature of the high-pressure voiding observed in small boys and to determine the influence of a transurethral catheter on voiding urodynamic parameters and reproducibility of these parameters. MATERIALS AND METHODS: Video-urodynamic studies (V-UDSs) were repeated twice in a single session using two different sized, 18G (Ø1.15 ...
Moslavac S - - 2008
AIMS: To compare leak-point intravesical pressure and cystometric capacity in complete and incomplete spinal cord injury (SCI) patients with neurogenic detrusor overactivity (NDO). METHODS: Retrospective study of filling cystometry at non-physiological filling rate in 80 SCI patients at rehabilitation or annual check-up using Dantec Etude urodynamic machine. RESULTS: Fifty neurologically ...
Lee Sang Wook - - 2008
AIMS: Natural bladder filling by the production of urine could potentially influence the outcome of urodynamic investigations. In this prospective study, we determined the natural bladder filling rate during cystometry. METHODS: Between October 2005 and March 2006, we performed conventional urodynamic studies in 101 consecutive patients. We measured the exact ...
Klarskov Niels - - 2008
AIMS: The mechanism of action of injection therapy is virtually unknown. Urethral Pressure Reflectometry (UPR) is a novel technique for measuring pressure and cross-sectional area in the urethra. UPR which provides reliable physiological meaningful parameters was used to study the mechanism of urethral injection therapy. MATERIALS AND METHODS: Fifteen patients ...
Rosario Derek J - - 2008
AIMS: Clinical nomograms for differentiating obstructed from unobstructed voiding and poor detrusor contractility from normal contractility have traditionally been drawn on the basis of symptomatic response to outflow tract surgery or on urodynamic changes in men with LUTS before and after surgery. The aim of this study was to examine ...
Kefer John C JC Glickman Urological Institute, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio, - - 2008
We hypothesized that transection of the pubo-urethral ligament in the female rat would cause stress urinary incontinence, as indicated by decreased leak point pressure. We created a novel model of pubo-urethral ligament deficiency in the rat and validated our model through comparison with an established model of stress urinary incontinence. ...
Dalfino Lidia - - 2008
OBJECTIVE: To investigate the relationship between intra-abdominal hypertension (IAH) and acute renal failure (ARF) in critically ill patients. DESIGN AND SETTING: Prospective, observational study in a general intensive care unit. PATIENTS: Patients consecutively admitted for >24 h during a 6-month period. INTERVENTIONS: None. MEASUREMENTS AND RESULTS: Intra-abdominal pressure (IAP) was ...
Malbrain Manu L N G - - 2008
OBJECTIVE: Intra-abdominal pressure (IAP) measurement is important in daily clinical practice. Most measurement techniques vary in automaticity and reproducibility. This study tested a new fully automated continuous technique for IAP measurement, the CiMON. METHODS: Three IAP measurement catheters (a Foley manometer and two balloon-tipped catheters) contained in a 50-ml infusion ...
Wallis M Chad - - 2007
We have devised a bioreactor to simulate normal urinary bladder dynamics. The design permits a cell-seeded scaffold made from a modified porcine acellular matrix to be placed between 2 closed chambers filled with culture medium and be mechanically stimulated in a physiologically relevant manner. Specifically designed software increased hydrostatic pressure ...
Shafik Ahmed - - 2008
BACKGROUND/AIM: We investigated the hypothesis that external (EUS) and internal (IUS) urethral sphincters and urinary bladder (UB) respond to penile thrusting (PT) of vagina in a way that prevents urinary leakage during coitus. METHODS: Vaginal condom was inflated with air in increments of 50-300 ml and EMG of EUS and ...
Keqin Zhang - - 2007
OBJECTIVES: We evaluated a noninvasive method to predict bladder outlet obstruction (BOO) and bladder function in patients with benign prostatic enlargement (BPE) based on intravesical prostatic protrusion (IPP) using transabdominal ultrasound. METHODS: The records of 206 first-visit patients with BPE were reviewed. We divided patients into two groups based on ...
Pistolesi Donatella - - 2007
Elevated intra-abdominal pressure has been recognized as a cause of significant morbidity and mortality in critically ill patients, exerting a considerable impact on organ function. Early detection and adequate treatment have been identified as essential measures to prevent the development of abdominal compartment syndrome. We present a case of early ...
Yoshida Masaki - - 2007
Silodosin is a novel selective alpha(1A)-adrenoceptor (AR) antagonist generated by Kissei Pharmaceutical Co. Ltd. This drug selectively binds to alpha(1A)-AR, which is widely distributed in the prostate, urethra and bladder trigone, involved in their contraction, located at the lower urinary tract. This high selectivity for alpha(1A)-AR contributes to inhibition of ...
Noguchi Yukiko - - 2008
Alpha-adrenoceptor antagonists are used worldwide for the treatment of voiding dysfunction associated with benign prostatic hyperplasia. Recently, abnormal ejaculation, an adverse effect associated with their use, has attracted attention. Here, we simultaneously investigated the effects of alpha(1)-adrenoceptor antagonists on intraurethral pressure in the prostatic urethra and intraluminal pressure in the ...
Liao Li-Min - - 2007
AIM: To evaluate the effects of retrospective quality control on pressure-flow data with computer-based urodynamic systems from men with benign prostatic hyperplasia (BPH). METHODS: A total of 582 traces of pressure-flow study from 181 men with BPH was included in the study. For each trace, maximum urinary flow rate (Q(max)) ...
Hoh Ivan M Y - - 2007
OBJECTIVE: To examine the relevance of bladder volume in patients with chronic hydronephrosis and abnormal bladder function who lose renal function even though the bladder or reservoir pressure is normal (<40 cmH(2)0). PATIENTS AND METHODS: In all, 20 patients (16 male; age range 17-67 years) were studied prospectively; 12 had ...
Salas Juan Carlos Toledo - - 2008
The cholinergic neurons in the laterodorsal tegmental nucleus (LDT) play a crucial role in the regulation of rapid eye movement (REM) sleep. Because penile erection occurs during REM sleep, the involvement of the LDT in penile erection was examined in unanesthetized head-restrained rats. To detect penile erection, corpus spongiosum of ...
Ichino Midori - - 2007
PURPOSE: We sought to determine the etiology of high pressure voiding in male infants, and to clarify the mechanisms of its improvement with maturation. MATERIALS AND METHODS: We retrospectively reviewed 106 videourodynamic studies obtained from 78 male infants with either congenital renal abnormalities or episodes of urinary tract infection, without ...
Peng Qiyu - - 2007
Clinically the strength of the contraction of the female pelvic floor is qualitatively evaluated by vaginal tactile palpation. We therefore developed a probe to enable the quantitative evaluation of the closure pressures along the vagina. Four force sensors mounted on the four orthogonal directions of an intra-vaginal probe were used ...
Hsiao Sheng-Mou - - 2008
The objective of this study was to sequentially compare the urodynamic findings of patients with urodynamic stress incontinence before and after transobturator tape procedure. Between May 2004 and December 2005, 26 of 34 consecutive patients with urodynamic stress incontinence who underwent transobturator tape procedure were enrolled. The sequential urodynamic findings ...
Kang Kyung K - - 2007
AIM: This study was performed to investigate the effect of DA-8159, a selective phosphodiesterase 5 (PDE5) inhibitor, on benign prostatic hyperplasia (BPH) both in vitro and in vivo. METHODS: We assessed the influence of DA-8159 on the contractility of rat prostate tissues in an organ-bath experiment. In addition, in order ...
Shafik Ahmed - - 2007
BACKGROUND: We investigated the hypothesis that urethral stimulation effects vesical contraction. METHODS: Vesical pressure response to urethral balloon distension with normal saline in increments of 1 mL was recorded in 26 healthy volunteers (17 men, 9 women; mean age, 36.9 +/- 9.7 SD years) before and after individual anesthetization of ...
Yokoyama Osamu - - 2007
PURPOSE: Antimuscarinic drugs increase bladder capacity without prominent side effects such as urinary retention even when administered to patients with mild to moderate bladder outlet obstruction. Some mechanisms might exist in the urethra to compensate for the emptying function of the detrusor after the administration of antimuscarinic drugs. We investigated ...
Gacci Mauro - - 2007
PURPOSE: We assessed urodynamic changes after vardenafil administration in spinal cord injured male patients on oxybutynin treatment. MATERIALS AND METHODS: We performed a single center, randomized, double-blind, placebo controlled trial in 25 patients with spinal cord injury who had erectile dysfunction and micturition disorders. A baseline urodynamic test was performed ...
Jung H U - - 2008
OBJECTIVE: Recently, we showed that endoluminally administered isoproterenol (ISO) inhibits muscle function of the pyeloureter in swine. This may be of value in managing increases in pelvic pressure during upper urinary tract endoscopy. The purpose of this study was to examine the effect of endoluminally administered ISO on increases in ...
Lonardo M - - 2007
AIM: The aim of this study was to assess the prevalence of intra-abdominal hypertension and its prognostic value in critical patients. METHODS: In an observational study, 56 patients of a multidisciplinary intensive care unit (ICU) of a university hospital, with either surgical (44.6%) or medical (55.4%) diagnoses, were studied. Intra-abdominal ...
Benninger Emanuel - - 2008
BACKGROUND: To compare volume reserve capacity (VRC) and development of intra-abdominal hypertension after different in vitro temporary abdominal closure (TAC) techniques. METHODS: A model of the abdomen was designed. The abdominal wall was simulated with polychloroprene, a synthetic rubber compound. A lentil-shaped defect of 150 cm(2) was cut into the ...
Scheepe Jeroen R - - 2007
PURPOSE: Oxybutynin is used clinically to lower intravesical pressure and detrusor overactivity. In vitro it inhibits stretch induced bladder smooth muscle cell proliferation. We tested whether oxybutynin also prevents hypertrophic bladder changes in vivo in a model of partial bladder obstruction. MATERIALS AND METHODS: Subvesical obstruction was induced in immature ...
Almodhen Fayez - - 2007
PURPOSE: We examined the urodynamic and upper urinary tract changes in children with myelomeningocele treated conservatively through puberty at our institution between 1980 and 2006. MATERIALS AND METHODS: A total of 40 patients were exclusively treated conservatively with or without anticholinergics and/or clean intermittent catheterization through puberty at our institution. ...
Cassu Renata N - - 2008
OBJECTIVE: To compare the analgesic effect of uni- and bi-lateral electroacupuncture (EA) in response to thermal and mechanical nociceptive stimuli and to investigate the cardiorespiratory, endocrine, and behavioral changes in dogs submitted to EA. STUDY DESIGN: Prospective, randomized cross-over experimental study. ANIMALS: Eight adult, clinically healthy, cross-breed dogs, weighing 13 ...
Huwyler Mirjam - - 2007
The aim of this project was to evaluate the ice-water test as a predictor of the response to intradetrusor botulinum toxin injection in patients with neurogenic detrusor overactivity. We retrospectively evaluated the urodynamic parameters in 22 patients with neurogenic bladder dysfunction and positive ice-water test. Maximum cystometric capacity (MCC), reflex ...
Zhang Wei-Fang - - 2007
BACKGROUND: Severe acute pancreatitis (SAP) is a serious disease with many complications, high mortality and poor prognosis. It is characterized by rapid deterioration and poses one of the most difficult challenges in clinical practice. Previous investigations suggest that SAP is one of the main causes of intra-abdominal pressure (IAP) increase. ...
Sugaya Kimio - - 2007
This study was undertaken to examine the role of the afferent and efferent pathways of the lumbosacral spinal nerve roots in the tonic control of bladder activity. Changes of isovolumetric bladder activity were recorded in 21 sympathectomized female rats under urethane anesthesia following transection of the dorsal (DRT) and ventral ...
Kessler Thomas M - - 2008
OBJECTIVE: The precise mechanisms underlying cerebral regulation of lower urinary tract function are still poorly understood. In patients with disabling essential tremor (ET) refractory to pharmacotherapy, thalamic deep brain stimulation (DBS) is an effective treatment for tremor control. Here, we evaluated the effect of thalamic DBS on urodynamic parameters in ...
Sajeel Mustafa - - 2007
PURPOSE: We determined whether categorizing men with lower urinary tract symptoms using a noninvasive pressure flow nomogram is sensitive to change following the removal of obstruction. MATERIALS AND METHODS: A prospective cohort of men undergoing transurethral prostate resection was recruited, of whom 143 (69%) underwent noninvasive pressure flow study using ...
Julia-Guilloteau V - - 2007
During stress-induced increase in abdominal pressure, urinary continence is maintained by urethral closure mechanisms. Active urethral response has been studied in dogs and rats. Such an active urethral response is also believed to occur in humans during stress events. We aimed to investigate urethral closure mechanisms during sneezing in cats. ...
Kamo Izumi - - 2007
A novel method for evaluating the urethral resistance during abrupt elevation of abdominal pressure was developed in spinalized female rats under urethane anesthesia. Electrical stimulation of abdominal muscles for 1 s induced increases in both the intra-abdominal and the intravesical pressure in a stimulus-dependent manner, and the bladder response was ...
Kuhn Annette - - 2008
OBJECTIVE: Aim of the study was to correlate urethral retro resistance pressure with the maximum urethral closure pressure (MUCP) and functional urethral length (FUL) in patients with urinary incontinence and healthy individuals. STUDY DESIGN: Two hundred and twenty patients with the complaint of urinary incontinence had a urodynamic examination including ...
Hansen John - - 2007
The aim of this study was to investigate the feasibility of using external urethral sphincter electromyogram (EMG) (EUSEMG) to detect the onset of detrusor contractions in patients with both neurogenic detrusor overactivity (NDO) and detrusor sphincter dyssynergia (DSD). Detrusor pressure (Pdet) and EUSEMG was recorded in 23 neurogenic patients during ...
Shaw Matthew B - - 2007
OBJECTIVE: To present a novel porcine model of bladder outlet obstruction (BOO) with a standardized bladder outlet resistance and real-time ambulatory radio-telemetered cystometry, as BOO is a common condition with many causes in both adults and children, with significant morbidity and occasional mortality, but attempts to model this condition in ...
De Laet Inneke - - 2007
OBJECTIVE: The objective was to prospectively study the effect of neuromuscular blockers on intra-abdominal pressure (IAP) and a number of physiological variables in patients with increased IAP. DESIGN: Prospective cohort study. SETTING: Intensive care unit of the Ghent University Hospital. PATIENTS AND PARTICIPANTS: Ten critically ill patients with intra-abdominal hypertension ...
Akkad Thomas - - 2007
OBJECTIVES: To assess the influence of intravesical potassium on pelvic floor activity (PFA) during voiding in women with symptoms of overactive bladder (OAB), by using comparative urodynamics (CUD). PATIENTS AND METHODS: The study included 175 women who met the criteria of OAB (mean age 52.7 years, range 18-87). CUD included ...
Idzenga Tim - - 2007
In patient studies the correlation between maximum urethral closure pressure (MUCP) and Valsalva leak point pressure (LPP) is meagre at best (r = 0.22-0.50). We therefore studied the relation between MUCP and LPP in a flexible and extensible model urethra. We applied differently sized pressure zones and different degrees of ...
Naruganahalli Krishna S - - 2007
The aim of this study was to describe a new experimental animal model for simultaneous measurement of carbachol-induced increase in intravesical pressure and salivary secretion in rabbits. Further, we also compared the in vivo potency and urinary bladder versus salivary gland selectivity profiles of Oxybutynin, Tolterodine, Solifenacin and Darifenacin. The ...
Duckett R A Jonathan - - 2008
This study was to assess the effect of spinal anaesthesia on urethral retro-resistance pressure (URP), cough pressures and tendency to leak. The population consisted of 32 women undergoing a tension-free vaginal tape (TVT) operation under a spinal anaesthetic. URP, cough pressures and an assessment of the degree of leak were ...
Stover Joshua - - 2007
Previous studies demonstrated that the bladder exhibited severe tissue remodeling following spinal cord injury. In such pathological bladders, uninhibited non-voiding contractions subject bladder cells to cyclic oscillations of intravesical pressure. We hypothesize that cyclic pressure is a potential trigger for tissue remodeling in overactive bladder. Using a custom-made setup, rat ...
Mitterberger Michael - - 2007
OBJECTIVE: Transurethral ultrasound-guided injection of autologous myoblasts has recently been shown to cure urinary stress incontinence. In the present study, the dose-dependent changes in maximal urethral closure pressures after application of myoblasts were investigated in a porcine animal model. METHODS: Myoblast cultures were grown from a porcine muscle biopsy. The ...
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