Search Results
Results 401 - 450 of 1336
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Stabouli Stella - - 2005
OBJECTIVES: To investigate 24-hour ambulatory blood pressure, lipid profiles, and carotid artery intimal-medial thickness (IMT) in adolescents with and without obesity. STUDY DESIGN: Ambulatory blood pressure data from 93 consecutive adolescents referred to our hypertension center for possible hypertension were analyzed. Fasting serum glucose and lipid concentrations were measured in ...
Arfvidsson Berndt - - 2005
Clinically, it has been observed that severely and morbidly obese individuals more often have venous leg symptoms related to venous stasis than normal-weight persons have. Obesity is associated with an increased intraabdominal pressure (IAP). The increased IAP in severely and morbidly obese patients would reasonably cause an elevated iliofemoral venous ...
Lambert David M - - 2005
BACKGROUND: Recent data suggests that increased intra-abdominal pressure (IAP) is one factor associated with the morbidity of morbidly obese patients, who have a BMI>35 kg/m2. IAP has been proposed to be an abdominal compartment syndrome (ACS). This study investigated the characteristics of IAP in morbidly obese patients. METHODS: 45 morbidly ...
Ravisankar P - - 2005
In the present study, we investigated the correlation between body mass index (BMI), blood pressure (BP) indices and indices of physical fitness in apparently healthy subjects aged 14-18 years. We obtained data from 145 (105 males and 40 females) and assessed the correlation between BMI, and heart rate, systolic pressure ...
Couch Sarah C - - 2005
PURPOSE OF REVIEW: The prevalence of hypertension among children in the US is increasing in concert with rising obesity rates. Leading health organizations agree that elevated blood pressure should be managed in children; however, data on the relation between diet and lifestyle and blood pressure in this age group are ...
Mukherjee Ratnakar - - 2005
Leptin is a recently isolated circulating peptide hormone that is primarily synthesized and secreted by adipocytes. One of the major functions of this hormone is the control of energy balance by binding to receptors in the hypothalamus, leading to reduction in food intake, elevation in temperature and energy expenditure. In ...
Reinehr Thomas - - 2005
OBJECTIVE: It has been questioned whether insulin resistance or obesity is the central abnormality contributing to the cardiovascular risk factors dyslipidemia and hypertension in obesity. RESEARCH METHODS AND PROCEDURES: We studied weight status [SD score (SDS)-BMI], lipids (triglycerides, low-density lipoprotein- and high-density lipoprotein-cholesterol), blood pressure, and insulin resistance index [as ...
Schneider Rosa - - 2005
BACKGROUND: Obesity is characterized by insulin resistance and hyperinsulinemia that may elevate arterial pressure due to sympathetic overactivity and volume overload. The aim of the study is to measure hemodynamic parameters and metabolic variables in obese normotensive subjects. METHODS: Twenty-four normotensive, overweight subjects from our medical staff were enrolled. They ...
Kraja Aldi T - - 2005
Genome-wide variance components linkage analysis was performed on 4 latent factors underlying metabolic syndrome derived from 10 risk factors. The latent factors represent obesity and insulin, blood pressure, lipids and insulin, and central obesity. The metabolic syndrome factor scores were derived in 4 ethnic groups recruited in 3 Networks of ...
Weitz G - - 2005
The association between low birth weight (LBW) and elevated blood pressure has been attributed to disturbances in the endocrine and sympathetic nervous system. The present study focussed on parameters of cardiovascular and sympathetic function and on adrenocortical activity in 24 healthy subjects aged 20 - 30 years with a birth ...
Bergvall Niklas - - 2005
BACKGROUND: Although an inverse association between size at birth and blood pressure has been found in several studies, few studies have adjusted for the influence of socioeconomic and familial effects. METHODS: We investigated whether the association between birth weight and systolic blood pressure in young men is confounded by socioeconomic ...
Gaciong Z - - 2005
This study aims to determine the efficacy and tolerability of sibutramine hydrochloride in overweight and obese patients with cardiovascular risk factors. This was a 12-week, open-label, observational trial carried out in primary care settings. Patients' data were obtained from questionnaires received from 153 physicians. A total of 2225 overweight and ...
Fuchs Flávio D - - 2005
OBJECTIVE: To investigate the association between several anthropometric measurements of obesity with the incidence of hypertension. RESEARCH METHODS AND PROCEDURES: Participants were 592 individuals free of hypertension, selected at random from the community. In the baseline evaluation, they were submitted to completed measures of demographics, anthropometrics, blood pressure, and other ...
Ashrafi M R - - 2005
To obtain blood pressure distribution for Iranian children, we assessed 10,288 students aged 6-13 years (4871 boys and 5417 girls) in Tehran. Mean systolic and diastolic blood pressure showed incremental increases with age, weight and height in both sexes. Mean increases in systolic blood pressure for boys and girls were ...
Reinehr Thomas - - 2005
To confirm the existence of obesity-induced inflammation and to clarify the association between such inflammation and other cardiovascular risk factors, we investigated the relationships between high-sensitive C-reactive protein (hsCRP), tumor necrosis factor alpha (TNF-alpha), obesity, blood pressure, lipids, and insulin resistance in a long-term follow-up of obese children. We compared ...
Lotti Pamela - - 2005
To our knowledge no data have been reported on the contribution to acute increase in dyspnea by the respiratory muscles in obese nonsmoking subjects. To better focus on this topic, we studied seven obese subjects and an age-matched normal control group, assessing baseline pulmonary function, breathing pattern, esophageal pressure (Pes), ...
Hardy Rebecca R Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, UK. - - 2006
It has been suggested that the association between birthweight and blood pressure has been overstated as a result of publication bias and, within studies, a lack of adjustment for potentially important maternal and socioeconomic confounding factors and 'overadjustment' for current body size. This study investigates the impact of potential confounding ...
Morris Margaret J - - 2005
Obesity induced by a high-fat diet was associated with increased tail-cuff blood pressure in adult rats. The mechanisms underlying obesity-related hypertension are unclear, but increased sympathetic activation most probably plays a role. Neuroendocrine alterations observed in obesity may influence both feeding patterns and blood pressure. Work from our laboratory has ...
Haynes William G - - 2005
Obesity in humans causes hypertension, myocardial hypertrophy and coronary atherosclerosis, and increased cardiovascular morbidity and mortality that is thought to be related to sympathetic overactivity. Leptin is an adipocyte-derived hormone that acts in the hypothalamus to regulate appetite, energy expenditure and sympathetic nervous system outflow. One of the major mechanisms ...
Eikelis Nina - - 2005
Earlier ideas that sympathetic nervous system activity is low in human obesity, contributing to weight gain through absence of sympathetically mediated thermogenesis, can now be discounted. The application of sympathetic nerve recording techniques and isotope dilution methodology quantifying neurotransmitter release from sympathetic nerves has established that the sympathetic outflows to ...
Kawada Tomoyuki - - 2005
Self-report data were compared with actual recorded data on height, weight, and blood pressure during health examinations to check for validity. The subjects were 1,823 persons, ages 40-68 years. Pearson correlations for systolic blood pressure, diastolic blood pressure, height, weight, and Body Mass Index between data reported in 1993 and ...
Randall Otelio S - - 2005
Blood pressure is a major risk factor for cardiovascular events, although the role of pulse pressure, an independent predictor of arterial stiffness, has recently been emphasized. This study examines the baseline relationship between body mass index (BMI) and blood pressure indexes in 215 obese African Americans enrolled in a diet-exercise ...
Schunkert H - - 2005
The MONICA/KORA surveys are characterized by a careful and broad investigation of multiple cardiovascular phenotypes. Particularly, repeated blinded measurements of blood pressure, comprehensive echocardiographic and electrocardiographic evaluations as well as differentiation between fat and fat-free body mass have led to manifold innovative observations. Specifically, genetic and serological markers of the ...
Schutte R - - 2005
High leptin levels are often observed in human obesity and are implicated in obesity-related hypertension. Leptin levels have been found to be higher in hypertensive obese African-American women compared to normotensive African-American women, but a direct association between leptin and blood pressure could not be obtained. Additionally, increased adiposity has ...
Broyd Christopher - - 2005
OBJECTIVE: An association between birth weight and blood pressure has been reported in many studies, but the strength of this association has been disputed. Birth weight could, however, be associated with alterations in the proximal arterial tree that have little effect on blood pressure. The objective of this study was ...
Phillips David I W - - 2005
We tested the hypothesis that women who are thin or have poor pregnancy weight gain have offspring with higher blood pressure and examined whether this link is mediated by increased secretion of cortisol. We studied a cohort of 388 children born in Kingston, Jamaica. From hospital records we obtained information ...
Morse Stephen A - - 2005
There is growing recognition that obesity is reaching epidemic proportions throughout the world. In adults, obesity is associated with increased cardiovascular morbidity and mortality. A series of endocrine, metabolic and hemodynamic mechanisms have been responsible for the development of obesity-hypertension. These mechanisms include: a suppressed biologic activity and availability of ...
Mikkelsson L - - 2005
The aim was to study whether aerobic fitness measured by a maximal endurance running test at adolescence predicts prevalence of hypertension or blood pressure levels in adulthood. From the 413 (197 slow runners and 216 fast runners) participating in a 2000-meter running test at adolescence in 1976 and responding to ...
Yalcin Bektas Murat - - 2005
BACKGROUND: Epidemiological studies find a progressive increase in the prevalence of elevated blood pressure with increasing adipose tissue. But there is no common opinion about which effectiveness of the anthropometric measurement tools indicating general or android obesity are most important to follow up in patients with elevated blood pressures. OBJECTIVES: ...
Lawlor D A - - 2005
AIMS: To assess the associations of type and duration of infant feeding with components of the metabolic syndrome in children aged 9 and 15. METHODS: A total of 2192 randomly selected schoolchildren aged 9 and 15 years from Estonia (n = 1174) and Denmark (n = 1018) were studied. Insulin ...
Adami Gianfranco - - 2005
BACKGROUND: The weight loss surgically induced by gastroplasty or gastric banding has only a transitory effect on the arterial hypertension of the severely obese patients, and a prevalence of hypertension similar to that of controls has been reported 8 years after the operation. METHODS: We studied the effects of biliopancreatic ...
Koupil Ilona - - 2005
OBJECTIVE: It had been suggested that programming of the hypothalamo-pituitary-adrenal axis may underlie the associations of reduced size at birth with raised blood pressure in later life. We investigated whether morning salivary cortisol mediates the inverse association of birthweight with systolic blood pressure in children. DESIGN: Subjects and measurements--a historical ...
Kyle Ursula G - - 2006
STUDY OBJECTIVE: To evaluate the contribution of body composition measurements to clinical assessment in patients on home nasal positive-pressure ventilation for chronic hypercapnic respiratory failure (CHRF), and their relationship to respiratory impairment. METHODS: Patients with CHRF (restrictive lung disease (RLD), n=37; chronic obstructive pulmonary disease (COPD), n=19), during elective yearly ...
Aucott Lorna - - 2005
Many studies have assessed short-term effects of weight loss on blood pressure, whereas little attention has been paid to long-term effects. We conducted a systematic review to evaluate the long-term effects of weight loss on hypertension outcome measures in adults using literature published from 1966 to 2001. All prospective studies ...
Mamun Abdullah A - - 2005
Weight reduction in clinical populations of severely obese children has been shown to have beneficial effects on blood pressure, but little is known about the effect of weight gain among children in the general population. This study compares the mean blood pressure at 14 years of age with the change ...
Kaditis Athanasios G - - 2005
Higher or similar systolic and/or diastolic blood pressure has been recorded in children with sleep apnea compared to subjects with primary snoring or in those with primary snoring compared to controls. To investigate the association between blood pressure and habitual snoring, we studied children in four randomly selected schools in ...
Lawlor Debbie A - - 2005
PURPOSE OF REVIEW: While treating high blood pressure in middle age is beneficial in terms of reducing the occurrence of cardiovascular disease, treated and well controlled hypertensive adults still have a substantial excess mortality and reduced survival compared with normotensives. Therefore, identification of the means of preventing hypertension in earlier ...
Guízar Juan-Manuel - - 2005
We compared factors associated with sympathetic cardiac activity in 70 male adolescents (34 obese and 36 with appropriate weight). In fasting we measured insulin, leptin, glucose, blood pressure, and heart rate variability by power spectral analysis. Obese adolescents had higher values for systolic blood pressure, insulin, leptin, low frequency/high frequency ...
Rostand Stephen G - - 2005
BACKGROUND: Foetal growth retardation (FGR), defined as less than the 10th percentile of birth weight for gestational age, is reported to be an important contributor to hypertension and cardiovascular disease in children and adults, but findings are not consistent. For this reason we re-examined the role of FGR in childhood ...
Amador N - - 2005
Obesity has been shown to be associated with increased left ventricular mass (LVM) and heart sympathetic activity even in nonhypertensive subjects. These factors are predictors of cardiovascular morbidity and mortality independent of other traditional risk factors. We evaluated the effect of losartan and spironolactone on LVM and heart sympathetic activity ...
de Simone Giovanni - - 2005
BACKGROUND: We have shown that increased cardiac output is related to both fat-free mass and fat mass in obesity. OBJECTIVE: We studied the association of body fat distribution and body composition with flow-resistance relations in overweight. DESIGN: We studied 521 overweight, nonobese participants in the Hypertension Genetic Epidemiology Network (HyperGEN) ...
Nichols S D - - 2005
Fetal growth retardation has been linked to elevated blood pressure in adult life. This association between birth weight and blood pressure is present in childhood and is amplified with age. However, the mechanisms that underlie this association are largely unknown. We examined the relationship between birth weight and forearm vascular ...
van de Putte E M - - 2005
OBJECTIVES: To investigate whether constitutional laxity of the connective tissues is more frequently present in adolescents with chronic fatigue syndrome (CFS) than in healthy controls. Increased joint hypermobility in patients with CFS has been previously described, as has lower blood pressure in fatigued individuals, which raises the question of whether ...
Jafar Tazeen H - - 2005
BACKGROUND: Blood pressure during childhood is an established predictor of adult blood pressure, which in turn increases mortality as a result of cardiovascular disease. Adult South Asian populations are particularly predisposed to cardiovascular disease compared with whites, but the prevalence of high blood pressure and determinants of blood pressure in ...
Kwagyan John - - 2005
OBJECTIVE: Pulse pressure, a marker of arterial vascular properties, has been linked to cardiovascular diseases and complications. This study examined the impact of excess body mass and cardiovascular disease risk factors on pulse pressure (PP). DESIGN: Cross-sectional and prospective study. METHODS: Baseline data consist of 219 obese African Americans, with ...
Doggrell S A - - 2005
The association between obesity and hypertension is well known. The hemodynamic features of obesity-related hypertension are an expansion of extracellular volume inducing hypervolaemia and increased cardiac output, with activation of both the sympathetic nervous system and the renin--angiotensin system. It is suggested that obesity-related hypertension may be considered as a ...
Kotsis Vasilios - - 2005
The purpose of the present study was to determine the relationship between body mass index (BMI) and parameters derived from 24-hour ambulatory blood pressure monitoring including mean 24-hour daytime and nighttime systolic and diastolic blood pressures, 24-hour daytime and nighttime pulse pressure, mean 24-hour daytime and nighttime heart rate, dipping ...
de Simone Giovanni - - 2005
Abnormalities in whole blood viscosity (WBV) have been implicated in hypertension. This study analyzes relations between WBV and blood pressure in the Strong Heart Study population of American Indians. We examined 676 participants (489 women, age 62+/-7 years) without prevalent cardiovascular disease or use of antihypertensive medications, digoxin, or aspirin. ...
Adami Gian Franco - - 2005
Hypertension is a medical disorder frequently associated with severe obesity, and the effect of weight loss on the reduction of blood pressure has been well established. In this study, the relationships between the weight loss surgically obtained by biliopancreatic diversion and blood pressure were investigated in a population of severely ...
Cornelissen Véronique A - - 2005
OBJECTIVE: To assess the influence of resistance training on resting blood pressure in healthy sedentary adults. METHODS: A comprehensive literature search with the MEDLINE computerized database was conducted and reference lists of published articles and reviews on the topic were checked. Inclusion criteria were as follows: the study involved a ...
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