Search Results
Results 201 - 250 of 1338
< 1 2 3 4 5 6 7 8 9 10 >
Saha Indranil - - 2008
To find out the factors responsible for variations of adolescent blood pressure, a community-based cross-sectional study was undertaken among 1081 adolescents, aged 10-19 years, selected by simple random sampling in an urban slum of Kolkata, Chetla in 2003-04. Age, educational status, additional ghee/butter intake with diet, family history of hypertension, ...
Martin T C - - 2008
Increased left ventricular mass (LVM) on echocardiogram is an independent risk factor for cardiac complications from hypertension. It is associated with a four-fold increase in untoward cardiac events when present. Data were reviewed for 100 treated hypertensive Afro-Caribbean patients, aged 29 to 65 years, recruited from village health clinics. Age, ...
Morimoto Aya - - 2008
Tsunan, Niigata is a non-westernized rural Japanese town, known for heavy snowfalls and as a rice-producing area, whose inhabitants have a long life expectancy. We investigated the prevalence of obesity, metabolic syndrome (MetS) and its components in Tsunan. A total of 1,155 men and women, 40-69 years of age were ...
Sabatier Manning J - - 2008
In animals, the adipocyte-derived hormone leptin induces increased blood pressure centrally via the hypothalamus, and one study has reported that exercise training decreases hypothalamic leptin receptor expression. In humans, high circulating leptin concentrations are associated with high blood pressure, but the possible influence of physical activity or aerobic capacity on ...
Uchiyama Akira - - 2008
There are few longitudinal studies on the associations of obesity with hypertension in young adults. To analyze longitudinally to what extent weight gain associates with hypertension in young adults. The subjects of this study consisted of 6,178 university students (male 4,098; female 2,080). The associations of hypertension with body type ...
Agapitov Alexei Vasilievich AV Institute for Clinical and Translational Science, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, - - 2008
Obesity increases the risk of hypertension and its cardiovascular complications. This has been partly attributed to increased sympathetic nerve activity, as assessed by microneurography and catecholamine assays. However, increased vasoconstriction in response to obesity-induced sympathoactivation has not been unequivocally demonstrated in obese subjects without hypertension. We evaluated sympathetic alpha-adrenergic vascular ...
Hawkesworth Sophie S MRC International Nutrition Group, London School of Hygiene and Tropical Medicine, London, UK. - - 2009
Birthweight, and by inference maternal nutrition during pregnancy, is thought to be an important determinant of offspring blood pressure but the evidence base for this in humans is lacking data from randomized controlled trials. The offspring from a maternal prenatal protein-energy supplementation trial were enrolled into a follow-up study of ...
de Vries Willem B - - 2008
OBJECTIVE: To study whether antenatal or neonatal glucocorticoid therapy to reduce the incidence and severity of chronic lung disease in preterm infants is associated with long-term adverse cardiac effects and hypertension. DESIGN: Retrospective matched-cohort study. SETTING: Outpatient clinic of a tertiary care hospital. PARTICIPANTS: One hundred ninety-three children aged 7 ...
Genovesi Simonetta - - 2008
OBJECTIVE: To investigate the ability of BMI and waist circumference, single and combined, in identifying children who are at risk of hypertension and in influencing absolute blood pressure values. METHODS: The body weight, height, waist circumference and blood pressure of 4177 5-11-year-old school children [2005 (48%) girls] were collected. Elevated ...
Santoro Nicola - - 2008
OBJECTIVE: To verify whether peptide YY (PYY) and its Y2 receptor (Y2R) gene variants can be associated with obesity or hypertension or both in a cohort of obese children and adolescents. PATIENTS AND METHODS: Two hundred and twenty-nine obese children (105 girls, mean z-score BMI 5.1 +/- 2.4; mean age ...
Van Putte-Katier Nienke - - 2008
We investigated whether obese children and adolescents have early echocardiographic signs of subclinical cardiac dysfunction and evaluated the respective influence of obesity per se versus parameters of carbohydrate and lipid metabolism that are frequently abnormal in obese subjects. The role of tissue Doppler imaging as a screening tool for these ...
Rotteveel Joost - - 2008
OBJECTIVE: Preterm infants are at increased risk to develop insulin resistance and high blood pressure. The influence of growth during childhood is not well established. METHODS: We investigated childhood growth patterns in relation to blood pressure and insulin sensitivity, measured by the hyperinsulinemic euglycemic clamp, in young adults. We compared ...
Mercado Arlene B - - 2008
Continuous or ambulatory blood pressure monitoring (CBPM or ABPM) is becoming a useful tool in the early detection of hypertension in children and adolescents. With increased obesity in pediatrics, chronic diseases such as hypertension, diabetes, dyslipidemia and metabolic syndrome which was more commonly seen in adults in the early years, ...
Fass Ronnie - - 2008
Obesity has increased dramatically in the last 30 years, affecting 33% of the adult population in the United States. Increase in body mass index has been shown to be associated with the increase in the prevalence of gastroesophageal reflux disease (GERD) symptoms, esophageal mucosal injury, and GERD complications. The putative ...
Jones Alexander A MRC Epidemiology Resource Centre, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK. - - 2008
Increasing evidence suggests that adverse prenatal environments, as indicated by low birth weight, cause long-term changes in cardiovascular physiology that predispose to circulatory disease. The mechanisms are poorly understood, most human studies have been carried out in adults and little is known about early pathophysiological changes. Therefore, we have assessed ...
Singer Gregory M - - 2008
The epidemic of obesity in the United States and around the world is intensifying in severity and scope and has been implicated as an underlying mechanism in systemic hypertension. Obese hypertensive individuals characteristically exhibit volume congestion, relative elevation in heart rate, and high cardiac output with concomitant activation of the ...
Carroll Douglas D School of Sport and Exercise Sciences, University of Birmingham, Birmingham, England, UK. - - 2008
To examine the association between adiposity and the magnitude of cardiovascular reactions to acute psychological stress cross-sectionally and prospectively in a large community sample. Blood pressure and heart rate (HR) were measured at rest and in response to a brief time-pressured mental arithmetic stress in 1647 adults. At the same ...
Cheung Bmy - - 2008
Obesity is known to be a major aetiological factor in the development of hypertension. It also leads to dyslipidaemia and raised blood glucose. All of these are components of the metabolic syndrome. Thus, hypertension, as part of the syndrome, is often found together with these other abnormalities. Obesity raises blood ...
Chaix Basile - - 2008
OBJECTIVES: Few studies have examined whether social characteristics of the residential environment are associated with blood pressure after controlling for individual sociodemographic characteristics. Even less is known about the processes by which these associations operate. Therefore, we examined whether distinct dimensions of the residential environment (socioeconomic position and urbanicity) were ...
Apostolidou Maria T - - 2008
AIM: Pediatric studies revealed associations of obstructive sleep-disordered breathing (SDB) with inflammation, metabolic dysfunction, and elevated blood pressure. Evidence about effects of adenotonsillectomy on these abnormalities is scarce. Aim of this investigation was to assess changes in C-reactive protein (CRP), circulating intercellular adhesion molecule-1 (cICAM-1), insulin and blood pressure levels ...
Beydoun May A MA Department of Environmental Health Sciences, Center for Human Nutrition, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, - - 2008
Recent studies suggest dairy consumption and associated nutrients may be protective against some of the components of the metabolic syndrome (MetS). We examined the association between consumption of a variety of dairy products and their related nutrients with obesity, central obesity, and MetS, and attempted to explain some of the ...
Pandolfino John E - - 2008
The rates of obesity have doubled over the last 22 yr in the United States. Similarly, the prevalence of gastroesophageal reflux disease (GERD) has also been rising in the United States, with studies suggesting it may now be as high as 1 in 5. Given these parallel time trends, it ...
Karmazyn Morris - - 2008
Adipokines represent a family of proteins released by adipocytes that affect various biological processes including metabolism, satiety, inflammation, and cardiovascular function. The first adipokine to be identified is leptin, a product of the obesity gene whose primary function is to act as a satiety factor. However, it is now recognized ...
Srivastava Neena - - 2008
Background The pathophysiology of obesity is known to be influenced by alterations in lipid levels. We aimed to evaluate association of cholesteryl ester transfer protein (CETP) and apolipoprotein (APO) E gene variants with asymptomatic obesity. Methods A total of 437 subjects, 159 asymptomatic obese (BMI = 29.29 +/- 3.76) and ...
Dwyer T T Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia. - - 2008
To examine whether the inverse association between birth weight and blood pressure varies by skin pigmentation and/or related genotypes. 671 children from a predominantly caucasian birth cohort were followed-up to adolescence (mean (SD) age 14.4 (0.64)). Data on birth weight, socioeconomic status, maternal antenatal smoking, adolescent blood pressure and polymorphisms ...
Sarzani R - - 2008
The effects of exogenous and endogenous cannabinoids on the cardiovascular system have been the focus of extensive research. The direct and indirect effects of cannabinoids on heart and blood vessels depend upon experimental conditions, animal species, and, in humans, clinical background. Cannabinoids decrease blood pressure in hypertensive rodents primarily because ...
Yamane Teiichi - - 2008
RATIONALE: Although arterial oxygen concentration decreases in obese subjects, the mechanism for this remains to be determined. OBJECTIVES: The blood gas level in each pulmonary vein (PV) was measured in supine subjects with diverse body mass index (BMI) values, to determine whether there was a regional insufficiency in gas exchange ...
Grassi G - - 2008
Obesity-related hypertension represents a common clinical condition characterised by complex pathophysiological and therapeutic features. From a pathophysiological view point, results of experimental and animal studies have led to the hypothesis that neurogenic mechanisms participate in the development and progression of the disease. The hypothesis is based on the evidence that ...
Mizia-Stec Katarzyna - - 2008
BACKGROUND: In animal models ghrelin reduces cardiac afterload and increases cardiac output via receptors in the cardiovascular system. The aim of our study was to evaluate a potential relationship between weight loss treatment, blood pressure and serum ghrelin concentrations in obese women. MATERIAL AND METHODS: A group of 37 obese ...
Gundogdu Zuhal - - 2008
AIM: To investigate the relationship between BMI and blood pressure as this is of crucial interest in evaluating both public health and the clinical impact of the so-called obesity epidemic. METHODS: Data were gathered from 1899 children aged between 6 and 14 years, analysing and evaluating a possible relationship between ...
Frohlich Edward D - - 2008
Obesity and hypertension frequently coexist and are considered major "factors of risk" associated with coronary heart disease. This report identifies the systemic and renal hemodynamic alterations associated with obesity in normotensive and essential hypertensive patients. An expanded intravascular (plasma) volume is associated with obesity, which is related to an increased ...
Wofford Marion R - - 2008
Hypertension causes a significant disease burden in all racial and ethnic groups and is directly attributable to excess weight in most cases. The relationship between increasing body mass index and hypertension prevalence has been recognized for decades. Epidemiologic studies clearly demonstrate the correlation between body weight and blood pressure in ...
Schwartz Ann M - - 2008
The purpose of this study was to investigate the combined impact of obesity and physical activity (PA) on the health of older adults. Pedometer-determined steps/d, body-mass index (BMI), resting blood pressure, and fasting glucose (FG) were assessed in 137 older adults (69.0 +/- 8.9 yr). The active group (>4,227 steps/d) ...
Takase Hiroyuki - - 2008
Each component of the metabolic syndrome is not necessarily clustered coincidentally. Thus, subjects who have obesity, dyslipidemia or impaired glucose tolerance may be at high risk for the development of hypertension. We studied the predictive value of the following for the development of hypertension: obesity (body mass index > or ...
Morris Margaret J - - 2008
1. Obesity is an important risk factor for hypertension and its incidence is increasing around the world. 2. The mechanisms underlying obesity-related hypertension include sympathetic activation, altered vascular responses, hormonal changes, enhanced inflammatory markers and structural changes. 3. This review summarizes recent evidence of the underlying impact of obesity on ...
Sung Shih-Hsien - - 2008
The role of adiponectin, a marker of the metabolic syndrome, on the pathogenesis of hypertension in comparison with markers of adipose tissue mass (leptin) and inflammation (high-sensitivity C-reactive protein [hs-CRP]) remains to be clarified. The eligible study population consisted of 2,045 residents aged > or =40 years who had participated ...
McCarthy William J - - 2008
INTRODUCTION: To identify anthropometric and fitness correlates of elevated blood pressure, serum cholesterol, and glycated hemoglobin, we examined anthropometric and physiologic biomarkers among racial/ethnic minority children aged 11 to 13 years in two urban Los Angeles middle schools. We explored the potential for using obesity or fitness level as screening ...
Mimoun Emmanuelle - - 2008
OBJECTIVE: We investigated whether metabolic syndrome, defined in 3 different ways (2 commonly used and 1 novel) is associated with arterial alterations in obese children. STUDY DESIGN: The study group comprised 384 obese children age 2.5 to 18 years. Blood pressure, fasting blood glucose, blood insulin, plasma lipids, and body ...
L?pez-Jaramillo Patricio - - 2008
BACKGROUND: The link between inflammation, obesity, and cardiovascular disease (CVD) has been described in adult populations but few data are available with respect to children. The aim of this study was to describe the inter-relationships between adiposity, C-reactive protein (CRP) plasma concentrations, and blood pressure levels in a Hispanic pediatric ...
Zavorsky G S - - 2008
The literature on pulmonary gas exchange at rest, during exercise, and with weight loss in the morbidly obese (body mass index or BMI > or = 40 kg m(-2)) is reviewed. Forty-one studies were found (768 subjects weighted mean = 40 years old, BMI = 48 kg m(-2)). The alveolar-to-arterial ...
van Rij A M - - 2008
OBJECTIVES: The clinical severity of venous disease is often worse in obese patients. The objectives of this study were to compare lower limb venous physiology assessed by air plethysmography in a large group of obese and normal-weight patients; to consider the effect of posture on these measures and on foot ...
Libby Gillian - - 2008
PURPOSE: We sought to assess the association between birth weight and adult systolic blood pressure in a relatively young, healthy, working population with prospectively collected birth data and blood pressure consistently recorded. METHODS: Detailed information on pregnancy and birth came from the Walker cohort, a database of babies born in ...
Gerten Kimberly A - - 2008
OBJECTIVE: The purpose of this study was to describe the effect of the lifting maneuver and the quantity of weight lifted on the generation of intraabdominal pressure. STUDY DESIGN: Forty-one women who underwent urodynamic evaluation performed 4 lifting maneuvers, each while lifting 0, 2.5, 5, 10, and 15 kg. The ...
Truesdale Kimberly P KP Department of Nutrition, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. - - 2008
The objective of this study was to examine the effect of weight history on blood pressure. Extant data from the Atherosclerosis Risk in Communities (ARIC) study were used to compare blood pressure in women (n=5,675) and men (n=4,893) with different 3-year weight histories, but similar current BMI. We used mixed ...
Li Hung-Yuan HY Department of Internal Medicine, National Taiwan University Hospital, Taipei, - - 2008
The association between plasma adiponectin level and blood pressure remains inconclusive. Because obese subjects may have different mechanisms to regulate blood pressure, we hypothesized that obesity may be an important modifier. In order to minimize confounding effects from unidentified factors, a family-based design was employed to explore the relationship. A ...
Ofuya, Z M; ;
The cardiovascular and respiratory parameters of obese and non-obese residents in Port Harcourt were studied using the University of Port Harcourt as a case study. The aim was to investigate the effect of obesity on the above -mentioned parameters. A total forty subjects (twenty males and twenty females) were used ...
Staudt J M - - 2008
Compartment pressures have not previously been studied in healthy children. We compared the pressures in the four lower leg compartments of healthy children with those of healthy adults. We included patients aged between two months and six years, and measured the pressures in 80 compartments of 20 healthy children using ...
Sen Yasar - - 2008
OBJECTIVES: The aim of this study was to investigate the relationship between the varying degrees of obesity and blood glucocorticoid levels in obese children and adolescents with and without metabolic syndrome features. METHODS: We studied 241 obese children and adolescents aged between 2 and 17.6 years; 127 boys and 114 ...
Aggoun Yacine - - 2008
AIMS: To determine whether impaired brachial endothelial (flow-mediated dilation, FMD) and smooth muscle function (nitroglycerin-mediated dilation, NTGMD), and remodelling of the common carotid artery (CCA) develop before puberty in obese children. METHODS AND RESULTS: Arterial intima-media thickness (IMT), FMD and NTGMD were measured by high-resolution ultrasound in 48 obese and ...
Rosa Eduardo Cantoni - - 2008
OBJECTIVE: Blood pressure (BP) and target organ responses to antihypertensive drugs are not well established in hypertensive obese patients. This study is aimed at evaluating the effects of obesity and adiposity distribution patterns on these responses. METHODS: 49 hypertensive obese women were designated to different groups according to waist to ...
< 1 2 3 4 5 6 7 8 9 10 >