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Litwin Mieczyslaw - - 2010
We assessed the effects of 12 months of non-pharmacological and pharmacological therapy on 24-h ambulatory blood pressure, regression of target organ damage (TOD) and metabolic abnormalities in 86 children (14.1 ± 2.4 years) with primary hypertension. Twenty-four hour systolic and diastolic blood pressure (BP) decreased (130 ± 8 vs 126 ± 8, 73 ± 7 vs 70 ± 7, p = 0.0001 ...
Goel Ruchika - - 2010
Primary hypertension has become increasingly common in children but remains largely understudied, underdiagnosed and undertreated. This study examines the relationship between hypertension in adolescents and various markers of obesity, serum lipid levels, fasting blood glucose (FBG), haemoglobin A1c (HbA1c) and family history of hypertension. DESIGN/SETTINGS: A cross-sectional population-based study of ...
Kotchen Theodore A - - 2010
The prevalence of obesity, including childhood obesity, is increasing worldwide. Weight gain is associated with increases in arterial pressure, and it has been estimated that 60-70% of hypertension in adults is attributable to adiposity. Centrally located body fat, associated with insulin resistance and dyslipidemia, is a more potent determinant of ...
Roelofs Rik - - 2010
BACKGROUND: Asthma has been linked to cardiovascular diseases (CVDs) and related risk factors such as hypertension in adults. It is unclear whether the relationship between asthma and hypertension found among adults is also observed in adolescents. Hence, the authors examined asthma and its association with prehypertension and hypertension among adolescents ...
Naumnik Beata - - 2010
The worldwide prevalence of obesity and its associated metabolic and cardiovascular disorders has risen dramatically within the past 2 decades. Our objective is to review the mechanisms that link obesity with altered kidney function. Current evidence suggests that excess weight gain may be responsible for 65-75% of the risk for ...
Jansen Pieter M - - 2010
Obesity is a major risk factor for the development of hypertension. Because the prevalence of obesity is increasing worldwide, the prevalence of obesity hypertension is also increasing. Importantly, hypertension in obesity is commonly complicated by dyslipidemia and type 2 diabetes mellitus and hence imposes a high cardiovascular disease risk. Furthermore, ...
Badeli Hamidreza - - 2010
Childhood hypertension has been extensively focused on in the past decades because of its increasing incidence, which is related to physicians' awareness and the increasing number of obese children. Age, gender, and body size are the main determinants of blood pressure in children. The revised childhood blood pressure tables of ...
Shaikh Wasim A - - 2010
The current study was conducted to determine the effect of adiposity on vascular distensibility in Gujarati Indian adolescents as research indicating the pathogenesis of hypertension among overweight and/or obese Indian adolescents is scant and ethnic differences exist in the pathogenesis of hypertension A cross-sectional study was conducted on 488 Gujarati ...
Markus Marcello Ricardo Paulista - - 2010
We studied the relationship between changes in body composition and changes in blood pressure levels. The mechanisms underlying the frequently observed progression from pre-hypertension to hypertension are poorly understood. We examined 1,145 subjects from a population-based survey at baseline in 1994/1995 and at follow-up in 2004/2005. First, we studied individuals ...
Denburg Michelle R - - 2010
Obesity and hypertension frequently complicate renal transplantation (RTxp). The objective was to assess relations among obesity, hypertension, and glucocorticoids in pediatric RTxp recipients. A retrospective cohort study was carried out in 141 RTxp recipients, 2-21 years of age, with >or=12 months of follow-up. Body mass index Z-score (BMI-Z), systolic and ...
Dhuper Sarita - - 2011
Obesity, especially when complicated with hypertension, is associated with structural and functional cardiac changes. Recent studies have focused on the prognostic impact of the type of left ventricular (LV) geometric remodeling. This study looked at the prevalence and clinical correlates of LV geometric patterns and their relation to cardiac function ...
Monostori Péter - - 2010
The microvascular responses to endothelium-dependent vasodilators (e.g., acetylcholine), endothelium-independent vasodilators (e.g., sodium nitroprusside), and to local heating were studied (for the first time) in adolescents with essential hypertension, grouped according to their body mass index. The forearm microvascular reactivities of thirty-three hypertensive adolescents (ten lean, 13 overweight, and ten obese) ...
Arslan Erol - - 2010
INTRODUCTION: QT prolongation and obesity are associated with ventricular arrhythmia and sudden cardiac death. The relationship between uncomplicated obesity and QT interval prolongation is not clear. OBJECTIVES: The aim of the study was to investigate the effects of uncomplicated obesity on QT interval in young men. PATIENTS AND METHODS: A ...
Pelosi Paolo - - 2010
Obesity is a metabolic disease that is on the increase all over the world. Up to 35% of the population in North America and 15-20% in Europe can be considered obese. Since these patients are characterised by several systemic physiopathological alterations, the perioperative management may present some problems, mainly related ...
Raj Manu - - 2010
OBJECTIVE: To determine blood pressure distribution in schoolchildren and to derive population specific reference values appropriate for age, gender and height status. DESIGN: Cross sectional observational study. SETTING: Schools in Ernakulam district, Kerala, India, during 2005-06. METHODS: Stratified random cluster sampling method was used to select the children. Blood pressure ...
Johnson J A - - 2010
Low pressure treatment in flexible polyvinyl chloride containers is a potential alternative to chemical fumigants for California tree nuts. Laboratory studies investigated the effect of relative humidity and product moisture on weight loss and mortality of diapausing and nondiapausing larvae of the Indianmeal moth, Plodia interpunctella (Hübner) (Lepidoptera: Pyralidae), exposed ...
Akgun Cihangir - - 2010
Although hypertension is a well-documented risk factor for cardiovascular diseases, including myocardial infarction and stroke, in adults, only recently has knowledge about childhood hypertension increased significantly. To determine the incidence of asymptomatic hypertension in school-age children. Children in primary school were chosen with a randomized sampling method. During measurement of ...
Celoria Bruno M J - - 2010
Considering that prehypertension is associated with an increase in cardiovascular risk, hypoadiponectinemia seems to be a predictor of hypertension. This study investigated whether adiponectin plasma levels are affected in Brazilian obese prehypertensives compared with those in normotensives and hypertensives. The study involved 96 multiethnic obese subjects (mean age = 42.8-11.9 ...
Shankaran Seetha - - 2010
Prenatal cocaine exposure has been linked to intrauterine growth retardation and poor birth outcomes; little is known about the effects on longer-term medical outcomes, such as overweight status and hypertension in childhood. Our objective was to examine the association between prenatal cocaine exposure and BMI and blood pressure at 9 ...
Rocha-Goldberg Maria Del Pilar Mdel - - 2010
To assess the feasibility of a culturally tailored behavioral intervention for improving hypertension-related health behaviors in Hispanic/Latino adults. Feasibility pilot study in a community health center and a Latino organization in Durham, North Carolina. The culturally adapted behavioral intervention consisted of six weekly group sessions incorporating motivational interviewing techniques. Goals ...
McCambridge Teri M - - 2010
Children and adolescents who have hypertension may be at risk for complications when exercise causes their blood pressure to rise even higher. The purpose of this statement is to update recommendations concerning the athletic participation of individuals with hypertension, including special populations such as those with spinal cord injuries or ...
Agarwal Rajiv - - 2010
Achieving and maintaining dry-weight appears to be an effective but forgotten strategy in controlling and maintaining normotension among hypertensive patients on hemodialysis. Qualitative review of literature to define dry-weight and its utility in achieving blood pressure control. The concept of dry-weight has evolved over time and its definition has changed. ...
Obarzanek Eva - - 2010
To estimate the prevalence and incidence of hypertension and prehypertension and associated factors in adolescent girls. A total of 2368 girls (49% Caucasian, 51% African-American) aged 9 or 10 years enrolled in the National Heart, Lung, and Blood Institute Growth and Health Study had blood pressure, height, and weight measured ...
Mørkedal Bjørn - - 2011
Background Blood pressure is positively associated with ischaemic heart disease (IHD) mortality, but the strength of the association declines with age, and may differ between lean and obese people. Objective To study the association of blood pressure with IHD mortality stratified by attained age (<65 and ≥65&emsp14;years) and by body ...
Caserta Carmelo Antonio - - 2010
The objective of this study was to determine, in an adolescent population, the prevalence of nonalcoholic fatty liver disease (NAFLD) and the association of NAFLD and cardiovascular risk factors with carotid artery intima-media thickness (IMT), a marker of subclinical atherosclerosis. The authors conducted a population-based study among 642 randomly selected ...
Flynn Joseph T - - 2010
The field of childhood hypertension has been changing rapidly since publication of the most recent consensus guidelines contained in the 2004 'Fourth Report'. Several epidemiologic studies have indicated that the prevalence of hypertension in children and adolescents is on the increase. A major factor behind this increase is the childhood ...
Ansa V O - - 2010
Emerging data suggest that essential or primary hypertension occurs in the young. Parental socioeconomic status may play a role but the exact mechanisms still remain unclear. This study was aimed at determining the relationship between parental socioeconomic status and casual blood pressure in adolescents. One thousand and eight adolescents attending ...
Kotsis Vasilios - - 2010
The relationship between obesity and hypertension is well established both in children and adults. The mechanisms through which obesity directly causes hypertension are still an area of research. Activation of the sympathetic nervous system has been considered to have an important function in the pathogenesis of obesity-related hypertension. The arterial-pressure ...
Di Guardo Antonino - - 2010
The links between obstructive sleep apnoea and hypertension are well established; obstructive sleep apnoea is reported in up to 30% of patients with hypertension, although it is frequently underdiagnosed. Physicians can assess the degree of sleepiness by administering the Epworth Sleepiness Scale, but the large number of patients with hypertension ...
Chockalingam Arun - - 2010
World Hypertension Day is an initiative of the World Hypertension League. This year's theme is "Healthy weight - healthy blood pressure". According to the World Health Organization, more than one billion people worldwide are reported to be overweight and more than 300 million people are obese. Obesity is linked to ...
Mühle Anja - - 2010
Low birth weight is associated with an increased risk of metabolic dysfunction and arterial hypertension in later life. Because of their reduced birth weight twins have been used repeatedly as a natural model to investigate prenatal programming of hypertension. To reveal an early impact of lower nephron endowment on blood ...
Fox Mark D - - 2010
OBJECTIVE: The purpose of this study is to examine the association of obesity and elevated blood pressure among adolescent patients in a pediatric resident continuity clinic. METHODS: Blood pressure and anthropometric data from adolescent patients (ages 12-18 years) in a resident continuity clinic were analyzed. Age-and gender-specific BMI percentiles, and ...
Nwachukwu D C - - 2010
BACKGROUND: Body Mass Index (BMI) has been described as a significant predictor of Blood Pressure (B.P) but few studies have demonstrated this association in our environment. The study aims to determine the pattern of relationship between BMI and blood pressure in our environment. METHODOLOGY: Two thousand and ninety six (2096) ...
Hall John E - - 2010
Excess weight gain contributes to increased blood pressure in most patients with essential hypertension. Although the mechanisms of obesity hypertension are not fully understood, increased renal sodium reabsorption and impaired pressure natriuresis play key roles. Several mechanisms contribute to altered kidney function and hypertension in obesity, including activation of the ...
Viazzi F - - 2011
The development of sub-clinical organ damage precedes and predicts the occurrence of cardiovascular (CV) events in hypertensive as well as in obese patients. We investigated the prevalence and clinical correlates of organ damage (OD), namely carotid atherosclerosis (US scan) and urine albumin to creatinine ratio (three non-consecutive first morning samples) ...
Smith Patrick J - - 2010
High blood pressure increases the risks of stroke, dementia, and neurocognitive dysfunction. Although aerobic exercise and dietary modifications have been shown to reduce blood pressure, no randomized trials have examined the effects of aerobic exercise combined with dietary modification on neurocognitive functioning in individuals with high blood pressure (ie, prehypertension ...
Genovesi Simonetta - - 2010
To assess the prevalence of hypertension (H), prehypertension (PH), and transient elevated blood pressure (TH) and their relationship with weight class and waist circumference (WC) in an unselected population of Northern Italian children. A cross-sectional study was conducted in 5,131 children (5-11 years). Weight class was defined according to the ...
Aguilar Alexandra - - 2010
OBJECTIVES: To evaluate the relationship among ambulatory blood pressure (ABP), body mass index (BMI), and homeostasis model assessment (HOMA) in a multi-ethnic population of obese children with clinic blood pressure in the reference range. STUDY DESIGN: A total of 43 obese normotensive children (7-17 years old) were recruited. ABP monitoring, ...
Jain Anil Kumar - - 2010
BACKGROUND: Perioperative fluid administration in morbidly obese patients is critical. There is scarcity of scientific information in literature on amount and rate of its application. Functional parameters (stroke volume variation (SVV), pulse pressure variation) are considered more accurate predictor of volume status of patients than blood pressure and central venous ...
Maayan Lawrence A - - 2010
OBJECTIVE: To document prospective weight and anthropometric changes in children and adolescents during the first 12 weeks of treatment with risperidone and evaluate metabolic outcomes including plasma leptin levels. METHOD: Eight patients with psychotic disorders (ages 11-17) who had started risperidone (mean: 1.80 mg/day; sd = 1.04) in the prior ...
Syed Mohsin - - 2010
Hypertension, diabetes, and obesity frequently coexist and significantly contribute to cardiovascular morbidity and mortality. Weight loss in obese individuals has been associated with improved blood pressure control and regression in left ventricular (LV) hypertrophy. The authors investigated the impact of comorbidity and medication on clinical and echocardiographic parameters after weight ...
Vuksan Vladimir - - 2010
The prevalence of the metabolic syndrome (MetS) is increasing worldwide and prevention represents a major challenge. Usually identified in middle age, the MetS has pediatric roots and there are variable incidence rates between ethnic groups. Due to the difficulty of diagnosis, it remains largely undetected in adolescents. To assess the ...
Yiannikouris Frederique - - 2010
In contrast to previous understanding, adipocytes are now known to produce an array of factors collectively termed 'adipokines', several of which have effects on the cardiovascular system. The marked rise in prevalence of obesity warrants investigation into the role of adipocyte-derived factors in the regulation of blood pressure. For example, ...
Monteiro M - - 2010
BACKGROUND: Menopause is associated with a decrease in fat-free mass and an increase in fat mass. Sarcopenic obesity is more strongly associated with physical limitations than either obesity or sarcopenia and their effect in plantar pressure is not known. Consequently, the scope of the present study was to examine the ...
Raj M - - 2010
The aim of the study was to examine the association of a trend in body mass index (BMI) status with current blood pressure in a cohort of school children from South India. A population of 25,228 children was selected using stratified random sampling method. Height and weight were measured in ...
Schmid Klaus - - 2010
Abnormalities of the autonomic nervous system have been repeatedly shown in hypertension. We studied the associations between being overweight, blood pressure, cardiac vagal tone as measured by variability in heart rate, and well-being in a large cohort of young men. We hypothesised an inverse correlation between body mass index and ...
Papandreou D - - 2010
Hyperhomocysteinemia is emerging as an independent predictor of cardiovascular disease and hypertension among children. The aim of the study was to examine the effects of oral folic acid on homocysteine and blood pressure. Folic acid supplementation has been found to reduce homocysteine levels and in some cases blood pressure. Five ...
Hollar Danielle - - 2010
Childhood obesity and related health consequences continue to be major clinical and public health issues in the United States. Schools provide an opportunity to implement obesity prevention strategies to large and diverse pediatric audiences. Healthier Options for Public Schoolchildren was a quasiexperimental elementary school-based obesity prevention intervention targeting ethnically diverse ...
Ta?oy G?lten - - 2010
BACKGROUND: To investigate the effect of body mass index (BMI) on heart rate variability (HRV) and inflammatory parameters in patients with heart failure. METHODS: We analyzed 55 consecutive patients (mean age, 63.5 +/- 12.8 years; male/female, 39/16) with symptomatic left ventricular systolic (ejection fraction <45%) heart failure. The participants were ...
Lands L C - - 2010
Cystic fibrosis (CF) is characterized by malnutrition, chronic pulmonary inflammation, and oxidative stress. Whey protein is rich in sulfhydryl groups and is recognized for its ability to increase glutathione and reduce oxidative stress. Previously, we have shown that supplementation with whey increased intracellular glutathione levels in patients with CF. We ...
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