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Porcello Marrone Luiz Carlos LC Neurology Service, Hospital São Lucas and Instituto do Cérebro do Rio Grande do Sul, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS). Electronic address: - - 2014
Posterior reversible encephalopathy syndrome (PRES) is a clinical entity characterized by headaches, altered mental status, seizures, and visual disturbances and is associated with white matter vasogenic edema. There are no experimental models to study PRES brain changes. Twenty-eight pregnant Wistar rats were divided into 4 groups of 7: (1) pregnant-control; ...
Thisted Dorthe Louise Ahrenkiel DL University of Copenhagen, Hvidovre Hospital, Dept. of Gynaecology & Obstetrics, Hvidovre, - - 2014
Abstract Objective To evaluate the effect of immersion into water on maternal blood pressure, amount of amniotic fluid and on the fetoplacental- and uteroplacental circulation in healthy women with an uncomplicated singleton pregnancy. Methods Twenty-five healthy women were included. Recordings of blood pressure, deepest vertical pocket of amniotic fluid and ...
Bø Kari K Department of Sports Medicine, Norwegian School of Sport Sciences, PO Box 4014, Ullevål stadion, 0806, Oslo, Norway, - - 2014
The aims of the present study were to investigate the correlation among vaginal resting pressure and pelvic floor muscle (PFM) strength and endurance, and the correlation between the same variables and levator hiatus (LH) dimensions in nulliparous pregnant women. This was a cross-sectional study of 300 nulliparous pregnant women, mean ...
Kim Haroo H Department of Physical Therapy, College of Rehabilitation Science, Daegu University, Republic of - - 2014
[Purpose] The purpose of this study was to compare the effect of childbirth delivery method on vaginal pressure and abdominal thickness during the Valsalva maneuver (VAL). [Subjects] Thirty healthy female volunteers (26-39 years of age) were selected for this research. Their delivery histories were: nulliparous 10, vaginal delivery 10, and Cesarean ...
Chuong Cheng-Jen CJ Joint Graduate Program in Biomedical Engineering, University of Texas, Arlington, United States; Joint Graduate Program in Biomedical Engineering, University of Texas Southwestern Medical Center, Dallas, United States; Bioengineering Department, University of Texas, Arlington, TX 76019, United States. Electronic address: - - 2013
In-vivo measurement of the viscoelastic properties of the prolapsed anterior vaginal wall (AVW) in post-menopausal women undergoing cystocele repair. A BTC-2000™ cutometer-like instrument was introduced during vaginal repair of symptomatic stage 2-3 AVW prolapse. Under anesthesia, 10-mm orifice probe was applied to the AVW at the level of the bladder ...
Kruger Jennifer - - 2013
INTRODUCTION AND HYPOTHESIS: The influence of intra-abdominal pressure (IAP) on prolapse development is poorly understood. Nonetheless, chronic cough, high BMI, or heavy lifting predisposes women to pelvic organ prolapse (POP). This study aims to develop and test a novel, wireless intra-vaginal pressure sensor (IVPS) to quantify intra-abdominal pressure changes across ...
Kuenzel Julian - - 2013
OBJECTIVE: The herbal agent celandine is thought to have mainly spasmolytic effects, but in the uterus it is regarded as promoting contractions, which can offer promising and innovative options for optimizing artificial reproduction. The aim of the present study was to investigate the effect of celandine on the uterine muscle, ...
Cagnacci Angelo - - 2013
BACKGROUND: Hypertension is recognized as a major risk factor for coronary, cerebral and renal vascular disease. Hormonal methods of contraception may increase the risk for cardiovascular events. We evaluated whether the combined hormonal contraceptive vaginal ring that releases 15-mcg ethinylestradiol and 120 mcg of etonogestrel each day influences 24-h ambulatory ...
Rodgers Blake Conley - - 2013
A 34-year-old gravida 2, para 1 woman delivered a viable male infant and developed retained placenta due to entrapment. A nitroglycerin tablet was used to relax the lower uterine segment and cervix, which allowed the placenta to pass through the cervix for delivery. The nitroglycerin tablet was placed in the ...
Withers S - - 2012
An adequate blood supply is essential for the maintenance of uterine function and fetal health during parturition. However, labouring uterine contractions will impart compressive forces on small uterine arteries (SUA). We demonstrate that isolated, pressurised rat SUA arteries, pre-constricted with arginine vasopressin or high potassium solution, exhibit regulatory responses to ...
Campbell D J - - 2012
BACKGROUND: A significant proportion of individuals taking antihypertensive therapies fail to achieve blood pressures < 140/90 mmHg. In order to develop strategies for improved treatment of blood pressure we examined the association of blood pressure control with antihypertensive therapies, and clinical and lifestyle factors in a cohort of adults at ...
Karnath Bernard M - - 2012
A poor response to therapy should trigger a search for a secondary cause of hypertension. Use this review as your guide.
Briasoulis Alexandros - - 2012
Despite the presence of seven different antihypertensive drug classes and over 120 different antihypertensive medications, about 48 % of the 75 million people with hypertension are not reaching their target blood pressure goals. One of the reasons for this lack of control is the failure to adequately inhibit the sympathetic nervous ...
Zilinski Jodi L - - 2012
ABSTRACT: INTRODUCTION: To investigate prognostic utility of biomarkers in advanced stage heart failure (HF) patients requiring intensive care unit (ICU) admission for pulmonary artery catheter (PAC) guided therapy. METHODS: 30 patients admitted to an ICU for PAC guided HF therapy were enrolled; concentrations of soluble ST2 (sST2), highly sensitive troponin ...
Thomas George - - 2012
Renal sympathetic denervation has shown promise in treating hypertension resistant to drug therapy. This procedure lowers blood pressure via targeted attenuation of renal sympathetic tone, and it has a favorable safety profile. But although there is reason for cautious optimism, we should keep in mind that the mechanisms of hypertension ...
Belcik J Todd JT Division of Cardiovascular Medicine, Oregon Health & Science University, Portland, Oregon 97239, - - 2012
This study sought to evaluate the contribution of microvascular functional rarefaction and changes in vascular mechanical properties to the development of hypertension and secondary ventricular remodeling that occurs with anti-vascular endothelial growth factor (VEGF) therapy. Hypertension is a common side effect of VEGF inhibitors used in cancer medicine. Mice were ...
Desai Kunj K - - 2012
Negative pressure wound therapy (NPWT) has overwhelmed the wound-healing world. A systematic review puts it into perspective. The authors have developed an algorithm after careful evaluation and analysis of the scientific literature supporting the use of these devices. This article describes mechanisms of action, technical considerations, wound preparation, and clinical ...
Bortolotti Albert - - 2012
ABSTRACT: Electroconvulsive therapy cannot proceed safely unless blood pressure is within the reference range. Finding the cause of very high or low blood pressure can be very difficult, time consuming, and expensive. We suggest a more valid and reliable time to check blood pressure. This is highlighted in the case ...
Zhu Dingliang - - 2012
BACKGROUND: A majority of hypertensives require treatment with ≥2 antihypertensive therapies to achieve blood pressure (BP) goals. Single-pill combinations (SPC) may improve convenience and adherence to therapy and reduce health care resource use and costs. The antihypertensive effects of amlodipine and valsartan are well established. This study evaluated the efficacy ...
Kashiwagi Kenji - - 2012
PURPOSE: To prospectively assess the efficacy of switching to a travoprost/timolol fixed-combination (TTFC) therapy from latanoprost monotherapy. METHODS: This was a prospective, open-label study in which patients with either primary open-angle glaucoma or ocular hypertension who had been undergoing latanoprost monotherapy for at least 3 months were enrolled. Baseline was defined ...
Egan Brent M - - 2012
Initial antihypertensive therapy with single-pill combinations produced more rapid blood pressure control than initial monotherapy in clinical trials. Other studies reported better cardiovascular outcomes in patients achieving lower blood pressure during the first treatment year. We assessed the effectiveness of initial antihypertensive monotherapy, free combinations, and single-pill combinations in controlling ...
Ferguson-Myrthil Nadia - - 2012
Vasopressors are a heterogeneous potent class of medications designed to increase blood pressure in emergent hypotensive situations. The goal of therapy is to increase blood pressure and maintain adequate perfusion, allowing nutrient and oxygen delivery to vital organs. Norepinephrine, phenylephrine, dopamine, epinephrine, and vasopressin are five vasopressors available in the ...
Rycerz Anthony M - - 2012
Negative pressure wound therapy (NPWT) is a widely accepted and effective treatment for various wound types, including complex wounds. Negative pressure with instillation was initially used as a gravity-fed system whereby reticulated, open-cell foam in the wound bed was periodically exposed to cycles of soaking with instillation solution followed by ...
Paulis Ludovit - - 2012
Although various effective treatments for hypertension are available, novel therapies to reduce elevated blood pressure, improve blood-pressure control, treat resistant hypertension, and reduce the associated cardiovascular risk factors are still required. A novel angiotensin-receptor blocker (ARB) was approved in 2011, and additional compounds are in development or being tested in ...
van den Bulck Rosine - - 2012
Since the introduction of negative pressure wound therapy in combination with reticulated open cell foam (NPWT/ROCF) in 1997, the clinical and economic benefits of this therapy have been showed in several randomised-controlled studies. This article describes the clinical application of a new portable NPWT unit. The V.A.C.Via™ Therapy System (KCI ...
Bertog Stefan C - - 2012
Systemic hypertension is a major burden to the individual and society. Its association with major adverse cardiac and cerebral events and favorable effects of antihypertensive therapy are undisputed. However, despite multidrug therapy, blood pressures are frequently suboptimally controlled. Moreover, adverse drug effects often interfere with patients' lifestyles and affect compliance. ...
Judd Eric - - 2012
Cardiovascular-related morbidity and mortality is linked to hypertension with proportional gains in cardiovascular risk factor reduction with the lowering of blood pressure. Clinical trial data has shown that attaining goal blood pressure requires, for most patients, at least two antihypertensive medications, with a significant proportion requiring regimens of three or ...
Müller Patrick P Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany. - - 2013
We aimed to characterize different cellular effects of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin 1 (AT1) receptor blockers (ARBs) as mono- or combination therapy in cardiac pressure overload. Methods and C57B1/6 mice received either the ACEI ramipril (2.5 mg/kg body weight), the ARB telmisartan (20 mg/kg body weight), or the ...
Schwartzenberg Shmuel - - 2012
The purpose of this study was to compare hemodynamic responses to vasodilator therapy in patients with heart failure (HF) and preserved ejection fraction (HFpEF) versus HF and reduced ejection fraction (HFrEF). There is no proven therapy for HFpEF. In the absence of data, medicines with established benefit in HFrEF such ...
Sato Nobuyuki - - 2012
Angiotensin receptor blockers (ARBs) with calcium channel blockers (CCBs) or diuretics are a widely used combination therapy for hypertensive patients. The present study aimed to determine which combination was better for elderly hypertension patients aged ≧ 65 years.We designed a multicentre, randomized, open-label, parallel comparison study. Hypertensive outpatients aged ≧ ...
Madej Andrzej - - 2012
Introduction: There is a growing body of data concerning significant interactions between markers of inflammation and cardiovascular diseases such as hypertension accompanied by elevated levels of plasma C-reactive protein (CRP). Therefore CRP is thought to be an independent risk factor of cardiovascular diseases. Material/Methods: The aim of this study was ...
Alnima Teba - - 2012
In the past few years, novel accomplishments have been obtained in carotid baroreflex activation therapy (BAT) for the treatment of resistant hypertension. In addition, this field is still evolving with promising results in the reduction of blood pressure and heart rate. This overview addresses the latest developments in BAT for ...
Maeda Akinobu - - 2012
Recent guidelines recommend combination antihypertensive therapy to achieve the target blood pressure (BP) and to suppress target organ damage. This study aimed to examine the beneficial effects of combination therapy with candesartan and amlodipine on BP control and markers of target organ function in Japanese essential hypertensive patients (N = ...
Malmsjö Malin - - 2012
Negative pressure wound therapy (NPWT) is commonly used in the continuous mode. Intermittent pressure therapy (IPT) results in faster wound healing, but it often causes pain. Variable pressure therapy (VPT) has therefore been introduced to provide a smooth transition between 2 different pressure environments, thereby maintaining the negative pressure environment ...
Kelly Aaron S - - 2012
The authors hypothesized that carvedilol controlled-release plus lisinopril combination therapy (C+L) would increase endothelial function and decrease oxidative stress to a greater extent than hydrochlorothiazide plus lisinopril combination therapy (H+L) in obese patients with hypertension. Twenty-five abdominally obese patients (aged 54.4±7.3 years; 14 women) with hypertension/prehypertension were enrolled in a ...
Mark Sharayne - - 2012
The use of pulmonary artery catheterization (PAC) has declined secondary to associated complications and lack of demonstrable efficacy in the inpatient setting. Few studies have been published on the use of PAC in nonacute heart failure (HF) patients. The purpose of this study was to review the use of PAC ...
Buckley Benjamin R - - 2011
The use of CO(2) for the preparation of value-added compounds has dramatically increased due to increased global warming concerns. We herein report an electrochemical cell containing a copper cathode and a magnesium anode that effectively converts epoxides and carbon dioxide to cyclic carbonates under mild electrochemical conditions at atmospheric pressure.
Kobayashi Hiroshi - - 2011
To compare the intraocular pressure lowering effect of adjustable sutures and laser suture lysis for trabeculectomy in eyes with primary open angle glaucoma. Fifty patients with primary open angle glaucoma were studied. Eyes were assigned randomly to either trabeculectomy augmented with mitomycin C with adjustable sutures or with laser suture ...
Loh Siew Yim - - 2011
Introduction Chronic pressure at work has debilitating impact on healthcare employers (e.g. reduced productivity, high costs, poor patient care) and on female healthcare employees (e.g. sickness, dysfunction). This paper highlights relationship at work as the key occupational source of work-stress which is organisational in nature. Methods A cross-sectional study (n = 230) ...
Sendelbach Sue - - 2011
The authors describe a pressure ulcer prevention program implemented across a large healthcare system in Minnesota. An interprofessional team of representatives from 10 hospitals developed a bundle of interventions directed at measurement standardization, provider education, patient/family education and point-of-care resources for providers, timely nutritional assessment, and a novel Skin Day ...
Kobayashi Hiroshi - - 2011
To study any correlation between a short-term change in conjunctival hyperemia severity and the intraocular pressure-lowering effect induced by latanoprost. A 114 patients (56 females and 58 males) with open-angle glaucoma or ocular hypertension were studied. Their mean age was 60.9±15.0 years (range, 25 to 87 y). The primary outcome ...
Miller Garfield - - 2011
To report a case of late subconjunctival bleb leak, and its management to preserve vision and achieve optimal pressure control in a patient with advanced glaucoma, a 3+ Seidel positive bleb leak, and hypotony maculopathy in the better-seeing eye. Case Report. Shutdown of the earlier trabeculectomy site with a scleral ...
Quan Susan Y - - 2010
BACKGROUND: A new pathophysiologic mechanism has been proposed that indicates that periorbital port-wine birthmarks (PWBs) serve as alternate collateral blood passageways when orbital venous drainage is impaired. The occlusion of such collateral venous channels could, therefore, potentially exacerbate impaired ocular venous flow and trigger the development or worsening of glaucoma ...
Suić Smiljka Popović - - 2010
An open label, multi-center, 6 months observational study of new fixed combination (travoprost 0.004%/timolol 0.5%), in order to evaluate both efficacy (intraocular pressure lowering) and tolerability (patient and investigator satisfaction) of two dosing regimens--evening (PM) and morning (AM). After screening for enrollment, to 40 patients (79 eyes with primary open ...
Yamamoto Loren G - - 2010
The measurement of intraocular pressure is perhaps the most important clinical parameter contributing to the diagnosis of glaucoma. This report describes the most commonly used methods of tonometry (to measure intraocular pressure). Considering the common options of Goldmann applanation tonometry (GAT), Schiotz tonometry (ST), and Tono-Pen tonometry (TP), the TP ...
Toris Carol B - - 2010
OBJECTIVE: To assess aqueous humor dynamics in pigment dispersion syndrome (PDS). METHODS: Four groups of age-matched participants included 2 experimental groups with PDS (PDS with ocular hypertension [PDS-OHT], 17 eyes; PDS without ocular hypertension [PDS-ONT], 18 eyes) and 2 control groups without PDS (OHT, 18 eyes; ONT, 18 eyes). Assessments ...
Waseem Muhammad - - 2010
OBJECTIVE: To determine the frequency of raised intraocular pressure (IOP) after Nd: YAG laser posterior capsulotomy and its association with the energy used with raised versus normal intraocular pressure in pseudophakes. STUDY DESIGN: Comparative, cross-sectional study. PLACE AND DURATION OF STUDY: Ophthalmology Department, PNS Shifa Hospital, Karachi, from August 2008 ...
Liu Pu P Department of Biochemistry and Molecular Biology, University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, - - 2010
Studies of Lmx1b have shown that it is required for anterior segment formation during embryonic development and that reduction of Lmx1b may contribute to elevated intraocular pressure in the adult. However, whether Lmx1b is required for formation of anterior segment tissues that are associated with regulation of intraocular pressure has ...
Rathinam S R - - 2010
PurposeTo report the occurrence of spontaneous hyphaema and acute ocular hypertension in four patients with severe lens-induced anterior uveitis.MethodsRetrospective case series.ResultsFour patients with mature cataract developed severe acute, unilateral, anterior uveitis associated with spontaneous hyphaema formation and acutely elevated intraocular pressure. None of the patients had a history of trauma ...
Draeger Jorg - - 2010
Hans Goldmann in 1958 emphasized the importance of the diurnal curve of intraocular pressure for very early detection of glaucoma. He stressed from the investigations of Leydhecker (1959) that there is a 10-year interval between early detection of chronic glaucoma and the first signs of neuronal defects or even later, ...
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