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Yamabe Hirotatsu - - 2014
CO2 geosequestration in deep aquifers requires the displacement of water (wetting phase) from the porous media by supercritical CO2 (non-wetting phase). However, the interfacial instabilities, such as viscous and capillary fingerings, develop during the drainage displacement. Moreover, the burst-like Haines jump often occurs under conditions of low capillary number. To ...
Williams Duane C DC From the *Division of Pediatric Critical Care, Duke Children's Hospital, Durham, NC; † Department of Perfusion, Duke University Hospital, Durham, NC; ‡ Department of Respiratory Care, Duke University Hospital, Durham, - - 2014
Hemolysis can occur as a consequence of extracorporeal membrane oxygenation (ECMO) and is associated with increased mortality and morbidity. Shear stress generated by flow through the circuit and oxygenator is believed to cause ECMO-induced hemolysis. We hypothesize that either a smaller dimension oxygenator or an in-line hemofilter will increase ECMO-associated ...
Moses Kayla L KL The University of - - 2014
While there is an increased prevalence of stroke at altitude in individuals who are considered to be low-risk for thrombotic events, it is uncertain how venous thrombi reach the brain. The patent foramen ovale (PFO) is a recruitable intracardiac shunt between the right and left atrium. We aimed to determine ...
Ebert Thomas J TJ From the Department of Anesthesiology, Medical College of Wisconsin and VA Medical Center, Milwaukee, - - 2014
Effective O2 delivery and accurate end-tidal CO2 (ETCO2) sampling are essential features of nasal cannulae (NCs) in patients with compromised respiratory status. We studied 4 NC designs: bifurcated nasal prongs (NPs) with O2 delivery and CO2 sensing in both NPs (Hudson), separate O2/CO2 NPs (Salter), and CO2 sensing in NPs ...
Longhini Federico F Department of Translational Medicine, Eastern Piedmont University 'A. Avogadro', Novara, - - 2014
Background: Neurally adjusted ventilatory assist (NAVA) is a novel mode of ventilation that has been demonstrated to improve infant-ventilator interaction, compared to the conventional modes in retrospective and short-term studies. Objectives: To prospectively evaluate the physiologic effects of NAVA in comparison with pressure-regulated volume control (PRVC) in two nonrandomized 12-hour ...
Torres Marta M CIBER de Enfermedades Respiratorias, Bunyola, - - 2014
Hypoxia can be damaging either because cells are directly sensitive to low oxygen pressure in their local microenvironment and/or because they are exposed to circulating factors systemically secreted in response to hypoxia. The conventional hypoxia model -breathing hypoxic air- does not allow to distinguish between these local and systemic effects. ...
Frånberg Oskar O Environmental Physiology Unit at the School of Technology and Health, Royal Institute of Technology KTH, Stockholm, - - 2014
Frånberg O, Loncar M, Larsson Å, Örnhagen H, Gennser M. A metabolic simulator for unmanned testing of breathing apparatuses in hyperbaric conditions. Aviat Space Environ Med 2014; 85:1139-44. A major part of testing of rebreather apparatuses for underwater diving focuses on the oxygen dosage system. A metabolic simulator for testing ...
Sehlin Maria M Department of Surgical and Perioperative Sciences, Anesthesiology and Intensive Care Medicine, Umeå University, Umeå, - - 2014
Sehlin M, Brändström H, Winsö O, Haney M, Wadell K, Öhberg F. Simulated flying altitude and performance of continuous positive airway pressure devices. Aviat Space Environ Med 2014; 85:1092-9. Continuous positive airway pressure (CPAP) is used in air ambulances to treat patients with impaired oxygenation. Differences in mechanical principles between ...
Alansari Mariam A - - 2014
A 70-year-old man underwent total hip replacement surgery under general anesthesia, endotracheal intubation, and controlled ventilation, with the patient in left lateral position. Intraoperatively, the patient was hemodynamically stable, with a normal range of pulse, ECG trace, oxygen saturation as measured by pulse oximetry (Spo2), and end-tidal CO2 (etco2). Five ...
Gilbert-Kawai Edward T ET University College London Centre for Altitude Space and Extreme Environment Medicine, UCLH NIHR Biomedical Research Centre, Institute of Sport and Exercise Health, London, United Kingdom; University College London Division of Surgery and Interventional Science, Royal Free Hospital, London, United Kingdom; University College Hospital London NIHR Biomedical Research Centre, London, United Kingdom; - - 2014
Anecdotal evidence surrounding Tibetans' and Sherpas' exceptional tolerance to hypobaric hypoxia has been recorded since the beginning of high-altitude exploration. These populations have successfully lived and reproduced at high altitude for hundreds of generations with hypoxia as a constant evolutionary pressure. Consequently, they are likely to have undergone natural selection ...
Mellor Adrian A 1 Defence Medical Services , Whittington Barracks, Lichfield, United Kingdom - - 2014
Abstract Mellor, Adrian, Christopher Boos, David Holdsworth, Joe Begley, David Hall, Andrew Lumley, Anne Burnett, Amanda Hawkins, John O'Hara, Stephen Ball, and David Woods. Cardiac biomarkers at high altitude. High Alt Med Biol 15:000-000, 2014.-Background: Classically, biomarkers such as the natriuretic peptides (NPs) BNP/NT-proBNP are associated with the diagnosis of ...
Kubesch N N Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain Universitat Pompeu Fabra (UPF), Barcelona, Spain Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain - - 2014
Short-term exposure to traffic-related air pollution (TRAP) has been associated with adverse cardiovascular outcomes. Physical activity (PA) in polluted air may increase pollutant uptake and increase these effects. Crossover real-world exposure study in 28 healthy participants comparing systolic (SBP) and diastolic blood pressure (DBP) responses to four different exposure scenarios: ...
Doorduin Jonne - - 2014
IntroductionDelivering synchronous assist during non-invasive ventilation (NIV) is challenging with flow or pressure controlled ventilators, especially in patients with chronic obstructive pulmonary disease (COPD). Neurally adjusted ventilatory assist (NAVA) uses diaphragm electrical activity (EAdi) to control the ventilator. We evaluated patient-ventilator interaction in patients with COPD during NIV with pressure ...
Santhanam Manikandan M Microbial Corrosion and Bioenvironmental Engineering, Central Electrochemical Research Institute (CSIR-CECRI), Karaikudi, 630 006, India, - - 2014
The textile dyeing industry produces large volumes of wastewater during dyeing processes where the major step includes the color removal and COD removal. In the present study, the combined electrooxidation process and a novel biological degradation at high compressed gas pressure were studied. The removal of color in the real ...
D'Angelo Olivia M OM From the Department of Anesthesia, Critical Care, and Pain Medicine, Carl Rosow Clinical Research Center, Massachusetts General Hospital, Boston, Massachusetts (O.M.D., D.D.-G., J.C.P.S., C.G., N.M., M.J.M., E.P., C.R., M.E.); Department of Speech, Language, and Swallowing Disorders, Massachusetts General Hospital, Boston, Massachusetts (D.N.); and Universitätsklinikum Essen, Klinik für Anästhesie und Intensivmedizin, Essen, Germany - - 2014
Coordination between breathing and swallowing helps prevent aspiration of foreign material into the respiratory tract. The authors examined the effects of anesthesia and hypercapnia on swallowing-breathing coordination. In a randomized controlled crossover study, general anesthesia with propofol or sevoflurane was titrated using an up-down method to identify the threshold for ...
Galster Kellen T KT Albany Medical College, Albany, New York; University of Nevada, Department of Emergency Medicine, Las Vegas, - - 2014
Postobstructive pulmonary edema (POPE)-also referred to as negative pressure pulmonary edema-occurs with deep inspiration against a closed glottis or obstructed airway. The result can be life threatening, however, most cases have a self-limited presentation and resolve with supportive care. Our aim was to critically evaluate a previously unreported mechanism in ...
Neary Joseph M JM Integrated Livestock Management, Department of Clinical Sciences,College of Veterinary Medicine and Biomedical Sciences, Colorado State University,Fort Collins, 1678 Campus Delivery, Colorado - - 2014
Domestic cattle have limited cardiopulmonary reserve for their body size and oxygen requirements. Therefore, it is plausible that impaired alveolar-arterial gas exchange may be detrimental to energetically expensive traits such as milk production which, like all aerobic processes, requires oxygen. The degree of alveolar-arterial oxygen transfer impairment can be determined ...
Hillestad V V KG Jebsen Cardiac Research Center, University of - - 2014
In patients, an association exists between pulmonary diseases and diastolic dysfunction of the left ventricle (LV). We have previously shown that alveolar hypoxia in mice induces LV diastolic dysfunction and that mice exposed to hypoxia have increased levels of circulating interleukin-18 (IL-18), suggesting involvement of IL-18 in development of diastolic ...
Britton Tyler T From the CSTARS Cincinnati (T.B., J.E., D.R.); and University of Cincinnati (T.C.B., R.D.B.), Cincinnati; and 711th Human Performance Wing Wright-Patterson Air Force Base (H.O.), Dayton, - - 2014
Ascent to altitude results in the expansion of gases in closed spaces. The management of overinflation of the endotracheal tube (ETT) cuff at altitude is critical to prevent mucosal injury. We continuously measured ETT cuff pressures during a Critical Care Air Transport Team training flight to 8,000-ft cabin pressure using ...
Blakeman Thomas T From the University of Cincinnati (T.Bl., R.B.), Cincinnati, Ohio; and United States Air Force (T.Br., - - 2014
Aeromedical transport of critically ill patients requires continued, accurate performance of equipment at altitude. Changes in barometric pressure can affect the performance of mechanical ventilators calibrated for operation at sea level. Deploying ventilators that can maintain a consistent tidal volume (VT) delivery at various altitudes is imperative for lung protection ...
Taylor Christopher N CN Creighton University School of Medicine, Omaha, - - 2014
We compared current Centers for Disease Control and Prevention surveillance criteria with the newer adult screening criteria (ASC) for identifying pediatric ventilator-associated pneumonia (VAP). Possible cases of VAP identified by ASC (n = 17) and cases of VAP identified by the older current surveillance criteria (n = 15) are comparable, but only ...
Blake Denise F DF Emergency Department, The Townsville Hospital, Townsville, Queensland, School of Marine and Tropical Biology, James Cook University, Townsville, IMB 23, Emergency Department, 100 Angus Smith Drive, The Townsville Hospital, Douglas, Queensland, Australia, 4814, Phone: +61-(0)7-4433-1111, Fax: +61-(0)7-4433-2901, E-mail: - - 2014
Current guidelines for transcutaneous oximetry measurement (TCOM) for the lower limb define tissue hypoxia as a transcutaneous oxygen partial pressure < 40 mmHg. Values obtained with some newer machines and current research bring these reference values into question. To determine 'normal' TCOM values for the lower limb in healthy, non-smoking ...
Schreier David A DA University of Wisconsin - - - 2014
Chronic hypoxia causes chronic mountain sickness through hypoxia-induced pulmonary hypertension (HPH) and increased hematocrit. Here, we investigated the impact of increased hematocrit and HPH on RV afterload via pulmonary vascular impedance. Mice were exposed to chronic normobaric hypoxia (10% oxygen) for 10 (10H) or 21 days (21H). After baseline hemodynamic ...
MacIntyre Neil R NR Division of Pulmonary and Critical Care Medicine, Duke University Medical Center, Durham, North Carolina. - - 2014
Oxygen is essential for normal aerobic metabolism in mammals. Hypoxia is the presence of lower than normal oxygen content and pressure in the cell. Causes of hypoxia include hypoxemia (low blood oxygen content and pressure), impaired oxygen delivery, and impaired cellular oxygen uptake/ utilization. Many compensatory mechanisms exist at the ...
Wang Jen-Chun JC Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, - - 2014
Rescuers that undergo acute ascent without acclimatization can experience acute mountain sickness. Although performing cardiopulmonary resuscitation (CPR) for a short period requires intensive effort at sea level, performing CPR at high altitude is even more exhausting and can endanger the rescuer. Therefore, we conducted a pilot study to compare the ...
Reper P P Critical Care Department, Queen Astrid Hospital and Free University of Brussels, Brussels, Belgium. Electronic address: - - 2014
Several biological markers of lung injury are predictors of morbidity and mortality in patients with acute respiratory distress syndrome (ARDS). Some lung-protective ventilation strategies, such as low tidal volume, are associated with a significant decrease in plasma biomarker levels compared to the high tidal volume ventilation strategy. The primary objective ...
Cavalcante Ricardo de Souza RD From the Departamento de Doenças Tropicais, Faculdade de Medicina de Botucatu, UNESP - Universidade Estadual Paulista , Botucatu, São Paulo State , - - 2014
Abstract Imipenem-resistant Acinetobacter baumannii (IRAB) is a major threat for critically ill patients, including those admitted to burn units. Recent studies have suggested that colonization pressure (the proportion of patients or patient-days harbouring the pathogen of interest) is an important driver of the risk for acquisition of multidrug-resistant organisms. With ...
Edsberg Laura E LE Laura E. Edsberg, PhD, Director, Center for Wound Healing Research, Natural & Health Sciences Research Center, Associate Professor Natural Sciences Department, Daemen College, Amherst, New York. Diane Langemo, PhD, RN, FAAN, Adjunct Faculty, University of North Dakota College of Nursing, Grand Forks. Mona Mylene Baharestani, PhD, APN, CWON, FACCWS, Associate Chief, Wound Care & Research Programs, James H. Quillen Veterans Affairs Medical Center, Johnson City (Mountain Home), Tennessee, and Clinical Associate Professor, Quillen College of Medicine, Department of Surgery, Johnson City, Tennessee. Mary Ellen Posthauer, BS, RDN, President, MEP Healthcare Dietary Services, Inc, Evansville, Indiana. Margaret Goldberg, MSN, RN, CWOCN Wound Care Consultant, Delray Wound Treatment Ctr, Delray Beach, - - 2014
In the vast majority of cases, appropriate identification and mitigation of risk factors can prevent or minimize pressure ulcer (PU) formation. However, some PUs are unavoidable. Based on the importance of this topic and the lack of literature focused on PU unavoidability, the National Pressure Ulcer Advisory Panel hosted a ...
Bassareo Pier Paolo PP Pier Paolo Bassareo, Giuseppe Mercuro, Department of Medical Sciences "Mario Aresu", University of Cagliari, Cagliari 09042, - - 2014
A large number of adults worldwide suffer from essential hypertension, and because blood pressures (BPs) tend to remain within the same percentiles throughout life, it has been postulated that hypertensive pressures can be tracked from childhood to adulthood. Thus, children with higher BPs are more likely to become hypertensive adults. ...
Pekin Burak K BK Division of Applied Plant Ecology, Institute for Conservation Research, San Diego Zoo Global, Escondido, California, United States of - - 2014
Ungulates exert a strong influence on the composition and diversity of vegetation communities. However, little is known about how ungulate browsing pressure interacts with episodic disturbances such as fire and stand thinning. We assessed shrub responses to variable browsing pressure by cattle and elk in fuels treated (mechanical removal of ...
McGee Maria P MP Plastic and Reconstructive Surgery Research, Wake Forest University School of Medicine, Winston-Salem, North - - 2014
Thermal injury disrupts fluid homeostasis and hydration, affecting hemodynamics and local interstitial fluid-driving forces, leading rapidly to edema. This study explores local mechanisms in vivo, after deep partial-thickness burns in the dermal matrix. Heat-damaged skin was obtained from pig corpses, byproducts of unrelated burn treatment protocols approved by the Institutional ...
Zhu Jinlong J 1] LANSCE, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA [2] National Lab for Condensed Matter Physics, Institute of Physics, CAS, Beijing, 100190, - - 2014
Materials with zero/near zero thermal expansion coefficients are technologically important for applications in thermal management and engineering. To date, this class of materials can only be produced by chemical routes, either by changing chemical compositions or by composting materials with positive and negative thermal expansion. Here, we report for the ...
Yuan Bao B State Key Laboratory of Superhard Materials, Jilin University, Changchun 130012, - - 2014
A method for performing simultaneous measurements of the electrical resistivity and the Seebeck coefficient at high pressure and high temperature (HPHT) in cubic multi-anvil apparatus is described. For high pressure and high temperature measurements, a four-probe arrangement is used to measure the electrical resistivity and two pairs of chromel-alumel type ...
Ren Haitao H Department of Burns and Wound Center, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People's Republic of - - 2014
We present two typical cases of severe complications (sepsis and hemorrhage) after negative pressure wound therapy (NPWT) in burned patients. Necrotic tissues in some deep burn wounds are difficult to judge correctly and remove thoroughly. An electrically burned blood vessel looks "intact" but can easily break. Necrotic tissue or injured ...
Moraes Davi J A DJ Department of Physiology, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, - - 2014
The respiratory modulation of sympathetic activity relies on the balance between excitatory and inhibitory inputs from the brainstem respiratory network to presympathetic neurons of the rostral ventrolateral medulla. This central respiratory-sympathetic contributes for the generation of respiratory-related rhythmical oscillations in heart rate and arterial pressure levels, whose functional effects on ...
Dion Joanna M JM Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital and The Ohio State University 700 Children's Drive, Columbus 43205, Ohio, - - 2014
Managing ventilation and oxygenation during laparoscopic procedures in severely obese patients undergoing weight loss surgery presents many challenges. Pressure-controlled ventilation, volume-guaranteed (PCV-VG) is a dual-control mode of ventilation and an alternative to pressure (PC) or volume (VC) controlled ventilation. PCV-VG features a user-selected tidal volume target, that is auto-regulated and ...
Tomiyama Yoshinobu Y Division of Surgical Center, Tokushima University Hospital, the University of - - 2014
Tension pneumothorax is a rare but potentially life-threating complication of laparoscopic fundoplication. Electrocardiogram (ECG) changes may be used in the diagnosis of intraoperative tension pneumothorax. This case study examines a pediatric patient who underwent laparoscopic fundoplication. Sudden decreases in oxygen saturation were observed during dissection, although the patient's decrease in ...
Diogo Lucilia N LN Centro de Estudos de Doenças Crónicas, CEDOC, NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa Lisboa, - - 2014
Sleep apnea/hypopnea disorders include centrally originated diseases and obstructive sleep apnea (OSA). This last condition is renowned as a frequent secondary cause of hypertension (HT). The mechanisms involved in the pathogenesis of HT can be summarized in relation to two main pathways: sympathetic nervous system stimulation mediated mainly by activation ...
Jameel Mohammad Nurulqadr MN Departments of Medicine, Radiology, the Center for Magnetic Resonance Research, and University of Minnesota Health Sciences Center, University of Minnesota, Minneapolis, Minnesota, United States of - - 2014
Decrease of ambient oxygen level has been used in myocytes culture experiments in examining the responsiveness to stress secondary to hypoxia. However, none of these studies measure the myocytes oxygenation levels resulting in ambiguity as to whether there is insufficient oxygen delivery. This study examined the hypothesis that at a ...
Flamme Ingo I Cardiology/Hematology, Acute Care Research, Global Drug Discovery, Bayer Pharma AG, Wuppertal, - - 2014
Oxygen sensing by hypoxia-inducible factor prolyl hydroxylases (HIF-PHs) is the dominant regulatory mechanism of erythropoietin (EPO) expression. In chronic kidney disease (CKD), impaired EPO expression causes anemia, which can be treated by supplementation with recombinant human EPO (rhEPO). However, treatment can result in rhEPO levels greatly exceeding the normal physiological ...
Atiyeh B S BS Division of Plastic and Reconstructive Surgery, Department of Surgery, American University of Beirut Medical Center (AUBMC), Beirut, - - 2013
Hypertrophic burn scars pose a challenge for burn survivors and providers. In many cases, they can severely limit a burn survivor's level of function, including work and recreational activities. A widespread modality of prevention and treatment of hypertrophic scarring is the utilization of pressure garment therapy (PGT). Despite the magnitude ...
Gustafson J J Division of Synchrotron Radiation Research, Lund University, Box 118, SE-221 00 Lund, - - 2013
We have studied the oxidation of CO over Rh(100) using high pressure x-ray photoelectron spectroscopy under CO and O2 pressures ranging from 0.01 to 1 mbar. The results show a very low or no conversion for the CO covered surface found at low temperatures, while the activity rises slightly when the ...
Persson Bo N J - - 2013
In a recent work Gotsmann and Lantz have observed that the thermal interface conductivity for a nano-sized nominal contact area is proportional to the normal contact pressure in a wide pressure range, with a prefactor which is typically ∼10(3) higher than observed for the same materials at the macroscale. Here ...
Chapman A J - - 2013
A 52-year-old Hispanic male was transported to the emergency department after sustaining severe bilateral lower extremity burns in an electroplating factory. His examination revealed circumferential burns to the lower extremities with spotting in the perineum. The epidermis was stained green and sloughed off with gentle pressure. The underlying dermis was ...
Hao Changchun - - 2013
The interactions between 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and palmitic acid (PA) in mixed monolayers were investigated through surface pressure measurements, fluorescence microscopy (FM) and atomic force microscopy (AFM). The miscibility of two components and the interactions between DOPC and PA in the mixed monolayers were accessed by analyzing surface pressure (π)-area (A) ...
Sanchez-Sanchez Manuel - - 2013
The use of urinary output and vital signs to guide initial burn resuscitation may lead to suboptimal resuscitation. Invasive hemodynamic monitoring may result in over-resuscitation. This study aimed to evaluate the results of a goal direct burn resuscitation protocol that used standard measures of mean arterial pressure (MAP) and urine ...
Jung Joo Young - - 2013
Porous network structures (e.g. metal-organic frameworks, MOFs) show considerable potential in dethroning monoethanol amine (MEA) from being the dominant scrubber for CO2 at the fossil-fuel-burning power generators. In contrast to their promise, structural stability and high-pressure behavior of MOFs are not well documented. We herein report moisture stability, mechanical properties ...
Hu Quan - - 2013
Excessive inflammation and high vasopermeability can lead to blood volume loss and tissue edema, which can affect the resuscitation and prognosis for serious burn patients. In this experiment, we investigated the effect of PNU-282987, an α7 nicotine cholinergic receptor agonist on the hemodynamic parameters and survival rate by inhibiting vasopermeability ...
Tailakh Ayman A College of Nursing, Sultan Qaboos University, Muscat, Oman. - - 2013
Hypertension (HTN) is a major risk factor for heart disease, which is the leading cause of death in the United States. Hypertension detection and blood pressure (BP) control are critically important for reducing the risk of myocardial infarction and strokes. Although there are more than 3.5 million Arab Americans in ...
Macintyre Lisa - - 2013
Pressure garments are used in the treatment of hypertrophic scarring following serious burns. The use of pressure garments is believed to hasten the maturation process, reduce pruritus associated with immature hypertrophic scars and prevent the formation of contractures over flexor joints. Pressure garments are normally made to measure for individual ...
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