Search Results
Results 251 - 300 of 2608
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Dimeo Fernando - - 2012
Regular physical exercise is broadly recommended by current European and American hypertension guidelines. It remains elusive, however, whether exercise leads to a reduction of blood pressure in resistant hypertension as well. The present randomized controlled trial examines the cardiovascular effects of aerobic exercise on resistant hypertension. Resistant hypertension was defined ...
Johnson D M - - 2012
INTRODUCTION: Evaluation of drug-related effects on cardiovascular function is part of the core battery described in the ICH S7A guideline. Anaesthetized guinea-pigs are an excellent model for the evaluation of drug-induced prolongation of ventricular repolarization; however less information is available regarding other cardio-haemodynamic parameters in this model. The current study ...
Singleton Thomas A - - 2012
The photo-induced isomerisation and thermal back relaxation of an azobenzene-functionalized polymer poly(disperse red 1 acrylate) were investigated at increasing external pressures up to 1.5 GPa inside a diamond-anvil spectroscopic cell. The thermal cis-trans isomerisation was monitored by laser pump-probe spectroscopy, which demonstrated an increase in the half-life of the isomerisation ...
Wu Shouling - - 2012
OBJECTIVES: This study aimed to determine the occurrence of cardiovascular (CV) events in a prehypertensive Chinese population. METHODS: Participants meeting the JNC 7 diagnostic criteria for prehypertension (n=30,027) and ideal blood pressure (n=15,614) were enrolled in this prospective, observational cohort. New CV events were collected during follow-up of 38-53months (mean ...
Mick Eric E Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA. - - 2013
Compared to children, adults with ADHD are at greater risk for developing adverse cardiovascular related outcomes and, if treated, may be likely to carry a greater burden of exposure to stimulant medications. The goal of this report is to critically review the available literature relevant to the cardiovascular safety of ...
Zepeda Ramiro J - - 2012
Oxidative stress and endothelial dysfunction have been associated with essential hypertension (EH) mechanisms. The purpose of this study was to evaluate the effect of carvedilol and nebivolol on the oxidative stress-related parameters and endothelial function in patients with EH. The studied population included 57 patients, either sex, between 30 and ...
Clayton H M - - 2012
The objectives of this study were to measure forces and pressure profiles when riding with a conventional saddle compared to bareback riding. An electronic pressure mat was used to compare contact area, mean total force and pressure variables for one rider riding seven horses at sitting trot with a conventional ...
Bor-Seng-Shu Edson - - 2012
Object In recent years, the role of decompressive craniectomy for the treatment of traumatic brain injury (TBI) in patients with refractory intracranial hypertension has been the subject of several studies. The purpose of this review was to evaluate the contribution of decompressive craniectomy in reducing intracranial pressure (ICP) and increasing ...
Russold Elena - - 2012
Objective  To compare tidal volume estimations obtained from Respiratory Ultrasonic Plethysmography (RUP) with simultaneous spirometric measurements in anaesthetized, mechanically ventilated horses. Study design  Prospective randomized experimental study. Animals  Five experimental horses. Methods  Five horses were anaesthetized twice (1 week apart) in random order in lateral and in dorsal recumbency. Nine ventilation ...
Gassara Fatma - - 2012
Lignin quantification in apple pomace residues was carried out using a microwave oven to replace traditional refluxing during the mild acidolysis step to augment the selectivity of this step towards cleavage of lignin-carbohydrate bonds and to reduce the time needed to quantify lignin. The pressure, temperature and time were optimized ...
Dragoumanos Vasileios - - 2012
OBJECTIVE: The objective was to evaluate whether passive leg raising during cardiopulmonary resuscitation in a porcine model of prolonged ventricular fibrillation improves hemodynamics, return of spontaneous circulation, 24-hour survival, and neurological outcome. METHODS: Ventricular fibrillation was induced in 20 healthy Landrace/Large White piglets, which were subsequently left untreated for 8 ...
Vernay Michel - - 2012
OBJECTIVE:: Dietary recommendations to reduce blood pressure (BP) have been widely disseminated. We investigated associations between dietary intake and BP in a national sample of adults living in France. METHODS:: The survey included 1968 18-74-year-old participants in the French Nutrition and Health Survey (Etude Nationale Nutrition Santé), a cross-sectional national ...
Jeppesen Jørgen L - - 2012
BackgroundIn a large collaborative study (n > 50,000), common variants in the natriuretic peptide (NP) genes were found to be associated with circulating NP levels and also with blood pressure (BP) levels based on office BP measurements (OBPMs). It is unknown if determining an individual's BP by 24-h ambulatory BP ...
Shukla Akash - - 2012
Transient lower esophageal sphincter relaxation (tLESR) and decreased basal lower esophageal sphincter (LES) pressure are postulated mechanisms of gastroesophageal reflux (GER). There is conflicting evidence on the effect of carbonated drinks on lower esophageal sphincter function. This study was conducted to assess the effect of a carbonated beverage on tLESR ...
Delerme Samuel - - 2012
BACKGROUND: Transcutaneous carbon dioxide pressure (PtcCO(2)) has been suggested as a noninvasive surrogate of arterial carbon dioxide pressure (PaCO(2)). Our study evaluates the reliability of this method in spontaneously breathing patients in an emergency department. PATIENTS AND METHODS: A prospective, observational study was performed in nonintubated dyspneic patients who required ...
Lin Aaron C W - - 2012
BACKGROUND:: Central arterial pressure is a better predictor of adverse cardiovascular outcomes than brachial blood pressure, but noninvasive measurement by applanation tonometry is technically demanding. METHOD:: Pulsecor R6.5 is a novel device adapted from a standard sphygmomanometer which estimates the central aortic pressure from analysis of low-frequency suprasystolic waveforms at ...
Rodrigues Sergio L - - 2012
BackgroundObesity has been described as a predictor of cardiovascular mortality, and some studies have reported an association with obesity and increased aortic stiffness. Other studies have not identified obesity to be an independent risk factor. Therefore, the purpose of our study was to determine the association between aortic stiffness and ...
Bosker Fokko J - - 2012
Genetic and environmental contributions to urinary excretion rates of norepinephrine (U(NE)V) and epinephrine (U(E)V) and their association with blood pressure (BP) were investigated in 91 African American (mean age, 17.3±2.6 years) and 101 European American (mean age, 18.7±3.4 years) mono- and di-zygotic twins. Genetic modeling was performed using Mx software. ...
Ilies C - - 2012
BACKGROUND: /st>The intensified use of spinal anaesthesia (SPA) for Caesarean section significantly contributed to a decreased maternal mortality and morbidity. Nevertheless, one of the major side-effects is hypotension after SPA with potential negative effects on the fetus. Owing to discontinuous oscillometric measurements (non-invasive arterial pressure, NIAP), hypotensive episodes may be ...
Iwamoto Yumiko - - 2012
OBJECTIVE: Cardiovascular diseases are associated with impaired flow-mediated vasodilation (FMD) and increase in carotid intima-media thickness (IMT). Both FMD and IMT are independent predictors for cardiovascular outcomes. When measuring FMD and nitroglycerine-induced vasodilation in the brachial artery, IMT can also be simultaneously assessed in the same brachial artery. The purpose ...
McBride William T - - 2012
OBJECTIVE: Negative-pressure ventilation (NPV) by external cuirass (RTX; Deminax Medical Instruments Limited, London, UK) in intubated patients after cardiac surgery improves hemodynamics measured by pulmonary artery catheter (PAC)-based methods with increased cardiac output (CO) and stroke volume (SV) without changing the heart rate (HR). The less-invasive pressure recording analytical method ...
Ulusoy Sukru - - 2012
In addition to high blood pressure (BP), BP variability has recently also been shown to increase cardiovascular events. The purpose of this study was to compare the effect of a fixed-dose combinations (FDCs) of valsartan/amlodipine and a valsartan- and amlodipine-free drug combination on 24-h BPV. A total of 85 patients ...
Bayarjargal Lkhamsuren - - 2012
The high-pressure behavior of KIO(3) was studied up to 30 GPa using single crystal and powder x-ray diffraction, Raman spectroscopy, second harmonic generation (SHG) experiments and density functional theory (DFT)-based calculations. Triclinic KIO(3) shows two pressure-induced structural phase transitions at 7 GPa and at 14 GPa. Single crystal x-ray diffraction at 8.7(1) GPa was ...
Gatti Renata R - - 2012
Renin-angiotensin and kallikrein-kinin systems are interconnected, regulating blood pressure homeostasis. We have demonstrated the interactions among polymorphisms of the angiotensinogen (AGT) and endothelial nitric oxide synthase (NOS3) genes and conventional risk factors affecting the hypertension occurrence. Individuals were recruited (n=192) and classified into hypertensive (HG; n=140) and normotensive (NG; n=52) ...
Ali Sadeeq - - 2012
The interface pressure between the residual limb and prosthetic socket has a significant effect on an amputee's satisfaction and comfort. Liners provide a comfortable interface by adding a soft cushion between the residual limb and the socket. The Dermo and the Seal-In X5 liner are two new interface systems and, ...
Le-Ha Chi - - 2012
Aims: Lifestyle behaviours established during adolescence may adversely affect blood pressure (BP) and contribute to gender differences in cardiovascular risk in adulthood. We aimed to assess the association of health behaviours with BP in adolescents, using data from the Western Australian Pregnancy (Raine) Study.Methods: Cross-sectional analysis on 1248 Raine Study ...
Sia Sheau Fung - - 2012
BACKGROUND:: Maintaining flow in a newly established high flow bypass into the intracranial circulation may be threatened by low blood pressure. OBJECTIVE:: To identify mean arterial blood pressure below which early graft failure may ensue. METHODS:: Computational fluid dynamic blood flow simulation and Doppler ultrasound derived velocities were combined to ...
Soydinc Hatice Ender - - 2012
Data about circadian blood pressure (BP) in normotensive patients with gestational diabetes mellitus (GDM) are lacking. Thus, we sought to compare dipper and nondipper circadian variation of BP profile between normotensive women complicated with GDM and normal pregnant women. Forty-two women with GDM and 33 normal uncomplicated pregnant women who ...
Behrens A - - 2012
OBJECTIVE: The aim of this study was to investigate whether pulsations measured in the brain correspond to those measured in lumbar space, and subsequently whether lumbar punctures could replace invasive recordings. METHODS: In ten patients with normal pressure hydrocephalus, simultaneous recordings of the intracranial pressure (ICP; intraparenchymal) and lumbar pressure ...
Eguchi Kazuo - - 2012
BACKGROUNDS: Although the European Society of Hypertension International Protocol for the validation of blood pressure (BP) measuring devices has simplified the validation protocol, it is still not feasible for use in routine clinical practice. OBJECTIVES: We sought to devise a method for validating individual home blood pressure (HBP) monitors that ...
Rinehart Joseph - - 2012
OBJECTIVE: The authors compared the performance of a group of anesthesia providers to closed-loop (Learning Intravenous Resuscitator [LIR]) management in a simulated hemorrhage scenario using cardiac output monitoring. DESIGN: A prospective cohort study. SETTING: In silico simulation. PARTICIPANTS: University hospital anesthesiologists and the LIR closed-loop fluid administration system. INTERVENTIONS: Using ...
Zweifel Christian - - 2012
BACKGROUND:: It has been postulated that Gosling's pulsatility-index (PI) assessed with transcranial Doppler (TCD) has a diagnostic value for non-invasive estimation of intracranial pressure (ICP) and cerebral perfusion pressure (CPP). OBJECTIVE:: To revisit this hypothesis using a database of digitally stored signals from a cohort of head injured patients. METHODS:: ...
Sun Jing - - 2012
AIMS: Orthostatic intolerance (OI) is a common clinical problem; however, effective and applicable clinical prevention/treatment is limited. The aim of this study was to investigate whether electroacupuncture (EA) is a novel effective treatment in attenuating OI in healthy individuals.METHODS AND RESULTS: This study used a randomized, controlled, crossover design using ...
McBride William T - - 2012
OBJECTIVE: Negative-pressure ventilation (NPV) by external cuirass (RTX; Deminax Medical Instruments Limited, London, UK) in intubated patients after cardiac surgery improves hemodynamics measured by pulmonary artery catheter (PAC)-based methods, with an increased cardiac output (CO) and stroke volume (SV), without changing the heart rate (HR). The less-invasive pressure recording analytical ...
Mizokami Fumihiro - - 2012
A pressure ulcer is a localised injury of the skin and underlying tissue that usually develops over a bony prominence. A decrease in the pressure over the bony prominence effectively prevents pressure ulcers; however, no studies have systematically assessed the physical properties of existing pressure ulcers. To characterise pressure ulcers, ...
Klingenberg Claus - - 2012
ObjectiveThe 2010 ILCOR neonatal resuscitation guidelines do not specify appropriate inflation times for the initial lung inflations in apnoeic newborn infants. The authors compared three ventilation strategies immediately after delivery in asphyxiated newborn lambs.DesignExperimental animal study.SettingFacility for animal research.SubjectsEighteen near-term lambs (weight 3.5-3.9 kg) delivered by caesarean section.InterventionsAsphyxia was induced ...
Gonzales Joshua F - - 2012
Rationale: Inspiratory rise time and cycling criteria are important settings in pressure support ventilation. The purpose of this study was to investigate the impact of minimum and maximum rise time and inspiratory cycling criteria settings on six new generation ventilators. Our hypothesis is: there will be a difference in the ...
Hu Gufeng - - 2012
A novel side-hole two-core microstructured optical fiber (STMOF) is proposed for hydrostatic pressure sensing. The two solid fiber cores are surrounded by a few small air holes and two large air holes, and are separated by one small air hole in the center of the cross section of the STMOF. ...
Fox Karin A - - 2012
OBJECTIVE: The objective of the study was to determine whether perinatal nicotine exposure adversely affects cardiovascular health in adulthood. STUDY DESIGN: C57Bl/6J female mice were randomized to 200 μg/mL nicotine in 2% saccharin or 2% saccharin alone from 2 weeks before breeding until weaning. Offspring weight, vital signs, and carotid ...
Lee I-Te - - 2012
BACKGROUND: Hypertension is a prevalent condition that is closely associated with chronic complications in patients with diabetes. Fixed-dose combination therapy is currently recommended for the treatment of hypertension due to the advantage of reducing the pill burden. However, the effects of combination therapy may be diverse because of the different ...
Borrone Roberto - - 2012
Purpose. To investigate whether there is agreement between intraocular pressure (IOP) readings in the supine position at 6 am upon awaking (before getting out of bed) and the IOP at 8 am, also measured in supine position after remaining 30 minutes in this position. Methods. In a sample of 50 ...
Mossello Enrico - - 2012
BACKGROUND: Older subjects living in nursing homes (NHs) show a high prevalence of multimorbidity, disability, and cognitive impairment. The clinical meaning of arterial hypertension (AH) in this population is unclear, and few studies have adopted ambulatory blood pressure monitoring (ABPM) with this purpose. The aims of the study were to ...
Gritti Fabrice - - 2012
The theory of gradient elution usually assumes a constant flow rate. This works extends it to gradients performed under constant pressure drop and variable flow rates. The peak capacity is derived under both constant flow rate and constant pressure gradient chromatography by integrating the rate of increase of the peak ...
Sato Shinji - - 2012
A small-sized sonochemical reactor in which the absolute value of the sound pressure amplitude can be estimated from the vibration velocity of the transducer was investigated. The sound pressure distribution in the reactor and the relationship between the vibration velocity and the sound pressure amplitude were derived through Helmholtz wave ...
Klarenbeek Pim - - 2013
Enlarged Virchow-Robin spaces (EVRS) are considered to be a sign of cerebral small vessel disease. Hypertension is an important risk factor for cerebral small vessel disease, whereas ambulatory blood pressure (BP) is the strongest predictor of hypertension-related brain damage. However, the association between ambulatory BP levels and EVRS has never ...
Lavrentieva A - - 2012
OBJECTIVE: The purpose of this study was to assess the usefulness of stroke volume variations to monitor the early fluid resuscitation in mechanically ventilated burn ICU patients. METHODS AND RESULTS: Data of 29 burn patients (APACHE II - 9.8±3.6, SAPS II - 29±5, TBSA - 39.5±14) were prospectively included in ...
Loenneke Jeremy P - - 2012
Skeletal muscle may be viewed as an endocrine organ that releases numerous factors with the potential to influence vascular tone. Previous cross-sectional studies have shown an inverse relationship between muscle mass and arterial stiffness. We examined the relationship between muscle mass, arterial pressure in the aorta and brachial artery, and ...
Laurent Alexandra - - 2012
The distribution of pressure coefficient formed when the fluid contacts with the kayak oar-blade is not been studied extensively. The CFD technique was employed to calculate pressure coefficient distribution on the front and rear faces of oar-blade resulting from the numerical resolution equations of the flow around the oar-blade in ...
Wikstrom Erik A - - 2012
The purpose of this investigation was to determine if stereotypical patterns of gait initiation are altered in those with post-traumatic ankle osteoarthritis. Ten subjects: five with unilateral ankle osteoarthritis and five uninjured controls participated. Subjects completed the SF-36 and Ankle Osteoarthritis Scale to quantify self-reported disability as well as 10 ...
Alperin N - - 2012
BACKGROUND AND PURPOSE:Impaired CSF homeostasis and altered venous hemodynamics are proposed mechanisms for elevated pressure in IIH. However, the lack of ventricular expansion steered the focus away from CSF homeostasis in IIH. This study aims to measure intracranial CSF volumes and cerebral venous drainage with MR imaging to determine whether ...
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