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Lacourcière Yves Y Hypertension Unit, Centre Hospitalier Universitaire de Québec, Québec, Canada. - - 2013
The aim of this review was to compare telmisartan and valsartan in the treatment of hypertension. PubMed searches were conducted to identify randomized trials (n = 14) comparing the two agents, alone or combined with hydrochlorothiazide. With one exception, all studies with blood pressure reduction as primary endpoint showed significantly ...
Luo Wenshu - - 2012
BACKGROUND: Few prospective studies on association between waist circumference and hypertension have taken account of the dynamic change of WC, which caused by lifestyle modification. METHODS: After a baseline investigation, we conducted the first and the second follow-up assessments for subjects after 2 and 5years, respectively. The difference value (D-value, ...
Pariaut R - - 2012
BACKGROUND: The impact of pulmonary hypertension (PH) on right ventricular systolic function is difficult to assess. Tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measurement of right ventricular systolic function and a strong predictor of outcome in human PH patients. HYPOTHESIS/OBJECTIVES: Determine a reference range for TAPSE in healthy ...
Terai Naim - - 2012
Purpose:  To investigate the effect of caffeine on retinal vessel diameter before and during flicker light stimulation in young healthy subjects. Methods:  Seventeen healthy subjects (mean age: 29.6 ± 3.73 years, range: 22-35 years) were included in this study. The diameter of retinal vessels was measured continuously with the retinal vessel analyzer (RVA) before ...
Scallan Joshua P - - 2012
We tested the responses of single, isolated lymphangions to selective changes in preload and the effects of changing preload on the response to an imposed afterload. The methods used were similar to those described in our companion paper. Step-wise increases in input pressure (P(in); preload) over a pressure range between ...
Lima Eric G EG Cooper Union, Department of Mechanical Engineering, 41 Cooper Square, New York, NY 10003, USA. - - 2012
In this study, we explored the application of lipid-shelled, gas-filled microbubbles as a method for creating on-demand microporous hydrogels for cartilage tissue engineering. The technique allowed for homogenous distribution of cells and micropores within the scaffold, increasing the absorption coefficient of large solutes (70kDa dextran) over controls in a concentration-dependent ...
Underwood Patricia C PC Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, RFB 386, Boston, Massachusetts 02115, USA. - - 2012
It is assumed that in individuals with type 2 diabetes mellitus (T2DM), blood pressure sensitivity to salt intake and the frequency of a low renin state are both increased compared with the nondiabetic population. However, studies supporting these assumptions may have been confounded by participant inclusion criteria, and study results ...
Gons Rob A R - - 2012
Vascular factors play a role in the etiology of Alzheimer's disease (AD), presumably due to emergence of white matter lesions. However, important white matter structures involved in the etiology of AD, including the corpus callosum (CC), remain invariably free from macroscopical white matter lesions, although loss of microstructural integrity assessed ...
Foltz Wibke U - - 2012
Pressure overload is associated with cardiac hypertrophy and electrical remodeling. Here, we investigate the effects of the antioxidant N-acetylcysteine (NAC) on the cellular cardiac electrophysiology of female Sprague-Dawley rats with ascending aortic stenosis (AS). Rats were treated with NAC (1 g/kg body weight) or control solution 1 week before the intervention and ...
Cong Li - - 2012
PURPOSE:: The purpose of this study was to determine whether a continuous quality improvement program would reduce pressure ulcer prevalence. SUBJECTS AND SETTING:: The study sample comprised 2913 patients who were used as a baseline comparison group and 3019 patients who acted as the intervention group. The research setting was ...
Berkenstadt Haim - - 2012
Cardiac arrest in the parturient is often fatal, but appropriate resuscitation in this special situation may save the lives of the mother and/or unborn baby. Concern has arisen as to application of recommended techniques for resuscitation in the obstetric patient. The Israel Board of Anesthesiology has incorporated simulation assessment into ...
Larsen Thomas - - 2012
Low 25-hydroxy-vitamin D (25(OH)D) levels are inversely related to blood pressure (BP) and have been associated with incident hypertension. In people living at northern latitudes diminished cholecalciferol synthesis in the winter increases the risk of vitamin D deficiency. We wanted to test the hypothesis that daily cholecalciferol supplementation in the ...
Mei Hao - - 2012
The authors conducted a genome-wide linkage scan and positional association analysis to identify the genetic determinants of salt sensitivity of blood pressure (BP) in a large family-based, dietary-feeding study. The dietary intervention was conducted among 1,906 participants in rural China (2003-2005). A 7-day low-sodium intervention was followed by a 7-day ...
Bhatnagar Vibha - - 2012
Blood pressure is a complex quantitative trait with a strong genetic component. In this study, we leveraged the Veterans Affairs electronic medical record system to explore the relationship between Paraoxonase 1 (PON1)-108 C/T (rs705379) and mean arterial blood pressure (MAP). Outpatient blood pressure data over an approximate 8-year period was ...
Koebnick Corinna - - 2012
Background/Aims Extreme obesity is an increasing concern in pediatric care but its association with pre-hypertension and hypertension are not clear. The objective of the present study is to assess the prevalence of different stages of pre-hypertension and hypertension in the pediatric population, to investigate potential disparities, and to evaluate the ...
Chalidis Byron E - - 2012
Tourniquet application is a widely accepted adjuvant technique in extremity surgery. The purpose of this prospective, randomized trial was to evaluate the effect of cuff width on skeletal muscle ischemia-reperfusion injury. A 2- or 4-cm wide curved tourniquet cuff was applied around the midthigh of 36 New Zealand White rabbits ...
Pal G K - - 2012
Prehypertension has recently been observed as a potent cardiovascular risk factor. Though prehypertension has a strong familial predisposition, the pathophysiological mechanisms that cause its progression to prehypertension in normotensive sibling of hypertensive parents have not yet been fully elucidated. Therefore, the present study was conducted in normotensive and prehypertensive sibling ...
Eriksson Marie - - 2012
The Hawksley random-zero sphygmomanometer (random-zero) has been used widely in epidemiological observation studies. This study compares blood pressure measurements using the random-zero with measurements using an automated oscillometric device and suggests a correction of the automated oscillometric measurements to enable comparisons of blood pressure levels over time. The northern Sweden ...
Fikri-Benbrahim Narjis - - 2012
Purpose The effect of a protocol-based pharmacist intervention on blood pressure (BP) control among treated hypertensive patients who use community pharmacies was studied. Methods A quasi-experimental study with a control group was conducted at 13 community pharmacies in Jaén and Granada in Spain. Hypertensive patients over age 18 years who ...
Lewis Nina C S - - 2012
Tolerance time to a standardized orthostatic stressor is markedly reduced in normotensive individuals in the morning. However, the physiological mechanisms that underpin this phenomenon are unknown. The purpose of this study was to examine the role of α(1)-adrenergic activity on orthostatic tolerance and associated cardiorespiratory and cerebrovascular responses, and to ...
Sperl-Hillen Joann - - 2012
Background/Aims Guidelines for blood pressure (BP) treatment thresholds and goals have been derived from measurements obtained in research clinics (RC), but few studies have compared BP measurements obtained in RC and routine primary care practice (PCP) settings, where decisions about BP treatment occur. Aims To compare BP obtained from RC ...
Seo Seung Ree - - 2012
Background  β-Cyclodextrin (βCD) xerogel containing silk fibroin (SF) was prepared, and the efficacy of the xerogel for a pressure sore developed on the back of an ICR mouse was investigated. Materials and methods  Tosyl βCD was conjugated to polyethyleneimine (PEI), and the βCD residues were cross-linked in an aqueous phase ...
Bader Kenneth B - - 2012
The amplitude of the acoustic pressure required to nucleate a gas or vapor bubble in a fluid, and to have that bubble undergo an inertial collapse, is termed the inertial cavitation threshold. The magnitude of the inertial cavitation threshold is typically limited by mechanisms other than homogeneous nucleation such that ...
Adji Audrey - - 2012
Noninvasive applanation tonometry studies of the brachial and radial artery pressure waves show that the arterial pulse is substantially amplified between the brachial and radial sites. Brachial tonometry waveforms have also been used to calibrate carotid tonometry waves as a measure of central pressure in major clinical trials. These trials ...
Fonseca-Reyes Salvador - - 2012
When blood pressure (BP) is taken for the first time, it should be measured in both arms; follow-up measurements should be taken in the arm with the highest BP. However, in clinical practice, this recommendation is rarely followed. Identify the degree of differences in BP between the right and the ...
Derosa G - - 2012
Abstract Objective: to evaluate if there is a correlation between some new emerging biomarkers, such as lipoprotein(a) (Lp[a]), apo(a) isoform phenotyping, soluble advanced glycation end products (sRAGE), soluble CD40 ligand (sCD40L), serum myeloperoxidase (MPO), and cardiovascular risk stratification. Research design and methods: 300 patients were enrolled in this open label, ...
Sakabe Kazumi - - 2012
Background/Aims: It is important to control blood pressure as well as to control blood glucose for the prevention of diabetic nephropathy. However, to our knowledge, there are no reports investigating which blood pressure, including morning, evening and clinic, is more closely associated with albuminuria and whether one measurement is sufficient ...
O'Connor Patrick - - 2012
Background/Aims The benefits of early hypertension (HT) control in patients with diabetes (DM) may vary by degree of BP control achieved in the year after HT onset. Methods Retrospective cohort study, of 13,480 DM who met study criteria for new onset HT based on blood pressure (BP) measurements, ICD-9 HT ...
Chin Kong Yien - - 2012
Devices based on the arterial volume clamping technique, such as the Finapres, Portapres or Finometer, have become the methods of choice in studies requiring continuous noninvasive recordings of arterial blood pressure (BP). Most validation studies have used intravascular BP measurements in the radial artery as a reference. We tested the ...
Javed Shazia - - 2012
: Hypertension is a disease that affects approximately one billion people worldwide. It is estimated that as much as 5 to 30% of the hypertensive population are resistant. We present the first case of a hypertensive patient on quadruple medical therapy whose blood pressure was controlled with DBS of the ...
Duranton Frédérique - - 2012
The interaction of salt (0%, 1.5%, and 3% in the final product) and a high-pressure treatment (500 MPa, 20 °C, 6 min) was investigated using pork biceps femoris muscle. The Warner-Bratzler shear force and the water holding capacity (WHC) were assessed and linked to the microstructure evaluation by environmental scanning ...
O'Connor Patrick - - 2012
Background/Aims The benefits of early hypertension (HT) control in patients with diabetes (DM) may vary by degree of BP control achieved in the year after HT onset. Methods Retrospective cohort study, of 13,480 DM who met study criteria for new onset HT based on blood pressure (BP) measurements, ICD-9 HT ...
Coelho Luís - - 2012
In this Letter, a hybrid interferometer for simultaneous measurement of the partial pressures of O<sub>2</sub> and CO<sub>2</sub> mixtures is reported. The sensing head consists in the combination of two interferometric structures, one a Fabry-Pérrot cavity and the other a modal interferometer. The intrinsic Fabry-Pérot was formed by splicing a single ...
Freer M - - 2012
A 41-year-old, obese, patient was admitted to Accident and Emergency with a history of leg cellulitis. A central line was inserted. Documented aspiration of blood from all lines, central venous pressure trace obtained and correct position noted on the chest X-ray (CXR). The patient became increasingly septic despite antibiotic therapy. ...
Hull James H - - 2012
BACKGROUND: Adults with cystic fibrosis (CF) have altered large artery haemodynamics which is associated with a persisting systemic inflammatory state. We hypothesized that a short-term intervention favorably influencing the inflammatory status may modify their haemodynamic state. METHODS: Adult patients with CF were studied immediately preceding and following 2weeks of intravenous ...
Navarro-Ripoll Ricard - - 2012
Endoscopic insufflation has been associated with marked increase in intra-abdominal pressure (IAP) and hemodynamic and respiratory changes during transgastric surgery. To investigate the hemodynamic and respiratory effects during intraperitoneal cavity exploration through 3 different natural orifice transluminal endoscopic surgery (NOTES) access locations compared with laparoscopy. Survival experiments using 40 female ...
Chen Lee Chuin - - 2012
Standard field desorption (FD) ionization is implemented under high vacuum condition. In this paper, non-vacuum FD is performed under a super-atmospheric pressure environment using untreated tungsten wires as FD emitter, and the ion source was coupled to a commercial linear ion trap mass spectrometer. The operating pressure of the ion ...
Folck Bruce - - 2012
Background/Aims The VDW Vitals Workgroup specifies data standards for the four traditional clinical vital signs (body temperature, blood pressure, respirations, heart rate) and other physiological measures that are collected routinely during clinic visits, such as height and weight. Data specifications changed considerably between the older Version 2, and the current ...
Durães-Carvalho Ricardo - - 2012
Exposure to high pressure is an efficient method of bacterial inactivation that is particularly important for reducing the microbial load present in foods. In this study, we examined the high pressure inactivation of Aeromonas hydrophila AH 191, a virulent strain that produces aerolysin, a cytotoxic, enterotoxic, and hemolytic toxin. High ...
Alipour Fariborz - - 2012
Pressure in the laryngeal ventricle was measured with a beveled needle connected to a pressure transducer in excised canine larynges. Air pressures within the ventricle were obtained for different adduction levels of the true vocal folds (TVFs), false vocal folds (FVFs), and subglottal pressures (Ps). Results indicated that the air ...
Oladapo O O - - 2012
Hypertension is a major challenge to public health as it is frequently associated with sudden death due to the silent nature of the condition. By the time of diagnosis, some patients would have developed target-organ damage (TOD) and associated clinical conditions (ACC) due to low levels of detection, treatment and ...
Han J-Y - - 2012
The purpose of this study was to assess the value of acoustic radiation force impulse (ARFI) for evaluating portal hypertension by correlating the elasticity of liver cirrhosis, as measured by ARFI, with haemodynamic indices measured by Doppler ultrasound. We evaluated the data of a total of 154 prospectively enrolled patients ...
Garcia-Espinosa Maria A - - 2012
Transgenic (mRen2)27 rats are hypertensive with impaired baroreflex sensitivity for control of heart rate compared with Hannover Sprague-Dawley rats. We assessed blood pressure and baroreflex function in male hemizygous (mRen2)27 rats (30-40 weeks of age) instrumented for arterial pressure recordings and receiving into the cisterna magna either an Ang-(1-7) fusion ...
Soller Babs R - - 2012
Hemorrhage is a major cause of soldier death; it must be quickly identified and appropriately treated. We developed a prototype patient monitor that noninvasively and continuously determines muscle oxygen saturation (SmO₂), muscle pH (pHm), and a regional assessment of blood volume (HbT) using near-infrared spectroscopy. Previous demonstration in a model ...
Mueller Genevieve R - - 2012
Noncompressible hemorrhage is the leading cause of preventable death caused by hemorrhage on the battlefield. Currently, there are no hemostatic agents with the ability to control noncompressible hemorrhage. A wound stasis dressing based upon rapidly expanding cellulose minisponges (MS) was developed and tested in a lethal noncompressible model in swine, ...
Taghavi Sharven S Department of Surgery, Temple University Hospital, Philadelphia, Pennsylvania 19140, - - 2012
Prehospital intubation does not appear to result in a survival advantage for patients experiencing penetrating trauma; yet, there is still resistance to the practice of "scoop and run" to speed access to advanced care. An animal model was used to determine whether intubation provides a survival advantage during potentially lethal ...
Aries Marcel J H MJ Academic Neurosurgery Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK. - - 2012
Guidelines for the management of traumatic brain injury (TBI) call for the development of accurate methods for assessment of the relationship between cerebral perfusion pressure (CPP) and cerebral autoregulation and to determine the influence of quantitative indices of pressure autoregulation on outcome. We investigated the relationship between slow fluctuations of ...
Aries Marcel J H MJ Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, and Neurosciences Critical Care Unit, Addenbrooke's Hospital, Cambridge, UK. - - 2012
We have sought to develop an automated methodology for the continuous updating of optimal cerebral perfusion pressure (CPPopt) for patients after severe traumatic head injury, using continuous monitoring of cerebrovascular pressure reactivity. We then validated the CPPopt algorithm by determining the association between outcome and the deviation of actual CPP ...
Webb David R DR Department of Cardiovascular Sciences, Leicester Royal Infirmary University of Leicester, Leicester, Bedfordshire, UK. - - 2012
South Asians migrating to Northern latitudes are more susceptible to premature cardiovascular disease (CVD) than expected for given levels of blood pressure. Vitamin D deficiency is common in this group and may play an important role mediating vascular wall senescence in response to central pressure effects. A cross-sectional association study. ...
Teperikidis Eleftherios E Drug Information Center, Synapse, Hellenic Pharmaceuticals and Services, Drug Information Division, Egnatias 117, Thessaloniki, 54635, Greece. - - 2012
A case of mild symptomatic hypotension after treatment with menaquinone (vitamin K(2)) is reported. A 62-year-old white man with a medical history of hyperlipidemia, coronary artery disease, and benign prostatic hyperplasia was started on a regimen of menaquinone 100 μg daily as a supplement to his medications for coronary artery ...
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