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Results 551 - 600 of 2582
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Lefebvre Jean-Claude - - 2012
PURPOSE: Providing mechanical ventilation is challenging at supra-atmospheric pressure. The higher gas density increases resistance, reducing the flow delivered by the ventilator. A new hyperbaric ventilator (Siaretron IPER 1000) is said to compensate for these effects automatically. The aim of this bench test study was to validate the compensation, define ...
Spence D - - 2012
OBJECTIVE: To compare blood pressure between 50-year-old adults who were born at term (37-42 weeks of gestation) with intra-uterine growth restriction (IUGR; birth weight <10th centile) and a control group of similar age born at term without IUGR (birth weight ≥10th centile). STUDY DESIGN: Controlled comparative study. METHODS: Participants included ...
Durukan Mine - - 2012
Objective. Isolated systolic hypertension (ISH) is generally encountered in elderly patients and there are scarce data regarding the renin-angiotensin-aldosterone system (RAAS) activity in patients with ISH. We aimed to determine the plasma renin activity (PRA), plasma aldosterone levels (PAL) and aldosterone/PRA ratio (PAL/PRA) in patients (age >50 years) with ISH ...
Fedecostante Massimiliano - - 2012
OBJECTIVE:: Evaluation of seasonal influences on ambulatory blood pressure monitoring (ABPM) values in a very large population living in a mild-climate geographic area. METHODS:: Among patients referred to our Hypertension Center between September 2002 and January 2011 with a reliable ABPM, we considered those in the two hottest (July and ...
Vinyoles Ernest - - 2012
Aim. To assess the variability and concordance of left ventricular hypertrophy electrocardiographic (LVH-ECG) criteria. Methods and Results. Convenience sampling of hypertensive subjects without coronary disease or bundle branch blocks. Two electrocardiograms (ECGs) were performed on each patient. Two investigators carried out two blind-readings of each ECG (Cornell and Sokolow-Lyon criteria). ...
Barnes Theresa T Institute of Chronic Disease and Ageing, Clinical Sciences Centre, Aintree University Hospital, Longmoor Lane, Liverpool, - - 2012
This study aims to examine the utility of von Willebrand factor (vWF) as a biomarker in lcSSc, in particular the ability of vWF to predict the future development of disease manifestations in this disease. vWFAg concentrations were measured in the serum of patients with lcSSc at baseline and at 3 ...
Mohanlal Viresh - - 2012
Blood pressure naturally rises with increasing age. The rate of change in blood pressure with age is regulated in part by genetic factors, but can also be altered through sustained dietary modification. Dietary approaches to modify blood pressure remain an important part of cardiovascular health promotion, which is especially important ...
Zimbarra Cabrita Inês - - 2012
AIMS: Transthoracic echocardiography is a useful technique for non-invasive detection of pulmonary arterial systolic pressure (PASP). Isovolumic relaxation time (IVRT) measured by Doppler tissue imaging (DTI) is a sensitive measurement of changes in pulmonary vasculature. Our aim was to validate IVRT in the echocardiographic assessment of pulmonary hypertension (PH) patients. ...
Bihari Shailesh - - 2012
INTRODUCTION: Potentially beneficial effects of positive end-expiratory pressure (PEEP) in patients with chronic obstructive pulmonary disease (COPD) must be balanced against further overinflation and increased alveolar dead space. Concurrent chronic heart failure (CHF) is common and can lead to changes in lung that can reduce the detrimental effects of PEEP. ...
Eide Macpherson James F - - 2012
Purpose. To present a unique case of a 65-year-old man using warfarin who presented with acute unilateral loss of vision due to hemorrhagic Descemet membrane detachment (DMD) with pupillary block and elevated intraocular pressure and its subsequent treatment and challenges. Method. Case report. Results. Clinical examination showed a visual acuity ...
Ahmad Nafees - - 2012
Rationale, aims and objectives  Existing literature suggests that doctors' poor adherence with guidelines is one of the major contributing factors to suboptimal control of hypertension. This study aims to evaluate doctors' adherence with Malaysian clinical practice guideline (CPG 2008) in a tertiary care hospital, and factors associated with guideline adherence ...
Sanders Joan E - - 2012
Residual limb volume may change after doffing, affecting the limb shape measured and used as a starting point for socket design. The purpose of this study was to compare residual limb fluid volume changes after doffing for different test configurations. The study was a repeated measures experimental design with three ...
Alvarez Jessica A - - 2012
Vitamin D reportedly influences vascular function, which is worse in African Americans (AAs) relative to European Americans (EAs). It is not clear if ethnic differences in 25(OH)D mediate differences in vascular function. This study examined the relationships of serum 25-hydroxyvitamin D (25(OH)D) with indicators of vascular function among healthy, young ...
Maas Jacinta J - - 2012
To assess the level of agreement between different bedside estimates of effective circulating blood volume-mean systemic filling pressure (Pmsf), arm equilibrium pressure (Parm) and model analog (Pmsa)-in ICU patients. Eleven mechanically ventilated postoperative cardiac surgery patients were studied. Sequential measures were made in the supine position, rotating the bed to ...
Satoh Daizoh - - 2012
Several reports in the literature have described the effects of positive end-expiratory pressure (PEEP) level upon functional residual capacity (FRC) in ventilated patients during general anesthesia. This study compares FRC in mechanically low tidal volume ventilation with different PEEP levels during upper abdominal surgery. Before induction of anesthesia (awake) for ...
Weber Thomas - - 2012
We recently developed a novel method for assessment of arterial wave reflections (ARCSolver method): based on adopted Windkessel methods, flow curves are estimated from pressure waveforms, and wave separation analysis is performed, yielding the amplitudes of the forward and backward waves. The aim of this study was to investigate their ...
Lee Alice - - 2012
The aim was to establish normative nasalance values for Irish English-speaking adults. Thirty men and 30 women with normal resonance read aloud 16 sentences from the Irish nasality assessment protocol, the Zoo passage, and the Rainbow passage. The speech samples were recorded using the Nasometer II 6400. Results of a ...
Ozarslan Nihal Gökbulut - - 2012
OBJECTIVE: This investigation was performed to compare the effects of inhalation agents on microcirculation in coronary artery bypass grafting (CABG) using orthogonal polarization spectral imaging. DESIGN: This prospective and randomized study was performed in patients scheduled for CABG surgery from March through September 2010. SETTING: Tertiary care university hospital. PARTICIPANTS: ...
Tan Isabella - - 2012
Arterial stiffness, as measured by aortic pulse wave velocity (PWV), is an independent marker of cardiovascular disease and events in both healthy and diseased populations. Although some cardiovascular risk factors, such as age and blood pressure, show a strong association with PWV, the association between heart rate (HR) and PWV ...
Bostick Adam W - - 2012
BACKGROUND: High-frequency oscillatory ventilation (HFOV) has been utilized as a rescue oxygenation therapy in adults with acute respiratory distress syndrome over the last decade. The HFOV oscillating piston can generate negative pressure during the exhalation cycle which has been termed active exhalation. We hypothesized that this characteristic of HFOV entrains ...
Tang Rui - - 2012
BACKGROUND: The accuracy of end-expiratory lung volume measurement by modified nitrogen washout/washin (EELV-nitrogen washout/washin) depends on the precise determination of carbon dioxide elimination (VCO₂), which is affected by alveolar dead space (VDalv). The purpose of this study was to investigate the influence of VDalv on EELV-nitrogen washout/washin. METHODS: Six piglets ...
Verdecchia Paolo - - 2012
We investigated the relationship between the day-night blood pressure (BP) dip and the early morning BP surge in an cohort of 3012 initially untreated subjects with essential hypertension. The day-night reduction in systolic BP showed a direct association with the sleep trough (r = 0.564; P < 0.0001) and the ...
Beard Daniel A - - 2012
ABSTRACT: BACKGROUND: Data on blood flow regulation, renal filtration, and urine output in salt-sensitive Dahl S rats fed on high-salt (hypertensive) and low-salt (prehypertensive) diets and salt-resistant Dahl R rats fed on high-salt diets were analyzed using a mathematical model of renal blood flow regulation, glomerular filtration, and solute transport ...
Jefferies Laura K - - 2012
High-pressure needleless injection (HPNI) is an emerging enhancing process where small-diameter, high-velocity bursts of liquid penetrate soft foods at pressures up to 69 MPa. The incidence and depth of translocated surface-inoculated E. coli O157 in HPNI-processed beef eye-of-round subprimal cuts was determined. HPNI translocated E. coli O157 from the surface ...
Pacella John J - - 2012
Objective:  We have shown that drag reducing polymers (DRP) enhance capillary perfusion during severe coronary stenosis and increase RBC velocity in capillaries, through uncertain mechanisms. We hypothesize that DRP decreases pressure loss from the aorta to the arteriolar compartment. Methods: Intravital microscopy of the rat cremaster muscle and measurement of ...
Lee Ting-Ting - - 2012
Pressure ulcers (a type of skin failure) have served as an indicator of care quality. The purpose of this study was to utilize data-mining techniques as a means of identifying risk factors related to different stages of pressure ulcers to demonstrate how this means of analysis might be used as ...
Kerkhof Gerthe F - - 2012
OBJECTIVE: To investigate the effect of preterm birth on risk factors for cardiovascular disease (CVD), independent of birth size. STUDY DESIGN: Observational study using data of 406 healthy participants aged 18-24 years, from the PROgramming factors for Growth And Metabolism and Prematurity and Small for Gestational Age studies. Associations between ...
Hoareau G L - - 2012
BACKGROUND: Brachycephalic dogs (BD) are prone to congenital upper airway obstruction (brachycephalic syndrome, BS). In humans suffering from sleep apnea, upper airway obstruction is known to cause hypertension. There is no information regarding the influence of BS in dogs on cardiorespiratory physiology. HYPOTHESIS: BD are prone to lower P(a) O(2) ...
Fazalbhoy Azharuddin - - 2012
We recently showed that acute muscle pain, induced by bolus intramuscular injection of hypertonic saline, causes a sustained increase in muscle sympathetic nerve activity (MSNA) and a modest increase in blood pressure and heart rate. However, it is not known whether long-lasting (tonic) pain - which more closely resembles chronic ...
Brosnan Robert J - - 2012
Objective  To test the hypothesis that hypercapnic hyperpnea produced using endotracheal insufflation with 5-10% CO(2) in oxygen could be used to shorten anesthetic recovery time in horses, and that recovery from sevoflurane would be faster than from isoflurane. Study design  Randomized crossover study design. Animals  Eight healthy adult horses. Methods  ...
Yin Rui-Xing - - 2012
BackgroundSex differences in hypertension are not well known. The present study was undertaken to detect the association of nine lipid-related gene polymorphisms and blood pressure variation beween men and women in the Bai Ku Yao population.MethodsGenotyping of ATP-binding cassette transporter A1 (ABCA-1) V825I, acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) rs1044925, low-density lipoprotein receptor ...
Cuspidi Cesare - - 2012
BackgroundThe relationship between high nocturnal blood pressure (BP), organ damage and the dipping/nondipping status is poorly defined. We investigated whether a consistent dipping/nondipping pattern defined on the basis of two 24-h ambulatory BP monitorings (ABPMs) is associated with subclinical organ damage in untreated hypertensive patients with elevated nighttime BP.MethodsAll subjects ...
Vigen Rebecca - - 2012
BackgroundMedication adherence and treatment intensification have been advocated as performance measures to assess the quality of care provided. Whereas previous studies have shown that adherence and treatment intensification (TI) of antihypertensive medications is associated with blood pressure (BP) control at the patient level, less is known about whether adherence and ...
Paglieri Cristina - - 2012
This study tested the association between cognitive functions, cerebrovascular damage, and cerebrovascular reactivity in 71 essential young hypertensives (age matched) and 22 normotensives (age matched). They underwent ambulatory blood pressure monitoring, neurocognitive tests, cerebral magnetic resonance, and transcranial Doppler. Twenty-three percent of patients showed more than 10 white matter lesions ...
Cicero A F G - - 2012
Our aim was to evaluate the predictors of Isoleucine-Proline-Proline/Valine-Proline-Proline (IPP-VPP) lactotripeptides (LTPs) antihypertensive effect in the context of a short-term large double-blind randomized clinical trial involving 164 pharmacologically untreated subjects in primary prevention for cardiovascular disease. When compared with the baseline, office systolic blood pressure (SBP) (-3.42 mm Hg, P ...
Cao Xia - - 2012
Mean platelet volume (MPV), an indicator of platelet activation, has been shown to be elevated in patients with hypertension. However, data available on the association between MPV level and prehypertension are limited. Prehypertension is also associated with an increase in cardiovascular morbidity and mortality. A cross-sectional study was performed among ...
Ahmad Hasan A - - 2012
Right heart failure from right ventricular (RV) pressure overload is a major cause of morbidity and mortality, but its mechanism is incompletely understood. We tested the hypothesis that right heart failure during 4 hours of RV pressure overload is associated with alterations of the focal adhesion protein talin, and that ...
Bell Emmy K - - 2012
Few studies have compared different blood pressure (BP) indexes for end-stage renal disease (ESRD) risk among individuals with chronic kidney disease. We examined the relationship between systolic BP (SBP), diastolic BP (DBP), pulse pressure (PP) and mean arterial pressure (MAP) and ESRD risk among 2,772 participants with an estimated glomerular ...
Wemmelund K B - - 2012
BACKGROUND: Although pleural effusion is a common complication in critically ill patients, detailed knowledge is missing about the haemodynamic impact and the underlining mechanisms. The aim of this study was to evaluate the haemodynamic effect of incremental pleural effusion by means of invasive haemodynamic parameters and transthoracic echocardiography. METHODS: This ...
Bertera Facundo Martín - - 2012
Cardiovascular effects and pharmacokinetics of nebivolol were assessed in spontaneously hypertensive rats (SHR) and Wistar Kyoto (WKY) animals. Male SH and WKY rats were treated with vehicle or nebivolol 0.3, 3, or 10 mg kg(-1) (i.v.) and effects on blood pressure (BP), heart rate, and blood pressure variability (BPV) were recorded. Plasma ...
Nazari Hossein - - 2012
BACKGROUND: To study intraocular pressure (IOP) alteration in healthy individuals following a rapid effortless increase in altitude from 1900 m above sea level (ASL) to 3740 m ASL. METHODS: Intraocular pressure, blood pressure, pulse rate, and arterial oxygen tension were determined in both eyes of healthy volunteers at the lower altitude. Participants ...
Wang Jen-Yu - - 2012
OBJECTIVE: To evaluate the cause-effect relationships between serum levels of uric acid (UA) and metabolic syndrome (MetS) in an adolescent-male cohort that was followed for 2.7 years. STUDY DESIGN: We enrolled male adolescents aged between 10 and 15 years at the baseline. A total of 613 subjects were divided into ...
Haham Michal - - 2012
We have previously introduced the potential of casein micelles (CM) as natural nanovehicles for hydrophobic nutraceuticals, e.g. vitamin D (VD) (E. Semo, E. Kesselman, D. Danino and Y. D. Livney, Food Hydrocolloids, 2007, 21, 936-942). The aims of the current study were to improve performance by adding an ultra-high-pressure homogenization ...
Jin Yuyan - - 2012
Treatment decisions for hypertension using sphygmomanometer based measurements and the current clinical practice paradigm do not account for the timing of blood pressure (BP) measurement. This study aimed to evaluate the clinical implications of discordance between measured and true BP, to quantify BP misclassification rate at a typical clinical visit ...
Pei Juan - - 2012
Background: Heart rate variability (HRV) is an useful noninvasive tool to assess autonomic nervous system (ANS) function and may provide an insight into the understanding of the role of ANS in the pathogenesis of blood pressure (BP) abnormality in euvolemic continuous ambulatory peritoneal dialysis (CAPD) patients. Methods: In this cross-sectional ...
Fan Xiao-Han - - 2012
An adenine insertion polymorphism in the 5' untranslated region of the endothelin-1 gene is functional and increases the expression of endothelin mRNA and protein in the insertion homozygote. In the present study we hypothesized that this functional polymorphism might be associated with hypertension and/or orthostatic hypotension. The adenine insertion polymorphism ...
Turner Barbara J - - 2012
Adopting features of the Chronic Care Model may reduce coronary heart disease risk and blood pressure in vulnerable populations. We evaluated a peer and practice team intervention on reduction in 4-year coronary heart disease risk and systolic blood pressure. A single blind, randomized, controlled trial in two adjacent urban university-affiliated ...
Carey Katherine M - - 2012
OBJECTIVE:To evaluate the efficacy and safety of the polypill for prevention of cardiovascular disease (CVD) and stroke and to present literature related to the polypill components (statin, aspirin, antihypertensive) for primary prevention of CVD and stroke.DATA SOURCES:A literature search was conducted in MEDLINE (1948-January 2011) and EMBASE (1974-January 2011) using ...
Demirel S - - 2012
OBJECTIVE: Impairment of baroreceptor sensitivity (BRS) has been shown to be associated with blood pressure instability after carotid endarterectomy (CEA). The aim of this study was to determine whether there is a difference in postoperative BRS changes following eversion CEA (E-CEA) and conventional CEA (C-CEA). METHODS: Sixty-four patients undergoing E-CEA ...
Vathesatogkit Prin - - 2012
OBJECTIVE:: Few data have linked socioeconomic status (SES) to incident hypertension, and little information on the relationship between SES and hypertension are available from developing countries. We thus investigated the long-term effects of SES on incident hypertension and changes in blood pressure in Thailand. METHODS:: In 1985, baseline data were ...
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