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Ma Fanyi F Department of Food and Nutrition Science, University of Reading, Whiteknights, Reading RG6 6AP, - - 2015
Gum arabic is widely used in the food industry as an additive, both as a thickener and an emulsifier. This study has compared the emulsification properties of two types of gums, KLTA (Acacia senegal) and GCA (Acacia seyal), both in their native/untreated forms and after exposure to high pressure (800MPa). ...
Moonen An A Department of Gastroenterology, Translational Research Center for Gastrointestinal Disorders (TARGID), University Hospital of Leuven, Catholic University of Leuven, Herestraat 49, Leuven 3000, - - 2014
The mechanical properties of the esophagogastric junction (EGJ) are of major importance for the competence of the EGJ. Although manometry reliably measures sphincter pressure, no information is provided on distensibility, a crucial determinant of flow across the EGJ. Recently, a new technique, impedance planimetry, was introduced allowing accurate measurement of ...
Rawstorne E E Heart of England NHS Foundation Trust, - - 2014
A 40 year old female with longstanding faecal incontinence and occasional symptoms of obstructive defecation was investigated with anorectal physiology, which demonstrated poor internal anal sphincter tone and poor external anal sphincter pressure responses and endoanal ultrasound studies which demonstrated an anterior sphincter defect.. A cloacal defect was diagnosed and ...
Sultana Razia - - 2014
Family is the smallest unit of people to share most of the lifestyle, environmental and genetic factors. They are likely to have similarity in many physiological and behavioural aspects. Therefore, we designed a protocol to test the effect of large rural Indian families living together (Kumbas), on blood pressure variability. ...
Xu Chen C aDepartment of Colorectal Surgery, Nankai University Affiliated Hospital bDepartment of Endocrinology, The Second Hospital of Tianjin Medical University, Tianjin, People's Republic of China cDivision of Digestive Diseases, The David Geffen School of Medicine at UCLA, Los Angeles, California, - - 2014
The aim of this study is to evaluate the three-dimensional anorectal pressure topography of normal healthy adults and patients with paradoxical puborectalis syndrome (PPS) using a novel three-dimensional high-resolution manometry (3D-HRM) of the anorectum. The 3D-HRM probe has a 6.4 cm long sensing segment that is composed of 256 independent ...
Ke Lei L 1 Laboratory of Medical Precision Engineering and Intelligent Systems, Department of Instrument Science and Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiaotong University, Shanghai - PR - - 2014
This paper presents some of the latest progress in the development of a novel artificial anal sphincter system (AASS) to treat severe fecal incontinence. We have redesigned and integrated an intelligent, remote-controlled artificial anal sphincter based on biological signal feedback mechanisms. The device consists of an external telemetry unit, an ...
Carrington E V EV GI Physiology Unit, The Wingate Institute of Neurogastroenterology, Barts and the London School of Medicine and Dentistry, London, UK; National Centre for Bowel Research and Surgical Innovation (NCRBSI), Barts and the London School of Medicine and Dentistry, London, - - 2014
High-resolution anorectal manometry (HRAM) is a relatively new method for collection and interpretation of data relevant to sphincteric function, and for the first time allows a global appreciation of the anorectum as a functional unit. Historically, traditional anal manometry has been plagued by lack of standardization and healthy volunteer data ...
Parangama Chatterjee C Department of Radiodiagnosis and Imaging, Christian Medical College, Vellore, Tamil Nadu, India. Electronic address: - - 2014
This study aims to determine if anal sphincter defects/thinning observed at endoanal ultrasound correlates with anal pressures recorded at anal manometry. A total of 30 consecutive patients with history suggestive of anal sphincter pathology underwent anal endosonography with documentation of internal and external sphincter defects/thinning. The same patients underwent anal ...
Ahmad Nafees N Hamdard University, Faculty of Pharmacy, Department of Pharmaceutics , New Delhi-110062 , India +91 11 26059688, +91 9818335148 ; - - 2014
Objective: Pathogenesis of anal fissure (AF) is associated with raised resting anal pressures (RAP) involving contraction of smooth muscle. Therefore, the drug delivery strategy should be customized to reduce this raised RAP. In this investigation, in order to achieve this task, a transdermal nanoemulsion (NE) gel of lercanidipine (LER) was ...
Broens Paul M A - - 2013
None of the current theories on fecal incontinence can explain fecal continence adequately. This study aims to evaluate the mechanism controlling fecal continence. Anal electrosensitivity, anorectal pressures, and rectal pressure volumetry tests were performed in 17 controls before and after superficial local anal anesthesia and in 6 controls before and ...
Ambartsumyan Lusine - - 2013
OBJECTIVES:The pathophysiology of fecal incontinence is not well understood. Standard or high-resolution anorectal manometry (ARM) provides simple two-dimensional (2D) intra-anal pressure measurements and do not identify radial asymmetry or localize abnormal sphincter function. 3D high-definition ARM (HDARM) has 256 pressure sensors distributed circumferentially and provides a detailed topographical and 3D ...
Latz Stefan - - 2013
Introduction: To evaluate the meaning of urodynamic parameters in patients with pouch incontinence. Materials and Methods: Thirteen urodynamic studies in patients with an ileal nipple as the efferent segment of an ileocecal pouch or ileum/ileocecal-augmented bladder were performed. The recorded parameters included pouch capacity, leak point pressure/volume, maximum pouch pressure, ...
Hotouras Alexander - - 2013
We read the article by Loganathan et al entitled "Prolonged Pudendal Nerve Terminal Motor Latency is Associated with Decreased Resting and Squeeze Pressures in the Intact Anal Sphincter" which suggests that unilateral or bilateral pudendal neuropathy is associated with reduced anorectal pressures in patients with an intact anal sphincter complex.(1) There ...
Vitton Véronique - - 2013
Our aim was to compare for the first time measurements obtained with water-perfused catheter anorectal manometry and 3-D high resolution manometry in patients with anorectal disorders. Consecutive patients referred to our centre for anorectal manometry (ARM) were recruited to undergo the two procedures successively. Conventional manometry was carried out using ...
Loganathan A - - 2013
To determine the contribution of the pudendal nerve to the anal continence mechanism by determining the correlation between pudendal nerve terminal motor latency (PNTML) and resting and squeeze anal canal pressures METHODS: 1051 patients were investigated with anorectal physiology studies between January 1998 and July 2010. Of these, 213 patients ...
Vitton Véronique - - 2013
AIM: 3-dimensional (3-D) anorectal high-resolution manometry (3D HRAM) is a new technique that can simultaneously provide physiological and topographic data. Our aim was to assess whether it can identify anal sphincter defects by comparing it with endoanal ultrasonography (EUS) considered as the gold standard. METHOD: An anal defect on 3D ...
Li Yuwei - - 2013
OBJECTIVES: The purpose of this study is to evaluate normal values and pressure morphology of three-dimensional high-resolution anorectal manometry (3D-HRM) in asymptomatic volunteers and to determine the relationship between objective measurable values, gender, and age. PATIENTS AND METHODS: Anorectal pressures and rectal sensation were evaluated in 110 asymptomatic volunteers (46 ...
Yamaguchi Izumi - - 2013
BACKGROUND: Although intersphincteric resection can avoid the need for permanent colostomy in patients with lower rectal cancer, it sometimes causes anal sphincter dysfunction, thus resulting in a lifelong, debilitating disorder due to incontinence of solid and liquid stool. The development of regenerative medicine could improve this condition by regenerating impaired ...
Patazca Eduardo - - 2013
Several studies have been published on the inactivation of bacterial spores by using high pressure processing in combination with heat. None of the studies investigated the effect of the packaging system or the pressurizing fluid on spore inactivation. The objective of this study was to select and validate an appropriate ...
Khaikin M - - 2013
BACKGROUND: Previous laboratory studies have shown that angiotensin II is produced locally in the rat internal anal sphincter causing potent contraction. The aim of this first human study was to evaluate the safety and manometric effects of topical application of captopril (an ACE inhibitor) on the resting anal pressure in ...
Quinn Martha - - 2013
PURPOSE: The traditional Brooke ileostomy removed the last 8-15 cm of the ileum due to concern of occurrence of terminal ileal Crohn's disease, vide infra the ileocolic sphincter was removed. Retaining all the terminal ileum has the potential of retaining the ileocolic sphincter. Our aim was to investigate whether a high-pressure ...
Martínez-Garzón Patricia - - 2013
A passive seismic monitoring campaign was carried out in the frame of a CO2-Enhanced Oil Recovery (EOR) pilot project in Alberta, Canada. Our analysis focuses on a two-week period during which prominent downhole pressure fluctuations in the reservoir were accompanied by a leakage of CO2 and CH4 along the monitoring ...
Damaser Margot S - - 2012
: Stimulation of the pudendal nerve or the anal sphincter could provide therapeutic options for fecal incontinence with little involvement of other organs. The goal of this project was to assess the effects of pudendal nerve and anal sphincter stimulation on bladder and anal pressures. : Ten virgin female Sprague ...
Hornung B R - - 2012
Anal acoustic reflectometry (AAR) is a reproducible technique providing a novel physiological assessment of anal sphincter function. It may have advantages over conventional anal manometry. The aims of this study were to determine the ability of AAR and anal manometry to identify changes in anal sphincter function in patients with ...
Alqudah M M - - 2012
Background  Ano-rectal disorders are common in the general population. Although they are not life threatening conditions, they do represent a social stigma and a reduced quality of life for the sufferer. The underlying physiology of muscle function contributing to ano-rectal competence is complex and there is room for a much ...
Salcedo Levilester - - 2012
OBJECTIVE.: Fecal incontinence reduces the quality of life of many women but has no long-term cure. Research on mesenchymal stem cell (MSC)-based therapies has shown promising results. The primary aim of this study was to evaluate functional recovery after treatment with MSCs in two animal models of anal sphincter injury. ...
Non Amy L AL Harvard Center for Population and Development Studies, Harvard University, Cambridge, MA 02138, USA. - - 2012
We assessed the relative roles of education and genetic ancestry in predicting blood pressure (BP) within African Americans and explored the association between education and BP across racial groups. We used t tests and linear regressions to examine the associations of genetic ancestry, estimated from a genomewide set of autosomal ...
Mahalingaiah L L Department of Dairy Technology, Dairy Science College, Karnataka Veterinary, Animal and Fishery Sciences University, Hebbal, 560 024 Bangalore, - - 2014
Kunda, an indigenous heat desiccated sweet product prepared from milk and added sugar, has a shelf-life of a few days under market conditions. In this study, effect of preservatives viz. potassium sorbate and nisin on the shelf-life of kunda stored at 30° and 5 °C was investigated. During storage, several changes ...
Bany Brent M - - 2012
The decrease in maternal blood pressure during early gestation is likely directed by signals from the conceptus but not the developing decidual tissue.
Ramesh Kumar - - 2012
Raised intracranial pressure is a life threatening condition; unless recognized and treated early, it may progress into herniation syndrome and death. Symptoms and signs are neither sufficiently sensitive nor specific, hence a high index of suspicion and vigilance are needed for early recognition. Immediate goal of management is to prevent ...
Araki Jun - - 2012
Colostomy is conventionally the only treatment for anal dysfunction. Recently, a few trials of anorectal transplantation in animals have been published; however, further development of this technique is required. Moreover, it is crucial to perform this research in dogs, which resemble humans in anorectal anatomy and biology. We designed a ...
Kutuzova Galina D GD Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706-1544, United - - 2012
Ocular hypertension is the greatest known risk factor for glaucoma that affects an estimated 70 million people worldwide. Lowering intraocular pressure (IOP) remains the mainstay of therapy in the management of glaucoma. By means of microarray analysis, we have discovered that 1α,25-dihydroxyvitamin D(3) (1α,25-(OH)(2)D(3)) regulates genes that are known to ...
Kung Jennifer - - 2011
Raman scattering and x-ray diffraction studies of CaSnO(3) perovskite were performed under high-pressure conditions. This high-pressure study was motivated by a recent theoretical study predicting a phase transition in CaSnO(3) from GdFeO(3)-type perovskite to CaIrO(3)-type structure occurred at 12 GPa. Despite no obvious structure change up to a pressure of 26 ...
Hillman Noah H - - 2011
The initiation of ventilation in preterm, surfactant-deficient sheep without positive end-expiratory pressure (PEEP) causes airway injury and lung inflammation. We hypothesized that PEEP and surfactant treatment would decrease the lung injury from initiation of ventilation with high tidal volumes. Fetal sheep at 128-day gestational age were randomized to ventilation with: ...
Sherlock C - - 2011
Although single layer techniques are preferred in man and small animals for small intestinal end-to-end anastomoses, double layer techniques are more popular in equine surgery. This study was undertaken to evaluate the ex vivo characteristics of 2 single layer anastomoses in comparison to the traditionally performed double layer anastomosis in ...
Martín-Rodríguez R - - 2011
Since the crystal-field strength at the Cr(3 + ) site is very close to the excited-state crossover (ESCO), this work investigates the optical properties of Cr(3 + )-doped Gd(3)Ga(5)O(12) (GGG) nanoparticles as a function of temperature and pressure in order to establish the effect of the ESCO on the optical ...
Silvestre Francisco-Javier - - 2011
To evaluate the efficacy and safety of the vasoconstrictor used in local anesthesia during dental extraction in controlled hypertensive patients. A prospective observational study was carried out in hypertensive patients (n=97) with a mean age of 60.45±9.60 years. The following parameters were monitored at three different timepoints (before the procedure, ...
Lam Bing - - 2011
OBJECTIVES: The purpose of this study is to evaluate the efficacy of oral appliance (OA) treatment for subjects with severe obstructive sleep apnea (OSA) and to determine the dental parameters associated with treatment outcomes. STUDY DESIGN: This study uses a prospective longitudinal design. METHODS: Consecutive Chinese subjects with severe OSA ...
Al-Zahrani M S - - 2011
This study was conducted to assess prevalence of hypertension and prehypertension in a sample of female dental patients. A total of 208 consecutive female patients aged ≥ 18 years provided information about sociodemographics, history of hypertension and other systemic diseases, antihypertension medication use and smoking history. Two blood pressure measurements ...
Venkatakrishnan Jaichandran - - 2011
Purpose. To report a case of pulmonary edema, in a child under general anesthesia, due to iatrogenic acute hypertensive crisis following instillation of 1 drop of 5% phenylephrine eyedrops. Methods. A 2-year-old boy was scheduled for examination of both eyes and enucleation of the left eye under general anesthesia. In ...
Engström Sevek - - 2011
There is consensus on the importance of early detection and treatment of high blood pressure. Dental care is one of few medical services to which a considerable proportion of the general population comes for regular check-ups. We tested the effects of blood pressure screening in dental care centres with subsequent ...
Nyrén Sven - - 2010
The underlying mechanism for the increased alveolar-arterial oxygen tension difference resulting from almost all forms of general anesthesia is unknown. We hypothesized that inhalation anesthesia influences the intrapulmonary distribution of ventilation (V) and perfusion (Q), leading to less advantageous V/Q matching. Ten healthy volunteers were studied in supine position on ...
Francis Roland C E - - 2010
The authors aimed to test the hypothesis that xenon anesthesia limits adverse hypotensive effects of losartan during acute hemorrhage. In six conscious unsedated Beagle dogs, the systemic and pulmonary circulation were monitored invasively, and two subsequent 60-min hypotensive challenges were performed by (a) induction (propofol) and maintenance of anesthesia with ...
Clemens K E - - 2010
Maternal hypotension is the most frequent complication in spinal anesthesia for Cesarean delivery. Malperfusion of the foetus and nausea and vomiting of the mother are hallmarks of maternal hypotension. In this retrospective data analysis and anesthesia protocols we have investigated to explore the effects of therapeutic interventions for hypotension with ...
Swarts J Douglas JD Department of Otolaryngology, Children's Hospital of Pittsburgh, University of Pittsburgh, PA, USA. - - 2010
The middle ear (ME) surface area/volume ratio (SA/V) is greater than that of the tympanum. The rate of ME pressure decrease is proportional to the ME SA/V. The mastoid air-cell system (MACS) will not function as an ME gas reserve unless the blood perfusion/surface area is much greater for the ...
Enekvist B - - 2010
The rate of uptake of volatile anesthetics is dependent on alveolar concentration and ventilation, blood solubility and cardiac output. We wanted to determine whether increased tidal volume (V(T)), with unchanged end-tidal carbon dioxide partial pressure (P(ET)CO(2)), could affect the arterial concentration of sevoflurane. Prospective, randomized, clinical study. ASA physical status ...
Kim Hyung Tae - - 2010
Monitoring of anesthetic depth is important for successful general anesthesia. It is well known that entropy or BIS monitoring assisted titration of anesthetic drugs decreases their consumption. This study evaluated the effect of remifentanil on consumption of sevoflurane during entropy monitored general anesthesia. Patients were randomly assigned to two groups. ...
Buehner Eva - - 2011
To determine the conditions under which anesthetized pigs can be used in acute noninvasive investigations of ocular hydro- and hemodynamics, the intraocular pressure (IOP) of adult pigs was recorded under the following conditions: (1) after intravenous injection of propofol plus ketamine; (2) during inhalation of isoflurane, and (3) 2 h ...
Baumgartner Christine - - 2010
The direct effects of ketamine-xylazine (KET-XYL) on vascular function have not been investigated in rabbits. The short-term cardiovascular effects of intravenous (IV) KET-XYL bolus injection, therefore, should be investigated using vascular ultrasonography.In this prospective experimental study, KET-XYL anesthesia was induced IV in 9 female New Zealand White rabbits before 3 ...
Brosnan Robert J - - 2011
Digital perfusion pressure (DPP) equals mean arterial pressure (MAP) at the hoof coronet minus digital interstitial pressure (DIP) within the hoof. To test whether lamellar blood flow (LBF) changes proportionately to DPP, anesthesia was induced and maintained with isoflurane in six horses to target a MAP of 60 mmHg. Arterial, ...
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