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Auler José Otavio Costa JO - - 2010
Spinal anesthesia for cesarean delivery may cause severe maternal hypotension and a decrease in cardiac output. Compared to assessment of cardiac output via a pulmonary artery catheter, the FloTrac/Vigileo system may offer a less invasive technique. The aim of this study was to evaluate cardiac output and other hemodynamic measurements ...
Otsuki Denise A - - 2010
Original sevoflurane (Sevo A) is made with water, while a generic sevoflurane (Sevocris) is produced with propylene glycol as a stabilizing additive. We investigated whether the original and generic sevoflurane preparations differed in terms of their minimum alveolar concentration (MAC) values and hemodynamic effects. Sixteen pigs weighing 31.6+/-1.8 kg were ...
Schwartz Arthur E - - 2010
Phenylephrine was administered to increase arterial blood pressure in 6 monkeys anesthetized with isoflurane during both normocapnia (arterial partial pressure of CO2 35 to 44 mm Hg) and hypocapnia (arterial partial pressure of CO2 23 to 29 mm Hg). The doses of phenylephrine required to increase mean blood pressure to ...
Bolliger D - - 2010
BACKGROUND: Knowledge on the effects of volatile anaesthetics on left ventricular (LV) diastolic function in humans in vivo is limited. We tested the hypothesis that sevoflurane, desflurane, and isoflurane do not impair LV diastolic function in young healthy humans. METHODS: Sixty otherwise healthy subjects (aged 18-48 yr) undergoing minor procedures ...
Kawaguchi Masahiko - - 2010
Maintenance of systemic and cerebral hemodynamics and quick recovery from anesthesia are required for craniotomy. We conducted a prospective randomized study to investigate the effects of continuous infusion of landiolol on hemodynamic responses to various stimuli, changes in systemic and cerebral hemodynamics during anesthesia, and recovery from anesthesia in patients ...
Shih Andre C - - 2010
To compare the hemodynamic and respiratory effects of an inspiratory impedance threshold device (ITD) in anesthetized normotensive and hypotensive dogs. Prospective randomized study. Ten adult dogs. Dogs were anesthetized with propofol followed by isoflurane. During spontaneous ventilation, tidal volume (.VT), systolic (SAP), mean (MAP) and diastolic arterial blood pressure, central ...
Tsuchiya M - - 2010
BACKGROUND: The pleth variability index (PVI) is a new algorithm used for automatic estimation of respiratory variations in pulse oximeter waveform amplitude, which might predict fluid responsiveness. Because anesthesia-induced hypotension may be partly related to patient volume status, we speculated that pre-anesthesia PVI would be able to identify high-risk patients ...
Dismukes David I - - 2010
OBJECTIVE: To determine the magnitude of the change in colloid oncotic pressure (COP) associated with general anesthesia in dogs undergoing a variety of elective procedures. DESIGN: Cohort study. ANIMALS: 50 client-owned dogs. PROCEDURES: For each dog, preanesthetic and postanesthetic PCV, plasma total solids (TS) concentration, and COP were determined. The ...
Solakovic Nedim - - 2010
INTRODUCTION: Spinal anesthesia presents reversible interruption of nerve transmission within subarachniod space produced by injection of local anesthetic in cerebrospinal fluid. At the same time it comes to the blockade of particular functions of the nerve transmission. At the focus of this work is the blockade of sympathetic fibres which ...
Ardon Alberto Enrique - - 2010
Dr. Rudolph Matas, in addition to being one of the pioneering and most prestigious vascular surgeons of the 19th century, was an influential figure in the development of anesthesiology in the United States (US). His inquisitive nature and determination to understand medicine were tremendous influences in his development of innovative ...
Constantinides C C Laboratory of Physiology and Biomedical Imaging at the University of Cyprus, Nicosia, Cyprus. - - 2010
This study examines the effects of changing oxygen fractional inspiration ratio (FiO(2)), and nitrous oxide (N(2)O) for the improvement of cardiovascular control of mean arterial blood pressure (MAP) and heart rate (HR) in C57BL/6 mice under isoflurane anesthesia (1.5%) for up to 90 minutes post-induction. Heart rate variability (HRV) indices ...
Ueyama Yukie - - 2009
OBJECTIVE-To determine the effects of IV administration of perzinfotel and a perzinfotel-fentanyl combination on the minimum alveolar concentration (MAC) of isoflurane in dogs. ANIMALS-6 healthy sexually intact Beagles (3 males and 3 females). PROCEDURES-All dogs were instrumented with a telemetry device for continuous monitoring of heart rate, arterial blood pressure, ...
Tamilselvan Perumal - - 2009
BACKGROUND: Hypotension after spinal anesthesia for cesarean delivery remains a major clinical problem. Fluid preloading regimens together with vasopressors have been used to reduce its incidence. Previous studies have used noninvasive arterial blood pressure measurement and vasopressor requirements to evaluate the effect of preload. We used a suprasternal Doppler flow ...
Polaner David M - - 2010
BACKGROUND: The use of local anesthetic test doses is standard practice when performing regional anesthesia. When an intravascular test dose is administered during inhaled anesthesia, the heart rate does not increase in about 25% of children; altered T-wave amplitude is a better indicator. No studies have examined the criteria for ...
Lopez Luis A - - 2009
Objective-To determine the quality and speed of recovery from anesthesia with isoflurane, sevoflurane, or desflurane and determine end-tidal inhalant concentration at certain events during recovery in healthy dogs. Animals-11 healthy dogs. Procedures-Anesthesia was induced with propofol (IV), and dogs were assigned by use of a crossover design to receive isoflurane ...
de Leon A - - 2010
BACKGROUND: The lower esophageal sphincter (LES) and the upper esophageal sphincter (UES) play a central role in preventing regurgitation and aspiration. The aim of the present study was to evaluate the UES, LES and barrier pressures (BP) in obese patients before and during anesthesia in different body positions. METHODS: Using ...
Aarnes Turi K - - 2009
OBJECTIVE: To determine the effect of IV administration of crystalloid (lactated Ringer's solution [LRS]) or colloid (hetastarch) fluid on isoflurane-induced hypotension in dogs. ANIMALS: 6 healthy Beagles. PROCEDURES: On 3 occasions, each dog was anesthetized with propofol and isoflurane and instrumented with a thermodilution catheter (pulmonary artery). Following baseline assessments ...
Aarnes Turi K - - 2009
Objective-To determine the effect of IV administration of crystalloid (lactated Ringer's solution [LRS]) or colloid (hetastarch) fluid on isoflurane-induced hypotension in dogs. Animals-6 healthy Beagles. Procedures-On 3 occasions, each dog was anesthetized with propofol and isoflurane and instrumented with a thermodilution catheter (pulmonary artery). Following baseline assessments of hemodynamic variables, ...
Lopez Luis A - - 2009
OBJECTIVE: To determine the quality and speed of recovery from anesthesia with isoflurane, sevoflurane, or desflurane and determine end-tidal inhalant concentration at certain events during recovery in healthy dogs. ANIMALS: 11 healthy dogs. PROCEDURES: Anesthesia was induced with propofol (IV), and dogs were assigned by use of a crossover design ...
Tobias Joseph D - - 2009
The potent inhalational anesthetic agents are used on a daily basis to provide intraoperative anesthesia. Given their beneficial effects on airway tone and reactivity, they also have a role in the treatment of status asthmaticus that is refractory to standard therapy. Although generally not of clinical significance, these agents can ...
Vincent Caitlin J - - 2009
Objective-To characterize the cardiopulmonary effects of dobutamine and norepinephrine infusion in isoflurane-anesthetized healthy alpacas. Animals-8 adult alpacas. Procedures-Initial baseline cardiovascular, respiratory, and metabolic variables were obtained 30 minutes after induction of isoflurane anesthesia in 8 alpacas (3 females and 5 sexually intact males). Four treatments (dobutamine at 4 and 8 ...
Dyer Robert A - - 2009
BACKGROUND: Hemodynamic responses to vasopressors used during spinal anesthesia for elective Cesarean delivery, have not been well described. This study compared the effects of bolus phenylephrine and ephedrine on maternal cardiac output (CO). The hypothesis was that phenylephrine, but not ephedrine, decreases CO when administered in response to hypotension during ...
Vincent Caitlin J - - 2009
OBJECTIVE: To characterize the cardiopulmonary effects of dobutamine and norepinephrine infusion in isoflurane-anesthetized healthy alpacas. ANIMALS: 8 adult alpacas. PROCEDURES: Initial baseline cardiovascular, respiratory, and metabolic variables were obtained 30 minutes after induction of isoflurane anesthesia in 8 alpacas (3 females and 5 sexually intact males). Four treatments (dobutamine at ...
de Vries A - - 2009
Volatile agent-induced hypotension may contribute to anaesthetic-related morbidity and mortality in horses. Dobutamine is commonly used to support arterial blood pressure (ABP) but little is known about its cardiovascular effects under clinical conditions. The aim of this clinical study was to elucidate the relationship between cardiovascular function and dobutamine infusion ...
Siddik-Sayyid Sahar M - - 2009
BACKGROUND: Hypotension after spinal anesthesia for cesarean delivery is common. Previous studies have demonstrated that a crystalloid fluid "coload" (rapid administration of a fluid bolus starting at the time of intrathecal injection) is superior to the conventional crystalloid preload (fluid administered before the intrathecal injection) for preventing hypotension. Colloid preload ...
Scansen Brian A - - 2009
OBJECTIVE: To evaluate the accuracy of a commercial ultrasonographic cardiac output (CO) monitoring system (UCOMS) in anesthetized Beagles as assessed by comparison with thermodilution CO (TDCO). ANIMALS: 8 healthy anesthetized Beagles. PROCEDURES: Simultaneous UCOMS and TDCO measurements of CO were obtained during 4 hemodynamic states: baseline anesthesia (0.5% to 1.5% ...
Choi Seung Ho - - 2009
Activation of the peripheral nerve system by endotracheal intubation is accompanied by an increase in bispectral index (BIS). Esmolol produces a dose-dependent attenuation of the adrenergic response to endotracheal intubation. Desflurane increases sympathetic nerve activity and plasma norepinephrine relative to sevoflurane. The authors hypothesized that esmolol might blunt the BIS ...
Laredo F G - - 2009
After intravenous induction, six beagles were connected to a Komesaroff machine provided with a single in-circuit vaporiser and ventilated mechanically at either nine or 14 breaths/minute while anaesthetised with either isoflurane or sevoflurane. The vaporiser was initially set at position 4/4 (fully open) and the anaesthetic concentrations were measured after ...
Kerr Carolyn L - - 2009
Objective-To evaluate cardiopulmonary effects of anesthetic induction with diazepam and ketamine or xylazine and ketamine, with subsequent maintenance of anesthesia with isoflurane, in foals undergoing abdominal surgery. Animals-17 pony foals. Procedures-Foals underwent laparotomy at 7 to 15 days of age and laparoscopy 7 to 10 days later. Foals were randomly ...
Teoh Wendy H L - - 2009
BACKGROUND: Spinal anesthesia for cesarean delivery may cause severe maternal hypotension, and a decrease in cardiac output (CO) and blood flow to the placenta. Fluid preloading with crystalloid is ineffective due to rapid redistribution. A "coload" given at the time of cerebrospinal fluid identification may be more effective. Our null ...
Bonhomme Vincent - - 2009
Propofol anesthesia may induce metabolic disturbances and sevoflurane anesthesia arterial hypotension. This study compares both techniques regarding acid-base and hemodynamic status during intracranial surgery. Sixty-one patients were randomized into 2 groups according to anesthesia maintenance, a propofol group (n=30), and a sevoflurane group (n=31). The anesthesia protocol including rocuronium and ...
Prabhakar Hemanshu - - 2009
We hypothesized that like bispectral index, entropy may be anesthetic agent specific. We carried out a study to assess the entropy values of different anesthetics at equi-minimal alveolar concentrations (MACs) with air and nitrous oxide as carrier gases. Thirty adult patients undergoing spine surgery were randomized to receive halothane, isoflurane, ...
Mohammadi S S - - 2009
The present study was conducted to evaluate the effect of scalp infiltration with Bupivacaine on hemodynamic responses during early stimulation in craniotomy under general anesthesia. Thirty six patients were prospectively randomized to receive Bupivacaine scalp infiltration (B group) or a saline control (S group) as an adjuvant to general anesthesia ...
Gibson T J - - 2009
AIM: To investigate the electroencephalographic (EEG) and cardiovascular responses of halothane-anaesthetised calves to non-penetrative captive-bolt stunning. METHODS: Ten calves were minimally anaesthetised with halothane, using an established anaesthesia protocol. The EEG, blood pressure and electrocardiogram (ECG) were recorded before and after non-penetrative captive-bolt stunning. Visual inspection and alterations in the ...
Brenck F - - 2009
OBJECTIVE: To determine risk factors for developing hypotension after spinal anesthesia for cesarean section to prevent obstetric patients from hypotensive episodes potentially resulting in intrauterine malperfusion and endangering the child. METHODS: The data from 503 women, having received spinal anesthesia for cesarean sections were investigated using online gathered vital signs ...
Atayde Ingrid Bueno - - 2009
PURPOSE: To evaluate and describe immediate effects of the infusion of saline solution heated by SAF in bitches submitted to halothane anesthesia. METHODS: Thirteen bitches were employed and submitted to elective ovariohysterectomy in acclimatized operating room at 22 degrees C, allocated in two groups: GI, which received non-heated fluid and ...
Carvalho B - - 2009
BACKGROUND: Pre-loading with hetastarch decreases the incidence and severity of hypotension after spinal anesthesia for cesarean delivery. However, pharmacokinetic studies with crystalloid predict that fluid loading should be more efficacious if rapidly administered immediately after induction of spinal anesthesia. The aim of this study was to compare pre- and co-loading ...
Meiser Andreas - - 2009
The anaesthetic conserving device (AnaConDa), Sedana Medical, Sundbyberg, Sweden) facilitates administration of isoflurane or sevoflurane by liquid infusion. An anaesthetic reflector inside the device conserves exhaled anaesthetic and re-supplies it during inspiration. In this bench study, we examined the influence of infusion rates and ventilatory settings on the resulting anaesthetic ...
Egger Christine - - 2009
To determine if the preanesthetic administration of ephedrine would prevent anesthesia-induced hypotension in dogs and cats, 10 cats were anesthetized with acepromazine, butorphanol, ketamine, and isoflurane, and 8 dogs were anesthetized with acepromazine, morphine, propofol, and halothane. Cats received ephedrine or saline 10 minutes after premedication. Dogs received ephedrine or ...
Sakai Kazuyuki - - 2009
General anesthesia causes peripheral vasodilation. We thus hypothesized that patients with increased peripheral vascular tone would become more hypotensive after the induction of general anesthesia compared to those without increased peripheral vascular tone. To test this hypothesis, we compared the decrease in blood pressure after anesthetic induction between patients with ...
Reddy Anilkumar K AK Department of Medicine, Section of Cardiovascular Sciences, Baylor College of Medicine and The Methodist DeBakey Heart & Vascular Center, Houston, TX 77030, USA. - - 2009
Isoflurane is the most commonly used anesthetic in mice. We studied the effect of low and high levels of isoflurane (also a potent coronary vasodilator) on aortic impedance in mice. Aortic impedance was determined using pressure and flow velocity signals at baseline (B, pentobarbital anesthesia), low (Isol, 1%), and high ...
Hashimoto Masakazu - - 2008
To develop an experimental model and evaluate the effects of the magnitude and duration of pressure, the rat abdominal wall (25x20 mm) was subjected to compression either by a weight or by two magnets. In the weight compression tests, a steel plate was inserted under anesthesia into the rat peritoneal ...
Lima-Rodríguez J R - - 2008
OBJECTIVE: To assess cardiac and hemodynamic responses and body temperature during long-term general anesthesia using sevoflurane/fentanyl after premedication with a tiletamine/zolazepam/medetomidine combination in swine undergoing experimental pancreas transplantation. MATERIALS AND METHODS: Twelve Landrace female pigs of means weight 46.4 +/- 5.1 kg were premedicated by intramuscular administration of tiletamine/zolazepam (3.5 ...
Braz Leandro G - - 2008
Some properties of the volatile anesthetics, such as vasodilatation and myocardial depression, combined with the sympathetic inhibition that alpha2-agonists can produce, may determine hemodynamic alterations during aortic surgery. The interaction between dexmedetomidine (DEX), an alpha2-agonist, and sevoflurane during aortic surgery is unknown. We studied the effects of DEX on hemodynamics ...
Hanley Christopher S - - 2008
Free-ranging Hoffmann's two-toed sloths (Choloepus hoffmanni; n=26) and brown-throated three-toed sloths (Bradypus variegatus; n=15) were manually captured and immobilized with 2.5 mg/kg ketamine + 0.02 mg/kg medetomidine administered intramuscularly. Physical examinations were conducted on each sloth 10 min after initial injection, and blood, fecal, and ectoparasite samples were collected. Heart ...
Madi-Jebara Samia - - 2008
GOALS: The aim of this study is to compare the efficacy of HES 130/0.4, a new hydroxyethyl starch, to lactated Ringer's solution (LR) in the prevention of hypotension after spinal anesthesia for cesarean section (CS). MATERIAL AND METHODS: One hundred and twenty nonlaboring ASA I and II women having non ...
Martin-Jurado Olga - - 2008
OBJECTIVE: To determine the effect of inhalation of isoflurane at end-tidal concentrations greater than, equal to, and less than the minimum anesthetic concentration (MAC) on bispectral index (BIS) in chickens. Animals-10 chickens. PROCEDURES: For each chicken, the individual MAC of isoflurane was determined by use of the toe-pinch method. After ...
Goldmann Anton - - 2008
BACKGROUND: Combination of epidural and general anesthesia (combined anesthesia) avoids the intraoperative use of intravenous analgesics and may reduce the surgical stress response during major abdominal surgery. This study examines the differences in intraoperative hemodynamic stability, cortisol levels and activity of cardiovascular hormones between combined anesthesia and isoflurane/fentanyl anesthesia. MATERIAL/METHODS: ...
Taivainen T - - 2008
BACKGROUND AND OBJECTIVE: The reliability of the Bispectral Index for evaluating and monitoring the depth of general anaesthesia in children is not as great as for that in adults. Therefore we analysed Bispectral Index performance in children by comparing changes in Bispectral Index values during a standardized and equipotent anaesthetic ...
Owczuk Radoslaw - - 2008
BACKGROUND AND OBJECTIVES: Side effects of spinal anesthesia include arterial hypotension and bradycardia. Both of them may be induced by sympathetic nerve blockade as well as by the Bezold-Jarisch reflex, which may be mediated by peripheral serotonin receptors (5-HT(3) type). The aim of this study was to verify the hypothesis ...
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