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Taghavi Sharven S From the Department of Surgery (S.T., S.N.J., L.M.F., R.E.M., J.D., L.O.S., A.P., J.F.R., T.A.S., A.J.G.), Biostatistics Consulting Center (J.P.G.), and Cardiovascular Research Center (S.T., S.R.H.), School of Medicine (H.V., C.M.), Temple University, Philadelphia, - - 2014
Many penetrating trauma patients in severe hemorrhagic shock receive positive pressure ventilation (PPV) upon transport to definitive care, either by intubation (INT) or bag-valve mask (BVM). Using a swine hemorrhagic shock model that simulates penetrating trauma, we proposed that severely injured patients may have better outcomes with "permissive hypoventilation," where ...
Cathcart Curtis C CC *Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA; †Department of Upper Extremity and Micro Surgery, Athens Orthopedic Clinic, Athens GA; and ‡Landstuhl Regional Medical Center, Landstuhl, - - 2014
To correlate near-infrared spectroscopy (NIRS) and the tibial intracompartmental perfusion pressure (TIPP) in an acute limb compartmental syndrome. Landrace swine were subdivided into 2 groups: plasma infusion (n = 16) and blunt trauma plus plasma infusion (n = 15). NIRS sensors were placed over the craniolateral muscle compartment of proximal ...
Johnson Jillian A JA Department of Psychology, University of Calgary, 2500 University Dr NW, Calgary, Alberta, T2N 1N4, - - 2014
Blunted blood pressure (BP) dipping during nighttime sleep has been associated with an increased risk of cardiovascular events. Psychological traits have been associated with prolonged cardiovascular activation and a lack of cardiovascular recovery. This activation may extend into nighttime sleep and reduce BP dipping. This study aims to evaluate the ...
Das Satarupa S Department of Physiology, Medical College of Wisconsin, Milwaukee, - - 2014
Administration of exogenous L-Arginine (L-Arg) attenuates Angiotensin II (AngII)-mediated hypertension and kidney disease in rats. The present study assessed renal hemodynamics and pressure-diuresis-natriuresis in anesthetized rats infused with vehicle, AngII (20 ng/kg/min, iv) or AngII + L-Arg (300 μg/kg/min, iv). Increasing renal perfusion pressure (RPP) from approximately 100 to 140 ...
Shearin Amanda E AE Department of Pharmacy Practice and Science, College of Pharmacy, University of Arizona, Tucson, Arizona (Drs Shearin, Patanwala, and Erstad); and Department of Surgery, College of Medicine, University of Arizona, Tucson, Arizona (Dr - - 2014
Propofol use may lead to hypotension in trauma patients intubated in the emergency department. In this study, predictors of hypotension were identified. We hypothesized that demographic variables could be associated with hypotension. Hypotension occurred in 33 of 200 patients. In the multivariate analysis, hypotension was associated with patient age greater ...
Andrews Penny L - - 2013
Adult respiratory distress syndrome is often refractory to treatment and develops after entering the health care system. This suggests an opportunity to prevent this syndrome before it develops. The objective of this study was to demonstrate that early application of airway pressure release ventilation in high-risk trauma patients reduces hospital ...
Saliba Lina - - 2013
Although chronic hypertension is associated with long-term complications, few studies directly examine the effects of in-hospital acute hypertensive episodes in trauma patients. The aim was to determine whether there is an association between in-hospital acute hypertension and morbidity. We included trauma patients between 45 and 89 years who presented to a ...
Harih Gregor - - 2013
Huge areas of work are still done manually and require the usages of different powered and non-powered hand tools. In order to increase the user performance, satisfaction, and lower the risk of acute and cumulative trauma disorders, several researchers have investigated the sizes and shapes of tool-handles. However, only a ...
Kretschmer Jorn - - 2013
The application of mechanical ventilation is a life-saving routine therapy that allows the patient to overcome the physiological impact of surgeries, trauma or critical illness by ensuring vital oxygenation and carbon dioxide removal. Above a certain level of minute ventilation (usually set to ensure acceptable carbon dioxide removal and oxygenation) ...
Qi Zhenbin - - 2013
A fiber pressure sensor with a collimator at the off-center position of a diaphragm is demonstrated. The detection mechanism is incident-angle sensitive rather than traditional working-distance sensitive. Due to the small beam divergence of the collimator, the control on working distance is less stringent, and high sensitivity can be realized ...
Bernon Jessica K - - 2013
Objectives. The primary aim was to assess the need for objective cuff pressure monitoring in the theatre complex and trauma centre at Groote Schuur Hospital, Cape Town, South Africa. Secondary aims were to determine whether the tube size, tube make or place of intubation affected cuff pressure.Method. Endotracheal tube cuff ...
Paulus Eric J - - 2013
Hyperarousal is a hallmark of posttraumatic stress disorder (PTSD). PTSD has been associated with increased blood pressure (BP) and heart rate (HR) in veteran populations. We retrospectively identified male patients consulted to outpatient psychiatry at the Iowa City Veterans Affairs Healthcare System. Patients were divided into PTSD (n = 88) ...
Norman Greg J - - 2013
Over a million children are subjected to some form trauma in the United States every year. Early trauma has been shown to have deleterious effects on cardiovascular health in adulthood. However, the presence of strong social relationships as an adult can buffer an individual against many of the harmful effects ...
Jayaram Archana - - 2012
BACKGROUND. : Positive pressure ventilation (PPV) is provided by manual ventilation devices such as self-inflating bags (SIB), flow inflating bags and T-piece resuscitators. The objective of this study is to compare the effect of type of manual ventilation device on overall response to resuscitation among preterm neonates born < 35 ...
Picetti Edoardo - - 2012
INTRODUCTION: Discrepant data exist regarding the incidence and severity of clinical problems related to intra-hospital transport of brain-injured patients and no consensus exists whether modern-day intra-hospital transport represents a safe or potentially problematic environment for neurointensive care unit (NICU) patients. METHODS: We examined the incidence of clinical complications and physiological ...
Hildebrand F - - 2012
ABSTRACT: Despite the high incidence and prognostic relevance of hemorrhagic shock, abdominal and blunt chest trauma in multiply injured patients, there are no animal models combining these injuries. Therefore, we established a new porcine multiple trauma model consisting of blunt chest trauma, penetrating abdominal trauma (two incisions in the right ...
Xia Xie - - 2012
Objective To explore the efficacy of homemade hemostatics of injected gelatin matrix (HIGM) for immediately treating blunt hepatic trauma in canine model without additional pressure. Methods A total of 27 commercial hybrid dogs underwent celiotomy to establish hepatic trauma model after general anesthesia. The dogs were prospectively randomized into 3 ...
Convertino Victor A - - 2012
The respiratory pump can be optimized to enhance circulation in patients with hypotension by having patients spontaneously breathe through a low level of inspiratory resistance. This can be achieved with an impedance threshold device (ITD) designed to provide 7 cm H2O resistance during spontaneous inspiration with minimal resistance during expiration. ...
Maung Adrian A - - 2012
Airway pressure release ventilation (APRV) is used both as a rescue therapy for patients with acute lung injury and as a primary mode of ventilation. Unlike assist-control volume (ACV) ventilation that uses spontaneous breathing trials, APRV weaning consists of gradual decreases in supporting pressure. We hypothesized that the APRV weaning ...
Kelly Y P - - 2012
New-onset arterial hypertension is a well-recognised complication of kidney trauma. Cases have been described in young healthy athletes with hypertension arising years after sports-related trauma. The pathophysiology of this disease is thought to arise from intrarenal arterial stenosis resulting from rapid deceleration during the initial injury. This leads to arterial ...
Arts Johanna W M - - 2012
Transportation of laboratory rodents unavoidably causes stress. Nevertheless, very little is known about the effects of transportation and how long it takes for the animal to recuperate. In the present study, we investigated physiological and behavioral parameters before and after transportation in both transported and nontransported animals. We took blood ...
Christofaro D G D - - 2011
The purpose of this study was to assess the relationship between blood pressure (BP) levels and physical activity (PA) domains accounting for overweight/obesity. Adolescents aged 10 to 17 years old were recruited (n = 1021). International Obesity Task Force (IOTF) criteria were used to define overweight and obesity. High BP was defined ...
Glorioso Nicola - - 2011
Essential hypertension is highly prevalent in the elderly population, exceeding 70% in people older than 60 yr of age, and remains a leading risk factor for heart disease, stroke, and chronic renal disease. Elucidation of genetic determinants is critical but remains a challenge due to its complex, multifactorial pathogenesis. We ...
Hersch Anat - - 2011
Exposure of myocardium to a mechanical impact may produce premature ventricular contractions (PVCs). High-intensity focused ultrasound was reported to generate PVCs, while microbubbles at the target increased absorption, thus, promoting energy localization and decreased PVC threshold. The objective was to investigate the benefit of a two-stage ultrasonic transmission: (1) asymmetric ...
Regli Adrian - - 2011
Femoral venous access is frequently used in critically ill patients. Because raised intra-abdominal pressure (IAP) is also frequently found in this group of patients, we examined the impact of IAP and positive end-expiratory pressure (PEEP) on femoral venous pressure (FVP) and femoral venous oxygen saturation (Sfvo2) in an animal model. ...
Zhao Yi - - 2011
The growth and enlargement of jaw cysts are associated with raised intracystic pressure and bone resorption surrounding the cysts. The major bone-resorbing cells are the osteoclasts. They are acting under the influence of local bone-resorbing factors: prostaglandins, proteinases and cytokines. It was found that positive pressure enhanced the expression of ...
Hsieh Paul A - - 2011
When the Macondo well was shut in on July 15, 2010, the shut-in pressure recovered to a level that indicated the possibility of oil leakage out of the well casing into the surrounding formation. Such a leak could initiate a hydraulic fracture that might eventually breach the seafloor, resulting in ...
Boyd John H - - 2011
To determine whether central venous pressure and fluid balance after resuscitation for septic shock are associated with mortality. We conducted a retrospective review of the use of intravenous fluids during the first 4 days of care. Multicenter randomized controlled trial. The Vasopressin in Septic Shock Trial (VASST) study enrolled 778 ...
Stergiou G S - - 2011
Oscillometric devices are being widely used for ambulatory, home and office blood pressure (BP) measurement, and several of them have been validated using established protocols. This cross-sectional study assessed the impact on antihypertensive treatment decisions of replacing the mercury sphygmomanometer by a validated oscillometric device. Consecutive subjects attending a hypertension ...
Sweeney Daniel A - - 2010
High mortality in the 2001 US and recent European anthrax outbreaks suggests that better understanding of the effects of the toxins produced by this bacterium is needed to improve treatment. Here, 24-h edema (ETx) and lethal (LeTx) toxin infusions were investigated for 96 hin sedated canines receiving mechanical ventilation. The ...
Shanmugarajah P D - - 2010
A 42-year-old woman with a body mass index of 36 presented with visual obscurations and headaches. She had a visual acuity of 6/5 bilaterally, a constricted right visual field and bilateral papilloedema. Idiopathic intracranial hypertension (IIH) was suspected but brain magnetic resonance imaging and venography demonstrated multiple enhancing lesions in ...
Recek C - - 2010
Pressure differences play an important role in the hemodynamics of both arterial and venous circulation. Venous ambulatory pressure gradient of about 35 mm Hg arises during the activity of the calf muscle venous pump between the veins in the thigh and the lower leg; this is the initiator launching venous ...
Pasion Editha - - 2010
To determine if the monitor cursor-line feature on bedside monitors is accurate for measuring central venous and pulmonary artery pressures in cardiac surgery patients. Central venous and pulmonary artery pressures were measured via 3 methods (end-expiratory graphic recording, monitor cursor-line display, and monitor digital display) in a convenience sample of ...
Alsaigh Tom - - 2011
Venous hypertension is associated with microvascular inflammation, restructuring, and apoptosis, but the cellular and molecular mechanisms underlying these events remain uncertain. In the present study, we tested the hypothesis that elevated venous pressure and reduction of shear stress induce elevated enzymatic activity. This activity in turn may affect endothelial surface ...
Mosti G - - 2010
Hemodynamic effects of compression devices in patients with venous insufficiency are still under dispute. The aim of this paper was to describe a method which is able to give quantitative results concerning an improvement of the venous pumping function by using compression devices in patients with venous insufficiency. The ejection ...
Mosti G - - 2010
The aim of this study was to demonstrate the usefulness of Duplex in measuring venous reflux and changes in reflux caused by leg compression. Twelve patients with severe incompetence of the great saphenous vein (GSV) were investigated. A special Duplex probe was fixed by tapes on the mid-thigh portion of ...
Sielatycki John A - - 2011
Limb venous compliance decreases with advancing age, even in healthy humans. To test the hypothesis that adrenergic mechanisms contribute to age-associated reductions in limb venous compliance, we measured calf venous compliance before and during acute systemic α- and β-adrenergic blockade in eight young (27 ± 1 yr old, mean ± ...
Kissoon N - - 2010
We compared saturations from a paediatric central venous oximetry catheter with co-oximetry values with changes in drug infusions, intravascular blood volume and hypoxia in an animal model. Piglets (large white) were anaesthetised, intubated and mechanically ventilated. PediaSat oximetry catheters were placed in the superior vena cava via jugular vein cut-down ...
Deol Gur Raj - - 2011
Bedside ultrasound examination could be used to assess jugular venous pressure (JVP), and thus central venous pressure (CVP), more reliably than clinical examination. The study was a prospective, blinded evaluation comparing physical examination of external jugular venous pressure (JVPEXT), internal jugular venous pressure (JVPINT), and ultrasound collapse pressure (UCP) with ...
Kawano Hiroshi - - 2010
Greater venous compliance is associated with attenuation of the tolerance response to orthostatic stress and reduced incidence of venous diseases. Resistance training induces tolerance to orthostatic challenge and the growth of capillaries, which may lead to negative and positive effects on venous compliance, respectively. It has not been confirmed, however, ...
Learn Christopher P - - 2010
Tissue Doppler imaging (TDI) measurements have been demonstrated to correlate with central venous pressure (CVP) in adults. We hypothesize that TDI measurements also correlate with CVP in children after cardiac surgery. Patients younger than 10 years with invasive CVP monitoring after cardiac surgery were studied. Annular tissue and atrioventricular inflow ...
Larsson Magnus - - 2010
Venoarterial ECMO has been utilized in trauma patients to improve oxygenation, particularly in the setting of pulmonary contusions and ARDS. We hypothesized that venoarterial ECMO could reduce the central venous pressure in the trauma scenario, thus, alleviating major venous hemorrhage. Ten swine were cannulated for venoarterial ECMO. Central venous pressure, ...
Jansen Jos R C - - 2010
PURPOSE OF REVIEW: The physiology of the venous part of the human circulation seems to be a forgotten component of the circulation in critical care medicine. One of the main reasons, probably, is that measures of right atrial pressure (Pra) do not seem to be directly linked to blood flow. ...
Dias N V - - 2010
AIM: To study hemodynamic and blood oxygenation changes in patients undergoing carotid endarterectomy (CEA) under general (GA) or locoregional (LRA) anesthesia. METHODS: Prospective non-randomized study including 50 patients undergoing CEA (31 men, mean age 72 (range 50-84) years-old under GA (N.=23) or LRA (N.=27). Systemic blood pressure, ECG, venous oxygen ...
Mosti G - - 2010
A too high resting pressure of compression devices is poorly tolerated and may cause skin defects, especially in patients with concomitant arterial occlusive disease. To investigate whether low compression pressure will improve venous pumping function in patients with venous incompetence. Venous pumping function was assessed in 20 patients with severe ...
Myers Cynthia D - - 2010
After univentricular Fontan conversion, systemic venous pressure serves as the sole driving force for transpulmonary blood flow. Consequently, systemic venous return is markedly altered and ventricular filling is subnormal. The mechanisms and time course of systemic adaptation to Fontan conversion are incompletely understood. We hypothesized that acute elevation in systemic ...
Wong Heong-Ieng - - 2010
Nutcracker syndrome occurs when the left renal vein (LRV) is compressed between the superior mesenteric artery and the aorta, and this syndrome is often characterized by venous hypertension and related pathologies. However, invasive studies such as phlebography and measuring the reno-caval pressure gradient should be performed to identify venous hypertension. ...
Polaschegg Hans-Dietrich - - 2010
The historical development of the use of pressure sensors as protective system against blood loss to the environment is reviewed. In spite of early warnings about the deficiency of such sensors, the venous pressure sensor is still formally accepted as protective system against blood loss to the environment in case ...
Di Nardo M - - 2010
Although significant steps have been taken to monitor complex hemodynamics in neonatal and pediatric intensive care units, cardiovascular function in neonates is still evaluated by measuring blood pressure, heart rate, diuresis, central venous pressure (if a central venous catheter was placed), capillary refill time and oxygen saturation measurement in the ...
Wuethrich Patrick Yves - - 2010
The case of a 38-year old man with recurrent adenocarcinoma of the right lung and infiltration of the thoracic wall, who underwent a right pneumonectomy with thoracic wall resection, is described. Dissection of the right pulmonary hilous was extremely difficult due to the previous operations. The superior vena cava (SVC) ...
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