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Alsaigh Tom T Department of Bioengineering, The Institute for Engineering in Medicine, University of California San Diego, La Jolla, CA 92093-0412, - - 2011
Venous hypertension is associated with microvascular inflammation, restructuring, and apoptosis, but the cellular and molecular mechanisms underlying these events remain uncertain. In the present study, we tested the hypothesis that elevated venous pressure and reduction of shear stress induce elevated enzymatic activity. This activity in turn may affect endothelial surface ...
Mosti G - - 2010
Hemodynamic effects of compression devices in patients with venous insufficiency are still under dispute. The aim of this paper was to describe a method which is able to give quantitative results concerning an improvement of the venous pumping function by using compression devices in patients with venous insufficiency. The ejection ...
Mosti G - - 2010
The aim of this study was to demonstrate the usefulness of Duplex in measuring venous reflux and changes in reflux caused by leg compression. Twelve patients with severe incompetence of the great saphenous vein (GSV) were investigated. A special Duplex probe was fixed by tapes on the mid-thigh portion of ...
Sielatycki John A - - 2011
Limb venous compliance decreases with advancing age, even in healthy humans. To test the hypothesis that adrenergic mechanisms contribute to age-associated reductions in limb venous compliance, we measured calf venous compliance before and during acute systemic α- and β-adrenergic blockade in eight young (27 ± 1 yr old, mean ± ...
Kissoon N - - 2010
We compared saturations from a paediatric central venous oximetry catheter with co-oximetry values with changes in drug infusions, intravascular blood volume and hypoxia in an animal model. Piglets (large white) were anaesthetised, intubated and mechanically ventilated. PediaSat oximetry catheters were placed in the superior vena cava via jugular vein cut-down ...
Deol Gur Raj - - 2011
Bedside ultrasound examination could be used to assess jugular venous pressure (JVP), and thus central venous pressure (CVP), more reliably than clinical examination. The study was a prospective, blinded evaluation comparing physical examination of external jugular venous pressure (JVPEXT), internal jugular venous pressure (JVPINT), and ultrasound collapse pressure (UCP) with ...
Kawano Hiroshi - - 2010
Greater venous compliance is associated with attenuation of the tolerance response to orthostatic stress and reduced incidence of venous diseases. Resistance training induces tolerance to orthostatic challenge and the growth of capillaries, which may lead to negative and positive effects on venous compliance, respectively. It has not been confirmed, however, ...
Learn Christopher P - - 2010
Tissue Doppler imaging (TDI) measurements have been demonstrated to correlate with central venous pressure (CVP) in adults. We hypothesize that TDI measurements also correlate with CVP in children after cardiac surgery. Patients younger than 10 years with invasive CVP monitoring after cardiac surgery were studied. Annular tissue and atrioventricular inflow ...
Larsson Magnus - - 2010
Venoarterial ECMO has been utilized in trauma patients to improve oxygenation, particularly in the setting of pulmonary contusions and ARDS. We hypothesized that venoarterial ECMO could reduce the central venous pressure in the trauma scenario, thus, alleviating major venous hemorrhage. Ten swine were cannulated for venoarterial ECMO. Central venous pressure, ...
Jansen Jos R C - - 2010
PURPOSE OF REVIEW: The physiology of the venous part of the human circulation seems to be a forgotten component of the circulation in critical care medicine. One of the main reasons, probably, is that measures of right atrial pressure (Pra) do not seem to be directly linked to blood flow. ...
Dias N V - - 2010
AIM: To study hemodynamic and blood oxygenation changes in patients undergoing carotid endarterectomy (CEA) under general (GA) or locoregional (LRA) anesthesia. METHODS: Prospective non-randomized study including 50 patients undergoing CEA (31 men, mean age 72 (range 50-84) years-old under GA (N.=23) or LRA (N.=27). Systemic blood pressure, ECG, venous oxygen ...
Mosti G - - 2010
A too high resting pressure of compression devices is poorly tolerated and may cause skin defects, especially in patients with concomitant arterial occlusive disease. To investigate whether low compression pressure will improve venous pumping function in patients with venous incompetence. Venous pumping function was assessed in 20 patients with severe ...
Myers Cynthia D - - 2010
After univentricular Fontan conversion, systemic venous pressure serves as the sole driving force for transpulmonary blood flow. Consequently, systemic venous return is markedly altered and ventricular filling is subnormal. The mechanisms and time course of systemic adaptation to Fontan conversion are incompletely understood. We hypothesized that acute elevation in systemic ...
Wong Heong-Ieng - - 2010
Nutcracker syndrome occurs when the left renal vein (LRV) is compressed between the superior mesenteric artery and the aorta, and this syndrome is often characterized by venous hypertension and related pathologies. However, invasive studies such as phlebography and measuring the reno-caval pressure gradient should be performed to identify venous hypertension. ...
Polaschegg Hans-Dietrich - - 2010
The historical development of the use of pressure sensors as protective system against blood loss to the environment is reviewed. In spite of early warnings about the deficiency of such sensors, the venous pressure sensor is still formally accepted as protective system against blood loss to the environment in case ...
Di Nardo M - - 2010
Although significant steps have been taken to monitor complex hemodynamics in neonatal and pediatric intensive care units, cardiovascular function in neonates is still evaluated by measuring blood pressure, heart rate, diuresis, central venous pressure (if a central venous catheter was placed), capillary refill time and oxygen saturation measurement in the ...
Wuethrich Patrick Yves - - 2010
The case of a 38-year old man with recurrent adenocarcinoma of the right lung and infiltration of the thoracic wall, who underwent a right pneumonectomy with thoracic wall resection, is described. Dissection of the right pulmonary hilous was extremely difficult due to the previous operations. The superior vena cava (SVC) ...
Chao Chia Sheng - - 2010
Iatrogenic injury is a difficult situation for a surgeon. Being successful in saving a patient at risk is the major concern in this situation. Once an iatrogenic injury to the superior vena cava (SVC) is found, increasing the intrathoracic pressure is theoretically able to overcome the venous pressure and to ...
Lakhal Karim - - 2010
PURPOSE: Passive leg raising (PLR) is a maneuver performed to test the cardiac Frank-Starling mechanism. We assessed the influence of PLR-induced changes in preload on the performance of PLR-induced change in pulse pressure (Delta(PLR)PP) and cardiac output (Delta(PLR)CO) for fluid responsiveness prediction. METHODS: Sedated, nonarrhythmic patients with persistent shock were ...
Martinez Ricky R Department of Mechanical Engineering, The University of Texas at San Antonio, San Antonio, TX 78249, - - 2010
Venous tortuosity is associated with multiple disease states and is often thought to be a consequence of venous hypertension and chronic venous disease. However, the underlying mechanisms of vein tortuosity are unclear. We hypothesized that increased pressure causes vein buckling that leads to a tortuous appearance. The specific aim of ...
Chung Chih-Ping - - 2010
It has been demonstrated that internal jugular vein (IJV) compression aggravates headache intensity in patients of migraine. We hypothesized that patients with migraine may have veins that are less distensible; consequently, these veins are more likely to develop and transmit venous hypertension caused by the increased venous blood volume during ...
Latham Heath E - - 2010
Early goal directed therapy improves survival in patients with septic shock. Central venous pressure (CVP) monitoring is essential to guide adequate resuscitation. Use of peripherally inserted central catheters (PICC) is increasing, but little data exists comparing a PICC to a conventional CVP catheter. We studied the accuracy of a novel ...
Calotă F - - 2010
The valvular segment is a distinct venous structure, which, from a morphological point of view, is comprised of the following components: the valvular insertion, the valvular gorge entrance orifice, the valvular defile, the valvular gorge exit orifice, the valvular sinus. Endoscopic and echo Doppler examinations are used to identify the ...
Smit Jeroen M - - 2010
During deep inferior epigastric artery perforator (DIEP) flap dissection, we noted that in many cases the superficial vein on the ipsilateral side of the flap was engorged and tense, and in others, it was empty. This led us to believe that the pressure is increased as the result of preferential ...
Amirak Emre E Section of Molecular Medicine, National Heart and Lung Institute, Imperial College London, Sir Alexander Fleming Building, South Kensington Campus, London SW7 2AZ, - - 2010
Vascular smooth muscle cell (VSMC) proliferation remains a major cause of veno-arterial graft failure. We hypothesised that exposure of venous SMCs to arterial pressure would increase KLF5 expression and that of cell cycle genes. Porcine jugular veins were perfused at arterial or venous pressure in the absence of growth factors. ...
Wardhan Richa - - 2009
PURPOSE OF REVIEW: The focus of intraoperative monitoring is moving away from invasive monitoring. This has been attributed to procedure time, cost, and the known risks, which include carotid artery puncture, arrhythmia, pneumothorax, and infection. Until recently, the venous system's contribution to the circulatory system has been incorrectly identified as ...
Krishnan Usha S US Department of Pediatric Cardiology, New York Medical College, Valhalla, NY 10595, USA. - - 2009
The Fontan circulation is critically dependent on elevated venous pressures to sustain effective venous return. We hypothesized that chronically increased systemic venous pressures lead to adaptive changes in regional and peripheral vessels to maintain cardiac output, especially when patients are upright. Nine post-Fontan procedure patients (aged 13 to 24 years) ...
Grissom Colin K - - 2009
OBJECTIVE: To correlate physical examination findings, central venous pressure, fluid output, and central venous oxygen saturation with pulmonary artery catheter parameters. DESIGN: Retrospective study. SETTING: Data from the multicenter Fluid and Catheter Treatment Trial of the National Institutes of Health Acute Respiratory Distress Syndrome Network. PATIENTS: Five hundred thirteen patients ...
Mitchell Matthew D - - 2009
This paper is a report of a review to assess clinical studies comparing the effectiveness of different means of maintaining central venous catheter patency. Flushing with heparin is a routine part of central venous catheter maintenance, but it presents risks, including heparin-induced thrombocytopenia. Other techniques used to prevent occlusion of ...
Trzebicki J - - 2009
To ensure appropriate function of the transplanted organ, it is necessary to adequately maintain vascular volume during the kidney transplantation procedure. For this purpose, central venous pressure (CVP) is monitored through a catheter inserted into the superior vena cava (SVC). Central venous cannulation is associated with a risk of serious ...
Macha Douglas B - - 2009
PURPOSE: To evaluate a widely used nontunneled triple-lumen central venous catheter in order to determine whether the largest of the three lumina (16 gauge) can tolerate high flow rates, such as those required for computed tomographic angiography. MATERIALS AND METHODS: Forty-two catheters were tested in vitro, including 10 new and ...
Hsieh Teng-Kuei - - 2009
We describe a case of the sudden onset of cardiovascular collapse during emergence from anesthesia resulting from a massive venous air embolism, which was detected by transesophageal echocardiography. We present this case to remind anesthesiologists to be aware of the risk of a sudden return of air trapped in the ...
Grissom Colin K - - 2009
OBJECTIVE:: To correlate physical examination findings, central venous pressure (central venous pressure), fluid output, and central venous oxygen saturation with pulmonary artery catheter parameters. DESIGN:: Retrospective study. SETTING:: Data from the multicenter Fluid and Catheter Treatment Trial of the National Institutes of Health Acute Respiratory Distress Syndrome Network (National Institutes ...
Thalhammer Christoph - - 2009
AIM OF THE STUDY: Information on central venous pressure (CVP) is helpful in clinical situations like cardiac failure and sepsis. Compression ultrasound (CU) of a forearm vein has been shown to be a reliable method for CVP measurement when assessed by experienced personal under study conditions. To test the hypothesis, ...
Kulkarni Venugopal - - 2009
Patients undergoing bi-directional Glenn shunt for various congenital anomalies of the heart will have their superior vena cava (SVC) clamped during the procedure. The duration of the procedure is variable, ranging from five to 30 minutes. This can affect the cerebral perfusion due to raised venous pressure [Cerebral blood flow ...
Keller A Scott - - 2009
BACKGROUND: Early goal-directed therapy for severe sepsis or septic shock improves outcomes but requires placement of a central venous catheter to measure central venous pressure (CVP), which may delay timely resuscitation and cause catheter-related complications. In addition, nonintensivists may not start early aggressive fluid resuscitation because of difficulty estimating CVP ...
Nagdev Arun D - - 2010
STUDY OBJECTIVE: Among adult emergency department (ED) patients undergoing central venous catheterization, we determine whether a greater than or equal to 50% decrease in inferior vena cava diameter is associated with a central venous pressure of less than 8 mm Hg. METHODS: Adult patients undergoing central venous catheterization were enrolled ...
Patel Tanmay R - - 2009
OBJECTIVE: Hirayama disease is a nonprogressive cervical myelopathy associated with epidural venous engorgement and spinal canal narrowing. It has been unclear whether dural venous pressure influences spinal cord injury in this illness. CLINICAL PRESENTATION: An 18-year-old man presented with profound hand weakness and atrophy that had developed over a period ...
Cohen Paul G - - 2009
Prostatic enlargement occurs over the course of a lifetime and is associated with many risk factors. Recent observations demonstrate that valvular damage, occurring in the internal spermatic veins results in increased hydrostatic pressures that lead to venous backflow. Two consequences of venous backflow are the prolonged exposure to hydrostatic pressure ...
Palardy Maryse M Brigham and Women's Hospital, Boston, Mass; Duke Medical Center, Durham, NC, - - 2009
Dynamic mitral regurgitation (MR) contributes to decompensation in chronic dilated heart failure. Reduction of MR was the primary physiological end point in the ESCAPE trial, which compared acute therapy guided by jugular venous pressure, edema, and weight (CLIN) with therapy guided additionally by pulmonary artery catheters (PAC) toward pulmonary wedge ...
Wittels Bernard - - 2009
A 25-yr-old obese parturient with mild asthma underwent an uneventful spinal anesthetic for primary cesarean delivery. Within 4 h after delivery, the patient twice developed acute shortness of breath, inspiratory stridor, and hypoxemia that required intubation. A battery of blood tests revealed no evidence of an allergic reaction. She had ...
Krabbendam Ineke - - 2009
OBJECTIVE: Formerly preeclamptic women with low plasma volume are at increased risk of recurrent gestational hypertensive disease. We hypothesized that a 4-week cycling training in formerly preeclamptic women improves (venous) hemodynamic function. METHODS: In 9 formerly preeclamptic women, we examined physical fitness and hemodynamic function, before and after the training. ...
Smirk C - - 2009
OBJECTIVE: To examine pressure changes in neonatal percutaneous central venous catheters under varying laboratory conditions and to quantify the risks of rupture in clinical practice. DESIGN: We tested 27-gauge polyurethane Premicath and 24-gauge silicone ECC (both Vygon, Norristown, PA) catheters. Burst pressures were determined by applying a slowly ramped pressure ...
Kottenberg-Assenmacher Eva - - 2009
BACKGROUND: Calculation of systemic vascular resistance, used for hemodynamic decision-making, is based on central venous pressure taken as the downstream pressure. However, during circulatory arrest, arterial pressure decreases to a plateau higher than central venous pressure, the critical closing pressure (Pcrit). The authors assessed in humans undergoing arrest whether two-compartment ...
Islam M Tajul - - 2009
The open heart surgery like coronary artery bypass graft (CABG), repair of ventricular septal defect (VSD) and atrial septal defect (ASD), valve replacement need a circulatory arrest, which is normally safe under conventional hypothermia. During this time not only the heart and lungs are bypassed but also a wide range ...
Sankoff Jeffrey - - 2008
This study describes a means of assessing the external jugular venous pressure (JVP) as an indicator of normal or elevated central venous pressure (CVP). Intensive care unit patients having CVP monitoring were examined. With patients in bed, the external jugular vein (EJV) was occluded at the base of the neck ...
Choi Seong Wook - - 2008
During the use of pulsatile extracorporeal life support (pulsatile-ECLS), the patient's venous pressure near the inlet venous catheter tip must be monitored to maintain sufficient blood flow and to prevent vein collapse. However, direct measurement of the venous pressure and the estimate of suction using measured blood inflow and prepump ...
Yazigi A - - 2008
BACKGROUND: The rationale for using central venous oxygen saturation (ScvO(2)) in various clinical scenarios is that it reflects the balance between oxygen delivery (DO(2)) and demands. In this study, we evaluated the correlation between ScvO(2) and DO(2) changes (Delta Do(2), DeltaScvO(2)) in patients receiving fluid therapy following coronary surgery. We ...
Haouzi Philippe - - 2009
More than 70 years ago, Harrison and his group proposed that in the absence of pulmonary edema, an increased systemic venous pressure could be a major source of dyspnea upon exertion in cardiac patients. Harrison provided evidence that in resting animals systemic venous pressure can affect ventilatory control through afferent ...
Schummer Wolfram - - 2008
STUDY OBJECTIVE: To evaluate a new disposable syringe (Certofix PresSure Check [B Braun Melsungen AG, Melsungen, Germany]) that serves as a manometer. DESIGN: Prospective study. SETTING: University hospital's cardiac surgery suite. PATIENTS: 21 consecutive patients with continuous invasive monitoring of central venous and arterial pressures during cardiothoracic surgery. INTERVENTIONS AND ...
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