Search Results
Results 101 - 150 of 1342
1 2 3 4 5 6 7 8 9 10 >
Kahrilas P J - - 2012
The assessment of the esophagogastric junction (EGJ) is the most challenging aspect of clinical esophageal manometry. Although conventional manometric systems can be optimized toward interrogating specific aspects of the EGJ, they are too limited in recording channels and/or fidelity for a comprehensive assessment. The technological advantages inherent in high resolution ...
Catena C - - 2012
A variety of abnormalities that occur in patients with primary aldosteronism indicate the capability of elevated aldosterone to induce cardiac damage over that induced by hypertension itself. This study investigates factors that can predict structural and functional changes of the heart after treatment of primary aldosteronism in a post-hoc analysis ...
Lovelock Joshua D JD Section of Cardiology, University of Illinois at Chicago, 60612, - - 2012
Previously, we demonstrated that a deoxycorticosterone acetate (DOCA)-salt hypertensive mouse model produces cardiac oxidative stress and diastolic dysfunction with preserved systolic function. Oxidative stress has been shown to increase late inward sodium current (I(Na)), reducing the net cytosolic Ca(2+) efflux. Oxidative stress in the DOCA-salt model may increase late I(Na), ...
Grassi Guido - - 2012
Current guidelines on antihypertensive treatment emphasize the importance of combination drug treatment for achieving a full blood pressure control. The TALENT Study, involving more than 400 high-risk hypertensive patients, aimed to evaluate the efficacy and safety profile of nifedipine gastrointestinal therapeutic system (GITS) 20 mg/telmisartan 80 mg combination, as compared ...
Raff Ulrike - - 2012
OBJECTIVE: Patients with treatment resistant hypertension are at increased risk of developing cardiovascular end organ damage. The role of sodium in end organ damage is gaining interest and an independent association of sodium and cardiovascular morbidity and mortality has been described. METHODS: In an observational study including 40 patients with ...
Angeli Fabio - - 2012
Aliskiren is the first known representative of a new class of non-peptide orally active renin inhibitors that blocks the renin-angiotensin-aldosterone-system (RAAS) at its rate-limiting step. It induces a net reduction in plasma renin activity (PRA), angiotensin II and aldosterone levels. Aliskiren is effective in reducing blood pressure (BP) and is ...
Kereiakes Dean J - - 2012
J Clin Hypertens (Greenwich). 2012;14:149-157. ©2012 Wiley Periodicals, Inc. Most patients with hypertension require combination therapy in order to achieve blood pressure (BP) goals. This 40-week open-label extension of the 12-week double-blind Triple Therapy With Olmesartan Medoxomil, Amlodipine, and Hydrochlorothiazide in Hypertensive Patients Study (TRINITY) evaluated the efficacy and safety ...
Nemes Peter - - 2012
Mid-infrared laser ablation of water-rich targets at the maximum of the 2.94 μm absorption band is a two-step process initiated by phase explosion followed by recoil pressure induced material ejection. Particulates and/or droplets ejected by this high temperature high pressure process can be ionized for mass spectrometry by charged droplets ...
Stergiou George S - - 2012
For more than half a century measurement of blood pressure in the doctor's office using a mercury sphygmomanometer and the auscultatory method has been the cornerstone for hypertension management. However, due to the environmental and service issues mercury devices will not be available in the near future. As the mercury ...
Wnuk Bartosz - - 2012
The aim of the study was to evaluate the positive effects of combination of several physiotherapy methods on the respiratory function on example of a case report. Material and methods: 14 years old girl with an adolescent idiopathic scoliosis (AIS), right thoracic (primary curve, Cobb angle = 40°, AVR = ...
Everett Christopher B - - 2012
The authors present a novel approach to nonresectional therapy in major hepatic trauma utilizing intraabdominal perihepatic vacuum assisted closure (VAC) therapy in the porcine model of Grade V liver injury. A Grade V injury was created in the right lobe of the liver in a healthy pig. A Pringle ...
Boey Pui Yi - - 2012
The management of acute primary angle closure is directed at lowering the intraocular pressure and relieving pupil block. Conventional treatment involves the use of medical treatment and laser peripheral iridotomy, respectively, as a means for achieving these aims. Newer therapeutic strategies have been described that are potentially useful adjuncts or ...
Westerweel Peter E - - 2012
ACE inhibitor (ACE-I) treatment effectively inhibits proteinuria and ameliorates the course of various renal diseases. In experimental glomerulonephritis, however, angiotensin II (AngII) infusion has also been shown to be renoprotective. We evaluated the long-term (28 days) course of anti-Thy1 glomerulonephritis in animals with suppressed AngII formation by ACE-I treatment. Brown ...
Ermiş Sıtkı Samet - - 2012
Glaucoma is a chronic disease requiring lifelong treatment. Discomfort due to medications may affect patients' quality of life and may cause poor compliance, which leads to poor intraocular pressure control. To minimize the side effects of long-term treatment, preparations with lower benzalkonium chloride concentrations, preservative-free preparations and alternative preservatives have ...
Tsuji Rosana Lima Garcia - - 2012
Hypertension is a major issue in public health, and the financial costs associated with hypertension continue to increase. Cost-effectiveness studies focusing on antihypertensive drug combinations, however, have been scarce. The cost-effectiveness ratios of the traditional treatment (hydrochlorothiazide and atenolol) and the current treatment (losartan and amlodipine) were evaluated in patients ...
Gerhard Tobias - - 2012
Due to time-dependent confounding by blood pressure and differential loss to follow-up, it is difficult to estimate the effectiveness of aggressive versus conventional antihypertensive combination therapies in non-randomized comparisons. We utilized data from 22,576 hypertensive coronary artery disease patients, prospectively enrolled in the INternational VErapamil-Trandolapril STudy (INVEST). Our post-hoc analyses ...
Lu Ping - - 2012
To investigate the effects of RNA interference targeting AGT on early atherosclerotic lesion in the hypertensive state. Hypertension and atherosclerosis rats were treated with GPE nanoparticles carrying AGT shRNA. Systolic blood pressure and heart rate were measured for 2 consecutive weeks. Three days after treatment, the mRNA and protein expressions ...
Vera Grujić G Institute of Public Health of Vojvodina, Novi Sad, Serbia. - - 2012
We evaluated the prevalence of high blood pressure and the level of awareness, treatment, and control of hypertension in a Serbian population. A cross-sectional study of an adult population was carried out across Serbia in 2006. The study involved 14 204 adults aged 20 years or older. Interviews and measurements ...
Liew Phui-Ly PL Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, - - 2012
Summary: Background: Nonalcoholic fatty liver disease (NAFLD) is associated with obesity. We retrospectively studied the clinicopathology and different hepatic adipocytokine expressions between nonalcoholic steatohepatitis (NASH) and non-NASH in morbid obesity.Methods: We enrolled 40 patients undergoing liver biopsy during bariatric surgery. We analyzed hepatic mRNA and immunohistochemistry of TNF-α, leptin, adiponectin ...
Robertson E V EV Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK. - - 2012
The high resolution esophageal manometry system manufactured by Sierra Scientific Instruments is widely used. The technology is liable to 'thermal drift', a change in measured pressure due to change in temperature. This study aims to characterize 'thermal drift' and minimize its impact. Response of the system to immediate temperature change ...
Sahandi R - - 2011
Accurate fitting of a lower-limb prosthetic socket is the most important factor affecting amputee satisfaction and rehabilitation. The technology is now available to allow real-time monitoring of in-service pressure distribution of prosthetic limbs. This paper proposes a remote interfacial pressure monitoring system necessary for the assessment of fit. The suitability ...
Bièche Clémence - - 2011
Campylobacter jejuni is one of the most intriguing human foodborne bacterial pathogen. Its survival throughout the food processing chain and its pathogenesis mechanisms in humans remain enigmatic. Living in the animal guts and particularly in avian intestine as a commensal bacterium, this microorganism is frequently isolated from meat products. Ultra ...
Kamath Nivedita - - 2011
The study was done to validate the use of automated devices (Datascope Duo) as a screening tool for measuring blood pressure. A cross sectional study was conducted in school children from urban slums of Bangalore. Blood pressure was recorded according to standard guidelines using a mercury sphygmomanometer and an automated ...
Zoremba N - - 2011
Pressure infusion devices are used in clinical practice to apply large volumes of fluid over a short period of time. Although air infusion is a major complication, they have limited capability to detect and remove air during pressure infusion. In this investigation, we tested the air elimination capabilities of the ...
Freeman Emily - - 2011
The minimization of pre-analytical variables in sample preparation is imperative for successful discovery-driven and translational research involving large-scale biomolecular profiling. Here we demonstrate a novel technique using high hydrostatic pressure in addition to several chaotropes and solvents to maximize efficiency of both cell lysis and enzymatic digestion while minimizing the ...
de Greeff Annemarie - - 2011
OBJECTIVE: The Tensoval duo control device uses a novel combination of auscultatory and oscillometric technology to measure blood pressure. We assessed the accuracy of this device in a South African adult population according to the International Protocol of the European Society of Hypertension. METHODS: Ethical approval was obtained and 33 ...
Sollier Elodie - - 2011
Multiple methods of fabrication exist for microfluidic devices, with different advantages depending on the end goal of industrial mass production or rapid prototyping for the research laboratory. Polydimethylsiloxane (PDMS) has been the mainstay for rapid prototyping in the academic microfluidics community, because of its low cost, robustness and straightforward fabrication, ...
Blute Jr Michael L - - 2011
Study Type - Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? ••, ••, ••, ••, ••, ••. ••, ••, ••, ••, ••, ••. OBJECTIVE: • To determine the pressure-flow characteristics of neobladders created in various configurations that may be constructed intra-abdominally. Complete ...
Barawkar Dinesh A DA Drug Discovery Facility, Advinus Therapeutics Limited , Quantum Towers, Plot-9, Phase-I, Rajiv Gandhi InfoTech Park, Hinjewadi, Pune 411 057, - - 2011
l-2-Hydroxy acid oxidase (Hao2) is a peroxisomal enzyme with predominant expression in the liver and kidney. Hao2 was recently identified as a candidate gene for blood pressure quantitative trait locus in rats. To investigate a pharmacological role of Hao2 in the management of blood pressure, selective Hao2 inhibitors were developed. ...
Knight Peter A - - 2011
A readily applied and reliable means to create and close transapical wound access sites through a small intercostal opening could benefit many cardiac patients. Using relevant surgical tissue models, this research evaluated a new approach to enable single-port transapical wound site closure toward the eventual development of safe percutaneous access ...
Bhattarai B - - 2011
Post obstructive pulmonary edema (POPE) also known as Negative pressure pulmonary edema (NPPE)is potentially life threatening complication. It occurs in about 0.1% of anesthetics and is related to upper airway obstruction. Two types have been described in literature. Different etiology has been attributed to development of Negative pressure pulmonary edema. ...
Rouseff Daniel - - 2011
The 2009 cooperative array performance experiment (CAPE'09) was designed to compare performance between vector- and pressure-sensor arrays. The experiment was a joint effort of Chinese and American investigators; both arrays were designed and assembled by the Hangzhou Applied Acoustics Research Institute (HAARI), while the source systems and signal processing/recording systems ...
Yadav Rahul - - 2011
During one lung ventilation (OLV) hypoxemia may occur due to ventilation-perfusion mismatch. It can be prevented with application of ventilation strategy that prevents atelectasis while minimally impairing perfusion of the dependant lung. Here, two cases are reported who required OLV and in whom hypoxemia could be prevented with the application ...
Orth Antony - - 2011
We demonstrate a novel optical pressure measurement platform for microfluidics. The pressure sensors operate as pneumatically-tunable microlenses whose focal lengths vary with pressure. We show that pneumatic lens arrays can be used to perform sensitive multiplexed pressure measurements in microfluidic channels.
Melchionda Fraia - - 2011
We describe 2 cases of children with malignant disease who developed severe mucositis with perineal necrotizing fasciitis during severe neutropenia after chemotherapy. Treatment with topical negative pressure therapy with silver foam dressing, together with large spectrum antibiotics, resolved the problem with complete closure of the wound after 30 and 36 ...
Gaddum Nicholas Richard - - 2011
The use of rotary left ventricular assist devices (LVADs) has extended to destination and recovery therapy for end-stage heart failure. Incidence of right ventricular failure while on LVAD support requires a second device be implanted to support the failing right ventricle. Without a commercially available implantable rotary right ventricular assist ...
Antlanger Moritz - - 2011
We have investigated the possibility of decorating, using a bottom-up strategy, patchy particles in such a way that they self-assemble in (two-dimensional) Archimedean tilings. Except for the trihexagonal tiling, we have identified conditions under which this is indeed possible. The more compact tilings, i.e., the elongated triangular and the snub ...
Heckel Kai - - 2011
OBJECTIVE:: According to Fick's law of diffusion, gas exchange depends on the size and thickness of the blood perfused alveolocapillary membrane. Impairment of either one is tenuous. No data are available concerning the impact of hydroxyethyl starches and saline on pulmonary microperfusion and gas exchange during systemic inflammation. DESIGN:: Prospective, ...
Stergiou G S - - 2011
This study validated a hybrid mercury-free device as a replacement of the mercury sphygmomanometer for professional use, and also as a standard for future validations. A validation study was performed according to the European Society of Hypertension International Protocol 2010 (ESH-IP) in 33 subjects using simultaneous blood pressure (BP) measurements. ...
Senocq François - - 2011
Chemical vapour deposition and atomic layer deposition using precursors that are solids at ambient temperature and pressure present challenges due to the often low saturating vapour pressure of these compounds. Additional concerns arise from the difficulty to maintain a reproducible and stable precursor flow rate to the deposition chamber and ...
Lovibond Kate K National Clinical Guideline Centre, Royal College of Physicians, London, - - 2011
The diagnosis of hypertension has traditionally been based on blood-pressure measurements in the clinic, but home and ambulatory measurements better correlate with cardiovascular outcome, and ambulatory monitoring is more accurate than both clinic and home monitoring in diagnosing hypertension. We aimed to compare the cost-effectiveness of different diagnostic strategies for ...
Napoli Anthony M - - 2012
Clinical assessment and vital signs are poor predictors of the overall hemodynamic state. Optimal measurement of the response to fluid resuscitation and hemodynamics has previously required invasive measurement with radial and pulmonary artery catheterization. Newer noninvasive resuscitation technology offers the hope of more accurately and safely monitoring a broader range ...
Lemson Joris - - 2011
Circulatory shock is an important cause of pediatric morbidity and mortality and requires early recognition and prompt institution of adequate treatment protocols. Unfortunately, the hemodynamic status of the critically ill child is poorly reflected by physical examination, heart rate, blood pressure, or laboratory blood tests. Advanced hemodynamic monitoring consists, among ...
Voss A - - 2011
Due to recent advances in technology extensive cardiovascular monitoring is widely introduced today. An essential component of cardiovascular monitoring is the analysis of several biosignals as electrocardiogram, blood pressure and other vital signs. This manuscript provides an overview about several application fields of cardiovascular monitoring with the main focus on ...
Wheeler Jason W - - 2011
The ability to chronically monitor pressure at the prosthetic socket/residual limb interface could provide important data to the research and clinical communities. With this application in mind, we describe a novel type of sensor which consists of a MEMS pressure sensor and custom electronics packaged in a fluid-filled bubble. The ...
Sepulveda A T - - 2011
A new approach for the design and fabrication of a highly flexible blood pressure sensor is introduced in this paper. The goal is to measure the pressure within an aneurysm sac for post-endovascular aneurysms repair (EVAR) surveillance. Biocompatible polydimethylsiloxane (PDMS) membranes with embedded aligned carbon nanotubes (CNTs) are used to ...
Ogawa M - - 2011
The concept of tailored bioinstrumentation using rapid prototyping and three-dimensional CAD (3D-CAD) was proposed. This concept is to make individually designed and fabricated sensor unit to attach human body. Within the proposed concept, cuff-units for continuous blood pressure measurement were individually designed using 3D-CAD and fabricated automatically. As the result, ...
Dueñas-Garcia O F - - 2011
Physicians have used fetal heart monitoring for 300 years but it has faced a revolution in the last 50 years after the incorporation of new devices and the discovery of the normal patterns of labour. Dr Caldeyro Barcia in Uruguay was one of the pioneers of the development of intrauterine ...
Stevens Michael Charles - - 2011
A physiological control system was developed for a rotary left ventricular assist device (LVAD) in which the target pump flow rate (LVADQ) was set as a function of left atrial pressure (LAP), mimicking the Frank-Starling mechanism. The control strategy was implemented using linear PID control and was evaluated in a ...
De Rossi S M M - - 2011
In this work, we present the development of an in-shoe device to monitor plantar pressure distribution for gait analysis. The device consists in a matrix of 64 sensitive elements, integrated with in-shoe electronics and battery which provide an high-frequency data acquisition, wireless transmission and an average autonomy of 7 hours ...
1 2 3 4 5 6 7 8 9 10 >