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Xu Jie - - 2013
Prebiotics, probiotics, or synbiotics can be used as means to regulate the microbiota to exert preventative or beneficial effects to the host. However, not much is known about the effect of the gut microbiota on hypertension which is a major risk factor of cardiovascular disease and also a symptom of ...
Latea Luminita - - 2013
Non-alcoholic fatty liver disease (NAFLD) is considered the most common liver disease affecting 15-25% of the general population. The aim of this study was to investigate the prevalence of NAFLD and the relationship between insulin sensitivity and NAFLD in grade III high and very high cardiovascular additional risk essential hypertensive ...
Hilal-Alnaqbi Ali - - 2013
Bioartificial liver support provides a bridge to transplantation which is at present the only proven specific treatment for acute liver failure. In this paper, a novel multi-coaxial hollow fiber bioreactor so-called "Fibre-in-Fibre FIF Bioartificial liver device" with three compartments is experimentally and mathematically studied. The mathematical model in this paper ...
Ehnert Sabrina S Eberhard Karls Universität Tübingen, BG Trauma Center, Tübingen, - - 2013
Patients with alcoholic liver disease (ALD) often suffer from high blood pressure and rely on antihypertensive treatment. Certain antihypertensives may influence progression of chronic liver disease. Therefore, the aim of this study is to investigate the impact of the commonly used antihypertensives amlodipine, captopril, furosemide, metoprolol, propranolol, and spironolactone on ...
Kora Shin-Ichi - - 2012
AIM: To elucidate whether warming may reduce the viscosity of miriplatin-lipiodol suspension (MPT/LPD) and also the injection pressure through microcatheters, for potential use as a chemotherapeutic agent of transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC). METHODS: Viscosity of MPT/LPD prepared at on-label dose was measured in vitro at 25°C, 30°C, ...
Reiberger Thomas - - 2012
INTRODUCTION: We evaluated the effects of nebivolol, a third generation beta-blocker capable of increasing NO-bioavailability on portal pressure, and on splachnic and systemic haemodynamics in a cirrhotic portal hypertensive rat model. METHODS: Male Sprague-Dawley rats underwent sham operation (SO) or bile duct ligation (BDL). When cirrhosis was fully developed, the ...
Agasti Ananta Kumar - - 2012
OBJECTIVE: This study aimed to compare the efficacy of losartan, an angiotensin II receptor antagonist, vs propranolol on portal hypertension in patients with decompensated chronic liver disease. METHODS: Thirty patients with Child B cirrhosis with large varices without any prior therapy for portal hypertension were randomized to either losartan (n ...
Rose Steven C - - 2012
PURPOSE: The purpose of this work was to evaluate blood pressure changes caused by deployment of the Surefire antireflux expandable tip. The pressure measurements are relevant because they imply changes in hepatoenteric arterial blood flow within this liver compartment during hepatic artery delivery of cytotoxic agents. METHODS: After positioning the ...
Krishnamoorthy V - - 2012
Elevation in intracranial pressure (ICP) secondary to cerebral edema is a major contributor to morbidity and mortality in acute liver failure. In addition, invasive intracranial pressure monitoring in this setting is controversial, as coagulopathy predisposes to hemorrhagic complications. In this case report, the authors describe the novel use on optic ...
Gilglioni Eduardo Hideo - - 2012
Estrogen deficiency is associated with aging and increases the incidence of metabolic syndrome and hypertension. In this study, the effects of tibolone, a synthetic steroid, on the cardiovascular system, liver lipid metabolism, and redox status were evaluated, in ovariectomized (OVX) rats with renovascular hypertension (two-kidneys, one-clip, OVX + 2K1C). This ...
Oka Tatsujiro - - 2012
OBJECTIVES: Patients may develop liver dysfunction, including liver fibrosis, over the long term following Fontan procedure. Therefore, early detection of liver dysfunction is essential to identify those patients who are at risk. We evaluated various laboratory parameters, including liver biochemical markers, hepatic echography findings, and cardiac catheterization outcomes, at an ...
Otsuka Yuichiro - - 2012
Laparoscopic hepatectomy (LH) has become popular as a surgical treatment for liver diseases, and numerous recent studies indicate that it is safe and has advantages in selected patients. Because of the magnified view offered by the laparoscope under pneumoperitoneal pressure, LH results in less bleeding than open laparotomy. However, gas ...
Hsieh Yun-Cheng - - 2012
It is a well-accepted fact that angiotensin II (Ang II) contributes to increased vascular tone in cirrhotic livers. However, aliskiren attenuates the effect of Ang II through direct renin inhibition. Our study aimed to evaluate the effects of aliskiren on portal pressure and intrahepatic resistance in bile duct ligated (BDL) ...
Ziegelhöffer A - - 2012
This study deals with changes, induced by hypertension and its treatment, in the function and properties of mitochondria in the heart and kidneys. Male, 16-week-old hypertensive rats were allocated to 3 groups: (i) animals treated daily for 4 weeks with captopril (CAP, 80 mg·(kg body mass)(-1), n = 45), (ii) animals treated ...
Nural Serkan - - 2012
We aimed to compare serum levels of the inflammatory mediators including C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), and asymmetric dimethylarginine (ADMA) in chronic obstructive pulmonary disease (COPD), obstructive sleep apnea syndrome (OSAS), and their coexistence called overlap syndrome (OVS). In addition, we planned to investigate changes of these mediators ...
Kishi Takuya T Department of Advanced Therapeutics for Cardiovascular Diseases, Kyushu University Graduate School of Medical Sciences, Fukuoka, - - 2012
Renin-angiotensin system inhibitors are preferred for the treatment of hypertension with metabolic syndrome (MetS). Underlying endothelial dysfunction and sympathetic nervous system (SNS) activation are critically involved in the pathogenesis of hypertension in MetS. We investigated whether treatment with angiotensin II type 1 receptor blockers (ARBs) improves endothelial and autonomic function ...
Tünsmeyer Julia - - 2012
Objective  To determine the cardiovascular effects of a proprietary l-methadone/fenpipramide combination (Polamivet) alone and in addition to acepromazine in dogs. Study design  Prospective, randomized, experimental crossover study. Animals  Five adult healthy Beagle dogs (one male and four females, weighing 12.8-16.4 kg). Methods  Dogs were instrumented for haemodynamic measurements whilst anaesthetized with ...
Garner Rachel S - - 2012
ContextPrevious studies have correlated poor neurological outcomes with hypotension. Treatment of hypotension in very low birthweight (VLBW) infants is common, and most often is based solely on the blood pressure measurement. Whether treatment improves cerebral oxygenation is unclear.ObjectiveTo determine if treatment of hypotension in VLBW neonates results in an increase ...
Mancia Giuseppe - - 2012
BACKGROUND: In high cardiovascular risk treated hypertensive patients the incidence of cardiovascular events has been reported to relate to visit-to-visit blood pressure (BP) variability. We investigated whether visit-to-visit BP variability is prognostically important in mild-to-moderate treated hypertensives in whom treatment aims at avoiding events but also at preventing or delaying ...
Knox Cartwright Nathaniel E - - 2012
To quantify the magnitude of the stiffening effect of corneal cross-linking (CXL) by studying intact human corneas exposed to physiological pressure transients. Nine organ-cultured human corneas mounted in artificial anterior chambers were studied. A radial shearing speckle pattern interferometer was used to measure changes in corneal strain following an increase ...
Arima Hisatomi - - 2012
BACKGROUND AND PURPOSE: The INTEnsive blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT) pilot study showed that early intensive blood pressure-lowering can attenuate hematoma growth in acute intracerebral hemorrhage. The present analysis aimed to determine the treatment effects on hematoma growth by time from intracerebral hemorrhage onset to randomization. ...
Ye Mu - - 2012
Several recent outbreaks associated with oysters have heightened safety concerns of raw shellfish consumptions, with the majority being attributed to Vibrio spp. The objective of this study was to determine the effect of high-hydrostatic pressure (HHP) followed by mild heating on the inactivation of Vibrio parahaemolyticus and Vibrio vulnificus in ...
Sakellaridis Timothy - - 2012
Re-expansion pulmonary edema (REPE) is a rare complication of treatment of spontaneous pneumothorax or large pleural effusions. As a complication of spontaneous pneumothorax treatment, only few cases are documented, and even fewer document the role of non-invasive continuous positive airway pressure mechanical ventilation for treatment of this rare entity. We ...
Matthesen Solveig Klok - - 2012
We wanted to test the hypothesis that treatment with amiloride or spironolactone reduced ambulatory (ABP) and central blood pressure (CBP) and that tubular transport via ENaCγ and AQP2 was increased after furosemide treatment. During baseline conditions, there were no differences in ABP, CBP, renal tubular function, or plasma concentrations of ...
Mabin Tom - - 2012
Aims: To evaluate a novel modality utilising ultrasound for renal denervation designed to reduce the duration of the intervention as well as to increase the consistency of the clinical outcome. Methods and results: Eleven consecutive patients suffering from resistant hypertension as defined by the ESH-ESC guidelines were treated by transcatheter ...
Rizk Awad - - 2012
Objective-To investigate the hormonal, metabolic, and cardiorespiratory effects of xylazine hydrochloride on dairy cows undergoing lateral recumbency and claw trimming. Design-Prospective crossover study. Animals-6 healthy Holstein-Friesian cows. Procedures-Cows were treated with xylazine (0.05 mg/kg [0.023 mg/lb], IM) or an equal volume of saline (0.9% NaCl) solution 15 minutes before being ...
Krousel-Wood Marie - - 2012
J Clin Hypertens (Greenwich). 2012; 14:277-283. ©2012 Wiley Periodicals, Inc. Medication prescribing practice changed following the publications of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) in 2002 and the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure ...
Zhao Xiao-hong - - 2012
To quantify the changes in blood glucose, blood lipids, blood pressure, and the intima-media thickness (IMT) of large arteries in patients with new-onset type 2 diabetes mellitus who received either intensive multifactorial treatment or conventional treatment. Two-hundred and ten patients with new-onset type 2 diabetes mellitus were randomly assigned to ...
Moore Stan G - - 2012
The recently developed chemical potential perturbation (CPP) method [S. G. Moore and D. R. Wheeler, J. Chem. Phys. 134, 114514 (2011)] is extended to the lattice (Ewald) sum treatment of intermolecular potentials. The CPP method predicts chemical potentials for a range of composition points using the local (position-dependent) pressure tensor ...
Amaiden Marina R - - 2012
OBJECTIVE:: To test the hypothesis that erythrocyte deformability is influenced by changes in the content of membrane tubulin (Mem-tub). METHODS AND RESULTS:: Human erythrocytes contain tubulin distributed in three pools (membrane, sedimentable, soluble). Erythrocytes from hypertensive humans have a higher proportion of Mem-tub. Increased Mem-tub content in hypertensive patients was ...
Mancia Giuseppe - - 2012
BACKGROUND:: Recent studies have reported that in patients under antihypertensive treatment visit-to-visit (or long-term) variability of clinic blood pressure (BP) within a given patient has an independent prognostic significance. Partly based on between-patient dispersion of BP values during treatment (interindividual variability) it has also been reported that long-term clinic BP ...
Byun Sung Hye - - 2012
A 41-year-old male patient presented with idiopathic persistent hiccups. The hiccups did not respond to pharmacologic treatments including cisapride, omeprazole, and baclofen. Phrenic nerve block was also ineffective. However, the persistent hiccups were successfully treated with short-term positive pressure ventilation using a short-acting muscle relaxant.
Tabla R - - 2012
The combined effect of bacteriophages, vB_SauS-phi-IPLA35 (phiIPLA35) and vB_SauS-phi-IPLA88 (phiIPLA88), and high hydrostatic pressure (HHP) on Staphylococcus aureus Sa9 was evaluated in pasteurized whole milk under a simulated cold chain break, which was simulated by incubation of milk at 25°C for 48h. Four-hundred MPa was found to be the most ...
Fujiwara Wakaya - - 2012
Previous studies have shown highly effective lowering of blood pressure with thiazide diuretics in combination with angiotensin receptor blockers. However, thiazide diuretics may cause the development of diabetes and abnormal lipid metabolism. Little is known as to whether dysmetabolic potential of thiazide diuretics could be neutralized when adding angiotensin receptor ...
Xu Huifeng - - 2012
OBJECTIVE: To determine whether the antihypertensive and vascular protective effects of short-term treatment with lercanidipine, a calcium channel blocker, are modulated by the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism. METHODS: In a self-controlled study, a total of 143 essential hypertensive patients, all permanent residents of Shanghai, were included. All of them ...
Rodríguez Juan Morgaz - - 2012
Objective  To compare the cardiorespiratory effects and quality of induction of and recovery from anaesthesia following etomidate or alphaxalone-HPCD IV. Study design  Randomized 'blinded' cross-over study. Twenty-four hours was allowed between phases. Animals  Eight healthy adult Beagles (four male, four female). Methods  Dogs were anaesthetized with sevoflurane for instrumentation, then allowed ...
Kahrilas P J - - 2012
The assessment of the esophagogastric junction (EGJ) is the most challenging aspect of clinical esophageal manometry. Although conventional manometric systems can be optimized toward interrogating specific aspects of the EGJ, they are too limited in recording channels and/or fidelity for a comprehensive assessment. The technological advantages inherent in high resolution ...
Catena C - - 2012
A variety of abnormalities that occur in patients with primary aldosteronism indicate the capability of elevated aldosterone to induce cardiac damage over that induced by hypertension itself. This study investigates factors that can predict structural and functional changes of the heart after treatment of primary aldosteronism in a post-hoc analysis ...
Lovelock Joshua D JD Section of Cardiology, University of Illinois at Chicago, 60612, - - 2012
Previously, we demonstrated that a deoxycorticosterone acetate (DOCA)-salt hypertensive mouse model produces cardiac oxidative stress and diastolic dysfunction with preserved systolic function. Oxidative stress has been shown to increase late inward sodium current (I(Na)), reducing the net cytosolic Ca(2+) efflux. Oxidative stress in the DOCA-salt model may increase late I(Na), ...
Grassi Guido - - 2012
Current guidelines on antihypertensive treatment emphasize the importance of combination drug treatment for achieving a full blood pressure control. The TALENT Study, involving more than 400 high-risk hypertensive patients, aimed to evaluate the efficacy and safety profile of nifedipine gastrointestinal therapeutic system (GITS) 20 mg/telmisartan 80 mg combination, as compared ...
Raff Ulrike - - 2012
OBJECTIVE: Patients with treatment resistant hypertension are at increased risk of developing cardiovascular end organ damage. The role of sodium in end organ damage is gaining interest and an independent association of sodium and cardiovascular morbidity and mortality has been described. METHODS: In an observational study including 40 patients with ...
Angeli Fabio - - 2012
Aliskiren is the first known representative of a new class of non-peptide orally active renin inhibitors that blocks the renin-angiotensin-aldosterone-system (RAAS) at its rate-limiting step. It induces a net reduction in plasma renin activity (PRA), angiotensin II and aldosterone levels. Aliskiren is effective in reducing blood pressure (BP) and is ...
Kereiakes Dean J - - 2012
J Clin Hypertens (Greenwich). 2012;14:149-157. ©2012 Wiley Periodicals, Inc. Most patients with hypertension require combination therapy in order to achieve blood pressure (BP) goals. This 40-week open-label extension of the 12-week double-blind Triple Therapy With Olmesartan Medoxomil, Amlodipine, and Hydrochlorothiazide in Hypertensive Patients Study (TRINITY) evaluated the efficacy and safety ...
Nemes Peter - - 2012
Mid-infrared laser ablation of water-rich targets at the maximum of the 2.94 μm absorption band is a two-step process initiated by phase explosion followed by recoil pressure induced material ejection. Particulates and/or droplets ejected by this high temperature high pressure process can be ionized for mass spectrometry by charged droplets ...
Stergiou George S - - 2012
For more than half a century measurement of blood pressure in the doctor's office using a mercury sphygmomanometer and the auscultatory method has been the cornerstone for hypertension management. However, due to the environmental and service issues mercury devices will not be available in the near future. As the mercury ...
Wnuk Bartosz - - 2012
The aim of the study was to evaluate the positive effects of combination of several physiotherapy methods on the respiratory function on example of a case report. Material and methods: 14 years old girl with an adolescent idiopathic scoliosis (AIS), right thoracic (primary curve, Cobb angle = 40°, AVR = ...
Everett Christopher B - - 2012
The authors present a novel approach to nonresectional therapy in major hepatic trauma utilizing intraabdominal perihepatic vacuum assisted closure (VAC) therapy in the porcine model of Grade V liver injury. A Grade V injury was created in the right lobe of the liver in a healthy pig. A Pringle ...
Boey Pui Yi - - 2012
The management of acute primary angle closure is directed at lowering the intraocular pressure and relieving pupil block. Conventional treatment involves the use of medical treatment and laser peripheral iridotomy, respectively, as a means for achieving these aims. Newer therapeutic strategies have been described that are potentially useful adjuncts or ...
Westerweel Peter E - - 2012
ACE inhibitor (ACE-I) treatment effectively inhibits proteinuria and ameliorates the course of various renal diseases. In experimental glomerulonephritis, however, angiotensin II (AngII) infusion has also been shown to be renoprotective. We evaluated the long-term (28 days) course of anti-Thy1 glomerulonephritis in animals with suppressed AngII formation by ACE-I treatment. Brown ...
Ermiş Sıtkı Samet - - 2012
Glaucoma is a chronic disease requiring lifelong treatment. Discomfort due to medications may affect patients' quality of life and may cause poor compliance, which leads to poor intraocular pressure control. To minimize the side effects of long-term treatment, preparations with lower benzalkonium chloride concentrations, preservative-free preparations and alternative preservatives have ...
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