Search Results
Results 201 - 250 of 1831
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Erdmann Erland - - 2012
AimsCinaciguat (BAY 58-2667) is a novel soluble guanylate cyclase activator. This study evaluated the haemodynamic effect and safety of cinaciguat added to standard therapy in patients with acute decompensated heart failure (ADHF).Methods and resultsIn this placebo-controlled, phase IIb study (NCT00559650), 139 patients admitted with ADHF, pulmonary capillary wedge pressure (PCWP) ≥18 ...
Ryu J H - - 2012
Femoral veins are commonly used as a relatively safe alternative route for central venous cannulation. Several maneuvers are used to increase the cross-sectional area of the vein. In this study, we assessed the effect of positive end-expiratory pressure (PEEP) on the cross-sectional area (CSA) of femoral veins, using ultrasound in ...
Georgescu M - - 2012
OBJECTIVE: The impact of non-invasive positive pressure ventilation (NIPPV), which is a combination of inspiratory positive airway pressure (IPAP) and positive end expiratory pressure (PEEP), on the effectiveness of preoxygenation in obese patients was evaluated. DESIGN: Randomized, controlled, double blinded, crossover study comparing NIPPV vs. tidal volume breathing (TVB) with ...
Deguchi Ichiro I Department of Neurology and Cerebrovascular Medicine, International Medical Center, Saitama Medical University, Hidaka, Hidaka, Japan. - - 2012
This prospective study examined the effects of telmisartan, an angiotensin II type I receptor blocker with peroxisome proliferator-activated receptor gamma agonistic action, on blood pressure (BP) control and cerebral circulation in hypertensive patients with chronic-stage stroke. Telmisartan (40 mg per day) was administered to 10 patients with systolic BP (SBP) 140 mm Hg ...
Maas Jacinta J - - 2012
BACKGROUND:Mean systemic filling pressure (Pmsf) can be measured at the bedside with minimally invasive monitoring in ventilator-dependent patients using inspiratory hold maneuvers (Pmsf(hold)) as the zero flow intercept of cardiac output (CO) to central venous pressure (CVP) relation. We compared Pmsf(hold) with arm vascular equilibrium pressure during vascular occlusion (Pmsf(arm)) ...
Pinto Sharrel L - - 2012
OBJECTIVE To measure the impact of an employer-sponsored, pharmacist-provided medication therapy management (MTM) program on clinical outcomes and social and process measures for patients with diabetes with or without associated comorbid conditions. METHODS Prospective longitudinal study that took place at seven independent pharmacies in Lucas County, OH. A total of ...
Chalari Eleftheria - - 2012
Vital signs are indicators of a patient presenting to an emergency department (ED). Abnormal vital signs have been associated with an increased likelihood of admission to the hospital. Physicians have long recognized the importance of vital sign observations, and vital sign measurement has proven to be useful for detecting serious ...
Aguiar Patricia M - - 2012
OBJECTIVE To evaluate the effect of a pilot pharmaceutical care program developed for elderly patients with uncontrolled hypertension. METHODS Nonrandomized single intervention pre/posttest blood pressure study in a community pharmacy in Aracaju, Brazil. This study enrolled elderly patients diagnosed with essential hypertension and uncontrolled blood pressure. Monthly visits were scheduled ...
Oliveira-Costa Clarice Daniele Alves de - - 2012
To determine the utility of pulse pressure variation (ΔRESP PP) in predicting fluid responsiveness in patients ventilated with low tidal volumes (V T) and to investigate whether a lower ΔRESP PP cut-off value should be used when patients are ventilated with low tidal volumes. This cross-sectional observational study included 37 ...
Sánchez-Porras Renán - - 2012
BACKGROUND: Cerebral autoregulation and, consequently, cerebrovascular pressure reactivity, can be disturbed after traumatic brain injury (TBI). Continuous monitoring of autoregulation has shown its clinical importance as an independent predictor of neurological outcome. The cerebral pressure reactivity index (PRx) reflects that changes in seconds of cerebrovascular reactivity have prognostic significance. Using ...
Michas Fotios - - 2012
OBJECTIVES: Baroreceptor reflex sensitivity (BRS) is an important factor in the homeostatic regulation of the cardiovascular system. Arterial stiffening also provides direct evidence of target organ damage in hypertensive patients. The aim of the present study was to evaluate a possible association between BRS and pulse wave velocity (PWV) in ...
Wijkman Magnus - - 2012
OBJECTIVES: Both ambulatory and central blood pressures have been reported to correlate more closely than office blood pressure with left ventricular mass index (LVMI). The aim of this study was to test whether ambulatory systolic blood pressure (SBP) predicts LVMI independent of central SBP in patients with type 2 diabetes. ...
Ghio Stefano - - 2012
AIMS: Pulmonary hypertension (PH) due to systolic left ventricular dysfunction (PH-sLVD) frequently complicates heart failure (HF), and greatly worsens the prognosis of patients with sLVD, but as yet has no approved treatment. The LEPHT study aims to characterize the haemodynamic profile, safety, tolerability, and pharmacokinetic profile of riociguat (BAY 63-2521), ...
Daikuhara Hiroyuki - - 2012
Angiotensin II receptor blockers (ARB) are often co-administered with a calcium channel blocker (CCB) for treating hypertension. In this open-label randomised study, untreated diabetic hypertensive patients were randomised to receive either olmesartan 20 mg/day or candesartan 8 mg/day for 12 weeks. Patients with blood pressure exceeding 130/80 mm Hg received ...
Robinson Bruce M BM Arbor Research Collaborative for Health, Ann Arbor, MI, USA. - - 2012
KDOQI practice guidelines recommend predialysis blood pressure <140/90 mm Hg; however, most prior studies had found elevated mortality with low, not high, systolic blood pressure. This is possibly due to unmeasured confounders affecting systolic blood pressure and mortality. To lessen this bias, we analyzed 24,525 patients by Cox regression models adjusted ...
Argulian Edgar - - 2012
Subacute (medical) tamponade develops over a period of days or even weeks. Previous studies have shown that subacute tamponade is uncommonly associated with hypotension. On the contrary, many of those patients are indeed hypertensive at initial presentation. We sought to determine the prevalence and predictors of hypertensive cardiac tamponade and ...
Alexánderson Erick - - 2012
BACKGROUND: Essential hypertension is one of the main risk factors for the development of coronary artery disease (CAD). Hypertension causes endothelial dysfunction which is considered an early sign for the development of CAD. Positron emission tomography is a non-invasive imaging technique that measures myocardial blood flow (MBF), allowing us to ...
Sladowska-Kozłowska Joanna - - 2012
The relation between primary hypertension (PH), target organ damage (TOD) and oxidative stress (SOX) is not known. We assessed SOX in 86 children with PH before and after 12 months of standard non-pharmacological and pharmacological therapy based on renin-angiotensin system blockade. Patients with left ventricular hypertrophy (LVH) and with carotid ...
de la Sierra Alejandro - - 2012
Clinical characteristics of resistant hypertensive patients in comparison to controlled patients have not been fully investigated in large cohorts. The aim of the study was to evaluate clinical differences, target organ damage and ambulatory blood pressure monitoring in resistant hypertensive patients and patients controlled on three or less drugs. In ...
Hwang Jung-Won - - 2012
Arterial stiffening may affect regional myocardial function in hypertensive patients with normal ejection fraction (EF). Brachial-ankle pulse wave velocity (PWV) was measured in 70 patients, of mean age 48 ± 14 years, with untreated hypertension and EF > 55%. Using two-dimensional-speckle tracking echocardiography, we measured longitudinal and circumferential strain (ε) ...
Post I L - - 2012
Anastomotic leakage is a serious complication after colorectal surgery. Pre- and intraoperative factors may contribute to failure of colorectal anastomosis. In this study we have tried to determine risk factors for anastomotic leakage, with special emphasis on intraoperative blood pressure changes. During a 24-month period, patients receiving a colorectal anastomosis ...
Geske Jeffrey B JB Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, College of Medicine, Rochester, Minnesota 55905, - - 2012
This study examined the relationship between peak-to-peak (common invasive measurement), peak instantaneous (common Doppler measurement), and mean pressure gradients in patients with hypertrophic cardiomyopathy (HCM) and aortic stenosis (AS). In patients with AS, the peak-to-peak gradient and peak instantaneous gradient are discrepant, and the mean gradient best represents obstruction severity. ...
Wang Wei - - 2012
Objectives:  The surgical cure rate of patients with aldosterone-producing adenoma varies widely, and causes of persistent hypertension are not completely established. The objective of this study was to assess the blood pressure outcome in patients after retroperitoneoscopic adrenalectomy, and to analyze the CYP11B2 344 C/T polymorphism and any factors associated ...
Miyake1 Hiroji - - 2012
BACKGROUND:: Management of overdrainage complications in shunted patients with idiopathic normal pressure hydrocephalus (INPH) remains a difficult task despite the use of programmable pressure valves (PPVs). OBJECTIVE:: To assess the usefulness of a quick reference table (QRT) algorithm for achieving a suitable initial PPV setting in INPH patients who participated ...
Wierzbicki Karol - - 2012
INTRODUCTION: Heart failure is a growing health care problem. Secondary  pulmonary hypertension is usually observed in patients with end-stage cardiomyopathy. OBJECTIVES: The main purpose was to evaluate the relationship between N-terminal prohormone of brain natriuretic peptide (NT-pro BNP) levels and markers of secondary venous pulmonary hypertension in patients referred for heart transplantation. ...
Kırış Abdulkadir - - 2012
Objectives: Left ventricular (LV) systolic synchrony, defined as simultaneous peak contractions of corresponding cardiac segments, is well documented to be impaired in hypertension but its effect on LV function is not clear. The aim of this study was to assess the impacts of LV systolic dyssynchrony on LV function in ...
Jiang Liping - - 2012
PURPOSE:: The purpose of this study was to explore the expression of apoptotic factors in stage III pressure ulcers and explain their effects on wound healing. SUBJECTS AND SETTING:: The sample comprised 8 patients with stage III pressure ulcers, along with 4 volunteers with normal skin who were undergoing elective ...
Indra Tomás - - 2012
We evaluated the influence of increased intravascular volume on the heart anatomy in salt-sensitive types of hypertension, represented by primary aldosteronism (PA) and low-renin essential hypertension (LREH). Echocardiography was performed in 128 males with moderate to severe or resistant hypertension: 44 patients had PA, 40 patients had LREH and 44 ...
Massierer Daniela - - 2012
BACKGROUND: In face of variable definitions and sampling criteria, the real prevalence of resistant hypertension in a clinical setting is unknown. OBJECTIVE: We investigated the prevalence of true resistant hypertension in an outpatient hypertension clinic. METHODS: True resistant hypertension was diagnosed when white coat phenomenon, lack of compliance and secondary ...
Thoroddsen Asta - - 2012
Scand J Caring Sci; 2012 Accuracy, completeness and comprehensiveness of information on pressure ulcers recorded in the patient record Aim:  To describe the accuracy, completeness and comprehensiveness of information on pressure ulcers documented in patient records. Design and setting:  A cross-sectional descriptive study performed in 29 wards at a university ...
Fici Francesco - - 2012
Essential hypertension is characterized by a left ventricular dysfunction. However, the majority of the studies performed so far investigated patients under drug treatment and/or with concomitant diseases, such as obesity, diabetes, metabolic syndrome or coronary heart disease, which per se may affect diastolic function independently on the blood pressure elevation. ...
Wang Ke - - 2012
We investigated surgical outcomes of haematoma evacuation in patients with hypertensive putaminal haemorrhage, with emphasis on the development of postoperative refractory intracranial hypertension. Twenty-two consecutive patients with hypertensive putaminal haemorrhage underwent microsurgical clot removal without decompressive craniectomy. Medical histories, radiographic findings, and surgical notes were reviewed. Twenty patients survived to ...
Carron Michele - - 2012
BACKGROUND:: The stress responses from tracheal intubation are potentially dangerous in patients with higher cardiovascular risk, such as obese patients. The primary outcome objective of this study was to test whether, in comparison with the endotracheal tube (ETT), the Proseal™ Laryngeal Mask Airway (PLMA™) (Laryngeal Mask Airway Company, Jersey, United ...
Leonardis L - - 2012
BACKGROUND: Various breathing abnormalities (Neurology 2009; 73: 1218) have been proposed as indicators for the introduction of non-invasive positive-pressure ventilation (NIV) in patients with amyotrophic lateral sclerosis (ALS). We were interested in the usefulness of symptoms of respiratory insufficiency and abnormal results of daytime arterial gas analyses (AGA) as predictors ...
Skau Maren - - 2012
BACKGROUND: Idiopathic intracranial hypertension (IIH) is a condition of raised intracranial pressure (ICP) in the absence of space-occupying lesions or other known etiology. It primarily affects young obese females, and potentially causes permanent visual loss due to papilledema and secondary optic atrophy. The aim of this study was to evaluate ...
Ortiz Martín Ruiz - - 2012
J Clin Hypertens (Greenwich). 2012;00:00-00 ©2012 Wiley Periodicals, Inc. The authors' aim was to investigate the prognostic value of first-visit systolic and diastolic blood pressure (SBP/DBP) in hypertensive patients with stable coronary artery disease (sCAD) in conditions of contemporary daily clinical practice. From February 1, 2000, to January 31, 2004, ...
Biner Simon - - 2012
AIMS: To evaluate the haemodynamic effect of acute procedural success (APS) after MitraClip therapy in patients with haemodynamic decompensation. METHODS AND RESULTS: Of 107 patients, 79 achieved APS after MitraClip implantation. The increase in cardiac index (CI) was primarily detected in patients with a low baseline CI (2.0 ± 0.5 ...
Stav Kobi - - 2012
PURPOSE: We determined whether patients with bladder pain syndrome who have typical interstitial cystitis endoscopic findings, including glomerulations and/or Hunner ulcer, have a distinct autonomic response during bladder hydrodistention. MATERIALS AND METHODS: Included in the study were 50 consecutive patients (40 females and 10 males) who met International Society for ...
Gkaliagkousi Eugenia - - 2012
Increased expression and activity of metalloproteinases have been implicated in the pathophysiology of vascular remodeling and in the growth of atherosclerotic lesions. We aimed at determining the levels of MMP-2, MMP-9, their specific inhibitors TIMP-2 and TIMP-1, and the inflammatory cytokines IL-6 and TNF-α, which are related to the stimulation ...
Bulur Serkan - - 2012
Mean platelet volume (MPV) has been recognized as an independent risk factor of hypertension. Hypertensive end-organ damage worsens the prognosis in hypertensive patients. We aimed to investigate the relationship between MPV levels and subclinical end-organ damage in hypertensive patients. One hundred and sixteen hypertensive patients (81 women, 35 men, with ...
Omboni Stefano - - 2012
OBJECTIVE:: To assess the antihypertensive efficacy of olmesartan medoxomil and ramipril on 24-h ambulatory blood pressure (ABP) in elderly hypertensive patients by pooled data analysis of two studies with identical designs (one Italian, one European). METHODS:: After a 2-week placebo wash-out 1453 elderly hypertensive patients (65-89 years; sitting office DBP ...
King-Schultz Leslie - - 2012
J Clin Hypertens (Greenwich). 2012; 14:396-400. ©2012 Wiley Periodicals, Inc. Shorter-interval (6-hour) ambulatory blood pressure monitoring (ABPM) has been shown to correlate well with 24-hour ABPM in adults, but this has not been studied in children. The authors selected 131 patients aged 9 to 18 who underwent 24-ABPM from 2000-2008. ...
Takenaka Tsuneo - - 2012
Diabetic nephropathy (DN) is a leading disease that requires renal replacement therapy. The progression of renal dysfunction in DN is faster than the other renal diseases. While antihypertensive therapy reduces albuminuria, a good indicator for the progression, hypertension in DN is treatment resistant. Among patients with DN who took angiotensin ...
Keller Geoffray - - 2012
To assess if combining central venous pressure (CVP) and/or pulmonary capillary wedge pressure (PCWP) information with arterial pulse pressure variation can increase the ability to predict fluid responsiveness in patients under general anesthesia. This study is a retrospective analysis of patients scheduled for coronary artery bypass surgery and monitored with ...
Sarzani Riccardo - - 2012
BackgroundThe aim of this study was to evaluate whether body mass index (BMI) is independently correlated with plasma aldosterone concentration (PAC) in treated essential hypertensive patients, and whether the relationship between BMI and high blood pressure (BP) can be partially mediated by PAC despite renin-angiotensin-aldosterone system blockade.MethodsThis study used a ...
Kanaoka Tomohiko - - 2012
J Clin Hypertens (Greenwich). 2012;00:000-000. ©2012 Wiley Periodicals, Inc. Aliskiren is a direct renin inhibitor that exerts its effect at the rate-limiting step of the renin-angiotensin system. This study was performed to examine the beneficial effects of aliskiren-based antihypertensive therapy on the ambulatory blood pressure (BP) profile, central hemodybamics, and ...
He Quan-Ying - - 2012
The nocturnal nondipping and elevated morning blood pressure (BP) in patients with obstructive sleep apnea syndrome (OSAS) have not yet been well investigated in Chinese patients. This study aimed to describe the BP profile, and to elucidate the relationships between daytime BP and nighttime BP, and between evening BP and ...
Wen Jianmin - - 2012
BACKGROUND: Hallux valgus (HV) is one of the most common deformities in podiatric and orthopedic practice. Plantar pressure technology has been widely used in studying the pressure distribution in HV patients for better assessment to plan interventions. However, previous studies produced an array of controversial findings and most of them ...
Teo I - - 2012
Hair extensions - an intraoperative risk for occipital pressure ulceration Use of hair extensions has surged in popularity in the last decade. Hair extensions are usually used for cosmetic reasons, although they also offer a noninvasive and easily available alternative for alopecia patients. Here, we describe an unusual risk of ...
Jiao Yuan - - 2012
To investigate the morning blood pressure surge (MBPS) in Chinese patients with mild to moderate essential hypertension treated with long-term administration of olmesartan, an angiotensin II receptor antagonist according to ambulatory blood pressure monitoring (ABPM). In a multi-center, prospective study, we investigated the long-term efficacy of olmesartan by ABPM in ...
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