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Xiao Y - - 2013
Cough and throat clearing might be difficult to differentiate when trying to detect them acoustically or manometrically. The aim of this study was to assess the accuracy of acoustic monitoring for detecting cough and throat clearing, and to also determine whether these two symptoms present with different manometric profiles on ...
Chen Chien-Lin - - 2013
INTRODUCTION: Patients with non-obstructive dysphagia (NOD) report symptoms of impaired esophageal bolus transit without evidence of bolus stasis. In such patients manometric investigation may diagnose esophageal motility disorders however many have normal motor patterns. We hypothesised that patients with NOD would demonstrate evidence of high flow-resistance during bolus passage which ...
Chen Chien-Lin - - 2013
BACKGROUND: Secondary peristalsis contributes to clearance of retained refluxate or material from the esophagus. AIM: The goal of our study was to investigate the effects of hydrochloric acid (HCl) on physiological characteristics of esophageal secondary peristalsis in healthy adults. METHODS: After recording esophageal motility baseline for primary peristalsis, secondary peristalsis ...
Ashkenazi Eyal - - 2013
Portal hypertension is the leading cause of morbidity and mortality in liver cirrhosis. Complications of portal hypertension in cirrhotic patients include esophageal and gastric varices, portal hypertensive gastropathy, ascites, hepatorenal syndrome, hepatopulmonary syndrome and portopulmonary hypertension. The hepatic venous pressure gradient should be at least 10 mmHg for esophageal varices ...
Gyawali C P - - 2013
Esophageal motor function is highly coordinated between central and enteric nervous systems and the esophageal musculature, which consists of proximal skeletal and distal smooth muscle in three functional regions, the upper and lower esophageal sphincters, and the esophageal body. While upper endoscopy is useful in evaluating for structural disorders of ...
Roman Sabine S Department of Digestive Physiology, Edouard Herriot Hospital, Pavillon H, 5 place d’Arsonval, 69437 Lyon, CEDEX 03, France. - - 2013
Although successful treatment of achalasia depends on alleviating the obstruction at the esophagogastric junction, the postintervention contractile and pressurization pattern may also play a role in outcome. To determine whether myotomy that alleviates the esophagogastric junction outflow obstruction in achalasia might improve peristalsis. Retrospective study from August 1, 2004, through ...
Carlson Dustin A DA Department of Medicine, Feinberg School of Medicine, Northwestern University, Suite 3-150, 251 East Huron, Chicago, IL 60611, - - 2013
Although conventional manometry set the basis for the diagnosis of esophageal motility disorders, the large axial spacing between recording sites leaves large portions of the esophagus unevaluated and vulnerable to movement artifact. However, continuous spatiotemporal representations of pressure through the esophagus recorded with high-resolution manometry offers greater detail and improved ...
Regan J J School of Clinical Medicine, Trinity College Dublin, Dublin, Ireland. - - 2013
This paper aims to measure upper esophageal sphincter (UES) distensibility and extent and duration of UES opening during swallowing in healthy subjects using EndoFLIP(®). Fourteen healthy subjects (20-50 years) were recruited. An EndoFLIP(®) probe was passed trans-orally and the probe balloon was positioned across the UES. Two 20-mL ramp distensions ...
Nguyen N Q - - 2012
Background  Automated integrated analysis of impedance and pressure signals has been reported to identify patients at risk of developing dysphagia post fundoplication. This study aimed to investigate this analysis in the evaluation of patients with non-obstructive dysphagia (NOD) and normal manometry (NOD/NM). Methods  Combined impedance-manometry was performed in 42 patients ...
Kessing B F - - 2012
Background  Esophageal impedance monitoring has made it possible to distinguish two types of belches, designated gastric and supragastric. We aimed to compare the esophageal pressure characteristics during supragastric belches and gastric belches using combined high-resolution manometry and impedance monitoring. Methods  We included 10 patients with severe and frequent belching. Combined ...
Lee Tae Hee - - 2012
To evaluate the effects of the phosphodiesterase type 5 (PDE5) inhibitor vardenafil on esophageal function, including bolus transit, using multichannel intraluminal impedance and esophageal manometry (MII-EM). Sixteen healthy volunteers (15 men) underwent an MII-EM study including 10 liquid swallows and 10 viscous swallows in a seated position after fasting. Then, ...
Turan Alparslan - - 2012
Many anesthetics reduce lower esophageal sphincter pressure (LESP) and consequently the gastro-esophageal pressure gradient (GEPG); thus they may promote gastro-esophageal reflux and contribute to aspiration pneumonia. Our goals were to evaluate the association between LESP and 2 measures of sedation: bispectral index (BIS) and the responsiveness component of the Observer's ...
Carvalho de Miranda Chaves Renata - - 2012
Inspiratory muscle training (IMT) has been shown to increase diaphragm thickness. We evaluated the effect of IMT on mid-respiratory pressure (MRP) in patients with gastroesophageal reflux disease (GERD) and hypotensive lower esophageal sphincter (LES), and compared the results with a sham group. Twenty consecutive patients (progressive loading group) and 9 ...
Morgenstern C C CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Institute for Bioengineering of Catalonia and Deptartment ESAII, Universitat Politècnica de Catalunya (UPC), Barcelona, Spain. - - 2013
The identification of obstructive and central hypopneas is considered challenging in clinical practice. Presently, obstructive and central hypopneas are usually not differentiated or scores lack reliability due to the technical limitations of standard polysomnography. Esophageal pressure measurement is the gold-standard for identifying these events but its invasiveness deters its usage ...
Omari T - - 2012
Background  Pharyngeal propulsion, strength of peristalsis and esophago-gastric junction (EJG) resistance are determinants of esophageal bolus transport. This study used pressure-impedance methods to correlate pharyngo-esophageal function with the esophageal bolus trajectory pathway and pressures generated during bolus transport. Methods  Pharyngo-esophageal pressure-impedance measurements were performed in 20 healthy adult controls. Pharyngeal ...
Wilshire Candice L - - 2012
BACKGROUND: Historically, risk assessment for postfundoplication dysphagia has been focused on esophageal body motility, which has proven to be an unreliable prediction tool. Our aim was to determine factors responsible for persistent postoperative dysphagia. METHODS: Fourteen postfundoplication patients with primary dysphagia were selected for focused study. Twenty-five asymptomatic post-Nissen patients ...
Xiao Yinglian - - 2012
There are currently no criteria for ineffective esophageal motility (IEM) and ineffective swallow (IES) in esophageal pressure topography (EPT). Our aims were to use high-resolution manometry metrics to define IEM within the Chicago Classification and to determine the distal contractile integral (DCI) threshold for IES. The EPT of 150 patients ...
Roberts Justin C - - 2012
With mortality rates approaching 40%, septic shock is one of the most common causes of death on intensive care units. Vasodilatation, myocardial depression and fluid loss as a result of increased capillary permeability result in hypotension and impaired organ perfusion. Multiple organ failure as a consequence of organ hypo-perfusion results ...
Shantsila Alena - - 2012
: To investigate the impact of pulse pressure at presentation on the primary outcome (death or dialysis) in patients with malignant phase hypertension (MPH). : Three hundred and sixty-five patients [overall mean (SD) age 48 (13) years; 66% male; 63% white European; 23% African-Caribbean, 14% south Asian] from the West ...
Arbour Richard B - - 2012
Brain death is characterised by a flaccid, areflexic neurological examination; fixed, dilated and midpoint pupils and total absence of intrinsic respiratory drive. A non-reversible clinical state or brain lesion must also be identified. Integral to brain death diagnosis is loss of respiratory drive. Following terminal brainstem herniation, a cardiovascular hyperdynamic ...
Tsuboi Kazuto - - 2012
Three lower esophageal sphincter (LES) characteristics associated with gastro-esophageal reflux disease (GERD) are, LES pressure = 6 mmHg, abdominal length (AL) <1 cm and overall length (OL) <2 cm. The objective of this study was to validate this relationship and evaluate the extent of impact various LES characteristics have on ...
Allen Bradley S - - 2012
Neurologic injury after sudden death is likely due to a reperfusion injury following prolonged brain ischaemia, and remains problematic, especially if the cardiac arrest is unwitnessed. This study applies a newly developed isolated model of global brain ischaemia (simulating unwitnessed sudden death) for 30 min to determine if controlled reperfusion ...
Inoue Ryusuke - - 2012
BackgroundTo clarify whether the double product (DP) (product of systolic blood pressure (SBP) and pulse rate (PR)) at rest based on home blood pressure (HBP) measurement has prognostic value for mortality.MethodsHBP data of 2,583 participants from a Japanese general population (40% men) ≥35 years of age (mean, 59 years) without ...
Shah Buddha R - - 2012
The dynamics of amyloid fibrils, including their formation and dissociation, could be of vital importance in life. We studied the kinetics of dissociation of the amyloid fibrils from wild-type hen lysozyme at 25°C in vitro as a function of pressure using Trp fluorescence as a probe. Upon 100-fold dilution of ...
Li Faith C H - - 2012
Whereas sudden death, most often associated with cardiovascular collapse, occurs in abusers of the psychostimulant methamphetamine (METH), the underlying mechanism is much less understood. The demonstration that successful resuscitation of an arrested heart depends on maintained functionality of the rostral ventrolateral medulla (RVLM), which is responsible for the maintenance of ...
Rees Karen K Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, - - 2012
This is the protocol for a review and there is no abstract. The objectives are as follows: The primary objective is to determine the effectiveness of selenium only supplementation for the primary prevention of CVD. We will also determine potential adverse effects of selenium only supplementation on major CVD risk ...
Ewart Craig K CK Department of Psychology, Syracuse University, and Center for Health and Behavior, Syracuse University, Syracuse, NY 13244, - - 2011
Three motivational profiles have been associated with recurring psychological stress in low-income youth and young adults: Striving to control others (agonistic striving), striving to control the self (transcendence striving), and not asserting control (dissipated striving). Agonistic striving has been associated with elevated ambulatory blood pressure during daily activities. Three studies ...
Patterson M F - - 2011
A cocktail of Listeria monocytogenes strains was inoculated into cooked chicken (∼2.2 × 10(3) CFU g(-1)) which was then pressure-treated (600 MPa/2 min/20 °C) and stored for up to 105 days at 8 °C. In addition, sodium lactate (2% w/w) or a pressure-resistant Weissella viridescens strain, known to have antilisterial activity, were added to the meat prior to ...
Eme John - - 2011
Hypoxia is a naturally occurring environmental challenge for embryonic reptiles, and this is the first study to investigate the impact of chronic hypoxia on the in ovo development of autonomic cardiovascular regulation and circulating catecholamine levels in a reptile. We measured heart rate (f(H)) and chorioallantoic arterial blood pressure (MAP) ...
Monza A - - 2011
In this work we investigate the magnetic and structural properties of bulk Fe and Fe nanoparticles under pressure with x-ray absorption and emission spectroscopies providing answers to two fundamental questions: (a) the chicken-or-egg problem for the magnetic and structural transitions and (b) magnetism in the high pressure hcp phase. The two transitions, ...
Rayner B - - 2011
Dopamine via G-protein-coupled receptor kinase 4 (GRK-4) regulates sodium (Na) balance in the proximal tubule of the kidney. Single-nucleotide polymorphisms of GRK-4 have been linked to impaired natriuresis and salt-sensitive hypertension. The purpose of this report was to determine the effect of GRK-4 gene polymorphisms on the blood pressure (BP) ...
Ram C Venkata - - 2011
The safety and efficacy of an amlodipine/olmesartan medoxomil (OM)-based titration regimen was assessed in patients with type 2 diabetes mellitus and hypertension. After a 2- to 3-week placebo run-in period, 207 patients received amlodipine 5 mg and were uptitrated to amlodipine/OM 5/20, 5/40, and 10/40 mg and then amlodipine/OM 10/40 ...
Furusawa Erika A - - 2011
BackgroundTo evaluate the effect of the environment and the observer on the measurement of blood pressure (BP) as well as to compare home BP (HBP) and ambulatory BP (ABP) measurements in the diagnosis of white coat hypertension (WCH) and masked hypertension (MH) in children and adolescents with hypertension (HT).MethodsBP of ...
Schutte Rudolph - - 2011
Recent evidence suggests that low-grade urinary albumin excretion is a marker of early general attenuation of vascular function, but studies are limited to Caucasian population groups. We compared low-grade urinary albumin excretion (<3.5 mg mmol(-1) or 30 μg mg(-1)) between non-diabetic African (aged, 41.7 years; n=70) and Caucasian (aged, 44.6 years; n=91) men and ...
Sabater-Hernández Daniel - - 2011
BackgroundThere is little information regarding the community pharmacy blood pressure (CPBP) measurement method and their differences with home (HBP) or ambulatory BP (ABP). The aim of this study was to measure such differences and their variation over successive visits.MethodCross-sectional study carried out in eight pharmacies in Gran Canaria (Spain). The ...
Israel Sarah - - 2011
BackgroundMorning blood pressure surge (MS) is accepted to increase cardiovascular risk, but it is not clear how it should be defined. Because dipping on 24-h ambulatory blood pressure monitoring (ABPM) associates with improved outcome we hypothesized that MS will not predict mortality independent of dipping.MethodsWe investigated a cohort of 2,627 ...
García-Ortiz Luis - - 2011
OBJECTIVES: To analyze the relationship between office and ambulatory heart rate, and its variability, and arterial stiffness in patients with primary arterial hypertension. METHODS: A cross-sectional study was conducted in a primary care setting, with the inclusion of 356 hypertensive patients aged 30-80 years. Office and ambulatory blood pressure, heart ...
Rahbari-Oskoui Frederic F FF Renal Division, Department of Medicine, Emory University School of Medicine Atlanta, Georgia 30322, USA. - - 2011
Nondipping, defined as a less than 10% decline in Night:Day (N:D) ratio of blood pressure using 24 h ambulatory blood pressure monitoring, is associated with poor cardiovascular outcomes. However, its reproducibility has been questioned in autosomal dominant polycystic kidney disease. Twenty-five of 29 recruited hypertensive or prehypertensive patients with autosomal ...
de la Sierra Alejandro - - 2011
We aimed to estimate the prevalence of resistant hypertension through both office and ambulatory blood pressure monitoring in a large cohort of treated hypertensive patients from the Spanish Ambulatory Blood Pressure Monitoring Registry. In addition, we also compared clinical features of patients with true or white-coat-resistant hypertension. In December 2009, ...
Andreadis Emmanuel A - - 2011
BackgroundTo determine whether automated office blood pressure (AOBP) readings are associated with left ventricular mass (LVM) index as closely as those of 24-h ambulatory blood pressure (ABP) and also to confirm that the values of the two methods are comparable in the appraisal of blood pressure in a European population ...
O'brien Eoin - - 2011
If ambulatory blood pressure measurement is not possible because the upper-arm circumference is so great that even the largest cuff provided with the monitor will not encircle the arm, satisfactory measurements can be obtained by applying a cuff to the forearm.
van der Wel Mark C - - 2011
Current office blood pressure measurement (OBPM) is often not executed according to guidelines and cannot prevent the white-coat effect. Serial, automated, oscillometric OBPM has the potential to overcome both these problems. We therefore developed a 30-minute OBPM method that we compared with daytime ambulatory blood pressure. Patients referred to a ...
Huang Chi-Ming - - 2011
Central systolic (SBP-C) and/or pulse pressure (PP-C) better predicts cardiovascular events than does peripheral blood pressure. The present study compared the prognostic significance of office central blood pressure with multiple measurements of out-of-office ambulatory peripheral blood pressure, with reference to office peripheral systolic (SBP-B) or pulse pressure (PP-B). In a ...
Angeli Fabio - - 2011
BackgroundElevated neutrophil count, a marker of systemic inflammation, has been suggested as a prognostic marker of cardiovascular disease in postmenopausal women with hypertension. We tested the hypothesis that an association exists between elevated neutrophil count and increased arterial stiffness, as reflected by a wide pulse pressure (PP), in this population ...
Messerli Franz H - - 2011
The purpose of this study was to evaluate the antihypertensive efficacy of hydrochlorothiazide (HCTZ) by ambulatory blood pressure (BP) monitoring. HCTZ is the most commonly prescribed antihypertensive drug worldwide. More than 97% of all HCTZ prescriptions are for 12.5 to 25 mg per day. The antihypertensive efficacy of HCTZ by ...
Sinha Rajiv - - 2011
Recently there have been great advances in the use of ambulatory blood pressure monitoring (ABPM) in children. A major boost has been the publication of normative data for blood pressure in children. ABPM has been able to detect significant differences in blood pressure in many disease states including chronic renal ...
Enström Inger Elisabet - - 2011
To compare ambulatory blood pressure recorded during a work day with a leisure day regarding masked hypertension. A randomized crossover study in middle-aged normotensives. Thirty-seven untreated middle-aged normotensives (17 women), who had repeated office blood pressure less than 140/90 mmHg. Individual difference of masked hypertension between a work day and ...
Coll de Tuero Gabriel - - 2011
Self-blood pressure (BP) measurement (SBPM) and ambulatory BP measurement (ABPM) are suitable for the isolated clinical hypertension (ICH) or 'white-coat' hypertension diagnosis. However, patients with ICH have a different cardiovascular risk according to the measurement technique used for the diagnosis. To describe baseline cardiovascular risk of patients with hypertension and ...
Neglia Danilo - - 2011
Patients and animal models of arterial hypertension are characterized by structural and functional abnormalities of the coronary microcirculation. Using a translational approach, we ascertained whether antihypertensive treatment can reverse microvascular remodelling and improve myocardial perfusion. In 20 hypertensive patients with left ventricular hypertrophy, blood pressure, left ventricular mass index and ...
Sinha Manish D - - 2011
AimTo analyse blood pressure characteristics during 24-hour ambulatory blood pressure monitoring in children and to assess factors that influence its success over 24 hours and during patient-recorded awake (DAY) and sleep (NIGHT) periods. METHODS: A total of 169 consecutive ambulatory blood pressure monitoring studies were conducted in 154 patients over ...
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