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Results 701 - 750 of 1364
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Rizzo V - - 1996
In a consecutive series of 62 hypertensive elderly subjects, the authors studied the relation of blood pressure circadian variations with echocardiographic parameters of left ventricular (LV) hypertrophy. All the subjects were submitted to an ambulatory blood pressure monitoring (ABPM) and to B- and M-mode echocardiography. In the elderly hypertensive group, ...
Bhatt DL - - 1996
OBJECTIVES: To assess the impact of blood pressure level and variability on left ventricular geometry. METHODS: Twenty-four-hour ambulatory systolic blood pressure (SBP) and diastolic blood pressure (DBP) were related to echocardiographic left ventricular geometry in 76 normotensive and 245 hypertensive adults. RESULTS: The differences in SBP and DBP between hypertensive ...
Muse-Danielov M - - 1996
In 41 patients suffering from hypertension blood pressure values obtained in routine examinations in an outpatient clinic were analysed by correlating the highest values of blood pressure measured using the 24-hour monitoring model developed by Holter and those obtained in exertion tests developed by Bruce. The correlation coefficients indicated poor ...
Mancia G - - 1996
PREDICTIVE VALUE OF 24-H AMBULATORY BLOOD PRESSURE MONITORING: Average 24-h blood pressure values are more closely related to the target-organ damage of hypertension than are clinic blood pressure readings. Preliminary evidence from longitudinal studies suggests that ambulatory blood pressure is also superior to isolated clinic readings in the prognostic evaluation ...
Arita M - - 1996
To evaluate mechanisms responsible for differences between patients showing a nocturnal fall in blood pressure ("dippers") and those showing no such fall in blood pressure ("nondippers"), we performed 24-hour (h) ambulatory blood pressure monitoring in 25 patients with untreated essential hypertension who were 37-49 years of age (16 men and ...
Imai Y - - 1996
We estimated the prevalence of hypertension and evaluated the degree of blood pressure control on the basis of ambulatory blood pressure monitoring in patients receiving antihypertensive medication. A total of 969 adults (mean age +/- SD, 59.3 +/- 12.1 years old range: 20-79 yr) among 1,575 eligible persons (65.1%) recruited ...
Straka R J - - 1996
Recognition of the existence of circadian variation in exacerbation of cardiovascular disease may have relevance to clinical use of cardioactive agents. Physiologic rational for the chronobiology of cardiac disease exists and can provide a basis on which to examine the efficacy of agents to manage cardiac disease. The use of ...
Beltman F W - - 1996
OBJECTIVE: To determine whether ambulatory blood pressure eight weeks after withdrawal of antihypertensive medication is a more sensitive measure than seated blood pressure to predict blood pressure in the long term. DESIGN: Patients with previously untreated diastolic hypertension were treated with antihypertensive drugs for one year; these were withdrawn in ...
Bieniaszewski L - - 1996
Ambulatory blood pressure monitoring is increasingly used in clinical trials. The preliminary threshold values proposed for diagnosing hypertension and adjusting treatment based on ambulatory monitoring cannot yet be widely recommended because they have not been validated in prospective studies. The trough-to-peak or surface ratios may be useful instruments for assessing ...
Parati G - - 1996
The availability of ambulatory intraarterial blood pressure monitoring techniques offers a deeper insight into the features of blood pressure variability over 24 hours and allows better understanding of the mechanisms responsible for the continuous and marked blood pressure changes that occur throughout the day and at night. Among these mechanisms, ...
Marx M A - - 1996
Blood pressure normally follows a characteristic pattern throughout the 24 h cycle with daytime pressures higher than nighttime pressures. Patients lacking a nocturnal decrease in pressure have a higher incidence of end organ damage. This investigation was designed to characterize the diurnal pattern of blood pressure and to evaluate blood ...
Korpinen L - - 1996
This investigation studied the effects of 50-Hz electric and magnetic fields on the pulse rate and blood pressure in humans. Electrocardiograms (ECG) and the blood pressure of 41 male volunteers were recorded using ambulatory methods. Twenty-six subjects were measured in and outside real fields and 15 subjects in and outside ...
Hietanen E - - 1996
The aim of the present study has been to study the reproducibility, validity and normal values of ambulatory blood pressure measurement in a healthy Finnish cohort. The reproducibility of ambulatory blood pressure monitoring was examined in healthy volunteers and normal values were determined in a Finnish cohort of males and ...
Chamontin B - - 1996
OBJECTIVE: To determine the links between circadian blood pressure rhythm and metabolic profile in overweight essential hypertensive men with an elevated waist: hip ratio (> 0.95). METHODS: Ambulatory blood pressure monitoring (ABPM) was performed in 53 patients (using a SpaceLabs 90207 device) after withdrawal of antihypertensive medication. All of the ...
Cesana G - - 1996
OBJECTIVES: The purpose of this cross-sectional study was to examine the associations between categories of perceived job strain and blood pressure, measured by clinical and ambulatory devices on a population-based sample of employed men in northern Italy. METHODS: The study included 527 employed normotensive or mild hypertensive nonmedicated men enrolled ...
Mansoor GA - - 1996
OBJECTIVE: To study the effects of actigraphic, diary and fixed-time methods of analysis on ambulatory blood pressure, the day (awake)-night (asleep) difference and early morning blood pressure. METHODS: We analyzed 50 ambulatory blood pressure studies of patients who also underwent actigraphic activity studies. We divided each study into awake and ...
Høegholm A - - 1996
OBJECTIVE: To investigate the interrelations between blood pressure variables and treatment effects in white-coat and established hypertensive patients. DESIGN: A substudy on data from a randomized clinical trial on two dihydropyridine calcium antagonists, in which treatment intensity relied on office blood pressure, but with ambulatory blood pressure recordings performed before ...
Kriesand T - - 1996
Blood pressure measurements made in the physician's office have been the standard for diagnosing hypertension and determining the efficacy of antihypertensive drug therapy. However, these measurements do not necessarily reflect a patient's usual blood pressures in other circumstances, such as at work or in the home. Accurate blood pressure measurements ...
Heude E - - 1996
1. The aim of the study was to assess the effect of ambulatory monitoring of blood pressure on sleep and on blood pressure in middle-aged patients. 2. Nine consecutive patients (seven men, two women; mean age 57 years) complaining of snoring and various degrees of excessive daytime somnolence were studied. ...
Asmar R - - 1996
This session was devoted to the application of ambulatory blood pressure monitoring (ABPM) to evaluate the therapeutic efficacy of antihypertensive treatment. Several aspects of this large field have been discussed, but others, no less important, need to be treated and clarified in the future.
Herpin D - - 1996
The main advantages of ambulatory blood pressure monitoring (ABPM) over clinic blood pressure measurements are the following: the lack of an alarm reaction and of observer bias; repeated readings during 24 h in the customary environment of the patient, instead of a single measurement in the doctor's office; superior reproducibility, ...
Lingens N - - 1996
Ambulatory blood pressure monitoring during 24 hours was applied in 34 pediatric patients aged 6.3 to 24.3 (median 14.0) years who had been transplanted 0.3 to 8.4 years previously. The mean arterial blood pressure levels measured during the daytime and at night correlated positively (r = 0.70), but 14 of ...
Asmar R - - 1996
OBJECTIVE: To determine whether non-invasive ambulatory blood pressure is more reproducible and less affected by the placebo treatment than are clinic blood pressure measurements. METHOD: Thirty-four essential hypertensive outpatients were randomly allocated after a 4-week preselection period in two groups in a cross-over study design. One group received placebo for ...
Asmar R - - 1996
The session devoted to the usefulness of non-invasive ambulatory blood pressure monitoring (ABPM) in the evaluation of antihypertensive therapy allowed us to discuss a number of important issues. ABPM emerged as a widely accepted technique to measure blood pressure in clinical trials. Actually, it was generally considered to provide more ...
Parati G - - 1996
Clinic blood pressure readings are less reproducible than 24 h and daytime average ambulatory blood pressures. This may depend on (1) the continuous and spontaneous variability which characterizes daily life blood pressure, (2) the well-known 'white-coat' effect and (3) other methodological problems affecting traditional sphygmomanometric readings, such as the observer's ...
Andréjak MJ - - 1996
Ambulatory blood pressure monitoring (ABPM) is now widely used for the assessment of antihypertensive agents. This procedure may be used in phase II studies in dose-ranging evaluations. Indeed, ABPM provides data more appropriate for determining the dose-response relationship than are those from conventional blood pressure measurement. For each dose, it ...
Waeber B - - 1996
OBJECTIVE: To analyse a randomized study undertaken to compare the antihypertensive efficacy of dihydropyridine calcium antagonists in patients with essential hypertension. METHOD: Blood pressure was measured both conventionally by a doctor and by non-invasive ambulatory monitoring. RESULTS: During amlodipine therapy (5 mg once a day for 4 weeks, n = ...
Clement DL - - 1996
Ambulatory blood pressure monitoring (ABPM) has become one of the major clinical tools used to investigate the hypertensive patient. The technique is still cumbersome and embarassing for the patient, both during daily activities and during nightly rest. Nonetheless, the information to be obtained can be very useful for diagnosis and ...
Perloff D - - 1996
Monitoring the blood pressure of individuals throughout the day and night has p;rovided information concerning the variability of blood pressure, the diurnal fluctuation of blood pressure levels, and the often exaggerated response of some individuals to the medical environment, the 'white-coat' effect. The average of multiple pressures obtained during the ...
Gosse P - - 1996
Four points, I feel, have dominated the session devoted to the methods of measurement; First, we all seem to be convinced that ambulatory measurement of blood pressure shows great promise, not only in clinical trials of drugs but also in routine practice. Further development of the technique will almost certainly ...
Kawasaki T - - 1996
OBJECTIVE: To investigate the effects of chronic smoking on the 24 h blood pressure and heart rate pattern in normotensive subjects. METHODS: Twenty-five smokers and 25 age-, weight- and height-matched non-smokers, who were all clinically healthy young men, gave their informed consent to undergo non-invasive, automated, ambulatory blood pressure monitoring ...
White WB - - 1996
By reducing measurement error associated with clinic (or casual) blood pressure, ambulatory blood pressure measurement (ABPM) potentially enhances the precision of blood pressure estimation. Enhanced precision leads to lower sample size requirements or increased statistical power, or both, in clinical trials. Thus, by virtue of its increased numbers of measurements ...
Vaïsse B - - 1996
Ambulatory blood pressure monitoring (ABPM) is now very useful for assessing the blood pressure response to antihypertensive drugs. It gives accurate information on blood pressure profiles and provides more detailed information on first-dose effects, dose-response relationships, and the direction of action of antihypertensive treatment. However, ABPM studies will also allow ...
O'Brien E - - 1996
INTRODUCTION: When the technique of blood pressure measurement was introduced into clinical medicine during the early years of this century, the importance of accuracy and the limitations of the technique were well recognized [1]. However, the standards called for by the clinicians and scientists who introduced the technique were relaxed ...
Imai Y - - 1996
OBJECTIVE: To investigate the risks of high and low blood pressure levels determined by ambulatory blood pressure monitoring and home blood pressure measurements. METHODS: A long-term prospective study of all-cause mortality and cardiovascular mortality has been conducted in Ohasama, Japan since 1987. RESULTS: The Cox proportional hazards model after adjusting ...
Fioravanti M - - 1996
The study of the relationship between hypertension and cognitive decline is characterized by various difficulties of realization and, as a consequence, by incongruent results. One of the reasons for these difficulties may be explained by the occasional method of measurement of blood pressure (once a day). This study presents the ...
Staessen JA - - 1996
Ambulatory blood pressure monitoring is increasingly being used in clinical trials. Trials with ambulatory monitoring, just like clinical experiments based on conventional sphygmomanometry, need to be controlled properly, because ambulatory blood pressure measurements are not completely devoid of placebo-like effects. The trough: peak ratio might be a useful instrument for ...
Chamontin B - - 1996
Ambulatory blood pressure monitoring (ABPM) provides reproducible measurements over 24 h, avoiding the alerting reaction. However, the reproducibility of mean hourly ambulatory values is poorer by far than the whole day average. In phases II and III clinical triams ABPM seems to evaluate the time-course of the antihypertensive effect and ...
Meredith PA - - 1996
The trough: peak ratio for the response to an antihypertensive drug is a clinically meaningful parameter only when the index has been derived and calculated from an appropriately designed and conducted study. The original draft guidelines made no recommendations concerning the most appropriate methodology, hence trough: peak values have been ...
de Graeff - - 1996
So far, the contribution of clinical studies using ambulatory blood pressure monitoring in the registration of a new antihypertensive agent for marketing authorization purposes has been limited. However, pre-registration studies can be particularly useful, especially to study dose and dose interval in relation to peak: trough ratio during phase II ...
Mallion JM - - 1996
OBJECTIVE: To establish the acceptability and tolerance of ambulatory blood pressure monitoring (ABPM). METHODS: A two-part questionnaire was completed by the doctor; one part before ABPM and the second after the recording. The pre-recording data concern the demographic data of the patient: previous illness, symptoms, reaction of the patient, anthropometric ...
Mancia G - - 1996
A number of cross sectional studies have shown that both the 24-hour average blood pressure value and the degree of 24-hour blood pressure variability bear a significant relation with the end organ damage of hypertension. Although longitudinal evidence of the clinical relevance of 24-hour ambulatory blood pressure monitoring data are ...
Fagard R - - 1996
Subjects with elevated conventional clinic or office blood pressure (CBP) may have normal ambulatory blood pressure (ABP). The purpose of this review is to summarize studies in which ABP was monitored while the initiation or intensification of antihypertensive therapy was guided by CBP. These studies show that ABP does not ...
Verdecchia P - - 1996
OBJECTIVE: To assess the spontaneous changes in clinic blood pressure, ambulatory blood pressure (ABP) and left ventricular structure in untreated subjects with white-coat hypertension (WCH). DESIGN: A prospective observational study. PATIENTS AND METHODS: In 83 untreated subjects with WCH, 24 h non-invasive ABP monitoring and echocardiographic studies of the left ...
Suzuki M - - 1996
Obstructive sleep apnea syndrome (OSAS) has been associated with a higher than normal cardiovascular morbidity and mortality. Some OSAS patients lack the sleep-related, nocturnal decrease, or "dip," in blood pressure which is seen in normal individuals. These subjects, called "non-dippers," may be at greater risk for cardiovascular problems. We studied ...
Gosse P - - 1996
We have recently proposed a new method to evaluate the physical properties of arteries based on measurement of the QKD interval together with blood pressure and heart rate with an ambulatory blood pressure monitoring device. This interval is the time between the onset of the depolarization (QRS) on the electrocardiogram ...
Redon J - - 1996
OBJECTIVE: To analyse the discrepancies between casual and ambulatory blood pressure in hypertensive patients during treatment. PATIENTS AND METHODS: Patients were gathered intio two groups according to casual diastolic blood pressure (DBP) and antihypertensive treatment: group A (responders) with casual DBP < 90 mmHg administered one or more antihypertensive drugs ...
Fagard R - - 1996
OBJECTIVE: To assess the relationships of daytime and night-time blood pressures and the day-night pressure differences, obtained by various analytical methods, with the actual awake and asleep pressures and the awake-asleep pressure difference. METHODS: Ambulatory blood pressure was successfully monitored by use of the SpaceLabs 90202 device in 91 healthy ...
Veerman D P - - 1996
A relationship exists between blood pressure and cardiovascular morbidity and mortality. Recent data suggest that the variability of blood pressure is also related to hypertensive target organ damage. We studied the relationship of ambulatory daytime and night-time and supine beat-to-beat Finapres blood pressure variability to left ventricular mass index (LVMI) ...
Landau K - - 1996
OBJECTIVE: To define parameters of ambulatory diurnal blood pressure in patients who had experienced anterior ischemic optic neuropathy (AION) in a case-controlled study. PARTICIPANTS AND METHODS: Twenty-four patients with AION and 24 control subjects who were matched for age, gender, medical diagnoses, and medications underwent ambulatory automated blood pressure monitoring ...
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