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Adnadjevic Djordje D Laboratory for Musculoskeletal Pain and Motor Control, Center for Sensory-Motor Interaction (SMI), Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, - - 2014
During palpation, the pressure intensity and direction include minor deviations suggesting that standardized variations of the pressure intensity during pressure algometry may optimize the stimulus efficacy. This study examined the perceived pain outcome and reliability of a biaxial (bidirectional) algometer exerting rotational and vibratory stimulation on top of the basic ...
Back C C Stroke Unit, Department of Neurology, Copenhagen University Hospital, Glostrup, Denmark; Translational Stroke Center, Copenhagen University Hospital, Glostrup, - - 2014
Angiotensin II type 1 receptor blockade has neuroprotective effects in animal stroke models, but no effects in clinical stroke trials. We evaluated cerebral and peripheral changes in the renin angiotensin aldosterone system (RAAS) and stress responses in acute ischemic stroke patients. Blood from a jugular and cubital vein was collected ...
Qin Yu - - 2014
To identify risk factors, associations between dietary patterns, body mass index (BMI), and hypertension in a Chinese population. Dietary intake was assessed in 2518 adults by a 3-day 24 h recall and a food frequency questionnaire. Salt and oil intake was assessed by weighing records. Four dietary patterns were identified ...
Knoche Sebastian S TU Dortmund University, Department of Physics, 44221 Dortmund, Germany. - - 2014
We study the buckling of elastic spherical shells under osmotic pressure with the osmolyte concentration of the exterior solution as a control parameter. We compare our results for the bifurcation behavior with results for buckling under mechanical pressure control, that is, with an empty capsule interior. We find striking differences ...
Ren Wurong W Science and Technology on Advanced Ceramic Fibers and Composites Laboratory, College of Aerospace Science and Engineering, National University of Defense Technology, Changsha 410073, People's Republic of - - 2014
Pressure-tolerant polymer-glass microfluidic reactors with excellent bonding strength have been fabricated by the simultaneous solidification-bonding (SSB) method, in which a viscous and reactive matrix polymer was cast on the glass substrate with pre-patterned wax as a sacrificial template. Elaborate interfacial chemistry between the matrix polymer and the functionalized glass surface ...
Chazallon Bertrand - - 2014
Semi-clathrates of tetrabutylammonium bromide (TBAB) are investigated for their potential application in the CO2 capture context based on hydrate technology. The three-phase lines of semi-clathrates of CO2-TBAB-H2O and N2-TBAB-H2O are established simultaneously with the structure using in-situ Raman scattering performed at high pressure. The preferred crystal phase obtained at ambient ...
Rosier Peter F W M PF University Medical Centre Utrecht - Urology, The - - 2014
To present the evidence background for an ICS teaching module for the urodynamic analysis of voiding. Literature analysis and expert opinion are combined to collate an outline and explanation of a preferred and good urodynamic practice. Patient's preparation, pathophysiology, technique and principles of pressure flow analysis are summarized in this ...
Hajjar Ihab I Division of Geriatrics and General Internal Medicine, Department of Medicine, Emory University, Atlanta, Georgia, USA; - - 2014
Animal studies suggest that the renin-angiotensin-aldosterone system is involved in neurocognitive function and the response to antihypertensive therapy. We investigated the impact of circulating aldosterone and renin activity on cognition and cerebral hemodynamics at baseline and after antihypertensive therapy for 1 year. Participants were older adults (n = 47; mean ...
Mubarak Muhammed M Histopathology Department, Sindh Institute of Urology and Transplantation, Karachi, - - 2014
We read with great interest the article by Abdi-Ali et al. entitled "IgA nephropathy with early kidney disease is associated with increased arterial stiffness and renin-angiotensin system activity" in the recent issue of Journal of the Renin-Angiotensin-Aldosterone System. In a study on 10 normotensive IgA nephropathy (IgAN) subjects with early ...
Sampson Amanda K AK From the Director's Research Group (A.K.S., G.L.J.), Department of Vascular Pharmacology (A.K.S., K.L.A., J.P.F.C.-D.), Department of Neuropharmacology (G.A.H.), and Department of Diabetic Complications (M.C.T.), Baker IDI Heart and Diabetes Institute, Melbourne, Australia; and Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom (D.G., M.W.M., A.F.D.). - - 2014
The lineage of the Y chromosome accounts for up to 15 to 20 mm Hg in arterial pressure. Genes located on the Y chromosome from the spontaneously hypertensive rat (SHR) are associated with the renin-angiotensin system. Given the important role of the renin-angiotensin system in the renal regulation of fluid ...
McMonnies Charles C University of New South Wales, Sydney, New South Wales, Australia. Electronic address: - - 2014
The efficacy of intraocular pressure reduction in retarding the progression of glaucoma has been demonstrated. This review examines the potential for prognostic advantage for glaucoma suspects in reducing their optic nerve head exposure to elevated intraocular pressure associated with activities which have been shown to elevate intraocular pressure. In this ...
Lei Zhipeng Z 1.Human-Centric Design Research Laboratory Department of Mechanical Engineering Texas Tech University, Lubbock, TX 79409, - - 2014
Finite element (FE) filtering facepiece respirators (FFRs) were developed and mated to the new headforms with a cervical spine model. The FFRs from three manufacturers included three sizing systems: (i) a single one-size-fits all, (ii) an FFR with two sizes (S/M and M/L), and (iii) an FFR with three sizes ...
Nanidis Nikitas N Evangelismos General Hospital of Athens, Neurosurgical department of the University of Athens, D.Ralli str. 92-94, Piraeus, 18539, Greece, - - 2014
A novel flow-regulated external drain (FRED) was devised to overcome the problems of the pressure-regulated systems and serial lumbar taps. Eleven patients who underwent lumbar external drainage received a flow-regulated system using simple and inexpensive materials available in most hospital settings. The system proved to be reliable at removing a ...
Bogatko Stuart S Eenheid Algemene Chemie, Vrije Universiteit Brussel (VUB), Faculteit Wetenschappen, Pleinlaan 2, 1050 Brussels, Belgium. - - 2014
We have developed a simple model for incorporating the influence of external pressure and solution pH into a cluster based (i.e. comprising the central Al(3+) cation and nearest neighbor coordinating H2O and OH(-) ligands) 1st principles approach to investigate the hydrolysis equilibria of aqueous Al(3+) monomeric species in high pressure ...
O'Caoimh Rónán R Centre for Gerontology and Rehabilitation, University College Cork, St Finbarrs Hospital, Cork, - - 2014
With the rising prevalence of cognitive impairment worldwide clinicians are facing important challenges managing dementia, particularly Alzheimer's disease (AD), the most prevalent dementia subtype. Given that current treatments mainly offer symptomatic improvement, without altering disease progression, the challenge now is to identify and integrate new therapeutic strategies. Hypertension is increasingly ...
Ramirez Claudia E CE From the Department of Medicine, Division of Clinical Pharmacology and the Autonomic Dysfunction Center, Vanderbilt University School of Medicine, Nashville, Tennessee (C.E.R., L.E.O., A.C.A., A.G., A.D., S.R.R., D.R., I.B., C.A.S.); and Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee - - 2014
The clinical presentation of autonomic failure is orthostatic hypotension. Severely affected patients require pharmacological treatment to prevent presyncopal symptoms or frank syncope. We previously reported in a proof of concept study that pediatric doses of the norepinephrine transporter blockade, atomoxetine, increases blood pressure in autonomic failure patients with residual sympathetic ...
Azak Alper A Department of Nephrology, Ankara Education and Research Hospital, Ankara, - - 2014
Chronic Heart Failure (CHF) is highly prevalent and is associated with high morbidity and mortality rates. It has been well established that excessive intake of sodium chloride (salt) induced hypertension in some populations. Although salt seems to induce cardiovascular diseases through elevation of blood pressure, it has also been indicated ...
Safar M E ME Centre de Diagnostic et de Thérapeutique, Hôpital Hotel Dieu, 1 Place du Parvis Notre Dame, 75004, Paris, France, - - 2014
In recent years, treatment strategies for hypertension have often focused on combination therapies that include diuretics and renin angiotensin aldosterone system blockers such as angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. However, in clinical practice, a significant number of patients do not respond completely to these combination treatments, and long-term ...
Botella Pablo P Departamento de Física Aplicada-ICMUV, Universidad de Valencia , MALTA Consolider Team, Edificio de Investigación, C. Dr. Moliner 50, 46100 Burjassot, - - 2014
The high-pressure behavior of CaWO4 was analyzed at room temperature by Raman spectroscopy. Pressure was generated using a diamond-anvil cell and Ne as pressure-transmitting medium. The pressure range of previous studies has been extended from 23.4 to 46.3 GPa. The experiments reveal the existence of two reversible phase transitions. The ...
Li Xiao C XC The University of Mississippi Medical - - 2014
Caveolin 1 (CAV-1) functions not only as a constitutive scaffolding protein of caveolae but also as a vesicular transporter and signaling regulator. In the present study, we tested the hypothesis that CAV-1 knockout (CAV-1 KO) inhibits AT1 (AT1a) receptor-mediated uptake of angiotensin II (ANG II) in the proximal tubule and ...
Lokajíček Tomáš T Institute of Geology AS CR, v.v.i. Rozvojová 269, 165 00 Prague 6, Czech Republic. Electronic address: - - 2014
Knowledge of shear wave velocities in loaded rocks is important in describing elastic anisotropy. A new high-pressure measuring head was designed and constructed for longitudinal and traversal ultrasonic sounding of spherical rock samples in 132 independent directions under hydrostatic pressure up to 60MPa. The velocity is measured using a pair ...
Parati Gianfranco G Department of Health Sciences, University of Milano-Bicocca, Milan, Italy Department of Cardiovascular Neural and Metabolic Sciences, S.Luca Hospital, Istituto Auxologico Italiano, IRCCS, Milan, Italy - - 2014
Many hypertensive subjects travel to high altitudes, but little is known on ambulatory blood pressure (ABP) changes and antihypertensive drugs' efficacy under acute and prolonged exposure to hypobaric hypoxia. In particular, the efficacy of angiotensin receptor blockers in this condition is unknown. This may be clinically relevant considering that renin-angiotensin ...
Fagernaes C F CF Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, - - 2014
During the past decade, several population-based studies have found an inverse association between blood pressure (BP) and headache. However, most of them have a cross-sectional design or lack a validated definition of a headache-free population at baseline. Therefore, additional population-based studies using a clearly defined headache-free population and a prospective ...
Giridharan Guruprasad A GA 1Department of Bioengineering, University of Louisville, Louisville, KY; 2College of Mechanical Engineering, Purdue University, West Lafayette, IN; and 3Section of Cardiothoracic Surgery, Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis, - - 2014
Mechanical circulatory support - either ventricular assist device (VAD, left-sided systemic support) or cavopulmonary assist device (CPAD, right-sided support) - has been suggested as treatment for Fontan failure. The selection of left- vs. right-sided support for failing Fontan has not been previously defined.Computer simulation and mock circulation models of pediatric ...
Mironova Elena E Department of Physiology, University of Texas Health Science Center, San Antonio, Texas, - - 2014
Discretionary control of Na(+) excretion is a key component of the regulation of arterial blood pressure in mammals. Sodium excretion is fine-tuned in the aldosterone-sensitive distal nephron by the activity of the epithelial Na(+) channel (ENaC). Here, ENaC functions as a final effector of the renin-angiotensin-aldosterone system (RAAS) during negative ...
Webb Alastair J S AJ From the Stroke Prevention Research Unit, Oxford University, Oxford, United - - 2014
Visit-to-visit variability in systolic blood pressure (SBP) is associated with an increased risk of stroke and was reduced in randomized trials by calcium channel blockers and diuretics but not by renin-angiotensin system inhibitors. However, time of day effects could not be determined. Day-to-day variability on home BP readings predicts stroke ...
Devatkal Suresh S Central Institute of Postharvest Engineering and Technology (ICAR), Ludhiana, India - - 2014
High-pressure processing (300 MPa for 5 min) as a non-thermal post-processing intervention was employed to improve the shelf life and qualities of cooked refrigerated chicken nuggets. Pomegranate peel extract (1%) was also used as a source of natural antioxidant and antimicrobial in chicken nuggets. Microstructure, microbial profile, instrumental colour, texture profile and ...
Donnelly Joseph J Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Box 167, Cambridge, CB2 0QQ, UK, - - 2014
Increased blood glucose and impaired pressure reactivity (PRx) after traumatic brain injury (TBI) are both known to correlate with unfavorable patient outcome. However, the relationship between these two variables is unknown. To test the hypothesis that increased blood glucose leads to increased PRx, we retrospectively analyzed data from 86 traumatic ...
Schaich Chris L CL Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, North Carolina Hypertension & Vascular Research Center, Wake Forest School of Medicine, Winston-Salem, North - - 2014
We investigated acute and chronic effects of CB1 cannabinoid receptor blockade in renin-angiotensin system-dependent hypertension using rimonabant (SR141716A), an orally active antagonist with central and peripheral actions. In transgenic (mRen2)27 rats, a model of angiotensin II-dependent hypertension with increased body mass and insulin resistance, acute systemic blockade of CB1 receptors ...
Frantti J J Finnish Research and Engineering, Jaalaranta 9 B 42, 00180 Helsinki, - - 2014
Piezoelectric materials respond to external stimuli by adjusting atomic positions. In solid-solutions, the changes occurring in atomic scale are very complex since the short- and long-range order are different. Standard methods used in diffraction data analysis fail to model the short-range order accurately. Pressure-induced cation displacements in ferroelectric Pb(Zr0.45Ti0.55)O3 perovskite ...
Wu You Y Stevens Institute of - - 2014
With proteinaceous-liquid flooding of discrete alveoli, a model of the edema pattern in the acute respiratory distress syndrome, lung inflation over expands aerated alveoli adjacent to flooded alveoli. Theoretical considerations suggest that the over-expansion may be proportional to surface tension, T. Yet recent evidence indicates proteinaceous edema liquid may not ...
Zhao Liang L Department of Cardiovascular Surgery, Xinqiao Hospital, Third Military Medical University, 400037, Chongqing, - - 2014
Intestinal ischemia-reperfusion injury is one of the main factors leading to multiple organ failure after resuscitation of prolonged hemorrhagic shock; however, the current conventional fluid resuscitation still cannot effectively reduce intestinal injury caused by prolonged hemorrhagic shock. To investigate the effect of ECMO resuscitation on alleviating intestinal ischemia-reperfusion injury in ...
Ryu Jiwon J 0000-0003-0251-7858 Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, - - 2014
It is known that blood pressure variability (BPV) can independently affect target organ damage (TOD), even with normal blood pressure. There have been few studieson chronic kidney disease (CKD) patients. We evaluated the relationship between BPV and TOD in a cross-sectional, multicenter study on hypertensive CKD patients. We evaluated 1,173 ...
Griffin Karen A KA From the Departments of Medicine (K.A.G., A.P., A.K.B.) and Pathology (M.P.), Loyola University Chicago and Hines VA Hospital, Maywood, IL; Department of Medicine, University of Illinois Hospital, Chicago, IL (N.L.); and Department of Pathology, University of Texas Health Science Center, San Antonio, (M.A.V.). - - 2014
Most patients with essential hypertension do not exhibit substantial renal damage. Renal autoregulation by preventing glomerular transmission of systemic pressures has been postulated to mediate this resistance. Conversely, malignant nephrosclerosis (MN) has been postulated to develop when severe hypertension exceeds a critical ceiling. If the concept is valid, even modest ...
Fu Zhi Qing ZQ First Department of Geriatric Cardiovascular Diseases, Chinese PLA General Hospital, Beijing, - - 2014
The call for early detection of hypotension creates a heavy demand for new methods that can monitor trends in blood pressure (BP) levels continuously and noninvasively. Photoplethysmography (PPG) is widely used in hemodynamic analysis. We assessed the feasibility of toe PPG in tracing BP trends using BP readings obtained by ...
Fitzgerald C - - 2014
High-pressure water injuries of the oropharynx are uncommon but can cause significant injury and airway compromise when they occur. A small number of cases of high-pressure water injury of the oropharynx have been presented in the literature, detailing a range of effects and outcomes. We describe the first reported case ...
Husain Kazim K Kazim Husain, Leon Ferder, Department of Physiology, Pharmacology and Toxicology, Ponce School of Medicine and Health Sciences, Ponce, PR 00732, United - - 2014
Epidemiological, preclinical and clinical studies established the association between high alcohol consumption and hypertension. However the mechanism through which alcohol raises blood pressure remains elusive. Several possible mechanisms have been proposed such as an imbalance of the central nervous system, impairment of the baroreceptors, enhanced sympathetic activity, stimulation of the ...
Khan Md Abdul Hye MA Department of Pharmacology & Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA, - - 2014
Angiotensin II type 1 receptor blockers (ARBs) are widely used in treating hypertension. In the present study, we tested the hypothesis that a novel ARB, azilsartan medoxomil (AZL-M) will prevent renal and cardiovascular injury in the spontaneously hypertensive obese rat (SHROB), a model of cardiometabolic syndrome. Male SHROB were treated ...
Johnson Richard J RJ Division of Nephrology, Eastern Colorado Health Care System, Department of Veteran Affairs, 12700 East 19th Avenue, Room 7015, Aurora, CO 80045, - - 2014
An epidemic of chronic kidney disease (CKD) in Mesoamerica is providing new insights into the mechanisms by which salt and water might drive hypertension and CKD. Increasingly, evidence suggests that recurrent dehydration and salt loss might be a mechanism that causes CKD, and experimental studies suggest a key role for ...
Salcedo Levilester L Department of Colorectal Surgery and Department of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio, USA; Summa Cardiovascular Institute and Northeast Ohio Medical University, Akron, Ohio, USA; Advanced Platform Technology Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, - - 2014
This research demonstrates the regenerative effects of mesenchymal stem cells (MSCs) on the injured anal sphincter by comparing anal sphincter pressures following intramuscular and serial intravascular MSC infusion in a rat model of anal sphincter injury. Fifty rats were divided into injury (n = 35) and no injury (NI; n ...
Neuberger Eric J EJ Department of Neurology and Neurosciences, Rutgers New Jersey Medical School, Newark, New - - 2014
Traumatic brain injury (TBI) can occur from physical trauma from a wide spectrum of insults ranging from explosions to falls. The biomechanics of the trauma can vary in key features, including the rate and magnitude of the insult. Although the effect of peak injury pressure on neurological outcome has been ...
Lavieri Nicolas A NA Department of Animal Science, Iowa State University, Ames, Iowa 50011-3150, - - 2014
A sublethally injured bacterial cell has been defined as a cell that survives a stress such as heating, freezing, acid treatment, or other antimicrobial intervention but can repair the cellular damage exerted by the stressor and later regain its original ability to grow. Consequently, sublethally injured cells are not likely ...
Romero-Franco Natalia N Department of Health Sciences, University of Jaén, - - 2014
[Purpose] The aim of this study was to analyze stabilometry in athletes during an indoor season in order to determine whether injured athletes show different stabilometric values before injury than non-injured athletes in two different training periods (volume and pre-competition periods). [Subjects] The subjects were 51 athletes from Unicaja athletic ...
Camporesi Enrico M - - 2014
Therapeutic mechanisms of action for hyperbaric oxygen (HBO2) therapy are based on elevation of both the partial pressure of inspired O2 and of the hydrostatic pressure. This last mechanism contributes to a compression of all gas-filled spaces in the body (Boyle's Law) and is relevant to treat conditions where gas ...
Doaei Saeid S PhD Candidate, Faculty Member, School of Health, North Khorasan University of Medical Sciences, Bojnurd, - - 2014
Salt sensitivity of blood pressure (BP) is an independent risk factor for cardiovascular morbidity. Up to 50% of patients with essential hypertension are salt-sensitive, as manifested by a rise in BP with salt intake. Several genetic variations have been identified as being associated with salt sensitivity. The present study aimed ...
Li Bing Cang - - 2014
Objective: To study blast-induced traumatic brain injury (bTBI) characteristics in confined space. Methods: The goats were placed at the column-like buildings with trinitrotoluene (TNT) as the source of the blast wave. The pressure was recorded at 2-8 m from the explosion center. The systemic physiology, electroencephalogram (EEG), serum level of ...
Williams Monica M Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, - - 2014
Blood pressure can vary considerably during anesthesia. If blood pressure falls outside the limits of cerebrovascular autoregulation, children can become at risk of cerebral ischemic or hyperemic injury. However, the blood pressure limits of autoregulation are unclear in infants and children, and these limits can shift after brain injury. This ...
Patel Meeta M Department of Infection, Immunity and Inflammation, University of Leicester, Transplant Group, Leicester General Hospital, Leicester, - - 2014
Ex vivo normothermic perfusion (EVNP) can reverse some of the detrimental effects of ischemic injury. However, in kidneys with warm and cold ischemic injury the optimal perfusion pressure remains undetermined. The aim of this study was to evaluate the effects of two different arterial pressures during EVNP. Porcine kidneys underwent static ...
Sterenborg Thomas B - - 2014
Despite the increasing use of pre- and posthydration protocols and low-osmolar instead of high-osmolar iodine-containing contrast media, the incidence of contrast-induced nephropathy (CIN) is still significant. There is evidence that contrast media cause ischemia-reperfusion injury of the medulla. Remote ischemic preconditioning (RIPC) is a non-invasive, safe, and low-cost method to ...
Ehrmann Brett J BJ Division of Pediatric Nephrology, Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan Health System, Ann Arbor, - - 2014
Reports of the burden of hypertension in hospitalized children are emerging, but the prevalence and significance of this condition within the PICU are not well understood. The aims of this study were to validate a definition of hypertension in the PICU and assess the associations between hypertension and acute kidney ...
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