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Probst Tahira M - - 2013
Each year, more than 4 million U.S. workers are injured on the job - several thousand die (Bureau of Labor Statistics, 2008). Despite these staggering numbers, research suggests that they are gross underestimates of the true volume of workplace related illnesses and injuries due to accident under-reporting. Although accident under-reporting ...
Chaudhry Sonia - - 2013
High-pressure injection injuries often have a misleadingly benign presentation. However, it is important to recognize the potential surgical urgency and long-term sequelae associated with these injuries. We present a case of paint gun injection to the palm and review the literature on high-pressure paint injection injuries. The 3 factors most ...
Sirino─člu Hakan - - 2013
Abstract High-pressure injection injuries to the upper extremity cause potentially severe complications that result in multiple operations, amputations, and permanent functional deficits. Early exploration and debridement are the mainstays of treatment for optimal functional recovery. We describe the late presentation of a high-pressure cement injection injury to the hand, its ...
Dougherty Judith E - - 2013
Hyperbaric oxygen therapy has been approved for primary or adjunctive care in 14 indications. A hyperbaric environment exists when a patient's whole body is physically exposed to 100% oxygen and pressure that is greater than one atmosphere absolute. Hyperbaric oxygen therapy works through the ideal gas laws and is effective ...
Jones Claire F - - 2013
Background: Despite considerable effort over the last four decades, research has failed to translate into consistently effective treatment options for spinal cord injury (SCI). This is partly attributed to differences between the injury response of humans and rodent models. Some of this difference could be because humans have a discernible ...
Roberts Derek J - - 2013
Accumulating pre-clinical data suggests that matrix metalloproteinase (MMP) expression plays a critical role in the pathophysiology of secondary brain injury. We conducted a prospective multimodal monitoring study in order to characterize the temporal MMP response after severe traumatic brain injury (TBI) in 8 critically ill humans and its relationship with ...
Ritz Thomas - - 2013
Exposure to feared stimuli in blood-injection-injury (BII)-phobia is thought to elicit a diphasic response pattern, with an initial fight-flight-like cardiovascular activation followed by a marked deactivation and possible fainting (vasovagal syncope). However, studies have remained equivocal on the importance of such patterns. We therefore sought to determine the prevalence and ...
Ramsey Marc C MC Department of Mechanical Engineering, Vanderbilt University, VU Station B #351592, 2301 Vanderbilt Place, Nashville, Tennessee 37235-1592, - - 2013
A tabletop device uses 1.4 J to drive the symmetric collapse of a 1.8 mm radius vapor bubble in water at 22 bar. Single shot streak imaging reveals a stagnation plasma of 28 micron radius at over 12 000 K and an unprecedented pressure of 3.2 Mbar. Compared to sonoluminescence, the most commonly studied cavitation mechanism, ...
Beloncle François - - 2013
The optimal target blood pressure in septic shock is still unknown. Therefore, in a long-term, resuscitated porcine model of fecal peritonitis-induced septic shock, Corrêa and colleagues tested whether different titrations of mean arterial pressure (50 to 60 and 75 to 85 mm Hg) would produce different effects on sepsis-related organ ...
De Lamo-Castellví Silvia - - 2013
This study used flow cytometry (FC), epifluorescent microscopy (EM), and conventional culture media (PC) to evaluate the potential for high-pressure throttling (HPT) to produce injury in E. coli. E. coli cells suspended at a concentration of approximately 8 log (CFU/mL) in Butterfield's phosphate buffer and UHT skimmed milk, were treated ...
Zammit Christopher C - - 2013
Traumatic brain injury is the most common cause of death and disability in young people, with an annual financial burden of over $50 billion per year in the United States. Traumatic brain injury is defined by both the initial primary injury and the subsequent secondary injuries. Fundamental to emergency department ...
Niles Dana E - - 2013
INTRODUCTION: Single mode, pressure reduction (PR) crib mattresses are increasingly employed in hospitals to prevent skin injury and infection. However, single mode PR mattresses risk large mattress deflection during CPR chest compressions, potentially leading to inadequate chest compressions. HYPOTHESIS: New, dual mode PR crib mattress technology provides less mattress deflection ...
Gefen Amit - - 2013
Pressure ulcer prevention strategies include the prevention, and early recognition, of deep tissue injury (DTI), which can evolve into a Stage III or Stage IV pressure ulcer. In addition to their role in pressure-induced ischemia, shearing forces are believed to contribute substantially to the risk of DTI. Because the visual ...
White Nathan J NJ Division of Emergency Medicine, Harborview Medical Center, University of Washington, Seattle, Washington 98104, USA. - - 2013
Animal models of combined traumatic brain injury (TBI) and hemorrhagic shock (HS) suggest a benefit of hemoglobin-based oxygen carrier (HBOC)-based resuscitation, but their use remains controversial, and little is known of the specific effects of TBI and high-pressure (large arterial injury) bleeding on resuscitation. We examine the effect of TBI ...
Steele Catriona M - - 2013
The purpose of this study was to measure treatment outcomes in a group of six adults with chronic dysphagia following acquired brain injury, who each completed 24 sessions of tongue-pressure resistance training, over a total of 11-12 weeks. The treatment protocol emphasized both strength and accuracy. Biofeedback was provided using ...
Ralib Azrina M - - 2013
Aims: Treatment of renal anemia with erythropoietic stimulating agents sometimes increases blood pressure. It is uncertain whether this is due to direct vasoconstriction and/or increased red blood cell mass. Materials and methods: We conducted a post-hoc analysis of 160 critically ill patients in the EARLYARF trial with elevated urinary γ-glutamyltranspeptidase ...
Lehman Li-wei H - - 2013
Minimal clinical research has investigated the significance of different blood pressure monitoring techniques in the ICU and whether systolic vs. mean blood pressures should be targeted in therapeutic protocols and in defining clinical study cohorts. The objectives of this study are to compare real-world invasive arterial blood pressure with noninvasive ...
Nakagawa Takashi - - 2013
Although renal denervation (RD) is shown to reduce blood pressure significantly in patients with resistant hypertension, the benefit of RD in prevention of stroke is unknown. We hypothesized that RD can prevent the incidence of stroke and brain injury in hypertensive rats beyond blood pressure lowering. High-salt-loaded, stroke-prone, spontaneously hypertensive ...
Bidani Anil K AK Loyola University and Hines VA Hospital, Maywood, Illinois 60153, USA. - - 2013
Despite apparent blood pressure (BP) control and renin-angiotensin system (RAS) blockade, the chronic kidney disease (CKD) outcomes have been suboptimal. Accordingly, this review is addressed to renal microvascular and autoregulatory impairments that underlie the enhanced dynamic glomerular BP transmission in CKD progression. Clinical data suggest that failure to achieve adequate ...
Ramkumar Nirupama N Division of Nephrology, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, - - 2013
Although the existence of a complete intrarenal renin-angiotensin system is now well established, its role in modulating tubule sodium transport and blood pressure is incompletely understood. Several recent studies have shed light on one component of the system, proximal tubule-derived angiotensinogen (AGT). This review discusses the synthesis, regulation and function ...
Espina Laura - - 2012
This work addresses the inactivation achieved with Escherichia coli O157:H7 and Listeria monocytogenes EGD-e by combined processes of high hydrostatic pressure (HHP) and essential oils (EOs) or their chemical constituents (CCs). HHP treatments (175-400MPa for 20min) were combined with 200μL/L of each EO (Citrus sinensis L., Citrus lemon L., Citrus ...
Bruijns Stevan Raynier - - 2012
BACKGROUND: Raised blood pressure (and heart rate (HR)) due to anxiety in a clinical situation is well described and is called the white coat effect (WCE). It is not known whether the pain and anxiety that results from trauma causes a measurable WCE. METHODS: A sample of patients with a ...
Brotfain Evgeni - - 2012
ABSTRACT: Treatment of combined traumatic brain injury and hypovolemic shock, poses a particular challenge due to the possible conflicting consequences. While restoring diminished volume is the treatment goal for hypovolemia, maintaining and adequate cerebral perfusion pressure and avoidance of secondary damage remains a treatment goal for the injured brain. Various ...
Ono Takahiko - - 2012
Oxidative stress and peritubular capillary (PTC) injury are involved in the progression of chronic kidney disease (CKD). We investigated protective effects of Shichimotsu-koka-To (SKT), a Japanese traditional Kampo prescription, against nephrosclerosis and hypertension on a CKD model due to irreversible nephritis. Six-week-old male Wistar rats were subjected to uninephrectomy, and ...
Saraf Sanjay - - 2012
The high-pressure injection injuries are unusual injuries and the extent of tissue damage is often under estimated. They represent potentially disabling forms of trauma and have disastrous effects on tissues if not treated promptly. We present a case of high pressure injection injury to the finger from lubricant oil. The ...
Chaturvedi Lakshmi S LS Department of Surgery, Michigan State University, Lansing, MI, - - 2012
Traumatic brain injury induces a neuroinflammatory response frequently associated with increased intracranial pressure. The aim of this study was to investigate the effects of alcohol and increased extracellular pressure on murine BV-2 microglial proliferation and cytokine responses to lipopolysaccharide (LPS) stimulation. BV-2 cells were cultured under 0 or 30 mm ...
Wood Matthew - - 2013
Transportation vehicles, whether they are passenger vehicles or heavy trucks and transport vehicles, rely upon rubber tires to negotiate the roadways and surfaces on which they are driven. These tires have the potential of sudden rupture resulting from various causes including but not limited to over-pressurization, sidewall failures, or punctures ...
Lv Faqin - - 2012
BACKGROUND: This research aimed to study the assessment of local muscle microcirculation perfusion of extremities that underwent crush injuries by using contrast-enhanced ultrasonography (CEUS). METHODS: A total of 28 New Zealand rabbits were anesthetized by using intramuscular pentobarbital sodium (30 mg/kg). A balloon cuff device was used to create crush ...
de Rougemont O - - 2012
BACKGROUND & AIMS: The aim of this study was to identify protective mechanisms of cold machine perfusion in liver grafts donated after cardiac death. METHODS: Pig livers exposed to 60 min warm ischemia were cold stored for 7 h or treated after 6 h cold storage by 1 h hypothermic ...
Satou Ryousuke R Department of Physiology and Hypertension and Renal Center of Excellence; Tulane University Health Sciences Center; New Orleans, LA - - 2012
The renin-angiotensin system (RAS) plays important roles in blood pressure control and tissue disease. An inappropriate local angiotensin II elevation in the kidneys leads to the development of hypertension, tissue damage and chronic injury. Studies have demonstrated that the JAK-STAT pathway mediates angiotensin II-triggered gene transcription. The JAK-STAT pathway in ...
Gingell-Littlejohn M - - 2012
Delayed graft function (DGF) is a major issue in kidney transplantation and is associated with reduced graft and patient survival. The condition results from the summative effects of multiple injurious processes associated with transplantation with many underlying factors being nonmodifiable. Reducing cold ischemic time and machine perfusion have decreased the ...
McWilliams R Stewart - - 2012
The structural and chemical properties of the bi-molecular, hydrogen-bonded, nitrogen-rich energetic material triaminoguanidinium 1-methyl-5-nitriminotetrazolate C(3)H(12)N(12)O(2) (TAG-MNT) have been investigated at room pressure and under high pressure isothermal compression using powder x-ray diffraction and Raman and infrared spectroscopy. A stiffening of the equation of state and concomitant structural relaxation between 6 ...
Heaton James T - - 2012
OBJECTIVES/HYPOTHESIS: Vocal fold (VF) injections of viscous materials are typically performed using hand-operated syringes or injection guns; however, these methods can be imprecise due to accumulation of pressure, effort-related tremor, and poor feedback regarding injection volume and rate. STUDY DESIGN: Apparatus development with laboratory bench-top and animal model testing. METHODS: ...
Kalkan B - - 2012
The compressibility and phase stability of Y bB(2) are investigated under high pressure using high-resolution synchrotron x-ray diffraction in a diamond anvil cell. The bulk modules of high purity Y bB(2) is obtained as ∼182 GPa using the Birch-Murnaghan equation of state. The patterns measured up to 20 GPa and the pressure ...
Ma Jun - - 2012
A miniature fiber-tip pressure sensor was built by using an extremely thin graphene film as the diaphragm. The graphene also acts as a light reflector, which, in conjunction with the reflection at the fiber end-air interface, forms a low finesse Fabry-Perot interferometer. The graphene based sensor demonstrated pressure sensitivity over ...
Byard Roger W - - 2013
The commercial fishing industry has one of the highest injury and mortality rates of all occupational areas. This results from the nature of the work involving vessels often manned by only a few individuals who are working with heavy-duty equipment in dangerous environments at all hours. Economic pressures may force ...
Pavan Barbara - - 2012
NMR is the technique of election to probe the local properties of materials. Herein we present the results of density functional theory (DFT) ab initio calculations of the NMR parameters for fluorapatite (FAp), a calcium orthophosphate mineral belonging to the apatite family, by using the GIPAW method (Pickard and Mauri, ...
Quraishi Abdul Haque M AH Government Medical College, 22, Vijaynagar, Chhaoni, Nagpur 440013 - - 2014
High pressure injection injury of the hand looks rather innocuous but has the potential of affecting the function. The radiological picture is quite alarming and it gives a fair idea about the extent of the damage. The description and the images which follow, emphasize the need for an early and ...
Hikal Walid M - - 2012
Non-isothermal measurements of thermodynamic parameters and vapor pressures of low-volatile materials are favored when time is a crucial factor to be considered, such as in the case of detection of hazardous materials. In this article, we demonstrate that optical absorbance spectroscopy can be used non-isothermally to estimate the thermodynamic properties ...
Bennani Vincent - - 2012
Handling properties of cordless gingival displacement materials is not well understood, resulting in incorrect use. Insufficient displacement of the gingival margin may result in a poor impression. This study investigated the pressure generated by a cordless displacement paste with respect to different techniques. Two chambers with dimensions of 5 × ...
Enmark Martin - - 2012
Enantiomeric separation of omeprazole has been extensively studied regarding both product analysis and preparation using several different chiral stationary phases. In this study, the preparative chiral separation of omeprazole is optimized for productivity using three different columns packed with amylose tris (3,5-dimethyl phenyl carbamate) coated macroporous silica (5, 10 and ...
Sun Zhimei - - 2012
With the advent of big synchrotron facilities around the world, pressure is now routinely placed to design a new material or manipulate the properties of materials. In GeTe, an important phase-change material that utilizes the property contrast between the crystalline and amorphous states for data storage, we observed a reversible ...
Wang Yi - - 2012
Objective: To investigate the material properties of normal and degenerated intervertebral discs (IVDs) and examine the effect of degenerative changes on IVD pathology. Methods: A computer-based online search was undertaken to identify English articles about material properties of IVDs published from January 1950 to 2011 in PubMed database. The retrieved ...
Vanhecke D - - 2012
We describe how high-pressure freezing of infectious biological material can safely be accomplished with the help of membrane carriers. The method described is easy to perform; however, careful manipulations are required. Existing safety regulations must still be followed. However, the procedure reduces the risk of dissemination of infectious material.
Sun Liling - - 2012
Pressure has an essential role in the production and control of superconductivity in iron-based superconductors. Substitution of a large cation by a smaller rare-earth ion to simulate the pressure effect has raised the superconducting transition temperature T(c) to a record high of 55 K in these materials. In the same way ...
Flower Oliver - - 2012
Several different classes of sedative agents are used in the management of patients with traumatic brain injury (TBI). These agents are used at induction of anaesthesia, to maintain sedation, to reduce elevated intracranial pressure, to terminate seizure activity and facilitate ventilation. The intent of their use is to prevent secondary ...
Tan Robert - - 2012
We are developing an in vivo pressure sensor that measures the change in conductance of a deformable electrolyte-filled catheter resulting from external pressure. The sensor design and materials are easily scaled and inexpensive. The compact, in vivo nature of the device may result in the compact instrumentation being unobtrusively affixed ...
Sen Indu I Anaesthesia and Intensive Care Department, Post Graduate Institute of Medical Education and Research, Chandigarh, - - 2012
Posttraumatic intravasation of fat and debris can lead to a cascade of events. Hydroxyethyl starches (HES) markedly suppress neutrophil influx by decreasing pulmonary capillary permeability and facilitating tissue oxygenation by improving microcirculation. It was hypothesized that in hypoxemic femur injury patients undergoing operative stabilization, HES administration will prevent the deterioration ...
Malkoun Mario - - 2011
Current heel protection devices used in the operating room do not comply with the consensus document of the European and National (North American) Pressure Ulcer Advisory Panels. A complying prototype has been tested. Prospective cohort study comparing interface pressures. While using the prototype device, the heel interface pressure is significantly ...
Dell'italia Louis J - - 2011
The title of the proposed series of reviews is Translational Success Stories. The definition of "translation" according to Webster is, "an act, process, or instance of translating as a rendering of one language into another." In the context of this inaugural review, it is the translation of Tigerstedt's and Bergman's(1) ...
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