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Duburcq Thibault - - 2014
IntroductionBased on the potential interest in sodium lactate as an energy substrate and resuscitative fluid, we investigated the effects of hypertonic sodium lactate in a porcine endotoxic shock.MethodsFifteen anesthetized, mechanically ventilated pigs were challenged with intravenous infusion of E. coli endotoxin. Three groups of five animals were randomly assigned to ...
Imbalzano Egidio E Department of Internal Medicine and Medical Therapy, University of Messina, Italy - - 2014
The aim of this study was to assess the antihypertensive efficacy and safety of aliskiren versus ramipril or losartan in hypertensive patients with type 2 diabetes mellitus, microalbuminuria and uncontrolled hypertension, despite the use of optimal conventional antihypertensive therapy. In this open-label active comparator study, 126 patients were randomly assigned ...
Matsumura Kiyoshi K Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University , Fukuoka , Japan - - 2014
Abstract It has been shown that losartan, an angiotensin II receptor blocker (ARB), reduces serum uric acid levels. However, the effects of losartan on serum uric acid levels in the patients treated with a thiazide diuretic have not been fully elucidated. We have investigated the effects of losartan compared with ...
Baki Elif Dogan ED Department of Anesthesiology, Afyon Kocatepe University, Faculty of Medicine, Afyon, Turkey. Electronic address: - - 2014
Pneumoperitoneum (PNP) and patient positions required for laparoscopy can induce pathophysiological changes that complicate anesthetic management during laparoscopic procedures. This study investigated whether low tidal volume and positive end-expiratory pressure (PEEP) application can improve ventilatory and oxygenation parameters during laparoscopic surgery. A total of 60 patients undergoing laparoscopic surgery were ...
Ela Yüksel Y 1 Department of Anesthesiology and Reanimation, Afyon Kocatepe University , Afyon, Turkey - - 2014
Abstract Background: To study the effects of low tidal volume with positive end-expiratory pressure (PEEP) on arterial blood gases of patients undergoing laparoscopic urologic surgeries. Subjects and Methods: Eighty-six laparoscopic urologic patients were enrolled in this study. Patients were randomized into two groups according to the ventilatory settings. In the ...
Bhosale Vivek V VV Scientist, Clinical and Experimental Medicine, CSIR-Central Drug Research Institute , Lucknow, India - - 2014
Hypertension, "The silent killer" is a multifactorial disorder which is asymptomatic and if left untreated leads to lethal complications. Nebivolol is a third generation beta blocker with additional vasodilating property due to nitric oxide release. The current study aims to assess efficacy and safety of Nebivolol and compare with Atenolol. ...
Johnson M A MA Sport, Health and Performance Enhancement (SHAPE) Research Group, School of Science and Technology, Nottingham Trent University, Nottingham, NG11 8NS, UK, - - 2014
This study examined the effects of an active cycling warm-up, with and without the addition of an inspiratory muscle warm-up (IMW), on 10-km cycling time-trial performance. Ten cyclists ([Formula: see text] = 65 ± 9 mL kg(-1) min(-1)) performed a habituation 10-km cycling time-trial and three further time-trials preceded by either no warm-up (CONT), a cycling-specific warm-up ...
Yang Chun-Kang CK Department of Abdominal Surgery, Fujian Provincial Cancer Hospital, Fuzhou, 350014, Fujian, China, - - 2014
To investigate thymidine kinase 1(TK-1) and Ki67 expression levels of human colorectal carcinoma cells line SW480 after exposure to a simulated laparoscopic carbon dioxide (CO2) pneumoperitoneum environment at different pressures and lengths of exposure time. The effects of the simulated laparoscopic CO2 pneumoperitoneum environment at different CO2 pressures (6, 9, ...
Hithamani Gavirangappa G Department of Biochemistry and Nutrition, CSIR - Central Food Technological Research Institute, Mysore 570 020, - - 2014
Finger millet (Eleusine coracana) and pearl millet (Pennisetum glaucum) were evaluated for polyphenolic content and their bioaccessibility. Total polyphenols of native finger millet was 10.2mg/g which reduced by 50% after sprouting or pressure-cooking, while 12-19% reduction was seen after open-pan boiling. Total flavonoids of the grain reduced drastically on sprouting, ...
Liu Ning - - 2014
Here we report that TiO2 nanotube (NT) arrays, converted by a high pressure H2 treatment to anatase-like 'black titania' show a high open-circuit photocatalytic hydrogen production rate without the presence of a co-catalyst. Tubes converted to 'black titania' using classic reduction treatments (e.g. atmospheric pressure H2/Ar annealing) do not show ...
Kim Sang Hui - - 2014
We propose a 1-dimensional (1D) nanofluidic energy conversion device by implementing a surface-patterned Nafion membrane for the direct energy conversion of the pressure to electrical power. By implementing a -200-nm-thick nano-bridge with a 5-nm pore size between two microfluidic channels, we acquired an effective streaming potential of 307 mV and ...
Chen Hong H Department of Biomedical Engineering, Columbia University, New York, New York, - - 2014
Focused ultrasound (FUS) in combination with microbubbles (MBs) has been successfully used in the delivery of various-size therapeutic agents across the blood-brain barrier (BBB). This study revealed that FUS-induced BBB opening size, defined by the size of the largest molecule that can permeate through the BBB, can be controlled by ...
Choi Sang Bong SB *Department of Internal Medicine, Division of Respirology, Sanggye Paik Hospital, Inje University College of Medicine Departments of ‡Thoracic and Cardiovascular Surgery §Surgery ∥Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul †Department of Internal Medicine, Division of Respirology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, - - 2014
To determine whether the incidence of postoperative pulmonary complications increases in patients with high peak airway pressure (≥30 cm H2O) during laparoscopic colectomy, we investigated consecutive patients with colorectal cancer who had undergone laparoscopic colectomy. Of the 115 enrolled patients, 34 patients (30%) had peak airway pressure ≥30 cm H2O ...
Takahara Mitsuyoshi M Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Suita City, Osaka, - - 2014
We investigated whether 10 mg per day of azilsartan, one-half of the normal dosage, would be non-inferior to 8 mg per day of candesartan cilexetil for controlling blood pressure in Japanese patients with hypertension. In this open-label, randomized, crossover trial, 309 hypertensive Japanese adults treated with 8-mg candesartan cilexetil were randomized into ...
Schlader Zachary J ZJ Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital of Dallas, 7232 Greenville Ave, Dallas, TX, 75231, - - 2014
To test the hypothesis that those who are highly tolerant to lower body negative pressure (LBNP) while normothermic are also highly tolerant to this challenge while hyperthermic. Sixty pairs of normothermic and hyperthermic LBNP tests to pre-syncope were evaluated. LBNP tolerance was quantified via the cumulative stress index (CSI), which ...
Yavuzkir Mustafa Ferzeyn MF Department of Cardiology, School of Medicine, Firat University, Elazig, - - 2014
To compare the mean platelet volume (MPV; a general marker of platelet activation) in groups of patients with and without hypertension and to analyse its relationship with left ventricular mass index (LVMI). This cross-sectional, observational study enrolled newly diagnosed patients with untreated stage I-II hypertension and healthy control subjects without ...
Fang Hong H Department of Cardiology - - 2014
Abstract Background: Combined treatment of a calcium antagonist and α/β-adrenoreceptor blocker is expected to offer some advantages in the management of hypertension; however, their antihypertensive efficacy and safety remain relatively under-explored. Methods: The current study addresses the 24-h antihypertensive efficacy and safety of arotinolol combined with a different calcium channel ...
Sieverdes John C JC 1 Medical University of South Carolina , Technology Applications Center for Healthful Lifestyles, Charleston, - - 2014
Abstract Objective: Evidence is accumulating, predominantly among clinical trials in adults, that yoga improves blood pressure (BP) control, with downregulation of the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic nervous system (SNS) projected as underlying mechanisms. This pilot study assessed whether Hatha yoga has the potential to reduce BP among youth ...
Yang Xiao-Chen XC Department of Cardiology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, - - 2014
To evaluate the effectiveness and safety of Songling Xuemaikang Capsule (, SXC) for the treatment of primary hypertension. An extensive search including Cochrane Library, PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Chinese Biomedical Literature Database (CBM), Chinese National Knowledge Infrastructure (CNKI), Chinese Scientifific Journal Database (VIP), KoreaMed, Japanese database, ...
Hypolito Octavio O Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brazil. Electronic address: - - 2014
to evaluate the clinical, hemodynamic, gas analysis and metabolic repercussions of high transient pressures of pneumoperitoneum for a short period of time to ensure greater security for introduction of the first trocar. sixty-seven patients undergoing laparoscopic procedures were studied and randomly distributed in P12 group: n=30 (intraperitoneal pressure [IPP] 12mmHg) ...
Karkhaneh Akbar A 2 Biomedical Engineering Faculty, Science and Research Branch, Islamic Azad University, Tehran - - - 2014
The objective of this study was to determine the effects of hydrostatic pressure (HP) on the biochemical properties and gene expression of mesenchymal stem cells (MSCs) on scaffolds for cartilage tissue engineering composed of poly(caprolactone) (PCL) poly(vinyl alcohol) (PVA) gelatin (GEL) semi interpenetrating polymer network (semi-IPN). The MSCs were cultured ...
Jiang Xian X Department of Physiology and Pathophysiology, Yanbian University College of Medicine, Yanji 133002, China; Department of Otolaryngology, Yanbian University College of Clinical Medicine, Yanji 133000, - - 2014
Blood pressure is maintained by the interaction between the arterial baroreflexes and the vestibulo-cardiovascular reflexes during postural changes. In this study, the influence of the vestibular receptors on the maintenance of blood pressure following acute hypotension was quantitatively compared with the role of baroreceptors in terms of c-Fos protein expression ...
Ito Takayasu T Department of Internal Medicine, Kuwana East Medical Center , Kuwana, Mie , Japan - - 2014
Abstract Background: A direct renin inhibitor (DRI), aliskiren, may be effective for blood pressure (BP) control in hemodialysis patients. However, it is unclear whether aliskiren has a greater beneficial effect on BP and humoral factors than angiotensin II receptor antagonists (ARBs) in hypertensive patients on hemodialysis. Methods: Eighteen hemodialysis patients ...
Hagins Marshall M Department of Physical Therapy, Long Island University, Brooklyn, - - 2014
The purpose of this study was to compare the effects of yoga with an active control (nonaerobic exercise) in individuals with prehypertension and stage 1 hypertension. A randomized clinical trial was performed using two arms: (1) yoga and (2) active control. Primary outcomes were 24-hour day and night ambulatory systolic ...
Malvasi A A Department of Obstetrics and Gynecology, Santa Maria Hospital, Bari, Italy. - - 2014
The supplemental administration of myo-inositol, D-chiro-inositol, folic acid and manganese (MDFM) was tested in a prospective, randomized, double-blind, placebo controlled clinical trial, pilot study, to test the hypothesis that its supplemental administration in the second trimester of pregnancy would improve glucose and glycemic parameters and blood pressure. Non-obese uniparous healthy ...
Maniotis Christos C 2nd Cardiology Department, "Hellenic Red Cross" Hospital of Athens, - - 2014
This study surveyed the frequencies of single nucleotide polymorphisms (SNPs) M235T AGT and C825T GNB3, and their association with insulin resistance, other biochemical markers and qualitative variables in subjects with high normal blood pressure and/or prehypertension in the Greek population. 330 men and women of Greek origin were divided into ...
Yang Xiaochen X Department of Cardiology, Guanganmen Hospital, China Academy of Chinese Medical Sciences, No. 5 Beixiange, Xicheng District, Beijing 100053, - - 2014
Objective. A systematic review of randomized controlled trials has been performed to assess the effectiveness of stimulation of acupoint KI 1 by Artemisia vulgaris (the Japanese name is moxa) to lower blood pressure compared to antihypertensive drugs. Methods and Findings. Articles published from 1980 to August 2013 in databases of ...
Sunagawa Katsunori K Faculty of Agriculture, University of the Ryukyus, 1 Senbaru, Nishihara-cho, Okinawa 903-0213, - - 2014
While there are persistent rumors that the consumption of goat meat dishes increases blood pressure, there is no scientific evidence to support this. Two experiments were conducted to clarify whether or not blood pressure increases in conjunction with the consumption of goat meat dishes. In experiment 1, 24 Dahl/Iwai rats ...
Goldsby Heather J HJ Department of Biology, University of Washington, Seattle, Washington, United States of America; BEACON Center for Evolution in Action, Michigan State University, East Lansing, Michigan, United States of - - 2014
Within nature, many groups exhibit division of labor. Individuals in these groups are under seemingly antagonistic pressures to perform the task most directly beneficial to themselves and to potentially perform a less desirable task to ensure the success of the group. Performing experiments to study how these pressures interact in ...
Xu Jingsong J Research Institute of Cardiovascular Diseases and Department of Cardiology, Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People's Republic of - - 2014
The postural change of pulse pressure (PP) in the persons with orthostatic hypertension (OHT) is unclear. This study included 2849 (65.0 ± 9.3 years) community participants. Blood pressures (BPs) in supine and standing positions were measured. The differences between upright and supine BP and PP were recorded as ΔBP and ΔPP. The criteria ...
Grainger Megan N C MN Department of Chemistry, University of Waikato, Private Bag 3105, Hamilton, New - - 2014
The effect of high pressure processing (HPP) on the conversion of dihydroxyacetone (DHA) to methylglyoxal (MGO) was examined in New Zealand mānuka honey and models thereof. The objective was to confirm that previously reported increases of MGO with HPP treatment originated from conversion of DHA. RP-HPLC was used to quantify ...
Yang Chun-Kang CK Department of Abdominal Surgery, Fujian Provincial Cancer Hospital, Fuzhou, Fujian 350014, China; Provincial Clinical College, Fujian Medical University, Fuzhou, Fujian 350014, - - 2013
The ability of pneumoperitoneum in laparoscopic surgery to promote proliferation and metastasis of colorectal cancer has become a focus of research in the field of minimally invasive surgery. The aim of this research was to investigate the effect of CO2 pneumoperitoneum under different pressures and exposed times on the expression ...
Kuriyama Satoru - - 2013
Applying a direct renin inhibitor (DRI) to advanced stage chronic kidney disease (CKD) patients is a matter of controversy. The purpose of this study was to evaluate the effect of the DRI, aliskiren, in patients with therapy-resistant hypertension undergoing hemodialysis (HD). The study was a prospective, randomized multicenter trial exploring ...
Wang Shutao - - 2013
Focused ultrasound, in the presence of microbubbles, has been used non-invasively to induce reversible blood-brain barrier (BBB) opening in both rodents and non-human primates. This study was aimed at identifying the dependence of BBB opening properties on polydisperse microbubble (all clinically approved microbubbles are polydisperse) type and distribution by using ...
- - 2013
The most challenging aspect of intravenously-administered drugs currently developed to treat central nervous system (CNS) diseases is their impermeability through the blood���brain barrier (BBB), a specialized vasculature system protecting the brain microenvironment. Focused ultrasound (FUS) in conjunction with systemically administered microbubbles has been shown to open the BBB locally, noninvasively, ...
Beshel Favour N - - 2013
The effects of chronic consumption of three types of palm oil diets on glomerular filtration rate (GFR), renal plasma flow (RPF) and blood pressure were studied. Wistar rats were randomly assigned into four groups of ten rats each, respectively: control, fresh (FPO), photoxidized (PPO), thermoxidized (TPO) palm oil diet-fed rats. ...
Conway Valérie - - 2013
Milk fat globule membrane (MFGM) found in buttermilk is rich in unique bioactive proteins. Several studies suggest that MFGM proteins possess biological activities such as cholesterol-lowering, antiviral, antibacterial, and anticancer properties, but data in humans are lacking. Furthermore, to our knowledge, no study has yet investigated the antihypertensive potential of ...
Chen Yi-Yu - - 2013
To observe the effect of Qingxuan Granule () on blood pressure variability of hypertensive patients with and without obstructive sleep apnea (OSA). This study was a stratified, randomized, doubled-blind, placebo-controlled clinical trial. Ninety mild and moderate hypertensive patients with yin deficiency and yang hyperactivity syndrome were enrolled. Each patient received ...
Khan Asim Ali AA Department of Moalejat(Medicine), Faculty of Medicine, Jamia Hamdard, New Delhi, - - 2013
The aim of this study is to evaluate the efficacy of a Unani formulation in hypertension. A total of 90 patients with total cholesterol level of more than 220 mg/dl with associated conditions were included in this study. A total of 30 patients having a mean systolic blood pressure (BP) ...
Du Shuang-Kui - - 2013
Ground cotton stalks were pretreated with sodium hydroxide (NaOH) at concentrations of 1-4% (w/v), pressures of 30-130kPa, durations of 15-75min, and liquid/solid ratios of 10:1-30:1. Modeling of the high pressure assist-alkali pretreatment (HPAP) of cotton stalk was attempted. The levels of NaOH concentration, pressure, and duration were optimized using a ...
Kim Eung Ju - - 2013
Renin-angiotensin system (RAS) blockers have shown clinical outcomes superior to those of the beta (β)-blocker atenolol, despite similar reductions in the peripheral blood pressure (BP), perhaps because of different impacts on central hemodynamics. However, few comparative studies of RAS blockers and newer vasodilating β-blockers have been performed. We compared the ...
Ashraf Rizwan - - 2013
The present study evaluated the effects of garlic on blood pressure in patients with essential hypertension. Patients (n=210) with stage 1 essential hypertension were divided into 7 groups named as A, B, C, D, E, F and G. Each group comprised of 30 patients. Each patient in group A, B, ...
Lan Yan - - 2013
Contribution of the vestibular end organ to regulation of arterial pressure was quantitatively compared with the role of baroreceptors in terms of baroreflex sensitivity and c-Fos protein expression in the rostral ventrolateral medulla (RVLM). Baroreflex sensitivity and c-Fos protein expression in the RVLM were measured in conscious rats that had ...
Khattab Ahmed A - - 2013
Aims: To investigate a pressure-controlled intermittent coronary sinus occlusion (PICSO) system in an ischaemia/reperfusion model. Methods and results: We randomly assigned 18 pigs subjected to 60 minutes ischaemia by left anterior descending (LAD) coronary artery balloon occlusion to PICSO (n=12, groups A and B) or to controls (n=6, group C). ...
Louër Anne-Claire - - 2013
We investigate the preconcentration profiles of a fluorescein and bovine serum albumine derivatized with this fluorescent tag in a microfluidic chip bearing a nanoslit. A new preconcentration method in which a hydrodynamic pressure is added to both electroosmotic and electrophoretic contributions is proposed to monitor the location of the preconcentration ...
Chapovsky P L - - 2013
A theoretical model of the nuclear spin isomer conversion in C2H4 induced by the intramolecular spin-spin interaction between hydrogen nuclei has been developed. In the ground electronic state, C2H4 has four nuclear spin isomers in contrast to two isomers in the molecules studied so far in this field of research. ...
Mozaffari-Khosravi Hassan - - 2013
ABSTRACT Introduction: The use of herbal medicines including different types of tea is among the different strategies for preventing and controlling the side-effects of diabetes. The aim of the present study was to compare the effect of sour tea and green tea on mildly hypertensive patients with diabetes. Methods: The ...
Chen Ting - - 2013
Combination therapy is an effective method to reduce the blood pressure (BP) for patients with hypertension. This study was performed to evaluate the efficacy and safety of benazepril/lercanidipine compared with benazepril alone in patients with mild-to-moderate hypertension. One hundred and eighty-one patients with mild-to-moderate primary hypertension were assigned in this ...
Feng Chao-Hui - - 2013
The effects of agitation (1002rpm), different pressure reduction rates (60 and 100mbar/min), as well as employing cold water with different initial temperatures (IWT: 7 and 20°C) on immersion vacuum cooling (IVC) of cooked pork hams were experimentally investigated. Final pork ham core temperature, cooling time, cooling loss, texture properties, colour ...
Oigman Wille - - 2013
BACKGROUND: Fixed-dose combinations of antihypertensive agents demonstrate advantages in terms of efficacy, tolerability, and treatment adherence. OBJECTIVE: This study was designed to compare the efficacy and safety of 2 ramipril and hydrochlorothiazide (HCTZ) fixed-dose combinations in patients with hypertension stage 1 or 2. Patients' blood pressure (BP) profiles were evaluated ...
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