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Mihata Teruhisa - - 2012
Although deviations in scapular orientation are thought to predispose to shoulder injuries in throwing athletes, the biomechanical mechanism underlying shoulder injuries in throwing athletes with an altered scapular orientation remains unclear. Seven fresh-frozen cadaveric shoulders were evaluated at 90° of abduction, with the humerus externally rotated from 90° to the ...
Guralnick Amy - - 2012
One of the underappreciated causes of hypertension is disordered sleep. There have been a number of studies evaluating sleep in the context of blood pressure control, and these will be reviewed. Original novel articles document that disruption of deep sleep stage, regardless of cause, if chronic, contributes to an increased ...
Jan Danser A H - - 2012
This review examines the evidence that plasma renin and/or prorenin level may be used to guide therapy in hypertension and as an independent risk factor for future cardiovascular events. A large number of retrospective analyses of patient populations in clinical trials, in whom 'baseline' renin measurements were available, supports that ...
Davidson Andrew C - - 2012
The number of Americans with hypertension is growing, and within that group there remain a growing number of patients with resistant hypertension. This growth has occurred despite numerous pharmacologic advancements and innovative therapies. Resistant hypertension carries a significant risk of morbidity and mortality. An interventional approach to treating patients with ...
Arnold Amy C - - 2012
Supine hypertension is a common finding in autonomic failure that can worsen orthostatic hypotension and predispose to end-organ damage. This review focuses on nonpharmacologic and pharmacologic approaches to manage hypertension in these patients in the face of disabling orthostatic hypotension. The hypertension of autonomic failure can be driven by sympathetic-dependent ...
Opotowsky Alexander R - - 2012
Pulmonary hypertension (PH) has diverse causes with heterogeneous physiology compelling distinct management. Differentiating patients with primarily elevated pulmonary vascular resistance (PVR) from those with PH predominantly because of elevated left-sided filling pressure is critical. We reviewed hemodynamics, echocardiography, and clinical data for 108 patients seen at a referral PH clinic ...
Bishop Steven M - - 2012
BACKGROUND:: Physiologic instability is a common clinical problem in the critically ill. Many natural feedback systems are nonlinear, and seemingly random fluctuations may result from the amplification of external perturbations or even arise de novo as a consequence of their underlying dynamics. Characterization of the underlying nonlinear state may be ...
Fuchs Hans - - 2012
Surgical treatment of functional single-ventricle heart disease with a modified Fontan procedure results in elevated central venous pressure. The case report describes a 19-year-old boy with hypoplastic left heart syndrome and Fontan palliation that resulted in frequent debilitating headaches after transcatheter closure of systemic venous-to-pulmonary venous collaterals. Measured increased intracranial ...
Asayama Kei - - 2012
Hypertension guidelines recommend blood pressure self-measurement at home (HBP), but no previous trial has assessed cardiovascular outcomes in hypertensive patients treated according to HBP. The multicenter Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure (HOMED-BP; 2001-2010) trial involved 3518 patients (50% women; mean age 59.6 years) ...
O'Brien Nicole F - - 2012
OBJECTIVE:: Type 1 diabetes mellitus is the most common chronic disease of childhood. Diabetic ketoacidosis is a well-known complication of diabetes mellitus and can be associated with devastating cerebral edema resulting in severe long-term neurologic disability. Despite the significant morbidity and mortality associated with this condition, relatively few treatments are ...
Donovan Anne L - - 2012
PURPOSE OF REVIEW: Cerebrovascular disease is a common cause of death and disability worldwide. The current literature supports an association between blood pressure (BP) and patient outcome during acute stroke. This review will provide an overview of the evidence to guide BP management during acute stroke. RECENT FINDINGS: Hypotension and ...
Feldstein Carlos A - - 2012
Epidemiological studies suggest an association between chronic blood pressure (BP) changes and Alzheimer's disease (AD). In particular, there is growing evidence that hypertensive people that do not have their BP adequately treated and controlled in midlife are more likely to develop AD in late-life. It has been hypothesized that cerebrovascular ...
Karadsheh Feras - - 2012
Thiazide and thiazide-like diuretics have been widely used as blood pressure-lowering agents for more than 5 decades. However, their use in patients with advanced chronic kidney disease has been limited and often discouraged. The exact mechanism of how thiazide and thiazide-like diuretics lower blood pressures is still in question. Emerging ...
Davila Evelyn P - - 2012
OBJECTIVE:: The role of occupation in the management of cardiovascular risk factors including hypertension is not well known. METHODS:: We analyzed the 1999-2004 National Health and Nutrition Examination Survey data of 6928 workers aged 20 years or older from 40 occupational groups. Hypertension was defined as measured blood pressure of ...
Tamburrini G - - 2012
The protocols for clinical evaluation and management of children with complex craniosynostoses are significantly different from those used in single suture forms. The time at which the various anatomical and functional anomalies observed in the affected subjects become clinically relevant varies from patient to patient, consequently requiring a tailored approach. ...
Widimsky Jr J - - 2012
Primary aldosteronism (PA) is a common form of arterial hypertension with a high prevalence of cardiovascular complications. In patients with PA, complex mechanisms may lead to functional and/or structural abnormalities of the blood vessel wall. Clinical evidence indicates that patients with PA may have immune cell activation, increased oxidative stress, ...
Lansdown Andrew - - 2012
SUMMARY: Polycystic ovary syndrome (PCOS) is a common endocrine condition associated with long-term health risks including type 2 diabetes and vascular dysfunction in addition to reproductive sequelae. Many of the common features of PCOS, such as central obesity, hyperinsulinaemia and obstructive sleep apnoea (OSA) are associated with chronic sympathetic overactivity, ...
Mimouni-Benabu Olivia - - 2012
OBJECTIVE: Congenital tracheal stenosis is a rare but severe condition with tracheal narrowing. There is no absolute correlation between luminal diameter and prognosis, and therapeutic decisions are difficult for intermediate cases. The aim of this study was to develop a dynamic model of the ventilatory consequences of congenital tracheal stenosis ...
Levine Steven M - - 2012
OBJECTIVE: This study aims to use the evidenced-based approach to better understand the surgical management and treatment of pressure ulcers. SUMMARY OF BACKGROUND DATA: Pressure sores are a cause of significant morbidity in the medical community. Although there are a multitude of preventative and treatment options, there remains some degree ...
Kallet R H - - 2012
Several recent studies have advanced our understanding of dead-space ventilation in patients with acute lung injury/acute respiratory distress syndrome (ALI/ARDS). They have demonstrated the utility of measuring physiologic dead-space-to-tidal volume ratio (VD/VT) and related variables in assessing outcomes as well as therapeutic interventions. These studies have included the evaluation of ...
Jackson George L GL Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center, Durham, NC 27705, USA. - - 2012
African Americans are significantly more likely than whites to have uncontrolled hypertension, contributing to significant disparities in cardiovascular disease and events. The goal of this study was to examine whether there were differences in change in blood pressure (BP) for African American and non-Hispanic white patients in response to a ...
Lago Rivero N - - 2012
To describe the case of treatment with amlodipine in a poorly controlled hypertension in a pediatric patient diagnosed with tricodistrofia. Girl 5 years old, diagnosed of tricodistrofia included within the Tay-Sachs syndrome. As a consequence of a cardiac arrest suffered in the context of a respiratory distress syndrome associated with ...
Larochelle P - - 2012
Inhibitors of the vascular endothelial growth factor (vegf-is) signalling pathway have fundamentally changed the treatment of metastatic renal cell carcinoma (mrcc). Hypertension is one of the most common side effects of vegf-is and has been reported with almost every vegf-i used for treatment to date. The exact mechanism of vegf-i-induced ...
Randerath Winfried J - - 2012
The coexistence of obstructive sleep apnea (OSA) and central sleep apnea (CSA) and Cheyne-Stokes respiration (CSR) is common in patients with heart failure (HF). While CPAP improves CSA/CSR by about 50%, maximal suppression is crucial in improving clinical outcomes. Auto-servoventilation (ASV) effectively suppresses CSA/CSR in HF, but few trials have ...
Tomlinson Laurie A LA Clinical Pharmacology Unit, Addenbrooke's Hospital, Cambridge, UK. - - 2012
Although blood pressure measured at the brachial artery plays a central role in our understanding and management of cardiovascular risk, in recent years great emphasis has been placed on the importance of central blood pressure. It seems straightforward that knowledge of the blood pressure directly affecting the major organs is ...
Khader Ali - - 2012
Objective  Recording and reporting systems borrowed from the DOTS framework for tuberculosis control can be used to record, monitor and report on chronic disease. In a primary healthcare clinic run by UNRWA in Amman, Jordan, serving Palestine refugees with hypertension, we set out to illustrate the method of cohort reporting ...
Mallick Salman Rasheed - - 2012
Ambulatory blood pressure (BP) monitoring is superior to clinic BP monitoring in predicting long-term consequences of hypertension. This has raised interest in diurnal variation in BP and elevation in nighttime BP as a prognostic and therapeutic target. Several studies have identified prevalence of nocturnal hypertension in patients with accelerated progression ...
Marik Paul E - - 2012
BACKGROUND: Airway pressure release ventilation (APRV) is an alternative approach to the low-tidal volume "open-lung" ventilation strategy. APRV is associated with a higher mean airway pressure than conventional ventilation and has therefore not been evaluated in patients with acute neurological injuries. METHODS: Case report. RESULTS: We report a patient with ...
Altun Bülent - - 2012
Background : In the Chronic REnal Disease In Turkey -CREDIT Study, a large populationbased study on 10,748 adults, the prevalence of chronic kidney disease (CKD) and relationship between CKD and other cardiovascular risk factors had been studied. Methods : This report presents the results of CREDIT study on the prevalence, ...
Andrén Ann - - 2012
BACKGROUND: Continuous positive airway pressure treatment has been shown to lower blood pressure (BP) in patients with obstructive sleep apnea (OSA). The aims of the present pilot study were to evaluate the potential effects of oral appliance (OA) therapy on BP, to assess various outcome BP measures, and to inform ...
Baydur Ahmet - - 2012
PURPOSE OF REVIEW: This review emphasizes key findings in physiologic research of sarcoidosis reported over the past year. RECENT FINDINGS: Sarcoidosis, a multiorgan disease involving the formation of epithelioid-cell granulomas, is characterized by reduced lung volumes, compliance, and diffusion capacity (DLCO), and, in a small number of cases, by airflow ...
Burk Ruth Srednicki - - 2012
Pressure ulcers and ventilator-associated pneumonia (VAP) are both common in acute and critical care settings and are considerable sources of morbidity, mortality, and health care costs. To prevent pressure ulcers, guidelines limit bed backrest elevation to less than 30 degrees, whereas recommendations to reduce VAP include use of backrest elevations ...
Kennelly Sean - - 2012
Vascular risk factors are implicated in the pathogenesis of Alzheimer's disease (AD). There is an age-dependent relationship between blood pressure and the risk of AD. Given the potential temporal lag that can exist between the two conditions, longitudinal population studies offer the best opportunity to identify a causal relationship. Midlife ...
Stepanikova Irena - - 2012
This study examined two types of potential sources of racial-ethnic disparities in medical care: implicit biases and time pressure. Eighty-one family physicians and general internists responded to a case vignette describing a patient with chest pain. Time pressure was manipulated experimentally. Under high time pressure, but not under low time ...
Odudu Aghogho - - 2012
There is a widely held belief that hypervolaemia due to excess intake or inadequate removal of salt and water is the principal cause of hypertension in dialysis patients. The risk of failing to consider additional pathophysiological elements is that inadequate or inappropriate therapeutic strategies may be adopted. This review aims ...
Trinh Victoria T - - 2012
INTRODUCTION: High intracranial compliance states requiring negative pressure drainage, otherwise known as low-pressure hydrocephalus syndromes, are rare conditions. The use of siphoning, enabled by revision to an adjustable shunt without an anti-siphon device, has been largely unexplored in low-pressure hydrocephalus. METHODS: Three patients with presumed normal pressure hydrocephalus (NPH) presented ...
Krakoff Lawrence R - - 2012
Effective drug treatment of hypertension for prevention of fatal and non-fatal cardiovascular disease passed its 50(th) anniversary two years ago(1). Until recently, the most consistent observation among trials had been that stroke risk was directly related to the fall in blood pressure on treatment(2). Older trials established the value of ...
Srinivasan Sushant - - 2012
ABSTRACT: Symptomatic cerebral edema from diabetic ketoacidosis occurs infrequently but carries a high rate of mortality and morbidity owing to complications from intracranial hypertension. Treatment options are limited but include hyperosmolar therapy with mannitol or hypertonic saline, tracheal intubation for airway protection, and hyperventilation via mechanical ventilation. We describe here ...
Dellavale Damián - - 2012
Single-bubble sonoluminescence (SBSL) was explored under a variety of multifrequency excitations. In particular, biharmonic excitation was used to produce SBSL for unprecedented low dissolved noble gas concentrations in a sulfuric acid solution. Reducing the amount of dissolved noble gas makes it possible to reach higher acoustic pressures on the SL ...
Swope Rachel - - 2012
Orthostatic hypotension, a symptomatic drop in blood pressure on standing, can have detrimental effects for orthopedic patients in the postoperative period. It is essential for orthopedic practitioners to understand the causes, risk factors, treatment options, and prevention techniques for orthostatic hypotension.
Yoon Seok Hwa - - 2012
Septic patients portray instable hemodynamic states because of hypotension or cardiomyopathy, caused by vasodilation, thus, impairing global tissue perfusion and oxygenation threatening functions of critical organs. Therefore, it has become the primary concern of anesthesiologists in conducting anesthesia (induction, maintenance, recovery, and postoperative care), especially in the induction of those ...
Sharma Jai Prakash - - 2012
Tourniquets are commonly used in limb surgeries, be it orthopedic or plastic surgeries. But the inflation pressures, the duration, and release guidelines are still not clear. According to a survey, majority of orthopedic surgeons inflate the tourniquet to fixed pressures for the upper and the lower limbs without considering the ...
Viera Anthony J - - 2012
Resistant hypertension (RH) is defined as blood pressure above a goal despite adherence to at least 3 optimally dosed antihypertensive medications of different classes, one of which is a diuretic. Evaluation of possible RH begins with an assessment of adherence to medications. The white-coat effect should be ruled out by ...
Saugel Bernd - - 2012
PURPOSE: The T-Line TL-200 (Tensys Medical, San Diego, CA, USA) is a non-invasive arterial blood pressure (BP) monitoring system allowing continuous "beat-to-beat" monitoring of systolic arterial pressure (SAP), mean arterial pressure (MAP), and diastolic arterial pressure (DAP). It provides a real-time BP waveform like that obtained using an arterial catheter. ...
Ginelli P - - 2012
Diastolic dysfunction is present in half of patients with hypertension and has been shown to be associated with increased cardiovascular morbidity and mortality, as well as the development of heart failure. With the high prevalence of hypertension and its associated complications, treatment of diastolic dysfunction in hypertension is an important ...
Daugherty Stacie L - - 2012
Patients with resistant hypertension are at risk for poor outcomes. Medication adherence and intensification improve blood pressure (BP) control; however, little is known about these processes or their association with outcomes in resistant hypertension. This retrospective study included patients from 2002 to 2006 with incident hypertension from 2 health systems ...
Maclaughlin Helen L - - 2012
BackgroundThe effectiveness of lifestyle-based weight loss programs in obese patients with chronic disease has not been widely studied. This study examined the effectiveness of a weight management program (WMP), and sought to determine factors associated with successful weight loss in obese patients with chronic kidney disease (CKD).MethodsIn this prospective cohort ...
Burke Gordon M - - 2012
Systemic hypertension is a common cardiovascular problem that often cannot be fully treated with existing non-pharmacologic and pharmacologic measures. A catheter-based strategy which denervates the renal afferent and efferent autonomic nervous system has been developed for the treatment of drug-resistant hypertension. In early clinical trials this procedure was shown to ...
Alqadri Syeda L - - 2012
Spontaneous intracerebral hemorrhage (ICH) is intra-parenchymal bleeding that may lead to localized hematoma formation. The hematoma can enlarge over a period of time, and directly contribute to neurological deterioration and death. Several studies have shown a relationship between acute hypertensive response and poor prognosis among patients with ICH; however, it ...
Duan Melissa - - 2012
Dexmedetomidine is a selective alpha-2 receptor agonist that possesses both sedative and analgesic properties with minimal respiratory depression. We report the successful administration of dexmedetomidine on a 16 year-old primigravida woman that allowed the patient to tolerate application of bilevel positive airway pressure ventilation in treatment of acute hypoxemic respiratory ...
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