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Reant Patricia P Bordeaux Cardiology University Hospital-CIC0005, Bordeaux University, Bordeaux, France, - - 2014
Longitudinal strain analysis enables early detection of left ventricular (LV) contraction abnormalities in patients with preserved ejection fraction. Hypertrophic cardiomyopathy (HCM) is associated with low values of regional and global longitudinal myocardial deformations. In addition to contraction abnormalities, LV regional strain abnormalities are partially related to the degree of hypertrophy. ...
Jones Chad A CA Department of Chemistry and Biochemistry, Brigham Young University, C100 Benson Science Building, Provo, Utah, 84602-5700, - - 2014
Pressure measurement is often the limiting factor in the accuracy of quantitative ion-molecule experiments. We present a new method for pressure measurement based on analysis of pressure-limited Fourier transform ion cyclotron resonance (FTICR) linewidths for well-characterized collisions of Ar(+) with Ar. The kinetic energy dependence of Ar(+)/Ar collision cross sections ...
Gorący Iwona I Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, Szczecin. - - 2014
The natriuretic peptides play a key role in the modulation left ventricular mass (LVM) and blood pressure (BP). We hypothesized that NPPA (natriuretic peptide precursor A gene), NPPB (natriuretic peptide precursor B gene) and NPPC (natriuretic peptide precursor C gene) are candidate genes possibly involved in the development or modulating ...
Jackson Edwin K EK From the Department of Pharmacology and Chemical Biology, University of Pittsburgh, School of Medicine, PA. - - 2014
Because the effects of dipeptidyl peptidase 4 (DPP4) inhibitors on blood pressure are controversial, we examined the long-term effects of sitagliptin (80 mg/kg per day) on blood pressure (radiotelemetry) in spontaneously hypertensive rats (SHR), Wistar-Kyoto rats, and Zucker Diabetic-Sprague Dawley rats (metabolic syndrome model). In SHR, chronic (3 weeks) sitagliptin ...
Ameer Omar Z OZ The Australian School of Advanced Medicine, Macquarie University, Sydney, New South Wales, - - 2014
We examined whether increased sympathetic nerve activity (SNA) accounts for enhanced depressor responses to ganglionic blockade in the Lewis polycystic kidney (LPK) model of chronic kidney disease (CKD) or whether it reflects increased vascular responses to vasodilation (vascular amplifier). Under urethane anesthesia, depressor responses to ganglionic blockade (hexamethonium, 0.5-40 mg/kg ...
Dean Dennis A - - 2014
Blood pressure (BP) may be adversely affected by a variety of sleep disturbances, including sleep fragmentation, hypoxemia, respiratory disturbances, and periodic limb movements. We aim to identify which polysomnography indices are most strongly and consistently associated with systolic and diastolic blood pressure (SBP, DBP) levels in a population-based sample. Cross-sectional ...
Sheppard James Peter JP Nuffield Department of Primary Care Health Sciences, NIHR School for Primary Care Research, University of Oxford, Oxford, UK; Primary Care Clinical Sciences NIHR School for Primary Care Research, University of Birmingham, Edgbaston, Birmingham, UK; - - 2014
An exaggerated morning blood pressure surge (MBPS) may be associated with stroke and other cardiovascular events, but the threshold at which an MBPS becomes pathological is unclear. This study aimed to systematically review the existing literature and establish the most appropriate definition of pathological MBPS. A MEDLINE search strategy was ...
Igreja Bruno B Department of Research and Development, BIAL-Portela & Cª, S.A., S. Mamede do Coronado, - - 2014
Hyperactivation of the sympathetic nervous system has an important role in the development and progression of arterial hypertension. This study evaluated the efficacy of etamicastat, a dopamine-β-hydroxylase (DβH) inhibitor, in controlling high blood pressure in the spontaneously hypertensive rat (SHR), either alone or in combination with other classes of antihypertensives. ...
Reynolds P S PS Departments of Anesthesiology 1, Emergency Medicine 2, Physiology 3, Virginia Commonwealth University Medical Center, Richmond - - 2014
Trauma mortality may be increased in the presence of pre-existing diseases such as chronic hypertension. We hypothesized that systemic and microvascular alterations accompanying chronic hypertension would increase the vulnerability to hemorrhage relative to normotensive controls in a rat model of hemorrhagic shock. We present a novel comparative hemorrhage model of ...
Zou Guangrong G Union Clinical Medical College, Fujian Medical University , Fuzhou, Fujian , China - - 2014
Abstract Spontaneously hypertensive rats (SHR) was used to study left ventricular hypertrophy (LVH) and its dynamic change after the interventions with Telmisartan and Amlodipine. The results showed that the expression of TRPC1, CaN and NFATC3 increased gradually with the pathogenesis and progression of LVH. Telmisartan reduced blood pressure and LVH, ...
Omari T T School of Medicine, Flinders University, Bedford Park, Australia ; The Robinson Institute, University of Adelaide, Adelaide, Australia ; Translational Research Center for Gastrointestinal Diseases, University of Leuven, - - 2014
Dysphagia is a common reason for referral for investigations of oesophageal motility. Impedance measurement has now been incorporated into commercially available diagnostic manometry systems for more than a decade. This innovation, which offered the ability to record patterns of bolus transport without the need for simultaneous radiology, has for the ...
Trzcinka Agnieszka A From the *Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; †Department of Anesthesiology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire; and ‡Missoula Anesthesiology, Missoula, Montana; and §International Heart Institute of Montana, Missoula, - - 2014
A comprehensive transesophageal echocardiographic (TEE) examination is essential for the evaluation of a mitral valve (MV) repair. The edge-to-edge MV repair (i.e., Alfieri stitch) can pose a unique challenge in assessing iatrogenic mitral stenosis, especially when an asymmetric double-orifice is created. The reliability of the simplified Bernoulli equation for evaluating ...
Geraldes Vera V Faculty of Medicine & Centro de Cardiologia of University of Lisbon, - - 2014
It is well established that sympathetic nervous system is responsible for the onset, development and maintenance of neurogenic hypertension. The rostroventrolateral medulla (RVLM) and medullo-cervical pressor area (MCPA) are important central sympathoexcitatory regions whose role on neurogenic hypertension remains unknown. To establish RVLM and MCPA roles in the long-term regulation ...
Kirby Anna C AC From the *Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Reproductive Medicine, UC San Diego Health System, La Jolla; and †Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Kaiser Permanente, San Diego, - - 2014
Female stress urinary incontinence is caused by urethral dysfunction during dynamic conditions, but current technology has limitations in measuring urethral pressures under these conditions. An 8-French high-resolution manometry (HRM) catheter currently in clinical use in gastroenterology may accurately measure urethral pressures under dynamic conditions because it has a 25-millisecond response ...
Agnoletti D D Paris Descartes University, AP-HP, Diagnosis and Therapeutic Center, Hôtel-Dieu, Paris, France. Department of Internal Medicine, University of Bologna, Bologna, - - 2014
Pulse wave analysis is a pivotal tool to estimate central haemodynamic parameters. Available commercial devices use applanation tonometry and have been validated against invasive catheterism. We previously observed differences on a radial second systolic peak (rSPB2) between two commonly used devices: SphygmoCor (AtCor, Australia) and PulsePen (DiaTecne, Italy). The aim ...
Downes Stephen S National Physical Laboratory, Hampton Road, Teddington TW11 0LW, - - 2014
In theory, shock tubes provide a pressure change with a very fast rise time and calculable amplitude. This pressure step could provide the basis for the calibration of pressure transducers used in highly dynamic applications. However, conventional metal shock tubes can be expensive, unwieldy and difficult to modify. We describe ...
Bombelli Michele M From the Clinica Medica, Dipartimento di Scienze della Salute, Università Milano-Bicocca, Milano, Italy (M.B., D.F., E.T., M.M., M.C., R.F., R.D., G.G., G.M.); Istituto di Ricerca a Carattere Scientifico IRCCS Multimedica, Sesto San Giovanni (Milano), Milano, Italy (G.G.); and Istituto Auxologico Italiano, Milano, Italy - - 2014
Cardiovascular events have their greatest prevalence in the early morning period. Whether this is attributable to an arousal-dependent blood pressure (BP) increase is far from being clear. It is also not clear to what extent this phenomenon reflects overall 24-hour BP variability. In 2051 subjects (aged 25-74 years) representative of ...
Cha Yong-Jun YJ Department of Physical Therapy, College of Natural Science, Daejeon University, 62 Daehackro, Dong-Gu, Daejeon 302-111, Republic of Korea. Electronic address: - - 2014
A cane has been used to improve hemiplegic gait by assisting affected limb to smoothly shift body mass toward the sound limb. The purpose of this study was to compare the walking parameters of patients after stroke while walking using traditionally recommended cane lengths that is fitted to the height ...
Abdollahzade Majid - - 2014
In this paper, we present and validate a data-driven method to lossy tube-load modeling of arterial tree in humans. In the proposed method, the lossy tube-load model is fitted to central aortic and peripheral blood pressure waves in the time domain. For this purpose, we employ a time-domain lossy tube-load ...
Penny A M AM School of GeoSciences, University of Edinburgh, West Mains Road, Edinburgh EH9 3JW, UK. - - 2014
Reef-building in metazoans represents an important ecological innovation whereby individuals collectively enhance feeding efficiency and gain protection from competitors and predation. The appearance of metazoan reefs in the fossil record therefore indicates an adaptive response to complex ecological pressures. In the Nama Group, Namibia, we found evidence of reef-building by ...
Rimaud D D Département de médecine physique et de réadaptation, hôpital Bellevue, 42055 Saint-Étienne cedex 02, France. Electronic address: - - 2014
Compression therapy has precise technical characteristics but in vivo pressures exerted by bandages are still poorly understood. To perform in vivo pressure measurements of different compression bandages bearing different technical characteristics with different application methods. Interface pressure was measured on the lower limb of 20 healthy women at 3 different ...
Procheş Serban S Discipline of Geography, University of KwaZulu-Natal, Westville Campus, PO Box X54001, Durban 4000, South Africa Environmental and Life Sciences Programme, Universiti Brunei Darussalam, Jalan Tungku Link 1410, Brunei Darussalam - - 2014
We use dated phylogenetic trees for tetrapod vertebrates to identify lineages that shifted between terrestrial and aquatic ecosystems in terms of feeding or development, and to assess the timing of such events. Both stem and crown lineage ages indicate a peak in transition events in correspondence with the K-Pg mass ...
Gritti Fabrice F Department of Chemistry, University of Tennessee, Knoxville, TN 37996-1600, - - 2014
The effect of the pressure on the dispersion of a low molecular weight compound along 0.508 and 1.016mm i.d. × 50cm long open circular tubes was investigated theoretically and experimentally. The theoretical predictions were based on the early models of dispersion derived by Aris and Taylor (1953) and on the ...
Lorente Leonardo - - 2014
The use of a system for continuous control of endotracheal tube cuff pressure reduced the incidence of ventilator-associated pneumonia (VAP) in one randomized controlled trial (RCT) with 112 patients but not in another RCT with 142 patients. In several guidelines on the prevention of VAP, the use of a system ...
Revel G M GM DIISM, Università Politecnica delle Marche, Ancona, - - 2014
The present paper proposes a new characterization technique for air-coupled ultrasound probes. The technique is based on a shock tube to generate a controlled pressure wave to calibrate transducers within their operating frequency range. The aim is to generate a high frequency pressure wave (at least up to 200kHz) with ...
Wang Jidong J Beijing Engineering Research Center for BioNanotechnology & Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing, 100190, China. xingyujiang@nanoctr.cn - - 2014
This report describes a straightforward but robust tubing method for connecting polydimethylsiloxane (PDMS) microfluidic devices to external equipment. The interconnection is irreversible and can sustain a pressure of up to 4.5 MPa that is characterized experimentally and theoretically. To demonstrate applications of this high-pressure tubing technique, we fabricate a semicircular ...
Grabenbauer Markus M Institute for Anatomy and Cell Biology Germany, University of Heidelberg, Heidelberg, - - 2014
High-pressure freeze fixation is the method of choice to arrest instantly all dynamic and physiological processes inside cells, tissues, and small organisms. Embedded in vitreous ice, such samples can be further processed by freeze substitution or directly analyzed in their fully hydrated state by cryo-electron microscopy of vitreous sections (CEMOVIS) ...
Papazova Diana A DA Department of Nephrology & Hypertension, University Medical Center Utrecht, Utrecht, The - - 2014
While the presence of oxidative stress in chronic kidney disease (CKD) is well established, its relation to hypertensive renal hemodynamics remains unclear. We hypothesized that once CKD is established blood pressure and renal vascular resistance (RVR) no longer depend on reactive oxygen species. CKD was induced by bilateral ablation of ...
Aquila Marco M Department of Bioscience, University of Milan, Milan, - - 2014
Whole-cell recording is the most widely used configuration of the patch recording technique, mainly because it allows to manipulate the intracellular environment while recording membrane current. However, the patch pipette tapered shank and the small tip opening give high access resistances and preclude efficient exchange between pipette solution and cell ...
Zhang Hexuan H Center for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, Third Military Medical University, Chongqing Institute of Hypertension, Chongqing, China (H.Z., Y.P., J.C., Y.C., F.S., Z.Z., Q.L., T.Y., C.M., Z.L., L.L., Z.Y., D.L., - - 2014
We investigated the hypothesis that the favorable effects of gastrointestinal (GI) intervention on hypertension (HTN) and cardiovascular (CV) disturbances are mediated by antagonizing overdrive of the sympathetic nervous system (SNS). Hypertensive patients with metabolic disturbances underwent laparoscopic Roux-en-Y gastric bypass surgery, and spontaneously hypertensive rats (SHRs) underwent RYGB or sham ...
Bakker Erik N T P EN Department of Biomedical Engineering and Physics, Academic Medical Center, Amsterdam, the - - 2014
Spontaneously hypertensive rats (SHR) have been used frequently as a model for human essential hypertension. However, both the SHR and its normotensive control, the Wistar Kyoto rat (WKY), consist of genetically different sublines. We tested the hypothesis that the pathophysiology of vascular remodeling in hypertension differs among rat sublines. We ...
Nagayama Tomomi T Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, - - 2014
Objective. Many previous clinical studies have suggested that atrial fibrillation (AF) is closely associated with hypertension. However, the benefits of antihypertensive therapy on AF are still inconsistent, and it is necessary to explore the factors augmenting AF in hypertensive rats. The aim of the present study was to investigate the ...
Foulquier Sébastien S Université de Lorraine, CITHÉFOR "Drug targets, formulation and preclinical assessment," EA3452, Faculté de Pharmacie, Nancy, - - 2014
Chronic hypertension decreases internal diameter of cerebral arteries and arterioles. We recently showed that short-term treatment with the angiotensin II receptor blocker telmisartan restored baseline internal diameter of small cerebral arterioles in spontaneously hypertensive rats (SHR), via reversal of structural remodeling and inhibition of the angiotensin II vasoconstrictor response. As ...
Ikeda C M CM Department of Mechanical Engineering , University of Maryland , College Park, MD 20742, - - 2013
The implosion of cylindrical shell structures in a high-pressure water environment is studied experimentally. The shell structures are made from thin-walled aluminium and brass tubes with circular cross sections and internal clearance-fit aluminium end caps. The structures are filled with air at atmospheric pressure. The implosions are created in a ...
Lourenço Isabela Scali - - 2013
To compare pressure-support ventilation with spontaneous breathing through a T-tube for interrupting invasive mechanical ventilation in patients undergoing cardiac surgery with cardiopulmonary bypass. Adults of both genders were randomly allocated to 30 minutes of either pressure-support ventilation or spontaneous ventilation with "T-tube" before extubation. Manovacuometry, ventilometry and clinical evaluation were ...
Adi Na - - 2013
The study objective was to evaluate endotracheal tubes (ETT) from extubated adult patients and compare them to new, unused, size-matched control tubes for changes in inspiratory resistance (Rinsp) and peak inspiratory pressure (PIP) before and immediately after suctioning with the Airway Medix Closed Suction System (AMCSS) (Biovo Technologies, 2013 Tel ...
Nichols Michael D MD Department of Biomedical Engineering, Center for Biomolecular and Tissue Engineering, Duke University, Durham, North Carolina, - - 2013
In this study, the coagulation-induced resistance to flow in small-diameter nonpermeable Tygon tubes and permeable expanded polytetrafluoroethylene (ePTFE) vascular grafts was characterized by measuring the upstream pressure needed to purge the coagulum from the tube lumen. This purging pressure was monitored using a closed system that compressed the contents of ...
Kanotra Sohit P - - 2013
Objective: To assess the risk of aspiration using a novel valve circuit that dynamically modulates endotracheal tube cuff pressure during the ventilatory cycle using bench and live animal models. Study Design: Animal model Methods: The bench model consisted of a cuffed endotracheal tube inserted into an artificial trachea. Leakage of ...
Patricia King Jie Hung - - 2013
Coptotermes curvignathus Holmgren is capable of feeding on living tree. This ability is attributed to their effective digestive system that is furnished by the termite's own cellulolytic enzymes and cooperative enzymes produced by their gut microbes. In this study, the identity of an array of diverse microbes residing in the ...
Matsuda Yu - - 2013
The pressure-sensitive paint technique based on the heterodyne method was proposed for the precise pressure measurement of unsteady flow fields. This measurement is realized by detecting the beat signal that results from interference between a modulating illumination light source and a pressure fluctuation. The beat signal is captured by a ...
Plotnikow Gustavo A GA Respiratory Care Services, Clínica Basilea, Argentina ; Intensive Care Unit, Sanatorio Anchorena, Buenos Aires, - - 2013
Most of the studies referring cuff tubes' issues were conducted on intubated patients. Not much is known about the cuff pressure performance in chronically tracheostomized patients disconnected from mechanical ventilation. To evaluate cuff pressure (CP) variation in tracheostomized, spontaneously breathing patients in a weaning rehabilitation center. Experimental setup to test ...
White-Traut Rosemary R Department of Women, Children and Family Health Science, College of Nursing, University of Illinois at Chicago, IL 60612, United States. - - 2013
The Medoff-Cooper Nutritive Sucking Apparatus (M-CNSA) has been used to objectively measure sucking maturation in preterm infants. The M-CNSA is able to accurately detect sucking pressures less than 20mmHg, however lower pressure thresholds have not previously been used in research. To determine if differences are observed in the number of ...
Agatz Annika - - 2013
A population experiment with Daphnia magna tested the hypothesis that short-term feeding inhibition provokes a shift in population structure that will vary with conspecific pressure (e.g., pressure occurring from individuals of the same species due to competition for food and space) and increases population sensitivity to a xenobiotic exposure due ...
Gu Dongfeng - - 2013
Blood pressure responses to dietary sodium and potassium interventions vary among individuals. We studied the long-term reproducibility of blood pressure responses to dietary sodium and potassium intake. We repeated the dietary sodium and potassium interventions among 487 Chinese adults 4.5 years after the original dietary intervention. The identical dietary intervention ...
Tsai Chen-Chih - - 2013
We developed a novel technique enabling determination of the permeability of electrospun yarns composed of hundreds of fibers. Analyzing the wicking kinetics in a yarn-in-a-tube composite conduit it was found that the kinetic is very specific. The liquid was pulled by the capillary pressure associated with the meniscus in the ...
Lau A Cw - - 2013
OBJECTIVES. To compare three endotracheal tubes for leakage across the cuff (microaspiration) under a comprehensive set of simulated clinical situations. These were the Mallinckrodt TaperGuard (Covidien, US) with a tapered polyvinyl chloride cuff; the KimVent Microcuff (Kimberly-Clark Health Care, US) with a cylindrical polyurethane cuff, and a conventional Portex (Smiths ...
Enflo Laura - - 2013
Resonance tube phonation in water (RTPW) or in air is a voice therapy method successfully used for treatment of several voice pathologies. Its effect on the voice has not been thoroughly studied. This investigation analyzes the effects of RTPW on collision and phonation threshold pressures (CTP and PTP), the lowest ...
Sashida Yasunori - - 2013
Abstract Management of a chest tube, especially when lasting for a long period, becomes difficult. The orifice of thoracostomy where a tube is inserted is maintained sterile usually with water-tight sutures. The longer and tighter the sutures are placed, the more severely skin becomes sore by pressure. Recently not only ...
Rosado-Reyes Claudette M - - 2013
Rate coefficients for the dehydration of isobutanol have been determined experimentally from comparative rate single pulse shock tube measurements and calculated via multi-structural transition state theory (MS-TST). They are represented by the Arrhenius expression, k(isobutanol → isobutene + H2O)experimental = 7.2×1013 exp(-35 300 K/T) s-1 The theoretical work leads to ...
Barrett Elizabeth J - - 2013
OBJECTIVE: To determine the effect of gastric distension on intraabdominal pressures (IAP) measured directly from the intraperitoneal space. DESIGN: Prospective, experimental study. SETTING: A university-based equine research facility. ANIMALS: Ten healthy adult horses, 5 males and 5 females. INTERVENTIONS: Intraabdominal pressures were measured through an intraperitoneal cannula zeroed at a ...
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