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Spentzas Thomas - - 2010
To determine whether there was a correlation between tonometric measurements of the intraocular pressure and transducer measurements of the intracranial pressure in the acute setting, and whether intraocular pressure can be used as a surrogate measure of intracranial pressure. Children with traumatic brain injuries commonly develop increased intracranial pressure requiring ...
Eide Per Kristian - - 2010
In this study, the authors compare simultaneous measurements of static and pulsatile pressure parameters in the epidural space and brain parenchyma of hydrocephalic patients. Simultaneous intracranial pressure (ICP) signals from the epidural space (ICPEPI) and the brain parenchyma (ICPPAR) were compared in 12 patients undergoing continuous ICP monitoring as part ...
Toma Ahmed K - - 2010
Managing symptomatic ventriculoperitoneal shunts with no clear evidence of shunt malfunction either clinically or radiologically can be a difficult task. The aim of this study was to assess intracranial pressure (ICP) monitoring as a method of investigating shunt function. The authors performed a retrospective analysis of 38 continuous ICP monitoring ...
Lai Hung-Yi - - 2012
The intracranial pressure (ICP) is usually continuously monitored in the management of patients with increased ICP. The aim of this study was to discover a mathematic equation to express the intracranial pressure-volume (P-V) curve and a single indicator to reflect the status of the curve. Patients with severe brain damage ...
Weerakkody Ruwan A RA University of Cambridge, Addenbrooke's Hospital, UK. - - 2010
Increased slow-wave activity in intracranial pressure (ICP) signifies an exhausted cerebrospinal compensatory reserve across a range of conditions. In this study, we attempted to describe synchronisation between slow waves of ICP and of near-infrared spectroscopy (NIRS) variables during controlled elevation of ICP. Nineteen patients presenting with symptomatic hydrocephalus underwent a ...
Li Lucia M LM Academic Neurosurgery Unit, University of Cambridge/Addenbrooks Hospital, Cambridge, CB2 0QH, - - 2010
Increased intracranial pressure occurring after severe traumatic brain injury is a common and potentially devastating phenomenon. It has been clearly demonstrated that increased intracranial pressure that is refractory to initial medical measures is a poor prognostic sign. Current optimal management is based on a sequential, target-driven approach combining both medical ...
Bjerring Peter Nissen - - 2010
The pathogenesis of cerebral edema in acute liver failure is suggested, in in vitro and animal studies, to involve a compromised oxidative metabolism with a decrease in cerebral ATP levels and an increase in purine concentrations. In this study we hypothesize that the cerebral concentrations of hypoxanthine, inosine, and lactate/pyruvate ...
Bourdeaux Chris - - 2010
BACKGROUND: Hypertonic saline is routinely used to treat rises in intracranial pressure (ICP) post-traumatic head injury. Repeated doses often cause a hyperchloremic metabolic acidosis. We investigated the efficacy of 8.4% sodium bicarbonate as an alternative method of lowering ICP without generating a metabolic acidosis. METHODS: We prospectively studied 10 episodes ...
Al-Khawlani A - - 2010
A cross-sectional survey in Sana'a city, Yemen, aimed to determine the prevalence of preventable macrovascular complications and their association with glycaemic control and other risk factors in patients with type 2 diabetes mellitus (DM). Some features of macrovascular disease were found in 79 (25.4%) of the 311 patients: 17.8% had ...
Wendell Linda C - - 2010
BACKGROUND: Ornithine transcarbamylase deficiency (OTCD) is the most common of the urea cycle disorders and results in an accumulation of ammonia and its metabolites. Excess ammonia in the brain is metabolized to glutamine, which increases intracellular osmolarity and contributes to cytotoxic edema. METHODS: We report a case of a woman ...
Cerqueira-Neto Manoel Luiz de - - 2010
To observe the repercussion of respiratory physiotherapy techniques on the mean arterial pressure (MBP), intracranial pressure (ICP), cerebral perfusion pressure (CPP), jugular venous oxygen pressure (PjvO2) and jugular venous oxygen saturation (SjvO2). The sample consisted of 20 patients with head trauma. The protocol consisted of physiotherapy techniques application of vibrocompression ...
Bijlenga Philippe P Academic Neurosurgical Unit, Department of Neurosurgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, CB2 0QQ, - - 2010
Cerebrovascular pressure reactivity depends on cerebral perfusion pressure (CPP), with the optimal CPP (CPPopt) defined as pressure at which cerebrovascular reactivity is functioning optimally, reaching minimal value of pressure reactivity index (PRx). The study investigates the association between vasospasm, PRx, and CPPopt in poor grade patients (WFNS 4&5) after subarachnoid ...
Wall Michael M Department of Neurology, College of Medicine, University of Iowa, Veterans Administration Medical Center, Iowa City, IA 52242, USA. - - 2010
Idiopathic intracranial hypertension ((IIH) is characterized by increased cerebrospinal fluid pressure of unknown cause. It is predominantly a disease of women in the childbearing years. Although the cause of IIH remains obscure, it has become clear that loss of visual function is common and patients may progress to blindness if ...
Kasprowicz M M Addenbrooke's Hospital, Cambridge, UK. - - 2010
A pressure reactivity index (PRx) can be assessed in patients with continuous monitoring of arterial blood pressure (ABP) and intracranial pressure (ICP) as a moving correlation coefficient between slow fluctuations of these two signals within a low frequency bandwidth. The study aimed to investigate whether the invasive ABP monitoring can ...
Marbacher Serge - - 2010
The achieved degree of delayed cerebral vasospasm (DCVS) in the rabbits most frequently applied cistern magna blood injection model is often mild. The aim of this study was to characterize and evaluate the feasibility of an experimental SAH technique that mimics pathophysiological mechanisms and triggers higher degrees of DCVS. SAH ...
Goffar Stephen L - - 2010
PURPOSE/HYPOTHESIS: Lower extremity overuse injuries are a detriment to military readiness. Extreme values of arch height and heavy loads carried by military personnel are associated with an increased risk of overuse injuries. Little is known regarding the impact of load carriage on plantar pressure distributions. This study was conducted to ...
Kapoor Kapil G - - 2010
Idiopathic intracranial hypertension (IIH) is a disease of unknown etiology associated with increased intracranial pressure, predominantly affecting obese females of childbearing age. The history of IIH is quite unique, featuring only limited advancements in evidenced-based treatments, but boasting literally countless changes in nomenclature, proposed etiology, and conceptual approach. Despite its ...
Yaka E - - 2010
We present a 58-year-old man with neurological manifestations indicating increased intracranial pressure in association with hyperthyroidism. Hyperthyroidism due to a hyperfunctioning solitary thyroid nodule was the underlying cause, since all the symptoms disappeared after the treatment of hyperthyroidism. Our aim is to emphasize that hyperthyroidism should be suspected in a ...
Kahraman Sibel - - 2010
BACKGROUND: Earlier, more accurate assessment of secondary brain injury is essential in management of patients with traumatic brain injury (TBI). We assessed the accuracy and utility of high-resolution automated intracranial pressure (ICP) and cerebral perfusion pressure (CPP) recording and their analysis in patients with severe TBI. METHODS: ICP and CPP ...
Salvador Lydia - - 2010
BACKGROUND: During neuroendoscopic procedures, pressure inside the neuroendoscope (PIN) monitored through the irrigation channel correlates with the occurrence of postoperative complications. Our aim was to analyze the reliability of PIN measurement as a surrogate for intracranial pressure (ICP) by comparing PIN with simultaneously epidural ICP measurement as the standard. METHODS: ...
Zuluaga Maria T - - 2010
To describe cerebral regional oxygen saturation measured by near infrared spectroscopy in the setting of normal and increased intracranial pressure in children to evaluate the association between cerebral regional oxygen saturation and intracranial pressure in comparison with other clinical variables. Prospective observational cohort study. Two academic tertiary care centers' pediatric ...
Brady Ken M KM Department of Anesthesiology, Division of Pediatric Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, 600 North Wolfe St., Blalock 943, Baltimore, MD 21287, USA. - - 2010
Cerebrovascular autoregulation monitoring is often desirable for critically ill patients in whom intracranial pressure (ICP) is not measured directly. Without ICP, arterial blood pressure (ABP) is a substitute for cerebral perfusion pressure (CPP) to gauge the constraint of cerebral blood flow across pressure changes. We compared the use of ABP ...
Knudsen Søren Tang - - 2010
Diabetic vascular complications constitute leading causes of blindness, renal failure, and cardiovascular morbidity and mortality world-wide. We studied haemodynamic and structural abnormalities associated with the development of microvascular complications and evaluated the effect of intervention with antihypertensive agents on these risk factors and complications in type 2 diabetic patients (T2DM). ...
Behrens Anders - - 2010
Transcranial Doppler sonography (TCD) assessment of intracranial blood flow velocity has been suggested to accurately determine intracranial pressure (ICP). We attempted to validate this method in patients with communicating cerebrospinal fluid systems using predetermined pressure levels. Ten patients underwent a lumbar infusion test, applying 4 to 5 preset ICP levels. ...
Nichols S D - - 2010
High blood pressure and diabetes mellitus account for over 50% of annual visits to health facilities in Trinidad and Tobago. This study investigates the ability of various absolute and relative body composition variables to predict elevated fasting blood sugar (FBS) and blood pressure (BP). Participants had overnight fasting finger-stick blood ...
Dash Pramod K - - 2010
High intracranial pressure (ICP) is a prominent secondary pathology after traumatic brain injury (TBI) and is a major contributor to morbidity and mortality. Currently, there are no clinically proven methods for predicting which TBI patients will develop high ICP. In the present study, we examined whether the serum levels of ...
Weiner Gregory M - - 2010
Increased intracranial pressure (ICP) can cause brain ischemia and compromised brain oxygen (PbtO2 < or = 20 mm Hg) after severe traumatic brain injury (TBI). We examined whether decompressive craniectomy (DC) to treat elevated ICP reduces the cumulative ischemic burden (CIB) of the brain and therapeutic intensity level (TIL). Ten ...
Hu Xiao X Neural Systems and Dynamics Laboratory, Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, - - 2010
Interventions of intracranial pressure (ICP) elevation in neurocritical care is currently delivered only after healthcare professionals notice sustained and significant mean ICP elevation. This paper uses the morphological clustering and analysis of ICP (MOCAIP) algorithm to derive 24 metrics characterizing morphology of ICP pulses and test the hypothesis that preintracranial ...
Beseoglu K - - 2010
Several recent investigations have demonstrated a significant influence of blood pressure variation during the immediate period after stroke. The present study was conducted to evaluate the effect of blood pressure, intracranial pressure and cerebral perfusion pressure variation on short-term outcome in patients after severe subarachnoid hemorrhage (SAH). 105 patients suffering ...
Brandi Giovanna - - 2010
OBJECTIVE: Assess optimal equation to noninvasively estimate intracranial pressure (eICP) and cerebral perfusion pressure (eCPP) following severe traumatic brain injury (TBI) using transcranial color-coded duplex sonography (TCCDS). DESIGN AND SETTING: This is an observational clinical study in a university hospital. PATIENTS: A total of 45 continuously sedated (BIS < 50), ...
Khan Manzurul Haque - - 2010
This cross-sectional study was carried out to assess and compare Ankle Brachial Systolic Pressure Index (ABSPI) amongst 120 arsenic exposed and 120 non-exposed populations of Samta village in Bangladesh. Abnormal ABSPI was more prevalent in arsenic exposed (13.3%) than in non-exposed (2.5%) group. The prevalence of abnormal ABSPI for respondents ...
Maloney-Wilensky Eileen - - 2010
Secondary neuronal injury is implicated in poor outcome after acute neurological insults. Outcome can be improved with protocol-driven therapy. These therapies have largely been based on monitoring and control of intracranial pressure and the maintenance of an adequate cerebral perfusion pressure. In recent years, brain tissue oxygen partial pressure (PbtO2) ...
Padayachy Llewellyn C - - 2010
Intracranial pressure (ICP) has become a cornerstone of care in adult and pediatric patients with traumatic brain injury (TBI). Despite the fact that continuous monitoring of ICP in TBI was described almost 60 years ago, there are no randomized trials confirming the benefit of ICP monitoring and treatment in TBI. ...
Fan Jun-Yu JY Department of Nursing, Chang Gung Institute of Technology and Chang Gung Medical Foundation, Linkou Branch, 261 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan, Taiwan. - - 2010
Nurses caring for traumatic brain injury (TBI) patients with intracranial hypertension (ICH) recognize that patients whose intracranial adaptive capacity is reduced are susceptible to periods of disproportionate increase in intracranial pressure (DIICP) in response to a variety of stimuli. It is possible that DIICP signals potential secondary brain damage due ...
Elliott Justine J Department of Neuroanaesthesia and Neurocritical Care, The National Hospital for Neurology and Neurosurgery, University College London Hospitals, London, - - 2010
Intracerebral hemorrhage (ICH) is a devastating disease with high rates of mortality and morbidity. The major risk factors for ICH include chronic arterial hypertension and oral anticoagulation. After the initial hemorrhage, hematoma expansion and perihematoma edema result in secondary brain damage and worsened outcome. A rapid onset of focal neurological ...
Walter Bernd - - 2010
OBJECTIVE: There is still a lack of knowledge on the age-dependent relation between a reduction in cerebral perfusion pressure (CPP) and compromised brain perfusion leading to excessive transmitter release and brain damage cascades. The hypothesis is that an age-dependent lower threshold of cerebral blood flow (CBF) autoregulation determines the amount ...
Armstead William M WM Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA 19104, USA. - - 2010
Traumatic brain injury (TBI) is a leading cause of morbidity in children and boys are disproportionately represented. Hypotension is common and worsens outcome after TBI. Previous studies show that adrenomedullin, a cerebrovasodilator, prevented sex dependent impairment of autoregulation during hypotension after piglet fluid percussion brain injury (FPI). We hypothesized that ...
Beri Sushil - - 2011
Familial occurrence of Idiopathic intracranial hypertension has been rarely reported in the literature. Idiopathic intracranial hypertension, both with and without papilloedema is only described in two families before, though one had a probable diagnosis. We report a family of mother and her two daughters. A 37 year old woman was ...
Strydom M A - - 2010
Obstruction of the intracranial dural venous sinuses would result in an increase in intracranial dural venous pressure. This intracranial hypertension is not only the result of poor cerebral venous drainage but also life threatening. The aim of this study was to identify the structures, which may show signs of potential ...
Berdahl John P - - 2010
PURPOSE OF REVIEW: Glaucoma remains a disease with an unclear basic pathophysiology. The optic nerve travels through two pressurized regions: the intraocular space and the intracranial space. Some authors have suggested that the relationship between intraocular pressure and intracranial pressure may play a fundamental role in the development of glaucoma. ...
Mourad Pierre D - - 2010
Brains subjected to blast from an explosive or other sources of trauma often develop intracranial hemorrhage or edema or loose their ability to autoregulate the blood flowing into the brain (cerebral autoregulation). Such damage can, in turn, lead to increases in intracranial pressure (ICP) and decreases in cerebral perfusion pressure ...
Rabinstein Alejandro A - - 2010
Cerebral edema is very common in patients with acute liver failure and encephalopathy. In severe cases, it produces brain tissue shift and potentially fatal herniation. Brain swelling in acute liver failure is produced by a combination of cytotoxic (cellular) and vasogenic edema. Accumulation of ammonia and glutamine leads to disturbances ...
Eide Per K PK Department of Neurosurgery, Rikshospitalet University Hospital, Oslo, Norway. - - 2010
In the search for optimal monitoring and predictive tools in neurocritical care, the relationship of the pulsatile component of intracranial pressure (ICP) and the pressure itself has long been of great interest. Higher pressure often correlates with a higher pulsatile response to the heartbeat, interpreted as a type of compliance ...
De Simone Roberto - - 2010
The association of chronic migraine (CM) with an idiopathic intracranial hypertension without papilledema (IIHWOP), although much more prevalent than expected in clinical series of CM sufferers, is not included among the risk factors for migraine progression. We discuss the available evidence supporting the existence of a pathogenetic link between CM ...
Hallaert Giorgio G - - 2010
Intracranial dural arteriovenous fistulas constitute a rare though potentially devastating disease. Because the arterial (high-pressure) blood flow drains directly into the low-pressure venous system, there is a high risk of bleeding and associated neurological deficit. The classifications by Borden and Cognard underline the correlation between bleeding risk and venous drainage ...
Eide Per Kristian - - 2010
PURPOSE: In patients with idiopathic normal pressure hydrocephalus (iNPH) and ventriculomegaly, examine whether there is a gradient in pulsatile intracranial pressure (ICP) from within the cerebrospinal fluid (CSF) of cerebral ventricles (ICP(IV)) to the subdural (ICP(SD)) compartment. We hypothesized that pulsatile ICP is higher within the ventricular CSF. METHODS: The ...
Eide Per K - - 2010
OBJECT: This study was performed in patients with idiopathic normal-pressure hydrocephalus (iNPH) to monitor cerebral metabolism with microdialysis (MD) and intracranial pressure (ICP) readings, and relate to the clinical responses to extended lumbar drainage (ELD) and shunt surgery. METHODS: The baseline levels of MD metabolites and ICP were monitored overnight ...
Malloy Kelly A - - 2010
BACKGROUND: An abduction deficit or cranial nerve VI palsy can have many potential etiologies. However, a cranial nerve VI palsy in the setting of disc edema suggests increased intracranial pressure, requiring emergent work-up. CASE REPORT: An 18-year-old woman presented with significant headaches and horizontal diplopia, which she claimed began after ...
Oddo Mauro - - 2010
BACKGROUND: We analyzed the impact of shivering on brain tissue oxygenation (PbtO(2)) during induced normothermia in patients with severe brain injury. METHODS: We studied patients with severe brain injury who developed shivering during induced normothermia. Induced normothermia was applied to treat refractory fever (body temperature [BT] > or =38.3 degrees ...
Bao Ying-Hui - - 2010
In this study, we explored the effect of moderate hypothermia on brain tissue oxygenation following acute intracranial hypertension in micropigs. Twenty healthy juvenile micropigs weighting 4-6 kg were randomized into two groups: a normothermia group (n = 10) and a moderate hypothermia group (n = 10). The animals were intravenously ...
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