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Giorgino Francesco - - 2011
Type 2 diabetes mellitus (T2DM) is increasing in prevalence at alarming rates. Concurrent with the its expanding prevalence, is the increase in the related risk of morbidity and mortality. Because diabetic patients are prone to cardiovascular disease, treatment strategies should address the cardiovascular risk factors, including blood pressure, lipids, and ...
Sugiura Yoshimi - - 2011
PURPOSE:: To measure ophthalmodynamometric pressure (ODP) during vitrectomy in patients with proliferative diabetic retinopathy (PDR). DESIGN:: Prospective, interventional, consecutive case series. METHODS:: This study included 75 eyes of 75 patients undergoing vitrectomy for PDR. After core vitrectomy, the intraocular pressure was gradually raised using a vented-gas forced-infusion system (VGFI), and ...
Ushigome Emi - - 2011
The purposes of this study were to investigate the state of blood pressure control level and to investigate the relationship between blood pressure control level and nephropathy in Japanese type 2 diabetes. We measured clinic and home blood pressure in 923 type 2 diabetic patients. According to the criteria for ...
Thoenes Martin - - 2011
BACKGROUND: In Germany, an estimated 20-25 million patients suffer from hypertension. Blood pressure control rates are, however, lower than in many other European countries and the USA. The present analysis reports blood pressure treatment and control rates in Germany in patients with hypertension treated by cardiologists. METHODS: The present analysis ...
Fiedler Karin Elisabeth - - 2011
AIMS: A proof of concept study to investigate the effect of shoe lacing on the plantar pressure distribution and in-shoe displacement of the foot during walking. METHODS: Three randomized shoe-lacing conditions, which differed in lacing tightness (comfortable, loosened, and completely loose) were investigated in 20 healthy adults. On a 10-m ...
McAdam-Marx Carrie - - 2011
This cross-sectional study describes glycemic, body mass, and blood pressure (BP) control in patients with type 2 diabetes mellitus (T2DM) in an ambulatory care-based database of electronic medical records (EMRs). Patients aged ≥18 years with T2DM documented in 2008 and with glycosylated hemoglobin (HbA(1c)) value, body mass index (BMI), and ...
Jungner Mårten - - 2011
To compare the intracranial pressure after resuscitation to normovolemia by using 20% albumin or normal saline in a cat model of meningitis. Prospective, randomized animal study. University hospital laboratory. Twenty adult, male cats. Meningitis was induced by intrathecal injection of Escherichia coli-derived lipopolysaccharide (0.8 × 10 units/kg). Four hours after ...
Ogawa Susumu - - 2011
Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, is a newly developed oral hypoglycemic agent. Sitagliptin increases the level of glucagon-like polypeptide (GLP)-1 that increases insulin secretion. In addition, GLP-1 decreases salt intake and increases urinary salt excretion. Therefore, the sitagliptin treatment might lower blood pressure in hypertensive patients with type 2 ...
Kawamoto Ryuichi - - 2011
Adiponectin is one of the important molecules in the development of metabolic syndrome, and its concentration is decreased in obesity, type-2 diabetes, and cardiovascular disease. We aim to determine whether serum high-molecular weight (HMW) adiponectin, which is thought to represent the biological active form, was associated with a risk for ...
Salinero-Fort Miguel A - - 2011
Individual health education is considered to be essential in the overall care of patients with type 2 diabetes (DM2), although there is some uncertainty regarding its metabolic control benefits. There have been very few randomized studies on the effects of individual education on normal care in DM2 patients with a ...
Garcia-Ortiz Luis L Unidad de Investigación de Atención Primaria La Alamedilla, Salamanca, Spain. - - 2011
Ambulatory blood pressure monitoring (ABPM) shows a better correlation to target organ damage and cardiovascular morbidity-mortality than office blood pressure. A loss of arterial elasticity and an increase in carotid artery intima-media thickness (IMT) has been associated with increased cardiovascular morbidity-mortality. Tools have been developed that allow estimation of the ...
Stolwijk Niki M NM Sint Maartenskliniek, Research Development and Education, Hengstdal 3, 6522 JV Nijmegen, P.O. Box 9011 6500 GM, The Netherlands. - - 2011
Although many patients with foot complaints receive customized insoles, the choice for an insole design can vary largely among foot experts. To investigate the variety of insole designs used in daily practice, the insole design and its effect on plantar pressure distribution were investigated in a large group of patients. ...
Martin Catherine A - - 2010
BACKGROUND: Isolated clinic hypertension (ICHT) may be an indicator of both future hypertension and diabetes. This study examines the 2-h plasma glucose level post load (2hPG), and measures of arterial stiffness, autonomic function and circulating biomarkers in ICHT, normotension and hypertension. METHODS: Participants aged 39-75 years, who were untreated for ...
Jang Ji Hwan - - 2011
The factors related to death and functional recovery after primary pontine hemorrhage (PPH) in Koreans has not been well defined. The authors sought to identify independent predictors of death and functional recovery after PPH using data obtained at a single institute. Data were collected retrospectively on 281 patients with PPH ...
Shatat Ibrahim F - - 2010
Renin-angiotensin system (RAS) activation and abnormalities of ambulatory blood pressure (ABP) are present in obesity, but relationships between components of the RAS and ABP have not been defined in the young. Anthropometric measurements and 24-h ABP were obtained on 30 obese adolescents with and without type 2 diabetes. Plasma renin ...
Siegel David - - 2010
Abstract The Action to Control Cardiovascular Risks in Diabetes Study (ACCORD) was a well-designed trial of 10,251 patients with type 2 diabetes mellitus that studied the effects of tight control of blood sugar, hypertension, and lipids. Disappointingly, as compared with standard treatment, the use of intensive therapy to target normal ...
Ter Chao Chia- - - 2010
A 78-year-old man with hypertension and diabetes mellitus was brought to the emergency department having suffered fever and disturbances in consciousness for 2 days. On examination, his vital signs were as follows: body temperature 38°C, heart rate 116 beats/minute, respiratory rate 22/ minute, and blood pressure 145/72 mmHg. Abdominal examinations ...
Wilborn Doris - - 2010
The objective of this study was to describe the relationship between the German National Expert Standard Pressure Ulcer Prevention and the pressure ulcer prevalence in German nursing homes and hospitals. The patient outcome pressure ulcer does not only depend on individual characteristics of patients, but also on institutional factors. In ...
Kanoun Faouzi - - 2010
Background: Good blood pressure control is one of the recommended targets in diabetic patient's management. Aim: To evaluate blood pressure (BP) control in hypertensive treated diabetic patients using ambulatory blood pressure measurement (ABPM). Methods: Two hundred and six hypertensive treated diabetic patients were enrolled in this study (83 men and ...
Friedman Deborah I - - 2010
Neuro-ophthalmologists frequently care for patients with idiopathic intracranial hypertension (IIH), although many questions remain unanswered regarding its diagnosis, pathogenesis, and treatment. The Friedman-Jacobson criteria for the diagnosis of IIH specify lumbar puncture (LP) opening pressure values that are largely based on experience with little supporting normative data. Until recently, there ...
Huang Gui - - 2010
The value of the left atrial volume tracking (LAVT) method in the evaluation of left atrial (LA) function in patients with diabetes mellitus (DM) was examined in this study. Fifty-eight DM patients as DM group and 40 healthy people as normal control group were enrolled in this study. EUB-6500 echocardiographic ...
Ishii Yukihito - - 2011
Blood pressure in female SDT-fa/fa rats was periodically investigated at ages 8, 16, and 24 weeks. Furthermore, an insulin therapy was performed for 5 weeks in the female rats at age 11 weeks, and the change of blood pressure was examined. In addition to obesity, hyperglycemia, hyperinsulinemia, and hyperlipidemia, hyperleptinemia ...
Pau Massimiliano - - 2010
Although the scientific community widely recognizes that backpack carriage in primary school children represents a critical issue, its consequences in terms of postural alterations and possible onset of musculoskeletal pathologies are still not fully understood. In particular, little information is available on the way load carriage modifies the foot-ground relationship ...
Shatoor Abdullah S - - 2011
A cross-sectional stratified sample of 1249 adolescent secondary school boys was studied. More than 25% of boys did not practice any physical exercise. More than half of the parents (54.5%) were consanguineous. High prevalence of parental history of hypertension, diabetes and high blood lipids was found. Smoking amounted to 11.8%. ...
Javorka Michal - - 2010
The aim of our study was to employ novel nonlinear synchronization approaches as a tool to detect baroreflex impairment in young patients with subclinical autonomic dysfunction in Type 1 diabetes mellitus (DM) and compare them to standard linear baroreflex sensitivity (BRS) methods. We recorded beat-to-beat pulse interval (PI) and systolic ...
Bordes J - - 2011
Bacterial meningitis remains a life-threatening disease mainly due to intracranial hypertension. However, decompressive craniectomy (DC) and the use of cerebral microdialysis (MD) and brain tissue oxygen pressure measurement (pTiO(2) ) are poorly described in this disease. We report a case of a 56-year-old woman admitted for severe bacterial meningitis complicating ...
Gatson J W - - 2011
After traumatic brain injury (TBI), a progressive injury and death of neurons and glia leads to decreased brain function. Endogenous and exogenous estrogens may protect these vulnerable cells. In this study, we hypothesized that increased pressure leads to an increase in aromatase expression and estrogen production in astrocytes. In this ...
Yuh Esther L - - 2010
Intracranial pressure (ICP) is the pressure within the intracranial space. Intracranial hypotension is a clinical syndrome in which low cerebrospinal fluid volume (CSF) results in orthostatic headache. Severe cases can result in nausea, vomiting, photophobia, and, rarely, decreased level of consciousness and coma. CSF opening pressure can be within the ...
Zweifel Christian C Academic Neurosurgical Unit, University of Cambridge Clinical School, Cambridge, United Kingdom. - - 2010
Monitoring of cerebrovascular pressure reactivity (PRx) has diagnostic and prognostic value in head-injured patients, but requires invasive monitoring of intracranial pressure (ICP). Near infrared spectroscopy (NIRS) is a noninvasive method that is suitable for continuous detection of cerebral blood volume changes. We compared a NIRS-based index of cerebrovascular reactivity, called ...
Tzoufi Meropi - - 2010
We present the case of an 11-year-old obese girl who presented with idiopathic intracranial hypertension affecting first the lateral abducens nerve. She received acetazolamide, but 5 days later she developed lateral, peripheral facial palsy. Imaging evaluation was normal, which primarily excluded cerebral venous thrombosis and sustained the initial diagnosis. Despite ...
Kubota Hiroshi - - 2010
Brain protection is important during aortic arch surgery, especially in patients with cerebral ischemia. We clinically applied the effectiveness of a novel protocol of retrograde cerebral perfusion with intermittent pressure augmentation for brain protection in a canine model, as described in a previous report. Although, in our patient the brachiocephalic ...
Fàbregas Neus - - 2010
Endoscopic neurosurgical procedures are becoming more frequent and popular in the treatment of intracranial disease. When endoscopy involves the intraventricular structures, irrigating solutions are required and may contribute to sudden and sharp increases in intracranial pressure. More recently, nasal endoscopic approach has been used to perform skull base surgery for ...
Toma Ahmed K - - 2010
Investigating pseudotumour cerebri (PTC) patients who do not fulfil the diagnostic criteria, or those presenting post-shunt insertion with recurrent symptoms and signs, with no clear evidence of shunt malfunction, present a diagnostic challenge. PTC patients who underwent continuous intracranial pressure (ICP) monitoring in our unit were reviewed retrospectively. Twenty-six ICP ...
Helbok Raimund - - 2011
Background The impact of osmotic therapies on brain metabolism has not been extensively studied in humans. The authors examined if mannitol treatment of raised intracranial pressure will result in an improvement in brain metabolism together with the expected drop in intracranial pressure (ICP). Methods This is a retrospective review of ...
Skau Maren - - 2011
Idiopathic intracranial hypertension (IIH) is a disorder of raised intracranial pressure (ICP) in the absence of identifiable pathology. The purpose of this study was to evaluate the clinical presentation and monitor a 3-month course using frequent optical coherence tomography (OCT) evaluations, visual field testings and lumbar opening pressure measurements. A ...
Rangel-Castilla Leonardo L Department of Neurosurgery, The Methodist Neurological Institute, The Methodist Hospital, Houston, Texas, - - 2010
The purpose of this study was to examine the effects of hyperventilation or hyperoxia on cerebral hemodynamic parameters over time in patients with severe traumatic brain injury (TBI). We prospectively studied 186 patients with severe TBI. CO₂ and O₂ reactivity tests were conducted twice a day on days 1-5 and ...
Sankhyan Naveen - - 2010
Appropriate management of raised intracranial pressure begins with stabilization of the patient and simultaneous assessment of the level of sensorium and the cause of raised intracranial pressure. Stabilization is initiated with securing the airway, ventilation and circulatory function. The identification of surgically remediable conditions is a priority. Emergent use of ...
Wei Guo - - 2010
Penetrating ballistic brain injury involves a leading shockwave producing a temporary cavity causing substantial secondary injury. In response to the prevalence of this type of brain trauma in the military, a rat model of penetrating ballistic-like brain injury (PBBI) was established. This study focuses on cerebral physiological responses resulting from ...
Spentzas Thomas - - 2010
To determine whether there was a correlation between tonometric measurements of the intraocular pressure and transducer measurements of the intracranial pressure in the acute setting, and whether intraocular pressure can be used as a surrogate measure of intracranial pressure. Children with traumatic brain injuries commonly develop increased intracranial pressure requiring ...
Eide Per Kristian - - 2010
In this study, the authors compare simultaneous measurements of static and pulsatile pressure parameters in the epidural space and brain parenchyma of hydrocephalic patients. Simultaneous intracranial pressure (ICP) signals from the epidural space (ICPEPI) and the brain parenchyma (ICPPAR) were compared in 12 patients undergoing continuous ICP monitoring as part ...
Toma Ahmed K - - 2010
Managing symptomatic ventriculoperitoneal shunts with no clear evidence of shunt malfunction either clinically or radiologically can be a difficult task. The aim of this study was to assess intracranial pressure (ICP) monitoring as a method of investigating shunt function. The authors performed a retrospective analysis of 38 continuous ICP monitoring ...
Lai Hung-Yi - - 2012
The intracranial pressure (ICP) is usually continuously monitored in the management of patients with increased ICP. The aim of this study was to discover a mathematic equation to express the intracranial pressure-volume (P-V) curve and a single indicator to reflect the status of the curve. Patients with severe brain damage ...
Weerakkody Ruwan A RA University of Cambridge, Addenbrooke's Hospital, UK. - - 2010
Increased slow-wave activity in intracranial pressure (ICP) signifies an exhausted cerebrospinal compensatory reserve across a range of conditions. In this study, we attempted to describe synchronisation between slow waves of ICP and of near-infrared spectroscopy (NIRS) variables during controlled elevation of ICP. Nineteen patients presenting with symptomatic hydrocephalus underwent a ...
Li Lucia M LM Academic Neurosurgery Unit, University of Cambridge/Addenbrooks Hospital, Cambridge, CB2 0QH, - - 2010
Increased intracranial pressure occurring after severe traumatic brain injury is a common and potentially devastating phenomenon. It has been clearly demonstrated that increased intracranial pressure that is refractory to initial medical measures is a poor prognostic sign. Current optimal management is based on a sequential, target-driven approach combining both medical ...
Bjerring Peter Nissen - - 2010
The pathogenesis of cerebral edema in acute liver failure is suggested, in in vitro and animal studies, to involve a compromised oxidative metabolism with a decrease in cerebral ATP levels and an increase in purine concentrations. In this study we hypothesize that the cerebral concentrations of hypoxanthine, inosine, and lactate/pyruvate ...
Bourdeaux Chris - - 2010
BACKGROUND: Hypertonic saline is routinely used to treat rises in intracranial pressure (ICP) post-traumatic head injury. Repeated doses often cause a hyperchloremic metabolic acidosis. We investigated the efficacy of 8.4% sodium bicarbonate as an alternative method of lowering ICP without generating a metabolic acidosis. METHODS: We prospectively studied 10 episodes ...
Al-Khawlani A - - 2010
A cross-sectional survey in Sana'a city, Yemen, aimed to determine the prevalence of preventable macrovascular complications and their association with glycaemic control and other risk factors in patients with type 2 diabetes mellitus (DM). Some features of macrovascular disease were found in 79 (25.4%) of the 311 patients: 17.8% had ...
Wendell Linda C - - 2010
BACKGROUND: Ornithine transcarbamylase deficiency (OTCD) is the most common of the urea cycle disorders and results in an accumulation of ammonia and its metabolites. Excess ammonia in the brain is metabolized to glutamine, which increases intracellular osmolarity and contributes to cytotoxic edema. METHODS: We report a case of a woman ...
Cerqueira-Neto Manoel Luiz de - - 2010
To observe the repercussion of respiratory physiotherapy techniques on the mean arterial pressure (MBP), intracranial pressure (ICP), cerebral perfusion pressure (CPP), jugular venous oxygen pressure (PjvO2) and jugular venous oxygen saturation (SjvO2). The sample consisted of 20 patients with head trauma. The protocol consisted of physiotherapy techniques application of vibrocompression ...
Bijlenga Philippe P Academic Neurosurgical Unit, Department of Neurosurgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, CB2 0QQ, - - 2010
Cerebrovascular pressure reactivity depends on cerebral perfusion pressure (CPP), with the optimal CPP (CPPopt) defined as pressure at which cerebrovascular reactivity is functioning optimally, reaching minimal value of pressure reactivity index (PRx). The study investigates the association between vasospasm, PRx, and CPPopt in poor grade patients (WFNS 4&5) after subarachnoid ...
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