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Soul Janet S - - 2007
Cerebral blood flow pressure-passivity results when pressure autoregulation is impaired, or overwhelmed, and is thought to underlie cerebrovascular injury in the premature infant. Earlier bedside observations suggested that transient periods of cerebral pressure-passivity occurred in premature infants. However, these transient events cannot be detected reliably by intermittent static measurements of ...
Prabhakar H - - 2007
Not many centres measure intracranial pressure during an endoscopic procedure. However, if the irrigation fluid during endoscopy is not simultaneously drained, then some rise in intracranial pressure can be anticipated. This study was carried out to measure and monitor changes in intracranial pressure during the irrigation phase in a neuroendoscopic ...
Henzler Dietrich - - 2007
OBJECTIVE: Survival of patients with severe traumatic brain injury may be improved by minimizing secondary brain injury. We aimed to identify potentially modifiable contributors to secondary brain injury that may persist and adversely affect patient outcome. DESIGN: Retrospective case control study. Nonsurviving patients with traumatic brain injury were selected and ...
Prabhakar H - - 2007
BACKGROUND: The Valsalva manoeuvre results in an increase in intrathoracic pressure which alters the systemic and cerebral circulations significantly. We decided to record changes in the intracranial pressure and cerebral perfusion pressure resulting from a Valsalva manoeuvre in anaesthetised patients. METHODS: 11 patients of either gender submitted to surgical neuroendoscopic ...
Rohr A - - 2007
Elevated intracranial intravenous pressure seems to be of importance in pseudotumor cerebri syndromes, either as a cause (secondary intracranial hypertension) or as a consequence (idiopathic intracranial hypertension) of increased intracranial pressure. We present 3 case reports in which diagnostic imaging before and after CSF diversion provided evidence that narrowing of ...
Avitsian Rafi - - 2007
Cerebral vasospasm after subarachnoid hemorrhage can decrease cerebral blood flow with the potential for stroke. Induction of Triple-H therapy (hypertension, hypervolemia, and hemodilution) is an accepted medical therapy to decrease the delayed cerebral ischemia related to vasospasm. Recently selective intra-arterial injection of nicardipine during angiography has also been proposed as ...
McDannold Nathan - - 2007
We have developed a method to use low-intensity focused ultrasound pulses combined with an ultrasound contrast agent to produce temporary blood-brain barrier disruption (BBBD). This method could provide a means for the targeted delivery of drugs or imaging agents into the brain. In all our previous work, we used Optison ...
Eide Per Kristian - - 2008
Simultaneous continuous intracranial pressure (ICP) signals from two different ICP sensors (Codman ICP MicroSensor; Johnson & Johnson, Raynham, MA) placed within the brain parenchyma and the epidural space were compared in ten patients with idiopathic normal pressure hydrocephalus (iNPH). Comparisons were made at the single ICP wave level by determining ...
Kaptigau W Matui - - 2007
Traumatic brain injury (TBI) is one of 3 leading causes of deaths in the Surgery Department of Port Moresby General Hospital in the last 30 years despite being responsible for only 5% of admissions. It maims and kills the young. Most of these injuries and deaths can be prevented by ...
Scalea Thomas M - - 2007
OBJECTIVES: Fluid therapy and/or acute lung injury may increase intra-abdominal pressure (IAP) and intrathoracic pressure, thereby increasing intracranial pressure (ICP) after traumatic brain injury (TBI). Further fluid administration to support cerebral perfusion or increasing ventilatory support to treat acute lung injury further increases ICP. This can create a cycle that ...
Daley Michael L - - 2007
Changes in the modes of cerebrovascular pressure transmission during cerebral vasodilation induced by hypercapnic challenge were examined as a means for developing the basis for a bedside method to evaluate regulation of cerebral blood flow. Recordings of arterial blood pressure (ABP) and intracranial pressure (ICP) obtained from a piglet preparation ...
Kaptigau W Matui - - 2007
Continuous appraisal of clinical indices with appropriate tests and their recording as evidence of treatment are conducive for evidence-based management of traumatic brain injury (TBI). Monitoring of various neurological indices and relating them to set parameters of TBI is imperative for gauging ongoing treatment. These parameters include cerebral oxygenation, cerebral ...
Murakami Mamoru - - 2007
A 19-year-old female was admitted to our hospital after severe head injury in a traffic accident. On admission, she had no spontaneous respiration, but did have heart beat with a blood pressure of 100/60 mmHg. Neurological examination demonstrated that the Glasgow Coma Scale score was 3 and her pupils were ...
Ract Catherine - - 2007
OBJECTIVE: To evaluate the usefulness of early transcranial Doppler ultrasound (TCD) goal-directed therapy after severe traumatic brain injury initiated before invasive cerebral monitoring is available. DESIGN: Prospective, observational clinical study. SETTING: Surgical intensive care unit, university hospital. PATIENTS AND PARTICIPANTS: Twenty-four severely brain-injured patients. INTERVENTIONS: All patients had TCD measurements ...
Aly E E - - 2007
Idiopathic intracranial hypertension is a rare syndrome characterised by prolonged elevation of intracranial pressure in the absence of hydrocephalus, intracranial mass lesion or infection, and with increased cerebrospinal fluid pressure but a normal composition. We report a case of uncontrolled idiopathic intracranial hypertension successfully managed using an intrathecal catheter for ...
Jaeger Matthias - - 2007
BACKGROUND AND PURPOSE: Disturbances of cerebrovascular autoregulation are thought to be involved in delayed cerebral ischemia and infarction after aneurysmal subarachnoid hemorrhage (SAH). We hypothesized that the continuous monitoring of brain tissue oxygen (PtiO(2)) pressure reactivity enables the detection of impaired autoregulation after SAH and that impaired autoregulation is associated ...
Sakowitz Oliver W - - 2007
BACKGROUND: Osmotic agents are widely used to lower elevated intracranial pressure (ICP). However, little data are available regarding cerebral oxygenation and metabolism in the traumatized brains studied under clinical conditions. The present prospective, open-labeled clinical study was designed to investigate whether administration of mannitol, with the aim of reducing moderate ...
Yanagawa Youichi - - 2007
BACKGROUND: Vasospasm caused by intracranial hypertension in head injury remains controversial. METHODS: Between 1996 and 2004, we prospectively and consecutively performed conventional cerebral angiography for six patients with head injuries who showed persistent intracranial hypertension (over 20 mm Hg for longer than 5 days) despite performing various treatments for intracranial ...
Tankisi Alp - - 2007
OBJECT: To the authors' knowledge, repeated measurements of intracranial pressure (ICP), cerebral perfusion pressure (CPP), and the degree of dural tension during different positions on the operating table (reverse Trendelenburg position [rTp]) have not been studied in patients undergoing craniotomy. METHODS: In the present study 53 patients with supratentorial cerebral ...
Lavinio Andrea A Department of Academic Neurosurgery, Box 167, Addenbrooke's Hospital, Cambridge, - - 2007
Mx is an index of cerebrovascular autoregulation. It is calculated as the correlation coefficient between slow spontaneous fluctuations of cerebral perfusion pressure (cerebral perfusion pressure=arterial blood pressure-intracranial pressure) and cerebral blood flow velocity. Mx can be estimated noninvasively (nMxa) with the use of a finger plethysmograph arterial blood pressure measurement ...
Lenfeldt N - - 2007
The accuracy of estimating intracranial pressure in brain tissue (ICP(BT)) via lumbar space was investigated using preset pressure levels in the interval 0 to 600 mm H(2)O in patients with communicating hydrocephalus. Lumbar space ICP correlated excellently to ICP(BT), demonstrated by a measured mean difference of 10 mm H(2)O (0.75 ...
Zanier Elisa Roncati - - 2007
INTRODUCTION: The presence of intracranial hypertension (HICP) after traumatic brain injury (TBI) affects patient outcome. Intracranial pressure (ICP) data from electronic monitoring equipment are usually calculated and recorded hourly in the clinical chart by trained nurses. Little is known, however, about how precisely this method reflects the real patterns of ...
Cormio Manuela - - 2007
INTRODUCTION: Aim of this randomized prospective clinical trial is to compare two methods of antipyretics and evaluate their efficacy in controlling fever during the acute phase of brain damage. METHODS: Twenty-two febrile comatose patients: 12 severe traumatic brain injury and 10 subarachnoid hemorrhage divided in 2 groups: Diclofenac low-dose infusion ...
Czarnik Tomasz - - 2007
BACKGROUND: Some publications suggest a strong correlation between the intracranial pressure and the intraocular pressure. Other studies claim no correlation between these two physiologic variables. Our aim was to study whether the tonometry could be a useful method to evaluate intracranial pressure in patients with suspected intracranial abnormality. METHODS: We ...
Muehlschlegel Susanne - - 2007
INTRODUCTION: Hypertensive, hypervolemic, and hemodilutional (HHH) therapy for vasospasm in subarachnoid hemorrhage (SAH) refractory to phenylephrine requires high doses of catecholamines, leading to adverse adrenergic effects. Arginine vasopressin (AVP) has been shown to stabilize advanced shock states while facilitating reduction of catecholamine doses, but its use has never been reported ...
Natale JoAnne E - - 2007
OBJECTIVE: Magnesium sulfate is neuroprotective in preclinical models, but there are limited safety data regarding its clinical use for pediatric traumatic brain injury. We conducted a pilot study in children with severe traumatic brain injury to a) examine if magnesium sulfate decreases mean arterial pressure, decreases cerebral perfusion pressure, increases ...
Wauters J - - 2007
Elevated intra-abdominal pressure (IAP) exerts effects not only on intra-abdominal organs, but also on organs distant to the abdominal compartment. Abdomino-thoracic interaction during intra-abdominal hypertension (IAH) or abdominal compartment syndrome (ACS) interferes with pulmonary, cardiovascular and cerebral function. In accordance with recent guidelines, IAH is defined as IAP above 12 ...
De laet I - - 2007
INTRODUCTION: Intra-abdominal hypertension (IAH) and abdominal compartment syndrome are a common occurrence in ICU patients. The deleterious effects of IAH on organ function are well known and increasingly appreciated in recent years, especially where renal and respiratory function are concerned. METHODS: This review will focus on the available literature from ...
Agarwal Madhu R - - 2007
Idiopathic intracranial hypertension, also known as pseudotumor cerebri, is a condition of increased intracranial pressure without the presence of mass lesions and with normal cerebrospinal fluid composition. Patients may experience papilledema and vision loss. Optic nerve sheath fenestration (ONSF) is one method of stabilizing visual function and decreasing optic nerve ...
Choi James J - - 2007
The feasibility of blood-brain barrier (BBB) opening in the hippocampus of wild-type mice using focused ultrasound (FUS) through the intact skull and skin was investigated. Needle hydrophone measurements through ex vivo skulls revealed minimal attenuation ( approximately 18% of the pressure amplitude), a well-focused beam pattern and minute focus displacement ...
Furgała Agata - - 2007
Most of the disturbances of autonomic system (AS) activity seen in clinical practice result from head injury are due to development of increased intracranial pressure (ICP). It has been described that cerebral lesions produce hypersympathetic states mediated mostly by sympatho-adrenal discharge. Aim of the study was to evaluate effects of ...
Czosnyka Marek M Academic Neurosurgical Unit, University of Cambridge Clinical School, Cambridge, United Kingdom. MC141@medschl.cam.ac.uk - - 2007
Many doctors involved in the critical care of head-injured patients understand intracranial pressure (ICP) as a number, characterizing the state of the brain pressure-volume relationships. However, the dynamics of ICP, its waveform, and secondarily derived indices portray useful information about brain homeostasis. There is circumstantial evidence that this information can ...
Jetzki S S RWTH Aachen University, Helmholtz-Institute, Chair for Medial Information Technology, 52074 Aachen, Germany. - - 2007
In the therapy of hydrocephalus the dynamic course of the intracranial pressure (ICP) is rarely considered, although it may contain valuable diagnostic information. Several models for intracranial pressure and fluid dynamics are described. Assuming a simplified model and deriving the intracranial pressure wave relationships, this model could be partially confirmed ...
Takahashi T T Dept. of Mechanical Engineering Informatics, Meiji University, Kawasaki, Japan. - - 2007
The purpose of this paper is to discuss the basic study of mechanism of brain injury analytically and experimentally, in respect to the frequency analysis of the pressure changes. First, a three-dimensional FEM model for impact analysis was presented. The pressure changes inside a brain agar phantom and its frequency ...
Zhang Jiangyue - - 2007
Biomechanical quantification of projectile penetration using experimental head models can enhance the understanding of civilian ballistic brain injury and advance treatment. Two of the most commonly used handgun projectiles (25-cal, 275 m/s and 9 mm, 395 m/s) were discharged to spherical head models with gelatin and Sylgard simulants. Four ballistic ...
Yannopoulos Demetris - - 2006
OBJECTIVE: To evaluate the potential to use subatmospheric intrathoracic pressure to regulate intracranial pressure (ICP) in normovolemic and hypovolemic animals, we tested the hypothesis that mechanical devices designed to reduce intrathoracic pressure will decrease ICP in a dose-related manner. An inspiratory impedance threshold device was used in spontaneously breathing animals ...
Geddes J F - - 2006
Unexplained subdural and retinal haemorrhages in an infant are commonly attributed to 'shaking', the mechanism of which is believed to be traumatic venous rupture. However, the haemorrhagic retinopathy reported as a result of Valsalva manoeuvres and the subdural bleeding that is a rare complication of pertussis together demonstrate that if ...
Gondim Jackson A - - 2006
OBJECTIVE: To determine if there was a relationship between intrassellar pressure (ISP) and pituitary tumor volume. METHOD: Between August 2002 and May 2004, 60 patients aged between 13 and 75 years old (39 males), having a pituitary adenoma were submitted to an endoscope transseptal approach. During the surgery and before ...
Lescot Thomas - - 2006
OBJECTIVE: The aim of this study was to quantify the effect of hypertonic saline solution on contused and noncontused brain tissue in patients with traumatic brain injury. We hypothesize that hypertonic saline would increase the volume of brain contusion while decreasing the volume of noncontused hemispheric areas. DESIGN: Prospective observational ...
Eide P K - - 2006
The aim of this study was to explore how the lumbar cerebrospinal fluid pressure (CSFP) waves recorded during lumbar infusion compared with the intracranial pressure (ICP) waves recorded, either during lumbar infusion or during long-term, overnight monitoring. For this purpose, we assessed 27 simultaneous lumbar CSFP/ICP recordings made during lumbar ...
Mitchell Patrick - - 2007
To determine the statistical characteristics of blood pressure (BP) readings from a large number of head-injured patients. The BrainIT group has collected high time-resolution physiological and clinical data from head-injured patients who require intracranial pressure (ICP) monitoring. The statistical features of this dataset of BP measurements with time resolution of ...
Eide P K - - 2006
OBJECT: To relate intracranial pressure (ICP) levels and single ICP wave amplitudes to the acute clinical state (Glasgow Coma Score, GCS) and final clinical outcome (Glasgow Outcome Score, GOS) in patients with subarachnoid haemorrhage (SAH). METHODS: Twenty-seven consecutive patients with severe SAH had their ICP and arterial blood pressure (ABP) ...
Dohmen Christian - - 2007
BACKGROUND AND PURPOSE: To study cerebrovascular autoregulation and its impact on clinical course in patients with impending malignant middle cerebral artery infarction, we used invasive multimodal neuromonitoring, including measurement of cerebral perfusion pressure, tissue oxygen pressure, and microdialysis. METHODS: Fifteen patients with a stroke that involved >50% of the middle ...
Latka, M.
We employ complex continuous wavelet transforms to develop a consistent mathematical framework capable of quantifying both cerebrospinal compensatory reserve and cerebrovascular pressure reactivity. The wavelet gain, defined as the frequency dependent ratio of time averaged wavelet coefficients of intracranial pressure (ICP) and arterial blood pressure (ABP) fluctuations, characterizes the dampening ...
Koźniewska E - - 2006
The main consequence of subarachnoid hemorrhage, for those who survive bleeding, is delayed, persistent vasospasm of intracranial conduit arteries which occurs between the third and seventh day after the insult and results in symptomatic brain ischemia in about 40% of cases. This vasospasm is considered to be a major cause ...
Enam Syed Ather - - 2006
Cerebral venous sinus thrombosis (CVST) usually is taken care of by medical management or neuro-interventional vascular techniques. Some cases of CVST may take a malignant course if the intracranial pressure increases excessively. This increase in pressure is because of oedema in brain tissue due to impediment in venous return and/or ...
Fodstad Harald - - 2006
Increasing systolic and pulse pressure with bradycardia and respiratory irregularity are signs of increased intracranial pressure, leading to cerebral herniation and fatal brainstem compression. This phenomenon, the vasopressor response, is generally known as the Cushing reflex based on Harvey Cushing's experimental work in Europe in 1901 and 1902. However, similar ...
Kirkness Catherine J - - 2006
BACKGROUND: Clinical bedside monitoring systems do not provide prominent displays of data on cerebral perfusion pressure (CPP). Immediate visual feedback would allow more rapid intervention to prevent or minimize suboptimal pressures. OBJECTIVE: To evaluate the effect of a highly visible CPP display on immediate and long-term functional outcome in patients ...
Splavski Bruno - - 2006
PRIMARY OBJECTIVE: To investigate the potential of transcranial Doppler ultrasonography in estimating post-traumatic intra-cranial pressure early after severe traumatic brain injury. RESEARCH DESIGN: The group of 24 patients was analysed for the observation of an early post-traumatic cerebral haemodynamic by middle cerebral artery blood velocity measuring. METHODS AND PROCEDURES: The ...
Foss Tonje - - 2007
BACKGROUND/AIMS: Previous research has shown improvements in the clinical triad (gait, incontinence and cognitive dysfunction) after shunt surgery in idiopathic normal pressure hydrocephalus (iNPH) patients with intracranial pulse pressure amplitudes >4-5 mm Hg, the pulse amplitudes being <4 mm Hg in the nonresponders. However, it is unknown whether similar differences ...
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