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Steier Joerg J King's College London School of Medicine, King's Health Partners, King's College Hospital, , London, - - 2014
Severe obesity causes respiratory morbidity and mortality. The impact of obesity on the mechanics of breathing is not fully understood. We undertook a comprehensive observational study of lung volumes and elasticity in nine obese and nine normal weight subjects, seated and supine, during spontaneous breathing. Seated and supine total lung ...
Pirozzi Kelly K Chief Resident, Temple University Hospital Podiatric Surgical Residency Program, Temple University Hospital, Philadelphia, - - 2014
An increasing body of evidence has implicated obesity as having a negative effect on the development, treatment, and outcome of lower extremity pathologic entities, including diabetic foot disease. The objective of the present study was to increase the body of knowledge with respect to the effects of obesity on foot ...
Lambert Elisabeth A EA Human Neurotransmitters, Baker IDI Heart & Diabetes Institute, Melbourne, Victoria, - - 2014
Obesity is associated with elevated cardiovascular mortality, which may be attributed, in part, to sympathetic nervous system (SNS) activation and an associated poor metabolic profile. We examined the effects of laparoscopic adjustable gastric band (LAGB) on SNS activity and cardiovascular profile when the initial weight loss of 10%, corresponding to ...
Pilhatsch Maximilian M Department of Psychiatry and Psychotherapy, Technische Universität Dresden, Dresden, - - 2014
We studied whether suppressed secretion of the orexigenic peptide ghrelin might be involved in the anorexigenic effects of nicotine. Fifty healthy non-smokers chewed gums containing 2 mg nicotine, or no nicotine in a double-blind randomised crossover design in two independent studies. Plasma nonacylated ghrelin was not significantly affected by nicotine after ...
Toyoshima Hideaki H Health Care Center, Anjo Kosei - - 2014
Background: Chronic mental stress has been reported to be directly or inversely proportional to blood pressure (BP). To explain this inconsistent relationship, we assumed effect-modification by body mass index (BMI). Methods and Results: We examined 1,673 Japanese male local government employees who were not taking antihypertensive drugs or had no history of ...
Zhao Yanyan Y Division of Endocrinology, Department of Internal Medicine, The First Affiliated Hospital, Zhengzhou University , Zhengzhou , China - - 2014
Abstract We investigated blood nesfatin-1 levels in hypertension patients. We found that fasting plasma nesfatin-1 levels were significantly higher in hypertension patients than in control groups, especially in overweight/obese hypertension patients (4.5 ± 2.1 versus 3.3 ± 1.1 ng/ml, p < 0.01). Body mass index, systolic blood pressure and diastolic blood pressure were indeed positively correlated with ...
Kuwabara Masanari M 1] Division of Regenerative Medicine and Therapeutics, Institute of Regenerative Medicine and Biofunction, Tottori University Graduate School of Medical Sciences, Yonago, Japan [2] Department of Cardiology, Toranomon Hospital, Tokyo, Japan [3] Department of Cardiology, St Luke's International Hospital, Tokyo, - - 2014
The cause and effect relationship between serum uric acid levels and hypertension can be difficult to evaluate because antihypertensive drugs sometimes affect uric acid levels. This cross-sectional study investigated the relationship between serum uric acid levels and hypertension in a general, healthy Japanese population who were not receiving medication for ...
Chen Changbo C State Key Laboratory of Superhard Materials, College of Physics, Jilin University, Changchun 130012, People's Republic of - - 2014
High-pressure structures of MH2 (M = V, Nb) are explored through ab initio evolutionary methodology. As the same main group metal hydrides, VH2 and NbH2 adopt the same tetragonal structure with space group Fm-3m at low pressures. However, at high pressures VH2 and NbH2 possess Pnma and P63mc phases differently. ...
Alayoubi Alaadin A Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe , Monroe, LA , USA - - 2014
Abstract Recently there has been a growing interest in vitamin E for its potential use in cancer therapy. The objective of this work was therefore to formulate a physically stable parenteral lipid emulsion to deliver higher doses of vitamin E than commonly used in commercial products. Specifically, the objectives were ...
Pfeiffer Christine M CM National Center for Environmental Health, CDC, Atlanta, - - 2014
Little information is available on temporal trends in sodium intake in the U.S. population using urine sodium excretion as a biomarker. Our aim was to assess 1988-2010 trends in estimated 24-h urine sodium (24hUNa) excretion among U.S. adults (age 20-59 y) participating in the cross-sectional NHANES. We used subsamples from ...
Andrews Laura E LE Department of Neurology, University Health Care Center, Syracuse, N.Y., - - 2014
Idiopathic intracranial hypertension (IIH), also known as primary pseudotumor cerebri syndrome (PTCS), is a condition of unknown etiology which affects primarily overweight, reproductive-aged women and causes increased intracranial pressure (ICP). This review discusses the recently revised diagnostic criteria for PTCS for adults and children. Additionally, the role of obesity in ...
Kim Y-H YH Department of Family Medicine, Korea University College of Medicine, Seoul, - - 2014
ObjectiveElevated intraocular pressure (IOP) contributes to the progression of visual defects such as glaucoma. This study determined whether metabolic syndrome (MetS) and cardiovascular risk factors are associated with IOP in South Korean men.MethodsWe analyzed data on 4875 men who participated in the Korean National Health and Nutrition Examination Survey 2008-2010. ...
Martínez-Guerra E E Facultad de Ciencias Físico-Matemáticas, Universidad Autónoma de Nuevo León, Ciudad Universitaria 66450, San Nicolás de los Garza, NL, Mexico. Departamento de Física Aplicada, Centro de Investigación y de Estudios Avanzados del I.P.N., Cordemex 97310, Mérida, Yucatán, - - 2014
We present the structural, electronic and superconducting properties of Li2B2 under pressure within the framework of the density functional theory. The structural parameters, electronic band structure, phonon frequency of the E2g phonon mode and superconducting critical temperature Tc were calculated for pressures up to 20 GPa. We predicted that the superconducting ...
Ye Ran - - 2014
The effect of high pressure homogenization on the improvement of the stability hydroxypropyl cellulose (HPC) and micellar casein was investigated. HPC with two molecular weights (80 and 1150 kDa) and micellar casein were mixed in water to a concentration leading to phase separation (0.45% w/v HPC and 3% w/v casein) ...
Bloch Michael J MJ Department of Medicine, University of Nevada School of Medicine, Reno, NV, USA, - - 2014
Obesity and hypertension frequently coexist. Measuring blood pressure (BP) accurately in obese patients is challenging and may require strategies that are less accurate, such as forearm cuffing or use of wrist cuffs. Pathophysiologic mechanisms of hypertension may differ between obese and non-obese individuals, which may result in differing effects of ...
Liu Weiying W Department of Respiratory Medicine, First Hospital of Lanzhou University, Lanzhou, Gansu 730000, - - 2014
Obstructive sleep apnea syndrome (OSAS) is strongly associated with obesity and with cardiovascular disease. Ghrelin and obestatin are two peptides from the same source but have opposite roles. Both of them can affect feeding and regulate vascular tune. The aim of this study was to investigate the relationship between plasma ...
Preissler Claudia C Division of Gastroenterology, University Clinics of Visceral Surgery and Medicine, Bern, Switzerland. - - 2014
Mechanisms that ultimately lead to dysphagia are still not totally clear. Patients with laparoscopic gastric banding (LAGB) often complain about dysphagia, regurgitation and heartburn. Our aim was to evaluate the contribution of intrabolus pressure to symptoms of gastric banding. This study investigated 30 patients with LAGB before and 3 months ...
Son Sung-Min SM Department of Physical Therapy, College of Rehabilitation Science, Daegu University, Republic of - - 2014
[Purpose] The purpose of this study was to investigate the amount of plantar pressures on the lower limb during tilt table standing and to indicate the ideal degree of tilting for partial weight bearing. [Subjects and Methods] Fifteen healthy subjects between the ages of 20 and 30 were recruited as ...
Duburcq Thibault T 1 Inserm U859, F-59000 Lille, France ; 2 European Genomic Institute for Diabetes (EGID), FR 3508, F-59000 Lille, France ; 3 UNIV LILLE 2, F-59000 Lille, France ; 4 Inserm UMR 1011, F-59000 Lille, France ; 5 IPL, F-59000 Lille, France ; 6 Pole de Réanimation CHRU, F-59000 Lille, France ; 7 Centre de Biologie Pathologie CHRU, F-59000 Lille, - - 2014
Studies exploring the influence of obesity on septic shock remain limited and controversial. Pigs were chosen as a clinically relevant species, resembling to humans in various functions. We hypothese obesity may impair porcine acute endotoxic shock. Four groups of five "Yucatan" minipigs were studied: lean and obese control groups, lean ...
Cai Li L Johns Hopkins Bloomberg School of Public Health, Baltimore, MD; School of Public Health, Peking University Health Science Center, Beijing, - - 2014
Childhood overweight and obesity are associated with elevated blood pressure (BP). However, little is known about how childhood obesity lifestyle prevention programs affect BP. We assessed the effects of childhood obesity prevention programs on BP in children in developed countries. We searched databases up to April 22, 2013 for relevant ...
Asferg C L CL Department of - - 2014
To explore the putative associations of plasma copeptin, the C-terminal portion of provasopressin and a surrogate marker for arginine vasopressin secretion, with obesity-related health problems, such as hyperlipidaemia, hyperinsulinaemia, hyperglycaemia, high blood pressure and an android fat distribution. In 103 obese men (mean age ± standard deviation: 49.4 ± 10.2 years) and 27 normal weight ...
Roberts Evan E Department of History and Minnesota Population Center, University of Minnesota, 1110 Heller Hall, 271 19th Ave S, Minneapolis, MN 55455, United States. Electronic address: - - 2014
We provide new historical evidence on the developmental origins of health and disease in a cohort of boys born between 1907 and 1922 in Wellington, New Zealand. Using a dataset of 1523 birth records that include birth weight and length we find 852 (58%) of the adult cohort in World ...
Zhang Ying-Xiu YX Shandong Center for Disease Control and Prevention, 16992 Jingshi Road, Jinan, 250014, Shandong, China, - - 2014
It is well known that obesity is a key determinant of elevated blood pressure (BP) in children and adolescents. The present study compared the BP levels among children and adolescents with various types of obesity in a large population in China. A total of 38,822 students (19,456 boys and 19,366 ...
Seetho Ian W IW Department of Diabetes & Endocrinology, University Hospital Aintree, Longmoor Lane, Liverpool L9 7AL, United Kingdom. Electronic address: - - 2014
In a meta-analysis that investigated the effects of dietary sodium restriction in diabetes nephropathy, although blood pressure fell, there were significant increases in plasma renin and aldosterone levels. In this article, we hypothesise that in diabetic nephropathy, ACE-I or ARB treatment attenuates any rise in RAS hormones that might result ...
Kim S S Department of Family Medicine, Kangwon National University Hospital, Kangwondo, Republic of - - 2014
Background/objectives:A lower eating frequency (EF) has been suggested to be important in the development of cardiovascular risk factors such as obesity and hyperlipidemia. However, the association between EF and blood pressure (BP) remains unclear.Subjects/methods:The aim of this study was to explore the association of EF with BP and hypertension after ...
Lloyd-Sherlock Peter P School of International Development, University of East Anglia, Norwich, UK, Department of Ageing and Life Course, World Health Organization, Geneva, Switzerland National Research Council, Institute of Neuroscience, Padova, Italy, London School of Hygiene and Tropical Medicine, London, UK and Department of Health Statistics and Informatics, World Health Organization, Geneva, - - 2014
This study uses data from the World Health Organization's Study on Global Ageing and Adult Health (SAGE) to examine patterns of hypertension prevalence, awareness, treatment and control for people aged 50 years and over in China, Ghana, India, Mexico, the Russian Federation and South Africa. The SAGE sample comprises of ...
Dua Suman S Department of Anthropology, University of Delhi, - - 2014
The blood pressure and anthropometric measurements are important for evaluating the health of children, adolescents as well as adults. The aim is to study the blood pressure and body dimensions and to find out the prevalence of overweight/obesity and hypertension among adults. A cross-sectional study was conducted of all the ...
Baker William L WL Department of Pharmacy Practice, University of Connecticut School of Pharmacy, Storrs, CT, USA. Electronic address: - - 2014
Sodium-glucose co-transporter 2 (SGLT2) inhibitors represent a new class of antihyperglycemic agents that block renal sodium and glucose reabsorption and may reduce blood pressure (BP). We assessed the BP lowering ability of these agents using meta-analytic techniques. PubMed, SCOPUS, and Cochrane Central were searched through October 2013. We included fully ...
Peduzzi de Castro Marcelo M Center of Research, Education, Innovation and Intervention in Sport, School of Sport, University of Porto, Rua Dr. Plácido Costa, 91, 4200-450 Porto, Portugal; Activity and Human Movement Study Center/Department of Physiotherapy, School of Allied Health Science, Polytechnic Institute of Porto, Rua Valente Perfeito, 22, 4400-330 Vila Nova de Gaia, Portugal; Porto Biomechanics Laboratory, University of Porto, Rua Dr. Plácido Costa, 91, 4200-450 Porto, Portugal. Electronic address: - - 2014
The aims of this study were to test the effects of two pressure relief insoles developed for backpackers and obese people on the ground reaction forces (GRF) and plantar pressure peaks during gait; and to compare the GRF and plantar pressures among normal-weight, backpackers, and obese participants. Based on GRF, ...
Taylor Paul D PD Division of Women's Health, Women's Health Academic Centre, King's College London and King's Health Partners, London, - - 2014
Mother-child cohort studies have established that both pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) are independently associated with cardio-metabolic risk factors in young adult offspring, including systolic and diastolic blood pressure. Animal models in sheep and non-human primates provide further evidence for the influence of maternal obesity ...
Fontana Vanessa V Laboratory of Cardiovascular Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, SP, - - 2014
Activation of the renin angiotensin-aldosterone system (RAAS) and abnormal adipokine levels are biological alterations that affect blood pressure regulation and interact to link hypertension, obesity and metabolic diseases. While imbalanced levels of hormones produced by adipocytes including hypoadiponectinemia and hyperleptinemia were reported in hypertension, little is known about how antihypertensive ...
Seimon R V RV The Boden Institute of Obesity, Nutrition Exercise & Eating Disorders, University of Sydney, Sydney, NSW, - - 2014
Background/Objectives:The Sibutramine Cardiovascular OUTcomes (SCOUT) trial showed a significantly increased relative risk of nonfatal cardiovascular events, but not mortality, in overweight and obese subjects receiving long-term sibutramine treatment with diet and exercise. We examined the relationship between early changes (both increases and decreases) in body weight and blood pressure, and ...
Zaleski-Ejgierd Patryk P Institute of Physical Chemistry, Polish Academy of Sciences, ul. M. Kasprzaka 44/52, 02-144, Warszawa, Poland. - - 2014
A new class of binary iridium hydrides (IrxHy) is investigated in the 1 atm to 125 GPa pressure range at the ab initio level, using DFT. Upon compression a number of hydrides are predicted to stabilize in the excess hydrogen environment. Static stabilization pressure is calculated to be ∼14 and ...
Marcus Jonathan A JA Department of Neurology, University of Rochester Sleep Disorders Center, 2337 South Clinton Avenue, Rochester, NY, 14618, USA, - - 2014
The incidence of resistant hypertension, obesity, and obstructive sleep apnea (OSA), three highly prevalent conditions in the United States, is rising. Approximately one in three adults in the US has hypertension, and a significant proportion of these individuals have hypertension that is difficult to treat, or resistant. Obesity and OSA ...
Chopra Ishveen I Department of Pharmacy Administration, Duquesne University, Mylan School of Pharmacy, Pittsburgh, PA. - - 2014
Background: Obesity is associated with cardiovascular risk factors such as hypertension, dyslipidemia, and diabetes mellitus, as well as cardiovascular diseases. Objectives: To evaluate demographic, diagnostic, and treatment characteristics of patients with concomitant hypertension and dyslipidemia, stratified by body mass index and the attainment of blood pressure (BP) and lipid targets ...
Han Kyungdo K Department of Preventive Medicine, The Catholic University of Korea, Seoul, Korea ; Department of Biostatistics, The Catholic University of Korea, Seoul, - - 2014
Blood pressure (BP) is directly and causally associated with body size in the general population. Whether muscle mass is an important factor that determines BP remains unclear. To investigate whether sarcopenia is associated with hypertension in older Koreans. We surveyed 2,099 males and 2,747 females aged 60 years or older. ...
Hall Michael E ME Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA ; Department of Physiology and Biophysics, Mississippi Center for Obesity Research, University of Mississippi Medical Center, Jackson, MS, - - 2014
Obesity is a major risk factor for essential hypertension, diabetes, and other comorbid conditions that contribute to development of chronic kidney disease. Obesity raises blood pressure by increasing renal tubular sodium reabsorption, impairing pressure natriuresis, and causing volume expansion via activation of the sympathetic nervous system and renin-angiotensin-aldosterone system and ...
Pereira Elenilda J EJ School of Pharmacy, Universidade Federal do Rio de Janeiro, Rio de Janeiro, - - 2014
Because iron deficiency anemia is prevalent in developing countries, determining the levels of iron and zinc in beans, the second most consumed staple food in Brazil, is essential, especially for the low-income people who experience a deficiency of these minerals in their diet. This study aimed to evaluate the effect ...
Liu Shijiang S Department of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, - - 2014
To investigate the correlation and accuracy of transcutaneous carbon dioxide partial pressure (PTCCO2) with regard to arterial carbon dioxide partial pressure (PaCO2) in severe obese patients undergoing laparoscopic bariatric surgery. Twenty-one patients with BMI>35 kg/m2 were enrolled in our study. Their PaCO2, end-tidal carbon dioxide partial pressure (PetCO2), as well ...
Datta Banik Sudip S a Department of Human Ecology , Cinvestav-IPN, Unidad Mérida , Yucatan , - - 2014
This study was undertaken from 2009-2011 to understand the association between body mass index (BMI) and blood pressure (BP) (systolic or SBP and diastolic or DBP) among randomly chosen men, aged 30 to 59 years, of three endogamous communities in Darjeeling, West Bengal, India: Dhimal (n = 88), Mech (n ...
Lytsy Per P aDepartment of Medical Sciences, Uppsala University bDepartment of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University cDepartment of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala dDepartment of Health and Social Sciences, Högskolan Dalarna, Falun, - - 2013
Obesity and hypertension are associated, possibly through causal pathways involving insulin resistance and metabolic derangements. We aimed to investigate in a whites sample if overweight or obese persons without insulin resistance are at risk of developing hypertension or blood pressure progression. In a meta-analysis, using multivariable-adjusted mixed-effects logistic regression models, ...
Diaz Keith M KM aCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York bHypertension, Molecular, and Applied Physiology Laboratory, Department of Kinesiology, Temple University, Philadelphia, Pennsylvania cDepartment of Epidemiology, University of Alabama Birmingham, Birmingham, Alabama dVascular Health Laboratory, Department of Kinesiology & Nutrition, University of Illinois at Chicago, Chicago, Illinois, - - 2013
As evidence suggests visit-to-visit variability (VVV) of blood pressure (BP) is associated with cardiovascular events and mortality, there is increasing interest in identifying interventions that reduce VVV of BP. We investigated the effects of weight loss and sodium reduction, alone or in combination, on VVV of BP in participants enrolled ...
Murphy Gwendolyn G Community Health Division of the Community and Family Medicine Department, Duke Medical School, Duke University, Durham, North Carolina (Dr Murphy); Community and Behavioral Health, and Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa (Dr Snetselaar); Academy of Nutrition and Dietetics, Chicago, Illinois (Dr Myers); Healthcare Program Development, BlueCross BlueShield of North Carolina, Durham, North Carolina (Ms LaForge); BlueCross BlueShield of North Carolina, Durham, North Carolina (Ms Qualls and Dr Blackwelder); Dietetics Practice Based Research Network, Academy of Nutrition and Dietetics, Chicago, Illinois (Ms Hand); and BlueCross BlueShield of North Carolina, Durham, North Carolina (Dr Bradley). Ms Qualls is now with Duke Clinical Research Institute, Durham, North Carolina, and Dr Blackwelder is now with Cornerstone Health Enablement Strategic Services, High Point, North - - 2013
Self-reported health data are used by health insurance companies to assess risk. Most studies show underreporting compared with clinical measurements. To compare self-reported height, weight, blood pressure, waist circumference, and dietary intake with registered dietitian's (RD's) measures of the same parameters. This is a secondary analysis of data collected in ...
Ibuki Chikao C Cardiovascular Center, Nippon Medical School Chiba Hokusoh Hospital, Chiba, - - 2014
Hypertension is one of the most powerful predictor of the future cardiovascular events, and antihypertensive therapy adopting multiple drug regimen is often needed to obtain the appropriate blood pressure (BP) control. To clarify the blood pressure-lowering effect of the fixed-dose combination (FDC) of an angiotensin receptor blocker (ARB) and diuretic ...
Hsiao Tun-Jen - - 2013
The single-nucleotide polymorphism (SNP), rs1042714 or glutamine 27 glutamic acid (Gln27Glu), in the adrenoceptor β2 surface (ADRB2) gene has previously been examined for association with obesity with inconclusive results. The objective of this study was to determine whether the ADRB2 rs1042714 SNP could influence obesity and obesity-related metabolic traits in ...
Banzato C - - 2013
In adults, low levels of vitamin D are associated with hypertension. The aim of this study was to evaluate the relationship between 24-h blood pressure (BP) patterns and vitamin D levels in obese children. We recorded anthropometric parameters, took blood samples for 25-hydroxivitamin D measurements and monitored ambulatory BP (ABP) ...
Figueroa Arturo - - 2013
Obesity and reduced muscle strength are associated with increased blood pressure (BP). We examined the impact of milk proteins and combined exercise training (CET) on BP, arterial function, and muscle strength (one-repetition maximum (1-RM)). Thirty-three obese sedentary women (age = 30±1 years; body mass index = 35.2±0.9kg/m(2); systolic BP (SBP) ...
Higashino Ryota - - 2013
It has recently been recognized that increased central blood pressure is a predictor of cardiovascular disease. Central blood pressure is higher in obese individuals than in nonobese individuals. However, the effect of lifestyle modification on central systolic blood pressure in obese individuals is unclear. The aim of this study was ...
Boyraz M M Department of Pediatric Endocrinology and Diabetes, Fatih University, Faculty of Medicine, Ankara, Turkey. - - 2013
The aim of the present study was to analyze the relationship between epicardial adipose tissue thickness (EATT) and echocardiographic parameters, such as carotid intima-media thickness (cIMT), myocardial performance index (MPI), left ventricular (LV) systolic and diastolic function, and LV mass index in adolescents with obesity. One hundred and thirty eight ...
Kim Na Young NY Department of Pediatrics, Inje University Sanggye Paik Hospital, Seoul, - - 2013
Obesity is an important risk factor for hypertension in adolescents. We investigated the relationship of obesity-related indices (body mass index [BMI], waist-to-height ratio [WHR], and body fat percentage [%BF]) with blood pressure and the hemodynamic determinants of blood pressure in Korean adolescents. In 2008, 565 adolescents, aged 12-16 years, were ...
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