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Katout Mohammad - - 2013
Incretin therapies such as glucagon-like peptide 1 (GLP-1) agonists are commonly used for the treatment of type 2 diabetes mellitus. GLP-1 mimetics, besides improving glycemic control, have been shown to influence multiple pathways regulating blood pressure (BP). We investigated the GLP-1 analogs effects on BP from published randomized studies using ...
Ying-Xiu Zhang - - 2013
The present study examined the blood pressure (BP) characteristics of normal weight children and adolescents with a large waist circumference (WC) in a large population in Shandong, China. A total of 38,826 students (19,460 boys and 19,366 girls) aged 7-17 years participated in this study. Height, weight, WC, and BP of ...
Pal A - - 2013
Obesity has been regarded as a single best predictor and major controllable contributor to hypertension. The present study aimed to assess the relationship between body compositional and nutritional parameters with blood pressure in rural Bengalee adults. Anthropometric measures, blood pressure and nutritional parameters were measured in 522 rural Bengalee adults ...
Garimella Pranav S PS Division of Nephrology, Tufts Medical Center, Boston, Massachusetts, - - 2013
This review highlights recent developments in the management and monitoring of hypertension in adults with chronic kidney disease (CKD), not on dialysis. Ambulatory blood pressure (BP) monitoring and self-measured BP monitoring can classify abnormal BP patterns better than clinic BP readings. Self-measured BP monitoring lowers BP and allows tailoring of ...
Howards Penelope P - - 2013
There has been a long-standing debate about whether birth weight directly affects adult blood pressure, or whether the association is entirely mediated through current weight. In this issue of the Journal, Chiolero et al. (Am J Epidemiol. 2013;178(00):000-000) quantitatively evaluate whether bias from an unmeasured confounder of the relationship between ...
Bhagatwala Jigar J Georgia Prevention Center, Medical College of Georgia, Georgia Regents University, Augusta, GA; Department of Internal Medicine, Medical College of Georgia, Georgia Regents University, Augusta, - - 2014
Overactivity of the epithelial sodium channel (ENaC) is considered to be one mechanism underlying obesity-related blood pressure (BP) elevation. In an open-labeled, nonplacebo-controlled clinical trial (Clinicaltrials.gov: NCT-01308983), the authors aimed to comprehensively evaluate the effects of amiloride monotherapy, an ENaC blocker, on BP and cardiovascular risk in young adults with ...
Chiolero Arnaud - - 2014
To estimate the possible direct effect of birth weight on blood pressure, it is conventional to condition on the mediator, current weight. Such conditioning can induce bias. Our aim was to assess the potential biasing effect of U, an unmeasured common cause of current weight and blood pressure, on the ...
Espeland Mark A - - 2013
Objective: To assess whether weight loss improves markers of peripheral artery disease and vascular stenosis. Design and Methods: The Action for Health in Diabetes randomized clinical trial compared intensive lifestyle intervention (ILI) for weight loss to a control condition of diabetes support and education (DSE) in overweight or obese adults ...
Li Jinjin - - 2013
Despite its terrestrial abundance and astrochemical significance, many aspects of the phase diagram of solid carbon dioxide remain uncertain or unknown. The observed transition pressures from cubic to orthorhombic phase range widely from 2.5 GPa at 80 K to above 18 GPa at room temperature. The vibrational Raman bands that appear at higher ...
Rodilla Enrique - - 2013
The principal objective was to assess the prevalence of left ventricular hypertrophy (LVH) in hypertensive, never treated patients, depending on adjustment for body surface or height. Secondary objectives were to determine geometric alterations of the left ventricle and to analyze the interdependence of hypertension and obesity to induce LVH. Cross-sectional ...
Xiong Xiao-Qing - - 2013
Excessive sympathetic activity contributes to the pathogenesis of hypertension and the progression of the related organ damage. Adipose afferent reflex (AAR) is a sympatho-excitatory reflex that the afferent activity from white adipose tissue (WAT) increases sympathetic outflow and blood pressure. Hypothalamic paraventricular nucleus (PVN or PVH) is one of the ...
Higashino Ryota - - 2013
It has recently been recognized that increased central blood pressure is a predictor of cardiovascular disease. Central blood pressure is higher in obese individuals than in nonobese individuals. However, the effect of lifestyle modification on central systolic blood pressure in obese individuals is unclear. The aim of this study was ...
Miyoshi Hirokazu - - 2013
Hypertension and obesity each are well known to result in heart failure with preserved ejection fraction. Therefore, it is clinically important to clarify the mechanisms of further deterioration of left atrial (LA)-left ventricular (LV) interaction in asymptomatic patients with obesity in the presence of hypertension. Data on conventional and two-dimensional ...
Koebnick Corinna - - 2013
In the absence of evidence-based guidelines for high blood pressure screening in asymptomatic youth, a reasonable strategy is to screen those who are at high risk. The present study aimed to identify optimal body mass index (BMI) thresholds as a marker for high-risk youth to predict hypertension prevalence. In a ...
Nguyen-Tu Marie-Sophie - - 2013
The role of obesity in the appearance of skin pressure ulcers remains controversial. The aim of the present study was to evaluate blood perfusion and related lesions after skin compression in obese mice. Sixty C57BL6 male mice were randomly assigned to a control or hypercalorific diet (HCD) for 2, 4 ...
Xi Xiaoxiang - - 2013
We report the observation of two signatures of a pressure-induced topological quantum phase transition in the polar semiconductor BiTeI using x-ray powder diffraction and infrared spectroscopy. The x-ray data confirm that BiTeI remains in its ambient-pressure structure up to 8 GPa. The lattice parameter ratio c/a shows a minimum between 2.0-2.9 GPa, ...
Rodriguez-Escudero Juan P - - 2013
To assess the effect of a lifestyle therapy program using cardiac rehabilitation (CR) resources for patients at risk for metabolic syndrome (MetS). We designed a cardiometabolic program (CMP) using CR facilities and resources. We compared MetS components of 240 patients classified as either obese (body mass index, ≥30 kg/m) or ...
Gidding Samuel S - - 2013
To determine if obesity, blood pressure (BP), markers of inflammation, and insulin resistance are associated with cardiac structure in African-American adolescents, a cross-sectional study was performed on a cohort oversampled for high BP and obesity. Measurements included the following: anthropometrics, BP, homeostasis model assessment (HOMA) to assess insulin resistance, high-sensitivity ...
Becton Lauren J - - 2013
The common assumption is that blood pressure (BP) will decrease on subsequent readings. The objective of this study is to examine the prevalence and direction of BP classification change with repeat measurements and compare common clinical characteristics of groups of patients who do and do not have a change in ...
Das R K - - 2013
Body mass index (BMI) is an inexpensive and easy-to-perform method of screening for weight. In recent years, non-communicable diseases (NCD) like obesity, hypertension and Type-2 diabetes are on the increase in the developed and developing nations. This Analytical cross sectional study was done to appraise the effect of overweight and ...
Lemes Vinícius A F - - 2013
The insertion/deletion polymorphism in gene encoding the angiotensin-converting enzyme (ACE I/D) was associated with arterial hypertension and obesity in adults, but data in children are scarce and yielded contrasting results. We assessed the impact of the ACE I/D on blood pressure and obesity related traits in a Brazilian cohort of ...
Kang In Sook - - 2013
Central obesity has been reported as a risk for atherosclerosis and metabolic syndrome. The influence of central obesity on diurnal blood pressure (BP) has not been established. In this study, we investigated the influence of central obesity on the circadian parameters of BP by 24 hr ambulatory BP monitoring. Total ...
Valcamonico Francesca - - 2013
Idiopathic intracranial hypertension is a variety of intracranial hypertension that is extremely rare in men. Obesity and hypogonadism are the most important predictive factors. Etiological hypotheses include increased central venous pressure, and various hormonal and metabolic changes commonly found in obese patients. We described the case of an obese man ...
Kumara Wa Nuwan - - 2013
To study the prevalence and define deferential risk factors for 'Resistant' hypertension (RHT) in a hypertensive population of South Asian origin. A descriptive cross-sectional study was carried out among hypertensive patients attending clinics at the Cardiology Unit, Colombo from July-October 2009. All the patients with hypertension who provided informed written ...
Efthimiopoulos Ilias - - 2013
Selected members of the A2B3 (A = Sb, Bi; B = Se, Te) family are topological insulators. The Sb2Se3 compound does not exhibit any topological properties at ambient conditions; a recent high-pressure study, however, indicated that pressure transforms Sb2Se3 from a band insulator into a topological insulator above ~2 GPa; in ...
Kuwahara Erika - - 2013
The aim of this study was to clarify the relationship between long-term changes in body mass index (BMI) during childhood and adolescent blood-pressure levels in a general Japanese population. We used health report data from 900 Japanese children between 1983 and 2007. After adjusting for baseline BMI and other confounding ...
Simino Jeannette - - 2013
Candidate gene and twin studies suggest that interactions between body mass index (BMI) and genes contribute to the variability of blood pressure (BP). To determine whether there is evidence for gene-BMI interactions, we investigated the modulation of BP heritability by BMI using 4,153 blacks, 1,538 Asians, 4,013 whites, and 2,199 ...
Di Chiara Tiziana - - 2013
This study has been designed to evaluate the impact of adiponectin levels on left ventricular geometry and function in visceral obesity-associated hypertension. 94 consecutive subjects, 53 of them were hypertensives and 41 normotensives with age ≤ 65 years, subgrouped according to the presence or absence of visceral obesity, were studied. ...
Gröber-Grätz Dagmar - - 2013
Background: In order to assess the relationship between hypertension or dyslipidemia and obesity, the body mass index (BMI) is usually used. Unlike waist circumference (WC), BMI does not reflect body fat distribution. The aim of this study is to investigate whether BMI or WC is a better predictor of hypertension ...
Croymans D M - - 2013
Central blood pressure is a predictor of the risk of cardiovascular disease (CVD), and the effects of resistance training (RT) on central blood pressure are largely unknown. This study explored the effects of high-intensity RT on central blood pressure, indices of arterial stiffness and wave reflection and inflammatory/atherogenic markers in ...
Goldberg Gail R GR Medical Research Council Human Nutrition Research, Cambridge, United - - 2013
Dietary calcium intake in rural Gambian women is very low (∼350 mg/d) compared with international recommendations. Studies have suggested that calcium supplementation of women receiving low-calcium diets significantly reduces risk of pregnancy hypertension. We tested the effects on blood pressure (BP) of calcium carbonate supplementation (1500 mg Ca/d) in pregnant, ...
Akintunde Aa - - 2013
Cardiac adaptation to hypertension and obesity may be related to many factors such as race, gender and haemodynamic status. Some gender specific associations with left ventricular structure and function have been described among Caucasians. To describe the sex specific pattern of left ventricular adaptations to obesity and hypertension among Nigerians. ...
Laganović Mario - - 2013
Individuals born small for gestational age (SGA) are supposed to be at higher risk to develop cardiovascular disorders, and recent report showed that concurrent obesity influences blood pressure (BP) in SGA children. Our aim was to investigate the impact of obesity and birth weight on blood pressure values in young ...
Vujicić Bozidar - - 2013
Hypertension is a common finding in end-stage renal disease patients with the prevalence between 20 to 85%. Although the etiology of arterial hypertension (AH) in this patient group is multifactorial, sodium and volume excess leading to extracellular volume overload are one of the most important and potentially adjustable causes. Control ...
Pećin Ivan - - 2013
The objective of this study was to determine the prevalence of hypertension, overweight and obesity in Croatian adolescents. In this cross-sectional survey (the sub-study of the EH-UH study) 375 boys and 381 girls (mean age 15.9 +/- 0.5 years) from four high schools in the city of Koprivnica were enrolled. ...
Stroescu Ramona R "Louis Turcanu" Emergency Hospital for Children Timisoara, Romania ; "Victor Babes" University of Medicine and Pharmacy Timisoara, - - 2013
The "catch-up growth" phenomenon in children born small for gestational age (SGA) has been linked to early onset obesity with the subsequent emergence of metabolic syndrome (MetS). The intima media thickness of the common carotid artery (CIMT) is a well-known marker of subclinical atherosclerosis. to determine the association between being ...
Ovsyannikov Sergey V - - 2013
We report results of a powder x-ray diffraction (XRD) study of vanadium sesquioxide, V2O3, under pressurization in a neon pressure-transmitting medium up to 57 GPa. We have established a bulk modulus value for corundum-type V2O3 of B0 = 150 GPa at B' = 4. This bulk modulus value is the lowest among those known for the ...
Derosa Giuseppe - - 2013
Background: Metabolic syndrome is becoming a common disease due to a rise in obesity rates among adults. Objectives: The aim was to evaluate the effects of canrenone compared to placebo on metabolic and inflammatory parameters in patients affected by metabolic syndrome. A total of 145 patients were treated with placebo ...
Ljubičić Anita - - 2013
Flashover training (FOT) for firefighters is a simulation of the flashover phenomenon under controlled conditions. This study assessed arterial blood pressure (BP) and its response to thermal and physical strain during FOT in 48 professional and 18 volunteer firefighters. A high prevalence of obesity (27%), basal hypertensive (53%) and prehypertensive ...
Anese Monica - - 2014
Coffea arabica beans were roasted in an oven at 200°C for increasing lengths of time under vacuum (i.e. 0.15kPa). The samples were then analysed for colour, weight loss, acrylamide concentration and sensory properties. Data were compared with those obtained from coffee roasted at atmospheric pressure (i.e. conventional roasting), as well ...
López-Monclova Julio - - 2013
Laparoscopic sleeve gastrectomy (LSG) consists of a longitudinal resection of the stomach on the greater curvature, removing 75-80 % of the stomach approximately and creating a cylindrical "sleeve"-like conduit. However, LSG can be associated with significant morbidity, and staple-line failure with dehiscence and gastric leak is one of the most severe ...
Engeli Stefan - - 2013
Hypertension and obesity often coexist, exposing patients to cardiovascular and metabolic risks, particularly type 2 diabetes mellitus. Moreover, obesity may render hypertensive patients treatment resistant. We review how drugs recently approved for obesity or type 2 diabetes mellitus treatment affect blood pressure. The weight-reducing drug lorcaserin induces modest reductions in ...
Yu Zhangsheng - - 2013
To comparatively examine the effects of adiposity on the levels of plasma renin activity (PRA), plasma aldosterone concentration (PAC), and aldosterone-renin ratio (ARR) in young black and white children. We prospectively assessed 248 black and 345 white children and adolescents. A novel analytical technique was used to assess the concurrent ...
Lemyze Malcolm - - 2013
To evaluate the extent to which sitting position and applied positive end-expiratory pressure improve respiratory mechanics of severely obese patients under mechanical ventilation. Prospective cohort study. A 15-bed ICU of a tertiary hospital. Fifteen consecutive critically ill patients with a body mass index (the weight in kilograms divided by the ...
Zarrati Mitra - - 2013
Background: Birth weight appears to play a role in determining high blood pressure (BP) and obesity during childhood. The purpose of this study is to investigate the association between birth weight and later obesity and hypertension among 10- to 13-year-old schoolchildren. Methods: A total of 1,184 primary school students were ...
Bucher Barbara S - - 2013
There is growing concern about elevated blood pressure in children and adolescents, because of its association with the obesity epidemic. Moreover, cardiovascular function and blood pressure level are determined in childhood and track into adulthood. Primary hypertension in childhood is defined by persistent blood pressure values ≥ the 95th percentile ...
Park Seung Ha - - 2013
Low muscle mass has been associated with arterial stiffness. The aim of the study was to determine whether sarcopenic obesity is associated with hypertension. Subjects consisted of 6832 adults who participated in the 2009 Korea National Health and Nutrition Examination Survey. Participants were classified as normal, sarcopenic, obese, or sarcopenic-obese ...
Mark Allyn L AL Department of Internal Medicine and the Obesity Research and Education Initiative, University of Iowa Carver College of Medicine, Iowa City, - - 2013
In addition to effects on appetite and metabolism, leptin influences many neuroendocrine and physiological systems, including the sympathetic nervous system. Building on my Carl Ludwig Lecture of the American Physiological Society, I review the sympathetic and cardiovascular actions of leptin. The review focuses on a critical analysis of the concept ...
Marcadenti Aline - - 2013
Genetic variants of the FTO gene rs9939609 A/T and the MC4R gene rs17782313 C/T have been associated with obesity. Individuals with mutations in MC4R gene have lower blood pressure (BP), independently of obesity. This study aimed to investigate the association of FTO rs9939609 and MC4R rs17782313 with anthropometric indexes, BP, ...
Yang Yuping - - 2013
In situ Raman spectroscopic measurements of H2O-NaCl systems with three different salinities (0, 5.0, and 10.0 wt% NaCl) in the region of O-H stretching vibration were obtained at pressures up to 1800 MPa and temperatures from 298 to 453 K, with a hydrothermal diamond-anvil cell. The peak position was determined ...
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