Search Results
Results 251 - 300 of 1405
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Pini Riccardo - - 2008
OBJECTIVES: The present study investigated whether central blood pressure (BP) predicts cardiovascular (CV) events better than brachial BP in a cohort of normotensive and untreated hypertensive elderly individuals. BACKGROUND: Limited and conflicting data have been reported on the prognostic relevance of central BP compared with brachial BP. METHODS: Community-dwelling individuals ...
Mangoni Arduino A - - 2008
BACKGROUND: Hemodialysis (HD) is associated with significant reductions in the plasma concentrations of the nitric oxide (NO) inhibitors N(G)-monomethyl L-arginine (L-NMMA), asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA). We sought to determine whether elevated concentrations of these NO inhibitors pre-HD and/or their acute decrease during HD might mediate intradialytic hypotension ...
Charest Eve - - 2008
Introduction: Combination of prophylactic phenylephrine (PHE) 100mcg/min and crystalloid cohydration is effective in reducing incidence of maternal hypotension during spinal anesthesia for cesarean delivery (1). However, this regimen is associated with a significant incidence of hypertension. We hypothesized that reducing PHE rate would result in a lower incidence of hypertension ...
Baek In-hwan - - 2008
Pharmacokinetic-pharmacodynamic (PK/PD) analysis is useful study in clinical pharmacology, also PK/PD modeling is major tools for PK/PD analysis. In this study, we sought to characterize the relationship between the cardiovascular effects and plasma concentrations of the beta blocker drugs carvedilol and atenolol using PK/PD modeling in healthy humans. One group ...
Safar M E - - 2008
Macrovasculature, microvasculature and the heart determine the structure and function of the circulatory system. Due to the viscoelastic properties of large arteries, the pulsatile pressure and flow that result from intermittent ventricular ejection is smoothed out, so that microvasculature mediates the delivery of nutrients and oxygen to tissues steadily. The ...
Maki K C - - 2008
Rebaudioside A and stevioside are steviol glycosides extracted from the plant Stevia rebaudiana Bertoni and are used in several countries as food and beverage sweeteners. This randomized, double-blind trial evaluated the hemodynamic effects of 4weeks consumption of 1000mg/day rebaudioside A vs. placebo in 100 individuals with normal and low-normal systolic ...
Vimaleswaran Karani Santhanakrishnan KS Department of Public Health & Clinical Medicine, Umeå University Hospital, Umeå, - - 2008
The protein encoded by the PPARGC1A gene is expressed at high levels in metabolically active tissues and is involved in the control of oxidative stress via reactive oxygen species detoxification. Several recent reports suggest that the PPARGC1A Gly482Ser (rs8192678) missense polymorphism may relate inversely with blood pressure. We used conventional ...
Samara Anastasia - - 2008
BACKGROUND: Leptin is an adipokine initially considered as a molecule related exclusively to obesity but advances in research revealed its multiple roles in other physio-pathological mechanisms and particularly in the inflammatory ones. The aim of the present study was to demonstrate the presence of leptin in human Peripheral Blood Mononuclear ...
Silver Brian - - 2008
Hypertension is the most important modifiable risk factor for secondary stroke prevention but the immediate management of blood pressure after stroke is uncertain. We evaluated outcomes in the NINDS tPA stroke study in relation to blood pressure declines during the first 24 h after randomization. Declines in blood pressure compared ...
Cardoso Claudia R L - - 2008
The pathophysiological mechanisms linking cardiovascular dysautonomy to mortality are unclear. The aim of this study was to investigate the pattern of 24-h ambulatory blood pressure (BP) monitoring (ABPM) in diabetic patients with cardiovascular autonomic neuropathy (CAN). We evaluated 391 type 2 diabetic patients in a cross-sectional study. Five clinical tests ...
Clijsen Ron - - 2008
BACKGROUND/AIMS: In physiotherapy, fango (mud) application is a frequently used heat therapy. The main therapeutic effects are due to the elevated temperature of the different tissues with a significant redistribution of blood towards the heated area. This may influence several cardiovascular parameters. There is only limited information on the effect ...
Matsui T - - 2008
In order to avoid the secondary exposure of medical personnel to toxic materials under biochemical hazard conditions, we have reported a method for non-contact monitoring of heart and respiratory rates, using microwave radar or laser irradiation. In large-scale disasters, it is important to be able to diagnose shock without touching ...
Anand Inder S - - 2008
BACKGROUND: Low systolic blood pressure (SBP) is a risk factor for adverse outcomes in patients with heart failure (HF). Valsartan improved morbidity rates in the Valsartan Heart Failure Trial (Val-HeFT) despite a reduction in SBP. The aim of the present study was to investigate the relationship between the SBP-lowering effects ...
Kostis John B - - 2008
This post-hoc analysis of the Treating to New Targets (TNT) study evaluated the joint effects of managing low-density lipoprotein cholesterol (LDL-C) and systolic blood pressure (SBP) on cardiovascular outcomes. Patients (N=9739) with clinically evident, stable coronary heart disease (CHD) were randomized to atorvastatin 10 or 80 mg/d. The primary end ...
Brooks Ellen R - - 2008
OBJECTIVE: The purposes of our study were to: (1) assess if changes in the volemic status of children and adolescents over the course of standard dialysis could be observed using bioelectric impedance (BIA); and (2) evaluate whether the variability of blood pressure (systolic blood pressure, SBP; diastolic blood pressure, DBP) ...
Hirai Flavio E - - 2009
PURPOSE: To describe the frequency of orthostatic hypotension and hypertension and associations with risk factors in a cohort of persons with long-term Type 1 diabetes (n=440) participating in the Wisconsin Epidemiologic Study of Diabetic Retinopathy. METHODS: Evaluations included detailed medical history, electrocardiography (ECG), and laboratory tests. Blood pressure (BP) was ...
Colao Annamaria - - 2008
CONTEXT: Approximately one-third of patients with acromegaly have concomitant hypertension. The outcome of hypertension after treatment of acromegaly is unknown. OBJECTIVE: To evaluate the role of GH and IGF-I control on systolic (SBP) and diastolic blood pressure (DBP) levels. PATIENTS: One hundred and five hypertensive patients (60 women, 45 men) ...
Nakae Ichiro - - 2008
The authors examine the clinical significance of radial augmentation index (rAI) and brachial-ankle pulse wave velocity (baPWV). In 78 hypertensive patients, rAI correlates inversely with pulse rate (PR; r = -0.57, P < .001), but baPWV does not. A weak correlation between rAI and systolic blood pressure (SBP) is observed ...
Kotani Kazuhiko - - 2008
Gamma-glutamyl transferase (GGT) is an enzyme present in serum and on most cell surfaces and serves as an oxidative stress marker. Although serum GGT is associated with hypertension development, little data are available on the associations between GGT and hypertension among populations with diabetes mellitus (DM). Our aim was to ...
Chen Shuzhen - - 2008
A bond graph model of the cardiovascular system with embedded autonomic nervous regulation was developed for a better understanding of the role of the autonomic nervous system (ANS) in hypertension. The model is described by a pump model of the heart and a detailed representation of the head and neck, ...
Ryan Kathy L - - 2008
OBJECTIVE: Manual assessment of radial arterial pulse character remains an important determinant of physiological status in military and civilian casualties. This study hypothesized that changes in radial pulse character and mental status (presyncopal symptoms) in humans occur only during the later stages of progressive reductions in central blood volume in ...
Cheng Li-Tao - - 2008
The aim of this study was to validate whether differences in aortic stiffness are responsible for the differences in cardiovascular mortality among hypertension subtypes. Twenty hundred and fifty continuous ambulatory peritoneal dialysis patients were included in the present study. They were classified into four groups: normotensives (n=92) with systolic blood ...
Jaja S I - - 2008
INTRODUCTION: Studies have shown that oral, chronic, low dose vitamin C reduces blood pressure and forearm blood flow in normal young adults or hypertensive patients. It is not clear how vitamin C affects cardiac function or autonomic control of blood pressure in young apparently healthy adults. AIM: This study was ...
Guimarães Guilherme Veiga - - 2008
The six-minute walk test (6WT) has been proposed to be a submaximal test, but could actually demand a high level of exercise intensity from the patient, expressed by a respiratory quotient >1.0, following the guideline recommendations. Standardizing the 6WT using the Borg scale was proposed to make sure that all ...
Auchincloss Amy H AH Department of Epidemiology, School of Public Health, University of Michigan, 109 Observatory St., SPH Tower Room 3655, Ann Arbor, MI 48109-2029, USA. - - 2008
Blood pressure (BP) may be implicated in associations observed between ambient particulate matter and cardiovascular morbidity and mortality. This study examined cross-sectional associations between short-term ambient fine particles (particulate matter <or= 2.5 microm in aerodynamic diameter; PM(2.5)) and BP: systolic (SBP), diastolic (DBP), mean arterial (MAP), and pulse pressure (PP). ...
Xi Gui-Lin GL Center for New Drug Evaluation, Second Military Medical University, Shanghai, - - 2008
Hypertension is a major risk factor for cardiovascular disease, and data regarding the efficacy and tolerability of telmisartan compared with losartan on blood pressure (BP) control in patients with hypertension. Pertinent studies were selected through extensive searches of PubMed (1966 to 29 December 2007), Embase (1980 to 29 December 2007), ...
Silverstein Deborah C - - 2008
OBJECTIVE: To evaluate the relationship between Doppler blood pressure (DBP) and survival or response to treatment in critically ill cats. DESIGN: Retrospective case series. ANIMALS: 83 cats. PROCEDURES: Medical records from cats admitted to the intensive care unit with at least 2 recorded DBP measurements were included in the study. ...
Jolly K - - 2009
OBJECTIVE: To compare the outcomes of home-based (using the Heart Manual) and centre-based cardiac rehabilitation programmes. DESIGN: Randomised controlled trial and parallel economic evaluation. SETTING: Predominantly inner-city, multi-ethnic population in the West Midlands, England. PATIENTS: 525 patients referred to four hospitals for cardiac rehabilitation following myocardial infarction or coronary revascularisation. ...
Dusek Jeffery A - - 2008
Isolated systolic hypertension is common in the elderly, but decreasing systolic blood pressure (SBP) without lowering diastolic blood pressure (DBP) remains a therapeutic challenge. Although stress management training, in particular eliciting the relaxation response, reduces essential hypertension its efficacy in treating isolated systolic hypertension has not been evaluated. We conducted ...
Torrens Christopher - - 2008
We have previously demonstrated that maternal protein restriction during pregnancy leads to raised blood pressure and endothelial dysfunction in the offspring (F1). Here we show that these characteristics are transmitted to the F2 offspring through the maternal line, in the absence of any additional challenges to the F1. Female Wistar ...
Huang C-C - - 2008
Blood pressure (BP) response to diuretics is varied in hypertensive patients. This study aimed to identify the patients who may respond better or worse to thiazide diuretics. Nondiabetic patients with treated or untreated hypertension were evaluated if they did not take diuretics and their office systolic BP (SBP) >140 mm ...
Perricone Nicholas V - - 2008
Excessive intake of sugars significantly elevates systolic blood pressure (SBP) in susceptible rats. Although the exact pathological mechanisms behind sugar-induced hypertension are uncertain and may be multiple, disturbances in the renin-angiotensin system (RAS) manifested by elevated circulating levels of angiotensin-2 may be involved. We attempted to confirm that the RAS ...
Eguchi Kazuo K Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan. - - 2008
The prognostic significance of ambulatory blood pressure (ABP) has not been established in patients with type 2 diabetes (T2DM). In order to clarify the impact of ABP on cardiovascular prognosis in patients with or without T2DM, we performed ABP monitoring (ABPM) in 1,268 subjects recruited from nine sites in Japan, ...
Musunuru Kiran - - 2008
We sought to evaluate this "response-to-injury" hypothesis of atherosclerosis by studying the interaction between systolic blood pressure (SBP) and LDL- cholesterol (LDL-C) in predicting the presence of coronary artery calcification (CAC) in asymptomatic men. We studied 526 men (46+/-7 years of age) referred for electron-beam tomography (EBT) exam. The prevalence ...
Ishii Yoshinori - - 2008
This study reports the comparison of the clinical use of a new tourniquet system for total knee arthroplasty that can determine its pressure in synchrony with systolic blood pressure (SBP) with the conventional that keeps the initial setting pressure. We prospectively applied the additional pressure of 100 mm Hg based ...
Ishikawa Tomofumi - - 2008
BACKGROUND: Microalbuminuria is recognized as a marker of generalized vascular dysfunction. However, the associations between microalbuminuria and pulse wave velocity (PWV), carotid intima-media thickness (IMT), and ambulatory blood pressure (ABP), respectively, have not been investigated. METHODS: Brachial-ankle PWV (baPWV), IMT, and ABP were determined in 328 individuals (mean age, 65.7 ...
Stergiou George S - - 2008
OBJECTIVE: Assessment of the accuracy of the A&D UM-101 mercury-free professional device for auscultatory blood pressure (BP) measurement according to the European Society of Hypertension International Protocol. Further to auscultation, the device has a button to mark readings during deflation. METHODS: Fifteen adults were included in phase 1 and another ...
Rebelo Duarte - - 2008
BACKGROUND: Little information exists regarding the effect of several obesity markers on blood pressure (BP) levels in youth. DESIGN: Transverse study including 2494 boys and 2589 girls. METHODS: Height, weight and waist were measured according to the international criteria and body fat (BF) by bioimpedance. BP was measured by an ...
- - 2008
OBJECTIVE: To compare the performance of body mass index (BMI) against waist circumference, waist: hip ratio (WHR) and waist: height ratio in the discrimination of hypertension in ethnically diverse populations. METHODS: Meta-analysis of 19 cross-sectional studies. MAIN OUTCOME MEASURES: Discrimination of hypertension (SBP/DBP > or = 140/90 mmHg) was adjudicated ...
de Vos Nathan J - - 2008
OBJECTIVE: To quantify acute changes in blood pressure and heart rate during a maximal dynamic strength-single-repetition maximum lift (1-RM)-testing session in older adults with a low burden of chronic disease. DESIGN: Descriptive, cross-sectional study. SETTING: University rehabilitation center. PARTICIPANTS: Volunteer sample of 43 community-dwelling, nonresistance-trained older adults aged 60 years ...
Gavish Benjamin - - 2008
OBJECTIVES: Systolic blood pressure (SBP) and diastolic blood pressure (DBP) frequently display a linear relationship characterized by the systolic-versus-diastolic slope ('Slope') or the 'ambulatory arterial stiffness index' [AASI = 1 - (diastolic-versus-systolic Slope)] and the correlation coefficient r. We evaluated the effect of using symmetric regression on the AASI and ...
Dost Axel - - 2008
OBJECTIVE: Arterial hypertension is a key player in the development of diabetes complications. We used a nationwide database to study risk factors for abnormal 24-h blood pressure regulation and microalbuminuria in children and adolescents with type 1 diabetes. RESEARCH DESIGN AND METHODS: Ambulatory blood pressure monitoring was performed in 2,105 ...
Smulyan Harold - - 2008
BACKGROUND: The brachial artery (BA) mean blood pressure (MBP) is now readily available using the oscillometric technique. In contrast to the auscultatory method where MBP is calculated from the systolic (SBP) and diastolic blood pressure (DBP), oscillometric MBP is measured separately from either SBP or DBP. Because the peripheral MBP ...
Ried Karin - - 2008
BACKGROUND: Non-pharmacological treatment options for hypertension have the potential to reduce the risk of cardiovascular disease at a population level. Animal studies have suggested that garlic reduces blood pressure, but primary studies in humans and non-systematic reviews have reported mixed results. With interest in complementary medicine for hypertension increasing, it ...
Brotman Daniel J - - 2008
BACKGROUND: Most healthy people exhibit a decrease in systolic blood pressure (SBP) at night. A drop of <10% from mean daytime values, "non-dipping," is associated with kidney disease and cardiovascular events. We hypothesized that non-dipping would predict all-cause mortality. METHODS: Consecutive patients referred for ambulatory blood pressure (BP) monitoring at ...
Karpitskaya Yekaterina - - 2008
This study assesses the relationship between capillary refill time (CRT) and arterial blood flow (ABF) in the lower extremities of pediatric patients to determine if a correlation exists that would demonstrate CRT as an accurate means of monitoring tissue perfusion. The ABF and CRT were evaluated in 20 pediatric patients ...
Ibrahim Nahla K - - 2008
Hypertension (HTN) is most likely the most common disease on Earth. It represents the single greatest preventable cause of death in humans and one of the most important modifiable risk factors for cardiovascular diseases. The purpose of this study was to investigate the prevalence and associated risk factors of HTN ...
Weycker Derek - - 2008
OBJECTIVE: To describe the real-world effectiveness of amlodipine add-on therapy for hypertensive patients receiving valsartan. METHODS: Retrospective cohort study based on USA electronic medical records. The study population included hypertensive patients who, between January 1998 and December 2005, were receiving valsartan and subsequently initiated add-on therapy with amlodipine. Change in ...
Valera Beatriz - - 2008
BACKGROUND: Mercury is a contaminant that reaches high levels in Nunavik (North of Quebec). It is transformed into methylmercury (MeHg) and accumulated in marine mammals and predator fish, an important part of the traditional Inuit diet. MeHg has been suggested to affect BP in adults and children while the influence ...
Judd Suzanne E - - 2008
The prevalences of both hypertension and vitamin D insufficiency are high in the United States. Recent clinical trials and animal studies have suggested that vitamin D insufficiency may be associated with elevated blood pressure. With cross-sectional data, we sought to determine whether vitamin D concentrations were related to systolic blood ...
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