Search Results
Results 401 - 450 of 1745
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Sajjadi Seyed A - - 2006
OBJECTIVE: We evaluated the correlation between intracranial (ICP) and intraocular pressure (IOP). METHODS: Of the 77 patients who underwent a lumbar puncture, 27 were excluded secondary to a history of glaucoma, using drugs effective on IOP, and abnormal funduscopic examination. ICP was measured by lumbar puncture. IOP was measured by ...
Baddon A C J - - 2007
PURPOSE: To test the agreement of intraocular pressure (IOP) measurements made with Luneau SA applanators and Goldmann applanator. MATERIALS AND METHODS: A single-blind crossover trial. IOPs were measured in both eyes of subjects with both applanators. Type of applanator was alternated to eliminate systematic bias. Multiple observers were used. Observers ...
Jonas J B - - 2007
PURPOSE: To evaluate whether the amplitude of day-and-night intraocular pressure (IOP) profiles influences the rate of progression of chronic open-angle glaucoma. METHODS: The hospital-based clinical observational study included day-and-night profiles of IOP measurements performed on 458 patients (855 eyes) with chronic open-angle glaucoma or ocular hypertension. The 24-h pressure profiles ...
Davies Leon N - - 2006
PURPOSE: To evaluate the reliability and repeatability of intraocular pressure (IOP) measurements using a new rebound tonometer. METHODS: Intraocular pressure was measured in 42 healthy human eyes of subjects aged 18-30 years (mean +/- standard deviation [SD] 21.5 +/- 3.2 years) using the ICare Rebound and Goldmann tonometers in two ...
Kniestedt Christoph - - 2006
PURPOSE: To determine the correlation of central corneal thickness (CCT) to Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT, PASCAL), and to glaucoma stage as assessed by cup-to-disc ratio (CDR). DESIGN: Prospective, cross-sectional tricenter observation study. PATIENTS AND METHODS: From three glaucoma specialty practices a sample of 406 independent ...
Ventura Lori M LM Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, Florida 33136, USA. - - 2006
Several studies have shown that the pattern electroretinogram, a direct, objective method of measuring retinal ganglion cell function, is altered early in ocular hypertension and glaucoma. Renewed interest in the pattern electroretinogram for early detection of pre-perimetric glaucoma has been sparked by noninvasive and reproducible methods of recording using skin ...
van der Valk Rikkert - - 2006
PURPOSE: To describe changes in glaucoma treatment and achieved IOP (intraocular pressure) over the period 1995-2002, 4 years before and 4 years after new glaucoma drugs had become available (January 1999). METHODS: An observational study was conducted in primary open-angle glaucoma (suspect), and ocular hypertension patients (n=1561) who had started ...
Schmidt Kristiane S - - 2006
OBJECTIVE: The objective of the study was to determine the effects of systemic 0.5% tropicamide on intraocular pressure (IOP), pupillary diameter (PD), blood pressure, and heart rate (HR) in normal felines with normotensive eyes. PROCEDURES: Intraocular pressure, PD, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MBP), ...
Kohlhaas Markus - - 2006
PURPOSE: To create a correction formula to determine the real intraocular pressure (IOP) after LASIK considering the altered corneal thickness, corneal curvature, and corneal stability. METHODS: This prospective clinical trial comprised 101 eyes of 59 patients (34 women and 25 men) that underwent LASIK with a mean preoperative spherical equivalent ...
Laiquzzaman Mohammad - - 2006
BACKGROUND: This study was conducted to assess the diurnal variation in ocular hysteresis, as measured by the Ocular Response Analyser to establish a relationship between diurnal hysteresis variation and diurnal intraocular pressure (IOP) variation. METHODS: Forty-two normal eyes of 21 colleagues and staff in a teaching hospital in Birmingham, UK, ...
Choi Jaewan - - 2006
PURPOSE: To study blood pressure (BP), intraocular pressure (IOP), and mean ocular perfusion pressure (MOPP) in patients with untreated normal tension glaucoma (NTG), and to investigate the relationship between circadian MOPP fluctuation and visual field status at initial presentation. METHODS: IOP and BP were evaluated in hospital over 24 hours ...
Albrecht May C - - 2006
Long-term intraocular pressure (IOP) elevation leads to a significant reduction of the intrinsic choroidal innervation and axon loss in the optic nerve. In this study we investigated early changes in these tissues in order to clarify the putative sequence of events between choroidal ganglion cell loss and optic nerve axon ...
Ku J Y F - - 2006
AIMS: To compare the intraocular pressure (IOP) measurements obtained using the Pascal dynamic contour tonometer (PDCT) with the standard Goldmann applanation tonometer (GAT) and to correlate these with central corneal thickness (CCT) in patients with normal corneas. METHODS: A prospective, masked, comparative case series of 116 eyes from patients attending ...
Horn Folkert K - - 2006
BACKGROUND: Vascular dysregulation in open-angle glaucomas can be identified by measuring the blood circulation during exposure to cold water. Aim of this study was to find out whether the same cold stimulus would lead to functional changes in the visual evoked potentials (VEP) of the short-sensitive pathway in normals and ...
Birchall W - - 2007
AIM: To compare the effect on intraocular pressure (IOP) of large vs small scleral flap size during trabeculectomy using adjustable sutures. METHODS: Trabeculectomy operations were performed on nine donor human eyes connected to a constant flow infusion with real-time IOP monitoring. Large scleral flaps (4 x 4 mm, 16 mm(2), ...
Agar, Ashish
Cellular responses to changes in pressure are implicated in numerous disease processes. In glaucoma apoptosis of retinal ganglion cells (RGCs) is associated with elevated intra-ocular pressure (IOP), however the exact cellular basis of this link remains unclear. This research aimed to examine the direct response of neuronal cells to elevated ...
Kondo Nobuhiko - - 2006
PURPOSE: The amount of intraocular pressure (IOP) reduction achieved by the use of latanoprost eyedrops varies among patients, and there are even nonresponders. This report examines whether there is any correlation between the amount of individual variability in IOP reduction and the uveoscleral outflow facility after latanoprost eyedrop instillation in ...
Van de Veire S - - 2006
PURPOSE: To compare conventional argon laser trabeculoplasty (ALT) with selective laser trabeculoplasty (SLT) in terms of their efficiency in lowering the intra-ocular pressure. METHODS: In this retrospective study, 56 eyes from 44 patients with primary open angle glaucoma, ocular hypertension, pseudo-exfoliative (PXF) or pigment dispersion glaucoma (PDG) were included. Patients ...
Martínez Antonio - - 2006
OBJECTIVE: To assess the effects of dorzolamide/timolol fixed combination (DTFC) and latanoprost 0.005% on the retrobulbar haemodynamics and intraocular pressure (IOP) of open-angle glaucoma patients. METHODS: 22 consecutive subjects with newly diagnosed, open-angle glaucoma were included in this prospective, examiner masked, randomized, crossover study. The patients were randomized into two ...
Hariprasad Seenu M - - 2006
PURPOSE: To report the changes and trends in intraocular pressures (IOP) following intravitreal injection of Pegaptanib (Macugen) for the treatment of exudative age-related macular degeneration. DESIGN: Retrospective chart review. METHODS: Review of 79 patients who underwent 122 consecutive Pegaptanib injections. Analysis of the short-term effect of Pegaptanib injections on IOP ...
Caça Ihsan - - 2006
We compared latanoprost monotherapy therapy with timolol/ dorzolamide in patients with primary open-angle glaucoma to evaluate the effects on intraocular pressure (IOP) and occurrence of adverse events. IOP and topical side effects were evaluated at the beginning, first, and third months. Mean IOP was decreased at the third month. The ...
Brittain Christopher J - - 2006
This prospective study compared intraocular pressure (IOP) control, cardiorespiratory function, and adverse effects in 50 patients with glaucoma and ocular hypertension. Patients on topical combination timolol-latanoprost therapy were recruited. After they had used this combination for at least 2 months, they were switched to bimatoprost monotherapy. Full ocular examination and ...
Sullivan Stephen R - - 2006
BACKGROUND: Fluid resuscitation remains a fundamental component of early burn care management. However, recent studies suggest that excessive volumes of resuscitation are being administered. Overresuscitation results in negative sequelae including abdominal and extremity compartment syndromes. Elevated intraocular pressure (IOP) has been described as another potentially devastating effect of massive fluid ...
Frampton James E - - 2006
A fixed combination of brimonidine (a highly selective alpha(2)-adrenergic agonist) and timolol (a non-selective beta-blocker) [brimonidine 0.2%/timolol 0.5% ophthalmic solution; brimonidine/timolol] is available for the topical treatment of glaucoma and ocular hypertension (OH). Brimonidine and timolol decrease elevated intraocular pressure (IOP) by complementary mechanisms of action and have an additive ...
Sunwoo Yujin - - 2006
In order to investigate the influence of low relative humidity, we measured saccharin clearance time (SCT), frequency of blinking, heart rate (HR), blood pressure, hydration state of skin, transepidermal water loss (TEWL), recovery sebum level and skin temperature as physiological responses. We asked subjects to judge thermal, dryness and comfort ...
Frenkel Shahar - - 2006
Four masked examiners studied the usefulness of the glass-rod for estimating intraocular pressure (IOP) in a living, anesthetized rabbit eye manometrically set to 135 different random values. With training, the average error in IOP estimation improved from 7.42 +/- 5.56 mmHg to 5.13 +/- 4.48 mmHg. Gentle palpation of the ...
Parmaksiz S - - 2006
PURPOSE: To compare the intraocular pressure (IOP) lowering effect and safety of latanoprost, travoprost given every evening, and the fixed combination dorzolamide + timolol (DTFC) given twice daily in pseudoexfoliation glaucoma (PXG). METHODS: This randomized, prospective, investigator-masked study has been conducted with 50 PXG patients. Patients were assigned to one ...
Frampton James E - - 2006
Topically administered dorzolamide 2%/timolol 0.5% (dorzolamide/timolol ophthalmic solution; Cosopt) is a fixed combination of two ocular hypotensive drugs (the carbonic anhydrase inhibitor dorzolamide and the beta-adrenoceptor antagonist timolol) that have an additive effect on lowering intraocular pressure (IOP) when administered together. This product is indicated for the treatment of elevated ...
Erkin Esin F - - 2006
AIMS: To investigate the cardiovascular and respiratory effects of topical latanoprost 0.005% and topical betaxolol 0.25% monotherapy in newly diagnosed glaucoma patients. METHODS: Fortynewly diagnosed glaucoma patients were enrolled in this prospective, observer-masked, randomized, parallel study. Patients received either latanoprost 0.005% or betaxolol 0.25% for a duration of 3 months. ...
Sadaba Luis M - - 2006
BACKGROUND: Nonarteritic ischemic optic neuropathy affects the anterior portion of the optic nerve and is characterized by sudden, painless visual loss. The affected eye has a relative afferent pupillary defect. The typical funduscopic appearance includes optic disc edema, with associated nerve fiber layer hemorrhage. Risk factors include advanced age, systemic ...
Gupta Vinod Kumar - - 2006
The association between systemic hypertension and headache remains controversial and its pathophysiologic basis is uncertain. A rather characteristic early-morning pulsating headache is commonly seen in hypertensive patients, and a recent meta-analysis supports the link between these 2 entities. Epidemiologic evidence has paradoxically suggested a negative association between hypertension and headache. ...
Fogagnolo P - - 2006
To analyse 24 hour variations in intraocular pressure (IOP) and central corneal thickness (CCT) in a group of glaucomatous patients. 30 patients with primary open angle glaucoma were hospitalised and underwent circadian evaluations (at 8 pm, midnight, 4 am, 8 am, noon, and 4 pm) of supine and sitting IOP, ...
Kim Min-Su - - 2005
The effect of acupuncture on intraocular pressure (IOP) was evaluated in normal dogs. After determination of baseline pressure, acupuncture was applied at 3 acupoints (LI-4, LIV-3 and GB-37) for 20 min. After acupuncture treatment, IOP were significantly lowered 2.7 +/- 0.1 in left eye, 1.7 +/- 0.7 in right eye, ...
Paques Michel - - 2005
PURPOSE: This study explored the causes of vision fluctuations in patients with chronic macular edema. METHODS: Fifteen patients (16 eyes) with vision blurring at awakening due to post-central retinal vein occlusion (CRVO) macular edema underwent three examination sessions over 24 hours (at 7 PM, immediately after awakening at 7 AM, ...
Talty Patrick - - 2005
PURPOSE: To investigate the effect that extended wear of a tight necktie has on the intraocular pressure (IOP), measured by Goldmann applanation tonometry in a normal and aged-matched glaucoma group. METHODS: One eye of 18 normal and 19 primary open-angle glaucoma patients was included in this prospective study. The intraocular ...
Dawson William W - - 2005
PURPOSE: To compare repeat-sample means variance of laser induced ocular hypertension (OH) in rhesus monkeys with the repeat-sample mean variance of natural OH in age-range matched monkeys of similar and dissimilar pedigrees. MATERIALS & METHODS: Multiple monocular, retrospective, intraocular pressure (IOP) measures were recorded repeatedly during a short sampling interval ...
Chandrasekaran Sujatha - - 2005
PURPOSE: To examine the relationship between coffee and caffeine intakes and intraocular pressure (IOP). MATERIALS AND METHODS: The Blue Mountains Eye Study examined 3654 participants aged 49+ years in an area west of Sydney, Australia. A detailed medical history questionnaire included average daily intakes of coffee and tea. The eye ...
Uusitalo Hannu - - 2005
PURPOSE: The objective of this randomized, double-blind, controlled crossover trial was to compare 0.1% timolol hydrogel formulation eyedrops with 0.5% timolol aqueous solution in terms of systemic effects, hypotensive efficacy and pharmacodynamics. METHODS: Twenty-four healthy subjects underwent careful ocular, cardiovascular and pulmonary function evaluation before and after 2 weeks of ...
Quigley H A - - 2005
During the last 30 years, the definition of glaucoma as been revised to eliminate the inclusion of intraocular pressure. Open angle glaucoma is the second leading cause of blindness in the world, but the proportion of those with the disease who become blind is low. Diagnostic methods for glaucoma need ...
Sehi Mitra - - 2005
PURPOSE: To examine the impact of diurnal variation in intraocular pressure (IOP) and mean ocular perfusion pressure (MOPP) on the variation in anterior optic nerve capillary blood flow (BF) in patients with untreated early primary open-angle glaucoma (uPOAG) and healthy volunteers. METHODS: Fourteen patients with uPOAG (age, 56.3 +/- 12 ...
Levy J - - 2005
OBJECTIVES: Although several works in the past have examined the effect of haemodialysis (HD) on intraocular pressure (IOP), reported findings, theories, and conclusions are very different. The objectives of this article are to resume the reported evidence of IOP changes during HD, to review the proposed hypothesis of HD influence ...
Akarsu C - - 2005
PURPOSE: To evaluate the cerebral haemodynamics in patients with pseudoexfoliation glaucoma. METHODS: A total of 19 consecutive patients with pseudoexfoliation glaucoma and 19 age- and sex-matched healthy volunteers were recruited in a prospective comparative study. The affected eye in patients with unilateral glaucoma and the eye with more advanced lesions ...
Gabelt B'Ann T BT Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53792-3220, USA. - - 2005
To determine the effects of R-DOI, a selective 5-HT2 agonist, on intraocular pressure (IOP) and aqueous humor dynamics in monkeys. Normotensive cynomolgus monkeys (n = 8) were treated topically once daily with four 5-muL drops of 0.5% R-DOI in one eye, vehicle in the opposite eye. The 6-hour IOP response ...
Hosseini A - - 2006
Glaucoma, one of the leading causes of blindness, is associated with high intraocular pressure (IOP) as a risk factor. The aim of this study was to examine both local and systemic effects of chronic topical administration of the synthetic CB1/CB2 agonist, WIN-55-212-2 and its potential to sustain ocular hypotension. WIN-55-212-2 ...
Orihashi Masahiro - - 2005
PURPOSE: To compare the ocular hypotensive effect of nipradilol and timolol in combination with bunazosin in rabbits. METHODS: The intraocular pressure (IOP) in normal rabbits was measured using an applanation pneumatonograph. Nipradilol, timolol, and bunazosin were instilled, individually or in combination, into the inferior conjunctival sac. RESULTS: Nipradilol (0.25%), timolol ...
Selbach J Michael - - 2005
The aim of this prospective study was to investigate episcleral venous pressure (EVP) in different forms of glaucoma in comparison with age-matched controls. EVP was measured by means of a venomanometer in 32 eyes with untreated primary open-angle glaucoma (POAG), 36 eyes with untreated normal-tension glaucoma (NTG) as well as ...
Orgul Selim - - 2005
Treatment of normal-tension glaucoma has been a subject of debate for several years. Glaucomatous damage cannot be influenced directly, and current treatment modalities in normal-tension glaucoma are aimed at the control of risk factors. Intraocular pressure is a widely accepted risk factor and its reduction can improve the prognosis in ...
Moorhead Louise C - - 2005
OBJECTIVES: To directly measure dynamic intraocular pressure (IOP) during vitrectomy and to determine whether disposable pressure transducers placed in the infusion line can indirectly measure with accuracy the dynamic IOP during vitrectomy. METHODS: Experimental clinical study of 10 patients undergoing vitrectomy. Dynamic IOP was sampled via an extra pars plana ...
Leelachaikul Yupin - - 2005
OBJECTIVES: To assess the efficacy and safety of unoprostone isopropyl as an adjunctive treatment to topical beta-blocker in patients with primary open angle glaucoma (POAG). STUDY DESIGN: This was a prospective, open-label clinical study. MATERIAL AND METHOD: A total of 44 eyes of 22 eligible patients whose intraocular pressure (IOP) ...
Bui Christina M - - 2005
BACKGROUND: Topical, intraocular, oral, and parenteral steroids might increase intraocular pressure (IOP), but little is known regarding the effect of nasal steroid spray. OBJECTIVE: We sought to examine the effect of discontinuing nasal steroid sprays on IOP in patients with glaucoma. METHODS: A retrospective chart review of patients with glaucoma ...
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