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Hernández-Verdejo José Luis - - 2010
To simultaneously measure, using manometry, the changes of intraocular pressure (IOP) in the anterior chamber and in the vitreous cavity of a single porcine eye, induced by an external column of water. We prospectively measured IOP simultaneously in seven freshly enucleated porcine eyes in both the anterior chamber and the ...
Schiano Lomoriello Domenico - - 2011
To examine the repeatability of intra-ocular pressure (IOP) and central corneal thickness (CCT) measurements provided by the Tono-Pachymeter NT530P (Nidek, Japan), and to assess agreement of the device with Goldmann applanation tonometry (GAT) and ultrasound pachymetry (UP). Sixty-two normal eyes of 62 subjects were included in the study. Three sessions ...
Božić Marija - - 2010
Purpose: Vascular dysregulation is deemed a significant risk factor in glaucoma occurrence and progression. Capillaroscopy of the blood vessels on the finger nail-fold is a method that can provide information regarding the state of the vascular system at the capillary level. The aim of this pilot study was to determine ...
Pépin Jean-Louis - - 2010
OBJECTIVE: To assess 24-hour intraocular pressure (IOP) and ocular perfusion pressure rhythms in newly diagnosed apneic patients before and after nasal continuous positive airway pressure (nCPAP) treatment. METHODS: Intraocular pressure (using a Tonopen XL) and ambulatory blood pressure, measured hourly for 24 hours, were analyzed in 18 consecutive patients with ...
Myers Kristin M - - 2010
The purpose of this research was to develop a reliable and repeatable inflation protocol to measure the scleral inflation response of mouse eyes to elevations in intraocular pressure (IOP), comparing the inflation response exhibited by the sclera of younger and older C57BL/6 mice. Whole, enucleated eyes from younger (2 month) ...
Muttuvelu Danson V - - 2012
Purpose:  The purpose of this study was to evaluate the ICare tonometers precision and accuracy and the extent to which intraocular pressure (IOP) measurements are influenced by measuring position. Methods:  This was carried out by comparing the central and peripheral ICare-IOP readings and comparing ICare- with the Goldmann applanation tonometer ...
Reuter Anne - - 2010
To examine the accuracy and reproducibility of intraocular pressure (IOP) measurements obtained by the TonoVet rebound tonometer. Animals studied  Freshly enucleated healthy eyes of 44 free-ranging birds of prey out of the species Haliaeetus albicilla, Accipiter gentilis, Accipiter nisus, Buteo buteo, Falco tinnunculus, Strix aluco, Asio otus and Tyto alba euthanized because of unrelated health problems. IOP readings ...
Govêia Catia Sousa CS Faculdade de Medicina da Universidade de Brasília. - - 2010
Peribulbar anesthesia can reduce ocular blood flow (OBF) by increasing intraocular pressure (IOP) or due to the action of drugs. Ropivacaine has low toxicity and intrinsic vasoconstrictive properties, yet to be proven on the ocular vasculature. Measurements of ocular pulse amplitude (OPA) allow the indirect evaluation of the OBF. The ...
Wax Martin B - - 2011
Although the majority of patients with glaucoma have elevated intraocular pressure as the presumed etiology for their resultant neuropathy, it is well known that approximately 25% of patients with glaucoma have intraocular pressure within the normal range for their race. These patients may have conditions that facilitate non-pressure related stress ...
Leung Dexter Y L - - 2011
Background It has been shown that the pressure-to-cornea index (PCI), which estimates the relative effects of intraocular pressure (IOP) and central corneal thickness (CCT), may differentiate between glaucoma and non-glaucoma states. The authors investigated the utility of the pressure-cornea-vascular index (PCVI) in predicting field-progression in patients with normal tension glaucoma ...
Fogagnolo Paolo - - 2010
PURPOSE: To evaluate the influence of central corneal thickness (CCT) and its 24-hour fluctuation on 24-hour intraocular pressure (IOP) fluctuation in primary open-angle glaucoma. METHODS: Forty consecutive patients underwent 24-hour evaluation (8 PM, midnight, 4 AM, 8 AM, noon, and 4 PM) of supine and sitting IOP, measured with handheld ...
Johnson Thomas V - - 2010
PURPOSE: To investigate whether the intraocular pressure (IOP) reduction and mechanism of action of timolol and latanoprost change between 1 and 6 weeks of treatment. PATIENTS AND METHODS: Thirty participants on no ocular medications completed this double-masked, 6-visit, crossover study. At each visit IOP was determined by pneumatonometry, aqueous flow ...
Konstas A G P - - 2010
To evaluate 24-h efficacy of travoprost/timolol fixed combination (TTFC) vslatanoprost/timolol fixed combination (LTFC) in exfoliative glaucoma (XFG). A prospective, single-masked, crossover, active-controlled, randomized 24-h comparison. After up to a 6-week medicine-free period, XFG patients were randomized to either TTFC or LTFC for 3 months, dosed each evening, and then changed ...
McMonnies Charles W - - 2010
PURPOSE: To examine corneal responses to elevated intraocular pressure (IOP). METHODS: For a sample of 10 normal subjects, noncontact tonometry was used to measure IOP elevations in response to scleral indentation from a standardized ophthalmodynamometer (ODM) force. Using the same ODM force, corneal topography was assessed for the same controls ...
Ogbuehi Kelechi C - - 2010
PURPOSE: Comparison of the magnitude and repeatability of the intraocular pressure (IOP) measured with the Ocular Response Analyzer (ORA) to that measured with the Goldmann tonometer. METHODS: Two sets of IOP measurements were made, for 89 eyes of eighty-nine subjects, approximately 1-week apart. Goldmann tonometry was performed subsequent to non-contact ...
Muchnok Tim - - 2012
Handheld measurement of intraocular pressure (IOP) has been previously shown to accurately predict elevated intracranial pressure (ICP) in neurosurgical patients. Handheld tonometry may have clinical utility in the prediction of elevated ICP among a cohort of emergency department (ED) patients receiving lumbar puncture (LP). To ascertain the sensitivity and specificity ...
Fan Dorothy S P - - 2011
To study the accuracy and acceptability of intraocular pressure (IOP) measurement by the pressure phosphene tonometer, non-contact tonometer, and Goldmann tonometer in children. Fifty children (5 to 14 years old) participated in this prospective comparative study. IOP was measured with the pressure phosphene tonometer, non-contact tonometer, and Goldmann tonometer by ...
Stankiewicz Andrzej - - 2010
To assess the additive effect of dorzolamide hydrochloride 2% on the diurnal intraocular pressure (IOP) curve and retrobulbar haemodynamics in patients with primary open-angle glaucoma (POAG) treated with morning-dosed bimatoprost 0.03%. Twenty-five patients with POAG were evaluated in a prospective, single-masked study. After a 1 week run-in period with bimatoprost ...
Tomoyose Eriko - - 2010
PURPOSE: To examine the distribution of intraocular pressure (IOP) and its related systemic and ocular biometric factors in a population-based study in a southwestern island of Japan. DESIGN: Cross-sectional, population-based study. METHODS: All residents of Kumejima Island, Japan, located in southwestern Japan (eastern longitude, 126 degrees 48 minutes and northern ...
Gaton Dan D - - 2010
PURPOSE: To evaluate the stability of successive applanation tonometry measurements in glaucomatous eyes. METHODS: A prospective, comparative, randomized, and evaluator-masked study was conducted in a tertiary medical center. Sixty-seven patients with glaucoma attending our glaucoma clinic underwent four successive intraocular pressure (IOP) measurements with Goldmann-type applanation tonometry. Findings were compared ...
Hatanaka Marcelo - - 2010
PURPOSE: To evaluate the additive effect of dorzolamide/timolol fixed combination in patients under monotherapy with latanoprost. PATIENTS AND METHODS: In this prospective, 4-week, randomized, open-label controlled clinical trial, patients with open-angle glaucoma or ocular hypertension, which presented at least 15% intraocular pressure (IOP) reduction after a minimum period of 15 ...
Costa Vital P - - 2010
To compare the 24 h intraocular pressure (IOP), blood pressure (BP), and perfusion pressure (PP) of primary open-angle glaucoma (POAG) patients and healthy individuals. 24 healthy individuals and 29 POAG patients underwent IOP and BP measurements every 2 h, starting at 08:00 until 06:00 of the next morning. IOP measurements ...
Garc?a-Res?a Carlos - - 2010
PURPOSE: To assess the accuracy and repeatability of intraocular pressure (IOP) measurements obtained with the Canon TX-10 noncontact tonometer (NCT), using the Goldmann applanation tonometer (GAT) as the gold standard. METHODS: Seventy-three young healthy subjects were enrolled in the study. Central corneal thickness (CCT) was obtained with Orbscan Topography System ...
Cohan Bruce E - - 2010
A prototype device was developed for using the Goldmann applanation tonometer (GAT) without a slitlamp to make it potentially practical to measure intraocular pressure (IOP) away from the clinic. Inexpensive consumer video components and a small flashlight replaced the microscope and illuminator of the slitlamp in a device that was ...
Caprioli Joseph - - 2010
PURPOSE: To provide a critical review of the relationships between blood pressure, ocular blood flow, and glaucoma and the potential for glaucoma treatment through modulation of ocular perfusion. DESIGN: Summaries of the pertinent literature and input from glaucoma researchers and specialists with relevant experience. METHODS: Review and interpretation of selected ...
Karadag Remzi - - 2010
To ascertain whether the changes in intraocular pressure (IOP) that occur during hypobaric hypoxic exposure are related to plasma N-terminal pro-brain natriuretic peptide (BNP) levels. The study group comprised 26 healthy participants (all male, mean age 23.1 years). IOP was measured at local ground level, (792 m above sea level), ...
Eliahu Shay - - 2010
Extracellular nucleotides can modify the production or drainage of the aqueous humor via activation of P2 receptors and therefore affect the intraocular pressure (IOP). We have synthesized slowly hydrolyzable nucleoside di- and triphosphate analogues, 1, and 8-14. Analogues 8-14 were completely resistant to hydrolysis by alkaline phosphatase over 30 min ...
Haefliger I O - - 2010
BACKGROUND: The aim of this study was to assess the pathophysiological mechanisms leading to intraocular pressure (IOP) increase and to review the prevalence of glaucoma in thyroid eye disease (TED), an autoimmune reaction affecting extra-ocular muscles and intra-orbital content in thyrotoxicosis (Grave's disease, hyperthyroidism). MATERIAL AND METHODS: We applied the ...
Lam Andrew K C - - 2010
PURPOSE: To determine the influence of refractive surgery on intraocular pressure (IOP) measurements obtained using an iCare rebound tonometer and a Goldmann applanation tonometer. SETTING: School of Optometry, Hong Kong Polytechnic University, Hong Kong, China. METHODS: Intraocular pressure was measured using the rebound tonometer and applanation tonometer before and 1 ...
Xu Xin - - 2010
Myopic eyes show structural differences from normal eyes and may respond differently to microgravity, increasing the risk for possible development of ocular hypertension and glaucoma on orbit. In this experiment we used head-down rest (HDR) at an angle of 15 degrees to produce hydrostatic changes similar to acute exposure to ...
Borghi Valentina - - 2010
PURPOSE: Nitric oxide (NO) is involved in a variety of physiological processes including ocular aqueous humor dynamics by targeting mechanisms that are complementary to those of prostaglandins. Here, we have characterized a newly synthesized compound, NCX 125, comprising latanoprost acid and NO-donating moieties. METHODS: NCX 125 was synthesized and tested ...
Zhang Yu-Zhong - - 2010
Motivated by recent experimental measurements on pressure-driven phase transitions in Mott insulators as well as the new iron pnictide superconductors, we show that first principles Car-Parrinello molecular dynamics calculations are a powerful method to describe the microscopic origin of such transitions. We present results for (i) the pressure-induced insulator to ...
Heijl Anders - - 2011
To evaluate: (i) the relationship between intraocular pressure (IOP) reduction attained with a fixed treatment protocol and the untreated IOP level; (ii) the consistency of IOP reduction over time; and (iii) whether there is a threshold pretreatment IOP level below which IOP reduction might be less effective. Results are based ...
Sanz Silvia - - 2010
Acute angle closure glaucoma is an ocular pathology characterized by a severe increase of intraocular pressure (IOP) that requires the realization of a peripheral Nd:YAG laser iridotomy as a treatment. Several complications have been described after a peripheral laser iridotomy such as hyphema, endothelial corneal damage, intraocular pressure spikes or ...
Meira-Freitas Daniel - - 2010
PURPOSE: To evaluate the short-term effect of acupuncture on the intraocular pressure (IOP) in healthy subjects. METHODS: A randomised controlled double-blinded trial was performed. 48 healthy volunteers (94 eyes) were randomly allocated to three groups: acupuncture group-19 subjects (38 eyes) were submitted to a 20 min session of acupuncture (GB1, ...
Nakamoto Kenji - - 2010
PURPOSE: To evaluate the effects of carteolol hydrochloride (carteolol) on 24-h variations in intraocular pressure (IOP) in patients with normal-tension glaucoma (NTG). METHODS: Twelve patients with NTG were treated with carteolol 2% solution for >or=8 weeks; their pretreatment 24-h IOP variations, blood pressure (BP), and pulse rate (PR) were compared ...
Park Sang-shin - - 2010
OBJECTIVES: The current study was performed to assess the distribution of intraocular pressure (IOP) and its association with metabolic syndrome (MS) in a community. METHODS: We measured IOP and MS components from 446 adults, age 20 or more years old, who reside in a community in Kyunggi Province, South Korea. ...
Zheng Yingfeng - - 2010
PURPOSE. To describe the distribution of ocular perfusion pressure and its relationship with open-angle glaucoma (OAG) in a Malay population. METHODS. This was a population-based, cross-sectional study comprising 3280 (78.7% response) ethnic Malays. Intraocular pressure (IOP) was measured with Goldmann applanation tonometry. Systolic and diastolic blood pressure (SBP and DBP) ...
Kotecha Aachal - - 2010
OBJECTIVE: To examine the repeatability and reproducibility of intraocular pressure (IOP) measurements obtained with the Goldmann applanation tonometer (GAT), the Pascal dynamic contour tonometer (DCT; Swiss Microtechnology AG, Port, Switzerland), and the Reichert Ocular Response Analyzer (ORA; Reichert Ophthalmic Instruments, Buffalo, NY). A secondary objective was to assess agreement between ...
Morgan William H - - 2010
BACKGROUND: Ophthalmodynamometric studies can provide useful clinical information regarding glaucoma, cerebrospinal fluid pressure, and vascular disease but are affected by variable reproducibility and unknown calibration of force in terms of intraocular pressure (IOP). The aim of this study was to calculate calibration factors and identify key design principles using three ...
Memarzadeh Farnaz - - 2010
To examine the cross-sectional relationship between blood pressure, perfusion pressure, and prevalence of open angle glaucoma (OAG) in an adult Latino population. Participants aged 40 years and older (N = 6130) from the Los Angeles Latino Eye Study (LALES), a large, population-based study of self-identified adult Latinos, underwent an interviewer-administered ...
Wostyn Peter - - 2010
In a 1994 Medical Hypotheses paper, it was speculated that high intracranial pressure (ICP) might increase the probability of developing Alzheimer's disease (AD). A study of cerebrospinal fluid pressure (CSFP) in normal volunteers showed interindividual variations in CSFP. Some normals had what would normally be considered elevated CSFP. The hypothesis ...
Jorge J - - 2010
This study proposes to evaluate the level of accuracy of intraocular pressure (IOP) measurements of a second generation rebound tonometer (IOPen, taking as references the Goldmann Applanation Tonometer (GAT) and the iCare rebound tonometer. The right eyes of 101 consecutive clinical patients were assessed with the three tonometers. The IOPen ...
Salman Zeena - - 2010
Cardiovascular disease (CVD) frequently has roots in childhood, including following childhood-onset hypertension. Incidence of CVD has increased in developing countries in East Africa during recent urbanization. Effects of these shifts on childhood hypertension are unclear. Our objectives were to (1) Determine the prevalence of hypertension among primary schoolchildren in Khartoum, ...
Kreutzer Thomas C - - 2010
PURPOSE: To evaluate intraocular pressure (IOP) in the vitreous cavity during various stages of cataract surgery. SETTING: University Eye Hospital, Ludwig-Maximilians University, Munich, Germany. METHODS: In consecutive eyes having combined phacoemulsification, intraocular lens implantation, and pars plana vitrectomy, IOP was monitored in real time through a 25-gauge pars plana cannula ...
Pescosolido N - - 2010
Background/Aims. Control of intraocular pressure is still the main strategy to treat glaucoma patients. Forskolin has already shown an ability to control intraocular pressure after topic administration, whereas rutin is known to improve ocular blood fl ow. Therefore, aim of this pilot study has been to observe whether administration of ...
Scardillo Alessio - - 2010
The goal of glaucoma management is to reduce intraocular pressure (IOP) and maintain it at a level compatible with the health of the optic nerve. New therapies are constantly being sought. Topical instillation of levobunolol 0.5%, alone or with dorzolamide 2%, has a hypotensive effect on the IOP in healthy ...
Suzuki Emilio Rintaro ER - - 2010
Travoprost is a prostaglandin analog used in the management of glaucoma and ocular hypertension for reducing intraocular pressure (IOP). The IOP-lowering efficacy of travoprost has been shown to be similar to that of other prostaglandins, including latanoprost and bimatoprost. When compared with fixed combinations of timolol and either latanoprost or ...
Pozarowska Dorota - - 2010
Glaucoma is one of the most common neuropathies of the optic nerve. An elevated intraocular pressure (IOP) is a well documented risk factor for the development and progression of this disease. Until now, IOP reduction is the only well documented successful method of glaucoma treatment. Among the many hypotensive drugs, ...
Lee Anne J - - 2010
Prostaglandin analogs (PGA) are powerful topical ocular hypotensive agents available for the treatment of elevated intraocular pressure (IOP). Latanoprost 0.005% and travoprost 0.004% are prodrugs and analogs of prostaglandin F2alpha. Bimatoprost 0.03% is regarded as a prostamide, and debate continues as to whether it is a prodrug. The free acids ...
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