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Gepner Adam D AD From the University of Wisconsin School of Medicine and Public Health, Madison, WI (A.D.G., C.E.K., J.H.S.); Northwestern University Feinberg School of Medicine, Chicago, IL (L.A.C., K.L.); University of Washington School of Public Health, Seattle (M.B., I.H.d.B., B.K., D.S.S., J.D.K.); and Department of Medicine, Geneva University Hospitals, Switzerland - - 2014
To evaluate the impact of vitamin D and parathyroid hormone (PTH) on longitudinal changes in arterial stiffness. Distensibility coefficient and Young's elastic modulus of the right common carotid artery were evaluated at baseline and after a mean (SD) of 9.4 (0.5) years in 2580 Multi-Ethnic Study of Atherosclerosis (MESA) participants. ...
Rafieian-Kopaei Mahmoud - - 2014
This study was conducted to investigate the association between serum uric acid level and blood pressure in type 2 diabetes mellitus. Sixty patients with type 2 diabetes mellitus were enrolled to the study. None of the patients had a history of gout, were treated with allopurinol, or were treated with ...
Mateus-Hamdan L L C. Annweiler, MD, PhD, Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital, 49933 Angers Cedex 9, France; E-mail: CeAnnweiler@chu-angers.fr; Phone: ++33 2 41 35 54 86; Fax: ++33 2 41 35 48 - - 2014
Objective: High arterial pulse pressure is a predictor of cardiovascular morbimortality. Mineral metabolism has been associated with blood pressure regulation. Our objective was to determine which variable among serum calcium, parathyroid hormone and 25-hydroxyvitamin D concentrations, was associated with pulse pressure among older adults. Design: Cross-sectional study corresponding to the ...
Nasri Hamid H Department of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences, Isfahan, - - 2014
Background: Vitamin D is an important mediator of calcium metabolism. It has also been implicated as a potential contributor to the pathophysiology of various extra-skeletal conditions, consisting hypertension, renal disease, and insulin resistance.Objectives: The primary objective of this study was to determine whether oral vitamin D (cholecalciferol) supplementation can lead ...
Behradmanesh Saeed S Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, - - 2013
Introduction: Hypertension and diabetes are two common diseases and they affect the same major target organs. Objectives: In this study, we sought to investigate the probable association of serum calcium with levels of systolic and blood pressure in a group of type 2 diabetic (T2D) patients. Patients and Methods: A ...
Shih Chia-Jen - - 2013
Background: Secondary hyperparathyroidism is associated with vascular calcification and arterial stiffness in patients with end-stage renal disease. The aim of this study was to analyze the frequency of intradialytic hypotension (IDH) and cardiovascular function before and after parathyroidectomy (PTX) in maintenance hemodialysis patients. Methods: We compared predialytic and intradialytic blood ...
Sun Hao - - 2013
Calcium plays an important role in regulating body homeostasis. Several studies have reported the association between serum calcium and cardiovascular disease in adults. However, studies assessing the relationship between serum calcium and hypertension were limited, especially in subject populations of adolescents. The aim of the present study was to examine ...
Derosa Giuseppe - - 2013
This study aims to evaluate the effects of an angiotensin receptor blocker (ARB)/calcium channel blocker combination on blood pressure control, lipid profile, insulin sensitivity, and inflammation markers. We randomized 276 hypertensive patients to olmesartan 20 mg, amlodipine 10 mg, or a single pill containing an olmesartan/amlodipine combination 20/5 mg for 12 months. We evaluated ...
Garcia Vivian Cristina - - 2013
The aim of the present study was to evaluate whether vitamin D status is related to blood pressure (BP) in adults. We evaluated the relationship between vitamin D status, intact parathyroid hormone (iPTH) and BP in 332 adults. Anthropometric measurements, BP, and a fasting blood sample was obtained. Participants were ...
Chai Weiwen - - 2013
To estimate the effects of calcium or vitamin D supplementation or a combination of both on blood pressure and serum lipid and carotenoid levels. Ninety-two colorectal adenoma patients were randomized in a pilot, double-blind, placebo-controlled clinical trial of supplemental vitamin D3 800 IU and elemental calcium 2.0 g (as calcium ...
Oshikawa Jin - - 2013
Abstract Diuretics or calcium channel blockers (CCBs) are used concomitantly with an angiotensin II receptor blocker (ARB). However, it is not established which ARB-based combination therapy is the most effective and safe. This prospective randomized open-label study compared the efficacy and safety of a fixed-dose tablet of losartan (LST)-hydrochlorothiazide (HCTZ) ...
Kulo─člu Osman - - 2013
Vitamin D may modulate vascular inflammation, vascular smooth muscle cell proliferation, the renin-angiotensin system, and cardiomyocyte proliferation, myocardial fibrosis, and proliferation. These mechanisms may play a role on arterial stiffness and left ventricle hypertrophy (LVH) in hypertensive patients. We aimed to evaluate the association between serum vitamin D with arterial ...
Ulu Sena Memnune - - 2013
Abstract Introduction and objective: In this study, we aimed to investigate the relationship between vitamin D, parathyroid hormone (PTH) and cardiovascular risk (CVR) in hypertensive patients aged 65 years and over. Patients and methods: This study was performed with 84 hypertensive patients and 68 normotensive control group in Afyon Kocatepe ...
Bosworth Cortney C Division of Nephrology and Kidney Research Institute, Department of Medicine, University of Washington, Seattle, WA, - - 2013
High circulating concentrations of parathyroid hormone (PTH) have been associated with increased risks of hypertension, left ventricular hypertrophy, congestive heart failure and cardiovascular mortality. Impaired arterial function is a potential mechanism for these associations. We tested whether serum PTH concentration is associated with measures of arterial function. Cross-sectional study. A ...
Corona E - - 2013
Ultrasonic measurements were used to characterize the effect of high pressure treatment (HPT) (600MPa/6min) or cold storage (6°C/120days) on the textural properties of vacuum packaged dry-cured ham. The ultrasonic velocity, textural properties and fat content were determined in the ham packages. The ultrasonic velocity was related to the ham hardness, ...
Oliveira Pedro - - 2013
Introduction: In tissues and organs exposed to large pressure amplitude low frequency noise fibrosis occurs in the absence of inflammatory signs, which is thought to be a protective response. In the parotid gland the perivasculo-ductal connective tissue surrounds arteries, veins and the ductal tree. Perivasculo-ductal connective tissue is believed to ...
Yao Yingshui - - 2013
Previous studies revealed that low calcium intake is related to high prevalence of cardiovascular diseases such as hypertension. However, the relationship between serum calcium and blood pressure was unclear. The prevalence of hypertension is high in China. Thus, the aim of this study was to evaluate the serum calcium level ...
Kim Mi-Hyun - - 2012
Several studies revealed that low calcium intake is related to high prevalence of cardiovascular diseases such as hypertension. The prevalence of hypertension is high in Koreans along with their low dietary calcium consumption. Thus, the aim of this study was to evaluate the status of calcium intake between the hypertension ...
Sabino-Silva Robinson - - 2012
Salivary gland function is regulated by both the sympathetic and parasympathetic nervous systems. Previously we showed that the basal sympathetic outflow to the salivary glands (SNA(SG)) was higher in hypertensive compared to normotensive rats and that diabetes reduced SNA(SG) discharge at both strains. In the present study we sought to ...
Mateus-Hamdan Leyla - - 2012
Aim:  Serum parathyroid hormone (PTH) and 25-hydroxyvitamin D (25OHD) concentrations might contribute to blood pressure (BP) levels. Mixed results in previous literature could be due to the failure to consider both these hormones concurrently, despite their long-known relationship. Our objective was to examine the association of serum intact PTH and ...
Dongre Nilima N NN Department of Biochemistry, BLDEU's Shri B.M.Patil Medical College, Bijapur, Karnataka 586 103 - - 2013
Lead is one of the most widely scattered toxic metals in the environment and used by mankind for over 9,000 years. Lead in the environment may be derived from natural or anthropogenic sources. In humans, lead can cause a wide range of biological effects depending upon the level and duration of ...
Lim Kyungjoon - - 2012
Methodological improvements in measuring cardiovascular parameters have meant that data can be collected from freely moving animals in their home cage. However, experiments in rabbits still often require them to be restrained in a laboratory setting. The aim of this study was to determine whether measurements collected when the rabbits ...
Labet Vanessa - - 2012
In the first of a series of four papers on hydrogen under pressure, and its transitions from an initiating molecular state, we begin by defining carefully the problem, and setting the distance scale of interactions of protons and electrons in molecular aggregates of the first of the elements. Following a ...
Creaven Ann-Marie - - 2012
While perceived social support appears to be associated with buffered cardiovascular reactivity to short-term stressors, its impact on cardiovascular recovery is less clear. This relationship might be affected by trait hostility, with hostile individuals benefiting less from social support. However, despite the possibility that support provision might enhance well-being, limited ...
Li Lihua - - 2012
Conflicting reports support or refute an association between vitamin D deficiency with high levels of parathyroid hormone (PTH) and raised blood pressure or hypertension. To explore the associations of serum vitamin D and PTH levels with blood pressure and risk of hypertension in a Chinese population. A population-based cross-sectional study ...
Onyesom I - - 2011
A total of seventy (70) consenting subjects were recruited for this study. The subjects consist of fifty (50) hypertensive subjects yet to receive treatment and twenty (20) normotensive (control) subjects. Subjects' blood pressure values were measured and serum was obtained from the whole blood collected by vene puncture using centrifugation ...
Ghuneim Wael Aly - - 2011
Abstract This study is a phase of biomechanical study; a part of research program concerned with the new concept of in situ tooth replication. The purpose of the study was to evaluate tooth replica under each of two possible circumstances: 1) attachment via periodontal ligament and 2) osseointegration. Replicas were ...
Kato Norihiro - - 2011
We conducted a meta-analysis of genome-wide association studies of systolic (SBP) and diastolic (DBP) blood pressure in 19,608 subjects of east Asian ancestry from the AGEN-BP consortium followed up with de novo genotyping (n = 10,518) and further replication (n = 20,247) in east Asian samples. We identified genome-wide significant ...
Nagai Michiaki - - 2011
Recently, visit-to-visit variability in systolic blood pressure (SBP) has been shown to be a predictor of stroke. In this study, we investigated the relationship of visit-to-visit blood pressure (BP) variations (based on 12 visits once a month) with intima-media thickness (IMT) and stiffness in common carotid artery among the 201 ...
Aybal Kutlugün Aysun - - 2011
Objective. This study examined the effects of low dialysate sodium on endothelial dysfunction (ED) as measured by flow-mediated dilatation (FMD) of brachial artery in haemodialysis (HD) patients. METHODS: Thirty HD patients (17 men; mean age: 48.4 ± 17.8 years) were studied. Subjects underwent two consecutive 6-week HD periods. Dialysate sodium ...
Raser Jonathan M - - 2011
BACKGROUND: Modifications to the age, blood pressure, clinical symptoms, duration of symptoms, and diabetes (ABCD(2)) score, which incorporate history of hypertension and acute hyperglycemia in addition to acute blood pressure (BP) elevation and history of diabetes, have been proposed to increase the predictive value of the score. In addition, the ...
Lilitkarntakul Pajaree P Clinical Pharmacology Unit, British Heart Foundation, Centre of Research Excellence, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, - - 2011
Patients with chronic kidney disease (CKD) have increased risk of cardiovascular disease to which co-morbidity and associated conventional risk factors contribute. We hypothesised that arterial stiffness (AS) and endothelial dysfunction (ED), as surrogates of cardiovascular risk, would worsen as renal function declined even in patients without co-morbidity and that this ...
Uemura Kazunori - - 2011
BACKGROUND: Peak systolic mitral annular velocity (S(m)) measured by tissue Doppler echocardiography has been recognized as an independent predictor of mortality in patients with heart failure and in the general population. However, the mechanical determinants of S(m) remain poorly defined. METHODS: A theoretical model of S(m) was derived, which indicates ...
Muntner Paul - - 2011
Recent data suggest that visit-to-visit variability of blood pressure is associated with stroke incidence. Correlates of increased visit-to-visit variability in blood pressure and the relationship between variability and all-cause mortality were examined using data on US adults ≥ 20 years of age from the Third National Health and Nutrition Examination ...
Riachy Moussa Albert - - 2011
A 30-year-old pregnant woman admitted to the hospital for rapidly progressive dyspnoea, non-productive cough and altered general status evolving over 1-month period. Her vital signs showed a low blood pressure 90/60 mm Hg, pulse rate 100 beats/min, respiratory rate 32 breaths/min and oxygen saturation on room air of 88%. Laboratory ...
Rich Shayna E - - 2011
Frequent manual repositioning is an established part of pressure ulcer prevention, but there is little evidence for its effectiveness. This study examined the association between repositioning and pressure ulcer incidence among bed-bound elderly hip fracture patients, using data from a 2004-2007 cohort study in nine Maryland and Pennsylvania hospitals. Eligible ...
Bonfiglio Andrea - - 2010
In this paper, we develop a mathematical model of blood circulation in the liver lobule. We aim to find the pressure and flux distributions within a liver lobule. We also investigate the effects of changes in pressure that occur following a resection of part of the liver, which often leads ...
Moore Christopher L - - 2010
The accurate noninvasive assessment of preload in emergency department (ED) patients remains elusive. Point-of-care ultrasound (US) imaging, particularly evaluation of the inferior vena cava (IVC), has been shown to be qualitatively helpful. Doppler and tissue Doppler are now routinely available on ED US equipment, but few studies have looked at ...
Zipprich A - - 2010
The hepatic venous pressure gradient (HVPG) is used as an estimation of portal pressure (PP) in the management of patients with cirrhosis. Two methods are available using either a straight or a balloon catheter, but have never been compared head-to-head. To compare the two methods of determining HVPG, straight and ...
Schmitt Françoise - - 2010
Lentiviral vectors can stably transduce hepatocytes and are promising tools for gene therapy of hepatic diseases. Although hepatocytes are accessible to blood-borne viral vectors through fenestrations of the hepatic endothelium, improved liver transduction after delivery of vectors to the blood stream is needed. As the normal endothelial fenestration and lentiviral ...
Kalambokis George - - 2010
Variceal bleeding in cirrhosis can cause liver ischaemia and deteriorate the hyperdynamic state; thus, the effects of vasoconstrictor therapy on liver blood volume (LBV) and thorax blood volume (ThBV) are important. To evaluate and compare the effects of terlipressin and somatostatin on LBV and ThBV in stable patients with cirrhosis ...
Laje Pablo - - 2010
We hypothesized that livers with biliary atresia (BA) are more susceptible to the harmful effects of a high-pressure CO(2) pneumoperitoneum (PP) than healthy livers. A murine model of BA was used in this experiment. Mice were divided into 6 groups: (1) control Balb/c; (2) control Balb/c, CO(2)-PP; (3) control BA; ...
Debbaut Charlotte - - 2011
Hypothermic machine perfusion (HMP) is experiencing a revival in organ preservation due to the limitations of static cold storage and the need for better preservation of expanded criteria donor organs. For livers, perfusion protocols are still poorly defined, and damage of sinusoidal endothelial cells and heterogeneous perfusion are concerns. In ...
Ikeda Osamu - - 2010
The aim of this study was to evaluate retrospectively the outcome of percutaneous transluminal venoplasty (PTV) after venous pressure measurement in patients with hepatic venous outflow obstruction following living donor liver transplantation (LDLT). We studied 24 consecutive patients suspected of having hepatic venous outflow obstruction after LDLT. Pressure gradients were ...
Khurana Sandeep - - 2010
The purpose of this study was to characterize changes in hepatic venous pressures in patients with chronic hepatitis C. The histology and laboratory data from patients with chronic hepatitis C who underwent a transjugular liver biopsy (TJLB) and hepatic venous pressure gradient measurement were analyzed. Portal hypertension was defined as ...
Chin J H - - 2010
We have described herein a 39-year-old male patient with hepatitis B virus-related cirrhosis (Child class C), showing a prolonged corrected QT interval, who developed torsades de pointes (TdP) in the neohepatic stage of liver transplantation (LT). There was no arrhythmia in the pre-anhepatic and anhepatic stages. Multiple premature ventricular complexes, ...
La Mura Vincenzo - - 2010
Hepatic venous pressure gradient (HVPG), the difference between wedge and free hepatic venous pressure, is the preferred method for estimating portal pressure. However, it has been suggested that hepatic atrial pressure gradient (HAPG)--the gradient between wedge hepatic venous pressure and right atrial pressure (RAP)--might better reflect variceal hemodynamics. The aim ...
Coelho-Prabhu Nayantara - - 2010
Portal hypertension is defined as an increase in hepatic sinusoidal pressure to 6 mm Hg or higher. Cirrhosis is the most common cause of portal hypertension in the western world and results from increased resistance to blood flow at the hepatic sinusoidal level.
Nelson Nathan C - - 2010
Determination of central venous pressure (CVP) is relevant to patients with right heart disease, hypovolemia, and following intravenous fluid therapy. We hypothesized that changes in CVP in dogs could be predicted by measurements of hepatic vein diameter, caudal vena cava (CVC) diameter, and hepatic venous flow velocities. Nine healthy American ...
Massicotte Luc - - 2010
BACKGROUND: A regimen of fluid restriction, phlebotomy, vasopressors, and strict, protocol-guided product replacement has been associated with low blood product use during orthotopic liver transplantation. However, the physiologic basis of this strategy remains unclear. We hypothesized that a reduction of intravascular volume by phlebotomy would cause a decrease in portal ...
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