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Carroll Douglas - - 2012
It has been argued recently that blunted cardiovascular reactions to acute psychological stress have adverse behavioural and health corollaries that reflect dysregulation of the neural systems that support motivation. We examined the association between cardiovascular reactions to a standard stress task, the paced auditory serial arithmetic rest, and forced expiratory ...
Shah Sovrin M - - 2012
Type III stress urinary incontinence (SUI) is generally defined as a condition that involves intrinsic sphincter deficiency (ISD). Although the clinical parameters for ISD are loosely defined as a Valsalva leak-point pressure <60 cmH(2)O or a maximal urethral closure pressure <20 cmH(2)O, consensus is lacking. As a result, studies evaluating ...
Hummel Scott L - - 2012
Recent studies suggest that oxidative stress and vascular dysfunction contribute to heart failure with preserved ejection fraction (HFPEF). In salt-sensitive HFPEF animal models, diets low in sodium and high in potassium, calcium, magnesium, and antioxidants attenuate oxidative stress and cardiovascular damage. We hypothesized that the sodium-restricted Dietary Approaches to Stop ...
Saint-Remy Annie - - 2012
ABSTRACT: BACKGROUND: In kidney transplant (Kt) recipients, hypertension is a major risk for cardiovascular complications but also for graft failure. Blood pressure (BP) control is therefore mandatory. Office BP (OBP) remains frequently used for clinical decisions, however home BP (HBP) have brought a significant improvement in the BP control. Sodium ...
Höglund K - - 2012
BACKGROUND: Correct interpretation of blood pressure (BP) and heart rate (HR) recordings is important in a clinical environment, but little is known about effects of stress on BP and HR responses of dogs to different clinical settings. OBJECTIVE: To investigate BP and HR responses in different clinical settings in dogs ...
Carroll Douglas D School of Sport and Exercise Sciences, University of Birmingham, Birmingham, England, - - 2012
Exaggerated cardiovascular reactions to acute psychological stress may be involved in the etiology of cardiovascular pathology. The present analysis examined the association between the magnitude of systolic and diastolic blood pressure reactions to stress and cardiovascular disease mortality. Participants were 431 (229 women) from the West of Scotland Twenty-07 Study, ...
Evrard Estérine - - 2012
Physiological and genetic responses of age 0+ Platichthys flesus were investigated in the eutrophicated and moderately contaminated Vilaine estuary, during a 6-month survey. The main objective of this study was to explore the biological responses of fishes during their juvenile period in an estuarine system in order to detect a ...
Kumar Bipin - - 2012
Understanding the stress relaxation behavior of the compression bandage could be very useful in determining the behavior of the interface pressure exerted by the bandage on a limb during the course of the compression treatment. There has been no comprehensive study in the literature to investigate the pressure profile (interface ...
Caciari T - - 2012
Cadmium (Cd) is a metal, which induces hypertension in animals. This may not be relevant to the human population because the number of studies is inconsistent. Our aim is to identify an association between levels of blood/urinary cadmium and blood pressure in a group of employees of the municipal police ...
Newman Aem - - 2012
The effects of chronic stressors on glucocorticoid levels are well described in laboratory rodents, but far less is known about the effects of chronic stressors on wild animals or on dehydroepiandrosterone (DHEA) levels. DHEA can be produced by the adrenal cortex and has prominent antiglucocorticoid properties. Here, we examined wild ...
Ejike Cecc - - 2012
Background: Little is known about the association between blood pressure and urinary electrolytes in young adult, nonurban-dwelling, sub-Saharan Africans. This study attempts to provide such data in a Nigerian population. Patients and Methods: Four hundred Nigerians (50% female) aged 19-40 years were studied. Their blood pressures (BPs), anthropometric variables, and ...
Bahrani Seyed Amir SA LaSIE, FRE-CNRS 3474, La Rochelle University, Avenue Michel Crépeau, 17042 La Rochelle, - - 2012
Standard maize starch (SMS) was hydrothermally treated by three processes; DV-HMT (Direct Vapor-Heat Moisture Treatment), RP-HMT (Reduced-Pressurized Heat Moisture Treatment) and DIC (in French: Détente Instantanée Contrôlée, instantaneous controlled pressure drop). Impact of processes were studied in order to determine the role of added steps of vacuum before and after ...
Perge Christophe - - 2012
We report measurements of the pressure profile in the outlet plane of a discharging silo. We observe that, whatever the preparation of the granular system, a dynamic Janssen effect is at play: the apparent mass of the grains (i.e., the part of their mass sustained by the base) is significantly ...
Mok Shaffer R S - - 2012
Normal pressure hydrocephalus (NPH) is composed of gait abnormalities, urinary incontinence and decline in mentation. It is uncommonly induced by syphilitic infection. A 76 year-old male present with gait disturbances, urinary incontinence, declining vision and cognition, with a known diagnosis of NPH. He underwent therapeutic lumbar puncture (LP), which demonstrated ...
Elixmann Inga Margrit - - 2012
Several models are available to simulate raised intracranial pressure (ICP) in hydrocephalus. However, the hydrodynamic effect of an implanted shunt has seldom been examined. In this study, the simple model of Ursino and Lodi [14]is extended to include (1) the effect of a typical ball-in-cone valve, (2) the effect of ...
Yoto Ai - - 2012
L-theanine, an amino acid contained in green tea leaves, is known to block the binding of L-glutamic acid to glutamate receptors in the brain, and has been considered to cause anti-stress effects by inhibiting cortical neuron excitation. Both L-theanine and caffeine, which green tea contains, have been highlighted for their ...
van Dijk Aimée E - - 2012
Prenatal maternal stress could have permanent effects on the offspring's tissue structure and function, which may predispose to cardiovascular diseases. We investigated whether maternal psychosocial stress is a prenatal factor affecting the blood pressure (BP) of offspring. In the Amsterdam Born Children and their Development (ABCD) study, around gestational week ...
Ichinose Masashi - - 2012
The mechanisms by which blood pressure is maintained against the orthostatic stress caused by gravity's effect on the fluid distribution within the body are important issues in physiology, especially in humans who usually adopt an upright posture. Peripheral vasoconstriction and increased heart rate (HR) are major cardiovascular adjustments to orthostatic ...
Weir Matthew R MR University of Maryland School of Medicine, Baltimore, MD, USA. - - 2012
While higher blood pressure is known to increase proteinuria, whether increased dietary sodium as estimated from 24-hour urinary excretion correlates with increased proteinuria in patients with chronic kidney disease (CKD) is not well studied. We measured 24-hour urinary sodium, potassium and protein excretion in 3,680 participants in the Chronic Renal ...
Schatschneider Bohdan - - 2011
The isostatic pressure response of crystalline indole up to 25 GPa was investigated through static geometry optimization using Tkatchenko-Scheffler dispersion-corrected density functional theory method. Different symmetries were identified in the structural evolution with increased pressure, but no motif transition was observed, owing to the stability of the herringbone (HB) motif ...
Patronik Nicholas A NA The Robotics Institute, Carnegie Mellon University, Pittsburgh, PA 15213, - - 2012
HeartLander is a miniature mobile robot designed to navigate over the epicardium of the beating heart for minimally invasive therapy. This paper presents a technique to decrease slippage and improve locomotion efficiency by synchronizing the locomotion with the intrapericardial pressure variations of the respiration and heartbeat cycles. Respiratory and heartbeat ...
Schreiber Sebastian - - 2011
We present a Metropolis Monte Carlo simulation algorithm for the Tpπ-ensemble, where T is the temperature, p is the overall external pressure, and π is the osmotic pressure across the membrane. The algorithm, which can be applied to small molecules or sorption of small molecules in polymer networks, is tested ...
Lin Z Z Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611-2951, USA. - - 2012
The distal contractile integral (DCI) is an index of contractile vigor in high-resolution esophageal pressure topography (EPT) calculated as the product of amplitude, duration, and span of the distal esophageal contraction. The aim of this study was to develop an automated algorithm calculating DCI. The DCI was calculated conventionally using ...
Cannesson Maxime - - 2011
OBJECTIVE:: To investigate the ability of a new stroke volume variation algorithm to predict fluid responsiveness during general anesthesia and mechanical ventilation in animals with multiple extrasystoles. DESIGN:: Prospective laboratory animal experiment. SETTING:: Investigational laboratory. SUBJECTS:: Eight instrumented pigs. INTERVENTIONS:: Eight anesthetized and mechanically ventilated pigs were monitored with an ...
Thiele Robert H - - 2011
Qualitative arterial waveform analysis has been in existence for millennia; quantitative arterial waveform analysis techniques, which can be traced back to Euler's work in the 18th century, have not been widely used by anesthesiologists and other clinicians. This is likely attributable, in part, to the widespread use of the sphygmomanometer, ...
Yang Li - - 2011
We present an algorithm to identify the onset of intracranial pressure (ICP) pulses. The algorithm creates a waveform descriptor to extract the feature of each local minimum of the waveform and then identifies the onset by comparing the feature with a customized template. The waveform descriptor is derived by transforming ...
Klingenberg C - - 2011
A recent systematic review and meta-analysis shows that volume-targeted ventilation (VTV) compared with pressure-limited ventilation (PLV) reduce death and bronchopulmonary dysplasia, pneumothorax, hypocarbia and severe cranial ultrasound abnormalities. In this paper, we present published research and our experience with volume guarantee (VG) ventilation, a VTV mode available on the Dräger ...
Norton Linda - - 2011
PURPOSE:: To enhance the learner's competence with knowledge of forces that affect skin breakdown and available bed surface support selections to help reduce the incidence of pressure ulcers (PrUs). TARGET AUDIENCE:: This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES:: ...
Mun Ji Hun - - 2011
The vienna-type differential mobility analyzer (DMA) was developed for the measurement of wide-range nm-sized particles under low-pressure conditions (2.9-8 kPa) with the faraday cup electrometer (FCE). The length, inner and outer diameter of DMA are calculated as a function of flow rate, applied voltage, pressure, and particle diameter to avoide ...
Luiz Alexandre Bastos - - 2011
ABSTRACT: Background Hypertension is a clinical condition that manifests target-organ damage (TOD) with symptoms. This study investigates the association between Zangfu patterns and symptomatic manifestations of TOD. Methods Datasets with manifestations of Zangfu patterns (Liver-fire blazing upwards; Kidney-yin deficiency and Liver-yang rising; obstruction of phlegm and dampness of Heart/Liver/Gallbladder; qi ...
White Kellee - - 2011
BackgroundResearch examining the association of residence in racially segregated neighborhoods with physical and mental health outcomes among blacks is mixed. Research elucidating the relationship between segregation and hypertension has been limited. This study examines the association between segregation and hypertension among US- and foreign-born blacks in New York City (NYC).MethodsIndividual-level ...
Yousefi R R Quality of Life Technology Laboratory The University of Texas at Dallas, Richardson, TX 75080, USA. - - 2011
Pressure ulcer is an age-old problem imposing a huge cost to our health care system. Detecting and keeping record of the patient's posture on bed, help care givers reposition patient more efficiently and reduce the risk of developing pressure ulcer. In this paper, a commercial pressure mapping system is used ...
Jiang Yinlai Y School of Systems Engineering, Kochi University of Technology, Kami, Kochi, Japan. - - 2011
We have been developing an omnidirectional walker (ODW) for walking support. In walking support, it is necessary control the ODW following the user's direction and velocity intentions. In this paper, a novel interface is proposed to recognize the user's intentions according to the forearm pressures. The forearm pressures exerted to ...
Meunier Julie - - 2011
The aim of this study was to investigate residents' characteristics associated with their performance in detecting patients' distress (detection performance). Residents' detection performance was assessed in a clinical round. A mean detection performance score was calculated for each resident by comparing residents' rating of patients' distress (VAS) with patients' reported ...
Yuasa Fumio - - 2011
Background:  Clonidine is a potent sympatholytic drug with central neural effects. The aim of this study was to evaluate the effects of clonidine on arterial baroreflex sensitivity (BRS) and cardiopulmonary (CP) baroreflex control of muscle sympathetic nerve activity (MSNA) in patients with left ventricular (LV) dysfunction. Method:  Twenty patients were ...
Sakuma Takao - - 2010
The rostral ventrolateral medulla (RVLM) is an important center for regulation of sympathetic nerve activity. Several clinical studies have suggested an association between neurovascular contact (NVC) of RVLM and essential hypertension. Microvascular decompression (MVD) of RVLM decreases blood pressure (BP) in hypertensive patients with NVC of this region. Therefore, MVD ...
Subash P - - 2010
Establishment of non-invasive urinary biomarker for the early prediction of essential hypertension (EH) is important. We evaluated whether estimation of urinary DNA, serves as a marker to predict the extent of cellular oxidative stress in essential hypertension. A total of 180 South Indian subjects aged 30-65 were recruited for the ...
Dewandre P Y - - 2010
Sufentanil 5 microg and clonidine 75 microg produce a similar reduction in minimum local anaesthetic concentration of ropivacaine. The aim of the present study was to compare the side effects of two equianalgesic solutions by combining 0.2% ropivacaine with either sufentanil 5 microg or clonidine 75 microg for labour epidural ...
Ong H T - - 2010
A study of residents at the Silver Jubilee Home for the Aged was conducted to determine the prevalence, awareness and control of hypertension in this elderly community in Penang, Malaysia. Prevalence of hypertension was 36%, with 81% of patients being initially aware of this diagnosis. This relatively low hypertension prevalence ...
Kobayashi Shinya - - 2010
We compared the effects of the selective alpha(1A)-adrenoceptor antagonist silodosin and the selective alpha(1D)-adrenoceptor antagonist naftopidil on intraureteral pressure in anesthetized dogs and evaluated their uroselectivity. Using anesthesia the effects of silodosin and naftopidil were evaluated by the phenylephrine induced increase in intravesical ureteral pressure and on blood pressure. Each ...
Marashi Seyed Mojtaba - - 2009
The present study was conducted to compare the effect of clonidine and gabapentin premedication in modifying the hyperdynamic response following laryngoscopy and tracheal intubation. Seventy-five ASA I-II patients of both sexes (37 males (49.3%), 38 females (50.7%)) 18 to 45 years (mean 32.8 +/- 8.65 yr.) were randomly allocated into ...
Brusberg Mikael - - 2008
The alpha(2)-adrenoceptor agonist, clonidine, modulates colorectal sensorimotor functions in humans and, given intrathecally, has analgesic effects in the colorectal distension (CRD) model in rats. We tested the effects of systemic clonidine on the visceral pain-related viscerosomatic and autonomic cardiovascular responses to CRD and colonic compliance in rats using clinically relevant ...
Toader Emil - - 2008
BACKGROUND: Cardiac vagal activity is now considered as an important therapeutic target. However, there is a lack of direct data on how cardiac vagal motoneurons respond to parasympathomimetic agents. METHODS: Rats were anesthetized with urethane and mechanically ventilated. Single-unit activity was recorded in the nucleus ambiguus from cardiac vagal motoneurons, ...
Park-Holohan So-Jin SJ Hammersmith Imanet Ltd., GE HealthCare, Cyclotron Building, Hammersmith Hospital, Du Cane Road, London, - - 2008
An increase in human cardiac alpha(1)-adrenoceptor (alpha(1)-AR) density is associated with various diseases such as myocardial ischemia, congestive heart failure, hypertrophic cardiomyopathy and hypertension. Positron emission tomography (PET) with an appropriate radioligand offers the possibility of imaging receptor function in the normal and diseased heart. [(11)C]GB67, an analogue of prazosin, ...
Lyssand John S JS Department of Pharmacology, University of Washington, Seattle, Washington 98195, - - 2008
Hypertension is a cardiovascular disease associated with increased plasma catecholamines, overactivation of the sympathetic nervous system, and increased vascular tone and total peripheral resistance. A key regulator of sympathetic nervous system function is the alpha(1D)-adrenergic receptor (AR), which belongs to the adrenergic family of G-protein-coupled receptors (GPCRs). Endogenous catecholamines norepinephrine ...
Dória Renata G S - - 2008
OBJECTIVE: To evaluate the cardiorespiratory and behavioural effects of epidural xylazine (XYL) or clonidine (CLO) in horses. STUDY DESIGN: Blinded, randomized experimental study. ANIMALS: Twelve healthy Arabian yearling horses weighing 117-204 kg were randomly allocated into two groups: XYL (n = 6) and CLO (n = 6). METHODS: An epidural ...
Yilmaz Mustafa S - - 2008
The mechanism responsible for the initiation of endotoxic hypotension is not fully understood, although it is often attributed to a direct effect of LPS and other vasoactive mediators on the vasculature. Alternatively, recent evidence raises the possibility that endotoxic hypotension may be initiated through a central mechanism. Previous studies have ...
Mann Samuel J - - 2008
Paroxysmal hypertension always engenders a search for a catecholamine-secreting pheochromocytoma. Yet 98% of people with paroxysmal hypertension do not have this tumor. The cause and management of paroxysmal hypertension remain a mystery, and the subject of remarkably few papers. This review presents an approach to understanding and successfully treating this ...
Erkonen Gwen - - 2008
INTRODUCTION: Dexmedetomidine is a centrally acting alpha(2)-adrenergic agonist which is currently FDA-approved for the short-term (less than 24 h) sedation of adults during mechanical ventilation. DISCUSSION: Given its beneficial physiologic properties, there has been increasing use of this agent in the pediatric population. As with any agent used for sedation ...
Cividjian A - - 2008
BACKGROUND: In the post-operative setting, pressure lability is increased in hypertensive patients. alpha-2 agonists were shown qualitatively to reduce this lability qualitatively. Here, upon immobilization combined with emergence from anesthesia in rats and clonidine administration, pressure lability was quantitatively assessed and related to baroreflex sensitivity. METHODS: After local anesthesia of ...
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