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Mulkerrin E C - - 1997
We studied blood pressure and natriuretic responses to acute salt loading, and the effect of non-steroidal anti-inflammatory agents on these responses, in five healthy normotensive women aged 65 to 71 years. Five women aged 25 to 31 years acted as controls. Intravenous saline loading, with and without prior ingestion of ...
Yi Jong-Yoon - - 1997
Cardiovascular disease is still the most common cause of morbidity and mortality in the elderly and hypertension is a significant risk factor for CVD such as stroke, myocardial infarction, and chronic renal disease. Fortunately, hypertension is readily treatable. A clear benefit from treating elevated blood pressure has been demonstrated by ...
Nwachuku C E - - 1997
The highlights of each generation of hypertension trials have been varied, but interrelated. The initial hypertension trials focused on middle-aged hypertensive individuals and later on the elderly, with emphasis on diastolic blood pressure and subsequently on systolic blood pressure. Past generations of trials elucidated whether and whom to treat. The ...
Pirodda A - - 1997
In the absence of a satisfactory interpretation, sudden sensorineural hearing loss is often attributed either to infective phenomena or to organic-type circulatory defects. This latter pathogenesis inevitably comes to mind in elderly patients or in the presence of signs of circulatory dysfunction. Nevertheless, the not-infrequent observation of sudden hearing loss ...
Gouyon J B - - 1997
Eight preterm infants were given intravenous nicardipine, a calcium channel blocker, to treat systemic hypertension (renal artery thrombosis (n = 3); dexamethasone for management of bronchopulmonary dysplasia (n = 2); unexplained (n = 3). Nicardipine doses ranged from 0.5 to 2.0 micrograms/kg/min and were given for three to 36 days ...
Wajngarten Mauricio - - 1997
Hypertension is accepted as a risk factor for cardiovascular disease in the elderly population. Data supporting the benefit of treating hypertension in the elderly is extensive but it continues to be poorly recognized and treated in the general population. The correct diagnosis is the initial step for avoiding common side ...
Tracy R E - - 1997
In essential hypertension, specific vasculopathies distinguish the kidney of nephrosclerosis. The severity of renovasculopathy can be measured histologically at autopsy. A previously determined equation uses the measurements to calculate mean blood pressure levels. That equation did not encompass elderly subjects with minimal vasculopathy, because they were deficient in the previous ...
Burris James F. - - 1997
The high incidence of hypertension among the elderly makes a once-daily multimechanism antihypertensive an advantageous agent for the control of hypertension. Because of its safety and efficacy in earlier studies, a low-dose multimechanism à -blocker/diuretic, bisoprolol fumarate 2.5, 5, or 10 mg combined with HCTZ 6.25 mg, was evaluated in ...
Del Torre - - 1996
BACKGROUND: It has been claimed that isolated systolic hypertension (ISH) in the elderly is not a sustained condition but a short-lasting increase in office systolic blood pressure magnified by arterial stiffness. DESIGN: Office and ambulatory blood pressures werecompared at baseline and after 3 months of observation of young and elderly ...
Paciaroni E - - 1996
Arterial hypertension in the elderly is an argument of growing interest and relevance in our society for many reasons, the main ones being: (i) Progressive aging of the population with a particularly high number of very old subjects. (ii) The high prevalence of arterial hypertension found mainly as an isolated ...
Hansson L - - 1996
TREATMENT OF ELDERLY HYPERTENSIVES: Treatment of hypertension in the elderly is nowadays an accepted and highly effective medical intervention following the positive reports on the benefits of lowering elevated arterial pressure in elderly patients. Most of the intervention studies an antihypertensive treatment in elderly patients have used diuretics or beta-blockers ...
Marlowe D B - - 1996
This paper reports preliminary data derived from a standardized interview scoring procedure for detecting and characterizing coercive and noncoercive pressures to enter substance abuse treatment. Coercive and noncoercive pressures stemming from multiple psychosocial domains are operationalized through recourse to established behavioral principles. Inter-rater reliability for the scoring procedure was exceptional ...
Massalha R - - 1996
Although chronic arterial hypertension is the leading cause of intracranial hemorrhage, an abrupt rise in systemic arterial pressure in normotensive people may sometimes induce a hemorrhagic stroke. Dental treatment is rarely associated with such an event. We report here on two middle-aged women, apparently healthy, who suffered from a fatal ...
Lindholm L H - - 1996
OBJECTIVE: The Swedish Trial in Old Patients with Hypertension-2 (STOP-Hypertension-2) was designed by a project group of the Swedish Hypertension Society to test whether the "newer" treatment alternatives (ACE inhibitors and calcium antagonists) are as good as, better or less good than, the "older" ones (beta-blockers and diuretics) in terms ...
Kohara K K 2nd Department of Internal Medicine, Ehime University School of Medicine, - - 1996
The effect of administration of an angiotensin-converting enzyme inhibitor, alacepril, on 24-hour blood pressure in the elderly hypertensive patients was investigated. Thirteen elderly hypertensive patients (mean age 71 +/- 5; 6 male and 7 female) participated in the present study. After 2 weeks of control period alacepril was administered 25-50 ...
Kondo K - - 1996
A 28-year-old woman with inoperable gastric carcinoma was given continuous infusion of 5-fluorouracil (5-FU) and low-dose cisplatin (CDDP) for 4 weeks while receiving intravenous hyperalimentation (IVH). Eleven days after her last treatment, she developed acute diplopia, deafness and gait ataxia, followed by severe confusion. She became markedly acidotic and hypotensive ...
Hall W D - - 1996
This article addresses management of hypertension in the elderly, with a specific focus on systolic hypertension wherever data are available. Validity of office and home blood pressure readings is discussed with attention to a variety of measurement artifacts in the elderly. The efficacy of lifestyle modifications is summarized. The 1994 ...
Smets K - - 1996
To assess the role of dexamethasone treatment as a cause of systemic hypertension and associated complications, blood pressure was registered prospectively before, during and after a 4-week dexamethasone course in 22 neonates with chronic lung disease. In all patients systolic blood pressure rose significantly during treatment (median rise 34 mm ...
Brand H S - - 1996
Changes in mean heart rate and mean systolic and diastolic blood pressure are induced in both the patient's anticipation of scheduled treatment and the actual dental treatment itself. Significant changes have been observed before application of a local anesthetic, during restorative treatment, during extractions, and when epinephrine-impregnated retraction cords were ...
Collins K J - - 1996
1. The effects of convective facial cooling by cold air on arterial blood pressure, heart rate and finger blood flow and on the reflex interactions between facial cooling and respiratory and orthostatic cardiac reflexes have been examined in 28 young adults (20-39 years) and 17 elderly (66-78 years) volunteer subjects. ...
Trenkwalder P - - 1996
The aim of the study was to compare the antihypertensive efficacy of either felodipine or the diuretic combination hydrochlorothiazide/triamterene in a group (n = 65) of elderly (> or = 70 years) hypertensives (office blood pressure > or = 160/95 mmHg) with special regard to ambulatory blood pressure monitoring, hypertensive ...
Lindholm L H - - 1996
Drug treatment with beta-blockers and diuretics in hypertensive men and women aged 70 and above confers highly significant and clinically relevant reductions in cardiovascular (especially stroke) morbidity and mortality. This satisfactory effect is not impaired by a low tolerability of the drugs used. Furthermore, treatment of elderly hypertensives with beta-receptor ...
Spahn D R - - 1996
Hemodilution tolerance is not well defined in elderly patients. In 20 patients older than 65 yr and free from known cardiovascular disease, hemodynamic variables, ST segment deviation, and O2 consumption were determined prior to and after 6 and after 12 mL/kg isovolemic exchange of blood for 6% hydroxyethyl starch. The ...
Wren B - - 1996
Menorest is an adhesive matrix patch containing 17 beta-estradiol at various doses. Menorest 50 micrograms/day has been compared with oral equine estrogens (Premarin 0.625 mg/day) and with a reservoir patch, Estraderm at 50 micrograms/day. Menorest was as effective as either of the two comparison treatments in controlling vasovagal and urinogenital ...
Teo G S - - 1996
A cross-sectional study was carried out to determine the prevalence of hypertension in the Chinese elderly and to examine its relationship with various behavioural and nutritional risk factors. This study involved 243 Chinese aged 55 years and older in 2 randomly selected Chinese Villages in Seberang Prai Tengah, Penang. The ...
Bonacci E - - 1996
Hypertension represents one of the most important atherosclerotic risk factors, since it causes vascular damage both to macro- and microcirculation. Capillaroscopy is very useful to examine "in vivo" the small vessels of nail-fold and conjunctival layer of the bulb which are the most suitable areas for a morphological study of ...
Trenkwalder P - - 1996
Application and feasibility of automated ambulatory blood pressure measurement (ABPM) in the elderly are comparable to younger age groups. Major side-effects are sleep disturbances and pain during cuff-inflation. The main indications for ABPM are diagnosis and control of treatment in hypertensive patients. Further indications are the diagnosis of syncope or ...
Kario K - - 1996
To study the relation between diurnal blood pressure variations and silent cerebrovascular damage, we performed both 24-hour ambulatory blood pressure monitoring and brain magnetic resonance imaging in 131 elderly asymptomatic hypertensive patients. Silent cerebrovascular damage was identified by the magnetic resonance imaging findings of lacunae (low intensity in T1-weighted images ...
Salvioli G - - 1996
Food intake induces splanchnic vasodilation lasting for at least one hour, which can precipitate in postprandial hypotension, if systolic arterial blood pressure falls by more than 20 mmHg. Postprandial hypotension has a high prevalence in the elderly, above all in subjects receiving hypotensive drugs or in those with disorders of ...
Andros E - - 1996
OBJECTIVE: The effect of age on the pharmacokinetics and pharmacodynamics of prazosin (alpha 1 adrenoceptor blocker) was studied in 20 healthy volunteers. PATIENTS: Ten elderly (61-81 y) and ten young (23-28 y) subjects were studied. All subjects received 1 mg of prazosin orally in a fasting state. Serial blood samples ...
Ross R D - - 1996
BACKGROUND: Idiopathic polypoidal choroidal vasculopathy (IPCV), the posterior uveal bleeding syndrome, and multiple recurrent serosanguineous pigment epithelial detachments in black women are a heterogeneous group of related entities seen in elderly hypertensive females. Similar associations are known for retinal arterial macroaneurysm (RAM). METHODS: This report documents the clinical, fluorescein, and ...
Gofin J - - 1995
Change in blood pressure levels over time was investigated in Jerusalem, in two cross-sectional surveys in 1970 and in 1986 among residents of a neighbourhood aged 50 years and more. The study population comprised 1397 individuals in 1970 and 1858 in the 1986. Age-adjusted mean systolic and diastolic blood pressure ...
Fotherby M D - - 1995
OBJECTIVE: To compare clinic and 24-h blood pressure levels and profiles in young elderly (aged 65-79 years) and old elderly (aged > or = 80 years) subjects. SUBJECTS AND METHODS: A cross-sectional observational study was conducted on 108 ambulant subjects (51 males) aged 65-95 years with no known history of ...
Zanchetti A - - 1995
To assess the benefits of the calcium antagonist lacidipine on the prevention of cardiovascular events and the prevention of organ damage in two long-term clinical trials. SYSTOLIC HYPERTENSION IN THE ELDERLY LONG-TERM LACIDIPINE (SHELL) TRIAL: In the SHELL trial, the efficacy of lacidipine-based treatment is to be compared with that ...
Bhattacharya R - - 1995
Toxicological evaluation of two recently reported treatment protocols for cyanide--SN (sodium nitrite) + DMAP (4-dimethylaminophenol) and SN + HA (hydroxylamine)--was carried out in male rats. Both treatments produced transient hyperammonaemia and decreased mean arterial pressure. Heart rate decreased and respiratory rate increased, but these changes reached the level of significance ...
Israili Z H - - 1995
High blood pressure (BP) in the elderly must not be ignored as a normal consequence of aging. The criteria for the diagnosis of hypertension and the necessity to treat it are the same in elderly and younger patients. The aim of treatment of elderly hypertensive patients is to decrease BP ...
Glynn R J - - 1995
BACKGROUND: During the 1980s data became available from randomized trials concerning the clear benefits of treating hypertension in the elderly. In three large communities, we examined the impact of these findings on rates of treatment, use of specific antihypertensive drugs, and rates of elevated blood pressure as well as distributions ...
Catipović-Veselica K - - 1995
Hypertension prevalence, awareness of high blood pressure, its treatment and control were estimated in 1100 workers, between the ages 35 and 59. Hypertension was defined as blood pressure > or = 160/95 mm Hg. The incidence of hypertensive heart disease was also investigated. All hypertensive persons were taken M-mode and ...
Fukuda H - - 1995
BACKGROUND AND PURPOSE: Several reports have stated that the periventricular abnormalities found on T2-weighted MRI or CT are associated with age and hypertension. However, there have been no reports on the effect of hypertension treatment on white matter abnormalities. We studied the association between cardiovascular risk factors and periventricular hyperintensities ...
Newman M F - - 1995
Central nervous system dysfunction is a common consequence of otherwise uncomplicated cardiac surgery. Many mechanisms have been postulated for the cognitive dysfunction that is part of these neurologic sequelae. The purpose of our investigation was to evaluate the effects of mean arterial pressure (MAP) during cardiopulmonary bypass (CPB) and the ...
Steinbrecher H A - - 1995
OBJECTIVE: To determine the incidence and outcome of hypertension associated with Wilms' tumour and to reduce peri-operative morbidity by appropriate treatment. PATIENTS AND METHODS: The medical and nursing case-notes of 17 consecutive patients with Wilms' tumour treated over a 5.5 year period (1989-1994) were analysed retrospectively. RESULTS: Ten of 17 ...
Kelsey M C - - 1995
Prior studies have shown that in younger depressives undergoing ECT whose seizure durations declined despite maximum settings on three different ECT devices, pretreatment with caffeine lengthened seizures and resulted in clinical improvement. Caffeine (half life, 140-270 minutes) was well tolerated even in patients with pre-existing cardiovascular disease. The purpose of ...
Staley E C - - 1995
A 7-mo-old female Doberman Pinscher undergoing antibiotic treatment for tonsillitis was presented in near collapse with markedly low blood pressure, tachycardia, dilatation of pupils (non-responsive to light), and gastrointestinal distress. Since the owner could provide no history of significant toxin exposure, general supportive and non-specific toxicologic treatment protocols were initiated. ...
Jansen R W - - 1995
BACKGROUND: Syncope in older patients may be caused by a variety of disorders, including hypotension, but frequently remains unexplained. Postprandial hypotension is a common disorder of blood pressure regulation in the elderly. OBJECTIVE: To determine the pathogenic mechanisms and potential role of postprandial hypotension in elderly patients with otherwise unexplained ...
Handa S P - - 1995
The present study evaluated the relationship of plasma norepinephrine (NE) and aortic distensibility (AOD) in a group of elderly patients with isolated systolic hypertension. Aortic distensibility was calculated as AOD = 2 x (delta aortic diameter)/diastolic aortic diameter) x (delta aortic pressure). Results indicate that the aortic diameters were significantly ...
Antonicelli R - - 1995
Arterial hypertension is the most common cardiovascular risk factor in the elderly. Its clinical control emphasises the problem of the systems used for monitoring: clinical measurement by the physician, home self-monitoring, ambulatory monitoring, etc. In particular, in the elderly population, the self-monitoring of blood pressure can present further problems associated ...
Waldo M J - - 1995
1. The findings of this study contradicted those of previous studies in the areas of respiratory rates, conditioning, and the effect of exercise on diastolic blood pressure. 2. This study indicates that the heart's requirement for oxygen at a given MET load (a unit of energy cost-related to workload) is ...
Lucksted A - - 1995
OBJECTIVE: Mental health consumers with serious mental illness were surveyed to obtain information about their experiences with and attitudes toward forced psychiatric treatment. METHODS: A 61-item survey questionnaire developed by the authors was administered by consumer volunteers to 105 persons with serious mental illness who were attending seven rehabilitation centers ...
Mancia G - - 1995
Several lines of experimental and clinical evidence collected over the past ten years suggest that the aging process is characterized not only by profound structural cardiovascular alterations, but also by marked functional changes in the reflex mechanisms involved in the homeostatic control of the circulation. This paper will examine how ...
Strandgaard S - - 1995
Hypertension causes marked adaptive changes in the cerebral circulation. The excess risk of stroke associated with hypertension is eliminated in controlled trials of antihypertensive treatment. Such treatment may even prevent transient ischaemic attacks in the elderly. In rare cases, overzealous antihypertensive treatment may cause cerebral ischaemia, especially in the initial ...
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