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Acelajado Maria Czarina - - 2009
Hypertension is an important risk factor for cardiovascular morbidity and mortality, particularly in the elderly. Blood pressure elevation in the elderly is due to structural and functional changes that occur with aging. Treatment of hypertension reduces the risk of stroke, heart failure, myocardial infarction, all-cause mortality, cognitive impairment, and dementia ...
Gao Sujuan - - 2009
To examine the association between hypertension and cognitive decline in older adults. Prospective observational study. Four rural counties in China. Two thousand rural Chinese aged 65 and older (median age 70, range 65-92) participated in a baseline evaluation. A follow-up evaluation of 1,737 subjects was conducted 2.5 years after baseline. ...
Casiglia Edoardo - - 2009
High systolic blood pressure represents a challenge for the modern world. Epidemiologists are in the best position to appreciate the importance of systolic hypertension and its cardiovascular consequences. Although the label of hypertension seems to have lower importance in the elderly, and above all in the very old, than in ...
Yao Hiroshi - - 2009
Apathy is defined as a syndrome of primary loss of motivation not attributable to emotional distress, intellectual impairment or consciousness disturbance. The aim of our study was to investigate the effects of vascular risk factors and silent ischemic brain lesions on apathetic behavior of community-dwelling elderly subjects. Brain MRI and ...
Ferreira-Filho Sebastião R - - 2009
Aging is associated with changes in cardiovascular structure and function, which predisposes elderly people to reduced blood pressure levels after meals. The authors studied cardiac systolic function in elderly hypertensive patients after eating meals with different contents of lipids, proteins, and carbohydrates. Ten elderly male hypertensive patients were studied (mean ...
MANCIA, GIUSEPPE (7298)
In 22 elderly normotensive and 22 elderly untreated essential hypertensive subjects, we measured left ventricular mass, diastolic compliance, and carotid artery wall thickness and stiffness by ultrasonographic techniques. The results show that in the elderly, the presence of high blood pressure enhances the cardiovascular functional and structural alterations.
Baur Barbara - - 2009
STUDY DESIGN: Pre-post, single-group. INTRODUCTION: Writer's cramp (WC) is a focal dystonia causing impairments in daily life. Behavioral treatment approaches have been shown to improve handwriting performance, though outcomes remain sub-optimal. PURPOSE OF THE STUDY: To examine the effects of the handwriting training and auditory grip force feedback in seven ...
Alpérovitch Annick - - 2009
BACKGROUND: Seasonal variations of blood pressure-related diseases have been described in several populations. However, few studies have examined the seasonal variations of blood pressure in the elderly, a segment of the population particularly exposed to vascular diseases. The association of blood pressure with season and outdoor temperature was examined in ...
Miyazaki Masumi - - 2009
PURPOSE: Tracheal extubation and emergence procedures induce abrupt changes in hemodynamics and humoral responses. We conducted a prospective randomized study to examine the effects of the short-acting beta-1 blocker, landiolol, on hemodynamics during emergence from anesthesia in elderly patients with and without hypertension. METHODS: Thirty-one hypertensive and 32 normotensive elderly ...
Heagerty Anthony M - - 2009
The appearance and progression of essential hypertension is associated with increasing age. Older patients also frequently have an abnormally elevated systolic blood pressure (SBP) [> or =140 mmHg] without an elevated diastolic blood pressure (DBP) [< or =90 mmHg], a phenomenon known as isolated systolic hypertension. Thus, management of hypertension ...
- - 2008
The benefits of lowering a systolic blood pressure below 140 mmHg in elderly hypertension remain controversial. This study is a prospective, randomized, open-label study with blinded assessment of endpoints to compare the 2-year effect of strict treatment to maintain systolic blood pressure below 140 mmHg with that of mild treatment ...
Jennings J Richard - - 2008
Hypertension appears to alter brain morphology, as well as the cerebrovascular support for information processing. Because these effects might reflect progressive effects of essential hypertension on the brain, we asked whether structural and functional brain indices would predict the success of pharmacological treatment of hypertension among 45 previously unmedicated individuals. ...
Maule S - - 2008
Low blood pressure has been found to be associated with cognitive decline and dementia in cross-sectional studies. Two mechanisms have been proposed to interpret this association: blood pressure levels decrease during the course of the dementia process, and low blood pressure induces or accelerates cognitive decline by lowering cerebral blood ...
Joyeux V - - 2008
PURPOSE: In a stable patient population we evaluated on-line postdilution hemodiafiltration (HDF) on the incremental improvement in blood purification versus high-flux HD, using the same dialyzer and blood flow rate. For HDF we used a new way of controlling HDF treatments based on the concept of constant pressure control where ...
Umeki Youko - - 2008
Dried-bonito broth (DBB, katsuo-bushi dashi) is commonly used in Japanese cuisine, and is also used as a traditional remedy for recovery from fatigue and improvement of blood circulation. To clarify the effect of DBB on blood pressure, oxidative stress and emotional states, a randomized crossover human trial was performed. Twenty-seven ...
Amor Bouthaina Ben - - 2008
The study of the oligosaccharides extracted from Tephrosia purpurea seeds was undertaken using the instant controlled pressure drop (DIC) as a pre-treatment prior to conventional solvent extraction. This DIC procedure provided structural modification in terms of expansion, higher porosity and improvement of specific surface area; diffusion of solvent inside such ...
Jian Zai-jin - - 2008
BACKGROUND: Postprandial hypotension (PPH) occurs frequently in elderly people and may lead to syncope, falls, dizziness, weakness, angina pectoris, and stroke. Some studies suggest that the magnitude of the postprandial fall in blood pressure (BP) is influenced by the rate at which glucose enters the small intestine. We hypothesized that ...
Leibovitch Eric R - - 2008
Clinical studies continue to modify our approach to the older hypertensive patient. The pathophysiology of hypertension is now better understood from data derived from ambulatory blood pressure monitoring, the assessment of central arterial pressure and of vascular stiffness. This is altering both the ways we assess, monitor, and treat our ...
Haas Nikolaus A - - 2008
OBJECTIVE: Effects of timing of inception of amiodarone antiarrhythmic treatment after corrective surgery for congenital heart defects are not yet well defined. METHODS: In a 10-year prospective observational study, 71 of 2651 patients (2885 procedures, 2106 bypass procedures) received amiodarone for newly detected postoperative atrial (n = 70) or ventricular ...
Epstein Benjamin J - - 2008
OBJECTIVE: To summarize the role of the endothelin system (ETS) in cardiovascular disease (CVD) and evaluate the potential usefulness of darusentan, a selective endothelin type A (ET(A)) receptor antagonist, in the treatment of hypertension and chronic heart failure (CHF). DATA SOURCES: A literature search was conducted in MEDLINE (1966-February 2008), ...
Kim Dae-Hyun - - 2008
OBJECTIVE: Increased arterial stiffness is an independent predictor of cardiovascular diseases in hypertensive patients. Hypertension and aging can cause similar damage to small vessel walls. The objective of this study was to determine relationship between arterial stiffness measured by brachial-ankle pulse wave velocity (baPWV) and the risk of cerebral small ...
Chemla Denis - - 2008
1. Increased aortic stiffness predisposes to myocardial ischaemia by increasing the systolic tension-time index and by decreasing aortic pressure throughout diastole. The tonometric subendocardial viability ratio (SEVR) is a non-invasive estimate of myocardial perfusion relative to cardiac workload. The hypothesis that SEVR is impaired in elderly hypertensives with high aortic ...
Kim Kwang-Il - - 2008
With the progression of the aging population, common diseases of the elderly have become the center of attention in most developed countries. Hypertension is one of the most common morbid conditions in the elderly and has a great impact on their health status because it is the main risk factor ...
Duprez Daniel A - - 2008
Systolic hypertension is a major public health issue in the elderly and is often under-recognized and under-treated. The concept that systolic blood pressure increases with age should be considered a pathophysiologic concept. Aging of the cardiovascular system is accompanied by endothelial dysfunction, activation of the renin-angiotensin system and, consequently, vascular ...
Kalambokis Georgios - - 2008
Cirrhosis associated with moderate and severe portopulmonary hypertension carries a poor prognosis. Optimal management has not yet been defined. Current treatment options, such as prostacyclin analogues, endothelin antagonists, and phosphodiesterase-5 inhibitors, are characterized by slow onset of action and various adverse effects, particularly in patients with advanced cirrhosis. Here, we ...
Sentveld Bas - - 2008
Dialysis hypotension occurs frequently and is associated with increased morbidity, mortality, and may influence quality of life. We investigated the influence of blood volume (BV)-controlled ultrafiltration on hemodynamic stability and quality of life in a prospective multiple crossover study. Nineteen patients were consecutively treated with standard hemodialysis (HD), BV-controlled ultrafiltration, ...
Lim Joon-Ho - - 2008
As transformed to aging society rapidly, the number of old persons who live alone is drastically increased. Because these old people may have disorder of bodily function, and be suffering from geriatric disease, needs of a health assistance system to make them healthier are strongly increased. In this paper, we ...
Sugaya Kimio - - 2008
AIMS: Nocturia is a common symptom in the elderly, and various contributing factors have been suggested. Therefore, in order to investigate which factors are strongly related to occurrence of nocturia, we performed a suite of examinations. METHODS: One hundred eighty volunteers were divided into three groups: a young adult control ...
Hosgor Izzet - - 2008
Impaired fibrinolysis is associated with thromboembolic complications in hypertensive patients. Cardiovascular morbidity/mortality rates have been reported high even after lowering the elevated blood pressure with antihypertensive drugs. We investigated the effects of clinically used dosages of cilazapril on the fibrinolytic system in hypertensive patients. The present study was performed among ...
McDonald Ken - - 2008
Diastolic heart failure (DHF) is now firmly established as a significant contributor to the heart failure syndrome. However, compared to the better studied systolic dysfunction heart failure relatively little is known about this form of the syndrome. Epidemiological data have demonstrated that it is particularly important in the elderly likely ...
Bal Miriam P - - 2008
Dexamethasone is clinically applied in preterm infants to treat or prevent chronic lung disease. However, concern has emerged about adverse side effects. The cardiovascular short-term side effects of neonatal dexamethasone treatment are well documented, but long-term consequences are unknown. Previous studies showed suppressed mitosis during dexamethasone treatment, leading to reduced ...
Shlyakhto Evgeny - - 2007
Given the ageing population, dementia is an ever-increasing health burden. A positive correlation between cognitive decline or dementia and blood pressure levels has been indicated. There is, however, conflicting evidence over the definitive link between the use of antihypertensives and the subsequent reduction of cognitive decline. The specific use of ...
Cherubini Antonio - - 2007
Alzheimer's disease is the most prevalent and common form of cognitive impairment, ie, dementia, in the elderly followed in second place by vascular dementia due to the microangiopathy associated with poorly-controlled hypertension. Besides blood pressure elevation, advancing age is the strongest risk factor for dementia. Deterioration of intellectual function and ...
Lees Robert S - - 2007
This review focuses on the role of lipid-lowering, blood pressure-lowering, antithrombotic drugs and diet and their place in the prevention and treatment of atherosclerosis in middle-aged and elderly men and woman. The major emphasis is on noninvasive assessment of the extent of atherosclerotic plaque and the importance of following plaque ...
Zanchetti Alberto - - 2007
BACKGROUND: A number of patients with chronic heart failure (CHF) have diastolic but not systolic dysfunction. This occurs particularly in the elderly and in hypertension, but the prevalence of diastolic dysfunction in elderly hypertensives without CHF has never been investigated systematically. METHODS AND RESULTS: The Assessment of PRevalence Observational Study ...
Mallion Jean-Michel - - 2007
The prevalence of isolated systolic hypertension (ISH) is high in the elderly, and the objective of this study was to compare the antihypertensive efficacy of olmesartan medoxomil with that of nitrendipine in elderly (65-74 years) and very elderly (>/= 75 years) male and female patients with ISH. Patients were randomized ...
Okeahialam B N - - 2007
Erectile dysfunction (ED) is associated with hypertension and its treatment. It is known to impair and quality of life and compliance to treatment. This study excluded diseases which co-exist with hypertension as well as impair erectile function in their own right. This was to see how much of this problem ...
Fasce Eduardo - - 2007
OBJECTIVES: To evaluate the changes experienced over 15 years in the prevalence, state of awareness, treatment and control of hypertension, in urban communities of the VIII Region of Chile. METHODOLOGY: In order to ensure an objective analysis in comparison of the indicators, the methodological design used in 1988 was replicated: ...
de Deco Camila Porto - - 2007
OBJECTIVE: To evaluate the heart rate, blood pressure, blood glucose and other important indicators of the general health of an elderly population of São José dos Campos, Brazil. MATERIALS AND METHODS: A cross-sectional study was conducted among 150 institutionalised and 150 community-dwelling individuals aged 60 years or more. The parameters ...
Ono Takahiro - - 2007
OBJECTIVE: To investigate the influence of maximal bite force, maximal tongue pressure, number of mastications and swallowing on the oro-pharyngeal residue in the elderly. BACKGROUND: Oro-pharyngeal residue in the elderly is an indication of dysphagia. Pharyngeal residue is especially critical as it may cause aspiration pneumonia, which is one of ...
Guillamón Eva - - 2008
BACKGROUND: Lupin seed flour has been reported as a causative agent of allergic reactions, especially in patients with allergy to peanut. Previous studies have demonstrated that autoclave treatment can considerably reduce the allergenicity of lupins. AIMS: The aim of this work was to evaluate the effect of instantaneous controlled pressure ...
Khosravani Nina - - 2007
Dry mouth produces a deterioration in oral health and impairs quality of life. There is a need for a novel approach to the pharmacological treatment of dry mouth. With a view to enhancing the cholinergic drive on minor salivary glands, whilst at the same time minimising adverse systemic effects, the ...
Belletti Nicoletta - - 2007
The combined effects of a mild heat treatment (55 degrees C) and the presence of three aroma compounds [citron essential oil, citral, and (E)-2-hexenal] on the spoilage of noncarbonated beverages inoculated with different amounts of a Saccharomyces cerevisiae strain were evaluated. The results, expressed as growth/no growth, were elaborated using ...
López-Torres Miguel - - 2008
For elderly people, the desirable situation of living independently means facing everyday tasks and risks alone [Monk et al., 2006. Towards a practical framework for managing the risks of selecting technology to support independent living. Appl. Ergon. 37, 599-606]. One such task is buying a mattress through the same channels ...
Chaturvedi S - - 2007
Two cross-sectional, population-based studies were conducted to assess the prevalence, awareness, treatment and control of hypertension, among people aged 20-59 years and those over 60 years in Delhi. Study 1 (20-59 years): in total,1213 subjects from 120 clusters spread across Delhi were studied. The prevalence of hypertension was 27.5%. Of ...
Sakakura Kenichi - - 2007
BACKGROUND: It is reported that blood pressure (BP) variability increases with aging, and cognitive dysfunction may be related to BP variability; however, there are no data showing that exaggerated BP variability is associated with cognitive dysfunction or quality of life (QOL) in the older elderly. We investigated the relationships and ...
Mueller Andreas - - 2007
CONTEXT: The most common treatment regimen in female-to-male transsexuals is administration of short-acting testosterone esters im every 2 wk. OBJECTIVE: Our objective was to report the effects of administering long-acting testosterone undecanoate every 3 months on hormonal and clinical changes, mortality, morbidity, and safety during the first year of treatment ...
Makiyama Kiyoshi - - 2007
OBJECTIVE: The goal was to test the hypothesis that the elderly have diminished laryngeal regulation capability, so we investigated phonatory function in the elderly and young using a sound pressure-loading test. STUDY DESIGN AND SETTING: In 36 healthy men (17 in their 20s, 19 in their 70s) and 45 healthy ...
Mohan V - - 2007
OBJECTIVE: To study the prevalence, awareness and control of hypertension in Chennai representing Urban South India. METHODS: The Chennai Urban Rural Epidemiology Study (CURES) is one of the largest epidemiological studies on diabetes carried out in India, where 26,001 individuals aged > or = 20 years were screened using systematic ...
Paran Esther - - 2007
While the health and longevity benefits of antihypertensive treatment have been established in past research, the cognitive consequences of blood pressure control in the elderly are still under debate. In this paper, the authors review the current evidence and the different ways in which cognition is measured. Since research on ...
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