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Fu Jicheng - - 2012
We propose to construct an intelligent system for clinical guidance on how to effectively use power wheelchair tilt and recline functions. The motivations fall into the following two aspects. (1) People with spinal cord injury (SCI) are vulnerable to pressure ulcers. SCI can lead to structural and functional changes below ...
Kobayashi Hirokazu - - 2012
We have synthesized and characterized homogeneous solid-solution alloy nanoparticles of Pd and Rh, which are immiscible with each other in the equilibrium bulk state at around room temperature. The Pd-Rh alloy nanoparticles can absorb hydrogen at ambient pressure and the hydrogen pressure of Pd-Rh alloys for hydrogen storage is dramatically ...
Benjamin Ari S - - 2012
Acoustic properties of the fluorinated copolymer Kel F-800 were determined with Brillouin spectroscopy up to pressures of 85 GPa at 300 K. This research addresses outstanding issues in high-pressure polymer behavior, as to date the acoustic properties and equation of state of any polymer have not been determined above 20 ...
Somkuti Judit - - 2012
Fish allergy is associated with IgE-mediated hypersensitivity reactions to parvalbumins, which are small calcium-binding muscle proteins and represent the major and sole allergens for 95% of fish-allergic patients. We performed Fourier transform infrared and tryptophan fluorescence spectroscopy to explore the p-T phase diagram of cod parvalbumin (Gad m 1) and ...
Yoon Paula W - - 2012
Cardiovascular disease (CVD) is the leading cause of preventable death in the United States, and approximately 1 million heart attacks and 700,000 strokes occur annually. Hypertension is a major risk factor for cardiovascular disease and stroke; the unadjusted prevalence of hypertension among U.S. adults aged ≥18 years is approximately 31% ...
Appel Lawrence J - - 2012
Elevated blood pressure is a highly prevalent condition that is etiologically related to coronary heart disease and stroke, two of the leading causes of morbidity and mortality throughout the world. Excess salt (sodium chloride) intake is a major determinant of elevated blood pressure. In this article, we discuss the scientific ...
Pietosa J - - 2012
The pressure dependence, up to 11.3 kbar, of basic parameters of the superconducting state, such as the critical temperature (T(c)), the lower and the upper critical fields, the coherence length, the penetration depth, and their anisotropy, was determined from magnetic measurements performed for two single-crystalline samples of FeTe(0.5)Se(0.5). We have found ...
Mahlik S - - 2012
Steady state and time resolved luminescence measurements of CaMoO(4) doped with Pr(3+) as a function of hydrostatic pressure in the 1-175 kbar range are presented. It has been observed that with increasing pressure the spectral features shift towards lower energies, the decay times of both (3)P(0) and (1)D(2) emitting levels become ...
Neetoo Hudaa - - 2012
In summer of 2008, the United States witnessed one of the largest multi-state salmonellosis outbreak linked to the consumption of Jalapeño and Serrano peppers tainted with Salmonella enterica serovar Saintpaul. The first objective of this study was to assess the application of high hydrostatic pressure (HHP) to decontaminate Jalapeño and ...
Silva Leilane Bagno Eleutério da - - 2012
BACKGROUND: Inadequate life habits are known to favor hypertension, and Adventists recommend healthy life habits. OBJECTIVE: To assess the prevalence of hypertension among Seventh-Day Adventists from the inner São Paulo state and São Paulo state capital. METHODS: This study assessed 264 Adventists (mean age, 41.17 ± 15.27 years; women, 59.8%) ...
Ilton Eugene S - - 2012
Reactions involving variably hydrated super critical CO2 (scCO2) and a Na saturated dioctahedral smectite (Na-STX-1) were examined by in situ high-pressure x-ray diffraction at 50°C and 90 bars; conditions that are relevant to long term geologic storage of CO2. Both hydration and dehydration reactions were rapid with appreciable reaction occurring ...
Thiyagarajan R - - 2012
We have investigated the effect of hydrostatic pressure as a function of temperature on the resistivity of a single crystal of the bilayer manganite (La(0.4)Pr(0.6))(1.2)Sr(1.8)Mn(2)O(7). Whereas a strong insulating behaviour is observed at all temperatures at ambient pressure, a clear transition into a metallic-like behaviour is induced when the sample ...
Santamaria Ruben - - 2012
We investigate the behavior of a model methane clathrate cage under high hydrostatic pressures. The methane clathrate cage consists of 20 water molecules forming 12 pentagonal faces, with a methane molecule positioned at the cage center. The clathrate compound is located inside a fullerene-type arrangement of 180 He atoms to ...
Eide Per Kristian - - 2012
Object Indices of cerebrovascular pressure reactivity (CPR) represent surrogate markers of cerebral autoregulation. Given that intracranial pressure (ICP) wave amplitude-guided management, as compared with static ICP-guided management, improves outcome following aneurysmal subarachnoid hemorrhage (SAH), indices of CPR derived from pressure wave amplitudes should be further explored. This study was undertaken ...
Bay T V - - 2012
We report a high-pressure single crystal study of the topological superconductor Cu_{x}Bi_{2}Se_{3}. Resistivity measurements under pressure show superconductivity is depressed smoothly. At the same time the metallic behavior is gradually lost. The upper-critical field data B_{c2}(T) under pressure collapse onto a universal curve. The absence of Pauli limiting and the ...
Hamlin Robert L - - 2012
dP/dt(max) is the maximal rate of rise of (usually) left ventricular pressure (LVP), but it is determined by myocardial contractility and the loading conditions on the ventricle, thus it is an imperfect and sometimes incorrect predictor of the inotropic state (myocardial contractility). The value of dP/dt(max) to represent contractility may ...
Puthenpurackal Narayanan Sunilkumar - - 2012
We studied conformational fluctuations of the transcription factor c-Myb R2 subdomain (52 residues with three Trp) at high pressure and low temperature (5°C) using two different spectroscopic methods, Trp fluorescence and (1)H NMR, on its chemically stable mutant C130I (pseudo-wild-type (WT(S))), which has a large internal cavity. As pressure was ...
Bogie Kath - - 2012
Pressure sores are a serious, and costly, complication for many patients with reduced mobility and sensation. Some populations, such as those with spinal cord injury (SCI), remain at high risk throughout their lifetime. Prevention is highly preferable and while the concept is readily definable, it is much more challenging to ...
Onders Raymond P - - 2012
Tetraplegia can lead to chronic respiratory failure. The need for tracheostomy mechanical ventilation significantly increases the cost of care, decreases the quality of life of the patient, and decreases life expectancy in spinal cord injury (SCI) because of pneumonias. Phrenic nerve stimulation was initially developed in the 1960s and diaphragm ...
Yamashita Tae - - 2012
A 37-year-old man with C4-5 spinal cord injury (SCI) presented with abnormally high blood pressure after vesicocutaneous catheter exchange and was treated with antihypertensive agents. Two weeks later, he developed headache and visual disturbance, and presented with fluctuating blood pressure. Multiple subcortical hemorrhages in the left occipital and right frontal ...
Vaidyanathan Subramanian - - 2012
A 29-year-old man developed paraplegia at T-10 level due to road traffic accident in 1972. Both kidneys were normal and showed good function on intravenous urography. Division of external urethral sphincter was performed in 1973. In 1974, cystogram showed retrograde filling of left renal tract, which was hydronephrotic. Left ureteric ...
DellaVigna Stefano - - 2012
Every year, 90% of Americans give money to charities. Is such generosity necessarily welfare enhancing for the giver? We present a theoretical framework that distinguishes two types of motivation: individuals like to give, for example, due to altruism or warm glow, and individuals would rather not give but dislike saying ...
Bauman William A - - 2012
Persons with spinal cord injury (SCI) have secondary medical consequences of paralysis and/or the consequences of extreme inactivity. The metabolic changes that result from reduced activity include insulin resistance with carbohydrate disorders and dyslipidemia. A higher prevalence of coronary artery calcification was found in persons with SCI than that in ...
Rabchevsky Alexander G - - 2012
We recently reported that the neuropathic pain medication, gabapentin (GBP; Neurontin), significantly attenuated both noxious colorectal distension (CRD)-induced autonomic dysreflexia (AD) and tail pinch-induced spasticity compared to saline-treated cohorts 2-3 weeks after complete high thoracic (T4) spinal cord injury (SCI). Here we employed long-term blood pressure telemetry to test, firstly, ...
Arik M - - 2011
The CERN Axion Solar Telescope (CAST) has extended its search for solar axions by using ^{3}He as a buffer gas. At T=1.8  K this allows for larger pressure settings and hence sensitivity to higher axion masses than our previous measurements with ^{4}He. With about 1 h of data taking at each ...
Pantcheva Mina B - - 2011
OBJECTIVE: The objective of this review is to evaluate the safety and efficacy of tafluprost, a fluoroprostaglandin receptor analog, for reduction of intraocular pressure in open angle glaucoma and ocular hypertension. METHODS: A search of published literature was performed on the PubMed database using the search term "tafluprost." The literature ...
Daily Josiah C - - 2011
Abstract The National Association of EMS Physicians (NAEMSP) believes that noninvasive positive pressure ventilation (NIPPV) is an important treatment modality for the prehospital management of acute dyspnea. This document serves as a resource to the NAEMSP position on prehospital NIPPV.
Chen Yun - - 2011
Primary objective: A volumetric blood surge (rapid physical movement/displacement of blood) is hypothesized to cause the non-impact, mild TBI and battlefield PTSD induced by a blast over-pressure wave. Research design: Systematic review of the literature. Methods and procedures: Articles relating to the fields of blast injury, brain injury and relevant ...
Kolipaka Arunark - - 2011
To compare magnetic resonance elastography (MRE) effective stiffness to end-diastolic pressure at different loading conditions to demonstrate a relationship between myocardial MRE effective stiffness and end-diastolic left ventricular (LV) pressure. MRE was performed on four pigs to measure the end-diastolic effective stiffness under different loading conditions. End-diastolic pressure was increased ...
Fellahi Jean-Luc - - 2011
PURPOSE: An increase in abdominal pressure induces an increase in left ventricular afterload under clinical conditions. We tested the hypothesis that positive end-expiratory pressure (PEEP) could reverse the hemodynamic consequences of abdominal hyperpression by opposing the increase in left ventricular afterload. MATERIALS AND METHODS: Eight healthy volunteers were investigated during ...
Støverud K-H - - 2011
Phase contrast MR in patients with the Chiari I malformation demonstrates abnormal CSF flow in the foramen magnum and upper cervical spinal canal, related to abnormal pressure gradients. The purpose of this study was to analyze the role of CSF pressure in the pathogenesis of syringomyelia, with computational models. The ...
Dumitrescu Ioana - - 2011
Here we report that pressure-driven flow alone (no external electrical energy) can be used to drive faradaic electrochemical reactions in microchannels with charged walls. Specifically, we show that solution flow can generate streaming potentials on the order of volts and that this is sufficient to carry out reactions on the ...
Stöwhas Anne-Christin - - 2011
Abstract BACKGROUND: Preliminary evidence supports an association between obstructive sleep apnea (OSA) and thoracic aortic dilatation. The mechanisms through which OSA may promote thoracic aortic dilatation are incompletely understood. Therefore, we studied the acute effects of simulated apnea and hypopnea on aortic diameter and blood pressure in humans. METHODS: In ...
Kenny Damien - - 2011
We report successful deployment of a fenestrated Helex Septal Occluder in a 46-year-old lady with a moderate-sized secundum atrial septal defect and elevated left-ventricular end diastolic pressure secondary to renovascular hypertension. Initial balloon occlusion of the defect lead to significant rise in left atrial pressure. Creation of a 4-mm fenestration ...
Cao Jian - - 2011
We examined the hypothesis that vascular and renal dysfunction caused by angiotensin II (Ang II) through increased levels of blood pressure, inflammatory cytokines, and oxidative stress in Sprague-Dawley rats can be prevented by lentiviral-mediated delivery of endothelial heme oxygenase (HO)-1. We targeted the vascular endothelium using a lentiviral construct expressing ...
Hanson Angela - - 2011
OBJECTIVE:: To test the hypothesis that tidal elimination of carbon dioxide and dynamic compliance guided lung recruitment and positive end-expiratory pressure titration in surfactant-depleted piglets result in improved aeration (repeated computed tomography scans) and reduced ventilation pressures compared to those of a control group with conventional end-tidal carbon dioxide targeted ...
van Beek Arenda Hea - - 2011
BACKGROUND AND PURPOSE: The breath hold maneuver is a convenient and frequently used method to assess cerebrovascular reactivity (CR). This study aimed to assess feasibility and reproducibility of this method in healthy older persons. METHODS: Twenty-five healthy volunteers, aged 75 (SD 4) years, performed 2 consecutive breath holds after careful ...
Tikellis Chris - - 2011
Angiotensin-converting enzyme 2 (ACE2) has recently emerged as a key regulator of the renin-angiotensin system in both health and disease. ACE2 deficiency is associated with elevated tissue and circulating levels of angiotensin II and reduced levels of angiotensin 1-7. Phenotypically, this results in a modest elevation in systolic blood pressure ...
Olafiranye Oladipupo - - 2011
To characterize primate arterial waveforms, we prospectively studied 38 bonnet macaques (Macaca radiata; 25 female, 13 ± 4 y). Brachial artery waveforms were recorded from these animals by applanation tonometry and were decomposed into harmonics by using Fourier analysis. The ratio of individual to total harmonic amplitude (H:T) was derived ...
Do Doan Hoa - - 2011
Aim: Noninvasive markers of right ventricular (RV) diastolic dysfunction are limited by their lack of reproducibility and accuracy. We tested the hypothesis that right atrial (RA) size measured by echocardiography was correlated to invasive parameters of RV diastolic filling. Methods and Results: We studied 31 consecutive adult patients with congenital ...
Sim Lee Nuang - - 2011
Understanding the foulant deposition mechanism during crossflow filtration is critical in developing indices to predict fouling propensity of feed water for reverse osmosis (RO). Factors affecting the performance on different fouling indices such as MFI-UF constant pressure, MFI-UF constant flux and newly proposed fouling index, CFS-MFI(UF) were investigated. Crossflow Sampler-Modified ...
Kujal Petr - - 2010
1. Hypertension plays a critical role in the progression of chronic kidney disease (CKD) to end-stage renal disease (ESRD), but it has also been postulated that antihypertensive drugs that block the renin-angiotensin system (RAS) show class-specific renoprotective actions beyond their blood pressure (BP)-lowering effects. 2. Because this notion has recently ...
Shoucri Rachad M - - 2010
The problem of heart failure with preserved ejection fraction (HFpEF) has recently received much attention. In this study we discuss some relations that connect ejection fraction EF to the parameters describing the end-systolic pressure-volume relation (ESPVR). It is shown that the study of the relation between EF and ESPVR can ...
Schmieder Roland E - - 2010
End organ damage in hypertension can be detected early, reflects accurately the hypertensive patient's overall cardiovascular risk, and should be prevented and treated with antihypertensive treatment. We selectively review the relevant literature since 1995, including the German and European guidelines for the diagnosis and treatment of arterial hypertension. Measurement of ...
Ehlers Pauliina I - - 2011
Milk casein-derived bioactive tripeptides isoleucine-proline-proline (Ile-Pro-Pro) and valine-proline-proline (Val-Pro-Pro) lower blood pressure in animal models of hypertension and humans. In some studies, their angiotensin-converting enzyme (ACE)-inhibitory effect has been demonstrated. Besides classical ACE-angiotensin II-AT(1)-receptor pathway (ACE-Ang II- AT(1)), the significance of ACE2-angiotensin-(1-7)-Mas-receptor (ACE2-Ang-(1-7)-Mas) axis in the blood pressure regulation has ...
Milani Carlo J CJ Department of Physiology, Hypertension and Renal Center of Excellence, Tulane University Health Sciences Center, New Orleans, Louisiana 70112, - - 2010
Previous studies have demonstrated that the urinary excretion of angiotensinogen is significantly increased in ANG II-infused hypertensive rats, which is associated with an augmentation of intrarenal ANG II levels. These findings suggest that urinary angiotensinogen excretion rates provide an index of intrarenal ANG II levels in ANG II-dependent hypertensive states. ...
Jia Nan - - 2012
Aims: Oxidative stress and fibrosis is implicated in cardiac remodeling and failure. We tested whether allopurinol could decrease myocardial oxidative stress and attenuate cardiac fibrosis and left ventricular diastolic dysfunction in angiotensin II (AngII)-induced hypertensive mice. Methodology: We used 8-week-old male C57BL/6J mice, in which angiotensin II was subcutaneously infused ...
Capone Carmen - - 2011
Hypertension alters cerebrovascular regulation and increases the brain's susceptibility to stroke and dementia. We investigated the temporal relationships between the arterial pressure (AP) elevation induced by "slow pressor" angiotensin II (ANG II) infusion, which recapitulates key features of human hypertension, and the resulting cerebrovascular dysfunction. Minipumps delivering saline or ANG ...
Giani Jorge F - - 2011
Angiotensin (ANG)-(1-7) constitutes an important functional end-product of the renin-angiotensin-aldosterone system that acts to balance the physiological actions of ANG II. In the kidney, ANG-(1-7) exerts beneficial effects by inhibiting growth-promoting pathways and reducing proteinuria. We examined whether a 2-wk treatment with a daily dose of ANG-(1-7) (0.6 mg·kg(-1)·day(-1)) exerts ...
Iwamoto Mutsumi - - 2010
Connective tissue growth factor (CTGF) is a secreted protein that regulates fibrosis. We hypothesized that CTGF is induced in a pressure-overloaded (PO) heart and that blocking the angiotensin II type 1 receptor would reduce CTGF expression. Accordingly, we administered olmesartan and compared its effects with other antihypertensive drugs in a ...
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