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Results 601 - 618 of 618
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Aranda J V - - 1977
Blood pressure changes as a function of the rates of blood withdrawal and infusion were determined during exchange blood transfusion in 2 preterm newborn infants. 10 ml blood withdrawal and infusion completed within 3 minutes resulted in reversible changes in aortic pressure, whereas the same procedure completed within 45 to ...
Fagan D G - - 1977
The death of an adolescent after deliberate inhalation of the domestic fluorocarbon--lipid spray, PAM, triggered an investigation of the effects of this product on mammalian lung. Some of its constituents are known to destroy the lung-surfactant system, but death from its inhalation by earlier victims was usually attributed to the ...
Mauderly J L - - 1977
A procedure was developed for performing multiple-wash, saline, bronchopulmonary lavages in living small animals. Animals were anesthetized with halothane in oxygen, intubated with tracheal catheters made from intravenous cannulas, and maintained on a flow-through anesthetic system which allowed positive pressure ventilation and fluid instillation. Wash volumes were calculated from lung ...
Ikegami M - - 1977
The pressure-volume (PV) characteristics of 21 adult rat lungs were examined before and after lung washing after which natural or synthetic (dipalmitoyl lecithin (DPL)) surfactant was administered by either an ultrasonic nebulizer or instilled directly into the trachea. Lungs receiving surfactant by nebulization were ventilated at a rate of 40/min ...
Grossmann G - - 1977
The expansion pattern of the lungs of full-term and premature newborn rabbits was evaluated by direct observation of the lung surface during an inflation-deflation cycle, with particular reference to the effect of tracheal deposition of surfactant before the first breath. In non-treated premature fetuses, aeration of alveoli was initiated at ...
Betléri I - - 1977
Atelectasis and emhysema have been induced in rabbits after anaesthesia and IPPB for one hour at 30 cm water pressure. The pulmonary surfactant became coarsely granular and appeared in the form of large drops. A correlation is suggested to exist between this phenomenon and the atelectasis and emphysema which developed ...
Schürch S F - - 1976
Dionosil Oily (a suspension of propyliodone crystals in peanut oil and powdered tantalum were introduced into the right principal bronchi of rabbit lungs. The left lungs were used as controls. Pressure-volume characteristics of excised lungs with Dionosil Oily or peanut oil demonstrated significantly reduced compliance on inflation at a pressure ...
Faridy E E - - 1976
The effect of ventilation on movement of surfactant in airways was studied in rat lungs. Male albino rats were anesthetized and sacrificed by exsanguination. The trachea was cannulated and the diaphragm opened to allow the lungs to collapse. The lungs were left in chest and kept at minimal volume, or ...
Faridy E E - - 1976
The freshly excised lower lobes of lungs of dogs were washed by filling and emptying the lobe with isotonic saline. The wash fluid was then discarded and the procedure was repeated 9 times. The 9th wash was collected and used for measurements of surface tension and lecithin content. The lobe ...
Matthews W H - - 1976
A stable emulsion can be prepared by subjecting a mixture of 30% (by volume) FC-80 fluorocarbon; a 0.3-M THAM solution titrated to pH 7.4 with HCl; and 0.04 g F68 Pluronic surfactant per milliliter FC-80 to ultrasonic energy. The emulsion has a density of 1.24 g/ml; and absolute viscosity of ...
Perry J C - - 1975
The protective effect of a nonionic surface-active polyol agent (Pluronic F-68) against bolus injection and constant-rate IV infusion of air was studied in 21 dogs anesthetized with pentobarbital. Aortic, pulmonary artery and right ventricular pressures, cardiac output, end-tidal CO2 concentration, wasted ventilation, and blood surface tensions were measured before and ...
Starrett R W - - 1975
Left diaphragmatic hernias were produced surgically in ten control lambs at term, and in 19 lambs in 127-144 days' gestation. The hemodynamic and ventilatory changes that occur following delivery and attempted spontaneous breathing were noted. The herniated viscera effectively occluded the diaphragmatic defect, and all lambs were capable of developing ...
Caprino L - - 1975
The authors report the results of a series of investigations on the toxic effects produced in mice and rabbits by inhalation of Dimethyl-ether. Median lethal concentration (LC50) and Median lethal time (LT50) were determined in the mouse. Also the effects of DME inhalation on some physiological parameters (blood pressure, heart ...
Bergren D R - - 1975
Previous work has shown that short-term exposure of cats to oxygen at high pressure (OHP), to the extent of overt convulsive seizures, has little or no effect on the lung appearance or lung weight but does alter the alveolar surfactants. More prolonged exposure results in hemorrhagic edema of the cat ...
Sheffield P J - - 1975
The purpose of this investigation was to evaluate the effects on pulmonary surfactant in mice after long-duration exposure to 100% oxygen at various partial pressures equivalent to 842 mb (632) mmHg) or less. Six-month-old female CBA mice, weighing 25-35 g, were exposed to the pure oxygen environment. The effect on ...
Modanlou H - - 1974
Direct systolic, diastolic, and mean arterial blood pressure was continuously recorded during the first 64 min of life in 150 newborn infants. The data were analyzed at 4, 8, 16, 32, and 64 min. The highest blood pressure values were noted during the first few minutes of life in all ...
JACQUEZ J A - - 1959
The partial pressure of ammonia in alveolar air was measured and found to be the same (within the limits of experimental error) as the calculated partial pressure of ammonia in arterial plasma. It is likely that ammonia is equilibrated between alveolar air and the blood during its passage through the ...
SAUNDERS P R - - 1959
Moderate doses in rabbits produced hypotension, increased respiratory rate, and myocardial injury. Respiratory arrest occurred with fatal doses when the blood pressure had declined to very low values. The active substance (or substances) was nondialyzable, and the potency of the protein-containing lyophilized or glycerol-treated extracts was maintained well on prolonged ...
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